\u7f16\u8005\u6309<\/p>\n
\u963f\u5c14\u8328\u6d77\u9ed8\u75c5(AD)\u662f\u4e00\u79cd\u8d77\u75c5\u9690\u533f\u7684\u8fdb\u884c\u6027\u53d1\u5c55\u7684\u795e\u7ecf\u7cfb\u7edf\u9000\u884c\u6027\u75be\u75c5\uff0c\u4e34\u5e8a\u4e0a\u4ee5\u8bb0\u5fc6\u51cf\u9000\u3001\u4eba\u683c\u548c\u884c\u4e3a\u969c\u788d\u3001\u8ba4\u77e5\u529f\u80fd\u548c\u7cbe\u795e\u969c\u788d\u7b49\u8868\u73b0\u4e3a\u7279\u5f81\uff0c\u5e76\u4f34\u6709\u795e\u7ecf\u708e\u6027\u6591\u5757\u548c\u795e\u7ecf\u539f\u7ea4\u7ef4\u7f20\u7ed3\u7684\u5178\u578b\u75c5\u7406\u5b66\u6539\u53d8\u3002<\/p>\n
\u76ee\u524d\u4e34\u5e8a\u4e2d\u4f7f\u7528\u8ba1\u7b97\u673a\u65ad\u5c42\u626b\u63cf\u548c\u78c1\u5171\u632f\u6210\u50cf\u7b49\u7ed3\u6784\u5f71\u50cf\u5b66\u6280\u672f\uff0c\u53ef\u4ee5\u7528\u4ee5\u8bca\u65ad\u8111\u7ec4\u7ec7\u7ed3\u6784\u6539\u53d8\u7684AD\u60a3\u8005\uff0c\u529f\u80fd\u5f71\u50cf\u5b66\u548c\u5206\u5b50\u5f71\u50cf\u5b66\u5206\u522b\u80fd\u4ece\u529f\u80fd\u6c34\u5e73\u548c\u5206\u5b50\u6c34\u5e73\u8bc4\u4f30AD\u7684\u53d1\u5c55\u8fdb\u7a0b\u548c\u53d8\u5316\u3002\u672c\u6587\u4ece\u5f71\u50cf\u5b66\u7684\u89d2\u5ea6\u6765\u8c08\u4e00\u8c08\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u7684\u8bca\u65ad\u4e0e\u9274\u522b\u8bca\u65ad\u3002<\/p>\n
\u4e00\u3001\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u7684\u53d1\u75c5\u673a\u5236<\/p>\n
\u963f\u5c14\u8328\u6d77\u9ed8\u75c5(AD)\u53c8\u79f0Alzheimer\u578b\u8001\u5e74\u6027\u75f4\u5446\uff0c\u662f\u5927\u8111\u76ae\u5c42\u7684\u4e00\u79cd\u53d8\u6027\u75c5\u3002\u76ee\u524d\u7684\u53d1\u75c5\u539f\u56e0\u4e0d\u660e\uff0c\u53d1\u75c5\u673a\u5236\u76ee\u524d\u6709\u4ee5\u4e0b\u4e00\u4e9b\u89c2\u70b9\uff1a<\/p>\n
1\u3001\u03b2\u6dc0\u7c89\u6837\u86cb\u767d(Amyloid protein,A\u03b2)\u6c89\u79ef\uff1aA\u03b2\u7531\u6dc0\u7c89\u6837\u524d\u4f53\u86cb\u767d(amyloid precursor protein,APP)\u65b9\u89e3\u4ea7\u751f\u3002\u6b63\u5e38\u60c5\u51b5\u4e0bA\u03b2\u7684\u4ea7\u751f\u548c\u964d\u89e3\u662f\u5e73\u8861\u7684\uff0c\u5f53\u51fa\u73b0APP\u57fa\u56e0\u7a81\u53d8\u6216\u8fc7\u8868\u8fbe\u7684\u7279\u6b8a\u72b6\u51b5\u4e0b\u5f15\u8d77A\u03b2\u5f02\u5e38\u6c89\u79ef\u5e76\u91ca\u653e\u795e\u7ecf\u6bd2\u6027\u4ea7\u7269\u5f15\u8d77\u795e\u7ecf\u7ec6\u80de\u7834\u574f\u3002<\/p>\n
2\u3001tau\u86cb\u767d\u4e0e\u795e\u7ecf\u5143\u7ea4\u7ef4\u7f20\u7ed3\uff1a\u5fae\u7ba1\u76f8\u5173\u86cb\u767d\u7684tau\u86cb\u767d\u53d1\u751f\u9ad8\u5ea6\u78f7\u9178\u5316\u3001\u5f02\u5e38\u7cd6\u57fa\u5316\u3001\u5f02\u5e38\u7cd6\u5316\u4ee5\u53ca\u6cdb\u7d20\u86cb\u767d\u5316\u65f6\uff0ctau\u86cb\u767d\u5931\u53bb\u5bf9\u7a33\u5b9a\u5fae\u7ba1\u7684\u675f\u7f1a\uff0c\u795e\u7ecf\u7ea4\u7ef4\u9000\u5316\uff0c\u4ea7\u751fAD\uff0c\u8fd9\u662fAD\u7684\u53e6\u4e00\u4e3b\u8981\u635f\u4f24\u56e0\u7d20\u3002<\/p>\n
3\u3001\u4e2d\u67a2\u795e\u7ecf\u9012\u8d28\u4ee3\u8c22\u969c\u788d\uff1a\u8fd9\u5176\u4e2d\u7684\u89c2\u70b9\u5305\u62ec\u80c6\u78b1\u80fd\u635f\u4f24\u5b66\u8bf4\u3001\u6c27\u5316\u5e94\u6fc0\u548c\u81ea\u7531\u57fa\u635f\u4f24\u8fd8\u6709\u5174\u594b\u6027\u6c28\u57fa\u9178\u6bd2\u6027\u4f5c\u7528\u7b49\u89c2\u70b9\u3002<\/p>\n
4\u3001\u9499\u4ee3\u8c22\u5e73\u8861\u5931\u8c03\uff1a\u7ec6\u80de\u4f4e\u9499\u5f71\u54cd\u7ec6\u80de\u7684\u901a\u900f\u6027\u8fd8\u53ef\u4f7f\u8840\u6e05\u8102\u8d28\u8fc7\u6c27\u5316(LPO)\u5347\u9ad8\uff0c\u81ea\u7531\u57fa\u751f\u6210\u589e\u52a0\uff0c\u4f7f\u795e\u7ecf\u7ec6\u80de\u53d1\u751f\u53d8\u6027\uff0c\u4ece\u800c\u4fc3\u8fdbAD\u7684\u53d1\u751f\u3002<\/p>\n
5\u3001\u57fa\u56e0\u7a81\u53d8\uff1a\u76ee\u524d\u5df2\u53d1\u73b05\u79cd\u57fa\u56e0\u7684\u7a81\u53d8\u6216\u591a\u578b\u4e0eAD\u6709\u5173\u3002\u8fd9\u4e9bAD\u76f8\u5173\u57fa\u56e0\u5305\u62ec\uff1a21\u53f7\u67d3\u8272\u4f53\u7684\u6dc0\u7c89\u6837\u86cb\u767d\u524d\u4f53(APP)\u57fa\u56e0\uff1b14\u53f7\u67d3\u8272\u4f53\u7684\u65e9\u8001\u86cb\u767d(PS)1\u57fa\u56e0\uff1b1\u53f7\u67d3\u8272\u4f53\u7684\u65e9\u8001\u86cb\u767d(PS)2\u57fa\u56e0\uff1b19\u53f7\u67d3\u8272\u4f53\u7684\u8f7d\u8102\u86cb\u767dE(ApoE4)\u57fa\u56e0\uff1b12\u53f7\u67d3\u8272\u4f53\u7684A2M\u57fa\u56e0\u3002<\/p>\n
\u5176\u4e2dPS1\u4e0eApoE4\u57fa\u56e0\u7f3a\u9677\u5728\u6563\u53d1\u6027AD\u4e2d\u8f83\u4e3a\u5e38\u89c1\uff0c\u8fd95\u79cdAD\u76f8\u5173\u57fa\u56e0\u4e2dAPP\u3001PS1\u3001PS2\u57fa\u56e0\u4e0e\u5bb6\u65cf\u6027\u65e9\u53d1\u578bAD\u6709\u5173\uff0c\u800cApoE\u57fa\u56e0\u53caA2M\u57fa\u56e0\u4e0e\u5bb6\u65cf\u6027\u8fdf\u53d1\u578bAD\u5173\u7cfb\u8f83\u5bc6\u5207\uff0c\u4e0e\u6563\u53d1\u6027AD\u4ea6\u6709\u4e00\u5b9a\u5173\u7cfb\u3002<\/p>\n
6\u3001\u5176\u4ed6\u89c2\u70b9\uff1a\u5185\u5206\u6ccc\u5931\u8c03\u5b66\u8bf4\u3001\u514d\u75ab\u3001\u708e\u75c7\u3001\u7ec6\u80de\u51cb\u4ea1\u7b49\u56e0\u7d20\u5728AD\u7684\u53d1\u75c5\u73af\u8282\u4e2d\u53d1\u6325\u4f5c\u7528\u3002<\/p>\n
\u4e8c\u3001\u4e34\u5e8a\u75c7\u72b6<\/p>\n
\u901a\u5e38\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u9690\u6027\u8d77\u75c5\uff0c\u5728\u51fa\u73b0\u5178\u578b\u75c7\u72b6\u524d20\u591a\u5e74\uff0c\u8111\u7ec4\u7ec7\u5c31\u53ef\u80fd\u53d1\u751f\u4e00\u7cfb\u5217\u7684\u75c5\u7406\u751f\u7406\u6539\u53d8\u3002\u4e4b\u540e A\u03b2 \u5f00\u59cb\u5728\u6954\u524d\u53f6\u548c\u5927\u8111\u76ae\u8d28\u533a\u57df\u9010\u6e10\u6c89\u79ef\uff0c\u60a3\u8005\u5f00\u59cb\u51fa\u73b0\u8fd9\u4e9b\u533a\u57df\u7684\u4f4e\u4ee3\u8c22\u3001tau\u75c5\u7406\u548c\u6d77\u9a6c\u4f53\u79ef\u7f29\u5c0f\u7b49\u75c7\u72b6\u3002<\/p>\n
\u5927\u591a\u6570\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u60a3\u8005 65\u5c81\u4ee5\u540e\u8d77\u75c5\u3002\u65e9\u671f\u5373\u51fa\u73b0\u8bb0\u5fc6\u969c\u788d\uff0c\u5c24\u5176\u662f\u8fd1\u8bb0\u5fc6\u969c\u788d\uff0c\u4e2d\u671f\u5931\u8bed\u3001\u5931\u7528\u3001\u5931\u8ba4\u53ca\u5176\u4ed6\u8ba4\u77e5\u7f3a\u635f\u540c\u65f6\u51fa\u73b0\uff0c\u665a\u671f\u53d1\u5c55\u4e3a\u667a\u80fd\u5168\u9762\u4e25\u91cd\u8870\u9000\uff0c\u5bf9\u5916\u754c\u523a\u6fc0\u65e0\u4efb\u4f55\u610f\u8bc6\u53cd\u5e94\u3002\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u76ee\u524d\u65e0\u6cd5\u6cbb\u6108\uff0c\u60a3\u8005\u591a\u5728\u75c5\u540e\u6570\u5e74\u6b7b\u4ea1\u3002<\/p>\n
1\u3001MRI\u4e34\u5e8a\u4e3b\u8981\u7279\u5f81<\/p>\n
\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u60a3\u8005MRI\u68c0\u67e5\u53ef\u663e\u793a\u5f25\u6f2b\u6027\u8111\u840e\u7f29\uff0c\u4ee5\u989e\u53f6\u5185\u4fa7\u548c\u6d77\u9a6c\u840e\u7f29\u6700\u660e\u663e\uff0c\u4fa7\u8111\u5ba4\u989e\u89d2\u6269\u5927\uff0c\u4e24\u4fa7\u591a\u4e0d\u5bf9\u79f0\uff0c\u665a\u671fAD\u5e7f\u6cdb\u7684\u76ae\u8d28\u840e\u7f29\u4e0e\u5176\u4ed6\u7c7b\u578b\u7684\u75f4\u5446\u665a\u671f\u65e0\u5dee\u522b\u3002<\/p>\n
\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u5e94\u7528MRI\u8fdb\u884c\u65e9\u671f\u8bca\u65ad\u65f6\uff0c\u80fd\u591f\u770b\u5230AD\u5f00\u59cb\u4e8e\u6d77\u9a6c\u548c\u989e\u53f6\u5185\u4fa7\uff0c\u6d77\u9a6c\u3001\u989e\u53f6\u840e\u7f29\u4e3a\u65e9\u671fAD\u8bca\u65ad\u7684\u53ef\u9760\u4f9d\u636e\u3002\u65e9\u8001\u671fAD(<65y)\u5f71\u50cf\u5b66\u663e\u793a\uff0c\u53ef\u80fd\u4f1a\u6709\u65f6\u8f7b\u5ea6\u6d77\u9a6c\u840e\u7f29\uff0c\u4f46\u6700\u4e3b\u8981\u7684\u8fd8\u662f\u4f34\u6709\u540e\u65b9\u6263\u5e26\u56de\u548c\u6954\u524d\u53f6\u840e\u7f29\u7684\u9876\u53f6\u840e\u7f29\uff0c\u6d77\u9a6c\u6709\u65f6\u4e5f\u53ef\u80fd\u662f\u6b63\u5e38\u7684(\u56fe1)\u3002<\/p>\n
\u56fe1.\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\uff1a\u60a3\u8005\uff0c\u5973\uff0c73\u5c81\uff0c\u8bb0\u5fc6\u529b\u4e0b\u964d\uff0c\u65f6\u800c\u795e\u5fd7\u604d\u60da\uff0c\u5b9a\u5411\u529b\u5dee\u3002\u5934\u9885MRI\u5e73\u626b\u6a2a\u65ad\u4f4dT1WI(A\u3001B)\u663e\u793a\u53cc\u4fa7\u8111\u6c9f\u3001\u8111\u6c60\u589e\u5bbd\uff0c\u8111\u56de\u840e\u7f29\uff0c\u53cc\u4fa7\u4fa7\u8111\u5ba4\u989e\u89d2\u589e\u5bbd\u3002\u51a0\u72b6\u4f4dT1WI(C)\u3001T2WI(D)\u548cFLAIR(E\u3001F)\u663e\u793a\u53cc\u4fa7\u989e\u53f6\u5185\u4fa7\u840e\u7f29\u660e\u663e\uff0c\u53cc\u4fa7\u6d77\u9a6c\u4f53\u79ef\u7f29\u5c0f\uff0c\u53cc\u4fa7\u4fa7\u8111\u5ba4\u989e\u89d2\u53ca\u8109\u7edc\u819c\u88c2\u589e\u5bbd\u8f83\u663e\u8457\u3002\u4e34\u5e8a\u968f\u8bbf\u8bc1\u5b9e\u4e3a\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u3002<\/p>\n
2\u3001CT\u4e34\u5e8a\u4e3b\u8981\u7279\u5f81<\/p>\n
\u5f71\u50cf\u5b66\u68c0\u67e5\u4e3b\u8981\u7528\u4e8e\u4e34\u5e8a\u8bca\u65ad\u4ee5\u53ca\u548c\u5176\u4ed6\u75be\u75c5\u7684\u9274\u522b\u8bca\u65ad\uff0c\u5982\u5728\u5bf9\u60a3\u8005\u8fdb\u884c\u91cf\u8868\u8bc4\u4f30\u540e\uff0c\u5f71\u50cf\u5b66\u68c0\u67e5\u53d1\u73b0\u989e\u53f6\u5185\u4fa7\u548c\u6d77\u9a6c\u840e\u7f29\u8f83\u660e\u663e\u65f6\u5219\u652f\u6301\u672c\u75c5\u7684\u8bca\u65ad\u3002CT\u68c0\u67e5\u53ef\u53d1\u73b0\u5f25\u6f2b\u6027\u8111\u76ae\u8d28\u840e\u7f29\uff0c\u6d77\u9a6c\u4f53\u79ef\u7f29\u5c0f(\u56fe2)\u3002<\/p>\n
\u56fe2. \u65e9\u8001\u671f\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\uff1a\u77e2\u72b6\u4f4d\u3001\u51a0\u72b6\u4f4dT1WI(A\u3001B)\u65e9\u8001\u671fAD\u60a3\u8005\u6b63\u5e38\u7684\u6d77\u9a6c\u548c\u9876\u53f6\u4e25\u91cd\u840e\u7f29<\/p>\n
\u56fe3. \u963f\u5c14\u8328\u6d77\u9ed8\u75c5\uff1aCT\u8f74\u4f4d\u53ca\u51a0\u72b6\u4f4d(A\u3001B)\u663e\u793a\u963f\u5c14\u8328\u6d77\u9ed8\u60a3\u8005\u53cc\u4fa7\u6d77\u9a6c\u4f53\u79ef\u7f29\u5c0f\uff0c\u8111\u8868\u9762\u8111\u6c9f\u589e\u5bbd\uff0c\u8111\u56de\u840e\u7f29<\/p>\n
\u4e09\u3001\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u7684\u9274\u522b\u8bca\u65ad<\/p>\n
\u5728\u4e34\u5e8a\u5f53\u4e2d\uff0cAD\u662f\u6700\u5e38\u89c1\u7684\u75f4\u5446\u7c7b\u578b\uff0c\u901a\u5e38\u4e0d\u53ef\u88ab\u6cbb\u6108\uff0c\u4f46\u6709\u65f6\u4e5f\u4f1a\u8bef\u8bca\u4e3a\u5176\u4ed6\u79d1\u5f15\u53d1\u8ba4\u77e5\u969c\u788d\u7684\u75be\u75c5\u3002\u56e0\u6b64\u5728\u5bf9\u60a3\u8005\u8fdb\u884c\u8bca\u65ad\u7684\u65f6\u5019\uff0c\u9700\u8981\u53ca\u65f6\u5bf9AD\u4e0e\u5176\u4ed6\u7c7b\u578b\u7684\u75f4\u5446\u8fdb\u884c\u9274\u522b\uff0cAD\u4e3b\u8981\u4e0e\u8840\u7ba1\u6027\u75f4\u5446(VD)\u3001\u989d\u989e\u53f6\u53d8\u6027\u3001\u76ae\u5c42\u4e0b\u52a8\u8109\u786c\u5316\u6027\u8111\u75c5\u3001\u6b63\u5e38\u538b\u529b\u6027\u8111\u79ef\u6c34\u7b49\u8fdb\u884c\u9274\u522b\u3002<\/p>\n
1\u3001\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u548c\u8840\u7ba1\u6027\u75f4\u5446\u7684\u9274\u522b<\/p>\n
\u5728\u6240\u6709\u75f4\u5446\u75be\u75c5\u4e2d\uff0c\u60a3\u75c5\u7387\u6700\u9ad8\u7684\u524d\u4e24\u4f4d\u75be\u75c5\u662fAD\u548c\u8840\u7ba1\u6027\u75f4\u5446(VD)\uff0c\u56e0\u6b64AD\u548cVD\u7684\u9274\u522b\u8bca\u65ad\u5c24\u4e3a\u91cd\u8981\u3002<\/p>\n
VD\u5927\u591a\u6570\u60a3\u8005\u4f34\u6709\u5e7f\u6cdb\u7684\u8111\u767d\u8d28\u75c5\u53d8(Fazekas 3)\uff0c\u8fd9\u4e9b\u60a3\u8005\u76ae\u8d28\u840e\u7f29\u5bfc\u81f4\u8111\u5ba4\u6269\u5927\uff0c\u6709\u4e9b\u60a3\u8005\u8fd8\u6709\u5185\u4fa7\u989e\u53f6\u7684\u840e\u7f29\uff0c\u4f46\u4ee5\u5c0f\u8840\u7ba1\u75c5\u53d8\u5bfc\u81f4\u7684\u76ae\u8d28\u840e\u7f29\u4e3a\u4e3b(\u56fe4)\u3002<\/p>\n
\u6709\u9ad8\u8840\u538b\u75c5\u53f2\u7684\u60a3\u8005\uff0c\u591a\u6570\u5728\u660e\u663e\u75f4\u5446\u524d\u6709\u8111\u8840\u7ba1\u76f8\u5173\u75c5\u53f2\uff0c\u75c5\u53d8\u90e8\u4f4d\u4e3b\u8981\u4f4d\u4e8e\u53cc\u4fa7\u57fa\u5e95\u8282\u533a\u3001\u4e18\u8111\u53ca\u4fa7\u8111\u5ba4\u65c1\uff0c\u8fd9\u4e9b\u533a\u57df\u4e0e\u4eba\u7684\u8ba4\u77e5\u529f\u80fd\u5173\u7cfb\u5bc6\u5207\uff0c\u5c24\u5176\u662f\u5185\u4fa7\u4e18\u8111\u6838\uff0c\u8be5\u533a\u57df\u53d1\u6325\u5b66\u4e60\u548c\u8bb0\u5fc6\u7684\u4e3b\u8981\u4f5c\u7528\uff0c\u5927\u7684\u5355\u4fa7\u6897\u6b7b\u6216\u53cc\u4fa7\u8111\u6897\u6b7b\u4f1a\u5bfc\u81f4\u75f4\u5446\u3002CT\u53caMRI\u53ef\u89c1\u591a\u5904\u76ae\u8d28\u3001\u76ae\u8d28\u4e0b\u548c\u767d\u8d28\u7684\u6897\u6b7b\u3001\u8154\u6897\u3001\u8111\u8f6f\u5316\u7076\u3001\u5e7f\u6cdb\u7684\u8111\u767d\u8d28\u75c5\u53d8\u3002<\/p>\n
MRI\u6d4b\u91cf\u6d77\u9a6c\u840e\u7f29\u53ef\u4f5c\u4e3a\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u8bca\u65ad\u4f9d\u636e\uff0cPET\u80fd\u654f\u611f\u5730\u53d1\u73b0\u65e9\u671fAD\u60a3\u8005\u3002FDG-PET\u53ef\u53d1\u73b0\u60a3\u8005\u6263\u5e26\u56de\u3001\u989e\u53f6\u3001\u9876\u53f6\u8461\u8404\u7cd6\u4ee3\u8c22\u8f83\u6b63\u5e38\u4eba\u51cf\u4f4e\uff0cSPECT\u53ef\u53d1\u73b0\u989e\u9876\u53f6\u8111\u8840\u6d41\u964d\u4f4e\u53ca\u4ee3\u8c22\u7387\u964d\u4f4e\uff0c\u53ef\u6709\u989d\u53f6\u7684\u8111\u8840\u6d41\u964d\u4f4e\u53ca\u4ee3\u8c22\u7387\u964d\u4f4e\u3002<\/p>\n
\u56fe4.\u8840\u7ba1\u6027\u75f4\u5446\uff1a\u6a2a\u65ad\u4f4d FLAIR\u3001\u51a0\u72b6\u4f4dT2WI(A\u3001B)\u663e\u793a\u8840\u7ba1\u6027\u75f4\u5446\u60a3\u8005\u4fa7\u8111\u5ba4\u5468\u56f4\u5927\u7247\u8111\u767d\u8d28\u75c5\u53d8(Fazekas 3\u7ea7)\uff0c\u540c\u65f6\u4f34\u6709\u8111\u5ba4\u6269\u5927<\/p>\n
2\u3001\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u548c\u989d\u989e\u53f6\u53d8\u6027\u7684\u9274\u522b<\/p>\n
\u989d\u989e\u53f6\u53d8\u6027(FTLD)\u6bd4AD\u5c11\u89c1\uff0cFTLD\u8111\u840e\u7f29\u4e3b\u8981\u5c40\u9650\u4e8e\u989d\u53f6\u548c(\u6216)\u989e\u53f6\uff0c\u53cc\u4fa7\u591a\u4e0d\u5bf9\u79f0\uff0c\u6700\u663e\u8457\u7684\u8868\u73b0\u662f\u4e0d\u5bf9\u79f0\u7684\u5de6\u4fa7\u989e\u53f6\u6781\u5ea6\u840e\u7f29\uff0c\u5728\u6a2a\u65ad\u4f4d\u8868\u73b0\u50cf\u5200\u7247\u6837\uff0c\u79f0\u4e3a\u201c\u5200\u7247\u72b6\u840e\u7f29\u201d(\u56fe5)\u5de6\u4fa7\u989e\u53f6\u840e\u7f29\u60a3\u8005\u5e38\u6709\u663e\u8457\u7684\u4e34\u5e8a\u75c7\u72b6\uff0c\u53f3\u4fa7\u840e\u7f29\u7684\u60a3\u8005\u75c7\u72b6\u5e38\u4e0d\u660e\u663e\u3002<\/p>\n
\u56fe5.\u989d\u989e\u53f6\u53d8\u6027\uff1a\u6a2a\u65ad\u4f4dFLAIR(A\u3001B)\u663e\u793a\u5de6\u4fa7\u989e\u53f6\u5200\u7247\u72b6\u840e\u7f29\uff0c\u53f3\u4fa7\u989e\u53f6\u6b63\u5e38<\/p>\n
3\u3001\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u548c\u76ae\u5c42\u4e0b\u52a8\u8109\u786c\u5316\u6027\u8111\u75c5\u7684\u9274\u522b<\/p>\n
\u76ae\u5c42\u4e0b\u52a8\u8109\u786c\u5316\u6027\u8111\u75c5\u53c8\u79f0Binswanger\u75c5\uff0c\u60a3\u8005\u5e38\u6709\u9ad8\u8840\u538b\u3002CT\u8868\u73b0\u4e3a\u8111\u5ba4\u5468\u56f4\u53ca\u534a\u5375\u5706\u533a\u5bf9\u79f0\u6027\u4f4e\u5bc6\u5ea6\u5f71\uff0c\u4ee5\u524d\u89d2\u5468\u56f4\u660e\u663e\uff0c\u767d\u8d28\u5bc6\u5ea6\u4f4e\u4e8e\u7070\u8d28\uff0c\u591a\u4f34\u6709\u8154\u9699\u6027\u8111\u6897\u6b7b\u53ca\u8111\u840e\u7f29\u5f81\u8c61\u3002MRI\u8868\u73b0\u4e3a\u53cc\u4fa7\u534a\u5375\u5706\u4e2d\u5fc3\u53ca\u4fa7\u8111\u5ba4\u65c1\u6df1\u90e8\u8111\u767d\u8d28\u957fT1\u3001\u957fT2\u4fe1\u53f7\uff0c\u5e38\u4f34\u6709\u8154\u9699\u6027\u8111\u6897\u6b7b\u53ca\u8111\u840e\u7f29\u8868\u73b0(\u56fe6)\u3002<\/p>\n
\u56fe6.\u76ae\u5c42\u4e0b\u52a8\u8109\u786c\u5316\u6027\u8111\u75c5\uff1a\u6a2a\u65ad\u4f4dT2WI(A\u3001B)\u663e\u793a\u53cc\u4fa7\u534a\u5375\u5706\u4e2d\u5fc3\u53ca\u4fa7\u8111\u5ba4\u65c1\u6591\u7247\u72b6\u957fT2\u4fe1\u53f7\u5f71\uff0c\u4fa7\u8111\u5ba4\u65c1\u89c1\u591a\u53d1\u6027\u8111\u8f6f\u5316\u7076\uff0c\u8111\u8868\u9762\u8111\u6c9f\u589e\u5bbd\u3001\u8111\u56de\u840e\u7f29\u56fe<\/p>\n
4\u3001\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u548c\u6b63\u5e38\u538b\u529b\u6027\u8111\u79ef\u6c34\u7684\u9274\u522b<\/p>\n
\u6b63\u5e38\u538b\u529b\u6027\u8111\u79ef\u6c34\u4e34\u5e8a\u4e0a\u6b63\u5e38\u538b\u529b\u6027\u8111\u79ef\u6c34\u4ee5\u75f4\u5446\u3001\u6b65\u6001\u4e0d\u7a33\u548c\u5c3f\u5931\u7981\u4e3a\u4e34\u5e8a\u4e09\u4e3b\u5f81\u7684\u7efc\u5408\u5f81\u3002\u8111\u810a\u6db2\u538b\u529b\u6b63\u5e38\uff0c\u800c\u8111\u810a\u6db2\u5206\u6d41\u80fd\u51cf\u8f7b\u75c7\u72b6\uff0c\u8fd9\u662f\u6b63\u5e38\u538b\u529b\u6027\u8111\u79ef\u6c34\u8bca\u65ad\u7684\u201c\u91d1\u6807\u51c6\u201d\u3002\u5f71\u50cf\u4e0a\uff0c\u6b63\u5e38\u538b\u529b\u6027\u8111\u79ef\u6c34\u4ee5\u8111\u5ba4\u6269\u5927\u663e\u8457\uff0c\u800c\u8111\u6c9f\u8111\u88c2\u6269\u5927\u8f83\u4e0d\u660e\u663e\uff0c\u6d77\u9a6c\u548c\u989e\u53f6\u5185\u4fa7\u5e38\u65e0\u660e\u663e\u840e\u7f29(\u56fe7)\u3002<\/p>\n
\u56fe7 .\u6b63\u5e38\u538b\u529b\u6027\u8111\u79ef\u6c34<\/p>\n
\u6a2a\u65ad\u4f4dFLAIR(A)\u3001T1WI(B)\u663e\u793a\u6b63\u5e38\u538b\u529b\u6027\u8111\u79ef\u6c34\u5927\u8111\u51f8\u9762\u8111\u6c9f\u548c\u86db\u7f51\u819c\u4e0b\u8154\u7a84\u5c0f\uff0c\u53cc\u4fa7\u4fa7\u8111\u5ba4\u6269\u5927\uff0c\u5e76\u53ef\u663e\u793a\u4fa7\u8111\u5ba4\u65c1\u95f4\u8d28\u6027\u6c34\u80bf\u3002<\/p>\n
\u53c2\u8003\u6587\u732e\uff1a<\/p>\n
[1]\u56fd\u5bb6\u536b\u751f\u5065\u5eb7\u59d4\u529e\u516c\u5385.\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u7684\u8bca\u7597\u89c4\u8303(2020\u5e74\u7248)[J].\u5168\u79d1\u533b\u5b66\u4e34\u5e8a\u4e0e\u6559\u80b2\uff0c2021\uff0c19(1):4-6. DOI\uff1a10.13558\/j.cnki.issn1672-3686.2021.001.002.<\/p>\n
[2]\u674e\u8054\u5fe0 \u5f20\u5ffb\u5b87.\u9885\u8111MRI\u8bca\u65ad\u4e0e\u9274\u522b\u8bca\u65ad[M]\u4eba\u6c11\u536b\u751f\u51fa\u7248\u793e,2014:306-310.<\/p>\n
\u7f16\u8f91 | \u6696\u6696<\/p>\n
\u6392\u7248 | \u6696\u6696<\/p>\n
\u5ba1\u6838 | \u91cc\u91cc<\/p>\n","protected":false},"excerpt":{"rendered":"
\u7f16\u8005\u6309 \u963f\u5c14\u8328\u6d77\u9ed8\u75c5(AD)\u662f\u4e00\u79cd\u8d77\u75c5\u9690\u533f\u7684\u8fdb\u884c\u6027\u53d1\u5c55\u7684\u795e\u7ecf\u7cfb\u7edf\u9000\u884c\u6027\u75be\u75c5\uff0c\u4e34\u5e8a … \u7ee7\u7eed\u9605\u8bfb