{"id":45403,"date":"2024-12-24T05:10:44","date_gmt":"2024-12-24T05:10:44","guid":{"rendered":"https:\/\/zydq.1006ss.com\/?p=45403"},"modified":"2024-12-24T05:10:44","modified_gmt":"2024-12-24T05:10:44","slug":"%e7%94%b2%e7%8a%b6%e8%85%ba%e6%9c%aa%e5%88%86%e5%8c%96%e7%99%8c-%e9%97%b4%e5%8f%98%e6%80%a7%e7%94%b2%e7%8a%b6%e8%85%ba%e7%99%8c%ef%bc%88atc%ef%bc%89","status":"publish","type":"post","link":"http:\/\/zydq.1006ss.com\/?p=45403","title":{"rendered":"\u7532\u72b6\u817a\u672a\u5206\u5316\u764c\/\u95f4\u53d8\u6027\u7532\u72b6\u817a\u764c\uff08ATC\uff09"},"content":{"rendered":"<\/p>\n<p>\u7532\u72b6\u817a\u672a\u5206\u5316\u764c<\/p>\n<p>\u2460\u53c8\u79f0\u95f4\u53d8\u6027\u7532\u72b6\u817a\u764c\uff08ATC\uff09\uff0c\u7ea6\u5360\u6240\u6709\u7532\u72b6\u817a\u764c\u76841-2%\uff0c\u901a\u5e38\u53d1\u751f\u4e8e60\u5c81\u4ee5\u540e\u3002<\/p>\n<p>\u2461\u9ad8\u5ea6\u6076\u6027\u3001\u975e\u5305\u819c\u6027\u4e14\u5e7f\u6cdb\u6269\u6563\uff0c\u76ae\u80a4\u3001\u808c\u8089\u3001\u795e\u7ecf\u3001\u8840\u7ba1\u3001\u5589\u548c\u98df\u7ba1\u7b49\u90bb\u8fd1\u7ed3\u6784\u6d78\u6da6\u7684\u8ff9\u8c61\u5f88\u5e38\u89c1\u3002<\/p>\n<p>\u24622022\u5e74WHO\u7532\u72b6\u817a\u9cde\u72b6\u7ec6\u80de\u764c\u88ab\u7eb3\u5165\u672a\u5206\u5316\uff08\u95f4\u53d8\u6027\uff09\u7532\u72b6\u817a\u764c\u3002<\/p>\n<p>\u4e34\u5e8a\uff1a<\/p>\n<p>\u9888\u90e8\u80bf\u5757\uff0c\u58f0\u97f3\u5636\u54d1\u548c\u547c\u5438\u3001\u541e\u54bd\u56f0\u96be\uff0c\u7ea630%\u5f15\u8d77\u58f0\u5e26\u9ebb\u75f9\u3002<\/p>\n<p>\u5927\u4f53\uff1a<\/p>\n<p>\u4f53\u79ef\u5927\uff0c\u5448\u878d\u5408\u72b6\uff0c\u5f80\u5f80\u6ca1\u6709\u5305\u819c\uff0c\u8fb9\u754c\u4e0d\u6e05\uff0c\u5927\u90e8\u5206\u7532\u72b6\u817a\u5df2\u88ab\u9ad8\u5ea6\u51fa\u8840\u548c\u574f\u6b7b\u7684\u5b9e\u6027\u80bf\u7624\u53d6\u4ee3\uff0c\u53ef\u80fd\u5bfc\u81f4\u7532\u72b6\u817a\u5448\u5f25\u6f2b\u6027\u80bf\u5927\uff0c\u5e38\u5e38\u53d1\u73b0\u65f6\u5373\u5df2\u665a\u671f\u3002<\/p>\n<p>\u955c\u4e0b\u7ec4\u7ec7\u5b66\u5f62\u6001\uff1a<\/p>\n<p>\u4e00\u3001\u9cde\u72b6\u7ec6\u80de\u6837\uff08\u4e0a\u76ae\u6837\u578b\uff0c\u53ef\u4ee5\u6df7\u6709\u660e\u786e\u7684\u89d2\u5316\u7076\uff09<\/p>\n<p>\u2460\u4f34\u6216\u4e0d\u4f34\u5206\u5316\u578b\u7532\u72b6\u817a\u764c\u6210\u5206\u7684\u9cde\u72b6\u7ec6\u80de\u764c\uff0c\u5927\u591a\u8868\u73b0\u51faBRAF V600E\u7a81\u53d8\uff08\u540c\u4e00\u822c\u7684\u95f4\u53d8\u6027\u7532\u72b6\u817a\u764c\uff0c\u9884\u540e\u4e5f\u76f8\u540c\uff09\u3002<\/p>\n<p>\u2461\u6ee4\u6ce1\u7ec6\u80de\u6765\u6e90\uff08\u53ef\u8868\u8fbe\u8868\u8fbePAX8\u548cTTF1\uff0c91%\u300138%\uff09<\/p>\n<p>\u2462\u591a\u6570\u75c5\u4f8b\u4f34\u5206\u5316\u578b\u7532\u72b6\u817a\u764c\u3002<\/p>\n<p>\u4e8c\u3001\u8089\u7624\u6837<\/p>\n<p>\u2460\u68ad\u5f62\u7ec6\u80de\u578b<\/p>\n<p>\u675f\u72b6\u6216\u5e2d\u7eb9\u72b6\u751f\u957f\u65b9\u5f0f\uff0c\u91cd\u5ea6\u7684\u2606\u4e2d\u6027\u7c92\u7ec6\u80de\u6d78\u6da6\uff0c\u660e\u663e\u7684\u8840\u7ba1\u5f62\u6210\uff0c\u4ee5\u53ca\u4e0d\u540c\u7a0b\u5ea6\u7684\u9aa8\u3001\u8f6f\u9aa8\u548c\u9aa8\u9abc\u808c\u5206\u5316\u3002\u4e0e\u9ad8\u7ea7\u522b\u591a\u5f62\u6027\u8089\u7624\u76f8\u4f3c\u3002<\/p>\n<\/p>\n<p>\u2461\u5de8\u7ec6\u80de\u578b\uff08\u6bd4\u68ad\u5f62\u548c\u9cde\u5316\u6837\u578b\u66f4\u660e\u663e\u7684\u591a\u5f62\u6027\uff09<\/p>\n<p>\u7531\u9ad8\u5ea6\u591a\u5f62\u6027\u7684\u80bf\u7624\u7ec6\u80de\u7ec4\u6210\uff0c\u53ef\u89c1\u2606\u7834\u9aa8\u7ec6\u80de\u6837\u591a\u6838\u7624\u5de8\u7ec6\u80de\uff08\u53ef\u4f7f\u80bf\u7624\u5f62\u6001\u7c7b\u4f3c\u4e8e\u9aa8\u6216\u8f6f\u7ec4\u7ec7\u7684\u5de8\u7ec6\u80de\u7624\uff09<\/p>\n<p>\u8fd9\u4e9b\u7834\u9aa8\u7ec6\u80de\u6837\u5de8\u7ec6\u80de\u53ef\u80fd\u5e76\u4e0d\u662f\u80bf\u7624\u7ec6\u80de\uff0c\u800c\u662f\u5355\u6838\/\u7ec4\u7ec7\u7ec6\u80de\u8c31\u7cfb\u5206\u5316\u7684\u53cd\u5e94\u6027\u7ec6\u80de\uff0c\u7531\u5355\u6838\u7ec6\u80de\u901a\u8fc7\u7ec6\u80de\u878d\u5408\u5f62\u6210\u3002<\/p>\n<p>\u2462\u5be1\u7ec6\u80de\u578b\uff08\u68ad\u5f62\u7ec6\u80de\u578b\u672a\u5206\u5316\u764c\u7684\u4e00\u79cd\u53d8\u5f02\u578b\uff09<\/p>\n<p>\u6709\u9ad8\u5ea6\u7684\u7ea4\u7ef4\u5316\u548c\u73bb\u7483\u6837\u53d8\u95f4\u8d28\uff0c\u7c7b\u4f3c\u4e8e\u6728\u6837\u7532\u72b6\u817a\u708e\uff0c\u53ef\u4ee5\u901a\u8fc7\u6563\u5728\u7684\u975e\u5178\u578b\u6027\u7ec6\u80de\u3001\u574f\u6b7b\u533a\u57df\u3001\u8840\u7ba1\u4fb5\u72af\u3001\u8840\u7ba1\u6e17\u5165\u4ee5\u53ca\u4e0a\u76ae\u6807\u5fd7\u7269\u8868\u8fbe\u6765\u8bc6\u522b\u3002<\/p>\n<\/p>\n<p>\u2463\u6a2a\u7eb9\u808c\u6837\u578b\uff08\u53ef\u4f5c\u4e3a\u5de8\u7ec6\u80de\u578b\u672a\u5206\u5316\u764c\u7684\u4e00\u4e2a\u53d8\u5f02\u578b\uff09<\/p>\n<p>\u80bf\u7624\u7ec6\u80de\u5448\u6a2a\u7eb9\u808c\u7ec6\u80de\u6837\u5f62\u6001<\/p>\n<p>\u2606\u80bf\u7624\u7ec6\u80de\u574f\u6b7b\uff1a\u5176\u8fb9\u7f18\u80bf\u7624\u7ec6\u80de\u5448\u6805\u680f\u72b6\u6392\u5217\uff0c\u4e14\u6613\u4e8e\u4fb5\u72af\u9759\u8109\u58c1\u5e76\u53d6\u4ee3\u6b63\u5e38\u7684\u7ba1\u58c1\u5e73\u6ed1\u808c\u3002<\/p>\n<\/p>\n<p>\u514d\u75ab\u7ec4\u5316\uff1a<\/p>\n<p>\u2460\u4e0a\u76ae\u6027\u8d28\uff1apCK\u5448\u9633\u6027\uff0cCK\u9634\u6027\u5e76\u4e0d\u80fd\u6392\u9664\u95f4\u53d8\u6027\u764c\u7684\u8bca\u65ad\u3002<\/p>\n<p>\u2461Vimentin\u6709\u7a33\u5b9a\u7684\u9633\u6027\u8868\u8fbe\uff08\u5c24\u5176\u5728\u68ad\u5f62\u7ec6\u80de\u578b\uff09\u3002<\/p>\n<p>\u2462\u7532\u72b6\u817a\u7403\u86cb\u767d\uff08TG\uff09\u51e0\u4e4e\u603b\u662f\u5448\u9634\u6027\uff0c\u5c24\u5176\u5728\u672a\u5206\u5316\u533a\u57df\uff08\u9633\u6027\u53ef\u80fd\u662f\u6b63\u5e38\u7532\u72b6\u817a\u7684\u5185\u9677\u548c\u6709\u5206\u5316\u8f83\u597d\u7684\u80bf\u7624\u6b8b\u7559\uff09\u3002<\/p>\n<p>\u2463PAX-8\u901a\u5e38\u4fdd\u7559\u3002\u5934\u9888\u90e8\u548c\u80ba\u90e8\u9cde\u72b6\u7ec6\u80de\u764c\u4e2d\u662f\u5448\u9634\u6027\u3002<\/p>\n<p>\u2464p53\u5448\u7a81\u53d8\u578b\u3002<\/p>\n<p>\u2465\u6709\u5f88\u9ad8\u7684\u589e\u6b96\u6d3b\u6027\uff0cKi67\uff1e30%\u3002<\/p>\n<\/p>\n<p>\u5206\u5b50\u673a\u5236\uff1a<\/p>\n<p>\u2460BRAF\u7a81\u53d8\uff08\u4e3b\u8981\u53d1\u73b0\u4e8e\u4f34\u4e73\u5934\u72b6\u6210\u5206\uff09<\/p>\n<p>\u2461RAS\u7a81\u53d8\uff08\u4e3b\u8981\u4e0e\u6ee4\u6ce1\u72b6\u751f\u957f\u7684\u80bf\u7624\u76f8\u5173\uff0c\u6ee4\u6ce1\u6027\u764c\u3001\u6ee4\u6ce1\u4e9a\u578b\u4e73\u5934\u72b6\u764c\u7b49\uff09<\/p>\n<p>\u2462TP53\u57fa\u56e0\u7a81\u53d8<\/p>\n<p>\u9884\u540e\uff1a<\/p>\n<p>\u6613\u53d1\u751f\u65e9\u671f\u8f6c\u79fb\uff0c\u4e2d\u4f4d\u751f\u5b58\u671f\u4ec5\u4e3a5\u4e2a\u6708\uff0c1\u5e74\u5b58\u6d3b\u7387\u4f4e\u4e8e20%\uff0c\u5728\u6240\u6709\u7532\u72b6\u817a\u80bf\u7624\u4e2d\u9884\u540e\u6700\u5dee\uff0c\u6b7b\u4ea1\u7684\u76f4\u63a5\u539f\u56e0\u901a\u5e38\u662f\u9888\u90e8\u7684\u91cd\u8981\u7ed3\u6784\u53d7\u7d2f\u3002<\/p>\n<p>\u58f0\u660e\uff1a\u4ee5\u4e0a\u77e5\u8bc6\u70b9\u53ca\u56fe\u7247\u6765\u6e90\u4e8e\u75c5\u7406\u76f8\u5173\u4e66\u7c4d\u53ca\u7f51\u7edc\uff0c\u4ec5\u7528\u4e8e\u4e2a\u4eba\u5b66\u4e60\u8bb0\u5f55\uff0c\u4fb5\u6743\u5220\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u7532\u72b6\u817a\u672a\u5206\u5316\u764c \u2460\u53c8\u79f0\u95f4\u53d8\u6027\u7532\u72b6\u817a\u764c\uff08ATC\uff09\uff0c\u7ea6\u5360\u6240\u6709\u7532\u72b6\u817a\u764c\u76841-2%\uff0c\u901a\u5e38 &hellip; <a href=\"http:\/\/zydq.1006ss.com\/?p=45403\">\u7ee7\u7eed\u9605\u8bfb <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[70],"tags":[],"class_list":["post-45403","post","type-post","status-publish","format-standard","hentry","category-70"],"_links":{"self":[{"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=\/wp\/v2\/posts\/45403","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=45403"}],"version-history":[{"count":0,"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=\/wp\/v2\/posts\/45403\/revisions"}],"wp:attachment":[{"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=45403"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=45403"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=45403"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}