\u4f60\u7684\u7236\u6bcd\u662f\u5426\u63d0\u8d77\u8fc7\uff0c\u4ed6\u4eec\u66fe\u6bcf\u591c\u75db\u5f97\u7761\u4e0d\u7740\u89c9\uff1f<\/p>\n
\u4f60\u7684\u7237\u7237\u5976\u5976\u662f\u5426\u544a\u8bc9\u8fc7\u4f60\uff0c\u4ed6\u4eec\u66fe\u88ab\u201c\u86c7\u7f20\u8170\u201d\u957f\u671f\u56f0\u6270\uff1f<\/p>\n
\u201c\u8f9b\u52e4\u6253\u5de5\u4eba\u201d\u7684\u4f60\uff0c\u4f1a\u4e0d\u4f1a\u5df2\u7ecf\u5f97\u8fc7\u201c\u5e26\u72b6\u75b1\u75b9\u201d\uff1f <\/p>\n
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\u4eca\u5929\u6211\u4eec\u5c31\u6765\u4e86\u89e3\u4e00\u4e0b\u8fd9\u79cd\u4ee4\u4e0d\u5c11\u4eba\u671b\u800c\u751f\u754f\u7684\u75be\u75c5\uff01<\/p>\n
\u636e\u62a5\u9053\uff0c\u5168\u7403\u666e\u901a\u4eba\u7fa4\u5e26\u72b6\u75b1\u75b9\u7684\u53d1\u75c5\u7387\u4e3a\uff083\uff5e5\uff09\/1000\u4eba\u5e74\uff0c\u4e9a\u592a\u5730\u533a\u4e3a\uff083\uff5e10\uff09\/1000\u4eba\u5e74\uff0c\u5e76\u9010\u5e74\u9012\u589e2.5%\uff5e5.0%\u3002<\/p>\n
\u5168\u7403\u5e26\u72b6\u75b1\u75b9\u7684\u4f4f\u9662\u7387\u4e3a\uff082\uff5e25\uff09\/10\u4e07\u4eba\u5e74\uff0c\u6b7b\u4ea1\u7387\u4e3a\uff080.017\uff5e0.465\uff09\/10\u4e07\u4eba\u5e74\uff0c\u590d\u53d1\u73871%\uff5e 10%\u3002<\/p>\n
\u6211\u56fd\u226550\u5c81\u4eba\u7fa4\u5e26\u72b6\u75b1\u75b9\u53d1\u75c5\u7387\u4e3a\uff082.9\uff5e5.8\uff09\/1 000\u4eba\u5e74\uff0c\u5973\u6027\u7ec8\u8eab\u60a3\u75c5\u7387\uff083.94%\uff5e7.9%\uff09\u7565\u9ad8\u4e8e\u7537\u6027\uff082.86% \uff5e7.6%\uff09[1]<\/sup>\u3002<\/p>\n \u4e00.<\/p>\n \u4ec0\u4e48\u662f\u5e26\u72b6\u75b1\u75b9\uff1f<\/p>\n \u5e26\u72b6\u75b1\u75b9\uff08herpes zoster\uff09\u662f\u7531\u957f\u671f\u6f5c\u4f0f\u5728\u810a\u9ad3\u540e\u6839\u795e\u7ecf\u8282\u6216\u9885\u795e\u7ecf\u8282\u5185\u7684\u6c34\u75d8-\u5e26\u72b6\u75b1\u75b9\u75c5\u6bd2\uff08varicella-zoster virus\uff0cVZV\uff09\u7ecf\u518d\u6fc0\u6d3b\u5f15\u8d77\u7684\u611f\u67d3\u6027\u76ae\u80a4\u75c5\u3002<\/p>\n \u5e26\u72b6\u75b1\u75b9\u662f\u76ae\u80a4\u79d1\u5e38\u89c1\u75c5\uff0c\u9664\u76ae\u80a4\u635f\u5bb3\u5916\uff0c\u5e38\u4f34\u6709\u795e\u7ecf\u75c5\u7406\u6027\u75bc\u75db\uff0c\u591a\u89c1\u4e8e\u5e74\u9f84\u8f83\u5927\u3001\u514d\u75ab\u6291\u5236\u6216\u514d\u75ab\u7f3a\u9677\u7b49\u4eba\u7fa4\uff0c\u4e25\u91cd\u5f71\u54cd\u60a3\u8005\u751f\u6d3b\u8d28\u91cf\u3002<\/p>\n \u4e8c.<\/p>\n \u75c5\u56e0\u53ca\u53d1\u75c5\u673a\u5236<\/p>\n 1.\u75c5\u539f\u4f53\u7279\u70b9\u53ca\u81f4\u75c5\u673a\u5236\uff1a<\/p>\n VZV\u53ef\u7ecf\u98de\u6cab\u548c\uff08\u6216\uff09\u63a5\u89e6\u4f20\u64ad\uff0c\u539f\u53d1\u611f\u67d3\u4e3b\u8981\u5f15\u8d77\u6c34\u75d8\u3002\u5f53\u673a\u4f53\u62b5\u6297\u529b\u964d\u4f4e\u65f6\uff0c\u6f5c\u4f0f\u7684\u75c5\u6bd2\u88ab\u518d\u6fc0\u6d3b\u5f15\u8d77\u5e26\u72b6\u75b1\u75b9\u3002<\/p>\n 2.\u5e26\u72b6\u75b1\u75b9\u76f8\u5173\u6027\u75bc\u75db\u7684\u673a\u5236\uff1a<\/p>\n \u5e26\u72b6\u75b1\u75b9\u540e\u795e\u7ecf\u75db\uff08PHN\uff09\u5c5e\u4e8e\u5178\u578b\u7684\u795e\u7ecf\u75c5\u7406\u6027\u75bc\u75db\u3002<\/p>\n \u5916\u5468\u673a\u5236\uff1a\u53d7\u635f\u7684\u4f24\u5bb3\u6027\u611f\u53d7\u5668\u5f02\u5e38\u653e\u7535\u5bfc\u81f4\u5916\u5468\u654f\u5316\u3002<\/p>\n \u4e2d\u67a2\u673a\u5236\uff1a<\/p>\n \u2460\u810a\u9ad3\u80cc\u89d2\u795e\u7ecf\u5143\u7684\u654f\u611f\u6027\u589e\u9ad8\uff1b<\/p>\n \u2461\u810a\u9ad3\u6291\u5236\u6027\u795e\u7ecf\u5143\u7684\u529f\u80fd\u4e0b\u964d\uff1b<\/p>\n \u2462\u810a\u9ad3\u80cc\u89d2A\u03b2\u7ea4\u7ef4\u8131\u9ad3\u9798\uff0c\u4e0e\u90bb\u8fd1C\u7ea4\u7ef4\u5f62\u6210\u65b0\u7684\u7a81\u89e6\uff1b<\/p>\n \u2463\u810a\u9ad3\u80cc\u89d2\u4f24\u5bb3\u6027\u795e\u7ecf\u901a\u8def\u4ee3\u507f\u6027\u5f62\u6210\uff0c\u4f7f\u4e2d\u67a2\u5bf9\u75bc\u75db\u7684\u53cd\u5e94\u9608\u503c\u5927\u5927\u964d\u4f4e\u3002<\/p>\n \u4e09.<\/p>\n \u5e26\u72b6\u75b1\u75b9\u7684\u4e34\u5e8a\u8868\u73b0<\/p>\n 1.\u5178\u578b\u4e34\u5e8a\u8868\u73b0<\/p>\n \u2460\u524d\u9a71\u75c7\u72b6\uff1a\u53ef\u6709\u8f7b\u5ea6\u4e4f\u529b\u3001\u4f4e\u70ed\u3001\u98df\u6b32\u4e0d\u632f\u7b49\u5168\u8eab\u75c7\u72b6\uff0c\u60a3\u5904\u76ae\u80a4\u81ea\u89c9\u707c\u70ed\u611f\u6216\u795e\u7ecf\u75db\uff0c\u89e6\u4e4b\u6709\u660e\u663e\u7684\u75db\u89c9\u654f\u611f\uff0c\u4e5f\u53ef\u65e0\u524d\u9a71\u75c7\u72b6\u3002<\/p>\n \u2461\u76ae\u635f\u7279\u70b9\uff1a\u5178\u578b\u76ae\u635f\u8868\u73b0\u4e3a\u6cbf\u76ae\u8282\u5355\u4fa7\u5206\u5e03\u7684\u6210\u7c07\u6027\u6c34\u75b1\u4f34\u75bc\u75db\uff0c\u7814\u7a76\u663e\u793a\u597d\u53d1\u90e8\u4f4d\u4e3a\u808b\u95f4\u795e\u7ecf\uff0853%\uff09\u3001\u9888\u795e\u7ecf\uff0820%\uff09\u3001\u4e09\u53c9\u795e\u7ecf\uff0815%\uff09\u53ca\u8170\u9ab6\u90e8\u795e\u7ecf\uff0811%\uff09\u76f8\u5e94\u7684\u76ae\u8282\u3002<\/p>\n 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VZV\u6240\u81f4\u7684\u8111\u819c\u708e\/\u8111\u708e\uff1a\u7f8e\u56fd\u611f\u67d3\u75c5\u5b66\u4f1a\u6307\u5357\u63a8\u8350\u963f\u6614\u6d1b\u97e6\u6cbb\u7597\u672c\u75c5\uff0c\u8f7b\u4e2d\u5ea6\u75c5\u4f8b\u9759\u8109\u6ef4\u6ce810mg\/kg\u6bcf8 h 1\u6b21\uff0c\u8fde\u7eed\u6cbb\u759710\uff5e14d\uff0c\u800c\u4e25\u91cd\u75c5\u4f8b\u5e94\u6301\u7eed\u6cbb\u759714\uff5e21d\u3002<\/p>\n \u514d\u75ab\u529f\u80fd\u4f4e\u4e0b\u60a3\u8005\uff1a\u4e3b\u8981\u5305\u62ecHIV\/AIDS\u3001\u6076\u6027\u80bf\u7624\u3001\u5668\u5b98\u79fb\u690d\u3001\u5e72\u7ec6\u80de\u79fb\u690d\u60a3\u8005\u548c\u957f\u671f\u63a5\u53d7\u514d\u75ab\u6291\u5236\u5242\u6cbb\u7597\u60a3\u8005\u7b49\uff0c\u65e0\u8bba\u662f\u5c40\u9650\u578b\u8fd8\u662f\u64ad\u6563\u578b\u5e26\u72b6\u75b1\u75b9\uff0c\u5747\u63a8\u8350\u9759\u8109\u6ef4\u6ce8\u963f\u6614\u6d1b\u97e68\uff5e10 mg\/kg\u6bcf8 h 1\u6b21\uff0c\u7597\u7a0b7\uff5e10 d\uff0c\u6839\u636e\u75c5\u60c5\u9700\u8981\u53ef\u5ef6\u957f\u81f310\uff5e14 d\u3002<\/p>\n 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\u76ee\u524d\uff0c\u5168\u7403\u4e0a\u5e02\u7684\u5e26\u72b6\u75b1\u75b9\u75ab\u82d7\u4e3b\u8981\u5305\u62ec\u51cf\u6bd2\u6d3b\u75ab\u82d7\uff08ZVL\uff09\u548c\u91cd\u7ec4\u4e9a\u5355\u4f4d\u75ab\u82d7\uff08RZV\uff09\u4e24\u79cd\u30022020\u5e746\u6708\uff0cRZV\u5728\u6211\u56fd\u6b63\u5f0f\u4e0a\u5e02\uff0c\u63a8\u8350\u7528\u4e8e50\u5c81\u53ca\u4ee5\u4e0a\u514d\u75ab\u529f\u80fd\u6b63\u5e38\u7684\u4eba\u7fa4\u63a5\u79cd\u4ee5\u9884\u9632\u5e26\u72b6\u75b1\u75b9\u3002<\/p>\n \u6709\u5173RZV\u63a5\u79cd\u540e10\u5e74\u968f\u8bbf\u7814\u7a76\u53d1\u73b0\uff0c\u4f53\u6db2\u514d\u75ab\u6c34\u5e73\u662f\u63a5\u79cd\u524d\u76846.0\u500d\uff0c\u7ec6\u80de\u514d\u75ab\u6c34\u5e73\u662f\u63a5\u79cd\u524d\u76843.5\u500d\u3002\u5bf9\u75ab\u82d7\u6210\u5206\u8fc7\u654f\u6216\u4ee5\u524d\u63a5\u79cd\u540c\u7c7b\u75ab\u82d7\u65f6\u51fa\u73b0\u4e25\u91cd\u8fc7\u654f\u8005\u4e3a\u75ab\u82d7\u63a5\u79cd\u7981\u5fcc\u3002<\/p>\n 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\u201c\u5bb6\u6709\u4e00\u8001\uff0c\u5982\u6709\u4e00\u5b9d\u201d\uff0c\u5e0c\u671b\u6211\u4eec\u7684\u7236\u6bcd\u5728\u5e26\u72b6\u75b1\u75b9\u75ab\u82d7\u7684\u4fdd\u62a4\u4e0b\u5c3d\u4eab\u5929\u4f26\u4e4b\u4e50\uff01<\/p>\n \u53c2\u8003\u8d44\u6599<\/p>\n [1] \u300a\u4e2d\u56fd\u5e26\u72b6\u75b1\u75b9\u8bca\u7597\u4e13\u5bb6\u5171\u8bc6\uff082022\u7248\uff09\u300b<\/p>\n [2]\u4e2d\u56fd\u533b\u7597\u4fdd\u5065\u56fd\u9645\u4ea4\u6d41\u4fc3\u8fdb\u4f1a\u76ae\u80a4\u79d1\u5206\u4f1a,\u7b49.\u5e26\u72b6\u75b1\u75b9\u75ab\u82d7\u9884\u9632\u63a5\u79cd\u4e13\u5bb6\u5171\u8bc6[J].\u4e2d\u534e\u533b\u5b66\u6742\u5fd7,2022, 102(8):538-543.<\/p>\n [3]Schmader KE, Levin MJ, Gnann JW Jr, et al. Efficacy, safety, and tolerability of herpes zoster vaccine in persons aged 50\u201359 years. Clin Infect Dis 2012;54:922\u20138.<\/p>\n [4]\u4e2d\u75be\u63a7\u5468\u62a5Meiying You, Tianqi Wang, Miaomiao Wang, Wei Jiang, Jing Jiang, Xudong Li, Yuehua Hu, Dapeng Yin. Identifying the Optimal Age for Herpes Zoster Vaccination \u2014 Yichang City, Hubei Province, China, 2017\u20132019[J]. China CDC Weekly, 2022, 4(29): 631-634. doi: 10.46234\/ccdcw2022.137<\/p>\n [5]\u9093\u6167\u6770,\u5218\u82b3\u52cb.\u6211\u56fd\u5e26\u72b6\u75b1\u75b9\u6d41\u884c\u75c5\u5b66\u7279\u5f81\u53ca\u75ab\u82d7\u514d\u75ab\u89c4\u5212\u7814\u7a76\u8fdb\u5c55[J].\u4e2d\u56fd\u7ee7\u7eed\u533b\u5b66\u6559\u80b2,2021,13(19):135-138.<\/p>\n [6]\u51af\u5f55\u53ec\uff0c\u6768\u6d9b\uff0c\u738b\u6674\uff0c\u7b49.\u79d1\u5b66\u63a5\u79cd\u75ab\u82d7 \u964d\u4f4e\u611f\u67d3\u6027\u75be\u75c5\u98ce\u9669\u62a4\u536b\u8001\u5e74\u5065\u5eb7[J].\u4e2d\u534e\u533b\u5b66\u6742\u5fd7,2020,100(48):3821-3826.<\/p>\n DOI\uff1a10.3760\/cma.j.cn112137-20201020-02882<\/p>\n [7]\u75ab\u82d7\u8bf4\u660e\u4e66<\/p>\n","protected":false},"excerpt":{"rendered":" \u4f60\u7684\u7236\u6bcd\u662f\u5426\u63d0\u8d77\u8fc7\uff0c\u4ed6\u4eec\u66fe\u6bcf\u591c\u75db\u5f97\u7761\u4e0d\u7740\u89c9\uff1f \u4f60\u7684\u7237\u7237\u5976\u5976\u662f\u5426\u544a\u8bc9\u8fc7\u4f60\uff0c\u4ed6\u4eec\u66fe\u88ab … \u7ee7\u7eed\u9605\u8bfb