{"id":67631,"date":"2026-08-20T08:03:13","date_gmt":"2026-08-20T08:03:13","guid":{"rendered":"http:\/\/zydq.1006ss.com\/?p=67631"},"modified":"2026-08-20T08:03:13","modified_gmt":"2026-08-20T08:03:13","slug":"dr-u%e8%af%b4-%e6%af%8f%e4%b8%80%e4%b8%aa%e9%a3%8e%e9%99%a9%e4%ba%ba%e7%be%a4%e5%9d%87%e9%9c%80%e8%a6%81%e5%81%9a%e7%9a%84%e6%a3%80%e6%b5%8b%ef%bc%9a%e4%bd%8e%e5%af%86%e5%ba%a6%e8%84%82%e8%9b%8b","status":"publish","type":"post","link":"http:\/\/zydq.1006ss.com\/?p=67631","title":{"rendered":"Dr.U\u8bf4: \u6bcf\u4e00\u4e2a\u98ce\u9669\u4eba\u7fa4\u5747\u9700\u8981\u505a\u7684\u68c0\u6d4b\uff1a\u4f4e\u5bc6\u5ea6\u8102\u86cb\u767d\u4e9a\u578b\u5206\u6790"},"content":{"rendered":"
\"Dr.U\u8bf4:<\/figure>\n

\n

\u539f\u6587\u94fe\u63a5<\/a><\/strong><\/p>\n

\u968f\u7740\u4eba\u53e3\u8001\u9f84\u5316\u548c\u57ce\u9547\u5316\u8fdb\u7a0b\u7684\u52a0\u901f\u4ee5\u53ca\u5c45\u6c11\u4e0d\u5065\u5eb7\u7684\u751f\u6d3b\u65b9\u5f0f\uff0c\u6211\u56fd\u5fc3\u8840\u7ba1\u75c5\u7684\u53d1\u75c5\u4eba\u6570\u6301\u7eed\u589e\u52a0\uff0c\u6211\u56fd\u5fc3\u8840\u7ba1\u75c5\u60a3\u4eba\u6570\u8fbe2.9\u4ebf\uff0c\u6b7b\u4ea1\u7387\u5c45\u9996\u4f4d\uff0c\u9ad8\u4e8e\u80bf\u7624\u548c\u5176\u4ed6\u75be\u75c5\u3002<\/p>\n

\"Dr.U\u8bf4:\"Dr.U\u8bf4:<\/figure>\n

\n

\u8840\u8102\u5f02\u5e38\uff0c\u7279\u522b\u662f\u4f4e\u5bc6\u5ea6\u8102\u86cb\u767d\u80c6\u56fa\u9187\u542b\u91cf\u8d85\u6807\u5df2\u516c\u8ba4\u4e3a\u5fc3\u8840\u7ba1\u75c5\u7684\u72ec\u7acb\u5371\u9669\u56e0\u7d20\uff0c\u4e2d\u56fd\u6210\u4eba\u8840\u8102\u5f02\u5e38\u603b\u4f53\u60a3\u75c5\u7387\u9ad8\u8fbe40.4%\uff0c\u5e76\u968f\u5e74\u9f84\u589e\u52a0\u800c\u5347\u9ad8\u3002\u65e9\u671f\u68c0\u51fa\u8840\u8102\u5f02\u5e38\uff0c\u76d1\u6d4b\u8840\u8102\u6c34\u5e73\u53d8\u5316\uff0c\u662f\u6709\u6548\u9632\u6cbb\u5fc3\u8840\u7ba1\u75c5\u7684\u91cd\u8981\u57fa\u7840\u3002<\/p>\n

\n

01 \u4ec0\u4e48\u662f\u4f4e\u5bc6\u5ea6\u8102\u86cb\u767d<\/strong>
LDL\uff0c\u5373\u4f4e\u5bc6\u5ea6\u8102\u86cb\u767d\uff0c\u5b83\u4e0eHDL\u5f62\u6210\u9c9c\u660e\u5bf9\u6bd4\uff0c\u88ab\u79f0\u4e3a\u201c\u574f\u80c6\u56fa\u9187\u201d\uff0cLDL\u7684\u540d\u5b57\u540c\u6837\u63ed\u793a\u4e86\u5b83\u7684\u7279\u6027\uff1a\u201c\u4f4e\u5bc6\u5ea6\u201d\u610f\u5473\u7740\u5b83\u643a\u5e26\u7684\u80c6\u56fa\u9187\u8f83\u591a\uff0c\u800c\u86cb\u767d\u8d28\u8f83\u5c11\uff0c\u8fd9\u6837\u7684\u7ed3\u6784\u4f7f\u5f97\u5b83\u66f4\u5bb9\u6613\u5728\u8840\u7ba1\u58c1\u4e0a\u6c89\u79ef\u4e0b\u6765\u3002\u5bfc\u81f4\u52a8\u8109\u72ed\u7a84\u548c\u963b\u585e\uff0c\u589e\u52a0\u5fc3\u810f\u75c5\u98ce\u9669\u3002\u66f4\u4f4e\u7684LDL \u610f\u5473\u7740\u66f4\u4f4e\u7684\u5fc3\u810f\u75c5\u98ce\u9669\u3002\u5f53LDL\u5728\u8840\u7ba1\u58c1\u6c89\u79ef\u65f6\uff0c\u4f1a\u5438\u5f15\u8840\u6db2\u4e2d\u7684\u5176\u4ed6\u6210\u5206\uff0c\u5982\u767d\u7ec6\u80de\u548c\u8840\u5c0f\u677f\uff0c\u5f62\u6210\u4e00\u5c42\u539a\u539a\u7684\u6591\u5757\uff0c\u8fd9\u5c31\u662f\u6211\u4eec\u901a\u5e38\u6240\u8bf4\u7684\u52a8\u8109\u7ca5\u6837\u786c\u5316\u3002\u8fd9\u4e9b\u6591\u5757\u4f1a\u9010\u6e10\u7f29\u5c0f\u8840\u7ba1\u8154\uff0c\u5f71\u54cd\u8840\u6db2\u6d41\u901a\uff0c\u751a\u81f3\u53ef\u80fd\u7834\u88c2\uff0c\u5f15\u53d1\u8840\u6813\uff0c\u5bfc\u81f4\u5fc3\u810f\u75c5\u53d1\u4f5c\u6216\u4e2d\u98ce\u7b49\u4e25\u91cd\u540e\u679c\u3002\u56e0\u6b64\uff0cLDL\u88ab\u89c6\u4e3a\u5fc3\u8840\u7ba1\u5065\u5eb7\u7684\u5934\u53f7\u654c\u4eba\u3002<\/p>\n

\n

02 \u4f4e\u5bc6\u5ea6\u8102\u86cb\u767d\u4e9a\u578b\u5206\u6790<\/strong>
\u8102\u86cb\u767d\u4f20\u7edf\u68c0\u6d4b\u4e0d\u662f\u9884\u9632\u5fc3\u8840\u7ba1\u75be\u75c5\u7684\u6700\u597d\u6307\u6807\uff0c\u5927\u7ea6 50%\u7684\u5fc3\u8840\u7ba1\u75be\u75c5\u60a3\u8005\u7684\u8102\u7c7b\u6c34\u5e73\u663e\u793a\u6b63\u5e38\uff0c\u53ea\u670930%\u7684\u5fc3\u810f\u75c5\u60a3\u8005\u80fd\u591f\u6839\u636e\u68c0\u6d4b\u603b\u80c6\u56fa\u9187\u542b\u91cf\u88ab\u53d1\u73b0\uff0c\u66f4\u591a\u4f4e\u5bc6\u5ea6\u548c\u9ad8\u5bc6\u5ea6\u8102\u86cb\u767d\u6b63\u5e38\u7684\u60a3\u8005\u4ecd\u7136\u6709\u60a3\u5fc3\u8840\u7ba1\u75be\u75c5\u7684\u98ce\u9669\u3002\u6839\u636e\u73b0\u884c\u7684\u56fd\u9645ATP III\u68c0\u6d4b\u6807\u51c6\uff0c\u5927\u591a\u6570\u7684\u5fc3\u8840\u7ba1\u75be\u75c5\u4e0d\u80fd\u88ab\u68c0\u6d4b\u5230\u3002<\/p>\n

\"Dr.U\u8bf4:\"Dr.U\u8bf4:<\/figure>\n

\n

\u25b2\u540c\u6837\u7684\u4f4e\u5bc6\u5ea6\u8102\u86cb\u767d\u80c6\u56fa\u9187\u6570\u503c\uff0c\u4e0d\u4e00\u6837\u7684\u5fc3\u8840\u7ba1\u75c5\u53d8\u98ce\u9669<\/p>\n

\u7814\u7a76\u53d1\u73b0\uff0c\u4f4e\u5bc6\u5ea6\u548c\u9ad8\u5bc6\u5ea6\u8102\u86cb\u767d\u5b58\u5728\u8bf8\u591a\u4e9a\u7ec4\u5206\uff0c\u5bf9\u4e8e\u4f4e\u5bc6\u5ea6\u8102\u86cb\u767d\u7684\u4e9a\u7ec4\u5206\u800c\u8a00\uff0c\u00a0\u4e00\u4e9b\u5927\u7684\u4f4e\u5bc6\u5ea6\u8102\u86cb\u767d\u8d1f\u8d23\u6b63\u5e38\u7684\u80c6\u56fa\u9187\u8fd0\u8f93\uff0c\u88ab\u8ba4\u4e3a\u662f\u201c\u6b63\u5e38\u7684 LDL\u201d\uff0c\u800c\u4e00\u4e9b\u5c0f\u800c\u5bc6\u7684\u4f4e\u5bc6\u5ea6\u8102\u86cb\u767d(sdLDL)\u88ab\u8ba4\u4e3a\u662f\u201c\u4e0d\u597d\u7684\u6216\u975e\u6b63\u5e38\u7684 LDL\u201d\uff0c\u5b83\u4eec\u6613\u5f62\u6210\u6c27\u5316\u578b\u4f4e\u5bc6\u5ea6\u8102\u86cb\u767d\uff08OX-LDL\uff09\u4f7f\u5176\u643a\u5e26\u7684\u80c6\u56fa\u9187\u6c89\u79ef\u5230\u5fc3\u8111\u7b49\u90e8\u4f4d\u7684\u52a8\u8109\u58c1\u4e0a\u5f62\u6210\u7ca5\u6837\u6591\u5757\uff0c\u4ece\u800c\u4f1a\u5bfc\u81f4\u5fc3\u8840\u7ba1\u75be\u75c5\u7684\u4ea7\u751f\u3002\u5355\u4e00\u6d4b\u5b9a\u603b\u7684\u4f4e\u5bc6\u5ea6\u8102\u86cb\u767d\u542b\u91cf\u5e76\u4e0d\u80fd\u663e\u793a\u60a3\u5fc3\u8840\u7ba1\u75be\u75c5\u7684\u98ce\u9669\uff0c\u56e0\u4e3a\u5b83\u4e0d\u80fd\u533a\u5206\u201c\u5927\u7684\u201d\u548c\u201c\u5c0f\u800c\u5bc6\u7684\u201d\u4f4e\u5bc6\u5ea6\u8102\u86cb\u767d\uff0c\u5373\u4f7f\u603b\u7684\u4f4e\u5bc6\u5ea6\u8102\u86cb\u767d\u6c34\u5e73\u663e\u793a\u6b63\u5e38\uff0c\u5176\u4e2d\u7684\u201c\u5c0f\u800c\u5bc6\u7684\u201d\u4f4e\u5bc6\u5ea6\u8102\u86cb\u767d\u53ef\u4ee5\u4f7f\u60a3\u5fc3\u8840\u7ba1\u75be\u75c5\u7684\u98ce\u9669\u8fbe\u52303\u500d\u4ee5\u4e0a\u3002\u56e0\u6b64\uff0c\u8840\u8102\u86cb\u767d\u7684\u7ec6\u5206\u7c7b\u53ca\u5176\u5b9a\u91cf\u5206\u6790\u5728\u9884\u6d4b\u5fc3\u8840\u7ba1\u75be\u75c5\u98ce\u9669\u4e2d\u53d1\u6325\u7740\u81f3\u5173\u91cd\u8981\u7684\u4f5c\u7528\u3002\u00a0<\/mark><\/p>\n

\"Dr.U\u8bf4:\"Dr.U\u8bf4:<\/figure>\n

\n

\u900f\u8fc7\u4e2a\u6027\u5316\u7684\u4f4e\u5bc6\u5ea6\u8102\u86cb\u767d\u4e9a\u578b\u5206\u6790(LDL Subfractions) ,\u53ef\u4ee5\u65e9\u671f\u8bca\u65ad\u51fa\u5c06\u6765\u53d1\u5c55\u51a0\u72b6\u52a8\u8109\u75be\u75c5\u7684\u98ce\u9669,\u5e76\u4e14\u9488\u5bf9\u4e0d\u540c\u7684\u98ce\u9669\u5efa\u7acb\u4e13\u5c5e\u7684\u6cbb\u7597\u5bf9\u7b56,\u5ef6\u957f\u5065\u5eb7\u5bff\u547d\u3002<\/p>\n

\n

03 \u4e0e\u4f20\u7edf\u68c0\u6d4b\u6709\u4ec0\u4e48\u4e0d\u540c<\/strong>
\u6211\u4eec\u5148\u6765\u89e3\u8bfb\u8fd9\u4efdLDL\u4e9a\u578b\u5206\u6790\u7684\u56fe\u8c31\uff1a<\/p>\n

\"Dr.U\u8bf4:\"Dr.U\u8bf4:<\/figure>\n

1\u3001\u6b64\u62a5\u544a\u5171\u5206\u6790\u5341\u4e8c\u79cd\u8102\u86cb\u767d\u4e9a\u578b\uff1aVLDL , MIDCBA , LDL1-7 , HDL \u3002<\/p>\n

2\u3001VLDL\u542b\u5927\u91cf\u4e09\u9170\u7518\u6cb9\u916f\u8102\u86cb\u767d\uff0c\u6b64\u6307\u6807\u4e0e\u9ad8\u8840\u7cd6\u3001\u8840\u8102\u5f02\u5e38\u6709\u5bc6\u5207\u5173\u8054\uff0c\u662f\u4fc3\u8fdb\u52a8\u8109\u7ca5\u6837\u786c\u5316\u5371\u9669\u56e0\u5b50\u3002<\/p>\n

3\u3001MID\u5305\u542b\u4e86rVLDL(\u6781\u4f4e\u5bc6\u5ea6\u8102\u86cb\u767d\u6b8b\u4f53)\u548c\u4e24\u79cdIDL\uff08\u4e2d\u95f4\u5bc6\u5ea6\u8102\u86cb\u767d\uff09\u3002MID\u4e0e\u5bfc\u81f4\u52a8\u8109\u786c\u5316\u7684\u7b2c\u4e09\u578b\u8840\u8102\u5f02\u5e38\u5408\u5e76\u9ad8\u8102\u86cb\u767d\u8840\u75c7\u6709\u5173\uff0c\u4fc3\u8fdb\u52a8\u8109\u7ca5\u6837\u786c\u5316\u98ce\u9669\u8f83\u9ad8\u3002<\/p>\n

4\u3001LDL1-2\u4ee3\u8868\u201c\u5927\u800c\u677e\u6563\u201d\u7684\u4f4e\u5bc6\u5ea6\u8102\u86cb\u767d\uff0c\u4fc3\u8fdb\u52a8\u8109\u7ca5\u6837\u786c\u5316\u548c\u5fc3\u8840\u7ba1\u75be\u75c5\u98ce\u9669\u8f83\u4f4e\u3002<\/p>\n

5\u3001LDL3-7\u4ee3\u8868\u201c\u5c0f\u800c\u5bc6\u201d\u7684\u4f4e\u5bc6\u5ea6\u8102\u86cb\u767d\u80c6\u56fa\u9187\u542b\u91cf\uff0c\u6709\u4e09\u500d\u5fc3\u8840\u7ba1\u75be\u75c5\u3001\u4ee3\u8c22\u75c7\u5019\u7fa4\u53ca\u7cd6\u5c3f\u75c5\u98ce\u9669\u3002<\/p>\n

6\u3001HDL\u4ee3\u8868\u597d\u7684\u80c6\u56fa\u9187\uff0c\u5bf9\u5fc3\u8840\u7ba1\u75be\u75c5\u5177\u4fdd\u62a4\u4f5c\u7528\uff0c\u6570\u503c\u504f\u4f4e\u4f1a\u6709\u51a0\u5fc3\u75c5\u7684\u98ce\u9669\u3002<\/p>\n

7\u3001LDL profifile\u4f1a\u663e\u793a\u60a8\u7684\u4f4e\u5bc6\u5ea6\u8102\u86cb\u767d\u662f\u5c5e\u4e8eType A\u6216\u662f\u5c5e\u4e8eType B\uff1a<\/p>\n

Type A(\u5177\u6709\u4f4e\u98ce\u9669\u5927\u9897\u7c92\u677e\u6563\u578b\uff09<\/p>\n

Type B(\u5177\u6709\u9ad8\u98ce\u9669\u5c0f\u9897\u7c92\u7d27\u5bc6\u578b\uff09<\/p>\n

8\u3001Total Cho\u4e3a\u8840\u4e2d\u80c6\u56fa\u9187\u7efc\u5408\u6d53\u5ea6\u3002Total LDL\u5305\u542b\u4e86MIDCBA\u548cLDL1-7\u80c6\u56fa\u9187\u603b\u91cf\u3002<\/p>\n

\n

04 \u9002\u5b9c\u4eba\u7fa4<\/strong>
\u91cd\u70b9\u68c0\u6d4b\u4eba\u7fa4\uff1e55 \u5c81\uff1b
\u5177\u6709\u9057\u4f20\u6027\u5bb6\u65cf\u5fc3\u810f\u75c5\u53f2\u7684\u4eba\uff1b
\u5438\u70df\u4eba\u58eb\u3001\u4e0d\u7231\u8fd0\u52a8\u3001\u80a5\u80d6\u548c\u8d85\u91cd\u4ee5\u53ca\u7cd6\u5c3f\u75c5\u60a3\u8005\uff1b
\u9ad8\u8840\u538b\u3001\u9ad8\u8840\u8102\u6216\u9ad8\u7518\u6cb9\u4e09\u916f\u4eba\u7fa4\uff1b
\u603b\u80c6\u56fa\u9187\u542b\u91cf\u6b63\u5e38\uff0c\u4f4e\u5bc6\u5ea6\u8102\u86cb\u767d\u80c6\u56fa\u9187\u542b\u91cf\u8d85\u6807\u8005\uff1b
\u670d\u7528\u836f\u7269\u6765\u8c03\u8282\u80c6\u56fa\u9187\u7684\u60a3\u8005\u3002<\/p>\n

\"Dr.U\u8bf4:\"Dr.U\u8bf4:<\/figure>\n

\n

\u4f4e\u5bc6\u5ea6\u8102\u86cb\u767d\u80c6\u56fa\u9187(LDL-C)\u4e00\u76f4\u88ab\u8ba4\u4e3a\u662f\u5fc3\u8840\u7ba1\u75be\u75c5\u7684\u5371\u9669\u56e0\u5b50\uff0c\u5176\u6d53\u5ea6\u8d8a\u9ad8\uff0c\u81f4\u75c5\u98ce\u9669\u4e5f\u8d8a\u9ad8\uff0c\u4f46\u5b9e\u9645\u4e0a\u4e00\u822c\u7684\u8840\u8102\u68c0\u9a8c\u5bf9\u52a8\u8109\u7ca5\u72b6\u786c\u5316\u7684\u9884\u6d4b\u6027\u4e0d\u523050%\uff0c\u751a\u81f3\u6709\u8fd175%\u5fc3\u808c\u6897\u585e\u7684\u75c5\u4eba\u5176\u4f4e\u5bc6\u5ea6\u8102\u86cb\u767d\u80c6\u56fa\u9187\u4e0e\u9ad8\u5bc6\u5ea6\u8102\u86cb\u767d\u80c6\u56fa\u9187(HDL-C)\u7686\u5728\u6b63\u5e38\u8303\u56f4\u4e4b\u5185\u3002\u56e0\u6b64\uff0c\u6211\u4eec\u9700\u8981\u66f4\u591a\u8f85\u52a9\u8bc4\u4f30\u65b9\u5f0f\u3002\u4f4e\u5bc6\u5ea6\u8102\u86cb\u767d\u4e9a\u578b\u5206\u6790\u4e2d\u5305\u542b\u4e86\u57fa\u672c\u7684\u80c6\u56fa\u9187\u68c0\u6d4b\uff0c\u8fd8\u4ee5\u5bc6\u5ea6\u548c\u9897\u7c92\u5927\u5c0f\u5206\u6790\u9ad8\u7518\u6cb9\u4e09\u916f\u8102\u86cb\u767d\u3001\u5927\u9897\u7c92\u677e\u6563\u4f4e\u5bc6\u5ea6\u8102\u86cb\u767d\u53ca\u5c0f\u9897\u7c92\u7d27\u5bc6\u4f4e\u5bc6\u5ea6\u8102\u86cb\u767d\uff0c\u80fd\u66f4\u8fdb\u4e00\u6b65\u5730\u8bc4\u4f30\u7f79\u60a3\u5fc3\u8840\u7ba1\u75be\u75c5\u7684\u98ce\u9669\u3002<\/p>\n

\u6b22\u8fce\u60a8\u901a\u8fc7\u300aDr.U\u8bf4\u300b\u4e86\u89e3\u5230\u79d1\u5b66\u3001\u6b63\u786e\u7684\u5065\u5eb7\u89c2\u5ff5\uff0c\u4e3a\u60a8\u7684\u4eb2\u4eba\u548c\u5bb6\u5ead\u5e26\u6765\u5e2e\u52a9\uff0c\u613f\u60a8\u70ed\u7231\u751f\u547d\u5065\u5eb7\uff0c\u5e76\u4eab\u53d7\u81ea\u7531\u4eba\u751f\u3002<\/p>\n

\n

\u53c2\u8003\u6587\u732e\uff1a
[1] \u56fd\u5bb6\u5fc3\u8840\u7ba1\u75c5\u4e2d\u5fc3. \u4e2d\u56fd\u5fc3\u8840\u7ba1\u75c5\u62a5\u544a 2018[M]. \u5317\u4eac\uff1a\u4e2d\u56fd\u5927\u767e\u79d1\u5168\u4e66\u51fa\u7248\u793e\uff0c2019.<\/p>\n

[2] \u4e2d\u56fd\u6210\u4eba\u8840\u8102\u5f02\u5e38\u9632\u6cbb\u6307\u5357\u4fee\u8ba2\u8054\u5408\u59d4\u5458\u4f1a. \u4e2d\u56fd\u6210\u4eba\u8840\u8102\u5f02\u5e38\u9632\u6cbb\u6307\u5357\uff082016 \u5e74\u4fee\u8ba2<\/p>\n

\u7248\uff09[J]. \u4e2d\u56fd\u5faa\u73af\u6742\u5fd7\uff0c2016,31(10):937-953.<\/p>\n

[3] Fern\u00e1ndez-Friera L, Fuster V, L\u00f3pez-Melgar B, et al. Normal LDL-Cholesterol Levels Are Associated With Subclinical Atherosclerosis in the Absence of Risk Factors[J]. Journal of the American College of Cardiology, 2017, 70(24): 2979-2991.[4] Fukushima Y, Hirayama S, et al. Small dense LDL cholesterol is a robust therapeutic marker of<\/p>\n

statin treatment in patients with acute coronary syndrome and metabolic syndrome[J]. Clin Chim Acta. 2011 Jul 15;412(15-16):1423-7.[5] Ivanova EA, Myasoedova VA, et al. Small dense low-density lipoprotein as biomarker for atherosclerotic diseases[J]. Oxid Med Cell Longev, 2017;2017:1273042.[6] Sakai K, Koba S, et al. Small dense low-density lipoprotein cholesterol is a promising biomarker<\/p>\n

for secondary prevention in older men with stable coronary artery disease[J]. Geriatr Gerontol Int.2018 Jun;18(6):965-972.[7] Shiffman D, Louie JZ, et al. LDL subfractions are associated with incident cardiovasculardisease in the Malm\u00f6 Prevention Project Study[J]. Atherosclerosis. 2017 Aug;263:287-292.[8] Zhao X, Zhang HW, et al. Analysis of Lipoprotein Subfractions in 920 Patients With and WithoutType 2 Diabetes. Heart Lung<\/p>\n

\u200b<\/p>\n","protected":false},"excerpt":{"rendered":"

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