\u672c\u6587\u7ea6 3500 \u5b57\uff0c\u9605\u8bfb\u7ea6\u9700 7 \u5206\u949f<\/p>\n
\u524d\u4e0d\u4e45\u7684\u6587\u7ae0\u70b9\u8bc4\u4e86 7 \u79cd\u5e38\u89c1\u7684\u5927\u5bb6\u89c9\u5f97\u8865\u9499\u6548\u679c\u597d\u7684\u98df\u7269\uff0c\u9519\u8fc7\u7684\u670b\u53cb\u770b\u8fd9\u91cc\uff1a\u9499\u542b\u91cf\u662f\u725b\u5976\u76849\u500d\u591a\uff0c\u4f46\u6211\u4e0d\u63a8\u8350\u5403\u8fd9\u79cd\u98df\u7269\u8865\u9499\uff01<\/p>\n
\u4e0d\u5c11\u8bfb\u8005\u5728\u540e\u53f0\u7559\u8a00\uff0c\u8981\u6c42\u8bf4\u4e00\u8bf4\u90a3\u4e9b\u300c\u8865\u9499\u4f34\u4fa3\u300d\u7ef4\u751f\u7d20\uff0c\u6bd4\u5982\u201c\u5f15\u9499\u5165\u9aa8\u201d\u7684\u7ef4\u751f\u7d20K\u3002<\/p>\n
\u4eca\u5929\u5c31\u8ddf\u5927\u5bb6\u8bf4\u4e00\u8bf4\u5e02\u9762\u4e0a\u8fd9\u4e9b\u53f7\u79f0\u300c\u8865\u9499\u4f34\u4fa3\u300d\u7684\u7ef4\u751f\u7d20\u662f\u4e0d\u662f\u771f\u7684\u9700\u8981\u8865\u3002<\/p>\n
\u592a\u957f\u4e0d\u770b<\/p>\n
\u7406\u8bba\u4e0a\uff0c\u6b63\u5e38\u996e\u98df\u7684\u5065\u5eb7\u4eba\u7fa4\u662f\u53ef\u4ee5\u4ece\u98df\u7269\u4e2d\u83b7\u53d6\u8db3\u591f\u7684\u9499\u7684\uff0c\u4f46\u5982\u679c\u5b9e\u5728\u505a\u4e0d\u5230\uff0c\u53ef\u4ee5\u8003\u8651\u9499\u8865\u5145\u5242\u3002<\/p>\n
\u7ef4\u751f\u7d20K \u5bf9\u7ef4\u6301\u9aa8\u9abc\u5065\u5eb7\u786e\u5b9e\u6709\u5e2e\u52a9\uff0c\u4f46\u5065\u5eb7\u6210\u5e74\u4eba\u4e00\u822c\u4e0d\u7f3a\u7ef4\u751f\u7d20K \uff0c\u4e0d\u9700\u8981\u989d\u5916\u8865\u3002\u513f\u7ae5\u7ef4\u751f\u7d20K2 \u7f3a\u4e4f\u7684\u60c5\u51b5\u6bd4\u8f83\u666e\u904d\uff0c\u8865\u9499\u540c\u65f6\u8865\u5145\u7ef4\u751f\u7d20K2 \u8fd8\u662f\u6709\u610f\u4e49\u7684\u3002<\/p>\n
\u7ef4\u751f\u7d20D \u81ea\u5df1\u90fd\u5bb9\u6613\u7f3a\uff0c\u786e\u5b9e\u8981\u6ce8\u610f\u201c\u8865\u201d\uff0c\u600e\u4e48\u8865\u3001\u8865\u591a\u5c11\uff0c\u770b\u7b2c\u4e09\u90e8\u5206\u3002<\/p>\n
#1<\/p>\n
\u9499\uff1a\u7f3a\uff1f\u4e0d\u7f3a\uff1f<\/p>\n
\u5728\u8bf4\u300c\u8865\u9499\u4f34\u4fa3\u300d\u4e4b\u524d\uff0c\u5148\u8001\u751f\u5e38\u8c08\u8bf4\u4e00\u8bf4\u4e3b\u89d2\u2014\u2014\u9499\u3002<\/p>\n
\u6211\u4eec\u7f3a\u9499\u5417\uff1f\u771f\u7684\u9700\u8981\u8865\u5417\uff1f\uff08\u5df2\u7ecf\u4e86\u89e3\u7684\u670b\u53cb\u53ef\u4ee5\u76f4\u63a5\u8df3\u8fc7\uff0c\u770b\u540e\u9762\u90e8\u5206\u3002\uff09<\/p>\n
1.1<\/p>\n
\u7406\u8bba\u4e0a\u53ef\u4ee5\u4e0d\u7f3a<\/p>\n
\u5bf9\u4e8e\u5403\u6bcd\u4e73\u6216\u8005\u662f\u914d\u65b9\u5976\u7684\u5b9d\u5b9d\uff0c\u516d\u4e2a\u6708\u5185\u5e76\u4e0d\u9700\u8981\u4efb\u4f55\u989d\u5916\u8865\u9499\u3002<\/p>\n
6\u4e2a\u6708\u5230\u4e00\u5c81\u5de6\u53f3\u7684\u5a74\u5e7c\u513f\uff0c\u6bcf\u5929\u6bcd\u4e73\u6444\u5165\u8fbe\u5230 600 \u6beb\u5347\u4ee5\u4e0a\u6216\u914d\u65b9\u5976\u8fbe\u5230 400 \u6beb\u5347\u4ee5\u4e0a\uff0c\u4e5f\u662f\u4e0d\u4f1a\u7f3a\u9499\u7684\u3002<\/p>\n
\u4e00\u4e2a\u5065\u5eb7\u7684\u6210\u5e74\u4eba\u5982\u679c\u505a\u5230\u996e\u98df\u5747\u8861\uff0c\u4fdd\u8bc1\u4e73\u5236\u54c1\u548c\u7eff\u8272\u852c\u83dc\u7684\u6444\u5165\uff0c\u4e5f\u57fa\u672c\u4e0d\u9700\u8981\u989d\u5916\u8865\u5145\u9499\u8d28\u3002<\/p>\n
\u5f53\u7136\uff0c\u4e5f\u6709\u5bb9\u6613\u51fa\u73b0\u9499\u6444\u5165\u4e0d\u8db3\u7684\u7279\u6b8a\u4eba\u7fa4\uff0c\u4e3b\u8981\u662f\u8001\u5e74\u4eba\uff08\u7279\u522b\u662f70\u5c81\u4ee5\u4e0a\u7537\u6027\u4e0e50\u5c81\u4ee5\u4e0a\u5973\u6027\u7fa4\u4f53\uff09\u3001\u9752\u5c11\u5e74\uff08\u5176\u4e2d9\u5c81-13\u5c81\u7684\u7537\u5b69\u4e0e9-18\u5c81\u7684\u5973\u5b69\u9700\u91cd\u70b9\u5173\u6ce8\uff09\u3001\u5b55\u671f\u54fa\u4e73\u671f\u5973\u6027\u3001\u7d20\u98df\u4eba\u7fa4\u548c\u8fd0\u52a8\u5458\u7b49\u3002<\/p>\n
\u4e0d\u8fc7\uff0c\u7406\u8bba\u662f\u4e00\u56de\u4e8b\uff0c\u5b9e\u9645\u53ef\u80fd\u662f\u53e6\u4e00\u56de\u4e8b\u3002<\/p>\n
1.2<\/p>\n
\u5b9e\u9645\u6444\u5165\u4e0d\u8db3\uff0c\u6709\u98ce\u9669<\/p>\n
\u4e8b\u5b9e\u4e0a\uff0c\u6211\u56fd\u5404\u5e74\u9f84\u5c42\u7684\u4eba\u5e73\u5747\u6bcf\u5929\u9499\u6444\u5165\u91cf\u90fd\u4e0d\u5230\u63a8\u8350\u6444\u5165\u91cf\u7684\u4e00\u534a\uff0c\u6709\u4e9b\u751a\u81f3\u8fde 1\/3 \u90fd\u4e0d\u5230[1]\u3002<\/p>\n
\u6211\u56fd\u7684\u81b3\u98df\u8c03\u67e5\u6570\u636e\u663e\u793a\uff0c1991-2018 \u5e74\u6211\u56fd\u6210\u5e74\u4eba\u5e73\u5747\u9499\u6444\u5165\u91cf\u4e3a 345-412mg\/d\uff0c\u4eba\u7fa4\u9499\u6444\u5165\u91cf\u8ddf 800mg\/d \u7684\u63a8\u8350\u6444\u5165\u91cf\u76f8\u6bd4\u8fd8\u662f\u8f83\u4f4e\u7684[2]\u3002<\/p>\n
\u56fe\u7247\u6765\u81ea\uff1a\u53c2\u8003\u8d44\u6599[2]<\/p>\n
2017\u5e74\u300a\u56fd\u9645\u9aa8\u8d28\u758f\u677e\u300b(Osteoporos Int)\u4e0a\u53d1\u8868\u7684\u4e00\u9879\u7814\u7a76\uff0c\u6c47\u603b\u4e86\u5168\u7403\u591a\u4e2a\u56fd\u5bb6\u7684\u9499\u6444\u5165\u91cf\u60c5\u51b5\uff0c\u6700\u4f4e\u4e00\u6863\u7684\u9c9c\u7ea2\u8272\u662f\u5c0f\u4e8e 400mg\/d\uff0c\u6211\u56fd\u5c31\u5904\u4e8e\u8fd9\u4e00\u6863[3]\u3002 <\/p>\n
\u56fe\u7247\u6765\u81ea\uff1a\u53c2\u8003\u8d44\u6599[4] \u55ef\uff0c\u7801\u662f\u6211\u81ea\u5df1\u6253\u7684\uff0c\u5927\u5bb6\u4f53\u4f1a\u4e00\u4e0b\u533a\u57df\u5c31\u884c<\/p>\n
\u6240\u4ee5\uff0c\u9499\u8fd8\u662f\u8981\u201c\u8865\u201d\u7684\uff0c\u4f46\u9996\u5148\u63a8\u8350\u5927\u5bb6\u4ece\u98df\u7269\u4e2d\u83b7\u53d6\u3002<\/p>\n
1.3<\/p>\n
\u542b\u9499\u4e30\u5bcc\u7684\u98df\u7269<\/p>\n
\u9499\u7684\u4e3b\u8981\u98df\u7269\u6765\u6e90\u4e3a\u5976\u53ca\u5176\u5236\u54c1\u3001\u8c46\u8150\u3001\u53f6\u83dc\u3001\u82b1\u83dc\u548c\u8c46\u835a\u53ca\u8fa3\u6912\u7c7b\u852c\u83dc\u3001\u8d1d\u58f3\u7c7b\u548c\u9c7c\u7c7b\u3001\u67d1\u6a58\u7c7b\u6c34\u679c\u7b49\u3002<\/p>\n
\u5e38\u89c1\u6bcf 100g \u98df\u7269\u7684\u9499\u542b\u91cf\u8303\u56f4\u5982\u4e0b\uff0c\u5927\u5bb6\u53ef\u4ee5\u53c2\u8003\uff1a<\/p>\n
\u9c9c\u5976 100-110mg<\/p>\n
\u8c46\u8150 110-140mg<\/p>\n
\u6df1\u7eff\u8272\u53f6\u83dc\u548c\u82b1\u83dc 50-130mg<\/p>\n
\u67d1\u6a58\u7c7b\u6c34\u679c 20-30mg<\/p>\n
\u8d1d\u58f3\u7c7b\u591a\u9ad8\u4e8e 200mg<\/p>\n
\u9c7c\u7c7b 50-150mg<\/p>\n
\u86cb\u7c7b 50-60mg<\/p>\n
\u755c\u79bd\u8089\u7c7b\u3001\u74dc\u679c\u53ca\u6839\u830e\u7c7b\u852c\u83dc\u548c\u5927\u591a\u6570\u6c34\u679c<\/p>\n
\u4e00\u822c\u5c0f\u4e8e 20mg<\/p>\n
\u4f46\u5982\u679c\u4e0d\u559d\u5976\u4e0d\u5403\u5976\u5236\u54c1\u7684\u8bdd\uff0c\u4e00\u822c\u7684\u996e\u98df\u7ed3\u6784\u9499\u7684\u6444\u5165\u91cf\u5728 300mg \u5de6\u53f3\uff0c\u79bb\u6bcf\u5929 800mg \u7684\u63a8\u8350\u6444\u5165\u91cf\u6709\u4e00\u5b9a\u5dee\u8ddd\u3002\u8fd9\u65f6\uff0c\u53ef\u4ee5\u8003\u8651\u9499\u8865\u5145\u5242\u3002<\/p>\n
\u666e\u901a\u4eba\u670d\u7528\u9499\u5242\uff0c\u4ee5\u9499\u5143\u7d20\u8ba1\uff0c\u6bcf\u5929\u4e0d\u8981\u8d85\u8fc7 1000mg\uff0c\u6709\u4e00\u5b9a\u7684\u8bc1\u636e\u663e\u793a\uff0c\u5927\u5242\u91cf\u9499\u7247\u4f1a\u7565\u5fae\u589e\u52a0\u80be\u7ed3\u77f3\u7684\u98ce\u9669\u3002<\/p>\n
#2<\/p>\n
\u7ef4\u751f\u7d20K\uff1a<\/p>\n
\u771f\u80fd\u8865\u9499\u5165\u9aa8\u5417\uff1f<\/p>\n
\u7ef4\u751f\u7d20K \u662f\u4e00\u79cd\u8102\u6eb6\u6027\u7ef4\u751f\u7d20\uff0c\u6709\u7ef4\u751f\u7d20K1 \u548c\u7ef4\u751f\u7d20K2 \u4e24\u79cd\u5929\u7136\u7c7b\u578b\u3002<\/p>\n
\u7ef4\u751f\u7d20K1 \u53c8\u540d\u53f6\u7eff\u918c\uff0c\u4e3b\u8981\u6e90\u81ea\u7eff\u8272\u852c\u83dc\uff0c\u4e3b\u8981\u529f\u80fd\u662f\u4fc3\u8fdb\u51dd\u8840\u3002<\/p>\n
\u7ef4\u751f\u7d20K2 \u53c8\u540d\u7532\u5948\u918c\uff0c\u4e3b\u8981\u6e90\u81ea\u53d1\u9175\u98df\u54c1\u3001\u8089\u7c7b\u548c\u4e73\u5236\u54c1\uff0c\u4e5f\u53ef\u4ee5\u901a\u8fc7\u80a0\u5185\u7ec6\u83cc\u5408\u6210\uff0c\u5b83\u4e3b\u8981\u53d1\u6325\u9aa8\u9abc\u5065\u5eb7\u6548\u5e94\uff0c\u4fc3\u8fdb\u9aa8\u7ec4\u7ec7\u77ff\u5316\uff0c\u9884\u9632\u9aa8\u6298\u548c\u9aa8\u8d28\u758f\u677e\uff0c\u53e6\u5916\u8fd8\u6709\u964d\u4f4e\u5fc3\u8840\u7ba1\u75be\u75c5\u98ce\u9669\u7684\u6f5c\u5728\u4f5c\u7528\uff0c\u5bf9\u51a0\u72b6\u52a8\u8109\u9499\u5316\u548c\u5fc3\u8840\u7ba1\u75be\u75c5\u6709\u9884\u9632\u4f5c\u7528\u3002<\/p>\n
\u786e\u5b9e\u6709\u7814\u7a76\u53d1\u73b0\u4f4e\u7ef4\u751f\u7d20K\u6444\u5165\u4e0e\u9aa8\u8d28\u758f\u677e\u3001\u9aa8\u6298\u98ce\u9669\u589e\u52a0\u6709\u5173\uff0c\u4e00\u4e9b\u8865\u5145\u5e72\u9884\u8bd5\u9a8c\u4e5f\u8bc1\u660e\uff0c\u8865\u5145\u7ef4\u751f\u7d20K2 \u53ef\u4ee5\u51cf\u5c11\u9aa8\u8d28\u6d41\u5931\uff0c\u964d\u4f4e\u9aa8\u6298\u98ce\u9669\uff0c\u4e5f\u53ef\u4ee5\u9884\u9632\u548c\u6cbb\u7597\u9aa8\u8d28\u758f\u677e\u75c7\u3002\u6b27\u6d32\u98df\u54c1\u5b89\u5168\u5c40\u7b49\u56fd\u9645\u7ec4\u7ec7\u5747\u5df2\u7ecf\u8ba4\u53ef\u7ef4\u751f\u7d20K \u4e0e\u7ef4\u6301\u9aa8\u9abc\u6b63\u5e38\u72b6\u6001\u4e4b\u95f4\u5b58\u5728\u7740\u56e0\u679c\u5173\u7cfb[2]\u3002<\/p>\n
\u6240\u4ee5\uff0c\u5546\u5bb6\u5ba3\u4f20\u7684\u90fd\u662f\u7ef4\u751f\u7d20K2 \uff0c\u8bf4\u5b83\u53ef\u4ee5\u201c\u8865\u9499\u5165\u9aa8\u201d\uff0c\u5927\u6709\u8865\u9499\u4e0d\u8865\u7ef4\u751f\u7d20K2 \u7ea6\u7b49\u4e8e\u6d6a\u8d39\u7684\u610f\u601d\u3002<\/p>\n
2.1<\/p>\n
\u7ef4\u751f\u7d20K2\u4e0d\u5bb9\u6613\u5403\u591f\u5417\uff1f<\/p>\n
\u5728\u5065\u5eb7\u6210\u4eba\u4e2d\uff0c\u81b3\u98df\u4e2d\u7ef4\u751f\u7d20K \u6444\u5165\u4e0d\u8db3\u5e76\u4e0d\u591a\u89c1\uff0c\u56e0\u4e3a\u7ef4\u751f\u7d20K1<\/sub> \u5e7f\u6cdb\u5b58\u5728\u4e8e\u5404\u79cd\u7eff\u8272\u852c\u83dc\u4e2d\uff0c\u800c\u4e14\u80a0\u9053\u7ec6\u83cc\u4e5f\u53c2\u4e0e\u5408\u6210\u7ef4\u751f\u7d20K2<\/sub>\uff0c\u7ef4\u751f\u7d20K2 \u8fd8\u53ef\u901a\u8fc7\u53d1\u9175\u98df\u54c1\u3001\u8089\u7c7b\u548c\u4e73\u5236\u54c1\u83b7\u53d6[5]\u3002<\/p>\n \u6210\u4eba\u7ef4\u751f\u7d20K \u7f3a\u4e4f\u5f80\u5f80\u7ee7\u53d1\u4e8e\u80c3\u80a0\u9053\u75be\u75c5\u6216\u836f\u7269\u6cbb\u7597\uff0c\u6bd4\u5982\u80c3\u80a0\u9053\u529f\u80fd\u7d0a\u4e71\u3001\u809d\u80c6\u75be\u75c5\u5bfc\u81f4\u7684\u8102\u80aa\u5438\u6536\u5f02\u5e38\u3002\u80c3\u80a0\u9053\u83cc\u7fa4\u7d0a\u4e71\u548c\u957f\u671f\u4f7f\u7528\u6297\u751f\u7d20\u4e5f\u4f1a\u5bfc\u81f4\u80a0\u9053\u5fae\u751f\u7269\u5408\u6210\u7ef4\u751f\u7d20K2\u969c\u788d\u7b49[2]\u3002<\/p>\n \u4e0d\u8fc7\uff0c\u5bf9\u4e8e\u513f\u7ae5\u6765\u8bf4\uff0c\u60c5\u51b5\u6709\u70b9\u4e0d\u4e00\u6837\u3002<\/p>\n \u6c88\u9633\u7684\u4e00\u9879\u7814\u7a76\uff0c\u6d4b\u5b9a\u4e86 1732 \u540d 0-14 \u5c81\u513f\u7ae5\u7684\u8840\u6e05\u7ef4\u751f\u7d20K2 \u6c34\u5e73\uff0c\u53d1\u73b0\u7ef4\u751f\u7d20K2 \u7f3a\u4e4f\u7387* \u9ad8\u8fbe 52.31%[13]\u3002\u53e6\u4e24\u9879\u5317\u4eac\u53ca\u5b89\u5fbd\u7684\u7814\u7a76\u4e5f\u53d1\u73b0\uff0c 0-14 \u5c81\u513f\u7ae5\u4e2d\u7ef4\u751f\u7d20K2<\/sub> \u7f3a\u4e4f\u7387\u666e\u904d\u8f83\u9ad8\uff0c\u90fd\u8d85\u8fc7\u4e86 50%[14-15]\u3002<\/p>\n *\u53c2\u8003\u5fb7\u56fd\u67cf\u6797\u533b\u5b66\u8bca\u65ad\u68c0\u9a8c\u4e2d\u5fc3\u5b9e\u9a8c\u5ba4\u6807\u51c6\uff0c \u5c06\u8840\u6e05 VitK2<0.1 ng\/mL \u5b9a\u4e49\u4e3a\u7f3a\u4e4f\u3002<\/p>\n \u6240\u4ee5\uff0c\u5065\u5eb7\u6210\u5e74\u4eba\u6765\u8bf4\uff0c\u8865\u9499\u4e0d\u4e00\u5b9a\u9700\u8981\u540c\u65f6\u8865\u5145\u7ef4\u751f\u7d20K2<\/sub> \uff0c\u5c31\u7b97\u4f60\u4ece\u98df\u7269\u4e2d\u5403\u4e0d\u591f\uff0c\u4f60\u7684\u80a0\u9053\u83cc\u7fa4\u4e5f\u80fd\u201c\u5236\u9020\u201d\u3002<\/p>\n \u5bf9\u513f\u7ae5\u6765\u8bf4\uff0c\u8865\u9499\u540c\u65f6\u8865\u5145\u7ef4\u751f\u7d20K2<\/sub> \u8fd8\u662f\u6709\u4e00\u5b9a\u610f\u4e49\u7684\u3002\u4ed6\u4eec\u53ef\u80fd\u56e0\u4e3a\u6311\u98df\u3001\u80a0\u9053\u83cc\u7fa4\u5bb9\u6613\u5931\u8c03\uff08\u6bd4\u5982\u51ac\u6625\u5b63\u547c\u5438\u9053\u75be\u75c5\u9ad8\u53d1\uff0c\u957f\u65f6\u95f4\u5e94\u7528\u6297\u751f\u7d20\u7b49\uff09\u7b49\u539f\u56e0\u6bd4\u8f83\u5bb9\u6613\u51fa\u73b0\u7ef4\u751f\u7d20K2 \u7f3a\u4e4f\u3002<\/p>\n 2.2<\/p>\n \u5e94\u8be5\u5403\u591a\u5c11\u5462\uff1f<\/p>\n \u8bf4\u5b9e\u8bdd\uff0c\u76ee\u524d\u7f3a\u4e4f\u6709\u5173\u4eba\u4f53\u5bf9\u7ef4\u751f\u7d20K \u9700\u8981\u91cf\u7684\u7814\u7a76\u8bc1\u636e\uff0c\u6211\u56fd\u4e5f\u53ea\u662f\u57fa\u4e8e\u6d41\u884c\u75c5\u5b66\u8c03\u67e5\u83b7\u5f97\u7684\u5065\u5eb7\u4eba\u7fa4\u81b3\u98df\u7ef4\u751f\u7d20K \u6444\u5165\u91cf\u6570\u636e\uff0c\u5236\u5b9a\u4e86\u81b3\u98df\u7ef4\u751f\u7d20K \u7684\u9002\u5b9c\u6444\u5165\u91cf\uff08AI\uff0c\u901a\u8fc7\u89c2\u5bdf\u6216\u8bd5\u9a8c\u83b7\u5f97\u7684\u5065\u5eb7\u7fa4\u4f53\u67d0\u79cd\u8425\u517b\u7d20\u7684\u6444\u5165\u91cf\uff09\u503c\uff0c\u6ca1\u6709\u5236\u5b9a\u63a8\u8350\u6444\u5165\u91cf\uff08RNI\uff09\u548c\u53ef\u8010\u53d7\u6700\u9ad8\u5242\u91cf\uff08UL\uff09\u3002<\/p>\n \u6211\u628a\u5404\u5e74\u9f84\u6bb5\u7684\u9002\u5b9c\u6444\u5165\u91cf\u505a\u4e86\u5f20\u8868\uff0c\u5927\u5bb6\u53ef\u4ee5\u53c2\u8003\u4e0b\u3002<\/p>\n 2.3<\/p>\n \u5df2\u7ecf\u4e70\u4e86\u7684\u600e\u4e48\u529e\uff1f<\/p>\n \u5df2\u7ecf\u4e70\u4e86\u7684\u6210\u5e74\u670b\u53cb\uff0c\u770b\u7740\u624b\u91cc\u7684\u7ef4\u751f\u7d20K2 \u8865\u5145\u5242\u6216\u6dfb\u52a0\u4e86\u7ef4\u751f\u7d20K2 \u7684\u9499\u8865\u5145\u5242\uff0c\u53ef\u80fd\u4f1a\u9677\u5165\u7ea0\u7ed3\uff1a\u5403\u5427\uff0c\u6015\u8fc7\u91cf\uff0c\u4e0d\u5403\u5427\uff0c\u94b1\u90fd\u82b1\u4e86\u96be\u9053\u8981\u6d6a\u8d39\uff1f<\/p>\n \u8ddf\u8fd9\u4e9b\u670b\u53cb\u8bf4\u4e00\u4e2a\u597d\u6d88\u606f\u3002<\/p>\n \u76ee\u524d\u6ca1\u6709\u4eba\u4f53\u7ef4\u751f\u7d20K \u6444\u5165\u8fc7\u91cf\u4ea7\u751f\u4e0d\u826f\u53cd\u5e94\u7684\u62a5\u9053\u3002<\/p>\n \u91c7\u7528MK-4\uff08\u7ef4\u751f\u7d20K2 \u7684\u4e00\u79cd\u5f62\u5f0f\uff09\u6cbb\u7597\u9aa8\u8d28\u758f\u677e\u65f6\uff0c\u8865\u5145\u5242\u91cf\u8fbe\u5230 45mg\/d \u65f6\u4ecd\u6ca1\u6709\u89c2\u5bdf\u5230\u4e0d\u826f\u53cd\u5e94\uff0c\u4eba\u4f53\u6301\u7eed\u8865\u5145 10mg\/d \u7684\u7ef4\u751f\u7d20K1 \u4e5f\u6ca1\u6709\u53d1\u73b0\u660e\u663e\u526f\u4f5c\u7528\u3002<\/p>\n \u56e0\u4e3a\u6ca1\u6709\u660e\u786e\u7684\u6bd2\u6027\u62a5\u9053\uff0c\u56fd\u9645\u7ec4\u7ec7\u548c\u5404\u56fd\u90fd\u6ca1\u6709\u5236\u5b9a\u7ef4\u751f\u7d20K \u7684\u53ef\u8010\u53d7\u6700\u9ad8\u5242\u91cf\uff08UL\uff09\u3002<\/p>\n \u5df2\u7ecf\u4e70\u4e86\u7ef4\u751f\u7d20K2 \u8865\u5145\u5242\u6216\u6dfb\u52a0\u4e86\u7ef4\u751f\u7d20K2 \u7684\u9499\u8865\u5145\u5242\u7684\u670b\u53cb\uff0c\u53ef\u4ee5\u7ee7\u7eed\u5403\uff0c\u6211\u5e2e\u4f60\u7ffb\u770b\u4e86\u5404\u5927\u7535\u5546\u5e73\u53f0\u552e\u5356\u7684\u4ea7\u54c1\uff0c\u6dfb\u52a0\u7684\u7ef4\u751f\u7d20K2 \u7684\u5242\u91cf\u5e76\u4e0d\u9ad8\uff08\u5927\u90e8\u5206\u90fd\u5728\u9002\u5b9c\u63a8\u8350\u91cf\u4ee5\u4e0b\uff09\uff0c\u8fd8\u662f\u975e\u5e38\u5b89\u5168\u7684\u3002<\/p>\n \u81f3\u4e8e\u4f60\u4ee5\u540e\u4e70\u4e0d\u4e70\uff0c\u5c31\u81ea\u5df1\u51b3\u5b9a\u5427\u3002<\/p>\n #3<\/p>\n \u7ef4\u751f\u7d20D\uff1a<\/p>\n \u81ea\u5df1\u90fd\u5bb9\u6613\u7f3a<\/p>\n \u7ef4\u751f\u7d20D \u4e5f\u662f\u4e00\u4e2a\u6211\u53cd\u590d\u8bf4\u7684\u8bdd\u9898\uff0c\u5b83\u5728\u7ef4\u6301\u8840\u6e05\u9499\u78f7\u6c34\u5e73\u7a33\u5b9a\u4e2d\u53d1\u6325\u7740\u91cd\u8981\u4f5c\u7528\uff0c\u5bf9\u9aa8\u9abc\u6b63\u5e38\u77ff\u5316\u8fc7\u7a0b\u3001\u808c\u8089\u6536\u7f29\u3001\u795e\u7ecf\u4f20\u5bfc\u4ee5\u53ca\u7ec6\u80de\u57fa\u672c\u529f\u80fd\u7b49\u90fd\u662f\u5fc5\u9700\u7684[2]\u3002<\/p>\n \u4f46\u7ef4\u751f\u7d20D \u7f3a\u4e4f\u4e5f\u662f\u4e00\u4e2a\u4e16\u754c\u6027\u7684\u95ee\u9898\uff0c\u7279\u522b\u662f\u5bf9\u4e8e\u751f\u6d3b\u5728\u9ad8\u7eac\u5ea6\u5730\u533a\u6216\u8005\u76ae\u80a4\u65e5\u5e38\u66dd\u9732\u8f83\u5c11\u7684\u4eba\u7fa4\u3002<\/p>\n \u7ef4\u751f\u4e92D \u7f3a\u4e4f\u672c\u8eab\u5c31\u53ef\u80fd\u5bfc\u81f4\u9aa8\u9499\u8425\u517b\u4e0d\u826f\u3002<\/p>\n 3.1<\/p>\n \u7ef4\u751f\u7d20D \u4e3a\u4ec0\u4e48\u4f1a\u7f3a\uff1f<\/p>\n \u7ef4\u751f\u7d20D \u7f3a\u4e4f\u7684\u4e3b\u8981\u539f\u56e0\u5c31\u662f\uff1a\u9633\u5149\u76f4\u63a5\u66b4\u9732\u4e0d\u8db3\u3001\u81b3\u98df\u4e2d\u7f3a\u4e4f\u7ef4\u751f\u7d20D\u3002\u4e3b\u8981\u8fd8\u662f\u9633\u5149\u66b4\u9732\u4e0d\u8db3\uff0c\u6bd5\u7adf\u4eba\u4f53\u6240\u9700\u7ef4\u751f\u7d20D\u7ea6 90% \u7531\u76ae\u80a4\u5408\u6210\u3002<\/p>\n \u4e00\u65b9\u9762\uff0c\u57ce\u5e02\u751f\u6d3b\u8ba9\u5927\u5bb6\u7684\u6237\u5916\u6d3b\u52a8\u65f6\u95f4\u5927\u5927\u51cf\u5c11\uff0c\u53e6\u4e00\u65b9\u9762\uff0c\u5927\u5bb6\u56e0\u4e3a\u5bb3\u6015\u65e5\u6652\u5e26\u6765\u7684\u5149\u8001\u5316\u3001\u5149\u635f\u4f24\uff0c\u9632\u6652\u63aa\u65bd\u4e5f\u8d8a\u6765\u8d8a\u4e25\u683c\u3002\u518d\u52a0\u4e0a\u996e\u98df\u4e2d\u83b7\u5f97\u7684\u7ef4\u751f\u7d20D \u4e5f\u4e0d\u591f\uff0c\u4e5f\u5c31\u5bfc\u81f4\u4e86\u7ef4\u751f\u7d20D \u4e0d\u8db3\u3001\u7f3a\u4e4f\u3002<\/p>\n \u4e2d\u56fd\u5c45\u6c11\u7ef4\u751f\u7d20D \u4e0d\u8db3\u3001\u7f3a\u4e4f\u7684\u95ee\u9898\u666e\u904d\u5b58\u5728\uff0c\u5404\u5e74\u9f84\u5c42\u7ef4\u751f\u7d20D \u4e0d\u8db3\u53ca\u7f3a\u4e4f\u7684\u5360\u6bd4\u90fd\u63a5\u8fd1\u751a\u81f3\u8d85\u8fc7 50%[6-10]\u3002\u5373\u4f7f\u5728\u65e5\u5149\u5145\u6c9b\u7684\u5357\u65b9\u5730\u533a\u4e5f\u662f\u4e00\u6837\u3002<\/p>\n \u8001\u5e74\u4eba\u3001\u5b66\u9f84\u513f\u7ae5\u548c\u5b55\u5987\u90fd\u662f\u7ef4\u751f\u7d20D \u7f3a\u4e4f\u7684\u9ad8\u5371\u4eba\u7fa4\u3002<\/p>\n 3.2<\/p>\n \u7ef4\u751f\u7d20D \u5e94\u8be5\u5403\u591a\u5c11\uff1f<\/p>\n \u6211\u4eec\u4ece\u81b3\u98df\u4e2d\u5927\u6982\u80fd\u83b7\u53d6\u8eab\u4f53\u6240\u9700\u7ef4\u751f\u7d20D\u7684 10% \u3002<\/p>\n \u975e\u5f3a\u5316\u98df\u54c1\u4e2d\u5929\u7136\u7ef4\u751f\u7d20D \u7684\u6765\u6e90\u4e3b\u8981\u662f\u52a8\u7269\u6027\u98df\u54c1\uff0c\u5982\u9ad8\u8102\u6d77\u9c7c\u3001\u52a8\u7269\u809d\u810f\u3001\u86cb\u9ec4\u7b49\u3002<\/p>\n \u5f3a\u5316\u98df\u54c1\u5219\u6709\u914d\u65b9\u5976\u7c89\u3001\u5f3a\u5316\u7ef4\u751f\u7d20A\/D \u7684\u725b\u5976\u7b49\u3002<\/p>\n 3.3<\/p>\n \u7ef4\u751f\u7d20D \u600e\u4e48\u8865\uff1f<\/p>\n \u589e\u52a0\u7ef4\u751f\u7d20D \u6c34\u5e73\u7684\u9014\u5f84\u6709\u4e24\u79cd\uff0c\u6652\u592a\u9633\u662f\u66f4\u7ecf\u6d4e\u3001\u65b9\u4fbf\u7684\u529e\u6cd5\uff0c\u4e0d\u8fc7\u6211\u4e2a\u4eba\u66f4\u63a8\u8350\u901a\u8fc7\u996e\u98df\uff0c\u5c24\u5176\u662f\u4f7f\u7528\u8865\u5145\u5242\u6765\u8865\u5145\u3002<\/p>\n \u6652\u592a\u9633<\/p>\n \u589e\u52a0\u6237\u5916\u6d3b\u52a8\u65f6\u95f4\uff0c\u5bf9\u4e8e\u7ef4\u751f\u7d20D\u6b63\u5e38\u548c\u4e0d\u8db3\u7684\u4eba\u6765\u8bf4\uff0c\u6bcf\u5929\u63a5\u53d7\u65e5\u5149\u7167\u5c04\u7ea6 30min\uff0c\u5373\u53ef\u6ee1\u8db3\u4eba\u4f53\u7ef4\u751f\u7d20D\u7684\u9700\u6c42\u3002\u7ef4\u751f\u7d20D \u7f3a\u4e4f\u7684\u4eba\u7fa4\u53ef\u80fd\u5c31\u9700\u8981\u66f4\u957f\u7684\u6237\u5916\u6d3b\u52a8\u65f6\u95f4\uff0c1-2\u5c0f\u65f6\u3002<\/p>\n \u6652\u53cc\u4e0a\u80a2\u3001\u53cc\u4e0b\u80a2\uff0c\u66b4\u9732\u7684\u76ae\u80a4\u9762\u79ef\u5c31\u591f\u4e86\uff0c\u4e0d\u7528\u975e\u5f97\u6652\u8138\u3002\u201c\u8865\u201d\u7ef4\u751f\u7d20D \u4e5f\u8981\u6ce8\u610f\u4fdd\u62a4\u76ae\u80a4\uff0c\u9632\u6b62\u6652\u4f24\uff0c\u907f\u514d\u5267\u70c8\u65e5\u5149\u7167\u5c04\u4ee5\u53ca\u8fc7\u957f\u65f6\u95f4\u7684\u65e5\u5149\u66b4\u9732[11-12]\u3002\u5728\u6811\u836b\u4e0b\uff0c\u7d2b\u5916\u7ebf\u7684\u6563\u5c04\u4e5f\u80fd\u8d77\u5230\u5408\u6210\u7ef4\u751f\u7d20D \u7684\u4f5c\u7528\u3002<\/p>\n \u8865\u5145\u5242<\/p>\n \u5bf9\u6ca1\u529e\u6cd5\u6709\u5145\u5206\u9633\u5149\u66b4\u9732\u7684\u4eba\u6765\u8bf4\uff0c\u4ece\u98df\u7269\u4e2d\u83b7\u5f97\u7684\u7ef4\u751f\u7d20D \u53c8\u5f88\u96be\u6ee1\u8db3\u8eab\u4f53\u6240\u9700\uff0c\u5c31\u53ef\u4ee5\u8003\u8651\u7ef4\u751f\u7d20D \u8865\u5145\u5242\u3002<\/p>\n \u81f3\u4e8e\u5403\u591a\u5c11\uff0c\u6bd4\u8f83\u7cbe\u786e\u7684\u9009\u62e9\u662f\u8bc4\u4f30\u4f60\u901a\u8fc7\u65e5\u6652\u548c\u996e\u98df\u4e2d\u83b7\u5f97\u4e86\u591a\u5c11\u7ef4\u751f\u7d20D\uff0c\u7136\u540e\u7528\u63a8\u8350\u6444\u5165\u91cf\u51cf\u53bb\u8fd9\u4e2a\u6570\u503c\uff0c\u5c31\u662f\u7ef4\u751f\u7d20D \u8865\u5145\u5242\u7684\u5242\u91cf\u3002<\/p>\n \u4f46\u8fd9\u5f88\u5c11\u6709\u4eba\u80fd\u505a\u5230\uff0c\u901a\u5e38\u6765\u8bf4\uff0c\u7ef4\u751f\u7d20D \u6b63\u5e38*\u7684\u4eba\u51fa\u4e8e\u9884\u9632\u7684\u8003\u8651\u8865\u5145\uff0c\u90a3\u6bd4\u8f83\u7b80\u5355\u65b9\u4fbf\u7684\u505a\u6cd5\u662f\u6bcf\u5929\u5403 400 IU \u7ef4\u751f\u7d20D \u8865\u5145\u5242\uff0c\u662f\u5f88\u5b89\u5168\u7684\u3002<\/p>\n *\u4e00\u822c\u6765\u8bf4\uff0c\u7ef4\u751f\u7d20D \u5145\u8db3\u7684\u6807\u51c6\u662f\u8840\u6e05 25(OH)D \u226550 nmol\/L<\/p>\n \u5982\u679c\u662f\u5b55\u5987\u3001\u6df1\u80a4\u8272\u4eba\u7fa4\u3001\u80a5\u80d6\u8005\u3001\u513f\u7ae5\u548c\u8001\u5e74\u4eba\u7b49\u7ef4\u751f\u7d20D \u7f3a\u4e4f\u7684\u9ad8\u98ce\u9669\u4eba\u7fa4\uff0c\u5242\u91cf\u8fd8\u53ef\u4ee5\u66f4\u9ad8\u4e00\u70b9\u3002<\/p>\n \u4f46\u5982\u679c\u5df2\u7ecf\u51fa\u73b0\u4e0d\u8db3\u751a\u81f3\u662f\u7f3a\u4e4f\uff0c\u4e3a\u4e86\u628a\u8840\u6e05 25(OH)D \u62c9\u56de 50 nmol\/L \u6c34\u5e73\uff0c\u6cbb\u7597\u5242\u91cf\u53ef\u80fd\u4f1a\u5f88\u5927\uff0c\u6700\u5c0f\u6cbb\u7597\u5242\u91cf\u90fd\u80fd\u8fbe\u5230 2000IU\/d \uff0c\u9ad8\u7684\u53ef\u4ee5\u8fbe\u5230 6000IU\/d \uff0c\u8fd9\u6837\u6cbb\u7597\u4e24\u4e2a\u6708\uff0c\u5e76\u4e14\u901a\u8fc7\u68c0\u6d4b\u786e\u8ba4\u5b8c\u6210\u521d\u6b65\u6cbb\u7597\u4e4b\u540e\uff0c\u6bcf\u5929\u5927\u6982\u4e5f\u5f97\u9700\u8981\u6444\u51651500~2000IU \u6765\u7ef4\u6301\u7ef4\u751f\u7d20D\u6c34\u5e73\u3002<\/p>\n \u4f46\u4e00\u822c\u4eba\u6bcf\u5929\u5403\u8d85\u8fc74000IU\uff0c\u4e0d\u4e00\u5b9a\u80fd\u589e\u52a0\u5065\u5eb7\u6536\u76ca\uff0c\u76f8\u53cd\u4f1a\u589e\u52a0\u4e2d\u6bd2\u7684\u98ce\u9669\u3002<\/p>\n \u4f60\u6709\u5728\u8865\u9499\u5417\uff1f\u662f\u5426\u8003\u8651\u8fc7\u8fd9\u4e9b\u300c\u8865\u9499\u4f34\u4fa3\u300d\u5462\uff1f<\/p>\n \u53c2\u8003\u8d44\u6599<\/p>\n [1] \u4e2d\u56fd\u8425\u517b\u5b66\u4f1a\u7f16\u8457.\u4e2d\u56fd\u5c45\u6c11\u81b3\u98df\u6307\u5357\u79d1\u5b66\u7814\u7a76\u62a5\u544a\uff082021\uff09[M].\u4eba\u6c11\u536b\u751f\u51fa\u7248\u793e,2021.<\/p>\n [2] \u4e2d\u56fd\u8425\u517b\u5b66\u4f1a.\u4e2d\u56fd\u5c45\u6c11\u81b3\u98df\u8425\u517b\u7d20\u53c2\u8003\u6444\u5165\u91cf\uff082023\u7248\uff09[M].\u4eba\u6c11\u536b\u751f\u51fa\u7248\u793e,2023.<\/p>\n [3] Balk E M , Adam G P , Langberg V N ,et al.Global dietary calcium intake among adults: a systematic review[J].Osteoporosis International, 2017, 28(Suppl 2):3315-3324.DOI:10.1007\/s00198-017-4230-x.<\/p>\n [4] Global Dietary Calcium Intake Among Adults[EB\/OL]. [2024-09-06]. https:\/\/www.undation\/educational-hub\/topic\/calcium\/calcium-map<\/p>\n [5] \u9ed8\u6c99\u4e1c\u8bca\u7597\u624b\u518c\uff08\u533b\u5b66\u4e13\u4e1a\u4eba\u58eb\u7248\uff09-\u7ef4\u751f\u7d20K\u7f3a\u4e4f\u75c7[EB\/OL]. (2022-11)[2024-09-06]. https:\/\/www.\/professional\/nutritional-disorders\/vitamin-deficiency-dependency-and-toxicity\/vitamin-k-deficiency<\/p>\n [6] \u9ad8\u6772,\u9648\u6653.\u4e0a\u6d77\u5730\u533a\u6210\u4eba\u7ef4\u751f\u7d20D\u6c34\u5e73\u4e0e\u6027\u522b\u3001\u5e74\u9f84\u3001\u5b63\u8282\u7684\u5173\u7cfb[J].\u4e2d\u56fd\u9aa8\u8d28\u758f\u677e\u6742\u5fd7,2022,28(02):280-284.<\/p>\n [7] \u9648\u8d85,\u5218\u5fd7\u8d85,\u795d\u6c38\u521a,\u8096\u8f89\u706f,\u90ed\u83f2\u5b87,\u5f20\u4e07\u7965,\u5362\u901a,\u9f50\u78ca,\u67f3\u6839\u54f2.\u7ef4\u751f\u7d20D\u7684\u6700\u65b0\u7814\u7a76\u8fdb\u5c55[J].\u4e2d\u56fd\u9aa8\u8d28\u758f\u677e\u6742\u5fd7,2018,24(10):1390-1395.<\/p>\n [8] \u9ad8\u5029,\u5218\u626c.\u4e2d\u56fd\u4eba\u7fa4\u7ef4\u751f\u7d20D\u7f3a\u4e4f\u7814\u7a76\u8fdb\u5c55[J].\u4e2d\u56fd\u516c\u5171\u536b\u751f,2012,28(12):1670-1672.<\/p>\n [9] \u6c99\u6021\u6885,\u9ec4\u68a8\u715c,\u738b\u777f\u714a\u7b49.2016\u20142018\u5e74\u5317\u4eac\u5e02\u5b66\u9f84\u513f\u7ae5\u7ef4\u751f\u7d20D\u8425\u517b\u72b6\u51b5\u53ca\u5176\u5206\u5e03\u7279\u70b9[J].\u536b\u751f\u7814\u7a76,2022,51(06):969-974.<\/p>\n [10] \u4f55\u68a6\u6d01,\u90b9\u8273,\u9ec4\u674e\u6625\u7b49.2018\u5e74\u6d59\u6c5f\u7701\u6210\u4eba\u7ef4\u751f\u7d20D\u8425\u517b\u72b6\u51b5\u53ca\u5f71\u54cd\u56e0\u7d20[J].\u536b\u751f\u7814\u7a76,2022,51(05):844-848.<\/p>\n [11] \u4e2d\u56fd\u8425\u517b\u5b66\u4f1a\u5065\u5eb7\u7ba1\u7406\u5206\u4f1a. \u7ef4\u751f\u7d20D\u8425\u517b\u72b6\u51b5\u8bc4\u4ef7\u53ca\u6539\u5584\u4e13\u5bb6\u5171\u8bc6 [J] . \u4e2d\u534e\u5065\u5eb7\u7ba1\u7406\u5b66\u6742\u5fd7, 2023, 17(4) : 245-252. <\/p>\n [12] \u5ed6\u7965\u9e4f,\u5f20\u589e\u5229,\u5f20\u7ea2\u7ea2\u7b49.\u7ef4\u751f\u7d20D\u4e0e\u6210\u5e74\u4eba\u9aa8\u9abc\u5065\u5eb7\u5e94\u7528\u6307\u5357(2014\u5e74\u6807\u51c6\u7248)[J].\u4e2d\u56fd\u9aa8\u8d28\u758f\u677e\u6742\u5fd7,2014,20(09):1011-1030.<\/p>\n [13] \u675c\u957f\u79c0,\u674e\u5a1c.1732\u4f8b\u513f\u7ae5\u8840\u6e05\u7ef4\u751f\u7d20K_2\u4e34\u5e8a\u5206\u6790\u53ca\u5176\u4e0e\u9aa8\u4ee3\u8c22\u6807\u5fd7\u7269\u5173\u7cfb\u7684\u7814\u7a76[J].\u4e2d\u56fd\u5f53\u4ee3\u513f\u79d1\u6742\u5fd7,2022,24(10):1130-1135.<\/p>\n [14] \u535c\u7965\u82b3,\u4f55\u6d0b,\u7a0b\u82ac\u82ac,\u7b49.\u5317\u4eac\u57ce\u5317\u5730\u533a0\uff5e14\u5c81\u513f\u7ae5\u7ef4\u751f\u7d20K\u8425\u517b\u72b6\u51b5\u7684\u89c2\u5bdf\u7814\u7a76[J].\u4e2d\u56fd\u5987\u5e7c\u5065\u5eb7\u7814\u7a76,2024,35(08):44-50.<\/p>\n [15] \u6768\u5a77\u5a77,\u5218\u6653\u9759.\u77ee\u5c0f\u75c7\u60a3\u513f\u7ef4\u751f\u7d20K2\u6c34\u5e73\u4e0e\u9aa8\u4ee3\u8c22\u4e4b\u95f4\u5173\u7cfb\u7684\u7814\u7a76[J].\u68c0\u9a8c\u533b\u5b66\u4e0e\u4e34\u5e8a,2022,19(17):2393-2397.<\/p>\n","protected":false},"excerpt":{"rendered":" \u672c\u6587\u7ea6 3500 \u5b57\uff0c\u9605\u8bfb\u7ea6\u9700 7 \u5206\u949f \u524d\u4e0d\u4e45\u7684\u6587\u7ae0\u70b9\u8bc4\u4e86 7 \u79cd\u5e38\u89c1\u7684\u5927\u5bb6\u89c9 … \u7ee7\u7eed\u9605\u8bfb