{"id":51913,"date":"2025-05-20T05:11:03","date_gmt":"2025-05-20T05:11:03","guid":{"rendered":"http:\/\/zydq.1006ss.com\/?p=51913"},"modified":"2025-05-20T05:11:03","modified_gmt":"2025-05-20T05:11:03","slug":"%e7%bb%8f%e5%85%b8%e8%8d%af%e7%89%a9%e8%a5%bf%e5%9c%b0%e9%82%a3%e9%9d%9e%e5%92%8c%e6%9c%80%e6%96%b0%e6%ad%a6%e5%99%a8%e9%98%bf%e4%bc%90%e9%82%a3%e9%9d%9e%ef%bc%8c","status":"publish","type":"post","link":"http:\/\/zydq.1006ss.com\/?p=51913","title":{"rendered":"\u7ecf\u5178\u836f\u7269\u201c\u897f\u5730\u90a3\u975e\u201d\u548c\u6700\u65b0\u6b66\u5668\u201c\u963f\u4f10\u90a3\u975e\u201d\uff0c\u4e8c\u8005\u5982\u4f55\u9009\u62e9\uff1f"},"content":{"rendered":"

\u76ee\u524d\u968f\u7740\u73b0\u4ee3\u793e\u4f1a\u5feb\u901f\u8fdb\u6b65\uff0c\u751f\u6d3b\u8282\u594f\u6301\u7eed\u52a0\u5feb\uff0c\u7537\u6027\u9762\u4e34\u7684\u7ade\u4e89\u538b\u529b\u9010\u6e10\u589e\u5927\uff0c\u8eab\u5fc3\u5065\u5eb7\u72b6\u51b5\u9762\u4e34\u7740\u4e25\u5cfb\u7684\u6311\u6218\u3002\u636e\u300a2024\u5e74\u4e2d\u56fd\u6297ED\u836f\u7269\u884c\u4e1a\u767d\u76ae\u4e66\u300b\u663e\u793a\uff0c\u4e2d\u56fd40\u5c81\u4ee5\u4e0a\u7684\u7537\u6027ED\uff08\u52c3\u8d77\u529f\u80fd\u969c\u788d\uff09\u60a3\u75c5\u7387\u8d85\u8fc740%\uff0c\u4e14\u5448\u73b0\u968f\u5e74\u9f84\u589e\u957f\u800c\u9012\u589e\u7684\u8d8b\u52bf\u300260-69\u5c81\u4e3a48.4%\uff0c70\u5c81\u53ca\u4ee5\u4e0a\u4e3a81.6%\u3002\u8fd9\u4e00\u6570\u636e\u8868\u660e\uff0cED\u95ee\u9898\u5728\u4e2d\u5e74\u7537\u6027\u4e2d\u975e\u5e38\u666e\u904d\u3002<\/p>\n

\u9010\u5e74\u4e0a\u5347<\/p>\n

\u5c3d\u7ba1ED\u4e0d\u76f4\u63a5\u5a01\u80c1\u751f\u547d\uff0c\u4f46\u662f\u5bf9\u60a3\u8005\u53ca\u5176\u4f34\u4fa3\u7684\u6027\u751f\u6d3b\u8d28\u91cf\u3001\u7ef4\u62a4\u4eba\u9645\u5173\u7cfb\u4ee5\u53ca\u60c5\u7eea\u5065\u5eb7\u81f3\u5173\u91cd\u8981\uff0c\u800c\u4e14\u5bf9\u5a5a\u59fb\u5173\u7cfb\u7684\u7a33\u5b9a\u6709\u91cd\u8981\u5f71\u54cd\u3002<\/p>\n

\u4ece\u76f8\u5e94\u7684\u8c03\u67e5\u4e2d\u663e\u793a\uff0c\u5176\u5b9e\u793e\u4f1a\u751f\u6d3b\u4e2d\u5bf9ED\u60a3\u8005\u4ecd\u5b58\u5728\u9690\u5f62\u7684\u6b67\u89c6\uff0c\u76f8\u5173\u6570\u636e\u663e\u793a\uff0c\u670948.48%\u7684\u7537\u6027\u8ba4\u4e3a\u76ee\u524d\u793e\u4f1a\u5bf9ED\u7684\u8ba4\u77e5\u548c\u7406\u89e3\u662f\u8db3\u591f\u7684\uff0c\u8fd9\u4e3b\u8981\u5f97\u76ca\u4e8e\u77e5\u8bc6\u666e\u53ca\u529b\u5ea6\u7684\u589e\u52a0\u3001\u533b\u7597\u6280\u672f\u7684\u663e\u8457\u8fdb\u6b65\u4ee5\u53ca\u793e\u4f1a\u6587\u5316\u5305\u5bb9\u6027\u7684\u6301\u7eed\u63d0\u9ad8\u3002\u7136\u800c\uff0c\u4ecd\u6709\u8d85\u534a\u6570\u7684\u7537\u6027\u8ba4\u4e3a\u5f53\u524d\u793e\u4f1a\u5bf9ED\u7684\u63a5\u7eb3\u5ea6\u4e0d\u8db3\u3002\u90e8\u5206\u7fa4\u4f53\u53d7\u9650\u4e8e\u4fe1\u606f\u83b7\u53d6\u6e20\u9053\u7684\u8fc7\u5c11\u548c\u5065\u5eb7\u6559\u80b2\u7684\u7f3a\u5931\uff0c\u5bf9ED\u7684\u7406\u89e3\u4ecd\u505c\u7559\u5728\u521d\u7ea7\u9636\u6bb5\uff0c\u751a\u81f3\u5b58\u5728\u8bef\u89e3\u3002\u5e76\u4e14\u4f20\u7edf\u6027\u522b\u89d2\u8272\u671f\u5f85\u5f80\u5f80\u5c06\u7537\u6027\u80fd\u529b\u4e0e\u5176\u5c0a\u4e25\u7d27\u5bc6\u5173\u8054\uff0c\u90e8\u5206\u4eba\u7fa4\u4f1a\u5c06ED\u89c6\u4e3a\u4e2a\u4eba\u5f31\u70b9\uff0c\u793e\u4f1a\u5bf9ED\u60a3\u8005\u9690\u5f62\u7684\u6b67\u89c6\u73b0\u8c61\u4ecd\u7136\u5b58\u5728\uff0c\u4ece\u800c\u52a0\u5267\u60a3\u8005\u7684\u5fc3\u7406\u8d1f\u62c5\uff0c\u5bfc\u81f4\u5176\u4ea7\u751f\u4e25\u91cd\u7684\u75c5\u803b\u611f\u3002<\/p>\n

\u6240\u4ee5\uff0c\u5373\u4f7f\u5728\u4e34\u5e8a\u5df2\u7ecf\u8fd0\u7528\u5feb\u8d85\u8fc7\u4e09\u5341\u5e74\uff0c\u88ab\u8a89\u4e3a\u4e0a\u5e1d\u8d50\u7ed9\u4eba\u7c7b\u7684\u6700\u4f1f\u5927\u793c\u7269\u2014\u2014\u897f\u5730\u90a3\u975e\uff0c\u4e5f\u672a\u89c1\u8fd9\u90e8\u5206\u4eba\u4f7f\u7528\uff0c\u53cd\u800c\u53bb\u76f8\u4fe1\u548c\u8ff7\u604b\u5404\u79cd\u6240\u8c13\u7684\u504f\u65b9\uff0c\u6700\u7ec8\u5bfc\u81f4\u8eab\u4f53\u51fa\u73b0\u8fd9\u79cd\u6216\u8005\u90a3\u6837\u4e0d\u53ef\u633d\u6551\u7684\u635f\u5bb3\u3002<\/p>\n

\u897f\u5730\u90a3\u975e\u548c\u963f\u4f10\u90a3\u975e\u7684\u524d\u4e16\u4eca\u751f<\/h2>\n

\u8bf4\u8d77\u897f\u5730\u90a3\u975e\uff0c\u4e5f\u5c31\u662f\u5927\u540d\u9f0e\u9f0e\u7684\u201c\u5c0f\u84dd\u7247\u201d\uff0c\u4fd7\u79f0\u201c\u4f1f\u54e5\u201d\uff1b\u771f\u7684\u662f\u6709\u5fc3\u683d\u82b1\u82b1\u4e0d\u5f00\uff0c\u65e0\u5fc3\u63d2\u67f3\u67f3\u6210\u836b\uff0c\u5f53\u521d\u5b83\u7684\u95ee\u4e16\uff0c\u7eaf\u5c5e\u662f\u610f\u5916\uff0c\u5b83\u662f\u7531\u7f8e\u56fd\u8f89\u745e\u516c\u53f8\u7684\u5236\u836f\u5de5\u7a0b\u5e08David Brown\u57281998\u5e74\u53d1\u660e\u7684\uff0c\u5b83\u521d\u8877\u662f\u4e00\u79cd\u6cbb\u7597\u5fc3\u810f\u75c5\u7684\u65b0\u836f\uff0c\u53ef\u662f\u8be5\u836f\u5bf9\u6cbb\u7597\u5fc3\u810f\u75c5\u6cbb\u7597\u6548\u679c\u4e0d\u4f73\uff0c\u53cd\u800c\u4eba\u4f53\u8bd5\u9a8c\u7814\u7a76\u8fc7\u7a0b\u4e2d\u5374\u610f\u5916\u53d1\u73b0\uff0c\u5b83\u7684\u201c\u526f\u4f5c\u7528\u201d\u80fd\u8ba9\u7537\u6027\u5728\u623f\u4e8b\u8fc7\u7a0b\u4e2d\u8fc5\u901f\u8fdb\u5165\u72b6\u6001\u3002\u56e0\u6b64\uff0c\u516c\u53f8\u8c03\u6574\u8f6c\u53d8\u601d\u8def\uff0c\u5e72\u8106\u5c06\u836f\u7269\u8f6c\u5411\u4e13\u95e8\u5bf9\u6cbb\u7597\u52c3\u8d77\u529f\u80fd\u969c\u788d\uff08ED\uff09\u7684\u7814\u7a76\uff0c\u6700\u540e\u83b7\u5f97\u5de8\u5927\u7684\u6210\u529f\uff0c\u4f1f\u54e5\u4e5f\u88ab\u8a89\u4e3a\u201c\u4e8c\u5341\u4e16\u7eaa\u4e0a\u5e1d\u9001\u7ed9\u4eba\u7c7b\u6700\u597d\u7684\u793c\u7269\u201d\u3002<\/p>\n

\u897f\u5730\u90a3\u975e<\/p>\n

\u800c\u963f\u4f10\u90a3\u975e\uff0c\u76ee\u524d\u662f\u5c5e\u4e8e\u6cbb\u7597ED\u6700\u65b0\u4e00\u4ee3\u7684PDE5\u6291\u5236\u5242\uff0c\u57282021\u5e74\u4e4b\u524d\u5728\u56fd\u5185\u5c1a\u65e0\u751f\u4ea7\u548c\u8fdb\u53e3\u7684\u3002\u6700\u521d\u5b83\u662f\u7531\u65e5\u672c\u6a2a\u6ee8\u4e09\u83f1\u5236\u836f\u516c\u53f8\u57282000\u5e74\u5f00\u53d1\u7684\uff0c\u4f46\u9996\u5148\u4e0a\u5e02\u662f\u57282011\u5e741\u6708\uff0c\u5236\u836f\u5546JW\u4ee5\u5546\u54c1\u540dZepeed\u83b7\u97e9\u56fd\u98df\u54c1\u836f\u54c1\u7ba1\u7406\u5c40\uff08KFDA\uff09\u6279\u51c6\u4e0a\u5e02\u7684\uff0c2012\u5e744\u670827\u65e5\u7f8e\u56fd\u52a0\u5229\u798f\u5c3c\u4e9a\u7ef4\u798f\u65af\u5236\u836f\u516c\u53f8\u53d6\u5f97\u751f\u4ea7\u9500\u552e\u6743\u540e\uff0c\u5b83\u751f\u4ea7\u7684\u963f\u4f10\u90a3\u975e\uff08\u5546\u54c1\u540d\uff1aStendra\uff09\uff0c\u7ecf\u7f8e\u56fdFDA\u6279\u51c6\u5728\u7f8e\u56fd\u4e0a\u5e02\uff0c\u4e13\u95e8\u7528\u4e8e\u6cbb\u7597\u7537\u6027\u52c3\u8d77\u529f\u80fd\u969c\u788d\uff08ED\uff09\uff0c2013\u5e746\u670821\u65e5\u83b7\u5f97\u6b27\u6d32\u836f\u7269\u7ba1\u7406\u5c40\uff08EMA\uff09\u6279\u51c6\u4e0a\u5e02\u3002\u76ee\u524d\u5df2\u5728\u7f8e\u56fd\u3001\u5fb7\u56fd\u3001\u6cd5\u56fd\u3001\u610f\u5927\u5229\u7b49\u591a\u56fd\u4e0a\u5e02\u3002<\/p>\n

\u800c\u56fd\u5185\u662f\u57282021\u5e745\u670811\u65e5\uff0c\u4e0a\u6d77\u6c47\u4f26\u6c5f\u82cf\u836f\u4e1a\u6709\u9650\u516c\u53f8\u83b7\u5f97\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u6279\u51c6\u540e\uff0c\u4e8e\u540c\u5e74\u76846\u6708\u5728\u8d35\u9633\u53ec\u5f00\u7684\u5168\u56fd\u7537\u79d1\u5b66\u4f1a\u4e0a\u5ba3\u5e03\uff0c\u5176\u7814\u53d1\u7684\u4eff\u5236\u836f\u2014\u2014\u963f\u4f10\u90a3\u975e\uff08\u5546\u54c1\u540d\uff1a\u67ad\u96c4\uff09\u4e0a\u5e02\u3002\u540c\u5e74\u76849\u6708\uff0c\u6d77\u601d\u79d1\u836f\u96c6\u56e2\u4e5f\u5ba3\u5e03\u5176\u7814\u53d1\u7684\u4eff\u5236\u836f\u2014\u2014\u963f\u4f10\u90a3\u975e\uff08\u5546\u54c1\u540d\uff1a\u6d77\u9a70\uff09\u4e0a\u5e02\u3002\u81f3\u6b64\u624d\u586b\u8865\u4e86\u56fd\u5185\u963f\u4f10\u90a3\u975e\u5e02\u573a\u7684\u7a7a\u767d\u3002\u800c\u963f\u4f10\u90a3\u975e\u624d\u4e0a\u5e02\u534a\u5e74\u5de6\u53f3\uff0c\u5c31\u53d7\u5230\u4e86\u60a3\u8005\u5e7f\u5927\u7684\u6b22\u8fce\uff0c\u6709\u7740\u548c\u65e2\u5f80\u7ecf\u5178\u836f\u7269\u897f\u5730\u90a3\u975e\u4e00\u4e89\u9ad8\u4e0b\u7684\u8d8b\u52bf\u3002<\/p>\n

\u897f\u5730\u90a3\u975e\u548c\u963f\u4f10\u90a3\u975e\u7684\u533a\u522b<\/h2>\n

\u5176\u5b9e\u4e8c\u8005\u90fd\u662f\u5c5e\u4e8ePDE5\u6291\u5236\u5242\uff08\u4e2d\u6587\u540d\u79f0\uff1a5\u578b\u78f7\u9178\u4e8c\u916f\u9176\u6291\u5236\u5242\uff09\uff0c\u6cbb\u7597ED\u7684\u539f\u7406\u90fd\u5927\u81f4\u76f8\u540c\uff0c\u90fd\u662f\u963b\u6b62PDE5\u6c34\u89e3cGMP\uff08\u73af\u9e1f\u82f7\u9178\uff09\uff0c\u80fd\u8ba9\u6d77\u7ef5\u4f53\u5185\u7684cGMP\u8fd9\u79cd\u7269\u8d28\u6d53\u5ea6\u589e\u9ad8\uff0c\u5b58\u5728\u65f6\u95f4\u5ef6\u957f\uff0ccGMP\u7684\u6d53\u5ea6\u589e\u9ad8\u540e\uff0c\u53ef\u4f7f\u5f97\u6d77\u7ef5\u4f53\u8840\u7ba1\u5e73\u6ed1\u808c\u5904\u4e8e\u6269\u5f20\u72b6\u6001\uff0c\u5145\u8840\u4f9b\u8840\u589e\u52a0\uff0c\u4f7f\u5f97\u4e01\u4e01\u5145\u5206\u52c3\u8d77\u3002\u4f46\u662f\u7531\u4e8e\u5404\u81ea\u7684\u836f\u4ee3\u52a8\u529b\u5b66\u7279\u70b9\u4e0d\u540c\uff0c\u5728\u4e34\u5e8a\u836f\u6548\u4e0a\u662f\u4e0d\u4e00\u6837\u7684\u3002<\/p>\n

1\u3001\u4e8c\u8005\u8d77\u6548\u65f6\u95f4<\/p>\n

\u636e\u836f\u7269\u4ee3\u8c22\u52a8\u529b\u5b66\u4e0a\u663e\u793a\uff1a100mg\u963f\u4f10\u90a3\u975e\u53e3\u670d\u540e\uff0c15min\u4e2d\u5185\u5c31\u80fd\u8fbe\u5230\u6700\u5927\u8840\u836f\u6d53\u5ea6\uff08Tmax\uff09\u3002\u800c100mg\u897f\u5730\u90a3\u975e\u670d\u7528\u540e\uff0c30min-1h\u8d77\u6548\uff0c\u6700\u5927\u8840\u6d46\u6d53\u5ea6\u8fbe\u5cf0\u65f6\u95f4Tmax\u4e3a\uff1a0.8-1h\u3002\u7531\u6b64\u4e8c\u8005\u8d77\u6548\u65f6\u95f4\u5feb\u6162\u5982\u4e0b\uff1a<\/p>\n

\u836f\u7269<\/p>\n","protected":false},"excerpt":{"rendered":"

\u76ee\u524d\u968f\u7740\u73b0\u4ee3\u793e\u4f1a\u5feb\u901f\u8fdb\u6b65\uff0c\u751f\u6d3b\u8282\u594f\u6301\u7eed\u52a0\u5feb\uff0c\u7537\u6027\u9762\u4e34\u7684\u7ade\u4e89\u538b\u529b\u9010\u6e10\u589e\u5927\uff0c\u8eab\u5fc3\u5065\u5eb7 … \u7ee7\u7eed\u9605\u8bfb →<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[70],"tags":[],"class_list":["post-51913","post","type-post","status-publish","format-standard","hentry","category-70"],"_links":{"self":[{"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=\/wp\/v2\/posts\/51913","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=51913"}],"version-history":[{"count":0,"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=\/wp\/v2\/posts\/51913\/revisions"}],"wp:attachment":[{"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=51913"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=51913"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=51913"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}