{"id":53855,"date":"2025-07-01T05:10:14","date_gmt":"2025-07-01T05:10:14","guid":{"rendered":"http:\/\/zydq.1006ss.com\/?p=53855"},"modified":"2025-07-01T05:10:14","modified_gmt":"2025-07-01T05:10:14","slug":"%e5%89%a7%e7%83%88%e5%8d%95%e4%be%a7%e5%a4%b4%e7%97%9b%ef%bc%8c%e4%bc%b4%e5%8f%91%e6%b5%81%e6%b3%aa%e9%bc%bb%e5%a1%9e%ef%bc%9a%e4%b8%89%e5%8f%89%e7%a5%9e%e7%bb%8f%e8%87%aa%e4%b8%bb%e7%9b%b8%e5%85%b3","status":"publish","type":"post","link":"http:\/\/zydq.1006ss.com\/?p=53855","title":{"rendered":"\u5267\u70c8\u5355\u4fa7\u5934\u75db\uff0c\u4f34\u53d1\u6d41\u6cea\u9f3b\u585e\uff1a\u4e09\u53c9\u795e\u7ecf\u81ea\u4e3b\u76f8\u5173\u6027\u5934\u75db\u7684\u8bca\u65ad\u3001\u6cbb\u7597\u53ca\u6700\u65b0\u8fdb\u5c55"},"content":{"rendered":"<h2 align=\"center\" data-pm-slice=\"0 0 []\"><b><\/b><\/h2>\n<p>\u4e09\u53c9\u795e\u7ecf\u81ea\u4e3b\u76f8\u5173\u6027\u5934\u75db\uff08TACs\uff09\u662f\u4e00\u7ec4\u7f55\u89c1\u7684\u539f\u53d1\u6027\u5934\u75db\u75be\u75c5\uff0c\u5176\u7279\u5f81\u662f\u5267\u70c8\u7684\u5355\u4fa7\u5934\u75db\uff0c\u4f34\u968f\u9885\u81ea\u4e3b\u795e\u7ecf\u75c7\u72b6\uff0c\u5982\u6d41\u6cea\u3001\u7ed3\u819c\u5145\u8840\u3001\u9f3b\u585e\u7b49\u3002<\/p>\n<p>TACs\u5305\u62ec\u4e1b\u96c6\u6027\u5934\u75db\u3001\u9635\u53d1\u6027\u504f\u4fa7\u5934\u75db\u3001\u6301\u7eed\u6027\u504f\u4fa7\u5934\u75db\u3001SUNCT\uff08\u4f34\u7ed3\u819c\u5145\u8840\u548c\u6d41\u6cea\u7684\u77ed\u6682\u5355\u4fa7\u795e\u7ecf\u75db\u6837\u5934\u75db\u53d1\u4f5c\uff09\u548cSUNA\uff08\u4f34\u9885\u81ea\u4e3b\u795e\u7ecf\u75c7\u72b6\u7684\u77ed\u6682\u5355\u4fa7\u795e\u7ecf\u75db\u6837\u5934\u75db\u53d1\u4f5c\uff09\u3002<\/p>\n<p>\u7531\u4e8e\u8fd9\u4e9b\u75be\u75c5\u7684\u7f55\u89c1\u6027\u548c\u590d\u6742\u6027\uff0c\u6cbb\u7597\u548c\u7ba1\u7406\u4e00\u76f4\u662f\u4e00\u4e2a\u6311\u6218\u3002\u672c\u6587\u5c06\u4e3a\u60a8\u8be6\u7ec6\u89e3\u8bfbTACs\u7684\u8bca\u65ad\u3001\u6cbb\u7597\u53ca\u6700\u65b0\u7814\u7a76\u8fdb\u5c55\u3002<\/p>\n<p>01\u4ec0\u4e48\u662fTACsTACs\u662f\u4e00\u7ec4\u4ee5\u5355\u4fa7\u5934\u75db\u548c\u9885\u81ea\u4e3b\u795e\u7ecf\u75c7\u72b6\u4e3a\u7279\u5f81\u7684\u5934\u75db\u75be\u75c5\u3002\u6700\u5e38\u89c1\u7684\u7c7b\u578b\u662f\u4e1b\u96c6\u6027\u5934\u75db\uff0c\u60a3\u8005\u901a\u5e38\u63cf\u8ff0\u5934\u75db\u4e3a\u201c\u5200\u5272\u6837\u201d\u6216\u201c\u94bb\u75db\u201d\uff0c\u4e14\u75bc\u75db\u96c6\u4e2d\u5728\u773c\u7736\u5468\u56f4\u3002&nbsp;&nbsp;\u5176\u4ed6\u7c7b\u578b\u7684TACs\u5305\u62ec\u9635\u53d1\u6027\u504f\u4fa7\u5934\u75db\u3001\u6301\u7eed\u6027\u504f\u4fa7\u5934\u75db\u3001SUNCT\u548cSUNA\u3002\u8fd9\u4e9b\u5934\u75db\u7684\u5171\u540c\u7279\u70b9\u662f\u53d1\u4f5c\u65f6\u95f4\u77ed\u3001\u75bc\u75db\u5267\u70c8\uff0c\u4e14\u4f34\u968f\u81ea\u4e3b\u795e\u7ecf\u75c7\u72b6\u3002TACs \u662f\u4e25\u683c\u5355\u4fa7\u7684\u5934\u75db\u3002\u5927\u591a\u6570 TACs \u53ef\u4ee5\u8868\u73b0\u4e3a\u53d1\u4f5c\u6027\u6216\u6162\u6027\u5f62\u5f0f\u3002\u533a\u5206\u8fd9\u4e9b\u75be\u75c5\u7684\u6700\u91cd\u8981\u7279\u5f81\u662f\u5934\u75db\u53d1\u4f5c\u7684\u6301\u7eed\u65f6\u95f4\u300202\u4e1b\u96c6\u6027\u5934\u75db\uff1a\u6700\u5178\u578b\u7684TACs<\/p>\n<p>\u4e1b\u96c6\u6027\u5934\u75db\u662fTACs\u4e2d\u6700\u5e38\u89c1\u7684\u4e00\u79cd\uff0c\u5206\u4e3a\u53d1\u4f5c\u6027\u4e1b\u96c6\u6027\u5934\u75db\u548c\u6162\u6027\u4e1b\u96c6\u6027\u5934\u75db\u3002\u53d1\u4f5c\u6027\u4e1b\u96c6\u6027\u5934\u75db\u7684\u7279\u70b9\u662f\u5934\u75db\u53d1\u4f5c\u671f\u6301\u7eed\u6570\u5468\u81f3\u6570\u6708\uff0c\u968f\u540e\u6709\u7f13\u89e3\u671f\uff1b\u800c\u6162\u6027\u4e1b\u96c6\u6027\u5934\u75db\u7684\u53d1\u4f5c\u5219\u6301\u7eed\u8d85\u8fc7\u4e00\u5e74\uff0c\u7f13\u89e3\u671f\u5c11\u4e8e\u4e00\u4e2a\u6708\u3002<\/p>\n<p>\u4e1b\u96c6\u6027\u5934\u75db\u7684\u5178\u578b\u75c7\u72b6\uff1a<b><\/b><\/p>\n<ul>\n<li>\n<p>\u5267\u70c8\u7684\u5355\u4fa7\u5934\u75db\uff0c\u901a\u5e38\u96c6\u4e2d\u5728\u773c\u7736\u5468\u56f4\u3002<\/p>\n<\/li>\n<\/ul>\n<ul>\n<li>\n<p>\u4f34\u968f\u81ea\u4e3b\u795e\u7ecf\u75c7\u72b6\uff0c\u5982\u6d41\u6cea\u3001\u7ed3\u819c\u5145\u8840\u3001\u9f3b\u585e\u7b49\u3002<\/p>\n<\/li>\n<\/ul>\n<ul>\n<li>\n<p>\u5934\u75db\u53d1\u4f5c\u901a\u5e38\u6301\u7eed15\u5206\u949f\u81f33\u5c0f\u65f6\uff0c\u53d1\u4f5c\u9891\u7387\u4e3a\u6bcf\u59291-8\u6b21\u3002<\/p>\n<\/li>\n<\/ul>\n<p>03TACs\u7684\u6cbb\u7597\uff1a\u6025\u6027\u53d1\u4f5c\u4e0e\u9884\u9632<\/p>\n<p>TACs\u7684\u6cbb\u7597\u5206\u4e3a\u6025\u6027\u53d1\u4f5c\u6cbb\u7597\u548c\u9884\u9632\u6cbb\u7597\u3002\u6025\u6027\u53d1\u4f5c\u6cbb\u7597\u7684\u76ee\u7684\u662f\u5feb\u901f\u7f13\u89e3\u75bc\u75db\uff0c\u800c\u9884\u9632\u6cbb\u7597\u5219\u662f\u51cf\u5c11\u6216\u963b\u6b62\u5934\u75db\u7684\u590d\u53d1\u3002<\/p>\n<p>PART&nbsp;01\u6025\u6027\u53d1\u4f5c\u6cbb\u7597<b><\/b><\/p>\n<ul>\n<li>\n<p>\u6c27\u6c14\u5438\u5165\uff1a100%\u6c27\u6c14\u901a\u8fc7\u9762\u7f69\u5438\u5165\uff0c\u662f\u4e1b\u96c6\u6027\u5934\u75db\u6025\u6027\u53d1\u4f5c\u7684\u9996\u9009\u6cbb\u7597\u65b9\u6cd5\uff0c\u6709\u6548\u4e14\u65e0\u526f\u4f5c\u7528\u3002<\/p>\n<\/li>\n<\/ul>\n<ul>\n<li>\n<p>\u8212\u9a6c\u666e\u5766\uff08Sumatriptan\uff09\uff1a\u76ae\u4e0b\u6ce8\u5c04\u6216\u9f3b\u55b7\u5242\uff0c\u80fd\u591f\u5feb\u901f\u7f13\u89e3\u75bc\u75db\uff0c\u4f46\u9700\u6ce8\u610f\u5fc3\u8840\u7ba1\u75be\u75c5\u60a3\u8005\u7684\u7981\u5fcc\u75c7\u3002<\/p>\n<\/li>\n<\/ul>\n<ul>\n<li>\n<p>\u975e\u4fb5\u5165\u6027\u8ff7\u8d70\u795e\u7ecf\u523a\u6fc0\uff08nVNS\uff09\uff1a\u901a\u8fc7\u9888\u90e8\u7684\u7ecf\u76ae\u523a\u6fc0\uff0c\u51cf\u5c11\u53d1\u4f5c\u9891\u7387\u3002<\/p>\n<\/li>\n<\/ul>\n<p>PART&nbsp;02\u9884\u9632\u6cbb\u7597<\/p>\n<ul>\n<li>\n<p>\u7ef4\u62c9\u5e15\u7c73\uff08Verapamil\uff09\uff1a\u662f\u4e1b\u96c6\u6027\u5934\u75db\u7684\u4e00\u7ebf\u9884\u9632\u836f\u7269\uff0c\u5242\u91cf\u9010\u6e10\u589e\u52a0\u81f3200-480 mg\/\u5929\u3002<\/p>\n<\/li>\n<\/ul>\n<ul>\n<li>\n<p>\u9502\u76d0\uff08Lithium\uff09\uff1a\u9002\u7528\u4e8e\u6162\u6027\u4e1b\u96c6\u6027\u5934\u75db\uff0c\u4f46\u9700\u5b9a\u671f\u76d1\u6d4b\u8840\u836f\u6d53\u5ea6\uff0c\u4ee5\u907f\u514d\u6bd2\u6027\u53cd\u5e94\u3002<\/p>\n<\/li>\n<\/ul>\n<ul>\n<li>\n<p>\u6258\u5421\u916f\uff08Topiramate\uff09\uff1a\u7528\u4e8e\u96be\u6cbb\u6027\u75c5\u4f8b\uff0c\u5242\u91cf100-200 mg\/\u5929\u3002<\/p>\n<\/li>\n<\/ul>\n<ul>\n<li>\n<p>Galcanezumab\uff1a\u4e00\u79cd\u9488\u5bf9CGRP\uff08\u964d\u9499\u7d20\u57fa\u56e0\u76f8\u5173\u80bd\uff09\u7684\u5355\u514b\u9686\u6297\u4f53\uff0c\u5df2\u88abFDA\u6279\u51c6\u7528\u4e8e\u53d1\u4f5c\u6027\u4e1b\u96c6\u6027\u5934\u75db\u7684\u9884\u9632\uff0c\u4f46\u5bf9\u6162\u6027\u4e1b\u96c6\u6027\u5934\u75db\u7684\u6548\u679c\u6709\u9650\u3002<\/p>\n<\/li>\n<\/ul>\n<p>04\u795e\u7ecf\u8c03\u63a7\u6cbb\u7597\uff1a\u836f\u7269\u65e0\u6548\u65f6\u7684\u9009\u62e9<\/p>\n<p>\u5bf9\u4e8e\u836f\u7269\u7597\u6548\u4e0d\u4f73\u6216\u65e0\u6cd5\u8010\u53d7\u7684\u60a3\u8005\uff0c\u795e\u7ecf\u8c03\u63a7\u6cbb\u7597\u63d0\u4f9b\u4e86\u4e00\u79cd\u65b0\u7684\u9009\u62e9\u3002\u5e38\u89c1\u7684\u795e\u7ecf\u8c03\u63a7\u65b9\u6cd5\u5305\u62ec\uff1a<\/p>\n<ul>\n<li>\n<p>\u6795\u795e\u7ecf\u523a\u6fc0\uff08ONS\uff09\uff1a\u901a\u8fc7\u690d\u5165\u7535\u6781\u523a\u6fc0\u6795\u795e\u7ecf\uff0c\u51cf\u5c11\u53d1\u4f5c\u9891\u7387\u3002<\/p>\n<\/li>\n<\/ul>\n<ul>\n<li>\n<p>\u8776\u816d\u795e\u7ecf\u8282\u523a\u6fc0\uff08SPG\uff09\uff1a\u901a\u8fc7\u690d\u5165\u7535\u6781\u523a\u6fc0\u8776\u816d\u795e\u7ecf\u8282\uff0c\u51cf\u5c11\u53d1\u4f5c\u9891\u7387\u3002<\/p>\n<\/li>\n<\/ul>\n<ul>\n<li>\n<p>\u8ff7\u8d70\u795e\u7ecf\u523a\u6fc0\uff08VNS\uff09\uff1a\u975e\u4fb5\u5165\u6027\u8ff7\u8d70\u795e\u7ecf\u523a\u6fc0\uff0c\u7528\u4e8e\u6025\u6027\u548c\u9884\u9632\u6027\u6cbb\u7597\u3002<\/p>\n<\/li>\n<\/ul>\n<p>\u8fd9\u4e9b\u6cbb\u7597\u65b9\u6cd5\u867d\u7136\u6709\u6548\uff0c\u4f46\u7531\u4e8e\u5176\u4fb5\u5165\u6027\uff0c\u901a\u5e38\u4ec5\u7528\u4e8e\u836f\u7269\u96be\u6cbb\u6027\u60a3\u8005\u3002<\/p>\n<p>05\u9635\u53d1\u6027\u504f\u4fa7\u5934\u75db\u548c\u6301\u7eed\u6027\u504f\u4fa7\u5934\u75db\u7684\u6cbb\u7597<\/p>\n<p>\u9635\u53d1\u6027\u504f\u4fa7\u5934\u75db\u548c\u6301\u7eed\u6027\u504f\u4fa7\u5934\u75db\u662fTACs\u7684\u53e6\u5916\u4e24\u79cd\u7c7b\u578b\uff0c\u5b83\u4eec\u7684\u5171\u540c\u7279\u70b9\u662f\u5bf9\u5432\u54da\u7f8e\u8f9b\uff08Indomethacin\uff09\u5b8c\u5168\u6709\u6548\u3002\u5432\u54da\u7f8e\u8f9b\u662f\u4e00\u79cd\u975e\u753e\u4f53\u6297\u708e\u836f\uff0c\u901a\u5e38\u5242\u91cf\u4e3a25-150 mg\/\u5929\uff0c\u9010\u6e10\u589e\u52a0\u5242\u91cf\u3002\u5bf9\u4e8e\u65e0\u6cd5\u8010\u53d7\u5432\u54da\u7f8e\u8f9b\u7684\u60a3\u8005\uff0c\u6258\u5421\u916f\u3001\u7ef4\u62c9\u5e15\u7c73\u3001\u5361\u9a6c\u897f\u5e73\u7b49\u836f\u7269\u53ef\u4ee5\u4f5c\u4e3a\u66ff\u4ee3\u6cbb\u7597\u3002<\/p>\n<p>06SUNCT\u548cSUNA\uff1a\u77ed\u6682\u4f46\u5267\u70c8\u7684\u5934\u75db<\/p>\n<p>SUNCT\u548cSUNA\u662fTACs\u4e2d\u6700\u7f55\u89c1\u7684\u7c7b\u578b\uff0c\u5176\u7279\u5f81\u662f\u77ed\u6682\u4f46\u5267\u70c8\u7684\u5355\u4fa7\u5934\u75db\u53d1\u4f5c\uff0c\u4f34\u968f\u7ed3\u819c\u5145\u8840\u3001\u6d41\u6cea\u7b49\u81ea\u4e3b\u795e\u7ecf\u75c7\u72b6\u3002\u8fd9\u4e9b\u5934\u75db\u7684\u53d1\u4f5c\u9891\u7387\u6781\u9ad8\uff0c\u6bcf\u5929\u53ef\u8fbe1-100\u6b21\u3002<\/p>\n<p><b>\u6cbb\u7597\u65b9\u6cd5\uff1a<\/b><b><\/b><\/p>\n<ul>\n<li>\n<p>\u62c9\u83ab\u4e09\u55ea\uff08Lamotrigine\uff09\uff1a\u662fSUNCT\u548cSUNA\u7684\u4e00\u7ebf\u9884\u9632\u836f\u7269\uff0c\u5242\u91cf50-700 mg\/\u5929\u3002<\/p>\n<\/li>\n<\/ul>\n<ul>\n<li>\n<p>\u6258\u5421\u916f\uff08Topiramate\uff09\uff1a\u7528\u4e8e\u90e8\u5206\u60a3\u8005\u7684\u8f85\u52a9\u6cbb\u7597\u3002<\/p>\n<\/li>\n<\/ul>\n<ul>\n<li>\n<p>\u795e\u7ecf\u8c03\u63a7\uff1a\u6795\u795e\u7ecf\u523a\u6fc0\u3001\u8776\u816d\u795e\u7ecf\u8282\u5c04\u9891\u6d88\u878d\u7b49\u3002<\/p>\n<\/li>\n<\/ul>\n<ul>\n<li>\n<p>\u624b\u672f\u6cbb\u7597\uff1a\u4e09\u53c9\u795e\u7ecf\u5fae\u8840\u7ba1\u51cf\u538b\u672f\uff0c\u9002\u7528\u4e8e\u96be\u6cbb\u6027\u75c5\u4f8b\u3002<\/p>\n<\/li>\n<\/ul>\n<p>07\u672a\u6765\u7814\u7a76\u65b9\u5411<\/p>\n<p>\u5c3d\u7ba1TACs\u7684\u6cbb\u7597\u5df2\u7ecf\u53d6\u5f97\u4e86\u4e00\u4e9b\u8fdb\u5c55\uff0c\u4f46\u7531\u4e8e\u5176\u7f55\u89c1\u6027\u548c\u590d\u6742\u6027\uff0c\u4ecd\u7136\u5b58\u5728\u8bb8\u591a\u6311\u6218\u3002\u672a\u6765\u7684\u7814\u7a76\u65b9\u5411\u5305\u62ec\uff1a<\/p>\n<ul>\n<li>\n<p>\u591a\u4e2d\u5fc3\u5408\u4f5c\u7814\u7a76\uff1a\u901a\u8fc7\u5efa\u7acb\u6807\u51c6\u5316\u60a3\u8005\u767b\u8bb0\u7cfb\u7edf\uff0c\u63a8\u52a8TACs\u6cbb\u7597\u7684\u8fdb\u4e00\u6b65\u8fdb\u5c55\u3002<\/p>\n<\/li>\n<\/ul>\n<ul>\n<li>\n<p>\u63a2\u7d22\u65b0\u7684\u751f\u7269\u6807\u5fd7\u7269\u548c\u6cbb\u7597\u9776\u70b9\uff1a\u4f18\u5316\u4e34\u5e8a\u8bd5\u9a8c\u8bbe\u8ba1\uff0c\u5bfb\u627e\u66f4\u6709\u6548\u7684\u6cbb\u7597\u65b9\u6cd5\u3002<\/p>\n<\/li>\n<\/ul>\n<p>\u53c2\u8003\u6587\u732e\uff1aDiener HC, Tassorelli C, Dodick DW. Management of Trigeminal Autonomic Cephalalgias Including Chronic Cluster: A Review. 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