\u6865\u672c\u75c5\u3001\u6216\u6865\u672c\u6c0f\u7532\u72b6\u817a\u708e\u3001\u6162\u6027\u6dcb\u5df4\u7ec6\u80de\u6027\u7532\u72b6\u817a\u708e\uff0c\u662f\u4e00\u79cd\u5e38\u89c1\u7684\u7532\u72b6\u817a\u75be\u75c5\uff0c\u76ee\u524d\u8ba4\u4e3a\u662f\u81ea\u8eab\u514d\u75ab\u6027\u539f\u56e0\u5f15\u8d77\u7684\u3002\u6865\u672c\u75c5\u7531\u65e5\u672c\u5b66\u8005\u6865\u672c\u7b561912\u5e74\u9996\u5148\u62a5\u9053\u3002\u4ee5\u7532\u72b6\u817a\u5f25\u6f2b\u6027\u80bf\u5927\u3001\u7532\u72b6\u817a\u8fc7\u6c27\u5316\u7269\u9176\u6297\u4f53(TPOAb)\u3001\u7532\u72b6\u817a\u7403\u86cb\u767d\u6297\u4f53(TgAb)\u5347\u9ad8\u4e3a\u4e3b\u8981\u4e34\u5e8a\u7279\u5f81,\u6dcb\u5df4\u7ec6\u80de\u6d78\u6da6\u7532\u72b6\u817a\u4e3a\u4e3b\u8981\u75c5\u7406\u7279\u5f81\u3002<\/p>\n<\/p>\n
\u3010\u6865\u672c\u4e0e\u6865\u672c\u6c0f\u7532\u72b6\u817a\u708e\u3011<\/p>\n<\/p>\n
\u6865\u672c\u7b56(Hakaru Hashimoto)1881\u5e745\u67085\u65e5\u751f\u4e8e\u65e5\u672c\u4e09\u91cd\u53bf\u6851\u540d\u5e02\u4f0a\u8d3a\u753a\u30021907\u5e74\u6bd5\u4e1a\u4e8e\u4eac\u90fd\u5e1d\u56fd\u5927\u5b66\u798f\u5188\uff08Fukuoka\uff09\u533b\u5b66\u9662\uff08\u73b0\u4e5d\u5dde\u5927\u5b66\u533b\u5b66\u9662\uff09\u3002\u5f53\u65f6\u7684\u798f\u5188\u533b\u5b66\u9662\u4f5c\u4e3a\u4eac\u90fd\u5927\u5b66\u533b\u5b66\u9662\u5206\u9662\u521b\u7acb\u4e8e1900\u5e74\u3002\u9996\u4efb\u6821\u957fOhmori\u6559\u6388\u9080\u8bf7\u4e86\u4e3b\u8981\u6765\u81ea\u4e1c\u4eac\u5927\u5b66\u7684\u5e74\u8f7b\u5b66\u8005\u62c5\u4efb\u7cfb\u4e3b\u4efb\uff0c\u5e76\u4ece\u65e5\u672c\u5404\u5730\u7684\u9ad8\u4e2d\u751f\u4e2d\u5bfb\u627e\u6709\u62b1\u8d1f\u7684\u5b66\u751f\uff0c\u5171\u540c\u6210\u4e3a\u5927\u5b66\u7684\u57fa\u7840\uff0c\u56e0\u6b64\uff0c\u5e08\u751f\u5173\u7cfb\u975e\u5e38\u878d\u6d3d\u3002<\/p>\n
\u5927\u5b66\u6bd5\u4e1a\u540e\uff0c\u6865\u672c\u8fdb\u5165\u7b2c\u4e00\u5916\u79d1\u5b66\u7cfb\u3002\u5f53\u65f6\u7684\u7cfb\u4e3b\u4efb\u4e09\u5b85\uff08Hayari Miyake\uff09\u6559\u6388\u662f\u4e00\u4f4d\u4f18\u79c0\u7684\u5916\u79d1\u533b\u751f\uff0c\u4e13\u95e8\u4ece\u4e8b\u5185\u810f\u548c\u764c\u75c7\u624b\u672f\u3002\u4ed6\u66fe\u53d1\u73b0\u4e00\u79cd\u79f0\u4e3a\u201c\u5341\u4e8c\u6307\u80a0\u79fb\u52a8\u75c7\u201d\uff08Das prim\u00e4re Duodenummobile\uff09\u7684\u65b0\u75be\u75c5\u3002\u4e09\u5b85\u5e08\u4ece\u4e1c\u4eac\u5927\u5b66Scriba\u6559\u6388\uff0c\u66fe\u5148\u540e\u4e24\u6b21\u8d74\u5fb7\u56fd\u8ddf\u968f\u7ef4\u4e5f\u7eb3\u5927\u5b66\u5fb7\u56fd\u8179\u90e8\u5916\u79d1\u4e4b\u7236\u6bd5\u7f57\u65af\u6770\u51fa\u7684\u5b66\u751f\u4e4b\u4e00Mikulicz\u5b66\u4e60\u3002Mikulicz\u66fe\u63cf\u8ff0\u4e00\u79cd\u7531\u6dcb\u5df4\u7ec4\u7ec7\u8fc7\u5ea6\u751f\u957f\u5f15\u8d77\u7684\u6cea\u817a\u548c\u553e\u6db2\u817a\u7684\u5bf9\u79f0\u80bf\u80c0\uff0c\u73b0\u79f0\u4e3aMikulicz\u75c5\u3002<\/p>\n<\/p>\n
\u5e08\u627f\u5173\u7cfb\u89c1\u56fe<\/p>\n
1912\u5e74\uff0c30\u5c81\u7684\u6865\u672c\u5728\u5fb7\u56fd\u4e34\u5e8a\u5916\u79d1\u6742\u5fd7\u300aArchivf\u00fcr Klinische Chirurgie\u300b\u4e0a\u62a5\u9053\u4e86\u4e00\u79cd\u65b0\u75be\u75c5\u3002\u4ed6\u7684\u8bba\u6587\u753130\u9875\u548c5\u5f20\u63d2\u56fe\u7ec4\u6210\uff0c\u8ba8\u8bba\u4e86\u53d6\u81ea4\u540d\u5987\u5973\u7684\u7532\u72b6\u817a\u7ec4\u7ec7\u6837\u672c\uff0c\u75c5\u7406\u7279\u5f81\u663e\u793a\u5f25\u6f2b\u6027\u6dcb\u5df4\u7ec6\u80de\u6d78\u6da6\u4f34\u751f\u53d1\u4e2d\u5fc3\uff0c\u7ea4\u7ef4\u5316\uff0c\u5b9e\u8d28\u840e\u7f29\u548c\u4e00\u4e9b\u7532\u72b6\u817a\u6ee4\u6ce1\u7ec6\u80de\u55dc\u9178\u6027\u6539\u53d8\u3002\u7ec4\u7ec7\u5b66\u4e0a\u4e0eMikulicz\u75c5\u76f8\u4f3c\u3002\u4ed6\u81ea\u4fe1\u5730\u8868\u793a\uff0c\u4ed6\u53d1\u73b0\u4e86\u4e00\u79cd\u65b0\u7684\u75be\u75c5\uff0c\u5c06\u5176\u547d\u540d\u4e3a\u201c\u6dcb\u5df4\u7624\u6837\u7532\u72b6\u817a\u80bf\u201d\uff08struma lymphomatosa\uff09\u3002<\/p>\n<\/p>\n
\u540c\u5e74\uff0c\u6865\u672c\u6765\u5230\u54e5\u5ef7\u6839\u5927\u5b66\u5e08\u4ece\u5fb7\u56fd\u8457\u540d\u75c5\u7406\u5b66\u5bb6\u8003\u592b\u66fc\uff08Kaufmann\uff09\uff0c\u8fdb\u884c\u4e86\u4e24\u5e74\u7684\u80be\u7ed3\u6838\u7814\u7a76\u30021914\u5e74\u7b2c\u4e00\u6b21\u4e16\u754c\u5927\u6218\u7206\u53d1\u65f6\u56de\u5230\u65e5\u672c\u30021916\u5e74\uff0c\u4ed6\u63a5\u7ba1\u4e86\u5bb6\u65cf\u751f\u610f\u3002\u7531\u4e8e\u6bd5\u4e1a\u4e8e\u5e1d\u56fd\u5927\u5b66\u5e76\u5728\u56fd\u5916\u6df1\u9020\uff0c\u4ed6\u7684\u540d\u58f0\u5f88\u5feb\u4f20\u904d\u4e86\u5168\u56fd\u3002\u5728\u4ed6\u7684\u804c\u4e1a\u751f\u6daf\u4e2d\uff0c\u4ed6\u4ee5\u540c\u6837\u7684\u5949\u732e\u548c\u5173\u5fc3\u5bf9\u5f85\u6240\u6709\u7684\u75c5\u4eba\u3002\u4ed6\u4e8e1934\u5e741\u67089\u65e5\u6b7b\u4e8e\u4f24\u5bd2\uff0c\u4eab\u5e7452\u5c81\u3002<\/p>\n
\u4e0d\u5e78\u7684\u662f\uff0c\u5f53\u65f6\u7684\u6b27\u6d32\u4eba\u8ba4\u4e3a\u6dcb\u5df4\u7624\u6837\u7532\u72b6\u817a\u80bf\u4e0e\u5f53\u65f6\u6b27\u6d32\u5e38\u89c1\u75c5\u91cc\u5fb7\u5c14\u7532\u72b6\u817a\u708e\uff08Riedel\u2019s thyroiditis\uff09\u6ca1\u6709\u533a\u522b\u3002\u5c3d\u7ba1Simmonds(1913)\u548cHeineke(1914)\u7b49\u53d1\u8868\u4e86\u4e0e\u6865\u672c\u63cf\u8ff0\u76f8\u4f3c\u7684\u75c5\u4f8b\u62a5\u544a\uff0c\u4f46\u5fb7\u56fd\u5b66\u6d3e\u8ba4\u4e3a\u6865\u672c\u6dcb\u5df4\u7624\u662f\u91cc\u5fb7\u5c14\u7532\u72b6\u817a\u708e\u7684\u65e9\u671f\u9636\u6bb5\u3002\u76f4\u52301931\u5e74\uff0cAllen Graham\u7b49\u4eba\u62a5\u9053\u4e86\u6865\u672c\u6dcb\u5df4\u7624\u7684\u8be6\u7ec6\u63cf\u8ff0\uff0c\u5e76\u8d5e\u540c\u6865\u672c\u7684\u7ed3\u8bba\uff0c\u5373\u5b83\u672c\u8eab\u5c31\u662f\u4e00\u79cd\u75be\u75c5\u3002\u81f3\u6b64\uff0c\u8be5\u75c5\u88ab\u547d\u540d\u4e3a\u6865\u672c\u6c0f\u7532\u72b6\u817a\u708e\uff08Hashimoto\u2019s thyroiditis\uff0cHT\uff09\u3002<\/p>\n
70\u5e74\u4ee5\u524d\uff0c\u8bfa\u57c3\u5c14\u00b7\u7f57\u65af(Noel Rose)\u52a0\u5165\u5e03\u6cd5\u7f57\u5927\u5b66\u533b\u5b66\u9662\u6b27\u5185\u65af\u7279\u00b7\u7ef4\u7279\u5e03\u65af\u57fa(Ernest Witebsky)\u5b9e\u9a8c\u5ba4\u3002\u5de5\u4f5c\u662f\u5236\u5907\u7eaf\u7532\u72b6\u817a\u7403\u86cb\u767d\u3002\u7f57\u65af\u5c06\u5404\u79cd\u4e0d\u540c\u53d8\u6027\u7a0b\u5ea6\u7684\u5154\u5b50\u7532\u72b6\u817a\u63d0\u53d6\u7269\u6ce8\u5c04\u5230\u5154\u5b50\u4f53\u5185\u89c2\u5bdf\u662f\u5426\u4f1a\u5f15\u8d77\u514d\u75ab\u53cd\u5e94\u3002\u5f53\u65f6\u6d41\u884c\u7684\u6559\u6761\u8ba4\u4e3a\uff0c\u7531\u4e8e\u201c\u6050\u6016\u81ea\u4f53\u6bd2\u6027\uff08horror autotoxicus\uff09\u201d\u7684\u76ee\u7684\u8bba\u73b0\u8c61\uff08teleological phenomenon\uff09\uff0c\u8eab\u4f53\u65e0\u6cd5\u8bc6\u522b\u81ea\u6211\u86cb\u767d\u8d28\uff0c\u56e0\u6b64\u4efb\u4f55\u514d\u75ab\u53cd\u5e94\u90fd\u610f\u5473\u7740\u86cb\u767d\u8d28\u88ab\u964d\u89e3\uff0c\u4e0d\u518d\u662f\u201c\u81ea\u6211self\u201d\u3002\u201c\u867d\u7136\u9759\u8109\u6ce8\u5c04\u540e\u786e\u5b9e\u6ca1\u6709\u53cd\u5e94\uff0c\u4f46\u968f\u540e\u7684\u5b9e\u9a8c\u4f7f\u7528\u4f50\u5242\u6ce8\u5c04\u5230\u5154\u5b50\u7684\u811a\u57ab\uff08animal\u2019s footpad\uff09\u523a\u6fc0\u514d\u75ab\u7cfb\u7edf\uff0c\u5bfc\u81f4\u610f\u60f3\u4e0d\u5230\u7684\u7532\u72b6\u817a\u7403\u86cb\u767d\u6297\u4f53\u7684\u5f62\u6210\u3002\u4ed6\u7684\u4e0a\u53f8\u8d77\u521d\u5bf9\u8fd9\u4e2a\u53d1\u73b0\u8868\u793a\u6000\u7591\uff0c\u5e76\u8ba9\u7f57\u65af\u91cd\u590d\u4e86\u5f88\u591a\u6b21\u3002\u6700\u7ec8\uff0c1956\u5e74\uff0c\u7f57\u65af\u7eaf\u5316\u4e86\u7532\u72b6\u817a\u7403\u86cb\u767d\u3002\u5c06\u5176\u6ce8\u5c04\u56de\u540c\u4e00\u53ea\u52a8\u7269\u4f53\u5185\uff0c\u4e0d\u4ec5\u53d1\u73b0\u4e86\u6297\u4f53\uff0c\u8fd8\u53d1\u73b0\u4e86\u7532\u72b6\u817a\u708e\u75c7:\u7532\u72b6\u817a\u7ec4\u7ec7\u5b66\u6539\u53d8\u4e0eHT\u76f8\u4f3c\u3002<\/p>\n
\u8fd9\u4e00\u5f00\u521b\u6027\u7684\u53d1\u73b0\u4fc3\u4f7f\u4f26\u6566\u7c73\u5fb7\u5c14\u585e\u514b\u65af(Middlesex)\u533b\u9662\u7684Doniach\u548cRoitt\u9996\u6b21\u5728\u6865\u672c\u7532\u72b6\u817a\u708e\u60a3\u8005\u7684\u8840\u6e05\u4e2d\u68c0\u6d4b\u5230\u7532\u72b6\u817a\u7403\u86cb\u767d\u6297\u4f53\uff0c\u5e76\u65ad\u8a00HT\u60a3\u8005\u5bf9\u4eba\u7532\u72b6\u817a\u7403\u86cb\u767d\u6709\u514d\u75ab\u53cd\u5e94\u3002\u63d0\u51fa\u6865\u672c\u6dcb\u5df4\u7624\u662f\u4e00\u79cd\u7532\u72b6\u817a\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u3002\u8fd9\u4e9b\u53d1\u73b0\u786e\u7acb\u4e86\u5668\u5b98\u7279\u5f02\u6027\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u7684\u6982\u5ff5\uff0cHT\u88ab\u8ba4\u4e3a\u662f\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u30021962\u5e74Doniach\u5728\u300a\u67f3\u53f6\u5200\u300b\u4e0a\u53d1\u8868\u7684\u201c\u81f4\u7f16\u8f91\u7684\u4fe1\u201d\u4e2d\u6709\u4e00\u5f20\u6865\u672c\u7b56\u7684\u8096\u50cf\uff0c\u8fd9\u5f20\u7167\u7247\u662f1912\u5e74\u5728\u54e5\u5ef7\u6839\u62cd\u6444\u7684\u3002\u4ece\u90a3\u4e00\u523b\u8d77\uff0c\u6865\u672c\u7b56\u7684\u5f62\u8c61\u548c\u6210\u5c31\u4e3a\u5168\u4e16\u754c\u6240\u719f\u77e5\uff0c\u6865\u672c\u75c5\u548cHT\u8fd9\u4e24\u4e2a\u672f\u8bed\u4e5f\u8d8a\u6765\u8d8a\u591a\u5730\u51fa\u73b0\u5728\u6559\u79d1\u4e66\u4e2d\u3002<\/p>\n
\u81ea\u53d1\u73b0\u6865\u672c\u6c0f\u75c5\u662f\u4e00\u79cd\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u4ee5\u6765\uff0c\u5728\u8bb8\u591a\u5176\u4ed6\u75be\u75c5\u4e2d\u4e5f\u53d1\u73b0\u4e86\u81ea\u8eab\u514d\u75ab\u6027\u5f02\u5e38\uff0c\u5e76\u88ab\u8ba4\u5b9a\u4e3a\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u3002<\/p>\n
\u3010\u6865\u672c\u6c0f\u7532\u72b6\u817a\u708e\u4e34\u5e8a\u8868\u73b0\u3011<\/p>\n
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\u5173\u6ce8\u516c\u4f17\u53f7\uff0c\u83b7\u53d6\u66f4\u591a\u6587\u7ae0 <\/p>\n
\u53c2\u8003\u6587\u732e<\/p>\n
HashimotoK. My father and his teachers. Endocr J. 2002 Aug;49(4):389-91. doi:10.1507\/endocrj.49.389. PMID: 12402968.<\/p>\n
Hiromatsu,Y., Satoh, H. & Amino, N. Hashimoto\u2019s Thyroiditis: History and Future Outlook.Hormones 12,12\u201318 (2013). https:\/\/\/10.1007\/BF03401282<\/p>\n
Mincer DL, Jialal I. Hashimoto Thyroiditis. 2023 Jul 29.In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023Jan\u2013. PMID: 29083758.<\/p>\n
Tabassom A, Chippa V, Edens MA. De Quervain Thyroiditis. [Updated 2023 Jul 17]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-.Available from: https:\/\/www.ncbi.nlm.\/books\/NBK526066\/<\/p>\n","protected":false},"excerpt":{"rendered":"
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