{"id":52564,"date":"2025-06-03T05:11:01","date_gmt":"2025-06-03T05:11:01","guid":{"rendered":"http:\/\/zydq.1006ss.com\/?p=52564"},"modified":"2025-06-03T05:11:01","modified_gmt":"2025-06-03T05:11:01","slug":"%e8%82%be%e5%b0%8f%e7%90%83%e6%bb%a4%e8%bf%87%e7%8e%87%e5%92%8c%e5%86%85%e7%94%9f%e8%82%8c%e9%85%90%e6%b8%85%e9%99%a4%e7%8e%87%ef%bc%8c%e6%82%a8%e5%88%86%e5%be%97%e6%b8%85%e6%a5%9a%e5%90%97%ef%bc%9f","status":"publish","type":"post","link":"http:\/\/zydq.1006ss.com\/?p=52564","title":{"rendered":"\u80be\u5c0f\u7403\u6ee4\u8fc7\u7387\u548c\u5185\u751f\u808c\u9150\u6e05\u9664\u7387\uff0c\u60a8\u5206\u5f97\u6e05\u695a\u5417\uff1f"},"content":{"rendered":"

\u4e0d\u77e5\u4f60\u662f\u5426\u7559\u610f\u8fc7\u5bf9\u4e8e\u80be\u529f\u80fd\u7684\u8868\u8ff0\uff0c\u6709\u7684\u4f7f\u7528\u80be\u5c0f\u7403\u6ee4\u8fc7\u7387\uff08glomerular filtrationg rate\uff0cGFR\uff09\uff0c\u6709\u7684\u5219\u4f7f\u7528\u5185\u751f\u808c\u9150\u6e05\u9664\u7387\uff08Creatinine Clearance rate, Ccr\uff09\u3002\u8fd9\u4e0b\u95ee\u9898\u6765\u4e86\u2014\u2014GFR\u548cCcr\u4e4b\u95f4\u6709\u533a\u522b\u5417\uff1f\u5bf9\u4e8e\u80be\u810f\u529f\u80fd\u68c0\u6d4b\uff0cCREA\u7684\u63d0\u793a\u610f\u4e49\u5341\u5206\u91cd\u8981\uff0c\u4f46\u5355\u7eaf\u7684CREA\u7684\u68c0\u6d4b\u7ed3\u679c\u4e5f\u4e0d\u662f\u4e34\u5e8a\u6700\u7ec8\u9700\u6c42\u7684\u7ed3\u679c\uff0c\u5176\u8fd8\u662f\u8981\u6362\u7b97\u4e3a\u80be\u5c0f\u7403\u6ee4\u8fc7\u7387\/\u808c\u9150\u6e05\u9664\u7387\u7684\uff0c\u4ee5\u8fd9\u4e9b\u6307\u6807\u53bb\u8861\u91cf\u80be\u810f\u7684\u529f\u80fd\uff0c\u4eca\u5929\u5c31\u8bf4\u8bf4\u8fd9\u4e24\u4e2a\u6307\u6807\uff0c\u770b\u770b\u6709\u6ca1\u6709\u4ec0\u4e48\u6536\u83b7\u3002<\/p>\n

PART01\uff1a\u80be\u5c0f\u7403\u6ee4\u8fc7\u7387\uff08GFR\uff09\u2014\u2014\u4ec0\u4e48\u662f\u80be\u5c0f\u7403\u6ee4\u8fc7\u7387<\/p>\n

\u6307\u80be\u810f\u5728\u5355\u4f4d\u65f6\u95f4\u5185\uff0c\u751f\u6210\u539f\u5c3f\u7684\u91cf\uff0c\u7528mL\/min\u8868\u793a\uff0c\u6210\u4eba\u9759\u606f\u72b6\u6001\u4e0b\u7537\u6027\u7ea6\u4e3a120mL\/ (min\u00b71.732<\/sup>)\uff0c\u5973\u6027\u7ea6\u4f4e10%\u3002GFR\u4e0e\u5e74\u9f84\u6709\u5173\uff0c25~30\u5c81\u65f6\u8fbe\u5230\u9ad8\u5cf0\uff0c\u6b64\u540e\u968f\u5e74\u9f84\u589e\u957f\u800c\u9010\u6e10\u964d\u4f4e\u3002<\/p>\n

\u80be\u810f\u901a\u8fc7\u5c3f\u7684\u5f62\u6210\u548c\u6392\u51fa\uff0c\u8c03\u8282\u6c34\u3001\u7535\u89e3\u8d28\u3001\u4f53\u6db2\u6e17\u900f\u538b\u3001\u52a8\u8109\u8840\u538b\u3001\u9178\u78b1\u5e73\u8861\u7b49\uff0c\u7ef4\u6301\u5185\u73af\u5883\u7684\u7a33\u5b9a\u3002\u5c3f\u7684\u751f\u6210\u5305\u62ec\u4e09\u4e2a\u57fa\u672c\u8fc7\u7a0b\uff1a<\/p>\n

1\uff09\u8840\u6d46\u5728\u80be\u5c0f\u7403\u6bdb\u7ec6\u8840\u7ba1\u5904\u7684\u6ee4\u8fc7\uff08\u9664\u4e86\u86cb\u767d\u8d28\u5916\uff0c\u51e0\u4e4e\u6240\u6709\u7684\u6210\u5206\u5747\u80fd\u88ab\u6ee4\u5165\u80be\u5c0f\u7403\u56ca\u8154\uff0c\u5f62\u6210\u8d85\u6ee4\u6db2\uff0c\u4e5f\u79f0\u539f\u5c3f\uff09\uff1b<\/p>\n

2\uff09\u539f\u5c3f\u5728\u6d41\u7ecf\u80be\u5c0f\u7ba1\u548c\u96c6\u5408\u7ba1\u7684\u8fc7\u7a0b\u4e2d\u88ab\u9009\u62e9\u6027\u91cd\u5438\u6536\uff1b<\/p>\n

3\uff09\u80be\u5c0f\u7ba1\u548c\u96c6\u5408\u7ba1\u7684\u5206\u6ccc\uff0c\u6700\u540e\u5f62\u6210\u7ec8\u5c3f\u3002<\/p>\n

\u80be\u5c0f\u7403\u6ee4\u8fc7\u662f\u5c3f\u751f\u6210\u7684\u7b2c\u4e00\u6b65\uff0c\u56e0\u800c\uff0c\u80be\u5c0f\u7403\u7684\u6ee4\u8fc7\u529f\u80fd\u662f\u8bc4\u4ef7\u80be\u529f\u80fd\u7684\u91cd\u8981\u6307\u6807\u3002<\/p>\n

 \u80be\u5c0f\u7403\u793a\u610f\u56fe<\/sup><\/p>\n

PART02\uff1a\u80be\u5c0f\u7403\u6ee4\u8fc7\u7387\uff08GFR\uff09\u2014\u2014\u4e34\u5e8a\u5e94\u7528<\/p>\n

    \u6162\u6027\u80be\u810f\u75c5\uff08CKD\uff09\u7684\u56fd\u9645\u5206\u671f\u662f\u6309\u80be\u5c0f\u7403\u6ee4\u8fc7\u7387\u6765\u5212\u5206\u7684\uff0c\u5171\u5206\u4e94\u671f\uff1a<\/p>\n<\/p>\n

      \u2605\u9700\u8981\u6ce8\u610f\u7684\u662f\u80be\u5c0f\u7403\u6ee4\u8fc7\u7387\u4e0e\u5e74\u9f84\u3001\u6027\u522b\u53ca\u4f53\u683c\u76f8\u5173\uff0c\u6240\u4ee5\u4e2a\u4f53\u5dee\u5f02\u5f88\u5927\u3002\u4e00\u822c\u8ba4\u4e3a\u53ea\u8981\u80be\u5c0f\u7403\u6ee4\u8fc7\u7387\uff1e90ml\/min\uff0c\u5c31\u57fa\u672c\u53ef\u4ee5\u8ba4\u4e3a\u80be\u529f\u80fd\u6ca1\u6709\u53d7\u635f\u3002<\/p>\n

      \u2605\u4e00\u822c\u60c5\u51b5\u4e0b40\u5c81\u5f00\u59cb\uff0c\u80be\u529f\u80fd\u5c31\u4f1a\u9010\u5e74\u4e0b\u964d\uff0c\u6700\u76f4\u89c2\u7684\u6570\u636e\u5c31\u662f\u80be\u5c0f\u7403\u6ee4\u8fc7\u7387\u6bcf\u5e74\u964d\u4f4e0.8-1.1ml\/min\u3002<\/p>\n

       \u2605\u4e0a\u8ff0\u8868\u683c\u7684\u75c5\u7406\u5206\u7ea7\uff0c\u8fd9\u4e2a\u4e0e\u6b63\u5e38\u80be\u529f\u80fd\u7684\u5206\u7ea7\u4e0d\u540c\uff0c\u5176\u662f\u9488\u5bf9\u5df2\u7ecf\u660e\u786e\u6709\u80be\u810f\u635f\u4f24\u7684\u60a3\u8005\uff0c\u800c\u5bf9\u4e8e\u4e00\u4f4d\u5065\u5eb7\u7684\u8001\u5e74\u4eba\uff0c\u5982\u679c\u6ca1\u6709\u76f4\u63a5\u80be\u635f\u4f24\u8bc1\u636e\uff0c\u53ea\u8981\u80be\u5c0f\u7403\u6ee4\u8fc7\u7387\u5927\u4e8e60ml\/min\uff0c\u5373\u53ef\u8ba4\u4e3a\u662f\u6b63\u5e38\u7684\uff0c\u662f\u751f\u7406\u6027\u7684\u4e0b\u964d\u3002<\/p>\n

PART03\uff1a\u80be\u5c0f\u7403\u6ee4\u8fc7\u7387\uff08GFR\uff09\u2014\u2014\u600e\u4e48\u8ba1\u7b97<\/p>\n

GFR\u4e0d\u80fd\u76f4\u63a5\u6d4b\u5b9a\uff0c\u53ea\u80fd\u7528\u67d0\u79cd\u6807\u5fd7\u7269\u7684\u80be\u810f\u6e05\u9664\u7387\u6765\u4ee3\u66ff\u6216\u901a\u8fc7\u516c\u5f0f\u63a8\u7b97\u3002\u56e0\u6b64\uff0c\u4f7f\u7528\u4e0d\u540c\u7684\u6807\u5fd7\u7269\uff0c\u5c31\u4ea7\u751f\u4e86\u4e0d\u540c\u7684\u8ba1\u7b97\u65b9\u6cd5\uff0c\u5e38\u7528\u7684\u662f\u56db\u7c7b\uff0c\u63a8\u7b97\u7684GFR\uff0c\u7b80\u79f0eGFR\uff0c\u5355\u4f4dml\/min\/1.73m2\u3002 <\/p>\n

\u2605\u83ca\u7c89\u6e05\u9664\u7387\uff1a\u53cd\u6620GFR\u7684\u201c\u91d1\u6807\u51c6\u201d\uff0c\u7ed3\u679c\u51c6\u786e\u53ef\u9760\uff0c\u4f46\u6d4b\u5b9a\u65b9\u6cd5\u590d\u6742\u3001\u6602\u8d35\uff0c\u5e38\u4e0d\u88ab\u4e34\u5e8a\u91c7\u7528\uff0c\u4e3b\u8981\u7528\u4e8e\u5b9e\u9a8c\u5ba4\u7814\u7a76\u3002<\/p>\n

\u2605\u80be\u52a8\u6001\u5f71\u50cf\uff1a\u5e38\u7528\u8bd5\u524299mTc-DTPA\uff0c\u7075\u654f\u5ea6\u9ad8\uff0c\u53ef\u4e0e\u83ca\u7c89\u6e05\u9664\u7387\u5ab2\u7f8e\uff0c\u4f46\u8d39\u7528\u9ad8\uff0c\u653e\u5c04\u6027\uff0c\u9002\u7528\u8303\u56f4\u6709\u9650\u3002<\/p>\n

\u2605\u808c\u9150\u6e05\u9664\u7387\uff08Ccr\uff09\uff1a\u808c\u9150\u53ef\u4ee5\u5168\u90e8\u7531\u80be\u5c0f\u7403\u6ee4\u8fc7\uff0c\u4f46\u80be\u5c0f\u7ba1\u548c\u96c6\u5408\u7ba1\u80fd\u5206\u6ccc\u5c11\u91cf\u7684\u808c\u9150\uff0c\u4e5f\u53ef\u91cd\u5438\u6536\u5c11\u91cf\u7684\u808c\u9150\uff0c\u56e0\u6b64\uff0c\u5982\u679c\u9700\u8981\u7279\u522b\u7cbe\u786e\u5730\u8ba1\u7b97GFR\uff0c\u4e0d\u80fd\u76f4\u63a5\u7528Ccr\u7684\u503c\u6765\u4ee3\u66ff\uff0c\u662f\u6309\u4ee5\u4e0b\u516c\u5f0f\u6765\u8ba1\u7b97\u3002<\/p>\n

eGFR=Ccr\u00d70.84\u00d71.73\/BSA\uff1b<\/p>\n

CCr=\u3010\uff08140-\u5e74\u9f84\uff09\u00d7\u4f53\u91cd\uff08KG\uff09\u00d70.85\uff08\u5973\u6027\uff09\u3011\/\uff0872\u00d7scr\uff09\uff1b<\/p>\n

BSA\uff08m2\uff09=0.007184\u00d7\u4f53\u91cd\uff08kg\uff09\u00d70.425\u00d7\u8eab\u9ad8\uff08cm\uff09\u00d70.725\uff1b<\/p>\n

\u9700\u8981\u6ce8\u610f\uff1a\u5f53eGFR\u662f15-60ml\/min\/1.73m2\u65f6\u6700\u51c6\u786e\uff0c\u80a5\u80d6\u60a3\u8005GFR\u88ab\u4f4e\u4f30\uff0c\u5f53BMI\uff1c25\u65f6GFR\u88ab\u4f4e\u4f30\u3002<\/p>\n

\u2605\u7ecf\u8fc71.73m2\u7684\u4f53\u8868\u9762\u79ef\u6807\u51c6\u5316\u5e76\u7528MDRD\u516c\u5f0f\u8ba1\u7b97\uff1a\u8ba1\u7b97\u7528\u751f\u5316\u68c0\u6d4b\u6307\u6807\u4e3b\u8981\u6709\u8840\u6e05\u808c\u9150\u3001\u8840\u5c3f\u7d20\u6c2e\u3001\u8840\u6e05\u80f1\u6291\u7d20C\u7b49\uff0c\u5e38\u7528\u516c\u5f0f\u662fCKD-EPI\u548c\u6539\u826f\u4e2d\u56fd\u4ebaMDRD\u3002<\/p>\n

\u25bcCKD-EPI\u516c\u5f0f\uff1a<\/p>\n

\u25cf\u7537\u6027\uff1a<\/p>\n

\u8840\u6e05\u808c\u9150\u22640.9ml\/dl\uff0ceGFR=144\u00d7\uff08\u8840\u6e05\u808c\u9150\/0.9\uff09- 0.411\u00d70.993\u00d7\u5e74\u9f84<\/p>\n

\u8840\u6e05\u808c\u9150>0.9ml\/dl\uff0ceGFR=144\u00d7\uff08\u8840\u6e05\u808c\u9150\/0.9\uff09- 1.209\u00d70.993\u00d7\u5e74\u9f84<\/p>\n

\u25cf\u5973\u6027\uff1a<\/p>\n

\u8840\u6e05\u808c\u9150\u22640.7ml\/dl\uff0ceGFR=144\u00d7\uff08\u8840\u6e05\u808c\u9150\/0.7\uff09- 0.329\u00d70.993\u00d7\u5e74\u9f84<\/p>\n

\u8840\u6e05\u808c\u9150>0.7ml\/dl\uff0ceGFR=144\u00d7\uff08\u8840\u6e05\u808c\u9150\/0.7\uff09- 1.209\u00d70.993\u00d7\u5e74\u9f84<\/p>\n

     \u9700\u8981\u6ce8\u610f\uff1a\u5728eGFR\uff1c60ml\/min\/1.73m2\u7684\u60a3\u8005\u4e2d\uff0c\u51c6\u786e\u6027\u4f18\u4e8eCG\u548cMDRD\u516c\u5f0f\u3002<\/p>\n

\u25bcMDRD\u516c\u5f0f\uff1a<\/p>\n

\u25cfeGFR=170\u00d7\u8840\u6e05\u808c\u9150\uff08mg\/dl\uff09-0.999\u00d7\u5e74\u9f84-0.176\u00d7\u8840\u5c3f\u7d20\u6c2e\uff08mg\/dl\uff09-0.170\u00d7\u8840\u6d46\u767d\u86cb\u767d\uff08g\/dl\uff09-0.318\u00d7\uff080.742\u5973\u6027\uff09<\/p>\n

\u25cf\u6539\u826f\u7684MDRD\u516c\u5f0f\uff1aeGFR=170\u00d7\u8840\u6e05\u808c\u9150\uff08mg\/dl\uff09-1.234\u00d7\u5e74\u9f84-0.179\u00d7\uff080.79\u5973\u6027\uff09<\/p>\n

      \u9700\u8981\u6ce8\u610f\uff1a\u5f53eGFR\u662f15-60ml\/min\/1.73m2\u65f6\u6700\u51c6\u786e\uff0c\u5f53GFR\uff1e60 ml\/min\/1.73m2\u65f6GFR\u88ab\u4f4e\u4f30\uff1b\u5728GFR\u6b63\u5e38\u6216\u63a5\u8fd1\u6b63\u5e38\u3001\u5e74\u9f84\u548c\u4f53\u91cd\u6781\u7aef\u3001\u622a\u80a2\u8005\u3001\u5b55\u5987\u548c\u809d\u786c\u5316\u4eba\u7fa4\u4e2d\u4e0d\u592a\u51c6\u786e\u3002<\/p>\n

PART04\uff1a\u808c\u9150\u6e05\u9664\u7387\uff08CCR\uff09\u2014\u2014\u4ec0\u4e48\u662f\u808c\u9150\u6e05\u9664\u7387<\/p>\n

\u524d\u9762\u8bb2\u5230\uff0cGFR\u6307\u7684\u662f\u5355\u4f4d\u65f6\u95f4\u5185\u53cc\u80be\u751f\u6210\u8d85\u6ee4\u6db2\u7684\u91cf\uff0c\u5373\u53cc\u80be\u5728\u5355\u4f4d\u65f6\u95f4\uff08min\uff09\u5185\u5c06\u82e5\u5e72\u4f53\u79ef\uff08mL\uff09\u8840\u6d46\u4e2d\u6240\u542b\u7684\u67d0\u79cd\u7269\u8d28\u5168\u90e8\u6e05\u9664\u3002\u5982\u679c\u8981\u51c6\u786e\u6d4b\u5b9aGFR\uff0c\u53ef\u4ee5\u901a\u8fc7\u6d4b\u5b9a\u67d0\u79cd\u7269\u8d28\u5355\u4f4d\u65f6\u95f4\u5185\u4ece\u5c3f\u4e2d\u6392\u51fa\u7684\u603b\u91cf\uff0c\u9664\u4ee5\u8840\u6d46\u4e2d\u8be5\u7269\u8d28\u7684\u6d53\u5ea6\u6765\u7b97\u5f97\u3002\u8fd9\u79cd\u7269\u8d28\u5e94\u8be5\u5177\u6709\u4ee5\u4e0b\u7279\u6027\uff1a<\/p>\n

1\uff09\u8840\u6d46\u4e2d\u7684\u8be5\u7269\u8d28\u80fd\u7ecf\u80be\u5c0f\u7403\u81ea\u7531\u6ee4\u8fc7\uff0c\u5728\u80be\u5c0f\u56ca\u8d85\u6ee4\u6db2\u4e2d\u7684\u6d53\u5ea6\u4e0e\u8840\u6d46\u6d53\u5ea6\u76f8\u540c\uff1b<\/p>\n

2\uff09\u5b83\u5728\u80be\u5c0f\u7ba1\u548c\u96c6\u5408\u7ba1\u4e2d\u65e2\u4e0d\u88ab\u91cd\u5438\u6536\uff0c\u4e5f\u4e0d\u88ab\u5206\u6ccc\u3002<\/p>\n

\u83ca\u7c89\u5c31\u662f\u4e00\u79cd\u5b8c\u5168\u7b26\u5408\u4e0a\u8ff0\u6761\u4ef6\u7684\u7269\u8d28\uff0c\u56e0\u6b64\u83ca\u7c89\u7684\u6e05\u9664\u7387\u53ef\u7528\u6765\u4ee3\u8868GFR\u3002<\/p>\n

\u5e94\u7528\u83ca\u7c89\u6d4b\u5b9aGFR\u867d\u51c6\u786e\u53ef\u9760\uff0c\u4f46\u64cd\u4f5c\u4e0d\u4fbf\uff0c\u5e76\u4e0d\u9002\u7528\u4e8e\u4e34\u5e8a\uff0c\u6545\u4e34\u5e8a\u5e38\u4f1a\u9000\u800c\u6c42\u5176\u6b21\uff0c\u7528Ccr\u6765\u5927\u81f4\u8bc4\u4f30GFR\u3002\u808c\u9150\u53ef\u4ee5\u5168\u90e8\u7531\u80be\u5c0f\u7403\u6ee4\u8fc7\uff0c\u4f46\u80be\u5c0f\u7ba1\u548c\u96c6\u5408\u7ba1\u80fd\u5206\u6ccc\u5c11\u91cf\u7684\u808c\u9150\uff0c\u4e5f\u53ef\u91cd\u5438\u6536\u5c11\u91cf\u7684\u808c\u9150\uff0c\u56e0\u6b64\uff0c\u5982\u679c\u9700\u8981\u7279\u522b\u7cbe\u786e\u5730\u8ba1\u7b97GFR\uff0c\u4e0d\u80fd\u76f4\u63a5\u7528Ccr\u7684\u503c\u6765\u4ee3\u66ff\u3002<\/p>\n

\u9664\u4e86Ccr\u4e4b\u5916\uff0c\u4e34\u5e8a\u4e2d\u6709\u65f6\u4e5f\u4f1a\u7528\u534a\u80f1\u6c28\u9178\u86cb\u767d\u9176\u6291\u5236\u5242C\u6e05\u9664\u7387\u6765\u8bc4\u4f30GFR\uff0c\u534a\u80f1\u6c28\u9178\u86cb\u767d\u9176\u6291\u5236\u5242C\u53c8\u88ab\u79f0\u4e3a\u80f1\u6291\u7d20 C(Cys C)\uff0c\u5c5e\u4e8e\u534a\u80f1\u6c28\u9178\u86cb\u767d\u9176\u6291\u5236\u5242\u5bb6\u65cf\u3002\u4eba\u4f53\u5185\u5404\u79cd\u6709\u6838\u7ec6\u80de\u5747\u53ef\u751f\u6210Cys C\u4e14\u5206\u6ccc\u901f\u7387\u6052\u5b9a\uff0c\u5e76\u4e14Cys C\u4e0d\u53d7\u5e74\u9f84\u3001\u4f53\u91cd\u3001\u708e\u75c7\u7b49\u5916\u5728\u56e0\u7d20\u7684\u5f71\u54cd\uff0c\u91cd\u8981\u7684\u662f\u80be\u5c0f\u7403\u662f\u5176\u552f\u4e00\u7684\u4ee3\u8c22\u9014\u5f84\uff0c\u56e0\u6b64\u5f53\u60a3\u8005\u80be\u810f\u529f\u80fd\u53d7\u635f\u65f6\uff0c\u8840\u6e05Cys C\u7684\u6d53\u5ea6\u4e5f\u4f1a\u76f8\u5e94\u53d1\u751f\u6539\u53d8\uff0c\u4e14\u4e0eGFR\u5448\u73b0\u826f\u597d\u7684\u7ebf\u6027\u5173\u7cfb\u3002\u7531\u4e8eCys C\u5206\u5b50\u91cf\u8f83\u4f4e\uff0c\u53ef\u65e0\u963b\u788d\u901a\u8fc7\u80be\u5c0f\u7403\u57fa\u5e95\u819c\u4ece\u800c\u7ecf\u80be\u5c0f\u7403\u81ea\u7531\u6ee4\u8fc7\uff0c\u867d\u5728\u8fd1\u66f2\u5c0f\u7ba1\u4e2d\u88ab\u91cd\u5438\u6536\u4f46\u5438\u6536\u540e\u88ab\u5b8c\u5168\u4ee3\u8c22\uff0c\u4e0d\u91cd\u65b0\u8fd4\u56de\u5230\u8840\u6db2\u4e2d\uff0c\u56e0\u6b64\u8840\u6e05Cys C\u6d53\u5ea6\u5b8c\u5168\u7531\u80be\u5c0f\u7403\u6ee4\u8fc7\u529f\u80fd\u51b3\u5b9a\uff0c\u8840\u6e05Cys C\u4e0e\u8840\u6e05\u808c\u9150\u76f8\u6bd4\uff0c\u5177\u6709\u7279\u5f02\u6027\u3001\u654f\u611f\u6027\u8f83\u9ad8\u7b49\u7279\u70b9\uff0c\u6545\u4e34\u5e8a\u4e2d\u5e38\u5c06\u5176\u4f5c\u4e3a\u8bc4\u5b9aGFR\u7684\u4e00\u4e2a\u7075\u654f\u4e14\u7279\u5f02\u7684\u6307\u6807\u3002<\/p>\n

GFR\u7684\u8ba1\u7b97\u65b9\u6cd5<\/sup><\/p>\n

        \u808c\u9150\u6709\u5916\u6e90\u6027\u548c\u5185\u6e90\u6027\u4e24\u79cd\uff0c\u5916\u6e90\u6027\u808c\u9150\u662f\u8089\u7c7b\u98df\u7269\u5728\u4f53\u5185\u4ee3\u8c22\u540e\u7684\u4ea7\u7269\uff0c\u5185\u6e90\u6027\u808c\u9150\u662f\u4f53\u5185\u808c\u8089\u7ec4\u7ec7\u4ee3\u8c22\u7684\u4ea7\u7269\u3002CCR\u6307\u80be\u810f\u5728\u5355\u4f4d\u65f6\u95f4\u5185\uff0c\u5bf9\u8840\u6db2\u4e2d\u808c\u9150\u7684\u6e05\u9664\u80fd\u529b\u3002\u5728\u5916\u6e90\u6027\u808c\u9150\u6444\u5165\u6052\u5b9a\u7684\u60c5\u51b5\u4e0b\uff0c\u808c\u9150\u6e05\u9664\u7387\u80fd\u591f\u771f\u5b9e\u7684\u53cd\u6620\u80be\u5c0f\u7403\u7684\u6ee4\u8fc7\u529f\u80fd\uff0c\u662f\u76ee\u524d\u4e34\u5e8a\u4e0a\u6700\u5e38\u7528\u7684\u80be\u529f\u80fd\u8bd5\u9a8c\u3002\u6b63\u5e38\u503c\uff1a\u6bcf\u5206\u949f80-120ml\/min\u3002<\/p>\n

PART05\uff1a\u808c\u9150\u6e05\u9664\u7387\uff08CCR\uff09\u2014\u2014\u4e34\u5e8a\u5e94\u7528<\/p>\n

\u2605\u5224\u65ad\u80be\u5c0f\u7403\u529f\u80fd\u6709\u65e0\u635f\u5bb3\u53ca\u5176\u7a0b\u5ea6\u3002\u2002<\/p>\n<\/p>\n

\u2605\u6307\u5bfc\u4e34\u5e8a\u7528\u836f\u548c\u6cbb\u7597\u3002\u2002\u2002\u2002<\/p>\n

\u2605\u80be\u79fb\u690d\u60a3\u8005\u5185\u751f\u808c\u9150\u6e05\u9664\u7387\u9010\u6b65\u56de\u5347\u8868\u660e\u79fb\u690d\u6210\u529f\uff0c\u53cd\u4e4b\u63d0\u793a\u6709\u6392\u5f02\u53cd\u5e94\u3002\u2002\u2002\u2002<\/p>\n

\u2605\u5065\u5eb7\u4eba\u968f\u7740\u5e74\u9f84\u589e\u957f\uff0c\u80be\u5b9e\u8d28\u4f53\u79ef\u7f29\u5c0f\uff0c\u5185\u751f\u808c\u9150\u6e05\u9664\u7387\u53ef\u6709\u6240\u964d\u4f4e\uff0c\u8001\u5e74\u4eba\u51cf\u4f4e\u53ef\u8fbe60ml\/min\u3002\u2002\u2002\u2002<\/p>\n

\u2605\u5176\u4ed6\uff1a\u7532\u72b6\u817a\u529f\u80fd\u51cf\u9000\u75c7\u3001\u80be\u6027\u9ad8\u8840\u538b\u3001\u5267\u70c8\u8fd0\u52a8\u53ca\u4f7f\u7528\u67d0\u4e9b\u836f\u7269\u5982\u7ef4\u751f\u7d20C\u3001\u753e\u65cf\u5316\u5408\u7269\u3001\u5de6\u65cb\u591a\u5df4\u7b49\u60c5\u51b5\u4e0b\u51fa\u73b0\u5185\u751f\u808c\u9150\u6e05\u9664\u7387\u589e\u9ad8\u3002<\/p>\n

PART06\uff1a\u53ef\u4ee5\u6d4b\u5b9a\uff0c\u4e5f\u53ef\u4ee5\u4f30\u7b97<\/p>\n

Ccr\u53ef\u4ee5\u901a\u8fc7\u6807\u51c624\u5c0f\u65f6\u7559\u5c3f\u8ba1\u7b97\u6cd5\u62164\u5c0f\u65f6\u7559\u5c3f\u6539\u826f\u6cd5\u8fdb\u884c\u5b9e\u9a8c\u5ba4\u6d4b\u5b9a\uff0c\u4ece\u800c\u5f97\u51fa\u8f83\u51c6\u786e\u7684\u6570\u503c\u3002<\/p>\n

\u8ba1\u7b97\u516c\u5f0f\u5982\u4e0b\uff1a<\/p>\n

\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0c\u4eba\u4f53\u8840\u6db2\u4e2d\u7684\u808c\u9150\u53ef\u901a\u8fc7\u5185\u6e90\u6027\u548c\u5916\u6e90\u6027\u4e24\u79cd\u9014\u5f84\u751f\u6210\uff0c\u5185\u6e90\u6027\u808c\u9150\uff08\u5185\u751f\u808c\u9150\uff09\u662f\u4f53\u5185\u808c\u8089\u7ec4\u7ec7\u4ee3\u8c22\u7684\u4ea7\u7269\uff0c\u5916\u6e90\u6027\u808c\u9150\u662f\u8089\u7c7b\u98df\u7269\u5728\u4f53\u5185\u4ee3\u8c22\u540e\u7684\u4ea7\u7269\u3002\u56e0\u6b64\uff0c\u4e3a\u4fdd\u6301\u8840\u808c\u9150\u6d53\u5ea6\u6052\u5b9a\uff0c\u5728\u68c0\u6d4b\u5185\u751f\u808c\u9150\u524d\u5e94\u7981\u98df\u8089\u7c7b\u98df\u7269\uff0c\u907f\u514d\u5267\u70c8\u8fd0\u52a8\u3002<\/p>\n

Ccr\u4e5f\u53ef\u4ee5\u901a\u8fc7\u5404\u79cd\u516c\u5f0f\u6765\u4f30\u7b97\uff0c\u4f46\u6709\u65f6Ccr\u5b9e\u6d4b\u503c\u548c\u4f30\u7b97\u6570\u503c\u5b58\u5728\u5dee\u5f02\u3002<\/p>\n

\u808c\u9150\u6e05\u9664\u7387\uff08CCR\uff09\u2014\u2014\u8ba1\u7b97\u65b9\u5f0f<\/p>\n

\u901a\u5e38\u7684\u808c\u9150\u6e05\u9664\u7387\uff08Ccr\uff09\u9700\u8ba1\u7b97\u516c\u5f0f\u5982\u4e0b\uff1a <\/p>\n

\u2605\u6807\u51c624h\u7559\u5c3f\u8ba1\u7b97\u6cd5\uff1a<\/p>\n

Ccr=\u5c3f\u808c\u9150\/\u8840\u808c\u9150\u00d724h\u5c3f\u91cf\uff08ml\uff09\u00d7\uff081.73\/A\uff09\uff08A\uff1a\u53d7\u8bd5\u8005\u5b9e\u6d4b\u4f53\u8868\u9762\u79efm2\uff09<\/p>\n

\u2605Cockcroft-Gault\u516c\u5f0f\uff08\u672a\u6821\u6b63\u4f53\u8868\u9762\u79ef\uff09\uff1a<\/p>\n

Ccr=\uff08140-\u5e74\u9f84\uff09\u00d7\u4f53\u91cd\uff08kg\uff09\/72\u00d7\u8840\u808c\u9150\uff08mg\/dl\uff09\u6216Ccr=[\uff08140-\u5e74\u9f84\uff09\u00d7\u4f53\u91cd\uff08kg\uff09]\/[0.818\u00d7\u8840\u808c\u9150\uff08umol\/L\uff09]\uff08\u5973\u6027\u6309\u8ba1\u7b97\u7ed3\u679c\u00d70.85\uff09\u3002<\/p>\n

\u2605Cockcroft-Gault\u516c\u5f0f\u5bf9\u8001\u5e74\u3001\u8d85\u91cd\u60a3\u8005\u51c6\u786e\u5ea6\u4e0d\u9ad8\uff0c\u56e0\u4e3a\u8fd9\u4e9b\u60a3\u8005\u672c\u8eab\u542b\u808c\u9178\u7684\u7269\u8d28\u6444\u5165\u91cf\u8fc7\u591a\uff0c\u6216\u808c\u8089\u7ec4\u7ec7\u7834\u574f\u589e\u52a0\uff0c\u8fd9\u4e9b\u56e0\u7d20\u53ef\u80fd\u9020\u6210\u4f53\u5185\u808c\u9150\u8fc7\u591a\u3002\u4f53\u91cd\u8d85\u8fc7\u7406\u60f3\u4f53\u91cd\u768420%\u6216BMI>30kg\/m2\u7528\u4e0b\u9762\u7684\u516c\u5f0f\u8ba1\u7b97\u808c\u9150\u6e05\u9664\u7387\uff1a<\/p>\n

\u808c\u9150\u6e05\u9664\u7387\uff08\u7537\uff09=\/\u301051\u00d7\u8840\u6e05\u808c\u9150\uff08mg\/dl\uff09\u3011<\/p>\n

\u808c\u9150\u6e05\u9664\u7387\uff08\u5973\uff09=\/\u301060\u00d7\u8840\u6e05\u808c\u9150\uff08mg\/dl\uff09\u3011<\/p>\n

\u8840\u808c\u9150\u503c\u53ef\u4ee5\u7528\u4e8e\u4f30\u7b97Ccr\uff0c\u90a3\u4e48\u5355\u7eaf\u7684\u8840\u808c\u9150\u503c\u662f\u5426\u53ef\u4ee5\u4f5c\u4e3a\u80be\u529f\u80fd\u7684\u8bc4\u4ef7\u6307\u6807\u5462\uff1f<\/p>\n

\u7b54\u6848\u662f\u80af\u5b9a\u7684\u3002\u5728\u5916\u6e90\u6027\u808c\u9150\u6444\u5165\u91cf\u7a33\u5b9a\u7684\u60c5\u51b5\u4e0b\uff0c\u8840\u6db2\u4e2d\u808c\u9150\u7684\u6d53\u5ea6\u53d6\u51b3\u4e8e\u80be\u5c0f\u7403\u7684\u6ee4\u8fc7\u80fd\u529b\uff0c\u56e0\u6b64\uff0c\u8840\u808c\u9150\u6d53\u5ea6\u7684\u5347\u9ad8\u89c1\u4e8e\u5404\u79cd\u539f\u56e0\u5f15\u8d77\u7684\u80be\u5c0f\u7403\u6ee4\u8fc7\u529f\u80fd\u51cf\u9000\u3002<\/p>\n

\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0c\u5f53\u80be\u5b9e\u8d28\u635f\u5bb3\u3001GFR\u964d\u4f4e\u5230\u4e34\u754c\u70b9\u540e\uff08GFR\u4e0b\u964d\u5230\u6b63\u5e38\u4eba\u76841\/3\u65f6\uff09\uff0c\u8840\u808c\u9150\u6d53\u5ea6\u624d\u4f1a\u660e\u663e\u4e0a\u5347\u3002\u6545\u6d4b\u5b9a\u8840\u808c\u9150\u7684\u6d53\u5ea6\uff0c\u53ef\u4f5c\u4e3aGFR\u53d7\u635f\u7684\u6307\u6807\uff0c\u4f46\u5176\u4e0d\u662f\u65e9\u671f\u80be\u529f\u80fd\u635f\u4f24\u7684\u8bca\u65ad\u6307\u6807\u3002\u4f46\u5728\u80be\u5c0f\u7403\u8f7b\u5ea6\u635f\u4f24\u65f6\uff0c\u8840\u6e05Cys C\u5373\u53ef\u51fa\u73b0\u660e\u663e\u6539\u53d8\uff0c\u6545\u65e9\u671f\u80be\u529f\u80fd\u76d1\u6d4b\u5e94\u53c2\u8003\u03b22-\u5fae\u7403\u86cb\u767d\u3001\u80f1\u6291\u7d20C\u3001\u03b11-\u5fae\u7403\u86cb\u767d\u3001\u89c6\u9ec4\u9187\u7ed3\u5408\u86cb\u767d\u3001\u8840\u5c3f\u7d20\u6c2e\u7b49\u6307\u6807\u3002<\/p>\n

GFR\u662f\u8bc4\u4f30\u80be\u5c0f\u7403\u6ee4\u8fc7\u529f\u80fd\u6700\u91cd\u8981\u7684\u53c2\u6570\uff0c\u4e34\u5e8a\u4e2d\u5e38\u7528Ccr\u6765\u8bc4\u4f30GFR\uff0c\u4f46\u4e24\u8005\u4ecd\u5b58\u5728\u4e00\u5b9a\u7684\u5dee\u5f02\u3002\u808c\u9150\u53ef\u4ee5\u5168\u90e8\u7531\u80be\u5c0f\u7403\u6ee4\u8fc7\uff0c\u4f46\u80be\u5c0f\u7ba1\u548c\u96c6\u5408\u7ba1\u65e2\u80fd\u5206\u6ccc\u4e5f\u53ef\u91cd\u5438\u6536\u5c11\u91cf\u7684\u808c\u9150\uff0c\u5e76\u4e14\u6d4b\u5b9aCcr\u65f6\u8fd8\u5e94\u907f\u514d\u5916\u6e90\u6027\u808c\u9150\u7684\u5f71\u54cd\uff0c\u56e0\u6b64\u7cbe\u786e\u7684GFR\u503c\u5e76\u4e0d\u80fd\u76f4\u63a5\u7528Ccr\u503c\u6765\u4ee3\u66ff\u3002\u6b64\u5916\uff0c\u5bf9\u4e8e\u80be\u810f\u75be\u75c5\u65e9\u671f\u8bca\u65ad\uff0c\u9700\u8981\u8054\u5408CYS-C\u3001\u03b22-\u5fae\u7403\u86cb\u767d\u3001\u5c3f\u5fae\u91cf\u767d\u86cb\u767d\u3001\u89c6\u9ec4\u9187\u7b49\u65e9\u671f\u6307\u6807\uff0c\u7efc\u5408\u5206\u6790\u3002\u8001\u8bdd\u7ee7\u7eed\u2014\u2014\u68c0\u4ee5\u6c42\u771f\uff0c\u9a8c\u4ee5\u6b63\u5fb7\uff01<\/p>\n","protected":false},"excerpt":{"rendered":"

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