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\u8fd9\u79cd\u5f25\u6f2b\u578b\u7684\u6ee4\u6ce1\u6027\u6dcb\u5df4\u7624\uff0c\u4ed6\u8bca\u6709\u6761\u4ef6\u8981\u6c42\u7ec6\u80de\u7684\u5f62\u6001\u662f\u4f4e\u7ea7\u522b\u7684\u5f62\u6001\uff0c\u4e5f\u5c31\u662f\u4e00\u7ea7\u6216\u8005\u662f\u4e8c\u7ea7\u7684\u6ee4\u6ce1\u6027\u6dcb\u5df4\u7624\u7684\u5f62\u6001\uff0c\u5982\u679c\u662f\u4e00\u4e2a\u9ad8\u7ea7\u522b\u7684\u5f62\u6001\uff0c\u4e09\u7ea7\u7684\u5f62\u6001\u53c8\u662f\u5b8c\u5168\u5f25\u6f2b\u7684\u5206\u5e03\uff0c\u8fd9\u4e2a\u65f6\u5019\u4e0d\u8bca\u65ad\u662f\u6ee4\u6ce1\u6027\u6dcb\u5df4\u7624\uff0c\u5e94\u8be5\u8bca\u65ad\u5f25\u6f2b\u6027\u5927B\u7ec6\u80de\u6dcb\u5df4\u7624\uff0c<\/p>\n

\u8fd9\u5c31\u662f\u5728\u4e00\u4e9b\u7a7f\u523a\u7684\u5c0f\u7684\u6d3b\u68c0\u6807\u672c\u5f53\u4e2d\uff0c\u4e0d\u5efa\u8bae\u8bca\u65ad\u5f25\u6f2b\u6027\u7684\u6ee4\u6ce1\u6027\u6dcb\u5df4\u7624\uff0c\u56e0\u4e3a\u5f80\u5f80\u5f25\u6f2b\u578b\u7684\u6ee4\u6ce1\u6027\u6dcb\u5df4\u7624\u662f\u5f88\u7f55\u89c1\u7684\u3002\u5728\u7a7f\u523a\u6807\u672c\u5f53\u4e2d\u770b\u5230\u7684\u5b8c\u5168\u662f\u4e00\u4e2a\u5f25\u6f2b\u7684\u533a\u57df\uff0c\u6709\u53ef\u80fd\u4ee3\u8868\u7684\u662f\u4e00\u4e2a\u6ee4\u6ce1\u5916\uff0c\u5176\u5b9e\u662f\u6709\u6ee4\u6ce1\u7ed3\u6784\u7684\uff0c\u53d6\u6750\u6b63\u597d\u53d6\u7684\u6ee4\u6ce1\u5916\u7684\u5f25\u6f2b\u7684\u533a\u57df\uff0c\u56e0\u6b64\u5728\u7a7f\u523a\u6d3b\u68c0\u7684\u65f6\u5019\u6211\u4e0d\u5efa\u8bae\u8bca\u65ad\u5f25\u6f2b\u578b\u7684\u6ee4\u6ce1\u6027\u6dcb\u5df4\u7624\u3002<\/p>\n<\/p>\n

3B—\u6ee4\u6ce1\u6027\u5927B\u7ec6\u80de\u6dcb\u5df4\u7624\uff0c<\/p>\n<\/p>\n

\u6ee4\u6ce1\u6027\u6dcb\u5df4\u7624\uff0c\u5b83\u4e3b\u8981\u662f\u4e2d\u7b49\u5927\u5c0f\u7684\u6bcd\u7ec6\u80de\u7684\u5f62\u6001\uff0c\uff0c\u81f3\u6211\u4eec\u5f52\u4e3a\u4e09\u7ea7\uff0c\u5c31\u662f3A\u7ea7\uff0c\u9ad8\u7ea7\u522b\u7684\u6ee4\u6ce1\u6027\u6dcb\u5df4\u7624\u3002<\/p>\n

\u6216\u8005\u662f\u4ee5\u5927\u7684\u4e2d\u5fc3\u6027\u7ec6\u80de\u4e3a\u4e3b\u7684\u6ee4\u6ce1\u6027\u6dcb\u5df4\u7624\uff0cKI-67\u5176\u5b9e\u6307\u6570\u4e5f\u5f88\u9ad8\uff0c\u56e0\u4e3a\u5b83\u4e2d\u5fc3\u6bcd\u7ec6\u80de\u5f88\u5c11\uff0c\u4e3b\u8981\u662f\u5927\u7684\u4e2d\u5fc3\u7ec6\u80de\u4e3a\u4e3b\uff0c\u53ef\u80fd\u8fd8\u662f\u653e\u5728\u4f4e\u7ea7\u522b\u91cc\u9762\uff0c\u8ddf\u5b83\u7684\u751f\u7269\u5b66\u884c\u4e3a\u5e76\u4e0d\u80fd\u5339\u914d\u8d77\u6765\uff0c\u7b2c\u4e94\u7248\u662f\u628a\u5b83\u653e\u5728\u96be\u4ee5\u5f52\u7c7b\u91cc\u9762<\/p>\n<\/p>\n

\u5f25\u6f2b\u7684\u533a\u57df\uff0c\u7b26\u5408\u4e86\u9ad8\u7ea7\u522b\u6ee4\u6ce1\u6027\u6dcb\u5df4\u7624\u7684\u8bca\u65ad\u6807\u51c6—\u5f25\u6f2b\u7684\u533a\u57df\u6ca1\u6709\u6ee4\u6ce1\u6570\u7a81\u7f51\uff0c\u7ec6\u80de\u5f62\u6001\u53c8\u7b26\u54083a\u7ea7\u6216\u8005\u662f3B\u7ea7\u5f62\u6001\uff0c\u6211\u4eec\u5c31\u53ef\u4ee5\u8bca\u65ad\u5b83\u662f\u4f34\u6709\u5f25\u6f2b\u6027\u5927B\u7ec6\u80de\u6dcb\u5df4\u7624\u6216\u8005\u662f\u9ad8\u7ea7\u522bB\u7ec6\u80de\u6dcb\u5df4\u7624\u7684\u8f6c\u6362<\/p>\n

\u5230\u5e95\u662f\u8f6c\u5316\u4e3a\u5f25\u6f2b\u6027\u5927b\u7ec6\u80de\u6dcb\u5df4\u7624\u8fd8\u662f\u4e00\u4e2a\u9ad8\u7ea7\u522b\u7684B\u7ec6\u80de\u6dcb\u5df4\u7624\uff0c\u8fd9\u4e2a\u65f6\u5019\u6211\u4eec\u8981\u505aFISH\u7684\u68c0\u6d4b<\/p>\n<\/p>\n<\/p>\n

\u7f55\u89c1\u7684\u5f62\u6001\u5b66\u7684\u53d8\u5f02<\/p>\n<\/p>\n

BCL-2\u9633\u7684\u662f\u751f\u53d1\u4e2d\u5fc3\u7684B\u7ec6\u80de<\/p>\n

a\u56fe—-\u6ee4\u6ce1\u6837\u7684\u7ed3\u6784\uff0c\u751f\u53d1\u4e2d\u5fc3\u73bb\u7483\u6837\u53d8\u6027\uff0c\u7ea2\u67d3–\u73bb\u7483\u6837\u53d8\u7684\u80f6\u539f<\/p>\n

\u6ee4\u6ce1\u5468\u56f4\u6709\u70b9\u50cf\u6d0b\u8471\u76ae\u56f4\u7ed5\uff0c\u5f88\u50cf\u900f\u660e\u8840\u7ba1\u578bcastleman \u75c5\uff0c<\/p>\n<\/p>\n

B\u56fe\u663e\u793a\u7684\u662f\u6dcb\u5df4\u6ee4\u6ce1\u8840\u7ba1\u63d2\u5165<\/p>\n<\/p>\n

C\u56fe\u5b83\u663e\u793a\u7684\u662f\u5728\u6dcb\u5df4\u6ee4\u6ce1\u4e4b\u95f4\uff0c\u53ef\u4ee5\u770b\u5230\u8fd9\u4e9b\u589e\u751f\u7684\u8840\u7ba1\uff0c\u8fd9\u4e5f\u5f88\u7c7b\u4f3ccastleman \u75c5\u900f\u660e\u8840\u7ba1\u578b\u5f62\u6001\u6539\u53d8<\/p>\n<\/p>\n

\u53d8\u578b2–\u6d46\u6837\u5206\u5316\uff0c\u6ee4\u6ce1\u6811\u7a81\u7f51\u4f34\u968f<\/p>\n

\u03ba\u03bb\u9650\u5236\u6027\u8868\u8fbe<\/p>\n

IgG4\u9633\u6027\u7684\u6d46\u7ec6\u80de\u5347\u9ad8\uff0c\u80c6\u7ba1\u7ec6\u80de\u764c\uff0c\u6dcb\u5df4\u9020\u8840\u80bf\u7624–\u6ee4\u6ce1\uff0c\u8fb9\u7f18\u533a\uff0c\u6ee4\u6ce1\u6811\u7a81\u7ec6\u80de\u8089\u7624\u53ef\u4ee5\u5408\u5e76IgG4\u9633\u6027\u7684\u6d46\u7ec6\u80de\u5347\u9ad8\u3002<\/p>\n<\/p>\n

HE \u770b\u4e0d\u51fa\u5f02\u5e38—\u514d\u75ab\u7ec4\u531610\uff0cBCL-2\u6709\u5f02\u5e38\uff0c\u6ee4\u6ce1\u7f51\u4f34\u968f—\u6ee4\u6ce1\u6dcb\u5df4\u7624<\/p>\n<\/p>\n

\u5176\u5b9e\u662f\u4e00\u4e2a\u539f\u4f4d\u6ee4\u6ce1\u6027\u7684\u80bf\u7624\uff0c\u4ece\u5f62\u6001\u4e0a\u9762\u6839\u672c\u5c31\u4e0d\u80fd\u8bc6\u522b\uff0c\u5982\u679c\u4e0d\u505a\u514d\u75ab\u7684\u8bdd\uff0c\u6211\u4eec\u6839\u672c\u5c31\u4ece\u5f62\u6001\u4e0a\u9762\u5f88\u96be\u8bc6\u522b\u662f\u4e00\u4e2a\u6ee4\u6ce1\u6027\u7684\u80bf\u7624\uff0c\u5f88\u591a\u7684\u60c5\u51b5\u4e0b\u662f\u8ddf\u5176\u4ed6\u7684B\u7ec6\u80de\u7684\u6dcb\u5df4\u7624\uff0c\u5305\u62ec\u7ecf\u5178\u6027\u7684\u6ee4\u6ce1\u6027\u6dcb\u5df4\u7624\uff0c\u5957\uff0c\u8fb9\u7f18\uff0c\u5927B\u5171\u5b58<\/p>\n<\/p>\n

\u7f16\u78011<\/p>\n<\/p>\n

\u5341\u4e8c\u6307\u80a0\u7684\u75c5\u53d8\uff0c\u75c5\u53d8\u91cc\u9762\u7c98\u819c\u591a\u4e2a\u6dcb\u5df4\u6ee4\u6ce1\u6837\u7ed3\u6784\uff0c\u4ece\u5f62\u6001\u4e0a\u9762\u53ef\u4ee5\u770b\u5230\u8fd9\u4e9b\u6dcb\u5df4\u6ee4\u6ce1\u7684\u7ed3\u6784\uff0c\u5f62\u6001\u548c\u67d3\u8272\u90fd\u662f\u6bd4\u8f83\u4e00\u81f4\u7684\uff0c<\/p>\n<\/p>\n

\u8fd9\u4e24\u4e2a\u6dcb\u5df4\u6ee4\u6ce1\u7684\u67d3\u8272\u57fa\u672c\u4e0a\u662f\u4e00\u81f4\u7684\uff0c\u4e5f\u5c31\u662f\u8bf4\u5b83\u6ca1\u6709\u6b63\u5e38\u7684\u521d\u671f\u6dcb\u5df4\u6ee4\u6ce1\u7684\u793e\u4f1a\u6027\u7684\u5b58\u5728\uff0c\u67d3\u8272\u7684\u4e00\u81f4\u6027–\u7ec6\u80de\u6210\u5206\u662f\u6bd4\u8f83\u4e00\u81f4\u7684\uff0c\u662f\u4e00\u4e2a\u5355\u514b\u9686\u6027\u7684\u75c5\u53d8\uff0c\u9996\u5148\u8981\u8003\u8651\u662f\u80bf\u7624\u6027<\/p>\n<\/p>\n

\u4e2d\u5fc3\u6837\u7684\u7ec6\u80de—–\u6838\u62c9\u957f\u6709\u4e00\u4e9b\u626d\u66f2\uff0c<\/p>\n<\/p>\n

\u91cc\u9762\u6709\u4e00\u4e9b\u6563\u6563\u7684\u6709\u6838\u4ec1\u7684\u7ec6\u80de\uff0c\u660e\u663e\u7684\u6bd4\u8f83\u5927\uff0c\u6838\u6709\u70b9\u7a7a\uff0c\u6838\u819c\u6bd4\u8f83\u6e05\u695a\uff0c\u6709\u4e00\u4e2a\u5c0f\u6838\u4ec1—\u6ee4\u6ce1\u6811\u7a81\u7ec6\u80de<\/p>\n<\/p>\n

\u514d\u75ab\u652f\u6301\u5b83\u662f\u4e00\u4e2a\u6ee4\u6ce1\u6027\u6dcb\u5df4\u7624\uff0c\u6ee4\u6ce1\u6027\u6dcb\u5df4\u7624\u53d1\u751f\u5728\u80c3\u80a0\u9053\uff0c\u662f\u4e00\u4e2a\u4f4e\u7ea7\u522b\u7684\u5f62\u6001\uff0c\u8981\u53bb\u9274\u522b\u5b83\u5230\u5e95\u662f\u4e00\u4e2a\u7ecf\u5178\u578b\u7684\u6ee4\u6ce1\u6027\u6dcb\u5df4\u7624\uff0c\u7d2f\u53ca\u4e86\u80c3\u80a0\u9053\uff0c\u8fd8\u662f\u4e00\u4e2a\u5341\u4e8c\u6307\u80a0\u578b\u7684\u6ee4\u6ce1\u6027\u6dcb\u5df4\u7624\uff0c\u8fd9\u4e2a\u75c5\u4f8b\u6700\u7ec8\u8bc1\u5b9e\u5c31\u662f\u4e00\u4e2a\u5341\u4e8c\u6307\u80a0\u578b\u7684\u6ee4\u6ce1\u6027\u6dcb\u5df4\u7624—-\u66f4\u60f0\u6027\u7684\u751f\u7269\u5b66\u884c\u4e3a\uff0c\u90a3\u4e48\u4e34\u5e8a\u5f80\u5f80\u4e0d\u9700\u8981\u6cbb\u7597\uff0c\u75c5\u4eba\u7684\u89c2\u5bdf\u968f\u8bbf\u5c31\u53ef\u4ee5\u4e86<\/p>\n<\/p>\n<\/p>\n<\/p>\n<\/p>\n<\/p>\n

u<\/p>\n<\/p>\n<\/p>\n<\/p>\n

\u91cf\u591a<\/p>\n

\u8d28–\u67d3\u8272\u4e00\u81f4–\u514b\u9686<\/p>\n

\u751f\u957f\u65b9\u5f0f–\u4fb5\u72af\u88ab\u819c\uff0c\u8102\u80aa<\/p>\n<\/p>\n

\u6ee4\u6ce1\u7684\u67d3\u8272\u57fa\u672c\u4e0a\u662f\u4e00\u81f4\u7684\uff0c\u8fd9\u4e24\u4e2a\u7ed3\u8282\u57fa\u672c\u4e0a\u662f\u878d\u5408\u4e86\uff0c\u8bf4\u660e\u5b83\u4fb5\u72af\u4e86\u6dcb\u5df4\u6ee4\u6ce1\u7684\u5957\u533a\u8fb9\u7f18\u533a\uff0c\u526f\u76ae\u8d28\u533a<\/p>\n<\/p>\n

\u9ad8\u5185\u76ae\u9759\u8109—\u526f\u76ae\u8d28\u533a–\u6709\u6de1\u67d3\u7ec6\u80de<\/p>\n<\/p>\n<\/p>\n

\u6df1\u67d3\u7684\u5c0f\u7684\u89c4\u5219\u7684\u5c0f\u6dcb\u5df4\u7ec6\u80de\u662f\u751f\u53d1\u4e2d\u5fc3\u91cc\u9762\u7684\u6ee4\u6ce1\u8f85\u52a9T\u7ec6\u80de<\/p>\n<\/p>\n

\u6709\u6838\u4ec1\u7684\u6838\u6bd4\u8f83\u6df1\u67d3\u7684\uff0c\u6838\u819c\u4e5f\u6bd4\u8f83\u6e05\u6670\u7684\uff0c\u8fd9\u4e9b\u662f\u4e2d\u5fc3\u6bcd\u7ec6\u80de\u6837\u7684\u7ec6\u80de\uff0c<\/p>\n<\/p>\n

\u8fd8\u6709\u4e00\u4e9b\u6838\u4ec1\u4e0d\u660e\u663e\uff0c\u6838\u6709\u70b9\u62c9\u957f\u626d\u66f2\u7684\u8fd9\u4e9b\u5c31\u662f\u4e2d\u5fc3\u6837\u7684\u7ec6\u80de\u3002<\/p>\n<\/p>\n

\u6838\u7684\u67d3\u8272\u8981\u6de1\uff0c\u6ca1\u6709\u90a3\u4e48\u6df1\uff0c\u6838\u819c\u662f\u6bd4\u8f83\u6e05\u6670\uff0c\u5b83\u7684\u6838\u6210\u7a7a\u7f51\u72b6\u53ef\u4ee5\u770b\u5230\u4e00–\u4e24\u4e2a\u6838\u4ec1\uff0c—FDC\u7ec6\u80de\u5f80\u5f80\u662f\u9576\u5d4c\u5728\u8fd9\u4e9b\u6dcb\u5df4\u7ec6\u80de\u5f53\u4e2d\u5206\u5e03\u7684<\/p>\n<\/p>\n

\u4e2d\u5fc3\u6bcd—\u4e2d\u95f4\u6bcd\u7ec6\u80de\uff0c\u53ef\u4ee5\u770b\u5230\u5c11\u91cf\u7684\u80de\u6d46\uff0c\u662f\u78b1\u6027\uff0c\u55dc\u53cc\u8272<\/p>\n<\/p>\n

FDC—\u6ee4\u6ce1\u6811\u7a81\u7ec6\u80de\u5b83\u7684\u6838\u662f\u6de1\u67d3\u7684\uff0c\u6de1\u67d3\uff0c\u6838\u6210\u7a7a\u7f51\u72b6\uff0c\u6838\u819c\u6bd4\u8f83\u6e05\u6670\uff0c\u6838\u4ec1\u4e5f\u6bd4\u8f83\u6e05\u6670\uff0c\u5982\u679c\u662f\u4e24\u4e2a\u6ee4\u6ce1\u6811\u7a81\u7ec6\u80de\u805a\u96c6\u5728\u4e00\u8d77\uff0c\u5b83\u6838\u819c\u5f80\u5f80\u662f\u62c9\u76f4\u7684\u6210\u4e00\u4e2a\u76f4\u89d2<\/p>\n

\u7efc\u4e0a—\u5f62\u6001\u4e0a\u9762\u6211\u4eec\u8981\u8003\u8651\u5b83\u662f\u4e00\u4e2a\u80bf\u7624\u6027\u7684\u75c5\u53d8\uff0c\u4ece\u7ec6\u80de\u5f62\u6001\u5b83\u6709\u4e24\u7c7b\u7ec6\u80de\uff0c\u53c8\u6709\u6ee4\u6ce1\u6811\u7a81\u7ec6\u80de\uff0c\u8003\u8651\u6ee4\u6ce1\u6027\u7684\u6dcb\u5df4\u7624\uff0c<\/p>\n

\u514d\u75ab\u7ec4\u5316<\/p>\n<\/p>\n<\/p>\n

\u91cf—\u5f88\u591a\u7684\uff0c<\/p>\n

\u8d28\u7684\u67d3\u8272—-\u67d3\u8272\u90fd\u662f\u5f88\u5747\u5300\u4e00\u81f4\u7684\uff0c\u5f3a\u9633\u6027\uff0c\u63d0\u793a\u5b83\u662f\u4e00\u4e2a\u5355\u514b\u9686\u6027\u7684\u75c5\u53d8\uff0c<\/p>\n

\u5206\u5e03–\u540c\u65f6\u6ee4\u6ce1\u5916\u9762—\u6709\u8840\u7ba1\u7684\u533a\u57df\u662f\u6ee4\u6ce1\u95f4\u7684\u533a\u57df\uff0c\u4e5f\u51fa\u73b0\u4e86\u5927\u91cf\u7684CD20\u9633\u6027\u7684\u60c5\u51b5\uff0c\u50cf\u8fd9\u79cd\u5206\u5e03\u662f\u4e0d\u5bf9\u7684\u3002<\/p>\n<\/p>\n<\/p>\n

\u6ee4\u6ce1\u6811\u7a81\u7f51<\/p>\n<\/p>\n

\u8fd8\u8981\u8bc1\u660e\u662f\u751f\u53d1\u4e2d\u5fc3\u91cc\u9762\u7684B\u7ec6\u80de\uff0c\u624d\u80fd\u652f\u6301\u6ee4\u6ce1\u6027\u6dcb\u5df4\u7624<\/p>\n<\/p>\n

\u6765\u81ea\u751f\u53d1\u4e2d\u5fc3<\/p>\n<\/p>\n

\u4f4e\u4e86\u6bd4\u6b63\u5e38\uff0c\u754c\u9650\u4e0d\u6e05\u5411\u5916\u5f25\u6563\uff0c\u65e0\u6781\u6027<\/p>\n<\/p>\n<\/p>\n

\u65e0\u5176\u4ed6\u75c5\u53d8<\/p>\n<\/p>\n

\u91cf–\u591a<\/p>\n

\u8d28—\uff1f<\/p>\n

\u751f\u957f\u65b9\u5f0f<\/p>\n<\/p>\n

\u754c\u9650\u4e0d\u6e05<\/p>\n<\/p>\n

\u6ee4\u6ce1\u6837\u7684\u7ed3\u6784\u6709\u6de1\u7136\u548c\u6df1\u67d3\u7684\u533a\u57df—\u8fdb\u884c\u6027\u751f\u53d1\u4e2d\u5fc3\u8f6c\u5316\uff1f<\/p>\n<\/p>\n

\u7ec6\u80de—\u5927\u7684\u6ee4\u6ce1\u6837\u7684\u7ed3\u6784\uff0c\u6ee4\u6ce1\u91cc\u9762\u662f\u6709\u6df1\u67d3\u7684\u5c0f\u6dcb\u5df4\u7ec6\u80de\uff0c\u5927\u7684\u6709\u900f\u4eae\u80de\u6d46\u7684\u7ec6\u80de\uff0c\u5b83\u4e24\u8005\u662f\u754c\u9650\u4e0d\u6e05<\/p>\n<\/p>\n

\u8840\u7ba1\u5468\u56f4\u7684\u533a\u57df–\u9ad8\u5185\u76ae\u9759\u8109—\u526f\u76ae\u8d28\u533a\u6ca1\u6709\u90a3\u4e48\u6df1\u7684\uff0c\u63d0\u793a\u6211\u4eec\u8fd9\u91cc\u9762\u7684\u7ec6\u80de\u6210\u5206\u53ef\u80fd\u51fa\u4e86\u95ee\u9898<\/p>\n<\/p>\n

\u6df1\u67d3\uff0c\u6de1\u67d3\u4e24\u8005\u662f\u754c\u9650\u4e0d\u6e05<\/p>\n<\/p>\n

\u5c0f\u7684\u5706\u7684\u5c0f\u6dcb\u5df4\u7ec6\u80de\u4e5f\u6709\u4e2d\u5fc3\u6bcd\u7ec6\u80de\uff0c\u8fd8\u6709\u4e2d\u5fc3\u6837\u7684\u7ec6\u80de<\/p>\n<\/p>\n

\u526f\u76ae\u8d28\u533a–\u6de1—-\u88ab\u90e8\u5206\u53d6\u4ee3<\/p>\n<\/p>\n<\/p>\n

\u4e2d\u5fc3\u6bcd\u7ec6\u80de\u6837\u7684\u7ec6\u80de<\/p>\n<\/p>\n

\u9ad8\u5185\u76ae\u9759\u8109—<\/p>\n<\/p>\n

\u62c9\u957f–\u4e2d\u5fc3\u6837\u7ec6\u80de<\/p>\n<\/p>\n

\u4e2d\u5fc3\u6bcd<\/p>\n<\/p>\n

\u6ee4\u6ce1\u578bT\u7ec6\u80de\u6dcb\u5df4\u7624\u5b83\u53ef\u4ee5\u6709\u4e24\u79cd\u7ec4\u7ec7\u5b66\u6a21\u5f0f\uff0c\u4e00\u4e2a\u5c31\u662f\u5b8c\u5168\u7c7b\u4f3c\u4e8e\u6ee4\u6ce1\u6027\u6dcb\u5df4\u7624\u8fd9\u6837\u7684\u6a21\u5f0f\uff0c\u53e6\u5916\u4e00\u4e2a\u5c31\u662f\u7c7b\u4f3c\u4e8e\u751f\u53d1\u4e2d\u5fc3\u8fdb\u884c\u6027\u8f6c\u5316\u751f\u957f\u65b9\u5f0f\uff0c\u6ee4\u6ce1\u6027T\u7ec6\u80de\u6dcb\u5df4\u7624\u7684\u7ec6\u80de\u5f62\u6001\uff0c\u5b83\u4e5f\u53ef\u4ee5\u6709\u8fd9\u6837\u7684\u900f\u4eae\u7684\u80de\u6d46\uff0c\u67d3\u8272\u8d28\u5f80\u5f80\u662f\u6bd4\u8f83\u7ec6\u7684\uff0c\u5206\u5e03\u6bd4\u8f83\u5747\u5300\uff0c\u6838\u4ec1\u4e0d\u662f\u5f88\u6e05\u695a\uff0c\u6838\u819c\u4e5f\u4e0d\u6e05\u695a\uff0c<\/p>\n

\u8fd9\u4e2a\u75c5\u4f8b\u770b\u6709\u6838\u4ec1\u7684\u8fd9\u4e9b\u4e2d\u5fc3\u6bcd\u7ec6\u80de\u6837\u7684\u7ec6\u80de\uff0c\u5b83\u67d3\u8272\u8d28\u662f\u7ed3\u5757\u7684\u6bd4\u8f83\u7c97\u7684\uff0c\u6838\u819c\u4e5f\u6bd4\u8f83\u6e05\u6670<\/p>\n<\/p>\n<\/p>\n

\u6ee4\u6ce1\u6811\u7a81\u7f51\u5b58\u5728<\/p>\n<\/p>\n

\u6ee4\u6ce1\u5916\u8fb9\u4e5f\u6709<\/p>\n<\/p>\n

\u6ee4\u6ce1\u91cc\u6709\u5f3a\u6709\u5f31<\/p>\n<\/p>\n

\u6b63\u5e38<\/p>\n<\/p>\n

\u6de1\u67d3\u7ec6\u80de\u9633<\/p>\n<\/p>\n

\u6de1\u67d3\u7ec6\u80de\u9633<\/p>\n

\u8f85\u52a9T–\u9633–\u5c0f\u9ed1\u70b9<\/p>\n<\/p>\n

\u6de1\u67d3–\u9634<\/p>\n<\/p>\n

\u5957\u533aBCL-2\u53ef\u9633–\u5c0f\u6df1\u67d3\u6dcb\u5df4\u7ec6\u80de–10  6\u9634 BCL-2\u9633\uff08\u53ea\u6709\u8bc1\u660e\u4e86\u662f\u751f\u53d1\u4e2d\u5fc3\u91cc\u7684B\u7ec6\u80de\u9633\u4e86\u624d\u662f\u80bf\u7624\uff09IgD\u9633<\/p>\n<\/p>\n<\/p>\n

\u6bd4\u6b63\u5e38\u4f4e\uff0c\u5206\u5e03\u754c\u9650\u4e0d\u6e05\uff0c\u65e0\u6781\u6027—\u80bf\u7624<\/p>\n<\/p>\n

\u51fa\u53bb\u4e86—\u7edd\u5927\u591a\u6570\u662f\u80bf\u7624<\/p>\n<\/p>\n<\/p>\n<\/p>\n

\u6ee4\u6ce1<\/p>\n<\/p>\n

\u661f\u7a7a<\/p>\n

\u751f\u53d1\u4e2d\u5fc3\u548c\u5957\u754c\u9650\u6e05\u695a<\/p>\n<\/p>\n

\u661f\u7a7a\uff0c\u754c\u6e05<\/p>\n<\/p>\n

\u6bcd\u7ec6\u80de\u671f<\/p>\n<\/p>\n

\u4e2d\u5fc3\u6bcd<\/p>\n<\/p>\n

\u4e2d\u5fc3\u6bcd\u4e3a\u4e3b<\/p>\n<\/p>\n

\u541e\u566c\u7684\u7ec4\u7ec7\u7ec6\u80de<\/p>\n<\/p>\n<\/p>\n

FDC–\u6dcb\u5df4\u6ee4\u6ce1<\/p>\n<\/p>\n

\u754c\u9650\u4e0d\u6e05<\/p>\n<\/p>\n

\u6de1\u67d3\uff0c\u6df1\u67d3\u6df7\u5408<\/p>\n<\/p>\n<\/p>\n

FDC—\u6dcb\u5df4\u6ee4\u6ce1<\/p>\n<\/p>\n

\u4e2d\u5fc3\u6bcd<\/p>\n<\/p>\n

\u4e2d\u5fc3\u6837<\/p>\n

\u7efc\u4e0a–\u662f\u6dcb\u5df4\u6ee4\u6ce1\uff0c\u4fb5\u72af\u8bc1\u636e\u4e0d\u660e\u786e<\/p>\n<\/p>\n

\u5916\u8fb9\u5c11<\/p>\n<\/p>\n

\u751f\u53d1\u4e2d\u5fc3–\u5f31\u9633<\/p>\n

\u5957\u533a–\u5f3a\u9633<\/p>\n<\/p>\n<\/p>\n<\/p>\n

\u751f\u53d1\u4e2d\u5fc3–\u7a00\u758f\u6de1<\/p>\n

\u5957\u533a–\u81f4\u5bc6\uff0c\u5f3a<\/p>\n<\/p>\n<\/p>\n<\/p>\n

\u5957\u533a\u9633–6  10\u4e0d\u9633\uff0c\u4e0d\u662f\u751f\u53d1\u4e2d\u5fc3\u91cc\u7684B<\/p>\n<\/p>\n

\u5957\u533a—\u4f4e<\/p>\n<\/p>\n

\u5957\u533a\u9633<\/p>\n<\/p>\n

\u8fdb\u884c\u6027\u8f6c\u5316\u751f\u53d1\u4e2d\u5fc3\u91cc\u6709\u5957\u533a\u6dcb\u5df4\u7ec6\u80de<\/p>\n<\/p>\n

\u5957\u533a\u9633<\/p>\n<\/p>\n<\/p>\n

BCL-2\u9633–\u5fc5\u987b\u8bc1\u660e\u662f\u751f\u53d1\u4e2d\u5fc3B\uff0c\u53ea\u770b\u5230\u6ee4\u6ce1\u7ed3\u6784\u5c31\u8bca\u65adBCL-2\u9633\u6027\u7ec6\u80de\u662f\u6dcb\u5df4\u7624\u4f1a\u8bef\u8bca–\u5957\u4e5f\u53ef\u4ee5\u9633\uff08\u751f\u53d1\u4e2d\u5fc3\u8fdb\u884c\u6027\u8f6c\u5316\uff09<\/p>\n<\/p>\n

\u6ee4\u6ce1\u589e\u751f\uff0c\u5927\u5c0f\u4e0d\u4e00<\/p>\n<\/p>\n

\u513f\u7ae5\u578b–\u5934\u9888\uff0c\uff0c25\u4ee5\u4e0b\uff0c\uff0c\u4e0d\u80fd\u5f25\u6f2b-\u53ea\u80fd\u662f\u6ee4\u6ce1<\/p>\n

\u513f\u7ae5\u578b\u6ee4\u6ce1\u6027\u6dcb\u5df4\u7624\uff0c\u5f62\u6001\u4e0a\u8981\u8003\u8651———\u513f\u7ae5\u578b\u6ee4\u6ce1\u6dcb\u5df4\u7624\uff0c\u589e\u751f\u6269\u5f20\u6ee4\u6ce1\u5f62\u6001\u662f\u6709\u7279\u70b9\u7684\uff0c\u5468\u56f4\u5957\u533a\u4f1a\u6d88\u5931\uff0c\u8fd9\u4f8b–\u6ca1\u6709\u5b8c\u5168\u7684\u6d88\u5931\uff0c\uff0c\u6dcb\u5df4\u6ee4\u6ce1\u5bf9\u5957\u533a\u63a8\u6324\u5f0f\u751f\u957f<\/p>\n<\/p>\n

\u661f\u7a7a\uff0c\u6bcd\u7ec6\u80de–3A\/B<\/p>\n<\/p>\n

B<\/p>\n<\/p>\n

\u6ee4\u6ce1\uff0c\u4e0d\u80fd\u5f25\u6f2b<\/p>\n<\/p>\n

\u9634<\/p>\n<\/p>\n

\u751f\u53d1\u4e2d\u5fc3B<\/p>\n<\/p>\n

\u751f\u53d1\u4e2d\u5fc3B<\/p>\n<\/p>\n

\u5957<\/p>\n<\/p>\n

\u751f\u53d1\u4e2d\u5fc3\u8fdb\u884c\u6027\u8f6c\u5316\u6837<\/p>\n<\/p>\n

\u6392\u9664IRF-4\u91cd\u6392<\/p>\n<\/p>\n

\u5927\u4e8e30%<\/p>\n<\/p>\n<\/p>\n<\/p>\n<\/p>\n

\u5f25\u6f2b\u589e\u751f—-\u5148\u770b\u662f\u526f\u76ae\u8d28\u533a\u5417<\/p>\n<\/p>\n

\u4e0d\u662f\u526f\u76ae\u8d28\u533a\u6df1\u67d3\u6a21\u5f0f–\u6de1\u67d3\uff0c\u65e0\u9ad8\u5185\u76ae\u9759\u8109<\/p>\n

\u6240\u4ee5\u53ef\u80fd\u662f\u80bf\u7624\u6027\u7684<\/p>\n<\/p>\n

\u662f\u5c0f\u7ec6\u80de\u5f62\u6001\uff0c\u4f46\u662f\u51fa\u73b0\u6de1\u67d3\u55dc\u78b1\u6027\u80de\u6d46<\/p>\n<\/p>\n

\u7ec6\u80de\u6838\u4e0d\u89c4\u5219<\/p>\n<\/p>\n

\u6d46\u6837\u5206\u5316<\/p>\n<\/p>\n

\u5c0f\u6dcb\u5df4\u7ec6\u80de\u7684\u5f62\u6001\u6838\u578b\u4e0d\u89c4\u5219\uff0c\u80fd\u770b\u5230\u6d46\u6837\u5206\u5316\u7684\u7ec6\u80de\uff0c\u4ed6\u6709\u6bd4\u8f83\u591a\u55dc\u78b1\u6027\u7684\u80de\u6d46\uff0c\u6709\u4e00\u4e2a\u7c89\u67d3\u533a\u662f\u9ad8\u5c14\u57fa\u590d\u5408\u4f53\uff0c\u53f3\u4e24\u4e2a\u7ec6\u80de\u6211\u4eec\u53ef\u4ee5\u770b\u5230\u5047\u5305\u542b\u4f53–\u6838\u578b\u4e5f\u662f\u4e0d\u89c4\u5219\u3002<\/p>\n<\/p>\n

\u514d\u75ab\u7403\u86cb\u767d<\/p>\n<\/p>\n

\u80de\u6d46\u51fa\u6765\u4e86<\/p>\n

\u5c0fB\u7ec6\u80de\uff0c\u6709\u6d46\u6837\u5206\u5316\uff0c\u5c0fB\u7ec6\u80de\u80bf\u7624\u4f34\u6709\u6d46\u6837\u5206\u5316\u7684\u65f6\u5019\uff0c\u5982\u679c\u770b\u5230\u80a5\u5927\u7ec6\u80de\u7684\u65f6\u5019\uff0c\u9996\u5148\u8981\u8003\u8651\u5b83\u662f\u4e0d\u662f\u4e00\u4e2a\u6dcb\u5df4\u6d46\u7ec6\u80de\u6027\u6dcb\u5df4\u7624<\/p>\n<\/p>\n

\u5f25\u6f2b<\/p>\n<\/p>\n<\/p>\n<\/p>\n

6\u9634\u6027–\u4e0d\u652f\u6301\u6ee4\u6ce1\u6dcb\u5df4\u7624<\/p>\n<\/p>\n<\/p>\n

\u9650\u5236\u6027\u8868\u8fbe<\/p>\n<\/p>\n

15%<\/p>\n<\/p>\n<\/p>\n

IgM–\u5de8\u7403\u86cb\u767d\u8840\u75c7<\/p>\n<\/p>\n<\/p>\n<\/p>\n

\u6de1\u67d3\uff0c\u770b\u4e0d\u51fa\u6ee4\u6ce1\u8fd8\u662f\u5f25\u6f2b<\/p>\n<\/p>\n

\u6ee4\u6ce1\u5f71\u5b50<\/p>\n<\/p>\n

\u9ad8\u5185\u76ae\u9759\u8109–\u526f\u76ae\u8d28\u533a\uff0c\u6ee4\u6ce1\u6837\u7ed3\u6784<\/p>\n<\/p>\n

\u6838\u578b\u4e0d\u89c4\u5219\uff0c\u4e2d\u5fc3\uff0c\u4e2d\u5fc3\u6bcd<\/p>\n<\/p>\n

\u7ed3\u8282<\/p>\n<\/p>\n<\/p>\n

\u751f\u53d1\u4e2d\u5fc3B<\/p>\n<\/p>\n<\/p>\n

\u9633\u7684\u662f\u751f\u53d1\u4e2d\u5fc3\u7684B<\/p>\n<\/p>\n<\/p>\n

6,10,mum-1\u4e09\u4e2a\u90fd\u9633—\u9274\u522bIRF-4\u91cd\u6392<\/p>\n<\/p>\n<\/p>\n<\/p>\n<\/p>\n

\u878d\u5408<\/p>\n<\/p>\n

\u6ee4\u6ce1\u533a—-\u4e2d\u5fc3\u6bcd<\/p>\n<\/p>\n

\u5f25\u6f2b\u533a—\u4e2d\u7b49\u5927\u5c0f<\/p>\n<\/p>\n

\u94fa\u8def\u77f3\u6837\u6392\u5217—\u4f2f\u57fa\u7279\uff1f<\/p>\n<\/p>\n

\u9634<\/p>\n<\/p>\n

\u6ee4\u6ce1—\u6709\u7f51<\/p>\n

\u5f25\u6f2b–\u7f51\u7834\u788e<\/p>\n<\/p>\n<\/p>\n<\/p>\n

14\u5c81—\u9ad8\u7ea7\u522b\u6ee4\u6ce1\uff0c\u5f25\u6f2b\u5927B\u90fd\u7f55\u89c1<\/p>\n<\/p>\n<\/p>\n<\/p>\n

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