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\u5462\uff1f<\/p>\n<p>\u4e00. \u4ec0\u4e48\u662f\u5e26\u72b6\u75b1\u75b9\u540e\u795e\u7ecf\u75db<\/p>\n<p> \u5e26\u72b6\u75b1\u75b9\u540e\u795e\u7ecf\u75db\uff08Postherpetic Neuralgia, PHN\uff09\u662f\u7531\u6c34\u75d8-\u5e26\u72b6\u75b1\u75b9\u75c5\u6bd2\uff08Varicella-Zoster Virus, VZV\uff09\u518d\u6fc0\u6d3b\u5f15\u8d77\u7684\u5e26\u72b6\u75b1\u75b9\uff08Herpes Zoster, HZ\uff09\u6700\u5e38\u89c1\u7684\u3001\u6700\u75db\u82e6\u7684\u957f\u671f\u5e76\u53d1\u75c7\u3002\u5176\u5178\u578b\u75c7\u72b6\u5305\u62ec\u5728\u76ae\u75b9\u6108\u5408\u540e\uff0c\u6cbf\u53d7\u7d2f\u795e\u7ecf\u533a\u57df\u6301\u7eed\u6216\u95f4\u65ad\u7684\u523a\u75db\u3001\u70e7\u707c\u75db\u3001\u5f02\u5e38\u6027\u75bc\u75db\u3001\u611f\u89c9\u5f02\u5e38\u3001\u7619\u75d2\u3001\u611f\u89c9\u8fdf\u949d\u548c\u75db\u89c9\u654f\u611f\u3002PHN\u7684\u75c5\u7406\u751f\u7406\u673a\u5236\u5c1a\u672a\u5b8c\u5168\u660e\u786e\uff0c\u53ef\u80fd\u4e0e\u75c5\u6bd2\u5f15\u8d77\u7684\u795e\u7ecf\u635f\u4f24\u3001\u708e\u75c7\u53cd\u5e94\u3001\u795e\u7ecf\u654f\u5316\u53ca\u795e\u7ecf\u5143\u7ed3\u6784\u7684\u53ef\u5851\u6027\u53d8\u5316\u6709\u5173\u3002<\/p>\n<p>\u4e8c. 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\u75c5\u53d8\u7b49\uff09\u65b9\u9762\u5177\u6709\u79ef\u6781\u4f5c\u7528\u3002<\/p>\n<p>\u4e09\u3001\u7ef4\u751f\u7d20D\u5728\u5e26\u72b6\u75b1\u75b9\u540e\u795e\u7ecf\u75db\uff08PHN\uff09\u4e2d\u7684\u4f5c\u7528\u673a\u5236<\/p>\n<p>1. \u514d\u75ab\u8c03\u8282\u4f5c\u7528\uff1a\u7ef4\u751f\u7d20D\u901a\u8fc7\u591a\u79cd\u9014\u5f84\u8c03\u8282\u514d\u75ab\u7cfb\u7edf\uff1a<\/p>\n<ul>\n<li data-track='22'>\u56fa\u6709\u514d\u75ab\uff1a\u7ef4\u751f\u7d20D\u901a\u8fc7\u4e0e\u7ef4\u751f\u7d20D\u53d7\u4f53\uff08VDR\uff09\u7ed3\u5408\uff0c\u523a\u6fc0\u5de8\u566c\u7ec6\u80de\u548c\u5355\u6838\u7ec6\u80de\u7684\u6297\u83cc\u6d3b\u6027\uff0c\u4fc3\u8fdb\u6297\u83cc\u80bd\uff08\u5982cathelicidin\uff09\u7684\u5408\u6210\uff0c\u4ece\u800c\u589e\u5f3a\u673a\u4f53\u5bf9\u7ec6\u83cc\u548c\u75c5\u6bd2\u7684\u62b5\u6297\u529b\u3002<\/li>\n<li data-track='23'>\u9002\u5e94\u6027\u514d\u75ab\uff1a\u7ef4\u751f\u7d20D\u5f71\u54cdB\u7ec6\u80de\u548cT\u7ec6\u80de\u7684\u5206\u5316\u4e0e\u589e\u6b96\uff0c\u51cf\u5c11\u4fc3\u708e\u7ec6\u80de\u56e0\u5b50\u7684\u5408\u6210\uff0c\u4fc3\u8fdb\u6297\u708e\u7ec6\u80de\u56e0\u5b50\u7684\u751f\u6210\uff0c\u4ece\u800c\u964d\u4f4e\u708e\u75c7\u53cd\u5e94\u3002\u7814\u7a76\u8868\u660e\uff0c\u7ef4\u751f\u7d20D\u80fd\u6291\u5236\u4e3b\u8981\u7ec4\u7ec7\u76f8\u5bb9\u6027\u590d\u5408\u4f53\uff08MHC\uff09II\u7c7b\u5206\u5b50\u7684\u8868\u8fbe\uff0c\u5e72\u9884\u6297\u539f\u5448\u9012\u7ec6\u80de\u7684\u529f\u80fd\u3002<\/li>\n<\/ul>\n<p>2. \u5bf9\u795e\u7ecf\u7ec6\u80de\u7684\u4f5c\u7528\uff1a\u7ef4\u751f\u7d20D\u5bf9\u795e\u7ecf\u7ec6\u80de\u7684\u751f\u957f\u3001\u5206\u5316\u548c\u4fee\u590d\u6709\u663e\u8457\u5f71\u54cd\uff1a<\/p>\n<ul>\n<li data-track='26'>\u795e\u7ecf\u5143\u751f\u6210\u4e0e\u5206\u5316\uff1a\u7ef4\u751f\u7d20D\u901a\u8fc7\u5f71\u54cdWnt\/\u03b2-catenin\u4fe1\u53f7\u901a\u8def\uff0c\u8c03\u8282\u795e\u7ecf\u5143\u7684\u751f\u6210\u548c\u5206\u5316\uff0c\u4fc3\u8fdb\u8f74\u7a81\u751f\u957f\u3002<\/li>\n<li data-track='27'>\u795e\u7ecf\u751f\u957f\u56e0\u5b50\u7684\u8868\u8fbe\uff1a\u7ef4\u751f\u7d20D\u80fd\u8bf1\u5bfc\u795e\u7ecf\u751f\u957f\u56e0\u5b50\uff08NGF\uff09\u7684\u8868\u8fbe\uff0c\u4fc3\u8fdb\u795e\u7ecf\u5143\u7684\u751f\u957f\u548c\u6210\u719f\uff0c\u8c03\u8282\u75db\u89c9\u611f\u53d7\u5668\u7684\u8868\u578b\u548c\u654f\u611f\u6027\u3002<\/li>\n<li data-track='28'>\u795e\u7ecf\u5e72\u7ec6\u80de\u7684\u4f5c\u7528\uff1a\u7ef4\u751f\u7d20D\u901a\u8fc7\u4e0a\u8c03\u795e\u7ecf\u5e72\u7ec6\u80de\uff08NSCs\uff09\u4e2dVDR\u7684\u8868\u8fbe\uff0c\u4fc3\u8fdb\u591a\u79cd\u795e\u7ecf\u8425\u517b\u56e0\u5b50\u7684\u5408\u6210\uff08\u5982BDNF\u3001CNTF\u3001GDNF\uff09\uff0c\u4ece\u800c\u652f\u6301\u795e\u7ecf\u518d\u751f\u548c\u4fee\u590d\u3002<\/li>\n<\/ul>\n<p>3. \u6297\u6c27\u5316\u4e0e\u6297\u708e\u4f5c\u7528\uff1a\u7ef4\u751f\u7d20D\u5728\u6297\u6c27\u5316\u548c\u6297\u708e\u65b9\u9762\u7684\u4f5c\u7528\u673a\u5236\u5305\u62ec\uff1a<\/p>\n<ul>\n<li data-track='31'>\u964d\u4f4e\u6c27\u5316\u5e94\u6fc0\uff1a\u7ef4\u751f\u7d20D\u7684\u8865\u5145\u53ef\u4ee5\u964d\u4f4e\u6c27\u5316\u5e94\u6fc0\u53c2\u6570\uff0c\u589e\u52a0\u6297\u6c27\u5316\u5242\uff08\u5982\u8c37\u80f1\u7518\u80bd\uff09\u7684\u6c34\u5e73\uff0c\u51cf\u8f7b\u795e\u7ecf\u635f\u4f24\u3002<\/li>\n<li data-track='32'>\u6291\u5236\u708e\u75c7\u53cd\u5e94\uff1a\u7ef4\u751f\u7d20D\u901a\u8fc7\u6291\u5236NF-\u03baB\u901a\u8def\uff0c\u51cf\u5c11\u4fc3\u708e\u7ec6\u80de\u56e0\u5b50\u7684\u4ea7\u751f\uff08\u5982TNF-\u03b1\u3001IL-1\u03b2\u3001IL-6\uff09\uff0c\u540c\u65f6\u4fc3\u8fdb\u6297\u708e\u7ec6\u80de\u56e0\u5b50\uff08\u5982IL-10\uff09\u7684\u751f\u6210\uff0c\u4ece\u800c\u964d\u4f4e\u795e\u7ecf\u7cfb\u7edf\u7684\u708e\u75c7\u53cd\u5e94\u3002<\/li>\n<\/ul>\n<p>4. \u6297\u75c5\u6bd2\u4f5c\u7528\uff1a\u7ef4\u751f\u7d20D\u5728\u6297\u75c5\u6bd2\u65b9\u9762\u7684\u4f5c\u7528\u673a\u5236\u5305\u62ec\uff1a<\/p>\n<p> 1\uff09 \u589e\u5f3a\u6297\u75c5\u6bd2\u514d\u75ab\uff1a\u7ef4\u751f\u7d20D\u88ab\u8ba4\u4e3a\u662f\u4e00\u79cd\u5929\u7136\u7684\u6297\u75c5\u6bd2\u4ecb\u8d28\uff0c\u80fd\u591f\u589e\u5f3a\u673a\u4f53\u5bf9\u6c34\u75d8-\u5e26\u72b6\u75b1\u75b9\u75c5\u6bd2\uff08Varicella-Zoster Virus, VZV\uff09\u7684\u514d\u75ab\u53cd\u5e94\uff0c\u964d\u4f4e\u75c5\u6bd2\u8f7d\u91cf\uff0c\u4ece\u800c\u51cf\u8f7bPHN\u7684\u75bc\u75db\u3002<\/p>\n<p> 2\uff09 \u5f71\u54cd\u6297\u75c5\u6bd2\u6cbb\u7597\u7684\u6548\u679c\uff1a\u7814\u7a76\u8868\u660e\uff0c\u7ef4\u751f\u7d20D\u6c34\u5e73\u4e0e\u6297\u75c5\u6bd2\u6cbb\u7597\u7684\u6548\u679c\u76f8\u5173\uff0c\u8db3\u591f\u7684\u7ef4\u751f\u7d20D\u6c34\u5e73\u53ef\u80fd\u63d0\u9ad8\u6297\u75c5\u6bd2\u836f\u7269\u7684\u7597\u6548\u3002<\/p>\n<p>5. \u7ef4\u751f\u7d20D\u4e0e\u9057\u4f20\u591a\u6837\u6027<\/p>\n<p> \u7ef4\u751f\u7d20D\u7684\u751f\u7269\u6d3b\u6027\u901a\u8fc7\u4e0eVDR\u7ed3\u5408\u53d1\u6325\u4f5c\u7528\uff0cVDR\u4f5c\u4e3a\u6838\u8f6c\u5f55\u56e0\u5b50\uff0c\u80fd\u591f\u8c03\u63a7\u4e0e\u75bc\u75db\u4fe1\u53f7\u901a\u8def\u76f8\u5173\u7684\u591a\u79cd\u57fa\u56e0\u7684\u8868\u8fbe\u3002\u7814\u7a76\u53d1\u73b0\uff0c\u7ef4\u751f\u7d20D\u7684\u6c34\u5e73\u4e0e\u4e2a\u4f53\u5bf9\u75bc\u75db\u548c\u963f\u7247\u7c7b\u836f\u7269\u7684\u654f\u611f\u6027\u5b58\u5728\u76f8\u5173\u6027\uff0c\u63d0\u793a\u7ef4\u751f\u7d20D\u53ef\u80fd\u5728\u9057\u4f20\u6613\u611f\u6027\u4e2d\u53d1\u6325\u4f5c\u7528\u3002<\/p>\n<p>6. \u7ef4\u751f\u7d20D\u4e0e\u80a0\u9053\u83cc\u7fa4\u7684\u76f8\u4e92\u4f5c\u7528<\/p>\n<p> \u7ef4\u751f\u7d20D\u6c34\u5e73\u4f1a\u5f71\u54cd\u80a0\u9053\u83cc\u7fa4\u7684\u7ec4\u6210\uff0c\u80a0\u9053\u83cc\u7fa4\u7684\u5931\u8c03\u4e0e\u795e\u7ecf\u6027\u708e\u75c7\u53ca\u75bc\u75db\u611f\u77e5\u76f8\u5173\u3002\u7814\u7a76\u8868\u660e\uff0c\u7ef4\u751f\u7d20D\u7f3a\u4e4f\u53ef\u80fd\u5bfc\u81f4\u80a0\u9053\u5fae\u751f\u7269\u7fa4\u7684\u53d8\u5316\uff0c\u4ece\u800c\u5f71\u54cd\u75bc\u75db\u611f\u77e5\u548c\u795e\u7ecf\u708e\u75c7\u7684\u53d1\u751f\u3002<\/p>\n<p>\u56db. \u603b\u7ed3<\/p>\n<p> \u5e26\u72b6\u75b1\u75b9\u540e\u795e\u7ecf\u75db\u662f\u4e00\u79cd\u4e25\u91cd\u5f71\u54cd\u60a3\u8005\u751f\u6d3b\u8d28\u91cf\u7684\u6162\u6027\u75bc\u75db\u72b6\u6001\u3002\u7ef4\u751f\u7d20D\u901a\u8fc7\u591a\u91cd\u673a\u5236\u5728\u5e26\u72b6\u75b1\u75b9\u540e\u795e\u7ecf\u75db\uff08Postherpetic Neuralgia, PHN\uff09\u6cbb\u7597\u4e2d\u53d1\u6325\u4f5c\u7528\uff0c\u5305\u62ec\u514d\u75ab\u8c03\u8282\u3001\u795e\u7ecf\u7ec6\u80de\u4fee\u590d\u3001\u6297\u6c27\u5316\u548c\u6297\u708e\u3001\u6297\u75c5\u6bd2\u4f5c\u7528\u7b49\u3002\u8fd9\u4e9b\u673a\u5236\u5171\u540c\u4f5c\u7528\uff0c\u6709\u52a9\u4e8e\u51cf\u8f7bPHN\u60a3\u8005\u7684\u75bc\u75db\u548c\u6539\u5584\u5176\u751f\u6d3b\u8d28\u91cf\u3002\u7ef4\u751f\u7d20D\u5728\u5e26\u72b6\u75b1\u75b9\u540e\u795e\u7ecf\u75db\uff08Postherpetic Neuralgia, PHN\uff09\u7684\u9884\u9632\u548c\u6cbb\u7597\u4e2d\u663e\u793a\u51fa\u826f\u597d\u7684\u6f5c\u529b\uff0c\u56e0\u5176\u5177\u6709\u514d\u75ab\u8c03\u8282\u3001\u795e\u7ecf\u4fee\u590d\u3001\u6297\u6c27\u5316\u548c\u6297\u708e\u7b49\u591a\u91cd\u4f5c\u7528\u3002\u968f\u7740\u5168\u7403\u8001\u9f84\u5316\u7684\u52a0\u5267\uff0c\u5e26\u72b6\u75b1\u75b9\u540e\u795e\u7ecf\u75db\uff08Postherpetic Neuralgia, PHN\uff09\u7684\u53d1\u75c5\u7387\u5c06\u4f1a\u589e\u52a0\uff0c\u56e0\u6b64\uff0c\u7ef4\u751f\u7d20D\u7684\u8865\u5145\u4f5c\u4e3a\u4e00\u79cd\u5b89\u5168\u3001\u4f4e\u6210\u672c\u7684\u6cbb\u7597\u9009\u62e9\uff0c\u503c\u5f97\u8fdb\u4e00\u6b65\u7684\u7814\u7a76\u548c\u4e34\u5e8a\u5e94\u7528\u3002\u672a\u6765\u9700\u8981\u66f4\u591a\u7684\u524d\u77bb\u6027\u3001\u591a\u4e2d\u5fc3\u3001\u5927\u89c4\u6a21\u7684\u968f\u673a\u5bf9\u7167\u7814\u7a76\u6765\u9a8c\u8bc1\u7ef4\u751f\u7d20D\u5728PHN\u6cbb\u7597\u4e2d\u7684\u6709\u6548\u6027\u548c\u5b89\u5168\u6027\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u5f53\u6211\u4eec\u5f97\u4e86\u5e26\u72b6\u75b1\u75b9\u6216\u5e26\u72b6\u75b1\u75b9\u540e\u795e\u7ecf\u75db\u7684\u65f6\u5019\uff0c\u533b\u751f\u5f80\u5f80\u4f1a\u7ed9\u6211\u4eec\u53e3\u670d\u6216\u808c\u8089\u6ce8\u5c04\u7ef4\u751f\u7d20 &hellip; <a href=\"http:\/\/zydq.1006ss.com\/?p=62194\">\u7ee7\u7eed\u9605\u8bfb <span 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