{"id":53763,"date":"2025-06-29T05:10:04","date_gmt":"2025-06-29T05:10:04","guid":{"rendered":"http:\/\/zydq.1006ss.com\/?p=53763"},"modified":"2025-06-29T05:10:04","modified_gmt":"2025-06-29T05:10:04","slug":"%e3%80%90%e7%bb%bc%e8%bf%b0%e3%80%91%e9%a2%85%e5%86%85%e5%87%ba%e8%a1%80%e5%90%8e%e9%87%8d%e5%90%af%e6%8a%97%e8%a1%80%e6%a0%93%e6%b2%bb%e7%96%97%e7%9a%84%e7%a0%94%e7%a9%b6%e8%bf%9b%e5%b1%95","status":"publish","type":"post","link":"http:\/\/zydq.1006ss.com\/?p=53763","title":{"rendered":"\u3010\u7efc\u8ff0\u3011\u9885\u5185\u51fa\u8840\u540e\u91cd\u542f\u6297\u8840\u6813\u6cbb\u7597\u7684\u7814\u7a76\u8fdb\u5c55"},"content":{"rendered":"

\u6587\u7ae0\u6765\u6e90\uff1a\u4e2d\u534e\u795e\u7ecf\u79d1\u6742\u5fd7, 2023,56(2) : 204-211<\/p>\n

\u4f5c\u8005\uff1a\u674e\u80dc\u5fb7 \u502a\u4fca \u5f6d\u658c<\/p>\n

\u6458\u8981<\/p>\n

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\u5728\u4e34\u5e8a\u5de5\u4f5c\u4e2d\uff0c\u4e34\u5e8a\u533b\u5e08\u5e38\u9047\u5230\u5177\u6709\u6297\u8840\u6813\u6cbb\u7597\u6307\u5f81\u7684\u9885\u5185\u51fa\u8840\u60a3\u8005\uff0c\u4f8b\u5982\u4f34\u6709\u5fc3\u623f\u98a4\u52a8\u7684\u8111\u51fa\u8840\u60a3\u8005\uff0c\u5176\u518d\u53d1\u8840\u6813\u6813\u585e\u4e8b\u4ef6\u7684\u98ce\u9669\u4ea6\u589e\u9ad8\uff3b<\/sup>8\uff3d<\/sup>\u3002\u4f46\u9885\u5185\u51fa\u8840\u540e\u662f\u5426\u542f\u52a8\u6297\u8840\u6813\u6cbb\u7597\uff0c\u4f55\u65f6\u542f\u52a8\u6cbb\u7597\u4ee5\u53ca\u6cbb\u7597\u65b9\u6848\u5982\u4f55\u786e\u5b9a\uff0c\u56fd\u5185\u53ca\u56fd\u9645\u6307\u5357\u5747\u7f3a\u4e4f\u9ad8\u8d28\u91cf\u7684\u63a8\u8350\u610f\u89c1\u3002\u6b64\u5916\uff0c\u5728\u5352\u4e2d\u6297\u8840\u6813\u6cbb\u7597\u7684\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\uff0c\u6b64\u7c7b\u60a3\u8005\u591a\u88ab\u6392\u9664\u5728\u5916\uff3b<\/sup>3\uff0c9, 10, 11, 12\uff3d<\/sup>\u3002\u56e0\u6b64\uff0c\u6b64\u7c7b\u60a3\u8005\u7684\u6cbb\u7597\u5e38\u9677\u5165\u4e24\u96be\u56f0\u5883\uff0c\u4e34\u5e8a\u533b\u5e08\u51b3\u7b56\u7f3a\u4e4f\u4f9d\u636e\u3002\u800c\u771f\u5b9e\u4e16\u754c\u4e2d\u91cd\u542f\u6297\u8840\u6813\u6cbb\u7597\u7684\u6bd4\u4f8b\u6ce2\u52a8\u4e8e11%~45%\uff0c\u4e0d\u540c\u4e2d\u5fc3\u7684\u6cbb\u7597\u7b56\u7565\u5dee\u5f02\u660e\u663e\uff3b<\/sup>13, 14\uff3d<\/sup>\u3002<\/p>\n

\u6211\u4eec\u4ee5\u201cintracranial hemorrhage\u201d\u201cthromboembolism\u201d\u201crecurrence\u201d\u201canticoagulants\u201d\u201cplatelet aggregation inhibitors\u201d\u201crestart\u201d\u53ca\u201cresumption\u201d\u4e3a\u82f1\u6587\u5173\u952e\u8bcd\u5728PubMed\u6570\u636e\u5e93\u4e2d\u68c0\u7d22\u76f8\u5173\u82f1\u6587\u6587\u732e\uff0c\u540c\u65f6\u4ee5\u201c\u9885\u5185\u51fa\u8840\u201d\u201c\u6297\u51dd\u836f\u201d\u201c\u8840\u5c0f\u677f\u805a\u96c6\u6291\u5236\u5242\u201d\u201c\u8840\u6813\u6813\u585e\u201d\u201c\u590d\u53d1\u201d\u53ca\u201c\u91cd\u542f\u201d\u4e3a\u4e2d\u6587\u5173\u952e\u8bcd\u5728\u4e07\u65b9\u6570\u636e\u5e93\u4e2d\u68c0\u7d22\u76f8\u5173\u4e2d\u6587\u6587\u732e\uff0c\u6587\u732e\u68c0\u7d22\u8d77\u6b62\u65f6\u95f4\u4e3a1990\u5e741\u6708\u81f32022\u5e744\u6708\uff0c\u65e8\u5728\u5f52\u7eb3\u603b\u7ed3\u9885\u5185\u51fa\u8840\u540e\u91cd\u542f\u6297\u8840\u6813\u6cbb\u7597\u7684\u5229\u5f0a\u53ca\u73b0\u72b6\uff0c\u4ee5\u63d0\u9ad8\u4e34\u5e8a\u533b\u5e08\u5bf9\u6b64\u7c7b\u60a3\u8005\u7684\u8ba4\u8bc6\uff0c\u4e3a\u5176\u4e34\u5e8a\u51b3\u7b56\u63d0\u4f9b\u53c2\u8003\u3002<\/p>\n

\u4e00\u3001\u91cd\u542f\u6297\u8840\u6813\u6cbb\u7597\u7684\u6311\u6218<\/p>\n

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\u4e8c\u3001\u9885\u5185\u51fa\u8840\u7684\u75c5\u56e0<\/p>\n

\u9885\u5185\u51fa\u8840\u5305\u62ec\u8111\u51fa\u8840\u3001\u86db\u7f51\u819c\u4e0b\u8154\u51fa\u8840\u3001\u786c\u819c\u4e0b\u51fa\u8840\u3001\u786c\u819c\u5916\u51fa\u8840\uff0c\u75c5\u56e0\u591a\u6837\uff0c\u53ef\u5206\u4e3a\u521b\u4f24\u6027\u53ca\u81ea\u53d1\u6027\u9885\u5185\u51fa\u8840\u3002\u81ea\u53d1\u6027\u8111\u51fa\u8840\u7684\u53d1\u75c5\u7387\u7ea6\u4e3a24.6\/10\u4e07\uff0c\u53d1\u75c5\u7387\u968f\u5e74\u9f84\u589e\u957f\uff3b<\/sup>2\uff3d<\/sup>\uff0c\u5176\u75c5\u56e0\u6309SMASH-U\u5206\u578b\u5206\u4e3a\u7ed3\u6784\u6027\u75c5\u53d8\uff084.9%\uff09\u3001\u836f\u7269\uff0814.1%\uff09\u3001\u8111\u6dc0\u7c89\u6837\u8840\u7ba1\u75c5\uff08cerebral amyloid angiopathy\uff0cCAA\uff1b20.2%\uff09\u3001\u7cfb\u7edf\u6027\u75be\u75c5\uff084.7%\uff09\u3001\u9ad8\u8840\u538b\uff0834.9%\uff09\u53ca\u672a\u77e5\u539f\u56e0\uff0821.0%\uff09\uff3b<\/sup>3\uff0c20\uff3d<\/sup>\u3002\u73b0\u5c06\u4e0d\u540c\u75c5\u56e0\u76f8\u5173\u7684\u9885\u5185\u51fa\u8840\u60a3\u8005\u7684\u4e34\u5e8a\u7279\u70b9\u7b80\u8981\u4ecb\u7ecd\u5982\u4e0b\uff0c\u65e8\u5728\u4e3a\u4e34\u5e8a\u533b\u5e08\u91cd\u542f\u6297\u8840\u6813\u6cbb\u7597\u51b3\u7b56\u63d0\u4f9b\u57fa\u7ebf\u8d44\u6599\u3002<\/p>\n

\uff08\u4e00\uff09\u9ad8\u8840\u538b<\/p>\n

\u76ee\u524d\u9ad8\u8840\u538b\u76f8\u5173\u8111\u51fa\u8840\u7684\u53d1\u75c5\u7387\u53ca\u60a3\u75c5\u7387\u5747\u4e0d\u660e\u786e\uff0c\u4f46\u9ad8\u8840\u538b\u76f8\u5173\u8111\u51fa\u8840\u662f\u81ea\u53d1\u6027\u8111\u51fa\u8840\u6700\u5e38\u89c1\u7684\u7c7b\u578b\uff0c\u9ad8\u8840\u538b\u4e5f\u662f\u9885\u5185\u51fa\u8840\u5e38\u89c1\u7684\u5371\u9669\u56e0\u7d20\uff3b<\/sup>3\uff0c10\uff3d<\/sup>\uff0c80%\u7684\u8111\u51fa\u8840\u60a3\u8005\u5408\u5e76\u9ad8\u8840\u538b\uff3b<\/sup>19\uff3d<\/sup>\u3002\u8111\u53f6\u578b\u53ca\u975e\u8111\u53f6\u578b\u8111\u51fa\u8840\u7684\u5371\u9669\u56e0\u7d20\u5747\u5305\u62ec\u9ad8\u8840\u538b\uff3b<\/sup>21\uff3d<\/sup>\u3002<\/p>\n

\uff08\u4e8c\uff09\u836f\u7269<\/p>\n

\u836f\u7269\u76f8\u5173\u9885\u5185\u51fa\u8840\u4e3a\u76ee\u524d\u7814\u7a76\u7684\u70ed\u70b9\u3002\u6297\u51dd\u836f\u7269\u53ca\u6297\u8840\u5c0f\u677f\u836f\u7269\u76f8\u5173\u9885\u5185\u51fa\u8840\u7814\u7a76\u6d89\u53ca\u60a3\u8005\u7684\u5e73\u5747\u5e74\u9f84\u5206\u522b\u4e3a71.5~84.8\u5c81\u53ca59~65\u5c81\u3002\u6297\u51dd\u836f\u7269\u76f8\u5173\u9885\u5185\u51fa\u8840\u7684\u5e74\u53d1\u75c5\u7387\u4e3a0.23%~0.80%\uff3b<\/sup>22, 23, 24, 25\uff3d<\/sup>\uff0c\u8111\u51fa\u8840\u3001\u786c\u819c\u4e0b\u51fa\u8840\u53ca\u86db\u7f51\u819c\u4e0b\u8154\u51fa\u8840\u5360\u6bd4\u5206\u522b\u4e3a46%\u300145%\u53ca8%\uff3b<\/sup>25\uff3d<\/sup>\u3002\u65b0\u578b\u53e3\u670d\u6297\u51dd\u836f\u7269\u76f8\u5173\u7684\u9885\u5185\u51fa\u8840\u7387\uff080.23%~0.35%\uff09\u4f4e\u4e8e\u4e0e\u534e\u6cd5\u6797\u76f8\u5173\u7684\u9885\u5185\u51fa\u8840\u7387\uff080.59%~0.80%\uff09\uff3b<\/sup>22, 23\uff0c25\uff3d<\/sup>\uff1b\u6b64\u5916\uff0c\u65b0\u578b\u53e3\u670d\u6297\u51dd\u836f\u7269\u7684\u9885\u5185\u51fa\u8840\u98ce\u9669\u5448\u5242\u91cf\u4f9d\u8d56\u6027\uff3b<\/sup>25\uff3d<\/sup>\u3002\u4f46\u534e\u6cd5\u6797\u76f8\u5173\u9885\u5185\u51fa\u8840\u5177\u6709\u4e0d\u53ef\u9884\u6d4b\u6027\uff0c\u8fd180%\u7684\u9885\u5185\u51fa\u8840\u53d1\u751f\u4e8e\u56fd\u9645\u6807\u51c6\u5316\u6bd4\u503c\uff08INR\uff09\u5904\u4e8e\u6cbb\u7597\u8303\u56f4\u5185\u65f6\uff3b<\/sup>22\uff3d<\/sup>\u3002\u6b64\u5916\uff0c\u963f\u53f8\u5339\u6797\u76f8\u5173\u8111\u51fa\u88403\u4e2a\u6708\u53ca3\u5e74\u7684\u53d1\u75c5\u7387\u5206\u522b\u4e3a0.1%~0.3%\u53ca0.12%\uff3b<\/sup>12\uff0c26, 27\uff3d<\/sup>\uff1b\u800c\u8054\u7528\u963f\u53f8\u5339\u6797\u53ca\u6c2f\u5421\u683c\u96f7\u540e\u60a3\u80053\u4e2a\u6708\u5185\u7684\u9885\u5185\u51fa\u8840\u7387\u4e3a0.2%~0.3%\uff3b<\/sup>12\uff0c27\uff3d<\/sup>\u3002<\/p>\n

\uff08\u4e09\uff09\u8111\u6897\u6b7b\u540e\u51fa\u8840\u8f6c\u5316<\/p>\n

\u8111\u6897\u6b7b\u540e\u51fa\u8840\u8f6c\u5316\u7387\u5dee\u5f02\u5de8\u5927\uff0c\u4e14\u53d7\u5e72\u9884\u63aa\u65bd\u53ca\u75be\u75c5\u4e25\u91cd\u7a0b\u5ea6\u7684\u5f71\u54cd\uff3b<\/sup>28\uff3d<\/sup>\u3002\u901a\u5e38\u5c06\u5176\u5206\u4e3a\u65e0\u75c7\u72b6\u6027\u51fa\u8840\u8f6c\u5316\u53ca\u75c7\u72b6\u6027\u51fa\u8840\u8f6c\u5316\u3002\u8111\u6897\u6b7b\u9759\u8109\u6eb6\u6813\u540e\u7684\u51fa\u8840\u8f6c\u5316\u7387\u4e3a10%~48%\uff0c\u8840\u7ba1\u5185\u6cbb\u7597\u540e\u7684\u51fa\u8840\u8f6c\u5316\u7387\u4e3a38.9%\uff3b<\/sup>9\uff0c28\uff3d<\/sup>\u3002\u6eb6\u6813\u540e\u75c7\u72b6\u6027\u51fa\u8840\u7684\u8f6c\u5316\u7387\u4e3a2%~7%\uff3b<\/sup>29\uff3d<\/sup>\uff0c\u975e\u74e3\u819c\u6027\u5fc3\u623f\u98a4\u52a8\u76f8\u5173\u8111\u6897\u6b7b\u60a3\u80052\u5468\u5185\u7684\u51fa\u8840\u8f6c\u5316\u7387\u4e3a43.2%\uff3b<\/sup>28\uff3d<\/sup>\u3002\u4e2d\u56fd\u4eba\u7fa4\u65e0\u75c7\u72b6\u53ca\u75c7\u72b6\u6027\u51fa\u8840\u8f6c\u5316\u7684\u6bd4\u7387\u4e3a2\u22361\uff0c62%\u7684\u51fa\u8840\u8f6c\u5316\u4e8b\u4ef6\u53d1\u751f\u4e8e\u8111\u6897\u6b7b\u8d77\u75c5\u540e1\u5468\u5185\uff3b<\/sup>30\uff3d<\/sup>\u3002<\/p>\n

\uff08\u56db\uff09CAA<\/p>\n

CAA\u662f\u81ea\u53d1\u6027\u8111\u51fa\u8840\u7684\u91cd\u8981\u75c5\u56e0\uff0c\u7ea6\u5360\u51761\/5\uff0cCAA\u76f8\u5173\u8111\u51fa\u8840\u7684\u5e74\u53d1\u75c5\u7387\u4e3a7%~12%\uff0c\u4ee5\u8111\u53f6\u51fa\u8840\u53ca\u8111\u53f6\u5fae\u51fa\u8840\u4e3a\u4e3b\uff3b<\/sup>31\uff3d<\/sup>\uff0c\u51fa\u8840\u98ce\u9669\u4e0e\u8111\u5fae\u51fa\u8840\u7076\u6570\u76ee\u5448\u6b63\u76f8\u5173\uff3b<\/sup>32\uff3d<\/sup>\u3002\u5728\u968f\u8bbf3\u5e74\u7684CAA\u60a3\u8005\u4e2d\uff0c\u76ae\u8d28\u8868\u9762\u94c1\u6c89\u79ef\u60a3\u8005\u7684\u8111\u51fa\u8840\u7387\u4e3a19%\uff0c\u800c\u65e0\u76ae\u8d28\u8868\u9762\u94c1\u6c89\u79ef\u7684\u60a3\u8005\u8111\u51fa\u8840\u7387\u4ec5\u4e3a6%\uff3b<\/sup>33\uff3d<\/sup>\u3002<\/p>\n

\uff08\u4e94\uff09\u521b\u4f24\u6027\u8111\u51fa\u8840<\/p>\n

\u6211\u56fd\u76ee\u524d\u7f3a\u4e4f\u521b\u4f24\u6027\u8111\u51fa\u8840\u7684\u76f8\u5173\u6570\u636e\uff0c\u7f8e\u56fd\u5168\u5e74\u521b\u4f24\u6027\u8111\u635f\u4f24\u60a3\u8005\u7ea6280\u4e07\u4f8b\uff0c\u5176\u4e2d80%\u4e3a\u8f7b\u75c7\uff3b<\/sup>34, 35\uff3d<\/sup>\uff0c\u5176\u8868\u73b0\u4e4b\u4e00\u4e3a\u521b\u4f24\u6027\u8111\u51fa\u8840\u3002\u5728\u521b\u4f24\u6027\u8111\u51fa\u8840\u60a3\u8005\u4e2d\uff0c\u7ecf\u795e\u7ecf\u5916\u79d1\u624b\u672f\u5e72\u9884\u7684\u6bd4\u4f8b\u7ea6\u4e3a6.7%\uff3b<\/sup>36\uff3d<\/sup>\u3002\u5408\u7528\u6297\u8840\u6813\u836f\u7269\u5e76\u672a\u589e\u52a0\u521b\u4f24\u6027\u9885\u5185\u51fa\u8840\u7684\u53d1\u751f\u7387\u53ca\u4e25\u91cd\u7a0b\u5ea6\uff3b<\/sup>37\uff3d<\/sup>\u3002\u521b\u4f24\u6027\u9885\u5185\u51fa\u8840\u60a3\u8005\u4ecd\u9700\u6392\u67e5\u5176\u4ed6\u975e\u521b\u4f24\u6027\u7684\u5371\u9669\u56e0\u7d20\u3002<\/p>\n

\u4e09\u3001\u9885\u5185\u51fa\u8840\u540e\u8840\u6813\u6813\u585e\u53ca\u51fa\u8840\u590d\u53d1\u7684\u98ce\u9669<\/p>\n

\u9885\u5185\u51fa\u8840\u75c5\u56e0\u5404\u5f02\uff0c\u60a3\u8005\u51fa\u8840\u590d\u53d1\u7387\u8f83\u666e\u901a\u4eba\u7fa4\u660e\u663e\u589e\u9ad8\uff3b<\/sup>3\uff0c10\uff3d<\/sup>\u3002\u81ea\u53d1\u6027\u8111\u51fa\u8840\u60a3\u8005\u7684\u5e74\u51fa\u8840\u590d\u53d1\u7387\u4e3a1.2%~3.0%\uff3b<\/sup>10\uff3d<\/sup>\uff0c\u7ea6\u4e3a\u666e\u901a\u4eba\u7fa4\u8111\u51fa\u8840\u98ce\u9669\u7684100\u500d\uff0c\u5176\u4e2d\u5f71\u54cd\u9885\u5185\u51fa\u8840\u590d\u53d1\u7684\u91cd\u8981\u56e0\u7d20\u4e3a\u9ad8\u8840\u538b\u3002\u4f46\u51fa\u8840\u590d\u53d1\u98ce\u9669\u53d7\u591a\u79cd\u56e0\u7d20\u5f71\u54cd\uff0c\u5982\u8111\u53f6\u51fa\u8840\uff084.4%\u6bd42.1%\uff09\u3001CAA\u76f8\u5173\u51fa\u8840\uff087.5%\u6bd41.1%\uff09\u53ca\u5fc3\u623f\u98a4\u52a8\u76f8\u5173\u8111\u51fa\u8840\uff084.2%\u6bd40.6%\uff09\u5747\u589e\u52a0\u4e86\u60a3\u8005\u9885\u5185\u51fa\u8840\u7684\u5e74\u590d\u53d1\u7387\uff3b<\/sup>38, 39, 40\uff3d<\/sup>\u3002\u4e14CAA\u76f8\u5173\u8111\u51fa\u8840\u60a3\u8005\u7684\u590d\u53d1\u7387\u4e0e\u5fae\u51fa\u8840\u7076\u6570\u76ee\u5448\u6b63\u76f8\u5173\uff3b<\/sup>39\uff3d<\/sup>\u3002\u6b64\u5916\uff0c\u8111\u6897\u6b7b\u540e\u51fa\u8840\u8f6c\u5316\u4e8b\u4ef6\u53ef\u80fd\u589e\u52a0\u4e86\u75c7\u72b6\u6027\u9885\u5185\u51fa\u8840\u7684\u98ce\u9669\uff082.8%\u6bd41.8%\uff09\uff3b<\/sup>41\uff3d<\/sup>\u3002<\/p>\n

\u9885\u5185\u51fa\u8840\u540e\u52a8\u8109\u8840\u6813\u4e8b\u4ef6\uff083.6%\u6bd41.1%\uff09\u53ca\u8111\u6897\u6b7b\uff081.1%~2.3%\u6bd40.5%\uff09\u7684\u5e74\u53d1\u75c5\u7387\u5747\u4e0a\u5347\uff0c\u4e3a\u666e\u901a\u4eba\u7fa4\u76844~6\u500d\uff3b<\/sup>8\uff0c42\uff3d<\/sup>\uff0c\u4e14\u5728\u5fc3\u623f\u98a4\u52a8\u60a3\u8005\u4e2d\u98ce\u9669\u8fdb\u4e00\u6b65\u589e\u9ad8\uff3b<\/sup>38\uff3d<\/sup>\u3002Murthy\u7b49\uff3b<\/sup>8\uff3d<\/sup>\u53d1\u73b0\u9885\u5185\u51fa\u8840\u589e\u52a0\u4e86\u8111\u6897\u6b7b\uff08HR=2.3\uff0c95%CI 1.7~3.1\uff09\u53ca\u5fc3\u808c\u6897\u6b7b\uff08HR=1.9\uff0c95%CI 1.2~2.9\uff09\u7684\u53d1\u751f\u98ce\u9669\u3002\u5728\u5fc3\u623f\u98a4\u52a8\u60a3\u8005\u4e2d\uff0c\u8111\u51fa\u8840\u589e\u52a0\u4e86\u8111\u6897\u6b7b\u3001\u77ed\u6682\u6027\u8111\u7f3a\u8840\u53d1\u4f5c\u53ca\u7cfb\u7edf\u6027\u8840\u6813\u7684\u5e74\u53d1\u75c5\u7387\uff3b9.59%\u6bd42.62%\uff0c\u7387\u6bd4\uff08rate ratio\uff09=3.67\uff0c95%CI 3.12~4.31\uff3d\uff3b<\/sup>43\uff3d<\/sup>\uff0c\u4e14\u4e0eCHA2<\/sub>DS2<\/sub>– VASc\u8bc4\u5206\u5448\u6b63\u76f8\u5173\uff083.2%~11.3%\uff09\uff3b<\/sup>40\uff3d<\/sup>\u3002Lerario\u7b49\uff3b<\/sup>44\uff3d<\/sup>\u53d1\u73b0\u5728\u4e0d\u540c\u5206\u7ea7\u7684CHA2<\/sub>DS2<\/sub>-VASc\u8bc4\u5206\u4e2d\uff0c\u8111\u51fa\u8840\u53ca\u786c\u819c\u4e0b\u51fa\u8840\u5747\u589e\u52a0\u4e86\u8111\u6897\u6b7b\u7684\u98ce\u9669\u3002\u7ecfCHA2<\/sub>DS2<\/sub>-VASc\u8bc4\u5206\u6821\u6b63\u540e\uff0c\u8111\u6897\u6b7b\u53d1\u75c5\u98ce\u9669\u5728\u8111\u51fa\u8840\uff08HR=2.8\uff0c95%CI 2.6~2.9\uff09\u548c\u786c\u819c\u4e0b\u51fa\u8840\uff08HR=1.6\uff0c95%CI 1.5~1.7\uff09\u540e\u5747\u589e\u52a0\uff3b<\/sup>44\uff3d<\/sup>\uff0c\u5176\u539f\u56e0\u53ef\u80fd\u4e0e\u505c\u7528\u6297\u51dd\u836f\u7269\u76f8\u5173\uff0c\u4f8b\u5982\u75c7\u72b6\u6027\u9759\u8109\u8840\u6813\u4e2d\u4f4d\u8d77\u75c5\u65f6\u95f4\u4e3a\u505c\u7528\u534e\u6cd5\u6797\u540e2\u5468\uff3b<\/sup>43\uff0c45\uff3d<\/sup>\u3002\u4ee5\u4e0a\u7814\u7a76\u6d89\u53ca\u7684\u5fc3\u623f\u98a4\u52a8\u60a3\u8005\u7684\u5e73\u5747\u5e74\u9f84\u4e3a72.6~76.2\u5c81\uff0c\u4e2d\u4f4dCHA2<\/sub>DS2<\/sub>-VASc\u8bc4\u5206\u4e3a4\u5206\u3002\u6700\u540e\uff0c\u7814\u7a76\u8005\u53d1\u73b0\u8111\u5fae\u51fa\u8840\u4e5f\u589e\u52a0\u4e86\u8111\u6897\u6b7b\u7684\u98ce\u9669\uff089.6%\u6bd45.6%\uff09\uff0c\u4e14\u4e0e\u5fae\u51fa\u8840\u7076\u6570\u76ee\u5448\u6b63\u76f8\u5173\uff3b<\/sup>32\uff3d<\/sup>\u3002<\/p>\n

\u9885\u5185\u51fa\u8840\u540c\u65f6\u589e\u52a0\u4e86\u8840\u6813\u6813\u585e\u53ca\u51fa\u8840\u590d\u53d1\u7684\u98ce\u9669\uff0c\u4f46\u53ef\u80fd\u51fa\u8840\u590d\u53d1\u7684\u98ce\u9669\u9ad8\u4e8e\u8111\u6897\u6b7b\u98ce\u9669\uff3b<\/sup>38\uff3d<\/sup>\u3002\u7136\u800c\uff0cMurthy\u7b49\uff3b<\/sup>8\uff3d<\/sup>\u53caLi\u4e0eMurthy\uff3b<\/sup>46\uff3d<\/sup>\u7684\u7814\u7a76\u5728\u6821\u6b63\u8111\u8840\u7ba1\u75c5\u5371\u9669\u56e0\u7d20\u540e\uff0c\u53d1\u73b0\u9885\u5185\u51fa\u8840\u989d\u5916\u589e\u52a0\u4e86\u8840\u6813\u6813\u585e\u7684\u98ce\u9669\u3002\u6b64\u5916\uff0c\u82e5\u5c06\u6297\u8840\u6813\u6cbb\u7597\u6307\u5f81\u7eb3\u5165\u5206\u6790\uff0c\u9885\u5185\u51fa\u8840\u540e\u8840\u6813\u6813\u585e\u7684\u98ce\u9669\u5c06\u8fdb\u4e00\u6b65\u589e\u9ad8\uff0c\u4f8b\u5982\u9885\u5185\u51fa\u8840\u4f34\u5fc3\u623f\u98a4\u52a8\u60a3\u8005\u7684\u8840\u6813\u6813\u585e\u98ce\u9669\u66f4\u9ad8\u3002\u4f46\u4e0a\u8ff0\u8bc1\u636e\u4e3a\u57fa\u4e8e\u4eba\u7fa4\u7814\u7a76\u7684\u7ed3\u8bba\uff0c\u5728\u4e34\u5e8a\u5b9e\u8df5\u4e2d\u9700\u8981\u7ed3\u5408\u60a3\u8005\u7684\u5177\u4f53\u60c5\u51b5\u4ee5\u8fdb\u4e00\u6b65\u8bc4\u4f30\u9885\u5185\u51fa\u8840\u540e\u51fa\u8840\u590d\u53d1\u53ca\u8840\u6813\u6813\u585e\u98ce\u9669\u3002<\/p>\n

\u56db\u3001\u91cd\u542f\u6297\u8840\u6813\u6cbb\u7597\u7684\u5fc5\u8981\u6027<\/p>\n

\u9885\u5185\u51fa\u8840\u589e\u52a0\u4e86\u989d\u5916\u7684\u8840\u6813\u6813\u585e\u98ce\u9669\uff3b<\/sup>46\uff3d<\/sup>\uff0c\u5fc3\u623f\u98a4\u52a8\u3001\u8111\u6897\u6b7b\u3001\u6df1\u9759\u8109\u8840\u6813\u7b49\u4ea6\u5747\u6709\u660e\u786e\u6297\u51dd\u6216\u6297\u8840\u5c0f\u677f\u7684\u6cbb\u7597\u6307\u5f81\uff0c\u8840\u6813\u6813\u585e\u98ce\u9669\u5728\u6b64\u7c7b\u60a3\u8005\u4e2d\u8fdb\u4e00\u6b65\u53e0\u52a0\uff0c\u5e94\u7528\u6297\u51dd\u6cbb\u7597\u53ca\u6297\u8840\u5c0f\u677f\u6cbb\u7597\u5341\u5206\u5fc5\u8981\u3002<\/p>\n

\uff08\u4e00\uff09\u6297\u51dd\u6cbb\u7597<\/p>\n

1.\u9885\u5185\u51fa\u8840\u5408\u5e76\u5fc3\u623f\u98a4\u52a8\uff1a\u4e00\u9879\u7eb3\u51652 452\u4f8b\u9885\u5185\u51fa\u8840\u4f34\u5fc3\u623f\u98a4\u52a8\u60a3\u8005\u89c2\u5bdf\u6027\u7814\u7a76\u7ed3\u679c\u7684\u835f\u8403\u5206\u6790\u53d1\u73b0\uff0c\u4e0e\u65e0\u6297\u8840\u6813\u6cbb\u7597\u76f8\u6bd4\uff0c\u7ef4\u751f\u7d20K\u62ee\u6297\u5242\u660e\u663e\u964d\u4f4e\u4e86\u8111\u6897\u6b7b\u7684\u98ce\u9669\uff083.2%\u6bd46.1%\uff0c\u7387\u6bd4=0.47\uff0c95%CI 0.29~0.77\uff09\uff0c\u4f46\u6297\u8840\u5c0f\u677f\u6cbb\u7597\u5e76\u672a\u964d\u4f4e\u8111\u6897\u6b7b\u98ce\u9669\uff089.5%\u6bd46.1%\uff0c\u7387\u6bd4=1.06\uff0c95%CI 0.72~1.54\uff09\u3002\u8fdb\u4e00\u6b65\u4e0e\u6297\u8840\u5c0f\u677f\u6cbb\u7597\u6bd4\u8f83\uff0c\u7ef4\u751f\u7d20K\u62ee\u6297\u5242\u4ecd\u964d\u4f4e\u4e86\u8111\u6897\u6b7b\u98ce\u9669\uff08\u7387\u6bd4=0.45\uff0c95%CI 0.27~0.74\uff09\u3002\u6b64\u7814\u7a76\u968f\u8bbf\u671f\u4e3a3\u4e2a\u6708\u4ee5\u4e0a\uff3b<\/sup>47\uff3d<\/sup>\u3002\u968f\u8bbf\u671f\u5ef6\u957f\u81f318\u4e2a\u6708\u7684MUCH-Italy\u7814\u7a76\u4e5f\u5f97\u51fa\u4e86\u7c7b\u4f3c\u7ed3\u8bba\uff0c\u5e76\u53d1\u73b0\u5728\u4e34\u5e8a\u5b9e\u8df5\u4e2d\u6297\u51dd\u6cbb\u7597\u4e0e\u6297\u8840\u5c0f\u677f\u6cbb\u7597\u7684\u60a3\u8005\u6bd4\u7387\u4e3a3\u22362\uff3b<\/sup>48\uff3d<\/sup>\u3002Nielsen\u7b49\uff3b<\/sup>49\uff3d<\/sup>\u5728\u968f\u8bbf1\u5e74\u7684\u961f\u5217\u4e2d\u53d1\u73b0\uff0c\u4e0e\u672a\u53e3\u670d\u6297\u51dd\u836f\u7269\u7684\u60a3\u8005\u76f8\u6bd4\uff0c\u53e3\u670d\u6297\u51dd\u836f\u7269\u6709\u964d\u4f4e\u8111\u6897\u6b7b\/\u7cfb\u7edf\u6027\u8840\u6813\u53d1\u75c5\u7387\u7684\u8d8b\u52bf\uff08HR=0.59\uff0c95%CI 0.33~1.03\uff09\uff0c\u4e14\u663e\u8457\u964d\u4f4e\u4e86\u5168\u56e0\u6b7b\u4ea1\u98ce\u9669\uff08HR=0.55\uff0c95%CI 0.37~0.82\uff09\u53ca\u8111\u6897\u6b7b\/\u7cfb\u7edf\u6027\u8840\u6813\/\u5168\u56e0\u6b7b\u4ea1\u590d\u5408\u7ec8\u70b9\u7684\u53d1\u751f\u98ce\u9669\uff08HR=0.55\uff0c95%CI 0.39~0.78\uff09\u3002\u7136\u800c\uff0c\u82e5\u4ee5\u8840\u6813\u6813\u585e\u4e8b\u4ef6\u53ca\u4e25\u91cd\u51fa\u8840\u4e3a\u590d\u5408\u7ec8\u70b9\u6307\u6807\uff0c\u53e3\u670d\u6297\u51dd\u836f\u7269\u5e76\u672a\u6539\u5584\u4e34\u5e8a\u7ed3\u5c40\uff0811.5%\u6bd47.9%\uff0cP=0.154\uff09\uff1b\u82e5\u6539\u5584\u4e34\u5e8a\u7ed3\u5c40\uff0c\u9700\u8981\u6c42\u6cbb\u7597\u8fbe\u6807\u7387\uff08INR\u4e3a2.0~3.0\uff09\u226560%\uff3b<\/sup>50\uff3d<\/sup>\u3002<\/p>\n

\u6b64\u5916\uff0c\u81ea\u53d1\u6027\u9885\u5185\u51fa\u8840\u540e\u91cd\u542f\u6297\u51dd\u6cbb\u7597\u7684\u7814\u7a76\u6d89\u53ca\u7684\u836f\u7269\u591a\u4e3a\u7ef4\u751f\u7d20K\u62ee\u6297\u5242\uff0c\u90e8\u5206\u60a3\u8005\u63a5\u53d7\u65b0\u578b\u53e3\u670d\u6297\u51dd\u836f\u7269\u6cbb\u7597\u3002\u867d\u7136\u4e0e\u534e\u6cd5\u6797\u76f8\u6bd4\uff0c\u65b0\u578b\u53e3\u670d\u6297\u51dd\u836f\u964d\u4f4e\u4e86\u5fc3\u623f\u98a4\u52a8\u60a3\u8005\u9885\u5185\u9996\u6b21\u51fa\u8840\u98ce\u9669\uff08HR=0.42\uff0c95%CI 0.31~0.58\uff09\u53ca\u4f4f\u9662\u75c5\u6b7b\u7387\uff08OR=0.75\uff0c97.5%CI 0.69~0.81\uff09\uff3b<\/sup>22\uff0c51\uff3d<\/sup>\uff0c\u4f46\u4e24\u8005\u964d\u4f4e\u9885\u5185\u51fa\u8840\u540e\u8840\u6813\u6813\u585e\u98ce\u9669\u7684\u4f18\u52a3\u5c1a\u4e0d\u660e\u786e\u3002<\/p>\n

\u6700\u540e\uff0c\u5982\u4f55\u7b5b\u9009\u9002\u5408\u91cd\u542f\u6297\u51dd\u6cbb\u7597\u7684\u60a3\u8005\uff0c\u76ee\u524d\u5c1a\u65e0\u5b9a\u8bba\u3002\u4f46\u90e8\u5206\u7814\u7a76\u53d1\u73b0\u5177\u6709\u4e0b\u8ff0\u7279\u70b9\u7684\u60a3\u8005\u53ef\u80fd\u4ece\u91cd\u542f\u6297\u51dd\u6cbb\u7597\u4e2d\u83b7\u76ca\uff1a\uff081\uff09CHA2<\/sub>DS2<\/sub>-VASc\u8bc4\u5206\u22656\u5206\uff3b<\/sup>40\uff3d<\/sup>\uff1b\uff082\uff09\u5e73\u5747\u5e74\u9f8478\u5c81\uff0cCHA2<\/sub>DS2<\/sub>-VASc\u8bc4\u52063.9\u5206\uff0cHAS-BLED\u8bc4\u52063.2\u5206\uff3b<\/sup>49\uff3d<\/sup>\u3002<\/p>\n

2.\u9885\u5185\u51fa\u8840\u5408\u5e76\u975e\u5fc3\u623f\u98a4\u52a8\uff1a\u5c3d\u7ba1\u591a\u6570\u7814\u7a76\u5747\u9488\u5bf9\u5fc3\u623f\u98a4\u52a8\u4eba\u7fa4\u5c55\u5f00\uff0c\u4f46Murthy\u7b49\uff3b<\/sup>52\uff3d<\/sup>\u7cfb\u7edf\u5206\u6790\u4e86\u6240\u6709\u5177\u6709\u6297\u51dd\u6cbb\u7597\u6307\u5f81\u76845 306\u4f8b\u8111\u51fa\u8840\u60a3\u8005\uff0c\u5305\u62ec\u5fc3\u623f\u98a4\u52a8\u3001\u4eba\u5de5\u5fc3\u810f\u74e3\u819c\u3001\u9759\u8109\u6813\u585e\u53ca\u8111\u6897\u6b7b\u60a3\u8005\uff0c\u5e73\u5747\u968f\u8bbf\u65f6\u95f4\u57281\u5e74\u4ee5\u4e0a\uff0c\u53d1\u73b0\u53e3\u670d\u6297\u51dd\u6cbb\u7597\u663e\u8457\u964d\u4f4e\u4e86\u60a3\u8005\u7684\u8840\u6813\u6813\u585e\u98ce\u9669\uff08RR=0.34\uff0c95%CI 0.25~0.45\uff09\u3002<\/p>\n

3.\u8111\u6897\u6b7b\u540e\u51fa\u8840\u8f6c\u5316\uff1a\u8111\u6897\u6b7b\u540e\u9885\u5185\u51fa\u8840\u8f6c\u5316\u589e\u52a0\u4e86\u60a3\u8005\u7684\u6b8b\u75be\u53ca\u6b7b\u4ea1\u98ce\u9669\uff0c\u9010\u6b65\u53d7\u5230\u56fd\u5185\u53ca\u56fd\u9645\u5b66\u8005\u7684\u91cd\u89c6\u3002\u4f46\u5173\u4e8e\u51fa\u8840\u8f6c\u5316\u540e\u4f55\u65f6\u542f\u52a8\u6297\u8840\u6813\u6cbb\u7597\u5c1a\u65e0\u660e\u786e\u63a8\u8350\u610f\u89c1\uff3b<\/sup>9\uff0c29\uff3d<\/sup>\u3002Paciaroni\u7b49\uff3b<\/sup>41\uff3d<\/sup>\u53d1\u73b0\u5fc3\u623f\u98a4\u52a8\u60a3\u8005\u4e2d\u8111\u6897\u6b7b\u540e\u51fa\u8840\u8f6c\u5316\u5e76\u672a\u589e\u52a0\u7f3a\u8840\u4e8b\u4ef6\u7684\u98ce\u9669\uff084.6%\u6bd44.9%\uff09\uff1bNishimoto\u7b49\uff3b<\/sup>53\uff3d<\/sup>\u5728\u8840\u7ba1\u5185\u6cbb\u7597\u76f8\u5173\u51fa\u8840\u60a3\u8005\u7684\u7814\u7a76\u4e2d\u53d1\u73b0\uff0c\u65e0\u51fa\u8840\u8f6c\u5316\u7ec4\u3001\u51fa\u8840\u6027\u6897\u6b7b\u7ec4\u53ca\u8111\u5b9e\u8d28\u51fa\u8840\u7ec430 d\u5185\u8111\u6897\u6b7b\u7684\u590d\u53d1\u7387\u5206\u522b\u4e3a3.7%\u30016.3%\u53ca15.4%\uff0c\u7ec4\u95f4\u5dee\u5f02\u65e0\u7edf\u8ba1\u5b66\u610f\u4e49\uff0c\u4f46\u51fa\u8840\u8f6c\u5316\u6709\u589e\u52a0\u8111\u6897\u6b7b\u590d\u53d1\u98ce\u9669\u7684\u8d8b\u52bf\u3002\u800c\u5728\u5fc3\u623f\u98a4\u52a8\u76f8\u5173\u7684\u8111\u6897\u6b7b\u540e\u6297\u51dd\u836f\u7269\u7684\u9009\u62e9\u65b9\u9762\uff0c\u4e0e\u65b0\u578b\u53e3\u670d\u6297\u51dd\u836f\u76f8\u6bd4\uff0c\u7ef4\u751f\u7d20K\u62ee\u6297\u5242\u589e\u52a0\u4e86\u7f3a\u8840\u4e8b\u4ef6\u7684\u590d\u53d1\u98ce\u9669\uff08OR=2.89\uff0c95%CI 1.66~4.80\uff09\uff3b<\/sup>41\uff3d<\/sup>\u3002<\/p>\n

4.\u521b\u4f24\u6027\u8111\u51fa\u8840\uff1a\u521b\u4f24\u6027\u8111\u51fa\u8840\u4e0e\u81ea\u53d1\u6027\u8111\u51fa\u8840\u7684\u673a\u5236\u4e0d\u540c\u3002Albrecht\u7b49\uff3b<\/sup>54\uff3d<\/sup>\u56de\u987e\u6027\u5206\u6790\u4e8610 782\u4f8b\u521b\u4f24\u6027\u8111\u635f\u4f24\u60a3\u8005\u7684\u4e34\u5e8a\u8d44\u6599\uff0c\u60a3\u8005\u5e73\u5747\u5e74\u9f84\u4e3a81.3\u5c81\uff0c82%\u5b58\u5728\u5fc3\u623f\u98a4\u52a8\uff0c\u7814\u7a76\u53d1\u73b0\u534e\u6cd5\u6797\u964d\u4f4e\u4e86\u60a3\u8005\u53d1\u751f\u8840\u6813\u6813\u585e\u4e8b\u4ef6\u7684\u98ce\u9669\uff0811.4%\u6bd415.6%\uff0cRR=0.77\uff0c95%CI 0.67~0.88\uff09\uff0c\u4e5f\u964d\u4f4e\u4e86\u8111\u6897\u6b7b\u7684\u53d1\u75c5\u98ce\u9669\uff08RR=0.81\uff0c95%CI 0.69~0.95\uff09\u53ca\u9759\u8109\u8840\u6813\u7684\u53d1\u751f\u7387\uff082.6%\u6bd45.5%\uff09\u3002\u800cNielsen\u7b49\uff3b<\/sup>55\uff3d<\/sup>\u5efa\u7acb\u4e86\u5e73\u5747\u5e74\u9f84\u4e3a77.4\u5c81\u7684\u4f34\u5fc3\u623f\u98a4\u52a8\u7684\u521b\u4f24\u6027\u9885\u5185\u51fa\u8840\u60a3\u8005\u961f\u5217\uff0c\u968f\u8bbf9\u4e2a\u6708\u540e\u53d1\u73b0\u91cd\u542f\u534e\u6cd5\u6797\u6cbb\u7597\u53ef\u663e\u8457\u964d\u4f4e\u60a3\u8005\u7684\u5168\u56e0\u6b7b\u4ea1\u98ce\u9669\uff0c\u5e76\u6709\u964d\u4f4e\u8111\u6897\u6b7b\/\u7cfb\u7edf\u6027\u6813\u585e\u98ce\u9669\u7684\u8d8b\u52bf\uff08HR=0.4\uff0c95%CI 0.4~1.11\uff09\u3002<\/p>\n

\uff08\u4e8c\uff09\u6297\u8840\u5c0f\u677f\u6cbb\u7597<\/p>\n

\u5fc3\u623f\u98a4\u52a8\u60a3\u8005\u8111\u51fa\u8840\u540e\u6297\u8840\u5c0f\u677f\u6cbb\u7597\u5e76\u672a\u964d\u4f4e\u5176\u8840\u6813\u6813\u585e\u98ce\u9669\uff3b<\/sup>47\uff0c49\uff3d<\/sup>\uff0c\u6297\u8840\u5c0f\u677f\u6cbb\u7597\u7684\u7597\u6548\u663e\u8457\u5f31\u4e8e\u6297\u51dd\u6cbb\u7597\u3002\u97e9\u56fd\u4e00\u9879\u4e2d\u4f4d\u968f\u8bbf\u65f6\u95f4\u4e3a2.5\u5e74\u7684\u961f\u5217\u7814\u7a76\u53d1\u73b0\uff0c\u4e0d\u8bba\u662f\u5426\u5b58\u5728\u6297\u8840\u5c0f\u677f\u6cbb\u7597\u75c5\u53f2\uff0c\u9885\u5185\u51fa\u8840\u540e\u6297\u8840\u5c0f\u677f\u6cbb\u7597\u5747\u672a\u964d\u4f4e\u60a3\u8005\u7684\u975e\u81f4\u6b7b\u6027\u8111\u6897\u6b7b\u98ce\u9669\uff08HR=0.74\uff0c95%CI 0.30~1.80\uff09\uff3b<\/sup>19\uff3d<\/sup>\u3002RESTART\u7814\u7a76\u7eb3\u5165\u6297\u8840\u6813\u6cbb\u7597\u4e0b\u7684\u8111\u51fa\u8840\u60a3\u8005\u8fdb\u884c\u968f\u673a\u5bf9\u7167\u8bd5\u9a8c\uff0c\u5176\u4e2d72%\u4e3a\u5fc3\u623f\u98a4\u52a8\u60a3\u8005\uff0c\u57282\u5e74\u7684\u968f\u8bbf\u671f\u4e2d\uff0c\u6297\u8840\u5c0f\u677f\u6cbb\u7597\u5e76\u672a\u964d\u4f4e\u4e3b\u8981\u8840\u7ba1\u6813\u585e\u4e8b\u4ef6\u7684\u53d1\u751f\u7387\uff0815%\u6bd414%\uff0cHR=1.02\uff0c95%CI 0.65~1.60\uff09\uff1b\u6b64\u5916\uff0c\u5728\u8111\u51fa\u8840\u65f6\u670d\u7528\u6297\u8840\u5c0f\u677f\u836f\u7269\u4e9a\u7ec4\u4e2d\uff0c\u51fa\u8840\u540e\u6297\u8840\u5c0f\u677f\u6cbb\u7597\u4e5f\u672a\u80fd\u964d\u4f4e\u8840\u7ba1\u6813\u585e\u4e8b\u4ef6\u7684\u98ce\u9669\uff08HR=1.21\uff0c95%CI 0.71~2.08\uff09\uff3b<\/sup>56\uff3d<\/sup>\u3002\u6709\u7814\u7a76\u5728\u5177\u6709\u6297\u51dd\u6cbb\u7597\u6307\u5f81\u7684\u60a3\u8005\u4e2d\u9009\u62e9\u91cd\u542f\u6297\u8840\u5c0f\u677f\u6cbb\u7597\uff0c\u6821\u6b63\u6df7\u6742\u56e0\u7d20\u540e\u53d1\u73b0\u6297\u8840\u5c0f\u677f\u6cbb\u7597\u5e76\u672a\u964d\u4f4e\u8840\u6813\u6813\u585e\u4e8b\u4ef6\uff08\u5fc3\u808c\u6897\u6b7b\u3001\u8111\u6897\u6b7b\u3001\u5916\u5468\u52a8\u8109\u8840\u6813\u3001\u9759\u8109\u8840\u6813\u53ca\u80ba\u6813\u585e\uff09\u7684\u98ce\u9669\uff08HR=0.99\uff0c95%CI 0.75~1.31\uff09\uff0c\u6b64\u7814\u7a76\u968f\u8bbf\u671f\u4e3a2.3\u5e74\uff3b<\/sup>57\uff3d<\/sup>\u3002<\/p>\n

\u4f46\u662f\uff0c\u4e00\u9879\u7eb3\u5165\u89c2\u5bdf\u6027\u7814\u7a76\u7684\u835f\u8403\u5206\u6790\u7ed3\u679c\u63d0\u793a\uff0c\u6297\u8840\u5c0f\u677f\u6cbb\u7597\u53ef\u964d\u4f4e\u8111\u6897\u6b7b\u7684\u53d1\u751f\u7387\uff08RR=0.61\uff0c95%CI 0.48~0.79\uff09\uff3b<\/sup>58\uff3d<\/sup>\uff0c\u5176\u6709\u6548\u6027\u53ca\u5b89\u5168\u6027\u6709\u5f85\u968f\u673a\u5bf9\u7167\u8bd5\u9a8c\u8fdb\u4e00\u6b65\u9a8c\u8bc1\u3002<\/p>\n

\u4e94\u3001\u91cd\u542f\u6297\u8840\u6813\u6cbb\u7597\u4e0e\u9885\u5185\u51fa\u8840\u590d\u53d1\u98ce\u9669<\/p>\n

\u4ece\u9884\u9632\u8840\u6813\u6813\u585e\u4e8b\u4ef6\u6216\u8111\u6897\u6b7b\u7684\u89d2\u5ea6\u51fa\u53d1\uff0c\u9885\u5185\u51fa\u8840\u540e\u5e94\u5728\u5177\u6709\u6297\u8840\u6813\u6cbb\u7597\u6307\u5f81\u7684\u60a3\u8005\u4e2d\uff0c\u6839\u636e\u6307\u5357\u610f\u89c1\u542f\u52a8\u6297\u51dd\u6216\u6297\u8840\u5c0f\u677f\u6cbb\u7597\uff3b<\/sup>16\uff3d<\/sup>\u3002\u4f46\u5728\u4e34\u5e8a\u5b9e\u8df5\u4e2d\uff0c\u9885\u5185\u51fa\u8840\u7684\u590d\u53d1\u98ce\u9669\u5219\u6210\u4e3a\u4e0d\u542f\u52a8\u6297\u8840\u6813\u6cbb\u7597\u7684\u6700\u5927\u969c\u788d\uff3b<\/sup>17\uff3d<\/sup>\u3002\u76ee\u524d\u7814\u7a76\u7ed3\u679c\u503e\u5411\u4e8e\u6297\u51dd\u6216\u6297\u8840\u6813\u6cbb\u7597\u5e76\u672a\u589e\u52a0\u9885\u5185\u51fa\u8840\u590d\u53d1\u98ce\u9669\uff0c\u4f46\u4e5f\u6709\u7814\u7a76\u5f97\u51fa\u4e0d\u540c\u7ed3\u8bba\u3002<\/p>\n

\uff08\u4e00\uff09\u6297\u8840\u6813\u6cbb\u7597\u7684\u5b89\u5168\u6027<\/p>\n

CHIRONE\u7814\u7a76\u7eb3\u5165\u4e86\u9885\u5185\u51fa\u8840\u540e\u91cd\u542f\u6297\u51dd\u6cbb\u7597\u7684\u60a3\u8005267\u4f8b\uff0c\u4e2d\u4f4d\u5e74\u9f84\u4e3a73.9\u5c81\uff0c\u4e2d\u4f4d\u968f\u8bbf\u65f6\u95f4\u4e3a2\u5e74\uff0c\u60a3\u8005\u7684\u9996\u6b21\u51fa\u8840\u75c5\u56e0\u4e2d\u81ea\u53d1\u6027\u51fa\u8840\u536038.5%\uff0c\u6297\u51dd\u6cbb\u7597\u6307\u5f81\u5404\u5f02\uff08\u5fc3\u623f\u98a4\u52a8\u536045.3%\uff09\uff0c\u91cd\u542f\u6297\u51dd\u6cbb\u7597\u540e\u9885\u5185\u51fa\u8840\u7684\u5e74\u590d\u53d1\u7387\u4e3a2.56%\uff0c\u5176\u4e2d25%\u7684\u60a3\u8005\u6b7b\u4ea1\uff0c\u590d\u53d1\u76f8\u5173\u56e0\u7d20\u65e0\u6cd5\u660e\u786e\uff1b\u51fa\u8840\u590d\u53d1\u8ddd\u91cd\u542f\u6297\u51dd\u6cbb\u7597\u7684\u4e2d\u4f4d\u65f6\u95f4\u4e3a28.5 d\uff081~ 333 d\uff09\uff3b<\/sup>59\uff3d<\/sup>\u3002\u4f462.56%\u7684\u5e74\u51fa\u8840\u590d\u53d1\u7387\u5e76\u4e0d\u660e\u663e\u9ad8\u4e8e\u524d\u8ff0\u9885\u5185\u51fa\u8840\u540e\u7684\u81ea\u7136\u590d\u53d1\u7387\u3002\u591a\u9879\u89c2\u5bdf\u6027\u7814\u7a76\u7ed3\u679c\u63d0\u793a\uff1a\uff081\uff09\u5fc3\u623f\u98a4\u52a8\u3001\u4eba\u5de5\u5fc3\u810f\u74e3\u819c\u3001\u9759\u8109\u8840\u6813\u53ca\u8111\u6897\u6b7b\u60a3\u8005\u91cd\u542f\u6297\u51dd\u6cbb\u7597\u5747\u672a\u589e\u52a0\u9885\u5185\u51fa\u8840\u7684\u98ce\u9669\uff3b<\/sup>47\uff0c52\uff0c60\uff3d<\/sup>\uff1b\uff082\uff09\u5fc3\u623f\u98a4\u52a8\u60a3\u8005\u91cd\u542f\u6297\u51dd\u6cbb\u7597\u7684\u5b89\u5168\u6027\u4e0d\u53d7\u9996\u6b21\u9885\u5185\u51fa\u8840\u7c7b\u578b\uff08\u8111\u51fa\u8840\u3001\u786c\u819c\u4e0b\u51fa\u8840\u6216\u86db\u7f51\u819c\u4e0b\u8154\u51fa\u8840\uff09\u7684\u5f71\u54cd\uff08HR=0.46\uff0c95%CI 0.11~1.88\uff09\uff3b<\/sup>60\uff3d<\/sup>\uff1b\uff083\uff09\u7ef4\u751f\u7d20K\u62ee\u6297\u5242\u53ca\u65b0\u578b\u53e3\u670d\u6297\u51dd\u836f\u5747\u672a\u589e\u52a0\u9885\u5185\u51fa\u8840\u7684\u590d\u53d1\u98ce\u9669\uff3b<\/sup>57\uff3d<\/sup>\u3002<\/p>\n

\u6b64\u5916\uff0c\u89c2\u5bdf\u6027\u7814\u7a76\u7684\u835f\u8403\u5206\u6790\u7ed3\u679c\u8bc1\u5b9e\u4e86\u9885\u5185\u51fa\u8840\u540e\u957f\u671f\u6297\u8840\u5c0f\u677f\u6cbb\u7597\u7684\u5b89\u5168\u6027\uff08RR=0.77\uff0c95%CI 0.47~1.25\uff09\uff3b<\/sup>47\uff3d<\/sup>\u3002\u4e00\u9879\u968f\u673a\u5bf9\u7167\u8bd5\u9a8cRESTART\u7814\u7a76\u7ed3\u679c\u8fdb\u4e00\u6b65\u8bc1\u5b9e\uff0c\u6297\u8840\u5c0f\u677f\u6cbb\u7597\u672a\u589e\u52a0\u9885\u5185\u51fa\u8840\u7684\u590d\u53d1\u98ce\u9669\uff084.0%\u6bd49.0%\uff0cHR=0.51\uff0c95%CI 0.25~1.03\uff09\uff3b<\/sup>56\uff3d<\/sup>\uff0c\u8be5\u7ed3\u8bba\u4e0e\u771f\u5b9e\u4e16\u754c\u4e2d\u7684\u957f\u671f\u968f\u8bbf\u7ed3\u679c\u4e00\u81f4\uff3b<\/sup>19\uff0c40\uff3d<\/sup>\u3002<\/p>\n

\u518d\u6b21\uff0c\u4e34\u5e8a\u5b9e\u8df5\u4e2d\u66f4\u5927\u7684\u6311\u6218\u4e3a\u662f\u5426\u5728\u9ad8\u51fa\u8840\u98ce\u9669\u60a3\u8005\u4e2d\u91cd\u542f\u6297\u8840\u6813\u6cbb\u7597\u3002Nielsen\u7b49\uff3b<\/sup>49\uff3d<\/sup>\u53d1\u73b0\u5728\u5e73\u5747HAS-BLED\u8bc4\u5206\u4e3a3.2\u5206\u7684\u60a3\u8005\u4e2d\u91cd\u542f\u6297\u51dd\uff088.0%\u6bd48.6%\uff09\u53ca\u6297\u8840\u5c0f\u6cbb\u7597\uff085.3%\u6bd48.6%\uff09\u5747\u672a\u589e\u52a0\u9885\u5185\u51fa\u8840\u590d\u53d1\u7684\u98ce\u9669\u3002<\/p>\n

\u6700\u540e\uff0c\u591a\u9879\u7814\u7a76\u7ed3\u679c\u5747\u63d0\u793a\u81ea\u53d1\u6027\u9885\u5185\u51fa\u8840\u540e\u542f\u52a8\u6297\u51dd\u53ca\u6297\u8840\u5c0f\u677f\u6cbb\u7597\u5747\u672a\u589e\u52a0\u5168\u8eab\u4e25\u91cd\u51fa\u8840\u7684\u98ce\u9669\uff082.5%~7.0%\u6bd40~9.0%\uff09\uff3b<\/sup>19\uff0c43\uff0c48\uff0c50\uff0c56, 57\uff3d<\/sup>\u3002<\/p>\n

\uff08\u4e8c\uff09\u6297\u8840\u6813\u6cbb\u7597\u7684\u98ce\u9669<\/p>\n

\u53e6\u6709\u591a\u9879\u7814\u7a76\u7ed3\u679c\u63d0\u793a\u91cd\u542f\u6297\u51dd\u6cbb\u7597\u589e\u52a0\u4e86\u9885\u5185\u51fa\u8840\u7684\u590d\u53d1\u98ce\u9669\u3002Majeed\u7b49\uff3b<\/sup>45\uff3d<\/sup>\u53d1\u73b0\u5728\u5e73\u5747\u5e74\u9f8476\u5c81\u7684\u534e\u6cd5\u6797\u76f8\u5173\u8111\u51fa\u8840\u60a3\u8005\u4e2d\uff0c\u91cd\u542f\u534e\u6cd5\u6797\u6cbb\u7597\u589e\u52a0\u4e86\u60a3\u8005\u7684\u9885\u5185\u51fa\u8840\u98ce\u9669\uff08HR=5.6\uff0c95%CI 1.8~17.2\uff09\u3002Little\u7b49\uff3b<\/sup>61\uff3d<\/sup>\u5219\u7eb3\u5165\u4e86\u6d88\u5316\u9053\u51fa\u8840\uff0863.3%\uff09\u3001\u9885\u5185\u51fa\u8840\uff0811.9%\uff09\u53ca\u5176\u4ed6\u7c7b\u578b\u51fa\u8840\uff0825.0%\uff09\u7684\u60a3\u8005\uff0c\u4e2d\u4f4d\u5e74\u9f84\u4e3a82\u5c81\uff0c\u5e73\u5747HAS-BLED\u8bc4\u5206\u4e3a3.3\u5206\uff0c\u968f\u8bbf82~83\u5468\uff0c\u5176\u4e2d57%\u7684\u60a3\u8005\u63a5\u53d7\u534e\u6cd5\u6797\u6cbb\u7597\uff0c43%\u63a5\u53d7\u65b0\u578b\u53e3\u670d\u6297\u51dd\u836f\u6cbb\u7597\uff0c\u7ed3\u679c\u63d0\u793a\u91cd\u542f\u53e3\u670d\u6297\u51dd\u6cbb\u7597\u589e\u52a0\u4e86\u60a3\u8005\u7684\u5168\u8eab\u51fa\u8840\u98ce\u9669\uff08HR=2.20\uff0c95%CI 1.36~3.56\uff09\uff0c\u5176\u4e2d\u9885\u5185\u51fa\u8840\u5360\u6bd432.5%\u3002Park\u7b49\uff3b<\/sup>50\uff3d<\/sup>\u7814\u7a76\u53d1\u73b0\u8111\u51fa\u8840\u7684\u590d\u53d1\u5747\u53d1\u751f\u4e8e\u91cd\u542f\u6297\u51dd\u6cbb\u7597\u7ec4\u4e2d\uff0c\u4f46\u5dee\u5f02\u65e0\u7edf\u8ba1\u5b66\u610f\u4e49\u3002\u8111\u6897\u6b7b\u51fa\u8840\u8f6c\u5316\u540e\u542f\u52a8\u6297\u51dd\u6cbb\u7597\u53ef\u80fd\u589e\u52a0\u4e86\u75c7\u72b6\u6027\u9885\u5185\u51fa\u8840\u7684\u98ce\u9669\uff0c\u4f46\u4e5f\u6709\u7814\u7a76\u8ba4\u4e3a\u65b0\u578b\u53e3\u670d\u6297\u51dd\u836f\u5e76\u672a\u589e\u52a0\u9885\u5185\u51fa\u8840\u98ce\u9669\uff3b<\/sup>41\uff0c53\uff3d<\/sup>\u3002<\/p>\n

\uff08\u4e09\uff09\u7279\u5b9a\u75c5\u56e0\u7684\u9885\u5185\u51fa\u8840<\/p>\n

CAA\u76f8\u5173\u8111\u51fa\u8840\u540e\u662f\u5426\u542f\u52a8\u6297\u51dd\u6cbb\u7597\u66f4\u5177\u4e89\u8bae\u3002\u5728CAA\u76f8\u5173\u8111\u51fa\u8840\u60a3\u8005\u7684\u81ea\u7136\u961f\u5217\u4e2d\uff0c\u9885\u5185\u51fa\u8840\u7684\u590d\u53d1\u7387\u663e\u8457\u9ad8\u4e8e\u5176\u4ed6\u75c5\u56e0\u7684\u9885\u5185\u51fa\u8840\uff3b<\/sup>39\uff3d<\/sup>\uff0c\u5e74\u590d\u53d1\u7387\u53ef\u8fbe8.9%\uff3b<\/sup>62\uff3d<\/sup>\u3002HAS-BLED\u8bc4\u5206\u65e0\u6cd5\u9884\u6d4b\u6297\u51dd\u6cbb\u7597\u540eCAA\u60a3\u8005\u7684\u9885\u5185\u51fa\u8840\u98ce\u9669\uff3b<\/sup>63\uff3d<\/sup>\u3002\u56e0\u6b64\uff0c\u5373\u4f7fCAA\u5e76\u672a\u589e\u52a0\u5fc3\u623f\u98a4\u52a8\u60a3\u8005\u81ea\u53d1\u6027\u8111\u51fa\u8840\u7684\u6b7b\u4ea1\u98ce\u9669\uff3b<\/sup>64\uff3d<\/sup>\uff0c\u4f46\u76f8\u5173\u7814\u7a76\u7ed3\u679c\u63d0\u793a\u4e0d\u5efa\u8bae\u5728CAA\u60a3\u8005\u4e2d\u542f\u52a8\u6297\u8840\u6813\u6cbb\u7597\uff0c\u751a\u81f3\u63d0\u793a\u5728\u5fae\u51fa\u8840\u7076\u22652\u4e2a\u7684CAA\u60a3\u8005\u4e2d\u5e94\u8c28\u614e\u8bc4\u4f30\u51fa\u8840\u98ce\u9669\uff3b<\/sup>65\uff3d<\/sup>\u3002<\/p>\n

\u521b\u4f24\u6027\u9885\u5185\u51fa\u8840\u60a3\u8005\u91cd\u542f\u6297\u51dd\u6cbb\u7597\u7684\u51fa\u8840\u98ce\u9669\u540c\u6837\u4e0d\u5bb9\u5ffd\u89c6\u3002\u7eb3\u5165\u521b\u4f24\u6027\u9885\u5185\u51fa\u8840\u60a3\u8005\u7684CHIRONE\u7814\u7a76\u672a\u53d1\u73b0\u6297\u51dd\u6cbb\u7597\u589e\u52a0\u4e86\u60a3\u8005\u9885\u5185\u51fa\u8840\u590d\u53d1\u7684\u98ce\u9669\u3002Nielsen\u7b49\uff3b<\/sup>55\uff3d<\/sup>\u751a\u81f3\u53d1\u73b0\u91cd\u542f\u534e\u6cd5\u6797\u6cbb\u7597\u53ef\u964d\u4f4e\u8111\u51fa\u8840\u7684\u53d1\u751f\u98ce\u9669\uff08HR=0.51\uff0c95%CI 0.37~0.71\uff09\u3002Albrecht\u7b49\uff3b<\/sup>54\uff3d<\/sup>\u4e5f\u5f97\u51fa\u7c7b\u4f3c\u7ed3\u8bba\uff0c\u4f46\u540c\u65f6\u53d1\u73b0\u6297\u51dd\u6cbb\u7597\u589e\u52a0\u4e86\u60a3\u8005\u5168\u8eab\u4e25\u91cd\u51fa\u8840\u7684\u98ce\u9669\uff0812.0%\u6bd48.6%\uff09\u3002Staerk\u7b49\uff3b<\/sup>65\uff3d<\/sup>\u53d1\u73b0\u7ef4\u751f\u7d20K\u62ee\u6297\u5242\u589e\u52a0\u4e86\u4e25\u91cd\u51fa\u8840\u7684\u98ce\u9669\uff08HR=1.30\uff0c95%CI 1.03~1.64\uff09\uff0c\u4f46\u662f\u65b0\u578b\u53e3\u670d\u6297\u51dd\u836f\u5e76\u672a\u589e\u52a0\u4e25\u91cd\u51fa\u8840\u7684\u98ce\u9669\uff08HR=1.15\uff0c95%CI 0.81~ 1.63\uff09\uff3b<\/sup>66\uff3d<\/sup>\u3002<\/p>\n

\uff08\u56db\uff09\u9885\u5185\u51fa\u8840\u590d\u53d1\u98ce\u9669\u76f8\u5173\u7814\u7a76\u7684\u5c40\u9650\u6027<\/p>\n

\u4e34\u5e8a\u533b\u5e08\u5c06\u91cd\u542f\u6297\u8840\u6813\u6cbb\u7597\u89c6\u4e3a\u9885\u5185\u51fa\u8840\u7684\u5173\u952e\u56e0\u7d20\uff0c\u4f46\u9885\u5185\u51fa\u8840\u590d\u53d1\u53d7\u591a\u79cd\u56e0\u7d20\u5f71\u54cd\uff0c\u5305\u62ec\u60a3\u8005\u5e74\u9f84\u3001\u9996\u6b21\u51fa\u8840\u75c5\u56e0\u3001\u6297\u51dd\u6cbb\u7597\u6307\u5f81\u3001\u6297\u8840\u5c0f\u677f\u6cbb\u7597\u6307\u5f81\u3001\u51fa\u8840\u98ce\u9669\u53ca\u8840\u538b\u7ba1\u7406\u7b49\uff3b<\/sup>62\uff0c67\uff3d<\/sup>\u3002Yeh\u7b49\uff3b<\/sup>68\uff3d<\/sup>\u53d1\u73b0\u6839\u636eSMASH-U\u5206\u578b\uff0c\u5927\u90e8\u5206\u590d\u53d1\u6027\u8111\u51fa\u8840\u4e0e\u9996\u6b21\u8111\u51fa\u8840\u7684\u75c5\u7406\u7c7b\u578b\u4e00\u81f4\uff0881.6%\uff09\uff0c\u800c\u836f\u7269\u539f\u56e0\u53ef\u80fd\u53ea\u536012.5%\u3002\u56e0\u6b64\uff0c\u51fa\u8840\u590d\u53d1\u7684\u5177\u4f53\u75c5\u56e0\u9700\u8981\u8fdb\u4e00\u6b65\u5206\u6790\uff0c\u800c\u76ee\u524d\u7814\u7a76\u5747\u5c06\u51fa\u8840\u590d\u53d1\u5f52\u56e0\u4e8e\u6297\u8840\u6813\u6cbb\u7597\uff0c\u53ef\u80fd\u9020\u6210\u4e86\u6297\u8840\u6813\u6cbb\u7597\u589e\u52a0\u4e86\u9885\u5185\u51fa\u8840\u98ce\u9669\u7684\u5047\u8c61\u3002\u4f46\u53e6\u4e00\u65b9\u9762\uff0c\u91cd\u542f\u6297\u8840\u6813\u6cbb\u7597\u7684\u5b9e\u9645\u6bd4\u4f8b\u4e0e\u4e34\u5e8a\u533b\u5e08\u7684\u91cd\u542f\u610f\u613f\u5b58\u5728\u5de8\u5927\u5dee\u8ddd\uff0c\u771f\u5b9e\u4e16\u754c\u4e2d\u53ef\u80fd\u4ec5\u5728\u4f4e\u51fa\u8840\u98ce\u9669\u60a3\u8005\u4e2d\u91cd\u542f\u4e86\u6297\u8840\u6813\u6cbb\u7597\uff0c\u9020\u6210\u4e86\u91cd\u542f\u6297\u8840\u6813\u6cbb\u7597\u672a\u589e\u52a0\u51fa\u8840\u590d\u53d1\u98ce\u9669\u7684\u5047\u8c61\u3002\u867d\u7136\u591a\u56e0\u7d20\u5206\u6790\u53ca\u835f\u8403\u5206\u6790\u7ed3\u679c\u5747\u8bc1\u5b9e\u4e86\u6297\u8840\u6813\u6cbb\u7597\u7684\u5b89\u5168\u6027\uff0c\u4f46\u8bc1\u636e\u7ea7\u522b\u504f\u4f4e\uff3b<\/sup>16\uff0c69\uff3d<\/sup>\uff0c\u5728\u4e34\u5e8a\u5b9e\u8df5\u4e2d\u4ecd\u9700\u8c28\u614e\u89e3\u8bfb\u3002\u6700\u540e\uff0c\u65e2\u5f80\u7814\u7a76\u5747\u672a\u660e\u786e\u51fa\u8840\u590d\u53d1\u6e90\u4e8e\u9996\u6b21\u51fa\u8840\u7684\u540e\u9057\u6548\u5e94\u8fd8\u662f\u6e90\u4e8e\u6297\u8840\u6813\u6cbb\u7597\u3002\u82e5\u540e\u7eed\u7814\u7a76\u80fd\u8fdb\u4e00\u6b65\u660e\u786e\u5176\u56e0\u679c\u5173\u7cfb\uff0c\u5c06\u6709\u52a9\u4e8e\u6b64\u7c7b\u60a3\u8005\u7684\u4e2a\u4f53\u5316\u6cbb\u7597\u3002<\/p>\n

\u516d\u3001\u91cd\u542f\u6297\u8840\u6813\u6cbb\u7597\u7684\u65f6\u673a\u53ca\u65b9\u6848<\/p>\n

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\u65e9\u671f\u6216\u665a\u671f\u542f\u52a8\u6297\u51dd\u6cbb\u7597\u7684\u6838\u5fc3\u95ee\u9898\u662f\u5982\u4f55\u5e73\u8861\u51fa\u8840\u4e0e\u8840\u6813\u6813\u585e\u7684\u98ce\u9669\uff0c\u4f46\u9885\u5185\u51fa\u8840\u540e\u60a3\u8005\u8840\u6813\u6813\u585e\u4e8b\u4ef6\u53ca\u9885\u5185\u51fa\u8840\u590d\u53d1\u7684\u65f6\u95f4\u5e76\u4e0d\u660e\u786e\uff3b<\/sup>46\uff3d<\/sup>\u3002Murthy\u7b49\uff3b<\/sup>52\uff3d<\/sup>\u7814\u7a76\u53d1\u73b0\u4e34\u5e8a\u5b9e\u8df5\u4e2d\u91cd\u542f\u6297\u51dd\u7684\u5e73\u5747\u65f6\u95f4\u4e3a10 d\u81f32\u4e2a\u6708\uff1bMajeed\u7b49\uff3b<\/sup>45\uff3d<\/sup>\u5219\u63d0\u51fa\u9885\u5185\u51fa\u8840\u540e10~30\u5468\u4e3a\u6700\u4f73\u91cd\u542f\u65f6\u95f4\uff0c\u800c\u5728\u4e34\u5e8a\u5b9e\u8df5\u4e2d\uff0c\u4e2d\u4f4d\u91cd\u542f\u65f6\u95f4\u4e3a5.6\uff082.6\uff0c17.0\uff09\u5468\u3002\u4e39\u9ea6\u7684\u4e00\u9879\u961f\u5217\u7814\u7a76\u7ed3\u679c\u5219\u63d0\u793a\uff0c\u91cd\u542f\u6297\u51dd\u6cbb\u7597\u7684\u4e2d\u4f4d\u65f6\u95f4\u4e3a34 d\uff3b<\/sup>49\uff3d<\/sup>\uff0c\u800cCHIRONE\u7814\u7a76\u4e2d\u60a3\u8005\u91cd\u542f\u6297\u51dd\u6cbb\u7597\u7684\u4e2d\u4f4d\u65f6\u95f4\u4e3a60 d\uff3b<\/sup>59\uff3d<\/sup>\u3002\u4f46\u6297\u51dd\u6cbb\u7597\u7684\u91cd\u542f\u65f6\u95f4\u4e5f\u53d7\u51fa\u8840\u539f\u56e0\u53ca\u6297\u51dd\u6cbb\u7597\u6307\u5f81\u7684\u5f71\u54cd\uff1a\uff081\uff09\u51fa\u8840\u539f\u56e0\u65b9\u9762\uff1a\u8111\u51fa\u8840\u60a3\u8005\u6297\u51dd\u6cbb\u7597\u7684\u4e2d\u4f4d\u91cd\u542f\u65f6\u95f4\u4e3a4.4\u5468\uff0c\u786c\u819c\u4e0b\u51fa\u8840\u60a3\u8005\u4e3a6.4\u5468\uff3b<\/sup>45\uff3d<\/sup>\uff0c\u8111\u6897\u6b7b\u540e\u51fa\u8840\u8f6c\u5316\u60a3\u8005\u7684\u91cd\u542f\u65f6\u95f4\u4e3a3~23.3 d\uff0c\u6bd4\u65e0\u51fa\u8840\u8f6c\u5316\u60a3\u8005\u665a12 d\uff3b<\/sup>41\uff0c53\uff3d<\/sup>\uff1b\uff082\uff09\u6297\u51dd\u6cbb\u7597\u6307\u5f81\u65b9\u9762\uff1a\u6297\u51dd\u6cbb\u7597\u7684\u4e2d\u4f4d\u91cd\u542f\u65f6\u95f4\u5728\u9759\u8109\u8840\u6813\u3001\u4e8c\u5c16\u673a\u68b0\u74e3\u3001\u4e3b\u52a8\u8109\u673a\u68b0\u74e3\u53ca\u5fc3\u623f\u98a4\u52a8\u60a3\u8005\u4e2d\u4f9d\u6b21\u5ef6\u957f\uff0c\u4e3a2.3~9.2\u5468\uff3b<\/sup>45\uff3d<\/sup>\u3002\u4f46\u591a\u9879\u7814\u7a76\u7ed3\u679c\u63d0\u793a\u60a3\u8005\u7684\u6297\u51dd\u6cbb\u7597\u5747\u4e8e\u9885\u5185\u51fa\u8840\u540e\u534a\u5e74\u5185\u542f\u52a8\u3002<\/p>\n

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