{"id":67439,"date":"2026-08-20T07:56:15","date_gmt":"2026-08-20T07:56:15","guid":{"rendered":"http:\/\/zydq.1006ss.com\/?p=67439"},"modified":"2026-08-20T07:56:15","modified_gmt":"2026-08-20T07:56:15","slug":"2020%e5%b9%b4%e4%b8%ad%e5%9b%bd%e5%ae%89%e5%be%bd%e6%84%9f%e6%9f%93%e4%b8%8e%e5%85%8d%e7%96%ab%e9%87%8d%e7%82%b9%e5%ae%9e%e9%aa%8c%e5%ae%a4%e7%9a%84%e5%9b%a2%e9%98%9f%e5%9c%a8%e3%80%8apharmacological","status":"publish","type":"post","link":"http:\/\/zydq.1006ss.com\/?p=67439","title":{"rendered":"2020\u5e74\u4e2d\u56fd\u5b89\u5fbd\u611f\u67d3\u4e0e\u514d\u75ab\u91cd\u70b9\u5b9e\u9a8c\u5ba4\u7684\u56e2\u961f\u5728\u300aPharmacological Research\u300b\uff08\u836f\u7406\u5b66\u7814\u7a76\uff09\u671f\u520a\u4e0a\u6b63\u5f0f\u53d1\u8868\u6587\u7ae0\u300aIvermectin, a potential anticancer drug derived from an antiparasitic drug\u300b\uff08\u300a\u4f0a\u7ef4\u83cc\u7d20\uff1a\u4e00\u79cd\u6e90\u81ea\u6297\u5bc4\u751f\u866b\u836f\u7269\u7684\u6f5c\u5728\u6297\u764c\u836f\u7269\u300b\uff09\u3002"},"content":{"rendered":"<p class=\"wp-block-paragraph\">2020\u5e74\u4e2d\u56fd\u5b89\u5fbd\u611f\u67d3\u4e0e\u514d\u75ab\u91cd\u70b9\u5b9e\u9a8c\u5ba4\u7684\u56e2\u961f\u5728\u300aPharmacological Research\u300b\uff08\u836f\u7406\u5b66\u7814\u7a76\uff09\u671f\u520a\u4e0a\u6b63\u5f0f\u53d1\u8868\u4e86\u4e00\u7bc7\u6587\u7ae0\uff0c\u540d\u4e3a\u300aIvermectin, a potential anticancer drug derived from an antiparasitic drug\u300b\uff08\u300a\u4f0a\u7ef4\u83cc\u7d20\uff1a\u4e00\u79cd\u6e90\u81ea\u6297\u5bc4\u751f\u866b\u836f\u7269\u7684\u6f5c\u5728\u6297\u764c\u836f\u7269\u300b\uff09\u3002<\/p>\n<p class=\"wp-block-paragraph\">\u4ed6\u4eec\u6839\u636e\u591a\u5e74\u7814\u7a76\u53d1\u73b0\uff0c\u4f0a\u7ef4\u83cc\u7d20\u5728\u975e\u6bd2\u6027\u5242\u91cf\u4e0b\u5bf9\u591a\u79cd\u764c\u7ec6\u80de\u5177\u6709\u663e\u8457\u6297\u764c\u4f5c\u7528\uff1a\u6291\u5236\u589e\u6b96\u3001\u8f6c\u79fb\u548c\u8840\u7ba1\u751f\u6210\uff0c\u4fc3\u8fdb\u7a0b\u5e8f\u6027\u7ec6\u80de\u6b7b\u4ea1\uff08\u51cb\u4ea1\u3001\u81ea\u566c\u3001\u7126\u4ea1\uff09\uff0c\u540c\u65f6\u6291\u5236\u80bf\u7624\u5e72\u7ec6\u80de\u3001\u9006\u8f6c\u591a\u836f\u8010\u836f\uff08MDR\uff09\uff0c\u5e76\u4e0e\u591a\u79cd\u5316\u7597\/\u9776\u5411\u836f\u7269\u534f\u540c\u589e\u6548\u3002<\/p>\n<p class=\"wp-block-paragraph\">\u8fd9\u7bc7\u6587\u7ae0\u5217\u51fa\u4e86 \u4f0a\u7ef4\u83cc\u7d20 \u5728\u4e0d\u540c\u764c\u75c7\u4e2d\u7684\u4f5c\u7528\uff1a<\/p>\n<p class=\"wp-block-paragraph\">\u4e73\u817a\u764c\uff08\u5305\u62ec\u4e09\u9634\u6027\u4e73\u817a\u764c TNBC\uff09\uff1a\u6291\u5236Akt\/mTOR \u8bf1\u5bfc\u81ea\u566c\uff1b\u6062\u590d\u4ed6\u5bf9\u83ab\u6614\u82ac\u654f\u611f\u6027\uff1b\u901a\u8fc7P2X4\/P2X7\/Pannexin-1 \u91ca\u653eHMGB1 \u8bf1\u5bfc\u514d\u75ab\u539f\u6027\u7ec6\u80de\u6b7b\u4ea1\u3002<\/p>\n<p class=\"wp-block-paragraph\">\u6d88\u5316\u7cfb\u7edf\u764c\uff1a\u80c3\u764c\uff08YAP1 \u4f9d\u8d56\uff09\u3001\u7ed3\u76f4\u80a0\u764c\uff08\u963b\u65adWnt \u901a\u8def\uff09\u3001\u809d\u7ec6\u80de\u764c\uff08\u963b\u65adYAP1\uff09\u3001\u80c6\u7ba1\u764c\uff08\u5bf9\u5409\u897f\u4ed6\u6ee8\u8010\u836f\u7ec6\u80de\u654f\u611f\uff09\u3002<\/p>\n<p class=\"wp-block-paragraph\">\u6ccc\u5c3f\u7cfb\u7edf\u764c\uff1a\u80be\u7ec6\u80de\u764c\uff08\u7ebf\u7c92\u4f53\u529f\u80fd\u969c\u788d\uff09\u3001\u524d\u5217\u817a\u764c\uff08\u589e\u5f3a\u6069\u6742\u9c81\u80fa\u3001\u9006\u8f6c\u591a\u897f\u4ed6\u8d5b\u8010\u836f\uff09\u3002<\/p>\n<p class=\"wp-block-paragraph\">\u8840\u6db2\u7cfb\u7edf\u764c\uff1a\u767d\u8840\u75c5\uff08\u6c2f\u79bb\u5b50\u5185\u6d41\u2192ROS\u2192\u7ebf\u7c92\u4f53\u635f\u4f24\uff0c\u5bf9\u6b63\u5e38\u9020\u8840\u7ec6\u80de\u9009\u62e9\u6027\u6740\u4f24\uff1b\u4e0e\u963f\u7cd6\u80de\u82f7\u3001\u67d4\u7ea2\u9709\u7d20\u534f\u540c\uff09\u3002<\/p>\n<p class=\"wp-block-paragraph\">\u751f\u6b96\u7cfb\u7edf\u764c\uff1a\u5bab\u9888\u764c\uff08G1\/S \u963b\u6ede\uff09\u3001\u5375\u5de2\u764c\uff08PAK1 \u6291\u5236\uff1b\u4e0e\u7d2b\u6749\u9187\u3001\u987a\u94c2\u534f\u540c\uff0c\u51e0\u4e4e\u5b8c\u5168\u6291\u5236\u80bf\u7624\u751f\u957f\uff09\u3002<\/p>\n<p class=\"wp-block-paragraph\">\u8111\u80f6\u8d28\u7624\uff1aU87\u3001U251 \u7b49\uff08Akt\/mTOR \u6291\u5236\u3001\u7ebf\u7c92\u4f53\u635f\u4f24\u3001\u6291\u5236\u8840\u7ba1\u751f\u6210\uff09\uff1b\u4f46\u56e0\u96be\u4ee5\u901a\u8fc7\u8840\u8111\u5c4f\u969c\uff0c\u5e94\u7528\u524d\u666f\u53d7\u9650\u3002<\/p>\n<p class=\"wp-block-paragraph\">\u547c\u5438\u7cfb\u7edf\u764c\uff1a\u9f3b\u54bd\u764c\uff08PAK1-MAPK\uff09\u3001\u80ba\u764c\uff08YAP1 \u6291\u5236\u3001EMT \u6291\u5236\uff1b\u4e0e\u5384\u6d1b\u66ff\u5c3c\u534f\u540c\uff09\u3002<\/p>\n<p class=\"wp-block-paragraph\">\u9ed1\u8272\u7d20\u7624\uff1aBRAF \u7a81\u53d8\/\u91ce\u751f\u578b\u5747\u6709\u6548\uff08PAK1 \u9776\u70b9\u3001TFE3 \u6838\u8f6c\u4f4d\u8bf1\u5bfc\u81ea\u566c\uff1b\u4e0e\u8fbe\u62c9\u83f2\u5c3c\u534f\u540c\uff1b\u6291\u5236\u80ba\u8f6c\u79fb\uff09\u3002<\/p>\n<p class=\"wp-block-paragraph\">VM \u53ef\u8bf1\u5bfc\u6df7\u5408\u578b\u7ec6\u80de\u6b7b\u4ea1\u3001\u81ea\u566c\u3001\u6291\u5236\u80bf\u7624\u5e72\u7ec6\u80de\u3001\u9006\u8f6c\u591a\u836f\u8010\u836f\u7b49\u7b49\u6297\u764c\u6548\u679c\u3002<\/p>\n<p class=\"wp-block-paragraph\">\n<h1 class=\"wp-block-heading\">\u4f0a\u7ef4\u83cc\u7d20\u662f\u4e00\u79cd\u6f5c\u5728\u7684\u6297\u764c\u836f\u7269\uff0c\u6e90\u81ea\u4e00\u79cd\u6297\u5bc4\u751f\u866b\u836f\u7269\u3002<\/h1>\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32971268\/\">\u539f\u6587\u94fe\u63a5<\/a> 2020\u5e749\u670821\u65e5\u53d1\u5e03\u3002<\/p>\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Tang+M&amp;cauthor_id=32971268\">\u5510\u660e\u9633<\/a><sup>&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32971268\/#full-view-affiliation-1\">1<\/a><\/sup>\uff0c&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Hu+X&amp;cauthor_id=32971268\">\u80e1\u6653\u4e1c<\/a><sup>&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32971268\/#full-view-affiliation-2\">2<\/a><\/sup>\uff0c&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Wang+Y&amp;cauthor_id=32971268\">\u738b\u6bc5<\/a><sup>&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32971268\/#full-view-affiliation-3\">3<\/a><\/sup>\uff0c&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Yao+X&amp;cauthor_id=32971268\">\u946b\u8000<\/a><sup>&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32971268\/#full-view-affiliation-4\">4<\/a><\/sup>\uff0c&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Zhang+W&amp;cauthor_id=32971268\">\u5f20\u4f1f<\/a><sup>&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32971268\/#full-view-affiliation-5\">5<\/a><\/sup>\uff0c&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Yu+C&amp;cauthor_id=32971268\">\u4e8e\u6668\u82f1<\/a><sup>&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32971268\/#full-view-affiliation-6\">6<\/a><\/sup>\uff0c&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Cheng+F&amp;cauthor_id=32971268\">\u7a0b\u798f\u82f1<\/a><sup>&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32971268\/#full-view-affiliation-7\">7<\/a><\/sup>\uff0c&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Li+J&amp;cauthor_id=32971268\">\u674e\u6c5f\u8273<\/a><sup>&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32971268\/#full-view-affiliation-8\">8<\/a><\/sup>\uff0c&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Fang+Q&amp;cauthor_id=32971268\">\u65b9\u5f3a<\/a><sup>&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32971268\/#full-view-affiliation-9\">9<\/a><\/sup>\u96b6\u5c5e\u5173\u7cfb&nbsp;\u6269\u5f20<\/p>\n<ul id=\"full-view-identifiers\" class=\"wp-block-list\">\n<li>PMID\uff1a&nbsp;<strong>32971268<\/strong><\/li>\n<li>PMCID\uff1a&nbsp;<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC7505114\/\" target=\"_blank\" rel=\"noreferrer noopener\">PMC7505114<\/a><\/li>\n<li>DOI\uff1a&nbsp;<a href=\"https:\/\/doi.org\/10.1016\/j.phrs.2020.105207\" target=\"_blank\" rel=\"noreferrer noopener\">10.1016\/j.phrs.2020.105207<\/a><\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">\u6458\u8981<\/h2>\n<p class=\"wp-block-paragraph\">\u4f0a\u7ef4\u83cc\u7d20\u662f\u4e00\u79cd\u542b\u670916\u5143\u73af\u7684\u5927\u73af\u5185\u916f\u7c7b\u6297\u5bc4\u751f\u866b\u836f\u7269\uff0c\u5e7f\u6cdb\u7528\u4e8e\u6cbb\u7597\u591a\u79cd\u5bc4\u751f\u866b\u75c5\uff0c\u4f8b\u5982\u6cb3\u76f2\u75c7\u3001\u8c61\u76ae\u75c5\u548c\u75a5\u75ae\u3002\u5927\u6751\u806a\u548c\u5a01\u5ec9\u00b7C\u00b7\u574e\u8d1d\u5c14\u56e0\u53d1\u73b0\u4f0a\u7ef4\u83cc\u7d20\u5bf9\u5bc4\u751f\u866b\u75c5\u5177\u6709\u5353\u8d8a\u7684\u7597\u6548\u800c\u8363\u83b72015\u5e74\u8bfa\u8d1d\u5c14\u751f\u7406\u5b66\u6216\u533b\u5b66\u5956\u3002\u8fd1\u671f\u7814\u7a76\u8868\u660e\uff0c\u4f0a\u7ef4\u83cc\u7d20\u53ef\u901a\u8fc7\u8c03\u8282\u591a\u79cd\u4fe1\u53f7\u901a\u8def\u6291\u5236\u591a\u79cd\u80bf\u7624\u7ec6\u80de\u7684\u589e\u6b96\u3002\u8fd9\u63d0\u793a\u4f0a\u7ef4\u83cc\u7d20\u53ef\u80fd\u662f\u4e00\u79cd\u5177\u6709\u5de8\u5927\u6f5c\u529b\u7684\u6297\u764c\u836f\u7269\u3002\u672c\u6587\u7efc\u8ff0\u4e86\u4f0a\u7ef4\u83cc\u7d20\u6291\u5236\u4e0d\u540c\u764c\u75c7\u53d1\u5c55\u548c\u4fc3\u8fdb\u7a0b\u5e8f\u6027\u7ec6\u80de\u6b7b\u4ea1\u7684\u76f8\u5173\u673a\u5236\uff0c\u5e76\u63a2\u8ba8\u4e86\u4f0a\u7ef4\u83cc\u7d20\u4f5c\u4e3a\u6297\u764c\u836f\u7269\u5728\u80bf\u7624\u6cbb\u7597\u4e2d\u7684\u4e34\u5e8a\u5e94\u7528\u524d\u666f\u3002<\/p>\n<p class=\"wp-block-paragraph\"><strong>\u5173\u952e\u8bcd\uff1a&nbsp;<\/strong>\u963f\u7ef4\u83cc\u7d20\uff08PubChem CID\uff1a6434889\uff09\uff1b\u764c\u75c7\uff1b\u591a\u62c9\u83cc\u7d20\uff08PubChem CID\uff1a9832750\uff09\uff1b\u836f\u7269\u91cd\u5b9a\u4f4d\uff1b\u4f0a\u7ef4\u83cc\u7d20\uff1b\u4f0a\u7ef4\u83cc\u7d20\uff08PubChem CID\uff1a6321424\uff09\uff1b\u83ab\u6614\u83cc\u7d20\uff08PubChem CID\uff1a9832912\uff09\uff1b\u585e\u62c9\u83cc\u7d20\uff08PubChem CID\uff1a9578507\uff09\u3002<\/p>\n<p class=\"wp-block-paragraph\" id=\"copyright\">\u7248\u6743\u6240\u6709 \u00a9 2020 Elsevier Ltd. \u4fdd\u7559\u6240\u6709\u6743\u5229\u3002<\/p>\n<p class=\"wp-block-paragraph\" id=\"disclaimer\">\n<h2 class=\"wp-block-heading\">\u5229\u76ca\u51b2\u7a81\u58f0\u660e<\/h2>\n<p class=\"wp-block-paragraph\">\u4f5c\u8005\u58f0\u660e\u65e0\u5229\u76ca\u51b2\u7a81\u3002<\/p>\n<h2 class=\"wp-block-heading\">\u6570\u636e<\/h2>\n<figure class=\"wp-block-image\"><a class=\"figure-link\" href=\"https:\/\/cdn.ncbi.nlm.nih.gov\/pmc\/blobs\/a0ac\/7505114\/36f67c3f4434\/ga1_lrg.jpg\" data-lightbox=\"image_lg\"><img title=\"2020\u5e74\u4e2d\u56fd\u5b89\u5fbd\u611f\u67d3\u4e0e\u514d\u75ab\u91cd\u70b9\u5b9e\u9a8c\u5ba4\u7684\u56e2\u961f\u5728\u300aPharmacological Research\u300b\uff08\u836f\u7406\u5b66\u7814\u7a76\uff09\u671f\u520a\u4e0a\u6b63\u5f0f\u53d1\u8868\u6587\u7ae0\u300aIvermectin, a potential anticancer drug derived from an antiparasitic drug\u300b\uff08\u300a\u4f0a\u7ef4\u83cc\u7d20\uff1a\u4e00\u79cd\u6e90\u81ea\u6297\u5bc4\u751f\u866b\u836f\u7269\u7684\u6f5c\u5728\u6297\u764c\u836f\u7269\u300b\uff09\u3002 - \u7b2c1\u5f20  | \u4e2d\u836f\u517b\u751f\u77e5\u8bc6-\u4e2d\u8349\u836f\u7684\u529f\u6548\u4e0e\u4f5c\u7528\" alt=\"2020\u5e74\u4e2d\u56fd\u5b89\u5fbd\u611f\u67d3\u4e0e\u514d\u75ab\u91cd\u70b9\u5b9e\u9a8c\u5ba4\u7684\u56e2\u961f\u5728\u300aPharmacological Research\u300b\uff08\u836f\u7406\u5b66\u7814\u7a76\uff09\u671f\u520a\u4e0a\u6b63\u5f0f\u53d1\u8868\u6587\u7ae0\u300aIvermectin, a potential anticancer drug derived from an antiparasitic drug\u300b\uff08\u300a\u4f0a\u7ef4\u83cc\u7d20\uff1a\u4e00\u79cd\u6e90\u81ea\u6297\u5bc4\u751f\u866b\u836f\u7269\u7684\u6f5c\u5728\u6297\u764c\u836f\u7269\u300b\uff09\u3002 - \u7b2c1\u5f20  | \u4e2d\u836f\u517b\u751f\u77e5\u8bc6-\u4e2d\u8349\u836f\u7684\u529f\u6548\u4e0e\u4f5c\u7528\"  data-perfmatters-preload  data-src=\"https:\/\/cdn.ncbi.nlm.nih.gov\/pmc\/blobs\/a0ac\/7505114\/00ed73947ea8\/ga1_lrg.gif\" \/><\/a><\/figure>\n<p class=\"wp-block-paragraph\">\u56fe\u6587\u6458\u8981<\/p>\n<p class=\"wp-block-paragraph\">\n<figure class=\"wp-block-image\"><a class=\"figure-link\" href=\"https:\/\/cdn.ncbi.nlm.nih.gov\/pmc\/blobs\/a0ac\/7505114\/cab285e6858a\/gr1_lrg.jpg\" data-lightbox=\"image_lg\"><img title=\"2020\u5e74\u4e2d\u56fd\u5b89\u5fbd\u611f\u67d3\u4e0e\u514d\u75ab\u91cd\u70b9\u5b9e\u9a8c\u5ba4\u7684\u56e2\u961f\u5728\u300aPharmacological Research\u300b\uff08\u836f\u7406\u5b66\u7814\u7a76\uff09\u671f\u520a\u4e0a\u6b63\u5f0f\u53d1\u8868\u6587\u7ae0\u300aIvermectin, a potential anticancer drug derived from an antiparasitic drug\u300b\uff08\u300a\u4f0a\u7ef4\u83cc\u7d20\uff1a\u4e00\u79cd\u6e90\u81ea\u6297\u5bc4\u751f\u866b\u836f\u7269\u7684\u6f5c\u5728\u6297\u764c\u836f\u7269\u300b\uff09\u3002 - \u7b2c2\u5f20  | \u4e2d\u836f\u517b\u751f\u77e5\u8bc6-\u4e2d\u8349\u836f\u7684\u529f\u6548\u4e0e\u4f5c\u7528\" alt=\"2020\u5e74\u4e2d\u56fd\u5b89\u5fbd\u611f\u67d3\u4e0e\u514d\u75ab\u91cd\u70b9\u5b9e\u9a8c\u5ba4\u7684\u56e2\u961f\u5728\u300aPharmacological Research\u300b\uff08\u836f\u7406\u5b66\u7814\u7a76\uff09\u671f\u520a\u4e0a\u6b63\u5f0f\u53d1\u8868\u6587\u7ae0\u300aIvermectin, a potential anticancer drug derived from an antiparasitic drug\u300b\uff08\u300a\u4f0a\u7ef4\u83cc\u7d20\uff1a\u4e00\u79cd\u6e90\u81ea\u6297\u5bc4\u751f\u866b\u836f\u7269\u7684\u6f5c\u5728\u6297\u764c\u836f\u7269\u300b\uff09\u3002 - \u7b2c2\u5f20  | \u4e2d\u836f\u517b\u751f\u77e5\u8bc6-\u4e2d\u8349\u836f\u7684\u529f\u6548\u4e0e\u4f5c\u7528\"   data-src=\"\/\/www.w3.org\/2000\/svg&#039;%20width=&#039;0&#039;%20height=&#039;0&#039;%20viewBox=&#039;0%200%200%200&#039;%3E%3C\/svg%3E\" class=\"perfmatters-lazy\" data-src=\"https:\/\/cdn.ncbi.nlm.nih.gov\/pmc\/blobs\/a0ac\/7505114\/5eabceefdc42\/gr1_lrg.gif\" \/><img decoding=\"async\" title=\"2020\u5e74\u4e2d\u56fd\u5b89\u5fbd\u611f\u67d3\u4e0e\u514d\u75ab\u91cd\u70b9\u5b9e\u9a8c\u5ba4\u7684\u56e2\u961f\u5728\u300aPharmacological Research\u300b\uff08\u836f\u7406\u5b66\u7814\u7a76\uff09\u671f\u520a\u4e0a\u6b63\u5f0f\u53d1\u8868\u6587\u7ae0\u300aIvermectin, a potential anticancer drug derived from an antiparasitic drug\u300b\uff08\u300a\u4f0a\u7ef4\u83cc\u7d20\uff1a\u4e00\u79cd\u6e90\u81ea\u6297\u5bc4\u751f\u866b\u836f\u7269\u7684\u6f5c\u5728\u6297\u764c\u836f\u7269\u300b\uff09\u3002 - \u7b2c3\u5f20  | \u4e2d\u836f\u517b\u751f\u77e5\u8bc6-\u4e2d\u8349\u836f\u7684\u529f\u6548\u4e0e\u4f5c\u7528\" alt=\"2020\u5e74\u4e2d\u56fd\u5b89\u5fbd\u611f\u67d3\u4e0e\u514d\u75ab\u91cd\u70b9\u5b9e\u9a8c\u5ba4\u7684\u56e2\u961f\u5728\u300aPharmacological Research\u300b\uff08\u836f\u7406\u5b66\u7814\u7a76\uff09\u671f\u520a\u4e0a\u6b63\u5f0f\u53d1\u8868\u6587\u7ae0\u300aIvermectin, a potential anticancer drug derived from an antiparasitic drug\u300b\uff08\u300a\u4f0a\u7ef4\u83cc\u7d20\uff1a\u4e00\u79cd\u6e90\u81ea\u6297\u5bc4\u751f\u866b\u836f\u7269\u7684\u6f5c\u5728\u6297\u764c\u836f\u7269\u300b\uff09\u3002 - \u7b2c3\u5f20  | \u4e2d\u836f\u517b\u751f\u77e5\u8bc6-\u4e2d\u8349\u836f\u7684\u529f\u6548\u4e0e\u4f5c\u7528\" src=\"https:\/\/cdn.ncbi.nlm.nih.gov\/pmc\/blobs\/a0ac\/7505114\/5eabceefdc42\/gr1_lrg.gif\" \/><\/a><\/figure>\n<p class=\"wp-block-paragraph\">\u56fe 1 \u4f0a\u7ef4\u83cc\u7d20\u7684\u5316\u5b66\u7ed3\u6784\u2026\u2026<\/p>\n<p class=\"wp-block-paragraph\">\n<figure class=\"wp-block-image\"><a class=\"figure-link\" href=\"https:\/\/cdn.ncbi.nlm.nih.gov\/pmc\/blobs\/a0ac\/7505114\/f39f6fd610c5\/gr2_lrg.jpg\" data-lightbox=\"image_lg\"><img title=\"2020\u5e74\u4e2d\u56fd\u5b89\u5fbd\u611f\u67d3\u4e0e\u514d\u75ab\u91cd\u70b9\u5b9e\u9a8c\u5ba4\u7684\u56e2\u961f\u5728\u300aPharmacological Research\u300b\uff08\u836f\u7406\u5b66\u7814\u7a76\uff09\u671f\u520a\u4e0a\u6b63\u5f0f\u53d1\u8868\u6587\u7ae0\u300aIvermectin, a potential anticancer drug derived from an antiparasitic drug\u300b\uff08\u300a\u4f0a\u7ef4\u83cc\u7d20\uff1a\u4e00\u79cd\u6e90\u81ea\u6297\u5bc4\u751f\u866b\u836f\u7269\u7684\u6f5c\u5728\u6297\u764c\u836f\u7269\u300b\uff09\u3002 - \u7b2c4\u5f20  | \u4e2d\u836f\u517b\u751f\u77e5\u8bc6-\u4e2d\u8349\u836f\u7684\u529f\u6548\u4e0e\u4f5c\u7528\" alt=\"2020\u5e74\u4e2d\u56fd\u5b89\u5fbd\u611f\u67d3\u4e0e\u514d\u75ab\u91cd\u70b9\u5b9e\u9a8c\u5ba4\u7684\u56e2\u961f\u5728\u300aPharmacological Research\u300b\uff08\u836f\u7406\u5b66\u7814\u7a76\uff09\u671f\u520a\u4e0a\u6b63\u5f0f\u53d1\u8868\u6587\u7ae0\u300aIvermectin, a potential anticancer drug derived from an antiparasitic drug\u300b\uff08\u300a\u4f0a\u7ef4\u83cc\u7d20\uff1a\u4e00\u79cd\u6e90\u81ea\u6297\u5bc4\u751f\u866b\u836f\u7269\u7684\u6f5c\u5728\u6297\u764c\u836f\u7269\u300b\uff09\u3002 - \u7b2c4\u5f20  | \u4e2d\u836f\u517b\u751f\u77e5\u8bc6-\u4e2d\u8349\u836f\u7684\u529f\u6548\u4e0e\u4f5c\u7528\"   data-src=\"\/\/www.w3.org\/2000\/svg&#039;%20width=&#039;0&#039;%20height=&#039;0&#039;%20viewBox=&#039;0%200%200%200&#039;%3E%3C\/svg%3E\" class=\"perfmatters-lazy\" data-src=\"https:\/\/cdn.ncbi.nlm.nih.gov\/pmc\/blobs\/a0ac\/7505114\/d74cd016581a\/gr2_lrg.gif\" \/><img decoding=\"async\" title=\"2020\u5e74\u4e2d\u56fd\u5b89\u5fbd\u611f\u67d3\u4e0e\u514d\u75ab\u91cd\u70b9\u5b9e\u9a8c\u5ba4\u7684\u56e2\u961f\u5728\u300aPharmacological Research\u300b\uff08\u836f\u7406\u5b66\u7814\u7a76\uff09\u671f\u520a\u4e0a\u6b63\u5f0f\u53d1\u8868\u6587\u7ae0\u300aIvermectin, a potential anticancer drug derived from an antiparasitic drug\u300b\uff08\u300a\u4f0a\u7ef4\u83cc\u7d20\uff1a\u4e00\u79cd\u6e90\u81ea\u6297\u5bc4\u751f\u866b\u836f\u7269\u7684\u6f5c\u5728\u6297\u764c\u836f\u7269\u300b\uff09\u3002 - \u7b2c5\u5f20  | \u4e2d\u836f\u517b\u751f\u77e5\u8bc6-\u4e2d\u8349\u836f\u7684\u529f\u6548\u4e0e\u4f5c\u7528\" alt=\"2020\u5e74\u4e2d\u56fd\u5b89\u5fbd\u611f\u67d3\u4e0e\u514d\u75ab\u91cd\u70b9\u5b9e\u9a8c\u5ba4\u7684\u56e2\u961f\u5728\u300aPharmacological Research\u300b\uff08\u836f\u7406\u5b66\u7814\u7a76\uff09\u671f\u520a\u4e0a\u6b63\u5f0f\u53d1\u8868\u6587\u7ae0\u300aIvermectin, a potential anticancer drug derived from an antiparasitic drug\u300b\uff08\u300a\u4f0a\u7ef4\u83cc\u7d20\uff1a\u4e00\u79cd\u6e90\u81ea\u6297\u5bc4\u751f\u866b\u836f\u7269\u7684\u6f5c\u5728\u6297\u764c\u836f\u7269\u300b\uff09\u3002 - \u7b2c5\u5f20  | \u4e2d\u836f\u517b\u751f\u77e5\u8bc6-\u4e2d\u8349\u836f\u7684\u529f\u6548\u4e0e\u4f5c\u7528\" src=\"https:\/\/cdn.ncbi.nlm.nih.gov\/pmc\/blobs\/a0ac\/7505114\/d74cd016581a\/gr2_lrg.gif\" \/><\/a><\/figure>\n<p class=\"wp-block-paragraph\">\u56fe 2 \u4f0a\u7ef4\u83cc\u7d20\u8bf1\u5bfc\u7ebf\u7c92\u4f53\u4ecb\u5bfc\u7ec6\u80de\u51cb\u4ea1\u7684\u673a\u5236\u2026\u2026<\/p>\n<p class=\"wp-block-paragraph\">\n<figure class=\"wp-block-image\"><a class=\"figure-link\" href=\"https:\/\/cdn.ncbi.nlm.nih.gov\/pmc\/blobs\/a0ac\/7505114\/2319e472e106\/gr3_lrg.jpg\" data-lightbox=\"image_lg\"><img title=\"2020\u5e74\u4e2d\u56fd\u5b89\u5fbd\u611f\u67d3\u4e0e\u514d\u75ab\u91cd\u70b9\u5b9e\u9a8c\u5ba4\u7684\u56e2\u961f\u5728\u300aPharmacological Research\u300b\uff08\u836f\u7406\u5b66\u7814\u7a76\uff09\u671f\u520a\u4e0a\u6b63\u5f0f\u53d1\u8868\u6587\u7ae0\u300aIvermectin, a potential anticancer drug derived from an antiparasitic drug\u300b\uff08\u300a\u4f0a\u7ef4\u83cc\u7d20\uff1a\u4e00\u79cd\u6e90\u81ea\u6297\u5bc4\u751f\u866b\u836f\u7269\u7684\u6f5c\u5728\u6297\u764c\u836f\u7269\u300b\uff09\u3002 - \u7b2c6\u5f20  | \u4e2d\u836f\u517b\u751f\u77e5\u8bc6-\u4e2d\u8349\u836f\u7684\u529f\u6548\u4e0e\u4f5c\u7528\" alt=\"2020\u5e74\u4e2d\u56fd\u5b89\u5fbd\u611f\u67d3\u4e0e\u514d\u75ab\u91cd\u70b9\u5b9e\u9a8c\u5ba4\u7684\u56e2\u961f\u5728\u300aPharmacological Research\u300b\uff08\u836f\u7406\u5b66\u7814\u7a76\uff09\u671f\u520a\u4e0a\u6b63\u5f0f\u53d1\u8868\u6587\u7ae0\u300aIvermectin, a potential anticancer drug derived from an antiparasitic drug\u300b\uff08\u300a\u4f0a\u7ef4\u83cc\u7d20\uff1a\u4e00\u79cd\u6e90\u81ea\u6297\u5bc4\u751f\u866b\u836f\u7269\u7684\u6f5c\u5728\u6297\u764c\u836f\u7269\u300b\uff09\u3002 - \u7b2c6\u5f20  | \u4e2d\u836f\u517b\u751f\u77e5\u8bc6-\u4e2d\u8349\u836f\u7684\u529f\u6548\u4e0e\u4f5c\u7528\"   data-src=\"\/\/www.w3.org\/2000\/svg&#039;%20width=&#039;0&#039;%20height=&#039;0&#039;%20viewBox=&#039;0%200%200%200&#039;%3E%3C\/svg%3E\" class=\"perfmatters-lazy\" data-src=\"https:\/\/cdn.ncbi.nlm.nih.gov\/pmc\/blobs\/a0ac\/7505114\/98e42f64ef08\/gr3_lrg.gif\" \/><img decoding=\"async\" title=\"2020\u5e74\u4e2d\u56fd\u5b89\u5fbd\u611f\u67d3\u4e0e\u514d\u75ab\u91cd\u70b9\u5b9e\u9a8c\u5ba4\u7684\u56e2\u961f\u5728\u300aPharmacological Research\u300b\uff08\u836f\u7406\u5b66\u7814\u7a76\uff09\u671f\u520a\u4e0a\u6b63\u5f0f\u53d1\u8868\u6587\u7ae0\u300aIvermectin, a potential anticancer drug derived from an antiparasitic drug\u300b\uff08\u300a\u4f0a\u7ef4\u83cc\u7d20\uff1a\u4e00\u79cd\u6e90\u81ea\u6297\u5bc4\u751f\u866b\u836f\u7269\u7684\u6f5c\u5728\u6297\u764c\u836f\u7269\u300b\uff09\u3002 - \u7b2c7\u5f20  | \u4e2d\u836f\u517b\u751f\u77e5\u8bc6-\u4e2d\u8349\u836f\u7684\u529f\u6548\u4e0e\u4f5c\u7528\" alt=\"2020\u5e74\u4e2d\u56fd\u5b89\u5fbd\u611f\u67d3\u4e0e\u514d\u75ab\u91cd\u70b9\u5b9e\u9a8c\u5ba4\u7684\u56e2\u961f\u5728\u300aPharmacological Research\u300b\uff08\u836f\u7406\u5b66\u7814\u7a76\uff09\u671f\u520a\u4e0a\u6b63\u5f0f\u53d1\u8868\u6587\u7ae0\u300aIvermectin, a potential anticancer drug derived from an antiparasitic drug\u300b\uff08\u300a\u4f0a\u7ef4\u83cc\u7d20\uff1a\u4e00\u79cd\u6e90\u81ea\u6297\u5bc4\u751f\u866b\u836f\u7269\u7684\u6f5c\u5728\u6297\u764c\u836f\u7269\u300b\uff09\u3002 - \u7b2c7\u5f20  | \u4e2d\u836f\u517b\u751f\u77e5\u8bc6-\u4e2d\u8349\u836f\u7684\u529f\u6548\u4e0e\u4f5c\u7528\" src=\"https:\/\/cdn.ncbi.nlm.nih.gov\/pmc\/blobs\/a0ac\/7505114\/98e42f64ef08\/gr3_lrg.gif\" \/><\/a><\/figure>\n<p class=\"wp-block-paragraph\">\u56fe 3 \u4f0a\u7ef4\u83cc\u7d20\u8bf1\u5bfc\u7684PAK1\/Akt\/mTOR\u4ecb\u5bfc\u7684\u81ea\u566c\u673a\u5236\u2026\u2026<\/p>\n<p class=\"wp-block-paragraph\">\n<figure class=\"wp-block-image\"><a class=\"figure-link\" href=\"https:\/\/cdn.ncbi.nlm.nih.gov\/pmc\/blobs\/a0ac\/7505114\/abfb5b9d4b2c\/gr4_lrg.jpg\" data-lightbox=\"image_lg\"><img title=\"2020\u5e74\u4e2d\u56fd\u5b89\u5fbd\u611f\u67d3\u4e0e\u514d\u75ab\u91cd\u70b9\u5b9e\u9a8c\u5ba4\u7684\u56e2\u961f\u5728\u300aPharmacological Research\u300b\uff08\u836f\u7406\u5b66\u7814\u7a76\uff09\u671f\u520a\u4e0a\u6b63\u5f0f\u53d1\u8868\u6587\u7ae0\u300aIvermectin, a potential anticancer drug derived from an antiparasitic drug\u300b\uff08\u300a\u4f0a\u7ef4\u83cc\u7d20\uff1a\u4e00\u79cd\u6e90\u81ea\u6297\u5bc4\u751f\u866b\u836f\u7269\u7684\u6f5c\u5728\u6297\u764c\u836f\u7269\u300b\uff09\u3002 - \u7b2c8\u5f20  | \u4e2d\u836f\u517b\u751f\u77e5\u8bc6-\u4e2d\u8349\u836f\u7684\u529f\u6548\u4e0e\u4f5c\u7528\" alt=\"2020\u5e74\u4e2d\u56fd\u5b89\u5fbd\u611f\u67d3\u4e0e\u514d\u75ab\u91cd\u70b9\u5b9e\u9a8c\u5ba4\u7684\u56e2\u961f\u5728\u300aPharmacological Research\u300b\uff08\u836f\u7406\u5b66\u7814\u7a76\uff09\u671f\u520a\u4e0a\u6b63\u5f0f\u53d1\u8868\u6587\u7ae0\u300aIvermectin, a potential anticancer drug derived from an antiparasitic drug\u300b\uff08\u300a\u4f0a\u7ef4\u83cc\u7d20\uff1a\u4e00\u79cd\u6e90\u81ea\u6297\u5bc4\u751f\u866b\u836f\u7269\u7684\u6f5c\u5728\u6297\u764c\u836f\u7269\u300b\uff09\u3002 - \u7b2c8\u5f20  | \u4e2d\u836f\u517b\u751f\u77e5\u8bc6-\u4e2d\u8349\u836f\u7684\u529f\u6548\u4e0e\u4f5c\u7528\"   data-src=\"\/\/www.w3.org\/2000\/svg&#039;%20width=&#039;0&#039;%20height=&#039;0&#039;%20viewBox=&#039;0%200%200%200&#039;%3E%3C\/svg%3E\" class=\"perfmatters-lazy\" data-src=\"https:\/\/cdn.ncbi.nlm.nih.gov\/pmc\/blobs\/a0ac\/7505114\/3ce846533f71\/gr4_lrg.gif\" \/><img decoding=\"async\" title=\"2020\u5e74\u4e2d\u56fd\u5b89\u5fbd\u611f\u67d3\u4e0e\u514d\u75ab\u91cd\u70b9\u5b9e\u9a8c\u5ba4\u7684\u56e2\u961f\u5728\u300aPharmacological Research\u300b\uff08\u836f\u7406\u5b66\u7814\u7a76\uff09\u671f\u520a\u4e0a\u6b63\u5f0f\u53d1\u8868\u6587\u7ae0\u300aIvermectin, a potential anticancer drug derived from an antiparasitic drug\u300b\uff08\u300a\u4f0a\u7ef4\u83cc\u7d20\uff1a\u4e00\u79cd\u6e90\u81ea\u6297\u5bc4\u751f\u866b\u836f\u7269\u7684\u6f5c\u5728\u6297\u764c\u836f\u7269\u300b\uff09\u3002 - \u7b2c9\u5f20  | \u4e2d\u836f\u517b\u751f\u77e5\u8bc6-\u4e2d\u8349\u836f\u7684\u529f\u6548\u4e0e\u4f5c\u7528\" alt=\"2020\u5e74\u4e2d\u56fd\u5b89\u5fbd\u611f\u67d3\u4e0e\u514d\u75ab\u91cd\u70b9\u5b9e\u9a8c\u5ba4\u7684\u56e2\u961f\u5728\u300aPharmacological Research\u300b\uff08\u836f\u7406\u5b66\u7814\u7a76\uff09\u671f\u520a\u4e0a\u6b63\u5f0f\u53d1\u8868\u6587\u7ae0\u300aIvermectin, a potential anticancer drug derived from an antiparasitic drug\u300b\uff08\u300a\u4f0a\u7ef4\u83cc\u7d20\uff1a\u4e00\u79cd\u6e90\u81ea\u6297\u5bc4\u751f\u866b\u836f\u7269\u7684\u6f5c\u5728\u6297\u764c\u836f\u7269\u300b\uff09\u3002 - \u7b2c9\u5f20  | \u4e2d\u836f\u517b\u751f\u77e5\u8bc6-\u4e2d\u8349\u836f\u7684\u529f\u6548\u4e0e\u4f5c\u7528\" src=\"https:\/\/cdn.ncbi.nlm.nih.gov\/pmc\/blobs\/a0ac\/7505114\/3ce846533f71\/gr4_lrg.gif\" \/><\/a><\/figure>\n<p class=\"wp-block-paragraph\">\u56fe 4 IVM\u8bf1\u5bfcP2\u00d7\u2026\u7684\u673a\u5236<\/p>\n<p class=\"wp-block-paragraph\">\n<figure class=\"wp-block-image\"><a class=\"figure-link\" href=\"https:\/\/cdn.ncbi.nlm.nih.gov\/pmc\/blobs\/a0ac\/7505114\/6a266d849067\/gr5_lrg.jpg\" data-lightbox=\"image_lg\"><img title=\"2020\u5e74\u4e2d\u56fd\u5b89\u5fbd\u611f\u67d3\u4e0e\u514d\u75ab\u91cd\u70b9\u5b9e\u9a8c\u5ba4\u7684\u56e2\u961f\u5728\u300aPharmacological Research\u300b\uff08\u836f\u7406\u5b66\u7814\u7a76\uff09\u671f\u520a\u4e0a\u6b63\u5f0f\u53d1\u8868\u6587\u7ae0\u300aIvermectin, a potential anticancer drug derived from an antiparasitic drug\u300b\uff08\u300a\u4f0a\u7ef4\u83cc\u7d20\uff1a\u4e00\u79cd\u6e90\u81ea\u6297\u5bc4\u751f\u866b\u836f\u7269\u7684\u6f5c\u5728\u6297\u764c\u836f\u7269\u300b\uff09\u3002 - \u7b2c10\u5f20  | \u4e2d\u836f\u517b\u751f\u77e5\u8bc6-\u4e2d\u8349\u836f\u7684\u529f\u6548\u4e0e\u4f5c\u7528\" alt=\"2020\u5e74\u4e2d\u56fd\u5b89\u5fbd\u611f\u67d3\u4e0e\u514d\u75ab\u91cd\u70b9\u5b9e\u9a8c\u5ba4\u7684\u56e2\u961f\u5728\u300aPharmacological Research\u300b\uff08\u836f\u7406\u5b66\u7814\u7a76\uff09\u671f\u520a\u4e0a\u6b63\u5f0f\u53d1\u8868\u6587\u7ae0\u300aIvermectin, a potential anticancer drug derived from an antiparasitic drug\u300b\uff08\u300a\u4f0a\u7ef4\u83cc\u7d20\uff1a\u4e00\u79cd\u6e90\u81ea\u6297\u5bc4\u751f\u866b\u836f\u7269\u7684\u6f5c\u5728\u6297\u764c\u836f\u7269\u300b\uff09\u3002 - \u7b2c10\u5f20  | \u4e2d\u836f\u517b\u751f\u77e5\u8bc6-\u4e2d\u8349\u836f\u7684\u529f\u6548\u4e0e\u4f5c\u7528\"   data-src=\"\/\/www.w3.org\/2000\/svg&#039;%20width=&#039;0&#039;%20height=&#039;0&#039;%20viewBox=&#039;0%200%200%200&#039;%3E%3C\/svg%3E\" class=\"perfmatters-lazy\" data-src=\"https:\/\/cdn.ncbi.nlm.nih.gov\/pmc\/blobs\/a0ac\/7505114\/9270c55047dd\/gr5_lrg.gif\" \/><img decoding=\"async\" title=\"2020\u5e74\u4e2d\u56fd\u5b89\u5fbd\u611f\u67d3\u4e0e\u514d\u75ab\u91cd\u70b9\u5b9e\u9a8c\u5ba4\u7684\u56e2\u961f\u5728\u300aPharmacological Research\u300b\uff08\u836f\u7406\u5b66\u7814\u7a76\uff09\u671f\u520a\u4e0a\u6b63\u5f0f\u53d1\u8868\u6587\u7ae0\u300aIvermectin, a potential anticancer drug derived from an antiparasitic drug\u300b\uff08\u300a\u4f0a\u7ef4\u83cc\u7d20\uff1a\u4e00\u79cd\u6e90\u81ea\u6297\u5bc4\u751f\u866b\u836f\u7269\u7684\u6f5c\u5728\u6297\u764c\u836f\u7269\u300b\uff09\u3002 - \u7b2c11\u5f20  | \u4e2d\u836f\u517b\u751f\u77e5\u8bc6-\u4e2d\u8349\u836f\u7684\u529f\u6548\u4e0e\u4f5c\u7528\" alt=\"2020\u5e74\u4e2d\u56fd\u5b89\u5fbd\u611f\u67d3\u4e0e\u514d\u75ab\u91cd\u70b9\u5b9e\u9a8c\u5ba4\u7684\u56e2\u961f\u5728\u300aPharmacological Research\u300b\uff08\u836f\u7406\u5b66\u7814\u7a76\uff09\u671f\u520a\u4e0a\u6b63\u5f0f\u53d1\u8868\u6587\u7ae0\u300aIvermectin, a potential anticancer drug derived from an antiparasitic drug\u300b\uff08\u300a\u4f0a\u7ef4\u83cc\u7d20\uff1a\u4e00\u79cd\u6e90\u81ea\u6297\u5bc4\u751f\u866b\u836f\u7269\u7684\u6f5c\u5728\u6297\u764c\u836f\u7269\u300b\uff09\u3002 - \u7b2c11\u5f20  | \u4e2d\u836f\u517b\u751f\u77e5\u8bc6-\u4e2d\u8349\u836f\u7684\u529f\u6548\u4e0e\u4f5c\u7528\" src=\"https:\/\/cdn.ncbi.nlm.nih.gov\/pmc\/blobs\/a0ac\/7505114\/9270c55047dd\/gr5_lrg.gif\" \/><\/a><\/figure>\n<p class=\"wp-block-paragraph\"><strong>\u56fe 5 PAK1 \u4ea4\u53c9\u8c03\u63a7\u591a\u79cd\u4fe1\u53f7\u901a\u8def\u2026\u2026<\/strong><\/p>\n<p class=\"wp-block-paragraph\">\n<h2 class=\"wp-block-heading\">\u76f8\u5173\u6587\u7ae0<\/h2>\n<ul id=\"similar-articles-list\" class=\"wp-block-list\">\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/20644115\/\">\u6297\u5bc4\u751f\u866b\u836f\u7269\u4f0a\u7ef4\u83cc\u7d20\u53ef\u8bf1\u5bfc\u767d\u8840\u75c5\u7ec6\u80de\u53d1\u751f\u6c2f\u79bb\u5b50\u4f9d\u8d56\u6027\u819c\u8d85\u6781\u5316\u548c\u7ec6\u80de\u6b7b\u4ea1\u3002<\/a>Sharmeen S\u3001Skrtic M\u3001Sukhai MA\u3001Hurren R\u3001Gronda M\u3001Wang X\u3001Fonseca SB\u3001Sun H\u3001Wood TE\u3001Ward R\u3001Minden MD\u3001Batey RA\u3001Datti A\u3001Wrana J\u3001Kelley SO\u3001Schimmer AD\u3002Blood. 2010 \u5e74 11 \u6708 4 \u65e5\uff1b116(18):3593-603\u3002doi\uff1a10.1182\/blood-2010-01-262675\u30022010 \u5e74 7 \u6708 19 \u65e5\u5728\u7ebf\u53d1\u8868\u3002PMID\uff1a20644115<\/li>\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26552892\/\">\u5bf9 2015 \u5e74\u8bfa\u8d1d\u5c14\u533b\u5b66\u5956\u7684\u53cd\u601d\u2014\u2014\u963f\u7ef4\u83cc\u7d20\u548c\u9752\u84bf\u7d20\u7684\u516c\u5171\u536b\u751f\u9057\u4ea7\u548c\u5f71\u54cd\u3002<\/a>Molyneux DH\uff0cWard SA\u3002Trends Parasitol. 2015 \u5e74 12 \u6708\uff1b31(12):605-607\u3002doi\uff1a10.1016\/j.pt.2015.10.008\u30022015 \u5e74 11 \u6708 6 \u65e5\u5728\u7ebf\u53d1\u8868\u3002PMID\uff1a26552892<\/li>\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37814994\/\">\u4f0a\u7ef4\u83cc\u7d20\u4f5c\u4e3a\u80f6\u8d28\u7624\u7684\u6f5c\u5728\u6cbb\u7597\u7b56\u7565\u3002<\/a>\u80e1X\u3001\u97a0Y\u3001\u5f20YK\u3002J Neurosci Res. 2024 \u5e74 1 \u6708\uff1b102(1):e25254\u3002doi\uff1a10.1002\/jnr.25254\u30022023 \u5e74 10 \u6708 10 \u65e5\u5728\u7ebf\u53d1\u8868\u3002PMID\uff1a37814994\u5ba1\u67e5\u3002<\/li>\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37793327\/\">\u4f0a\u7ef4\u83cc\u7d20\u7684\u6297\u5bc4\u751f\u866b\u6d3b\u6027\uff1a\u5bf9\u8fd9\u79cd\u201c\u795e\u5947\u836f\u7269\u201d\u957f\u8fbe\u56db\u5341\u5e74\u7684\u7814\u7a76\u3002<\/a>\u82cf\u91cc\u514b\u00b7M\u3001\u5b89\u6258\u4ec0\u624e\u514b\u00b7M\u3001\u80e1\u7434\u65af\u57fa\u00b7A\u3001\u53f2\u8482\u5f17\u4e01\u00b7D.\u6b27\u6d32\u533b\u5b66\u5316\u5b66\u6742\u5fd7\u3002 2023 \u5e74 12 \u6708 5 \u65e5\uff1b261:115838\u3002 doi\uff1a10.1016\/j.ejmech.2023.115838\u3002\u7535\u5b50\u7248 2023 \u5e74 9 \u6708 27 \u65e5\u3002PMID\uff1a37793327\u5ba1\u67e5\u3002<\/li>\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28196978\/\">\u4f0a\u7ef4\u83cc\u7d20\uff1a\u8fd9\u79cd\u795e\u79d8\u7684\u591a\u529f\u80fd\u201c\u795e\u5947\u201d\u836f\u7269\u4e0d\u65ad\u7ed9\u4eba\u5e26\u6765\u60ca\u559c\uff0c\u5e76\u8d85\u51fa\u9884\u671f\u3002<\/a>\u514b\u6717\u666e A.J Antibiot\uff08\u4e1c\u4eac\uff09\u3002 2017 \u5e74 5 \u6708\uff1b70(5):495-505\u3002 doi\uff1a10.1038\/ja.2017.11\u3002\u7535\u5b50\u7248 2017 \u5e74 2 \u6708 15 \u65e5\u3002PMID\uff1a28196978\u5ba1\u67e5\u3002<\/li>\n<\/ul>\n<p class=\"wp-block-paragraph\">\n<h2 class=\"wp-block-heading\">\u88ab\u5f15\u7528<\/h2>\n<ul id=\"citedby-articles-list\" class=\"wp-block-list\">\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38543218\/\">\u8f7d\u6709\u4f0a\u7ef4\u83cc\u7d20\u7684\u4ecb\u5b54\u4e8c\u6c27\u5316\u7845\u548c\u805a\u5408\u7269\u7eb3\u7c73\u80f6\u56ca\uff1a\u5bf9\u8f7d\u836f\u91cf\u3001\u4f53\u5916\u6eb6\u89e3\u5ea6\u589e\u5f3a\u548c\u91ca\u653e\u6027\u80fd\u7684\u5f71\u54cd\u3002<\/a>Velho MC\u3001Funk NL\u3001Deon M\u3001Benvenutti EV\u3001Buchner S\u3001Hinrichs R\u3001Pilger DA\u3001Beck RCR\u3002Pharmaceutics. 2024 \u5e74 2 \u6708 26 \u65e5\uff1b16(3):325\u3002doi\uff1a10.3390\/pharmaceutics16030325\u3002PMID\uff1a38543218\u514d\u8d39PMC\u6587\u7ae0\u3002<\/li>\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39411968\/\">\u591a\u62c9\u83cc\u7d20\u8bf1\u5bfcB16\u9ed1\u8272\u7d20\u7624\u7ec6\u80de\u51cb\u4ea1\u3002<\/a>Crotts MS\u3001Jacobs JC\u3001Baer RW\u3001Cox JL\u3002\u6297\u764c\u836f\u7269\u5316\u5b66\u30022025;25(4):244-256\u3002doi: 10.2174\/0118715206325844240909144543\u3002PMID\uff1a39411968<\/li>\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36132145\/\">\u4f0a\u7ef4\u83cc\u7d20\u7684\u836f\u7269\u518d\u5229\u7528\u53ef\u6d88\u9664\u4e2d\u6027\u7c92\u7ec6\u80de\u80de\u5916\u9677\u9631\u5e76\u963b\u6b62\u9ed1\u8272\u7d20\u7624\u8f6c\u79fb\u3002<\/a>\u5f20\u5b8f\uff0c\u5f90X\uff0c\u5f90R\uff0c\u53f6T.\u524d\u5b89\u79d1\u5c14\u3002 2022 \u5e74 9 \u6708 5 \u65e5\uff1b12:989167\u3002 doi\uff1a10.3389\/fonc.2022.989167\u3002\u7535\u5b50\u9986\u85cf 2022\u3002PMID\uff1a36132145\u514d\u8d39PMC\u6587\u7ae0\u3002<\/li>\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38794139\/\">\u5229\u7528\u8ba1\u7b97\u6a21\u578b\u8bc6\u522b\u9776\u5411\u8f6c\u79fb\u6027\u53bb\u52bf\u62b5\u6297\u6027\u524d\u5217\u817a\u764c\u7684\u836f\u7269\uff0c\u8be5\u764c\u75c7\u7684\u7279\u5f81\u662f\u7cd6\u9175\u89e3\u589e\u5f3a\u3002<\/a>\u82cfMC\uff0c\u674eAM\uff0c\u5f20W\uff0cMaeser D\uff0cGruener RF\uff0c\u9093Y\uff0c\u9ec4RS\u3002Pharmaceuticals (Basel). 2024 \u5e74 4 \u6708 29 \u65e5;17(5):569\u3002doi: 10.3390\/ph17050569\u3002PMID\uff1a38794139\u514d\u8d39PMC\u6587\u7ae0\u3002<\/li>\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41174257\/\">\u6562\u6b7b\u961f\uff1a\u88ab\u5ffd\u89c6\u7684\u6297\u764c\u836f\u7269\u3002<\/a>Deshpande AJ\u3001Munoz J\u3001Kurzrock R.Curr Oncol Rep. 2025 \u5e74 11 \u6708\uff1b27(11):1312-1330\u3002doi\uff1a10.1007\/s11912-025-01721-y\u30022025 \u5e74 11 \u6708 1 \u65e5\u5728\u7ebf\u53d1\u8868\u3002PMID\uff1a41174257\u5ba1\u67e5\u3002<\/li>\n<\/ul>\n<p class=\"wp-block-paragraph\"><a 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\u585e\u62c9\u83cc\u7d20\uff1a\u4e00\u79cd\u65b0\u578b\u5e7f\u8c31\u72ac\u732b\u7528\u5185\u5bc4\u751f\u866b\u6740\u706d\u5242\u3002\u517d\u533b\u5bc4\u751f\u866b\u5b66\u6742\u5fd7\u30022000;91(3-4):163\u2013176\u3002doi: 10.1016\/s0304-4017(00)00289-2\u3002-&nbsp;<a href=\"https:\/\/doi.org\/10.1016\/s0304-4017(00)00289-2\">DOI<\/a>&nbsp;&#8211;&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/10940519\/\">PubMed<\/a><\/li>\n<\/ol>\n<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>2020\u5e74\u4e2d\u56fd\u5b89\u5fbd\u611f\u67d3\u4e0e\u514d\u75ab\u91cd\u70b9\u5b9e\u9a8c\u5ba4\u7684\u56e2\u961f\u5728\u300aPharmacological  &hellip; <a href=\"http:\/\/zydq.1006ss.com\/?p=67439\">\u7ee7\u7eed\u9605\u8bfb <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[70],"tags":[194],"class_list":["post-67439","post","type-post","status-publish","format-standard","hentry","category-70","tag-194"],"_links":{"self":[{"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=\/wp\/v2\/posts\/67439","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=67439"}],"version-history":[{"count":0,"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=\/wp\/v2\/posts\/67439\/revisions"}],"wp:attachment":[{"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=67439"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=67439"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=67439"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}