{"id":56567,"date":"2025-08-31T05:11:27","date_gmt":"2025-08-31T05:11:27","guid":{"rendered":"http:\/\/zydq.1006ss.com\/?p=56567"},"modified":"2025-08-31T05:11:27","modified_gmt":"2025-08-31T05:11:27","slug":"%e7%94%9f%e9%85%ae%e6%88%96%e6%98%af%e4%b8%80%e7%a7%8d%e4%bf%83%e8%a1%b0%e8%80%81%e9%a5%ae%e9%a3%9f%ef%bc%81cell%e5%ad%90%e5%88%8a%ef%bc%9a%e7%94%9f%e9%85%ae%e9%a5%ae%e9%a3%9f%e5%8a%a0%e9%80%9f","status":"publish","type":"post","link":"http:\/\/zydq.1006ss.com\/?p=56567","title":{"rendered":"\u751f\u916e\u6216\u662f\u4e00\u79cd\u4fc3\u8870\u8001\u996e\u98df\uff01Cell\u5b50\u520a\uff1a\u751f\u916e\u996e\u98df\u52a0\u901f\u96c4\u6027\u8870\u8001\uff0c\u96cc\u6027\u5219\u56e0\u96cc\u6fc0\u7d20\u514d\u53d7\u5f71\u54cd"},"content":{"rendered":"

\u751f\u916e\u996e\u98df\u662f\u4e00\u79cd\u9ad8\u8102\u80aa\u3001\u4f4e\u78b3\u6c34\u5316\u5408\u7269\u7684\u996e\u98df\u6a21\u5f0f\uff0c\u901a\u8fc7\u8bf1\u5bfc\u916e\u4f53\u751f\u6210\u6765\u66ff\u4ee3\u8461\u8404\u7cd6\u4f5c\u4e3a\u80fd\u91cf\u6765\u6e90\u3002<\/p>\n

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2025\u5e747\u670817\u65e5\uff0c\u7f8e\u56fd\u5fb7\u514b\u8428\u65af\u5927\u5b66\u7814\u7a76\u56e2\u961f\u5728’ Cell Reports ‘\u671f\u520a\u4e0a\u53d1\u8868\u4e86\u4e00\u7bc7\u9898\u4e3a’ Divergent sex-specific effects on a ketogenic diet\uff1aMale\uff0cbut not female\uff0cmice exhibit oxidative stress and cellular senescence ‘\u7684\u7814\u7a76\u8bba\u6587\u3002<\/p>\n

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\u603b\u4e4b\uff0c\u8fd9\u9879\u7814\u7a76\u4e0d\u4ec5\u63ed\u793a\u4e86\u751f\u916e\u996e\u98df\u7684\u6027\u522b\u5dee\u5f02\uff0c\u8fd8\u8868\u660e\u96cc\u6fc0\u7d20\u5728\u62b5\u6297\u6c27\u5316\u5e94\u6fc0\u548c\u7ec6\u80de\u8870\u8001\u4e2d\u7684\u5173\u952e\u4f5c\u7528\u3002\u7814\u7a76\u4eba\u5458\u8868\u793a\uff0c\u672a\u6765\u5728\u5236\u5b9a\u751f\u916e\u996e\u98df\u65b9\u6848\u65f6\uff0c\u5e94\u8003\u8651\u6027\u522b\u5dee\u5f02\u548c\u6fc0\u7d20\u72b6\u6001\uff0c\u4ee5\u51cf\u5c11\u6f5c\u5728\u7684\u98ce\u9669\u3002<\/p>\n

\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0c\u6b64\u524d\uff0c\u540c\u4e00\u7814\u7a76\u56e2\u961f\u5728’ Science Advances ‘\u671f\u520a\u4e0a\u53d1\u8868\u7684\u4e00\u7bc7\u7814\u7a76\u4e5f\u63ed\u793a\u4e86\u751f\u916e\u996e\u98df\u4f1a\u52a0\u901f\u8870\u8001\u3002<\/p>\n

\u56fe\uff1a\u8bba\u6587\u622a\u56fe<\/p>\n

2024\u5e745\u6708\uff0c’ Science Advances ‘\u671f\u520a\u4e0a\u53d1\u8868\u4e86\u4e00\u7bc7\u9898\u4e3a’ Ketogenic diet induces p53-dependent cellular senescence in multiple organs ‘\u7684\u7814\u7a76\u8bba\u6587\u3002<\/p>\n

\u7814\u7a76\u663e\u793a\uff0c\u751f\u916e\u996e\u98df\u4f1a\u8bf1\u5bfc\u591a\u4e2a\u5668\u5b98\u7684p53\u4f9d\u8d56\u6027\u7ec6\u80de\u8870\u8001\uff0c\u957f\u671f\u6301\u7eed\u7684\u751f\u916e\u996e\u98df\u53ef\u80fd\u4f1a\u5bfc\u81f4\u6b63\u5e38\u7ec4\u7ec7\u4e2d\u7684\u7ec6\u80de\u8870\u8001\uff0c\u5c24\u5176\u662f\u5fc3\u810f\u548c\u80be\u810f\u3002<\/p>\n

\u7136\u800c\uff0c\u95f4\u6b47\u6027\u751f\u916e\u996e\u98df\u5219\u6ca1\u6709\u8868\u73b0\u51fa\u56e0\u7ec6\u80de\u8870\u8001\u800c\u4ea7\u751f\u7684\u4efb\u4f55\u4fc3\u708e\u4f5c\u7528\uff0c\u8868\u660e\u95f4\u6b47\u6027\u751f\u916e\u996e\u98df\u53ef\u80fd\u4f1a\u589e\u5f3a\u751f\u916e\u996e\u98df\u7684\u6709\u76ca\u6548\u679c\u3002<\/p>\n

\u53e6\u5916\uff0c\u751f\u916e\u996e\u98df\u8fd8\u4e0e\u4fc3\u8fdb\u764c\u75c7\u8f6c\u79fb\u6709\u5173\u3002<\/p>\n

2024\u5e746\u6708\uff0c\u54e5\u4f26\u6bd4\u4e9a\u5927\u5b66\u987e\u4f1f\u56e2\u961f\u5728’ Science Advances ‘\u671f\u520a\u4e0a\u53d1\u8868\u4e86\u4e00\u7bc7\u7814\u7a76\uff0c\u7ed3\u679c\u663e\u793a\uff0c\u751f\u916e\u996e\u98df\u867d\u7136\u53ef\u4ee5\u6291\u5236\u539f\u53d1\u6027\u80bf\u7624\u751f\u957f\uff0c\u4f46\u4f1a\u4fc3\u8fdb\u764c\u75c7\u8f6c\u79fb\uff0c\u5e76\u63ed\u793a\u4e86\u4fc3\u8fdb\u764c\u75c7\u8f6c\u79fb\u7684\u673a\u5236\u3002\u7814\u7a76\u6307\u51fa\uff0c\u5bf9\u4eba\u7c7b\u764c\u75c7\u60a3\u8005\u800c\u8a00\uff0c\u751f\u916e\u996e\u98df\u53ef\u80fd\u5b58\u5728\u5065\u5eb7\u98ce\u9669\u3002<\/p>\n

\u56fe\uff1a\u8bba\u6587\u622a\u56fe<\/p>\n

\u53c2\u8003\u6587\u732e\uff1a<\/p>\n

https:\/\/\/10.1016\/j.celrep.2025.116026<\/p>\n

https:\/\/www.\/doi\/10.1126\/sciadv.ado1463<\/p>\n

https:\/\/www.\/doi\/10.1126\/sciadv.adm9481<\/p>\n

\u58f0\u660e\uff1a\u672c\u6587\u4ec5\u505a\u5b66\u672f\u5206\u4eab\uff0c\u4e0d\u6784\u6210\u4efb\u4f55\u5efa\u8bae\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

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