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class=\"wp-block-paragraph\">\u8fd9\u9879\u7814\u7a76\u662f\u9488\u5bf9\u4eba\u7c7b\u767d\u8840\u75c5\u7ec6\u80de\u8fdb\u884c\u7684\uff0c\u5229\u7528\u5c0f\u9f20\u8fdb\u884c\u7684\u52a8\u7269\u5b9e\u9a8c\u8868\u660e\uff0c\u9ad8\u6d53\u5ea6\u7684\u7ef4\u751f\u7d20C\u5177\u6709\u6291\u5236\u8840\u7ba1\u751f\u6210\u7684\u4f5c\u7528\uff0c\u4ece\u800c\u6291\u5236\u767d\u8840\u75c5\u7ec6\u80de\u7684\u589e\u6b96\u3002\u8fd9\u662f\u4e00\u79cd\u6291\u5236\u4e00\u79cd\u540d\u4e3a HIF1\u03b1 \u7684\u5206\u5b50\u8868\u8fbe\u7684\u673a\u5236\uff0c\u8fd9\u79cd\u5206\u5b50\u4f1a\u6291\u5236 VEGF\uff08\u4e00\u79cd\u53c2\u4e0e\u8840\u7ba1\u751f\u6210\u7684\u5206\u5b50\uff09\uff0c\u6700\u7ec8\u6291\u5236\u8840\u7ba1\u751f\u6210\u5e76\u6291\u5236\u767d\u8840\u75c5\u7684\u8fdb\u5c55\u3002<\/p>\n<p class=\"wp-block-paragraph\">\u8be5\u7814\u7a76\u6210\u679c\u672a\u6765\u5c06\u968f\u7740\u9ad8\u6d53\u5ea6\u7ef4\u751f\u7d20C\u6297\u80bf\u7624\u65b0\u673a\u5236\u7684\u53d1\u73b0\u800c\u5907\u53d7\u5173\u6ce8\u3002<\/p>\n<figure class=\"wp-block-image\"><img decoding=\"async\" title=\"\u5bf9\u4e8e\u764c\u75c7\u7684\u9ad8\u6d53\u5ea6\u7ef4\u751f\u7d20C\u70b9\u6ef4\u7597\u6cd5 - \u7b2c6\u5f20  | \u4e2d\u836f\u517b\u751f\u77e5\u8bc6-\u4e2d\u8349\u836f\u7684\u529f\u6548\u4e0e\u4f5c\u7528\" alt=\"\u5bf9\u4e8e\u764c\u75c7\u7684\u9ad8\u6d53\u5ea6\u7ef4\u751f\u7d20C\u70b9\u6ef4\u7597\u6cd5 - \u7b2c6\u5f20  | \u4e2d\u836f\u517b\u751f\u77e5\u8bc6-\u4e2d\u8349\u836f\u7684\u529f\u6548\u4e0e\u4f5c\u7528\" src=\"\/\/www.w3.org\/2000\/svg&#039;%20width=&#039;0&#039;%20height=&#039;0&#039;%20viewBox=&#039;0%200%200%200&#039;%3E%3C\/svg%3E\" class=\"perfmatters-lazy\" data-src=\"https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/Hmia0qCnCyoW1fowd0MZdxhP2xtuotoeib9aFuDHOvRWECUibLwDGfkR01AUicS5NvIiajqA4t1HqQ7UF0iad2iaEC94w\/640?wx_fmt=png&amp;from=appmsg&amp;tp=wxpic&amp;wxfrom=10005&amp;wx_lazy=1#imgIndex=3\" \/><img decoding=\"async\" title=\"\u5bf9\u4e8e\u764c\u75c7\u7684\u9ad8\u6d53\u5ea6\u7ef4\u751f\u7d20C\u70b9\u6ef4\u7597\u6cd5 - \u7b2c7\u5f20  | \u4e2d\u836f\u517b\u751f\u77e5\u8bc6-\u4e2d\u8349\u836f\u7684\u529f\u6548\u4e0e\u4f5c\u7528\" alt=\"\u5bf9\u4e8e\u764c\u75c7\u7684\u9ad8\u6d53\u5ea6\u7ef4\u751f\u7d20C\u70b9\u6ef4\u7597\u6cd5 - \u7b2c7\u5f20  | \u4e2d\u836f\u517b\u751f\u77e5\u8bc6-\u4e2d\u8349\u836f\u7684\u529f\u6548\u4e0e\u4f5c\u7528\" src=\"https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/Hmia0qCnCyoW1fowd0MZdxhP2xtuotoeib9aFuDHOvRWECUibLwDGfkR01AUicS5NvIiajqA4t1HqQ7UF0iad2iaEC94w\/640?wx_fmt=png&amp;from=appmsg&amp;tp=wxpic&amp;wxfrom=10005&amp;wx_lazy=1#imgIndex=3\" \/><\/figure>\n<p class=\"wp-block-paragraph\">\n<p class=\"wp-block-paragraph\"><strong>\u9ad8\u6d53\u5ea6\u7ef4\u751f\u7d20C\u6ef4\u6ce8\u7597\u6cd5\u7684\u9884\u671f\u6548\u679c<\/strong><\/p>\n<p class=\"wp-block-paragraph\"><strong>1<\/strong> <strong>\u6740\u6b7b\u764c\u7ec6\u80de\u7684\u4f5c\u7528<\/strong>: \u76ee\u524d\u8fd8\u6ca1\u6709\u8db3\u591f\u7684\u6570\u636e\u8868\u660e\u8fd9\u79cd\u7597\u6cd5\u7684\u6548\u679c\u5982\u4f55\u3002\u867d\u7136\u5df2\u6709\u6709\u6548\u6027\u6848\u4f8b\u7684\u62a5\u9053\uff0c\u4f46\u8fd8\u9700\u8981\u672a\u6765\u7684\u4e34\u5e8a\u8bd5\u9a8c\u6765\u9a8c\u8bc1\u3002\u73b0\u9636\u6bb5\uff0c\u4e0d\u80fd\u8bf4\u5b83\u5bf9\u6240\u6709\u764c\u75c7\u90fd\u540c\u6837\u6709\u6548\uff0c\u4f46\u6709\u53ef\u80fd\u901a\u8fc7\u4e0e\u6807\u51c6\u6cbb\u7597\u76f8\u7ed3\u5408\u6765\u589e\u52a0\u6cbb\u7597\u6548\u679c\uff0c\u6216\u8005\u5728\u6807\u51c6\u6cbb\u7597\u65e0\u6548\u7684\u60c5\u51b5\u4e0b\u53ef\u4ee5\u5355\u72ec\u4f7f\u7528\u3002<\/p>\n<p class=\"wp-block-paragraph\">\n<p class=\"wp-block-paragraph\"><strong>2<\/strong> <strong>\u764c\u75c7\u6cbb\u7597\u51e0\u4e4e\u6ca1\u6709\u526f\u4f5c\u7528<\/strong>: <mark class=\"has-inline-color has-vivid-red-color\">\u5bf9\u4e8e\u6c34\u8d1f\u8377\u5bfc\u81f4\u5168\u8eab\u72b6\u51b5\u6076\u5316\u7684\u60c5\u51b5\uff0c\u5982\u5fc3\u529b\u8870\u7aed\u3001\u80be\u529f\u80fd\u8870\u7aed\u6216\u660e\u663e\u80f8\u8179\u6c34\uff0c\u4e0d\u80fd\u91c7\u7528\u9ad8\u6d53\u5ea6\u7ef4\u751f\u7d20C\u6ef4\u6ce8\u7597\u6cd5\u3002<\/mark>\u7ef4\u751f\u7d20C\u672c\u8eab\u6ca1\u6709\u4efb\u4f55\u91cd\u5927\u526f\u4f5c\u7528\uff0c\u56e0\u6b64\u5982\u679c\u9075\u5faa\u6b63\u786e\u7684\u8ba1\u5212\uff0c\u51e0\u4e4e\u4e0d\u4f1a\u51fa\u73b0\u4e25\u91cd\u7684\u526f\u4f5c\u7528\u3002<mark class=\"has-inline-color has-vivid-red-color\">\u4e0e\u6297\u764c\u836f\u7269\u548c\u653e\u5c04\u6cbb\u7597\u76f8\u6bd4\uff0c\u7ef4\u751f\u7d20C\u7597\u6cd5\u7684\u526f\u4f5c\u7528\u975e\u5e38\u8f7b\u5fae\u3002<\/mark>\u6297\u764c\u836f\u7269\u548c\u653e\u5c04\u6cbb\u7597\u4e0d\u4ec5\u4f1a\u635f\u5bb3\u80bf\u7624\u7ec6\u80de\uff0c\u8fd8\u4f1a\u635f\u5bb3\u6b63\u5e38\u7ec6\u80de\u3002\u5728\u8fd9\u65b9\u9762\uff0c\u9ad8\u6d53\u5ea6\u7ef4\u751f\u7d20C\u6ef4\u6ce8\u7597\u6cd5\u4e0e\u4f20\u7edf\u764c\u75c7\u6cbb\u7597\u7684\u4e0d\u540c\u4e4b\u5904\u5728\u4e8e\uff0c\u5b83\u5bf9\u6b63\u5e38\u7ec6\u80de\u51e0\u4e4e\u4e0d\u4f1a\u9020\u6210\u635f\u5bb3\u3002<\/p>\n<p class=\"wp-block-paragraph\">\n<p class=\"wp-block-paragraph\"><strong>3<\/strong> <strong>\u53ef\u4ee5\u4e0e\u6297\u764c\u836f\u7269\u548c\u653e\u5c04\u6cbb\u7597\u8054\u5408\u4f7f\u7528<\/strong>: \u5f53\u4f7f\u7528\u653e\u5c04\u6cbb\u7597\u65f6\uff0c\u76ae\u80a4\u635f\u4f24\u51e0\u4e4e\u662f\u4e0d\u53ef\u907f\u514d\u7684\uff0c\u5c3d\u7ba1\u4e25\u91cd\u7a0b\u5ea6\u53ef\u80fd\u6709\u6240\u4e0d\u540c\u3002\u7ed3\u5408\u9ad8\u6d53\u5ea6\u7ef4\u751f\u7d20C\u6ef4\u6ce8\u6cbb\u7597\uff0c\u53ef\u51cf\u8f7b\u75c5\u60c5\u5e76\u52a0\u5feb\u5eb7\u590d\u901f\u5ea6\u3002\u5bf9\u4e8e\u5973\u6027\u6765\u8bf4\uff0c\u6297\u764c\u836f\u7684\u4f7f\u7528\u5e38\u5e38\u4f1a\u7ed9\u5979\u4eec\u5e26\u6765\u7cbe\u795e\u8d1f\u62c5\uff0c\u4e0d\u4ec5\u662f\u75be\u75c5\uff0c\u8fd8\u6709\u5316\u5986\u54c1\uff0c\u4f46\u5982\u679c\u8fd9\u79cd\u8d1f\u62c5\u80fd\u51cf\u8f7b\u4e00\u70b9\uff0c\u6211\u8ba4\u4e3a\u53ef\u4ee5\u7ed3\u5408\u4f7f\u7528\u3002\u8fd8\u6709\u6570\u636e\u8868\u660e\uff0c\u7ef4\u751f\u7d20C\u53ef\u4ee5\u51cf\u5c11\u67d0\u4e9b\u6297\u764c\u836f\u7269\u7684\u526f\u4f5c\u7528\uff0c\u589e\u5f3a\u5176\u6297\u80bf\u7624\u4f5c\u7528\u3002<\/p>\n<p class=\"wp-block-paragraph\">\u5bf9\u4e8e\u9632\u6b62\u8425\u517b\u72b6\u51b5\u548c\u5168\u8eab\u72b6\u51b5\u6076\u5316\u4e5f\u5177\u6709\u91cd\u8981\u610f\u4e49\u3002\u8425\u517b\u72b6\u51b5\u548c\u5168\u8eab\u72b6\u51b5\u7684\u6076\u5316\u4f1a\u5bfc\u81f4\u6297\u764c\u836f\u7269\u7684\u7528\u91cf\u53d7\u5230\u9650\u5236\uff0c\u6709\u65f6\u8fd8\u4f1a\u5bfc\u81f4\u6cbb\u7597\u65e0\u6cd5\u5982\u671f\u8fdb\u884c\u3002\u6362\u53e5\u8bdd\u8bf4\uff0c\u5b83\u6210\u4e3a\u963b\u788d\u764c\u75c7\u6cbb\u7597\u7684\u4e00\u4e2a\u539f\u56e0\u3002\u76f8\u53cd\uff0c\u4fdd\u6301\u8425\u517b\u548c\u603b\u4f53\u5065\u5eb7\u72b6\u51b5\u4e5f\u662f\u63a5\u53d7\u66f4\u5f3a\u7684\u764c\u75c7\u6cbb\u7597\uff08\u6807\u51c6\u6cbb\u7597\uff09\u7684\u6761\u4ef6\u3002\u9ad8\u6d53\u5ea6\u7ef4\u751f\u7d20C\u6ef4\u6ce8\u7597\u6cd5\u662f\u53ef\u4ee5\u5728\u8fd9\u65b9\u9762\u505a\u51fa\u8db3\u591f\u8d21\u732e\u7684\u6cbb\u7597\u65b9\u6cd5\u3002<\/p>\n<p class=\"wp-block-paragraph\">\u6b64\u5916\uff0c\u9ad8\u6d53\u5ea6\u7ef4\u751f\u7d20C\u6ef4\u6ce8\u7597\u6cd5\u5df2\u88ab\u4e34\u5e8a\u8bc1\u5b9e\u5177\u6709\u6b62\u75db\u4f5c\u7528\u3002\u4eba\u4eec\u8ba4\u4e3a\u5176\u4e2d\u6d89\u53ca\u591a\u79cd\u673a\u5236\uff0c\u5305\u62ec\u901a\u8fc7\u95f4\u63a5\u4fc3\u8fdb\u7c7b\u56fa\u9187\u4ea7\u751f\u3001\u964d\u4f4e\u8840\u9499\u6c34\u5e73\u548c\u4fc3\u8fdb\u9aa8\u9abc\u5438\u6536\u9499\u6765\u53d1\u6325\u6297\u708e\u4f5c\u7528\u3002<\/p>\n<p class=\"wp-block-paragraph\">\n<p class=\"wp-block-paragraph\"><strong>4<\/strong> <strong>\u4f5c\u4e3a\u6297\u5e94\u6fc0\u7269\u8d28\u7684\u4f5c\u7528<\/strong>: \u75be\u75c5\u7684\u76f4\u63a5\u538b\u529b\u3001\u60a3\u764c\u75c7\u7684\u7cbe\u795e\u538b\u529b\u3001\u6297\u764c\u836f\u7269\u7b49\u6cbb\u7597\u7684\u538b\u529b\u3002\u764c\u75c7\u60a3\u8005\u5728\u8eab\u4f53\u548c\u7cbe\u795e\u4e0a\u90fd\u9762\u4e34\u7740\u5f88\u5927\u7684\u538b\u529b\u3002\u538b\u529b\u4f1a\u6d88\u8017\u4f53\u5185\u7684\u7ef4\u751f\u7d20C\uff0c\u4ece\u800c\u524a\u5f31\u60a8\u7684\u514d\u75ab\u7cfb\u7edf\uff0c\u4f7f\u60a8\u66f4\u5bb9\u6613\u53d7\u5230\u538b\u529b\u7684\u5f71\u54cd\u3002\u764c\u75c7\u60a3\u8005\u6bd4\u5065\u5eb7\u4eba\u9700\u8981\u66f4\u591a\u7684\u7ef4\u751f\u7d20C\u6765\u7f13\u89e3\u7cbe\u795e\u538b\u529b\u548c\u589e\u5f3a\u514d\u75ab\u529b\u3002<\/p>\n<p class=\"wp-block-paragraph\">\n<p class=\"wp-block-paragraph\"><strong>5<\/strong> <strong>\u63d0\u9ad8\u514d\u75ab\u529b<\/strong>: \u7ef4\u751f\u7d20C\u4e5f\u662f\u63a7\u5236\u514d\u75ab\u529b\u7684\u7ef4\u751f\u7d20\uff0c\u56e0\u6b64\u5f53\u5982\u4e0a\u6240\u8ff0\u7f3a\u4e4f\u65f6\uff0c\u5c31\u4f1a\u51fa\u73b0\u514d\u75ab\u529b\u4e0b\u964d\u3001\u5bb9\u6613\u611f\u67d3\u3001\u4f24\u53e3\u96be\u4ee5\u6108\u5408\u7b49\u95ee\u9898\u3002\u8865\u5145\u7ef4\u751f\u7d20C\u8fd8\u53ef\u4ee5\u51cf\u5c11\u8fd9\u4e9b\u5e76\u53d1\u75c7\u7684\u53d1\u751f\u9891\u7387\u3002<\/p>\n<p class=\"wp-block-paragraph\">\n<p class=\"wp-block-paragraph\"><strong>6<\/strong> <strong>\u6cbb\u7597<\/strong>: <mark class=\"has-inline-color has-vivid-red-color\">\u6cbb\u7597\u5f00\u59cb\u65f6\uff0c\u6807\u51c6\u8f93\u6ce8\u9891\u7387\u4e3a\u6bcf\u5468 2\u81f33\u6b21\u3002<\/mark>\u5bf9\u4e8e\u6b63\u5728\u63a5\u53d7\u6297\u764c\u836f\u7269\u6216\u653e\u5c04\u6cbb\u7597\u7684\u60a3\u8005\u6216\u4ec5\u63a5\u53d7\u8fd9\u79cd\u6cbb\u7597\u7684\u60a3\u8005\uff0c\u9759\u8109\u6cbb\u7597\u7684\u6b21\u6570\u76f8\u540c\u3002\u591a\u6570\u60c5\u51b5\u4e0b\uff0c\u7ef4\u751f\u7d20C\u4e00\u6b21\u9759\u8109\u6ef4\u6ce850\u514b\u4ee5\u4e0a\u3002\u8f93\u6ce8\u65f6\u95f4\u6839\u636e\u7ef4\u751f\u7d20C\u7684\u5242\u91cf\u800c\u53d8\u5316\uff0c\u4e00\u822c\u662f1-2\u5c0f\u65f6\u3002<mark class=\"has-inline-color has-vivid-red-color\">\u4e00\u65e6\u764c\u75c7\u5b8c\u5168\u6d88\u5931\uff0c\u6cbb\u7597\u5c06\u7ee7\u7eed\u6bcf\u5468\u4e00\u6b21\uff0c\u6301\u7eed\u7ea6\u516d\u4e2a\u6708\u3002\u4e4b\u540e\u9010\u6e10\u51cf\u5c11\u9891\u7387\uff0c\u5982\u6bcf\u4e24\u5468\u4e00\u6b21\uff0c\u6301\u7eed\u516d\u4e2a\u6708\u6216\u4e09\u4e2a\u6708\u5de6\u53f3\uff0c\u7136\u540e\u4e0b\u4e00\u9636\u6bb5\u6bcf\u6708\u4e00\u6b21\u3002\u6cbb\u7597\u65f6\u95f4\u957f\u77ed\u53d6\u51b3\u4e8e\u5177\u4f53\u60c5\u51b5\u3002<\/mark><\/p>\n<p class=\"wp-block-paragraph\">\n<p class=\"wp-block-paragraph\"><strong>7<\/strong> <strong>\u9ad8\u6d53\u5ea6\u7ef4\u751f\u7d20C\u6ef4<\/strong><strong>\u6ce8\u7597\u6cd5\u7684\u526f\u4f5c\u7528<\/strong>: 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