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2. \u6784\u6548\u5173\u7cfb&nbsp;&nbsp;&nbsp; \u5429\u567b\u55ea\u7c7b\u836f\u7269\u4e3b\u8981\u662f\u4e0e\u591a\u5df4\u80fa\u53d7\u4f53\u7ed3\u5408\uff0c\u963b\u65ad\u591a\u5df4\u80fa\u4e0e\u53d7\u4f53\u7684\u7ed3\u5408\uff0c\u4ece\u800c\u53d1\u6325\u836f\u6548\u30021964\u5e74\uff0cGordon\u7b49\u7528\u836f\u7269\u4e0e\u53d7\u4f53\u95f4\u7684\u201c\u4e09\u70b9\u4e92\u9002\u5e94\u201d\u5b66\u8bf4\u6765\u52a0\u4ee5\u8bf4\u660e\u3002\u4ed6\u8ba4\u4e3a\uff0c\u5429\u567b\u55ea\u7c7b\u836f\u7269\u4e0e\u53d7\u4f53\u4e4b\u95f4\u7684\u76f8\u4e92\u4f5c\u7528\u6709A\u3001B\u3001C\u4e09\u4e2a\u90e8\u5206\u3002<\/p>\n<\/p>\n<p>&nbsp;&nbsp;&nbsp; 1 \u7acb\u4f53\u4e13\u5c5e\u6027\uff1aB&gt;C&gt;A&nbsp;&nbsp;&nbsp; 2 B\u533a&nbsp;&nbsp;&nbsp; 1\uff09\u7531\u6210\u76f4\u94fe\u7684\u4e09\u4e2a\u78b3\u7ec4\u6210\u662f\u5fc5\u987b\u7684\u3002&nbsp;&nbsp;&nbsp; \u82e5\u5c06\u4e09\u4e2aC\u539f\u5b50\u7684\u94fe\u7f29\u77ed\u62102\u4e2aC\u539f\u5b50\uff0c\u5219\u6297\u7cbe\u75c5\u6d3b\u6027\u4e0b\u964d\uff0c\u800c\u6297\u7ec4\u80fa\u4f5c\u7528\u52a0\u5f3a\u3002&nbsp;&nbsp;&nbsp; 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4 A\u533a&nbsp;&nbsp;&nbsp; \u57fa\u56e2\u5927\u6d3b\u6027\u4e0b\u964d\uff0c\u57fa\u56e2\u72ed\u7a84\u6d3b\u6027\u589e\u52a0\u3002&nbsp;&nbsp;&nbsp; 5 C2-Cl\u53d6\u4ee3\uff0c\u5206\u5b50\u5bf9\u79f0\u6027\uff0c\u4fa7\u94fe\u540cC-Cl\u540c\u4fa7\u4e3aZ\u578b\u987a\u5f0f\uff0c\u53cd\u4e4b\u4e3a\u53cd\u5f0f\u3002\u987a\u5f0f&gt;\u53cd\u5f0f&nbsp;&nbsp;&nbsp; 3. \u4ee3\u8868\u836f\u7269&nbsp;&nbsp;&nbsp; \u76d0\u9178\u6c2f\u4e19\u55ea&nbsp;&nbsp;&nbsp; 1 \uff09\u547d\u540d\u53ca\u7acb\u4f53\u5316\u5b66\u7ed3\u6784<\/p>\n<\/p>\n<p>&nbsp;&nbsp;&nbsp; N,N-\u4e8c\u7532\u57fa-2-\u6c2f-10H-\u5429\u567b\u55ea-10-\u4e19\u80fa\u76d0\u9178\u76d0&nbsp;&nbsp;&nbsp; (2-chloro-N,N- dimethyl-10H-phenothiazine-10-propanamine hydrochloride)&nbsp;&nbsp;&nbsp; 2\uff09 \u7ed3\u6784\u7279\u70b9&nbsp;&nbsp;&nbsp; \u6bcd\u73af\u4e3a\u5429\u567b\u55ea\u7684\u57fa\u672c\u7ed3\u6784&nbsp;&nbsp;&nbsp; \u4e09\u73af\u7ed3\u6784&nbsp;&nbsp;&nbsp; \u4e24\u4e2a\u82ef\u73af\uff0c\u8054\u7ed3\u4e00\u4e2a\u542b\u786b\u548c\u6c2e\u539f\u5b50\u7684\u73af\uff08\u567b\u55ea\u73af\uff09&nbsp;&nbsp;&nbsp; 3\uff09\u5316\u5b66\u6027\u8d28&nbsp;&nbsp;&nbsp; \u5429\u567b\u55ea\u6bcd\u73af\u6613\u88ab\u6c27\u5316\uff0c\u6c2f\u4e19\u55ea\u5728\u7a7a\u6c14\u6216\u65e5\u5149\u4e2d\u653e\u7f6e\u6e10\u53d8\u7ea2\u8272\u3002\u4e3a\u9632\u6b62\u53d8\u8272\uff0c\u5176\u6ce8\u5c04\u6db2\u5728\u751f\u4ea7\u4e2d\u53ef\u52a0\u5165\u5bf9\u6c22\u918c\u3001\u8fde\u4e8c\u4e9a\u786b\u9178\u94a0\u3001\u4e9a\u786b\u9178\u6c22\u94a0\u6216\u7ef4\u751f\u7d20C\u7b49\u6297\u6c27\u5242\u3002&nbsp;&nbsp;&nbsp; \u6c2f\u4e19\u55ea\u5728\u9047\u785d\u9178\u540e\u53ef\u80fd\u5f62\u6210\u81ea\u7531\u57fa\u6216\u918c\u5f0f\u7ed3\u6784\u800c\u663e\u7ea2\u8272\uff0c\u8fd9\u662f\u5429\u567b\u55ea\u7c7b\u5316\u5408\u7269\u7684\u5171\u6709\u53cd\u5e94\uff0c\u73b0\u7528\u4e8e\u9274\u522b\u3002<\/p>\n<\/p>\n<p>&nbsp;&nbsp;&nbsp; \u6709\u90e8\u5206\u75c5\u4eba\u7528\u836f\u540e\uff0c\u5728\u5f3a\u70c8\u65e5\u5149\u7167\u5c04\u4e0b\u53d1\u751f\u4e25\u91cd\u7684\u5149\u5316\u6bd2\u53cd\u5e94\u3002<\/p>\n<\/p>\n<p>&nbsp;&nbsp;&nbsp; 4\uff09\u5408\u6210\u8def\u7ebf&nbsp;&nbsp;&nbsp; \u4ee5\u90bb\u6c2f\u82ef\u7532\u9178\u548c\u95f4\u6c2f\u82ef\u80fa\u4e3a\u539f\u6599\uff0c\u8fdb\u884cullmann\u53cd\u5e94\uff0c\u5728\u9ad8\u6e29\u8131\u7fa7\u540e\uff0c\u4e0e\u786b\u7194\u878d\uff0c\u73af\u5408\u62102-\u6c2f-\u5429\u567b\u55ea\u6bcd\u73af\uff0c\u518d\u4e0eN\uff0cN-\u4e8c\u7532\u57fa-3-\u6c2f\u4e19\u80fa\u7f29\u5408\uff0c\u751f\u6210\u6c2f\u4e19\u55ea\uff0c\u6700\u540e\u6210\u76d0\u9178\u76d0\u3002<\/p>\n<\/p>\n<p>&nbsp;&nbsp;&nbsp; 5\uff09\u7a33\u5b9a\u6027&nbsp;&nbsp;&nbsp; \u5429\u567b\u55ea\u7c7b\u836f\u7269\u5206\u5b50\u4e2d\u542b\u6709\u5429\u567b\u55ea\u73af\uff0c\u6613\u6c27\u5316\uff0c\u5728\u7a7a\u6c14\u6216\u65e5\u5149\u4e2d\u653e\u7f6e\u6e10\u53d8\u4e3a\u7ea2\u68d5\u8272\u3002\u65e5\u5149\u53ca\u91cd\u91d1\u5c5e\u79bb\u5b50\u6709\u50ac\u5316\u4f5c\u7528\u3002\u9047\u6c27\u5316\u5242\u5219\u88ab\u7834\u574f\u3002&nbsp;&nbsp;&nbsp; 6\uff09 \u4f53\u5185\u4ee3\u8c22&nbsp;&nbsp;&nbsp; \u6c2f\u4e19\u55ea\u5728\u809d\u810f\u7ecf\u5fae\u7c92\u4f53\u836f\u7269\u4ee3\u8c22\u9176\u6c27\u5316\uff0c\u4f53\u5185\u4ee3\u8c22\u6781\u590d\u6742 \uff0c\u5728\u5c3f\u4e2d\u5b58\u572820\u591a\u79cd\u4ee3\u8c22\u7269&nbsp;&nbsp;&nbsp; \u53ef\u68c0\u6d4b\u7684\u4ee3\u8c22\u7269\u6709100\u591a\u79cd \uff0c\u786b\u539f\u5b50\u6c27\u5316\uff0c\u82ef\u6838\u7f9f\u5316\uff0c\u4fa7\u94fe\u53bbN-\u7532\u57fa\u548c\u4fa7\u94fe\u7684\u6c27\u5316\u7b49\u3002<\/p>\n<\/p>\n<p>&nbsp;&nbsp;&nbsp; 7\uff09 \u4f53\u5185\u4ee3\u8c22&nbsp;&nbsp;&nbsp; \u5177\u6709\u591a\u65b9\u9762\u7684\u836f\u7406\u4f5c\u7528\uff0c\u5b89\u5b9a\u4f5c\u7528\u8f83\u5f3a\u6cbb\u7597\u7cbe\u795e\u5206\u88c2\u75c7\u548c\u72c2\u8e81\u75c7\uff0c\u4ea6\u7528\u4e8e\u9547\u5410\u3001\u5f3a\u5316\u9ebb\u9189\u53ca\u4eba\u5de5\u51ac\u7720\u7b49\u3002&nbsp;&nbsp;&nbsp; 4. \u6c1f\u54cc\u5576\u9187&nbsp;&nbsp;&nbsp; 1\uff09 \u547d\u540d<\/p>\n<p>1-(4-\u6c1f\u82ef\u57fa)-4-[4-(4-\u6c2f\u82ef\u57fa)-4-\u7f9f\u57fa-1-\u54cc\u55ea\u57fa]-1-\u4e01\u916e(4-[4-(4- chlorophenyl)-4-hydroxy-1-piperidinyl]-1-(4-fluorophenyl)-1-butanone)<\/p>\n<p>&nbsp;&nbsp;&nbsp; 2\uff09 \u4f53\u5185\u4ee3\u8c22&nbsp;&nbsp;&nbsp; \u53e3\u670d\u540e\uff0c\u5728\u80c3\u80a0\u9053\u5438\u6536\u8f83\u597d\uff0c\u5728\u809d\u810f\u4ee3\u8c22\uff0c\u80be\u810f\u6d88\u9664\uff0c\u6709\u9996\u8fc7\u6548\u5e94\u3002\u4ee3\u8c22\u4ee5\u6c27\u5316\u6027N-\u8131\u70f7\u57fa\u53cd\u5e94\u548c\u916e\u57fa\u7684\u8fd8\u539f\u53cd\u5e94\u4e3a\u4e3b\u3002&nbsp;&nbsp;&nbsp; 3\uff09\u5408\u6210\u8def\u7ebf&nbsp;&nbsp;&nbsp; \u5408\u6210\u4ee5\u5bf9\u6c1f-\u03b3-\u6c2f\u4ee3\u4e01\u9170\u82ef\u4e3a\u539f\u6599\uff0c\u4e0e4-(4-\u6c2f\u82ef\u57fa)-4-\u54cc\u5576\u9187\u5728\u7898\u5316\u94be\u7684\u5b58\u5728\u4e0b\u52a0\u70ed\u7f29\u5408\u5236\u5f97\u3002<\/p>\n<\/p>\n<p>&nbsp;&nbsp;&nbsp; 4\uff09 \u6784\u6548\u5173\u7cfb<\/p>\n<\/p>\n<p>&nbsp;&nbsp;&nbsp; \u5c0f\u7ed3\uff1a&nbsp;&nbsp;&nbsp; 1\uff09\u6c2f\u6c2e\u5e73\u7684\u7ed3\u6784\u7279\u70b9\u53ca\u4e34\u5e8a\u7528\u9014\uff1b\u6297\u7cbe\u795e\u75c5\u836f\u7269\u7684\u4f5c\u7528\u673a\u5236\u3002&nbsp;&nbsp;&nbsp; 2\uff09\u6297\u7cbe\u795e\u5931\u5e38\u836f\u7684\u7ed3\u6784\u7c7b\u578b\u3002&nbsp;&nbsp;&nbsp; 3\uff09\u6c2f\u4e19\u55ea\u3001\u6c1f\u54cc\u5576\u9187\u7684\u7ed3\u6784\u3001\u547d\u540d\u3001\u7406\u5316\u6027\u8d28\u3001\u4f53\u5185\u4ee3\u8c22\u53ca\u4e34\u5e8a\u7528\u9014\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u7cbe\u795e\u75c5\u6307\u4e25\u91cd\u7684\u5fc3\u7406\u969c\u788d\uff0c\u60a3\u8005\u7684\u8ba4\u8bc6\u3001\u60c5\u611f\u3001\u610f\u5fd7\u3001\u52a8\u4f5c\u884c\u4e3a\u7b49\u5fc3\u7406\u6d3b\u52a8\u5747\u53ef\u51fa\u73b0\u6301\u4e45\u7684 &hellip; <a href=\"http:\/\/zydq.1006ss.com\/?p=44590\">\u7ee7\u7eed\u9605\u8bfb <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[70],"tags":[],"class_list":["post-44590","post","type-post","status-publish","format-standard","hentry","category-70"],"_links":{"self":[{"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=\/wp\/v2\/posts\/44590","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=44590"}],"version-history":[{"count":0,"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=\/wp\/v2\/posts\/44590\/revisions"}],"wp:attachment":[{"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=44590"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=44590"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=44590"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}