\u96cc\u6fc0\u7d20\u53d7\u4f53\uff08ER\uff09\/\u5b55\u6fc0\u7d20\u53d7\u4f53\uff08PR\uff09\u3001HER2\u68c0\u6d4b\u5728\u4e73\u817a\u764c\u60a3\u8005\u6cbb\u7597\u51b3\u7b56\u4e2d\u8d77\u7740\u5173\u952e\u6027\u4f5c\u7528\uff0c\u7ec6\u80deKi67\u9633\u6027\u6307\u6570\u4e0e\u4e73\u817a\u764c\u7ec4\u7ec7\u5b66\u5206\u7ea7\u3001\u751f\u5b58\u671f\u3001\u9884\u671f\u5316\u7597\u53cd\u5e94\u5bc6\u5207\u76f8\u5173\u3002\u8fd9\u56db\u9879\u514d\u75ab\u7ec4\u5316\u6807\u8bb0\u7269\u7ed3\u679c\u7684\u51c6\u786e\u5224\u8bfb\uff0c\u76f4\u63a5\u5173\u7cfb\u5230\u60a3\u8005\u4e0b\u4e00\u6b65\u7684\u6cbb\u7597\u65b9\u6848\u7684\u9009\u62e9\u3001\u9884\u540e\u53ca\u7597\u6548\u7684\u9884\u6d4b\u3002\u75c5\u7406\u533b\u5e08\u662f\u4e73\u817a\u764c\u8bca\u6cbb\u56e2\u961f\u4e2d\u975e\u5e38\u91cd\u8981\u7684\u4e00\u5458\uff0c\u9700\u8981\u5c06\u6bcf\u4e00\u4f8b\u80bf\u7624\u7684\u751f\u7269\u5b66\u7279\u5f81\u8fdb\u884c\u51c6\u786e\u89e3\u8bfb\uff0c\u5e2e\u52a9\u56e2\u961f\u7cbe\u51c6\u6cbb\u7597\u3002<\/p>\n
\u4e00\u3001\u4e73\u817a\u764c\u96cc\u3001\u5b55\u6fc0\u7d20\u53d7\u4f53\u514d\u75ab\u7ec4\u5316\u68c0\u6d4b\u7ed3\u679c\u7684\u5224\u8bfb<\/p>\n
1\u3001ER\u3001PR \u7684\u68c0\u6d4b\u9002\u5b9c\u4eba\u7fa4\uff1a<\/p>\n
\uff081\uff09\u6240\u6709\u65b0\u8bca\u65ad\u7684\u6d78\u6da6\u6027\u4e73\u817a\u764c\u75c5\u4f8b<\/p>\n
\uff082\uff09\u591a\u53d1\u6027\u4e73\u817a\u764c\u75c5\u4f8b\uff0c\u82e5\u7ec4\u7ec7\u5f62\u6001\u76f8\u4f3c\uff0c\u81f3\u5c11\u5e94\u5bf9\u5176\u4e2d\u4e00\u4e2a\u764c\u7076\u8fdb\u884c\u68c0\u6d4b\uff0c\u4ee5\u6700\u5927\u764c\u7076\u4e3a\u4f73\uff0c\u82e5\u7ec4\u7ec7\u5f62\u6001\u4e0d\u540c\uff0c\u5219\u5e94\u5206\u522b\u8fdb\u884c\u68c0\u6d4b<\/p>\n
\uff083\uff09\u6240\u6709\u590d\u53d1\u6216\u8f6c\u79fb\u7684\u4e73\u817a\u764c\u75c5\u4f8b\u5e94\u5c3d\u53ef\u80fd\u518d\u6b21\u68c0\u6d4b<\/p>\n
\uff084\uff09\u5efa\u8bae\u5bf9\u65b0\u8bca\u65ad\u7684\u539f\u4f4d\u764c(\u5305\u62ec\u5bfc\u7ba1\u539f\u4f4d\u764c\u548c\u5c0f\u53f6\u539f\u4f4d\u764c)\u75c5\u4f8b\u8fdb\u884c\u68c0\u6d4b<\/p>\n
\uff085\uff09\u65b0\u8f85\u52a9\u5316\u7597\u540e\u4ecd\u6709\u80bf\u7624\u6b8b\u7559\u7684\u75c5\u4f8b\u5efa\u8bae\u518d\u6b21\u68c0\u6d4b<\/p>\n
\uff086\uff09\u4e34\u5e8a\u63d0\u51fa\u9700\u8981\u8fdb\u884c\u68c0\u6d4b\u7684\u5176\u4ed6\u60c5\u51b5<\/p>\n
2\u3001\u67d3\u8272\u5bf9\u7167\u7684\u8bbe\u7acb\uff1a<\/p>\n
\u5e94\u5f53\u8bbe\u7acb\u9633\u6027\u5bf9\u7167\u548c\u9634\u6027\u5bf9\u7167\u3002<\/p>\n
\u5916\u5bf9\u7167\u53ef\u4ee5\u9009\u62e9\u5df2\u77e5\u660e\u786e\u7684\u9634\u6027\u548c\u9633\u6027\u8868\u8fbe\u7684\u5b50\u5bab\u5185\u819c\u7ec4\u7ec7\uff08\u56fe1\uff09\u6216\u4e73\u817a\u764c\u7ec4\u7ec7\u3002<\/p>\n
\u9633\u6027\u5185\u5bf9\u7167\u53ef\u9009\u62e9\u764c\u65c1\u6b63\u5e38\u4e73\u817a\u5bfc\u7ba1\u4e0a\u76ae\u7ec6\u80de\uff0c\u5176 ER\u3001PR \u67d3\u8272\u8868\u73b0\u4e3a\u5f3a\u5ea6\u4e0d\u4e00\u3002\u9634\u6027\u5185\u5bf9\u7167\u53ef\u9009\u62e9\u4e73\u817a\u7ec4\u7ec7\u4e2d\u7684\u808c\u4e0a\u76ae\u7ec6\u80de\u548c\u95f4\u8d28\u7ec6\u80de\uff0c\u5176\u4e0d\u8868\u8fbe ER\u3001PR\uff08\u56fe2-3\uff09\u3002<\/p>\n
\u56fe1<\/p>\n
\u56fe2<\/p>\n
\u56fe3<\/p>\n
3\u3001\u68c0\u6d4b\u65b9\u6cd5\u7684\u9009\u62e9\uff1a\u81ea\u52a8\u5316\u514d\u75ab\u7ec4\u7ec7\u5316\u5b66\u67d3\u8272\u7cfb\u7edf\u66f4\u6613\u8fbe\u5230\u6807\u51c6\u5316\uff08\u56fe4\uff09\u3002<\/p>\n
\u56fe4<\/p>\n
4\u3001\u67d3\u8272\u7ed3\u679c\u7684\u5206\u6790\u4e0e\u5224\u8bfb\uff1a<\/p>\n
\uff081\uff09ER\u3001PR \u9633\u6027\u7684\u4e34\u754c\u503c\uff1a<\/p>\n
ER\u3001PR \u80bf\u7624\u7ec6\u80de\u9633\u6027\u7387\u8fbe\u5230 1%\u65f6\u5c31\u4e0e\u4e34\u5e8a\u5185\u5206\u6ccc\u6cbb\u7597\u7684\u7597\u6548\u663e\u8457\u76f8\u5173\uff0c\u6307\u5357\u5efa\u8bae\u5c06 ER\u3001PR \u514d\u75ab\u7ec4\u7ec7\u5316\u5b66\u68c0\u6d4b\u7684\u9633\u6027\u9608\u503c\u5b9a\u4e3a\u22651%\u3002<\/p>\n
2019\u7248WHO\u7279\u522b\u5f3a\u8c03\uff1a\u5bf9\u4e8e\u6fc0\u7d20\u53d7\u4f53\u7684\u5224\u65ad\uff0c\u4f4e\u500d\u955c\u89c2\u5bdf\u53ef\u80fd\u4f1a\u9057\u6f0f\u8f83\u5f31\u7684\u67d3\u8272\uff0c\u5e94\u8be5\u8fdb\u4e00\u6b65\u5728\u9ad8\u500d\u955c\u4e0b\u4ed4\u7ec6\u89c2\u5bdf\uff0c\u4ee5\u9664\u5916\u4e34\u754c\u503c\uff081%~10%\u5f31\u9633\u6027\uff09\u3002<\/p>\n
\uff082\uff09\u539f\u4f4d\u764c\u7684 ER\u3001PR \u68c0\u6d4b\uff1a\u5efa\u8bae\u5bf9\u539f\u4f4d\u764c\u8fdb\u884c ER\u3001PR \u68c0\u6d4b\uff0c\u800c\u5bf9\u4e8e\u4f34\u6709\u539f\u4f4d\u764c\u6210\u5206\u7684\u6d78\u6da6\u6027\u764c\uff0c\u5e94\u62a5\u544a\u6d78\u6da6\u6027\u764c\u7684 ER\u3001PR \u72b6\u6001\uff0c\u53ef\u5728\u5907\u6ce8\u4e2d\u8bf4\u660e\u539f\u4f4d\u764c\u7684 ER\u3001PR \u72b6\u6001\u3002<\/p>\n
\uff083\uff09\u5bf9\u7167\u67d3\u8272\u7684\u5224\u8bfb\uff1a\u5728\u5224\u8bfb\u65f6\u5e94\u9996\u5148\u68c0\u67e5\u5404\u5bf9\u7167\u7684\u67d3\u8272\u60c5\u51b5\uff0c\u5982\u679c\u4e0d\u7b26\u5408\u9884\u671f\u7ed3\u679c\uff0c\u6b64\u75c5\u4f8b\u7684 ER\u3001PR \u7ed3\u679c\u5e94\u62a5\u544a\u4e3a\u65e0\u6cd5\u5224\u8bfb\u3002<\/p>\n
\uff084\uff09\u68c0\u6d4b\u7ed3\u8bba\uff1a\u9633\u6027\u3001\u9634\u6027\u3001\u65e0\u6cd5\u5224\u8bfb\u3002<\/p>\n
\u8bc4\u4f30\u6574\u5f20\u5207\u7247\u4e2d\u9633\u6027\u67d3\u8272\u7684\u80bf\u7624\u7ec6\u80de\u5360\u6240\u6709\u80bf\u7624\u7ec6\u80de\u7684\u6bd4\u4f8b<\/p>\n
\u2460\u22651%\u7684\u80bf\u7624\u7ec6\u80de\u6838\u5448\u73b0\u4e0d\u540c\u7a0b\u5ea6\u7684\u7740\u8272\u65f6\u4e3a\u9633\u6027;<\/p>\n
\u2461<1%\u7684\u80bf\u7624\u7ec6\u80de\u6838\u5448\u73b0\u4e0d\u540c\u7a0b\u5ea6\u7684\u7740\u8272\u6216\u5b8c\u5168\u65e0\u7740\u8272\u4e3a\u9634\u6027;<\/p>\n
\u2462\u68c0\u6d4b\u524d\u5904\u7406\u6216\u68c0\u6d4b\u6b65\u9aa4\u4e0d\u7b26\u5408\u89c4\u5b9a\uff0c\u6216\u67d3\u8272\u5b9a\u4f4d\u4e0d\u5728\u7ec6\u80de\u6838\uff0c\u6216\u5bf9\u7167\u672a\u51fa\u73b0\u9884\u671f\u7ed3\u679c\uff0c\u6216\u9634\u6027\u67d3\u8272\u4f46\u6807\u672c\u4e2d\u7f3a\u4e4f\u5185\u5bf9\u7167\u7ec4\u7ec7\uff0c\u89c6\u4e3a\u65e0\u6cd5\u5224\u8bfb\u3002<\/p>\n
\uff085\uff09\u9633\u6027\u67d3\u8272\u5f3a\u5ea6\uff1a\u5305\u62ec\u5f31\u3001\u4e2d \u3001\u5f3a\u3002\u5982\u679c\u540c\u4e00\u5f20\u5207\u7247\u4e2d\u80bf\u7624\u7ec6\u80de\u7684\u67d3\u8272\u5f3a\u5ea6\u5b58\u5728\u5dee\u5f02 \uff0c\u53ef\u91c7\u7528\u5f31-\u4e2d\u7b49\uff0c\u6216\u4e2d\u7b49-\u5f3a\u7684\u62a5\u544a\u65b9\u5f0f\u3002\uff08\u56fe5-6\uff09<\/p>\n
\u56fe5<\/p>\n
\u56fe6<\/p>\n
\uff086\uff09\u9633\u6027\u80bf\u7624\u7ec6\u80de\u7684\u767e\u5206\u6bd4\uff1a\u6574\u5f20\u5207\u7247\u9633\u6027\u67d3\u8272\u7ec6\u80de\u5360\u6240\u6709\u80bf\u7624\u7ec6\u80de\u7684\u767e\u5206\u6bd4\uff0c\u5efa\u8bae10%~100%\u9633\u6027\u7740\u8272\u65f6\u4ee5\u4ee5\u6bcf10%\u4e3a\u4e00\u4e2a\u7b49\u7ea7\u3002<\/p>\n
\uff087\uff09\u62a5\u544a\u5185\u5bb9\uff1a\u68c0\u6d4b\u7ed3\u8bba\uff08\u9633\u6027\u3001\u9634\u6027\u3001\u65e0\u6cd5\u5224\u8bfb\uff09\uff0c\u9633\u6027\u5e94\u62a5\u544a\u67d3\u8272\u5f3a\u5ea6\u548c\u9633\u6027\u80bf\u7624\u7ec6\u80de\u7684\u767e\u5206\u6bd4\u3002\uff08\u56fe7-8\uff09<\/p>\n
\u56fe7 ER\uff08\u4e2d-\u5f3a\u9633\u6027\uff0c\u7ea680%\uff09<\/p>\n
\u56fe8 PR\uff08\u4e2d-\u5f3a\u9633\u6027\uff0c\u7ea660%\uff09<\/p>\n
\uff088\uff09\u9700\u8981\u91cd\u590d\u68c0\u6d4b\u7684\u60c5\u51b5\uff1a<\/p>\n
\u2460ER-\/PR \u7684\u75c5\u4f8b\uff1b<\/p>\n
\u24611\u7ea7\u7684\u6d78\u6da6\u6027\u5bfc\u7ba1\u764c\u3001\u7ecf\u5178\u578b\u6d78\u6da6\u6027\u5c0f\u53f6\u764c\u3001\u5c0f\u7ba1\u764c\u3001\u9ecf\u6db2\u764c\u3001\u5b9e\u6027\u4e73\u5934\u72b6\u764c\u7b49\u901a\u5e38\u4e3a ER \u9633\u6027\uff0c\u5982\u68c0\u6d4b\u7ed3\u679c\u4e3a\u9634\u6027\uff0c\u9700\u8981\u6838\u5b9e\u8bca\u65ad\u6216\u91cd\u65b0\u68c0\u6d4b\uff1b<\/p>\n
\u2462\u5bf9\u4e8e\u5404\u79cd\u539f\u56e0\u5bfc\u81f4\u7684\u65e0\u6cd5\u5224\u8bfb\u7684\u75c5\u4f8b\u5e94\u91cd\u65b0\u68c0\u6d4b;<\/p>\n
\u2463\u5efa\u8bae\u5bf9\u7ed3\u679c\u4e3a 1%\u4e34\u754c\u503c\u9644\u8fd1\u7684\u75c5\u4f8b\u53ca\u5f25\u6f2b\u5f31\u9633\u6027\u7684\u75c5\u4f8b\u91cd\u65b0\u68c0\u6d4b\u3002<\/p>\n
\u4e8c\u3001\u4e73\u817a\u764cHER2\u514d\u75ab\u7ec4\u5316\u68c0\u6d4b\u7ed3\u679c\u7684\u5224\u8bfb<\/p>\n
1\u3001HER2\u514d\u75ab\u7ec4\u5316\u68c0\u6d4b\u7ed3\u679c\u7684\u5224\u8bfb\u6807\u51c6\uff1a\uff08\u56fe9-12\uff09<\/p>\n
2019\u7248\u4e73\u817a\u764cHER2\u68c0\u6d4b\u6307\u5357<\/p>\n<\/p>\n
\u56fe9 HER2\uff080\uff09<\/p>\n
\u56fe10 HER2\uff081 \uff09<\/p>\n
\u56fe11 HER2\uff082 \uff09<\/p>\n
\u56fe12 HER2\uff083 \uff09 <\/p>\n
\u800c\u6307\u5357\u4e2d\u5bf9\uff1c10%\u7684\u6d78\u6da6\u764c\u7ec6\u80de\u5448\u73b0\u5f31\u81f3\u4e2d\u7b49\u5f3a\u5ea6\u7684\u5b8c\u6574\u7ec6\u80de\u819c\u67d3\u8272\u53ca\uff1e10%\u7684\u6d78\u6da6\u764c\u7ec6\u80de\u5448\u73b0\u4e2d-\u5f3a\u7684\u4e0d\u5b8c\u6574\u7684\u7ec6\u80de\u819c\u67d3\u8272\u7b49\u8fd9\u4e9b\u60c5\u51b5\u6ca1\u6709\u8bf4\u660e\u5982\u4f55\u5224\u8bfb\uff0c\u57282022\u5e74\u82f1\u56fd\u7684HER2\u68c0\u6d4b\u6307\u5357\u4e2d\u5bf9\uff1c10%\u7684\u6d78\u6da6\u764c\u7ec6\u80de\u5448\u4e2d\u7b49\u5f3a\u5ea6\u7684\u5b8c\u6574\u7ec6\u80de\u819c\u67d3\u8272\u5224\u8bfb\u4e3aIHC 2 \uff1b2014\u7248\u6cd5\u56fd\u6307\u5357\u4e2d\u5c06\uff1e10%\u7684\u6d78\u6da6\u764c\u7ec6\u80de\u5448\u73b0\u4e2d-\u5f3a\u7684\u4e0d\u5b8c\u6574\u7684\u7ec6\u80de\u819c\u67d3\u8272\u5224\u8bfb\u4e3aIHC 2 \u3002<\/p>\n
2\u3001HER2\u5f02\u8d28\u6027\u8868\u8fbe<\/p>\n
\uff081\uff092009\u5e74\u7f8e\u56fd\u75c5\u7406\u533b\u5e08\u5b66\u9662\u6307\u5357\u89c4\u8303\u4e86HER2\u5f02\u8d28\u6027\u7684\u5b9a\u4e49\uff1a\u540c\u4e00\u80bf\u7624\u4e2d\u51fa\u73b05%~50%\u7684\u80bf\u7624\u7ec6\u80de HER2\/CEP17\u6bd4\u503c>2.2\u3002\u9700\u8981\u660e\u786e\u7684\u662f\uff0c\u5982\u679c\u51fa\u73b0\uff1e10%\u80bf\u7624\u7ec6\u80de\u5448\u73b0\u5b8c\u6574\u3001\u5f3a\u7684\u80de\u819c\u7740\u8272\u5373\u5224\u8bfb\u4e3a HER2\u9633\u6027\uff0c\u5982\u679c\u4e0d\u8db310%\u7684\u60c5\u51b5\u5219\u8003\u8651\u4e3a\u4e34\u754c\u503c\uff082 \uff09\uff0c\u5efa\u8bae\u539f\u4f4d\u6742\u4ea4\u68c0\u6d4b\u3002\u5982\u679c\u539f\u4f4d\u6742\u4ea4\u4e5f\u652f\u6301HER2\u7684\u5f02\u8d28\u6027\uff0c\u90a3\u4e483 \u533a\u57df\u9700\u8981\u5355\u72ec\u8ba1\u6570\uff0c\u5e76\u6807\u6ce8HER2\u9633\u6027\u7ec6\u80de\u5360\u6574\u4e2a\u80bf\u7624\u7684\u6bd4\u4f8b\u3002<\/p>\n
2019\u7248\u4e73\u817a\u764cHER2\u68c0\u6d4b\u6307\u5357\u4e2d\u5b9a\u4e49\uff1a\u514d\u75ab\u7ec4\u5316\u68c0\u6d4b\u5177\u6709\u5f3a\u800c\u5b8c\u6574\u819c\u67d3\u8272\u7684\u80bf\u7624\u7ec6\u80de <10%\u3002<\/p>\n
\uff082\uff09\u226410%\u7684\u6d78\u6da6\u764c\u7ec6\u80de\u5448\u73b0\u5f3a\u800c\u5b8c\u6574\u7684\u7ec6\u80de\u819c\u67d3\u8272\uff0c\u5224\u8bfb\u4e3a2 \uff0c\u5efa\u8bae\u539f\u4f4d\u6742\u4ea4\u68c0\u6d4b\u3002<\/p>\n
\uff083\uff09\u5efa\u8bae\u5bf9\u4e8eHER2\u5f02\u8d28\u6027\u8868\u8fbe\u7684\u75c5\u4f8b\uff0c\u8bf4\u660e\u201c HER2 \u72b6\u6001\u5b58\u5728\u5f02\u8d28\u6027\u201d\uff0c\u5e76\u9700\u63cf\u8ff0\u6807\u672c\u67d3\u8272\u60c5\u51b5\uff08\u4e3b\u8981\u6210\u5206\u548c\u6b21\u8981\u6210\u5206\uff09\u3002<\/p>\n
\uff084\uff09\u9488\u5bf9\u5f02\u8d28\u6027\u75c5\u4f8b\uff0c\u9664\u4e86\u4e86\u89e3\u539f\u53d1\u7076\u7684 HER2 \u72b6\u6001\u4ee5\u5916\uff0c\u5982\u679c\u5b58\u5728\u8f6c\u79fb\u7076\uff0c\u5e94\u589e\u52a0\u8f6c\u79fb\u6210\u5206\u7684\u68c0\u6d4b\u3002<\/p>\n
3\u3001\u6d78\u6da6\u6027\u5fae\u4e73\u5934\u72b6\u764c\u7684HER2\u514d\u75ab\u7ec4\u5316\u5224\u8bfb<\/p>\n
\uff081\uff09\u5728\u4e73\u817a\u6d78\u6da6\u6027\u5fae\u4e73\u5934\u72b6\u764c\u548c\u90e8\u5206\u6709\u5206\u6ccc\u73b0\u8c61\u7684\u4e73\u817a\u764c\u4e2d\uff0c\u5e38\u5448\u7279\u6b8a\u7684\u57fa\u5e95\u53ca\u4fa7\u819cU\u578b\u67d3\u8272\u6a21\u5f0f\u3002\uff08\u56fe13-14\uff09<\/p>\n
\uff082\uff09\u6d78\u6da6\u6027\u5fae\u4e73\u5934\u72b6\u764cU\u578b\u67d3\u8272\u6a21\u5f0f\uff0c\u82e5HER2\u5448\u73b0\u5f31-\u4e2d\u7b49\u5f3a\u5ea6\u7684\u7ec6\u80de\u819c\u67d3\u8272\uff0c\u5e94\u5224\u4e3a 2 \uff0c\u5e76\u9700\u8981\u884c\u539f\u4f4d\u6742\u4ea4\u68c0\u6d4b\u8fdb\u4e00\u6b65\u660e\u786eHER2\u72b6\u6001\u3002\u82e5\u6d78\u6da6\u764c\u7684\u7ec6\u80de\u819c\u5df2\u5448\u5f88\u6df1\u7684\u68d5\u8910\u8272U\u578b\u67d3\u8272\uff0c\u53ef\u7b49\u540c\u4e8e\u5b8c\u6574\u7684\u7ec6\u80de\u819c\u67d3\u8272\u3002<\/p>\n
\u56fe13 \u6d78\u6da6\u6027\u5fae\u4e73\u5934\u72b6\u764c<\/p>\n
\u56fe14 HER2\u57fa\u5e95\u53ca\u4fa7\u819cU\u578b\u67d3\u8272\u6a21\u5f0f<\/p>\n
4\u3001\u4e73\u817a\u5fae\u6d78\u6da6\u6027\u764c\u7684HER2\u68c0\u6d4b\uff08\u56fe15-16\uff09<\/p>\n
\uff081\uff09\u4e73\u817a\u5fae\u6d78\u6da6\u6027\u764c\u7684\u5b9a\u4e49\u4e3a\u6d78\u6da6\u7076\u6700\u5927\u5f84\u22641 mm\u3002<\/p>\n
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\uff083\uff09\u867d\u7136HER2\u9633\u6027\u5fae\u6d78\u6da6\u764c\u7684\u6cbb\u7597\u539f\u5219\u5c1a\u5b58\u4e89\u8bae\uff0c\u4f46\u75c5\u7406\u533b\u5e08\u5e94\u5c3d\u53ef\u80fd\u62a5\u544a\u5fae\u6d78\u6da6\u764c\u7684HER2\u72b6\u6001\u3002<\/p>\n
\uff084\uff09\u5fae\u6d78\u6da6\u764c\u80bf\u7624\u7ec6\u80de\u8fc7\u5c11\uff0c\u5728HE\u5207\u7247\u4e0a\u6709\uff0cIHC\u5207\u7247\u4e0a\u5df2\u4e0d\u660e\u663e\uff0c\u75c5\u7406\u533b\u5e08\u53ef\u4ee5\u5907\u6ce8\uff1a\u6d78\u6da6\u764c\u7ec6\u80de\u592a\u5c11\uff0c\u96be\u4ee5\u8bc4\u4f30\u5176 HER2 IHC \u72b6\u6001\uff1b\u539f\u4f4d\u6742\u4ea4\u68c0\u6d4b\u9700\u8981\u8ba1\u6570\u81f3\u5c11 20 \u4e2a\u7ec6\u80de\uff0c\u5bf9\u4e8e\u7ec6\u80de\u6570\u91cf\u8fc7\u5c11\u7684\u5fae\u6d78\u6da6\u7076\u4e0d\u5b9c\u884c\u539f\u4f4d\u6742\u4ea4\u68c0\u6d4b\u3002<\/p>\n
\u56fe15 p63<\/p>\n
\u56fe16 HER2<\/p>\n
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\u63a8\u8350\u91c7\u7528\u6574\u5f20\u5207\u7247\u4e0e\u70ed\u70b9\u533a\u76f8\u7ed3\u5408\u7684\u65b9\u6cd5\u8bc4\u4f30\uff1a<\/p>\n
\uff081\uff09\u626b\u63cf\u6574\u4e2a\u5207\u7247\uff0c\u81f3\u5c11\u9009\u62e93\u4e2a\u4ee5\u4e0a\u7684\u9ad8\u500d\u955c\uff08\u00d7400\uff09\u4e0b\u7684\u4ee3\u8868\u6027\u533a\u57df\u8ba1\u6570\uff1b<\/p>\n
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\u56fe17 Ki67<\/p>\n
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