{"id":40288,"date":"2024-08-29T05:13:19","date_gmt":"2024-08-29T05:13:19","guid":{"rendered":"https:\/\/zydq.1006ss.com\/?p=40288"},"modified":"2024-08-29T05:13:19","modified_gmt":"2024-08-29T05:13:19","slug":"%e5%ae%b6%e5%b8%b8%e5%8f%af%e7%94%a8%e7%9a%84%e6%b9%bf%e7%96%b9%e5%a4%96%e6%b4%97%e6%96%b9-%e7%a5%9b%e9%a3%8e%e6%b6%a6%e7%87%a5%e6%ad%a2%e7%97%92%e6%ba%bb%e6%b8%8d%e6%96%b9","status":"publish","type":"post","link":"http:\/\/zydq.1006ss.com\/?p=40288","title":{"rendered":"\u5bb6\u5e38\u53ef\u7528\u7684\u6e7f\u75b9\u5916\u6d17\u65b9\u2014\u2014\u795b\u98ce\u6da6\u71e5\u6b62\u75d2\u6ebb\u6e0d\u65b9"},"content":{"rendered":"

  <\/p>\n

      \u6ebb\u6e0d\u6cd5\u662f\u4e2d\u533b\u4e00\u79cd\u5916\u6cbb\u6cd5\uff0c\u4e3b\u8981\u7528\u4e8e\u76ae\u80a4\u75c5\u7684\u6cbb\u7597\uff0c\u4e5f\u662f\u767e\u59d3\u6700\u5e38\u7528\u6765\u6cbb\u7597\u76ae\u80a4\u75c5\u7684\u65b9\u6cd5\uff0c\u901a\u5e38\u5c06\u8349\u836f\u6216\u5176\u4ed6\u836f\u7269\u5236\u5907\u6210\u818f\u72b6\u3001\u7cca\u72b6\u6216\u6db2\u4f53\u5f62\u5f0f\uff0c\u7136\u540e\u76f4\u63a5\u6d82\u62b9\u5728\u60a3\u5904\uff0c\u901a\u8fc7\u76ae\u80a4\u5438\u6536\u836f\u7269\u6210\u5206\u6765\u6cbb\u7597\u75be\u75c5\u3002\u795b\u98ce\u6da6\u71e5\u6b62\u75d2\u6ebb\u6e0d\u65b9\u7531\u6c5f\u897f\u4e2d\u533b\u836f\u5927\u5b66\u55bb\u6587\u7403\u6559\u6388\u63d0\u51fa\uff0c\u5305\u542b\u9999\u9644\u3001\u7802\u4ec1\u3001\u8346\u82a5\u3001\u82e6\u53c2\u3001\u9a6c\u9f7f\u82cb\u3001\u767e\u90e8\u3001\u5343\u91cc\u5149\u3001\u8335\u9648\u3001\u9632\u98ce\u3001\u5730\u80a4\u5b50\u3001\u86c7\u5e8a\u5b50\u3001\u5a01\u7075\u4ed9\u3001\u6843\u4ec1\u3001\u5f53\u5f52\u7b4914\u5473\u4f20\u7edf\u8349\u836f\u7684\u65b9\u5242\uff0c\u4e3b\u8981\u7528\u4e8e\u6cbb\u7597\u6162\u6027\u6e7f\u75b9\u6216\u7279\u5e94\u6027\u76ae\u708e\u3002\u6700\u8fd1\u6709\u7814\u7a76\u62a5\u9053\u795b\u98ce\u6da6\u71e5\u6b62\u75d2\u6ebb\u6e0d\u65b9\u5bf9\u7279\u5e94\u6027\u76ae\u708e\u6a21\u578b\u5c0f\u9f20\u5177\u6709\u6539\u5584\u4f5c\u7528\u3002\u795b\u98ce\u6da6\u71e5\u6b62\u75d2\u6ebb\u6e0d\u65b9\u80fd\u663e\u8457\u6539\u5584\u5c0f\u9f20\u7684\u76ae\u80a4\u75c5\u53d8\uff0c\u964d\u4f4e\u75c5\u7406\u5b66\u635f\u4f24\u8bc4\u5206\uff0c\u51cf\u5c11\u8840\u6e05\u548c\u76ae\u80a4\u7ec4\u7ec7\u4e2d\u7684\u708e\u75c7\u56e0\u5b50TNF-\u03b1\u3001IL-4\u3001IL-6\u6c34\u5e73\uff0c\u5e76\u6291\u5236TLR4\/NF-\u03baB\u4fe1\u53f7\u901a\u8def\u7684\u6d3b\u5316\u30101\u3011\u3002<\/p>\n

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  • \n

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  • \n

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  • \n

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  • \n

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          TNF-\u03b1\uff08\u80bf\u7624\u574f\u6b7b\u56e0\u5b50\u03b1\uff09\u3001IL-4\uff08\u767d\u7ec6\u80de\u4ecb\u7d204\uff09\u3001IL-6\uff08\u767d\u7ec6\u80de\u4ecb\u7d206\uff09\u662f\u4e09\u79cd\u91cd\u8981\u7684\u7ec6\u80de\u56e0\u5b50\uff0c\u5728\u7279\u5e94\u6027\u76ae\u708e\u4e2d\u626e\u6f14\u5173\u952e\u89d2\u8272\u3002\u91d1\u857e\u68c0\u6d4b\u4e86\u8840\u6e05\u548c\u76ae\u80a4\u4e2d TNF-\u03b1\u3001IL-4\u3001IL-6\u7684\u6d53\u5ea6\u4e0e\u57fa\u56e0\uff0cELISA\u548cqRT-PCR\u6cd5\u68c0\u6d4b\u53d1\u73b0\u7279\u5e94\u6027\u76ae\u708e\u6a21\u578b\u7ec4\u4e2dTNF-\u03b1\u3001IL-4\u3001IL-6\u7684\u6d53\u5ea6\u548c\u57fa\u56e0\u90fd\u663e\u8457\u5347\u9ad8\uff0c\u8840\u6e05\u4e2dTNF-\u03b1\u3001IL-4\u3001IL-6\u6c34\u5e73\u5206\u522b\u4e3a261.38 pg\/mL\u300184.52 pg\/mL\u300180.37 pg\/mL\u3002<\/p>\n

      \u9ad8\u5242\u91cf\u795b\u98ce\u6da6\u71e5\u6b62\u75d2\u6ebb\u6e0d\u65b9\u6cbb\u7597\u540eTNF-\u03b1\u3001IL-4\u3001IL-6\u6c34\u5e73\u964d\u4f4e\u4e3a154.68 pg\/mL\u300173.15 pg\/mL\u300157.03 pg\/mL\uff08\u56fe3\uff09\u3002\u6b64\u5916\uff0c\u795b\u98ce\u6da6\u71e5\u6b62\u75d2\u6ebb\u6e0d\u65b9\u4e5f\u663e\u8457\u6291\u5236TNF-\u03b1\u3001IL-4\u3001IL-6\u7684\u57fa\u56e0\u3002<\/p>\n<\/p>\n

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        TLR4\uff08Toll\u6837\u53d7\u4f534\uff09\u548cNF-\u03baB\uff08\u6838\u56e0\u5b50\u03baB\uff09\u662f\u514d\u75ab\u7cfb\u7edf\u4e2d\u4e24\u4e2a\u91cd\u8981\u7684\u5206\u5b50\u662fToll\u6837\u53d7\u4f53\u5bb6\u65cf\u7684\u4e00\u5458\uff0c\u4e3b\u8981\u5728\u514d\u75ab\u7cfb\u7edf\u7684\u7ec6\u80de\u5982\u5de8\u566c\u7ec6\u80de\u548c\u6811\u7a81\u7ec6\u80de\u8868\u9762\u8868\u8fbe\u3002\u4f5c\u4e3a\u75c5\u539f\u4f53\u76f8\u5173\u5206\u5b50\u6a21\u5f0f\uff08PAMPs\uff09\u7684\u8bc6\u522b\u53d7\u4f53\uff0c\u53c2\u4e0e\u5148\u5929\u514d\u75ab\u53cd\u5e94.\u5f53TLR4\u8bc6\u522b\u5230\u75c5\u539f\u4f53\u4fe1\u53f7\u540e\uff0c\u4f1a\u5f15\u8d77\u4e00\u7cfb\u5217\u4fe1\u53f7\u4f20\u5bfc\u4e8b\u4ef6\uff0c\u5bfc\u81f4NF-\u03baB\u7684\u6d3b\u5316\u3002\u7279\u5e94\u6027\u76ae\u708e\u4e2dTLR4\/NF-\u03baB\u4fe1\u53f7\u901a\u8def\u8fc7\u5ea6\u6d3b\u5316\uff0c\u5bfc\u81f4\u708e\u75c7\u53cd\u5e94\u7684\u6301\u7eed\u548c\u52a0\u5267\u3002<\/p>\n

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          1.\u795b\u98ce\u6da6\u71e5\u6b62\u75d2\u6ebb\u6e0d\u65b9\u6539\u5584\u7279\u5e94\u6027\u76ae\u708e\u5c0f\u9f20\u76ae\u80a4\u75c7\u72b6\u3001\u7f13\u89e3\u75c5\u7406\u53d8\u5316<\/p>\n

          2.\u795b\u98ce\u6da6\u71e5\u6b62\u75d2\u6ebb\u6e0d\u65b9\u6291\u5236TNF-\u03b1\u3001IL-4\u3001IL-6<\/p>\n

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    \u53c2\u8003\u6587\u732e<\/p>\n

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    \u91d1\u857e,\u738b\u4e07\u6625. \u795b\u98ce\u6da6\u71e5\u6b62\u75d2\u6ebb\u6e0d\u65b9\u5bf9\u6162\u6027\u6e7f\u75b9\u6a21\u578b\u5c0f\u9f20\u76ae\u80a4\u635f\u4f24\u53caTLR4\/NF-\u03baB\u901a\u8def\u7684\u5f71\u54cd [J]. \u65f6\u73cd\u56fd\u533b\u56fd\u836f, 2024, 35 (05): 1110-1113<\/p>\n<\/li>\n","protected":false},"excerpt":{"rendered":"

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