\u91cd\u5ea6\u54ee\u5598\u662f\u54ee\u5598\u60a3\u8005\u81f4\u6b8b\u3001\u81f4\u6b7b\u7684\u4e3b\u8981\u539f\u56e0\uff0c\u5177\u6709\u9ad8\u5ea6\u7684\u75be\u75c5\u672a\u6765\u98ce\u9669\uff0c\u4e5f\u9020\u6210\u4e86\u4e25\u91cd\u7684\u793e\u4f1a\u7ecf\u6d4e\u8d1f\u62c5\u3002\u5982\u4f55\u5bf9\u91cd\u5ea6\u54ee\u5598\u60a3\u8005\u8fdb\u884c\u6b63\u786e\u7684\u8bca\u65ad\u548c\u8bc4\u4f30\uff0c\u5982\u4f55\u8fdb\u884c\u6cbb\u7597\u9009\u62e9\uff0c\u4ecd\u7136\u662f\u4e34\u5e8a\u5b9e\u8df5\u5b58\u5728\u7684\u56f0\u60d1\u4e0e\u6311\u6218\u3002<\/p>\n
\u672c\u4e13\u5bb6\u5171\u8bc6\u5728 2017 \u5e74\u53d1\u8868\u7684\u300a\u91cd\u75c7\u54ee\u5598\u8bca\u65ad\u4e0e\u5904\u7406\u4e2d\u56fd\u4e13\u5bb6\u5171\u8bc6\u300b\u57fa\u7840\u4e0a\uff0c\u7ed3\u5408\u6700\u65b0\u56fd\u5185\u5916\u7814\u7a76\u8fdb\u5c55\uff0c\u56f4\u7ed5\u91cd\u5ea6\u54ee\u5598\u7684\u5b9a\u4e49\u3001\u53d1\u75c5\u673a\u5236\u3001\u8bca\u65ad\u4e0e\u8bc4\u4f30\u3001\u6cbb\u7597\u7b49\u65b9\u9762\u8fdb\u884c\u4e86\u66f4\u65b0\uff0c\u7279\u522b\u662f\u5bf9 2 \u578b\u708e\u75c7\u751f\u7269\u5236\u5242\u7684\u6cbb\u7597\u63a8\u8350\uff0c\u4e3a\u91cd\u5ea6\u54ee\u5598\u7684\u4e2a\u4f53\u5316\u8bca\u7597\u63d0\u4f9b\u53c2\u8003\u3002<\/p>\n
\u5b9a\u4e49<\/p>\n
\u957f\u671f\u4ee5\u6765\uff0c\u56fd\u5185\u5916\u5bf9\u91cd\u5ea6\u54ee\u5598\u7684\u5b9a\u4e49\u5c1a\u4e0d\u7edf\u4e00\u3002<\/p>\n
\u672c\u5171\u8bc6\u53c2\u7167 2023 \u66f4\u65b0\u7684\u5168\u7403\u54ee\u5598\u9632\u6cbb\u521b\u8bae\uff08GINA\uff09\u63d0\u51fa\u7684\u610f\u89c1\uff0c\u5c06\u91cd\u5ea6\u54ee\u5598\u5b9a\u4e49\u4e3a\uff1a\u5728\u6392\u9664\u60a3\u8005\u4f9d\u4ece\u6027\u53ca\u836f\u7269\u5438\u5165\u6280\u672f\u56e0\u7d20\u5916\uff0c\u89c4\u5f8b\u8054\u5408\u5438\u5165\u9ad8\u5242\u91cf\u7cd6\u76ae\u8d28\u6fc0\u7d20\u548c\u957f\u6548 \u03b22 \u53d7\u4f53\u6fc0\u52a8\u5242\uff08LABA\uff09\u6cbb\u7597 3 \u4e2a\u6708\u6216\u4ee5\u4e0a\uff0c\u5e76\u5728\u5145\u5206\u7ba1\u7406\u5f71\u54cd\u54ee\u5598\u63a7\u5236\u5404\u79cd\u56e0\u7d20\u540e\uff0c\u4e0d\u80fd\u8fbe\u5230\u54ee\u5598\u63a7\u5236\u7684\u60a3\u8005\uff0c\u6216\u4e0a\u8ff0\u6cbb\u7597\u964d\u7ea7\u540e\u5931\u53bb\u63a7\u5236\u7684\u60a3\u8005\u3002<\/p>\n
\u91cd\u5ea6\u54ee\u5598\u7684\u8bca\u65ad\u548c\u8bc4\u4f30\u6d41\u7a0b<\/p>\n
\u91cd\u5ea6\u54ee\u5598\u5360\u6574\u4e2a\u54ee\u5598\u7fa4\u4f53\u7684\u6bd4\u4f8b\u4e3a 5%~10%\uff0c\u4f46\u4e34\u5e8a\u6cbb\u7597\u548c\u7ba1\u7406\u975e\u5e38\u68d8\u624b\uff0c\u5bf9\u60a3\u8005\u4e2a\u4eba\u3001\u5bb6\u5ead\u3001\u533b\u5e08\u548c\u533b\u7597\u536b\u751f\u8d44\u6e90\u5747\u6784\u6210\u6c89\u91cd\u7684\u8d1f\u62c5\uff0c\u56e0\u6b64\u8bca\u65ad\u91cd\u5ea6\u54ee\u5598\u5fc5\u987b\u614e\u4e4b\u53c8\u614e\uff0c\u5207\u52ff\u8f7b\u7387\u7ed9\u54ee\u5598\u60a3\u8005\u8d34\u4e0a\u300c\u91cd\u5ea6\u54ee\u5598\u300d\u7684\u6807\u7b7e\u3002<\/p>\n
\u54ee\u5598\u60a3\u8005\u5bf9\u75c7\u72b6\u7684\u611f\u77e5\u80fd\u529b\u3001\u4f9d\u4ece\u6027\u3001\u7528\u836f\u6280\u672f\u7b49\u5dee\u5f02\u5f88\u5927\uff0c\u5f71\u54cd\u54ee\u5598\u63a7\u5236\u7684\u56e0\u7d20\u4f17\u591a\uff0c\u5728\u91cd\u5ea6\u54ee\u5598\u4e2d\u5c24\u5176\u7a81\u51fa\uff0c\u975e\u4e13\u79d1\u533b\u5e08\u7279\u522b\u662f\u57fa\u5c42\u533b\u5e08\u5bb9\u6613\u51fa\u73b0\u5224\u65ad\u4e0a\u7684\u504f\u5dee\uff0c\u56e0\u6b64\u91cd\u5ea6\u54ee\u5598\u539f\u5219\u4e0a\u5e94\u8be5\u7531\u54ee\u5598\u4e13\u79d1\u533b\u5e08\u8fdb\u884c\u8be6\u7ec6\u7684\u8bca\u65ad\u548c\u5168\u9762\u7684\u8bc4\u4f30\uff0c\u5e76\u8fdb\u884c\u6b63\u89c4\u7684\u6cbb\u7597\u548c\u89c4\u5f8b\u7684\u968f\u8bbf\u3002<\/p>\n
\u6ce8\uff1aICS \u4e3a\u5438\u5165\u6027\u7cd6\u76ae\u8d28\u6fc0\u7d20\uff1bLABA \u4e3a\u957f\u6548 \u03b22 \u53d7\u4f53\u6fc0\u52a8\u5242\uff1b\u6162\u963b\u80ba\u4e3a\u6162\u6027\u963b\u585e\u6027\u80ba\u75be\u75c5\uff1bABPA \u4e3a\u53d8\u5e94\u6027\u652f\u6c14\u7ba1\u80ba\u66f2\u9709\u83cc\u75c5\uff1bEGPA \u4e3a\u55dc\u9178\u6027\u8089\u82bd\u80bf\u6027\u591a\u8840\u7ba1\u708e\uff1bNSAID \u4e3a\u975e\u753e\u4f53\u6297\u708e\u836f\uff1bACEI \u4e3a\u8840\u7ba1\u7d27\u5f20\u7d20\u8f6c\u5316\u9176\u6291\u5236\u5242<\/p>\n
\u5e38\u89c4\u836f\u7269\u6cbb\u7597<\/p>\n
1. \u7cd6\u76ae\u8d28\u6fc0\u7d20<\/p>\n
\u91cd\u5ea6\u54ee\u5598\u60a3\u8005\u5e38\u9700\u8981\u7ed9\u4e88\u9ad8\u5242\u91cf ICS \u6216 ICS \u8054\u5408\u53e3\u670d\u7cd6\u76ae\u8d28\u6fc0\u7d20\uff08OCS\uff09\u6cbb\u7597\u3002<\/p>\n
\uff081\uff09ICS<\/p>\n
\u4e00\u822c\u800c\u8a00\uff0c\u54ee\u5598\u60a3\u8005 ICS \u5242\u91cf\u8d8a\u5927\uff0c\u6297\u708e\u4f5c\u7528\u8d8a\u5f3a\uff0c\u4f46\u9700\u6ce8\u610f\u8fc7\u9ad8\u7684 ICS \u5242\u91cf\u4e0d\u80fd\u989d\u5916\u83b7\u76ca\uff0c\u751a\u81f3\u5e26\u6765 ICS \u76f8\u5173\u4e0d\u826f\u53cd\u5e94\u3002\u6839\u636e 2023 \u7248 GINA\uff0c\u5e38\u7528\u9ad8\u5242\u91cf ICS \u7684\u5b9a\u4e49\u5982\u8868\u6240\u793a\u3002<\/p>\n
\u57fa\u4e8e\u4e0d\u540c\u5e74\u9f84\u6bb5\u91cd\u5ea6\u54ee\u5598\u60a3\u8005\u6bcf\u65e5\u9ad8\u5242\u91cf ICS \u7684\u503c<\/p>\n
\u6ce8\uff1aICS \u4e3a\u5438\u5165\u6027\u7cd6\u76ae\u8d28\u6fc0\u7d20\uff1bpMDI \u4e3a\u538b\u529b\u5b9a\u91cf\u5438\u5165\u5242\uff1bHFA \u4e3a\u6c22\u6c1f\u70f7\u70c3\u63a8\u8fdb\u5242\uff1bDPI \u4e3a\u5e72\u7c89\u5438\u5165\u5668\uff1b\u201c-\u201d \u4e3a\u4e0d\u9002\u7528<\/p>\n
\uff082\uff09OCS<\/p>\n
\u5bf9\u4e8e\u5df2\u7ecf\u4f7f\u7528\u9ad8\u5242\u91cf ICS LABA \u7ef4\u6301\u6cbb\u7597\uff0c\u75c7\u72b6\u4ecd\u672a\u63a7\u5236\u7684\u91cd\u5ea6\u54ee\u5598\u60a3\u8005\u53ef\u4ee5\u52a0\u7528 OCS \u6cbb\u7597\uff0c\u4e00\u822c\u9009\u7528\u534a\u8870\u671f\u8f83\u77ed\u7684\u6fc0\u7d20\uff08\u5982\u6cfc\u5c3c\u677e\u7b49\uff09\uff0c\u91c7\u53d6\u5c0f\u5242\u91cf\u3001\u77ed\u7597\u7a0b\u65b9\u6848\uff0c\u4e0d\u63a8\u8350\u957f\u671f\u4f7f\u7528\uff0c\u957f\u671f\u4f4e\u5242\u91cf OCS \u4ec5\u5728\u65e0\u5176\u4ed6\u66ff\u4ee3\u65b9\u6848\u65f6\u4f5c\u4e3a\u6700\u540e\u7684\u9009\u62e9\u3002<\/p>\n
\uff083\uff09\u808c\u5185\u6ce8\u5c04\u957f\u6548\u6fc0\u7d20<\/p>\n
\u808c\u5185\u6ce8\u5c04\u957f\u6548\u6fc0\u7d20\u66f2\u5b89\u897f\u9f99 3 mL \u53ef\u7528\u4e8e\u6cbb\u7597\u6fc0\u7d20\u4e0d\u654f\u611f\u6027\u91cd\u5ea6\u54ee\u5598\u60a3\u8005\u3002\u4f46\u662f\uff0c\u9274\u4e8e\u5176\u5bf9\u4e8e\u80be\u4e0a\u817a\u76ae\u8d28\u529f\u80fd\u7684\u6291\u5236\u548c\u4f7f\u60a3\u8005\u6613\u4e8e\u4ea7\u751f\u4f9d\u8d56\u6027\u7684\u4e0d\u826f\u53cd\u5e94\uff0c\u4e0d\u63a8\u8350\u4f7f\u7528\u3002 <\/p>\n
2. \u03b22 \u53d7\u4f53\u6fc0\u52a8\u5242<\/p>\n
\u03b22 \u53d7\u4f53\u6fc0\u52a8\u5242\u5e94\u4e0e ICS \u8054\u5408\u4f7f\u7528\uff0c\u5355\u72ec\u5e94\u7528\u8fc7\u591a \u03b22 \u53d7\u4f53\u6fc0\u52a8\u5242\u4e0e\u54ee\u5598\u6025\u6027\u52a0\u91cd\u53ca\u6b7b\u4ea1\u98ce\u9669\u589e\u52a0\u6709\u5173\u3002\u6301\u7eed\u9759\u8109\u6ef4\u6ce8\u7279\u5e03\u4ed6\u6797\u6709\u52a9\u4e8e\u51cf\u5c11\u91cd\u5ea6\u54ee\u5598\u7684\u53d1\u4f5c\u548c\u4f4f\u9662\u6b21\u6570\uff0c\u4f46\u56e0\u5168\u8eab\u4e0d\u826f\u53cd\u5e94\u53d1\u751f\u7387\u8f83\u9ad8\uff0c\u4e0d\u63a8\u8350\u4f7f\u7528\u3002<\/p>\n
3. ICS LABA \u590d\u5408\u5236\u5242<\/p>\n
\u91cd\u5ea6\u54ee\u5598\u7684\u6cbb\u7597\u4e2d\uff0cLABA \u8054\u5408 ICS \u7684\u590d\u5408\u5236\u5242\u7684\u7597\u6548\u660e\u663e\u4f18\u4e8e\u5355\u836f\uff0c\u5728\u8054\u5408 LABA \u7684\u57fa\u7840\u4e0a\u9010\u6b65\u589e\u52a0 ICS \u5242\u91cf\u53ef\u80fd\u4f1a\u8fdb\u4e00\u6b65\u6539\u5584\u54ee\u5598\u7684\u63a7\u5236\u3002\u76ee\u524d\u5728\u6211\u56fd\u4e34\u5e8a\u4e0a\u5e94\u7528\u7684 ICS LABA \u590d\u5408\u5236\u5242\u6709\u5e03\u5730\u5948\u5fb7\/\u798f\u83ab\u7279\u7f57\u3001\u6c1f\u66ff\u5361\u677e\/\u6c99\u7f8e\u7279\u7f57\u3001\u4e19\u9178\u500d\u6c2f\u7c73\u677e\/\u798f\u83ab\u7279\u7f57\u548c\u7ce0\u9178\u6c1f\u66ff\u5361\u677e\/\u7ef4\u5170\u7279\u7f57\u3002<\/p>\n
4. \u6297\u80c6\u78b1\u80fd\u836f\u7269<\/p>\n
\u77ed\u6548\u6297\u80c6\u78b1\u836f\u5f02\u4e19\u6258\u6eb4\u94f5\u6c14\u96fe\u5242\u53ef\u51cf\u8f7b\u91cd\u5ea6\u54ee\u5598\u60a3\u8005\u7684\u6c14\u5598\u75c7\u72b6\uff0c\u5e76\u51cf\u5c11 \u03b22 \u53d7\u4f53\u6fc0\u52a8\u5242\u8fc7\u91cf\u4f7f\u7528\u3002\u8bb8\u591a\u91cd\u5ea6\u54ee\u5598\u60a3\u8005\u5c3d\u7ba1\u63a5\u53d7 ICS LABA \u6cbb\u7597\uff0c\u4ecd\u5b58\u5728\u6301\u7eed\u7684\u6c14\u6d41\u53d7\u9650\u3002\u5bf9\u4e8e\u5df2\u7ecf\u4f7f\u7528\u4e2d\u2011\u9ad8\u5242\u91cf ICS \u8054\u5408 LABA \u7684\u91cd\u5ea6\u54ee\u5598\u60a3\u8005\uff0c\u6dfb\u52a0 LAMA \u567b\u6258\u6eb4\u94f5\u53ef\u51cf\u5c11\u6c14\u4f53\u9677\u95ed\uff0c\u51cf\u5c11\u6025\u6027\u52a0\u91cd\u9891\u7387\u548c\u6539\u5584\u80ba\u529f\u80fd\u3002<\/p>\n
5. ICS LABA LAMA \u590d\u5408\u5236\u5242<\/p>\n
\u5bf9\u5e38\u89c4 ICS LABA \u6cbb\u7597\u63a7\u5236\u4e0d\u4f73\u7684\u60a3\u8005\u53ef\u9009\u62e9 ICS LABA LAMA \u4e09\u8054\u5236\u5242\uff0c\u5305\u62ec\u7ce0\u9178\u83ab\u7c73\u677e \u831a\u8fbe\u7279\u7f57 \u683c\u9686\u6eb4\u94f5\u7c89\u96fe\u5242\u3001\u7ce0\u9178\u6c1f\u66ff\u5361\u677e \u7ef4\u5170\u7279\u7f57 \u4e4c\u7f8e\u6eb4\u94f5\u7c89\u96fe\u5242\u3001\u5e03\u5730\u5948\u5fb7 \u798f\u83ab\u7279\u7f57 \u683c\u9686\u6eb4\u94f5\u6c14\u96fe\u5242\u548c\u4e19\u9178\u500d\u6c2f\u7c73\u677e \u5bcc\u9a6c\u9178\u798f\u83ab\u7279\u7f57 \u683c\u9686\u6eb4\u94f5\u6c14\u96fe\u5242\u3002\u76ee\u524d\u6211\u56fd\u7ce0\u9178\u83ab\u7c73\u677e \u831a\u8fbe\u7279\u7f57 \u683c\u9686\u6eb4\u94f5\u7c89\u96fe\u5242\u5df2\u83b7\u6279\u7528\u4e8e\u54ee\u5598\u6cbb\u7597\u3002<\/p>\n
6. \u8336\u78b1<\/p>\n
\u5bf9\u4e8e\u91cd\u5ea6\u54ee\u5598\u60a3\u8005\uff0c\u8336\u78b1\u8054\u5408 ICS \u6cbb\u7597\u6709\u52a9\u4e8e\u54ee\u5598\u75c7\u72b6\u7684\u63a7\u5236\u3002\u5bf9\u4e8e\u5438\u70df\u4f34\u6fc0\u7d20\u4e0d\u654f\u611f\u7684\u54ee\u5598\u60a3\u8005\uff0c\u8336\u78b1\u8054\u5408\u4f4e\u5242\u91cf ICS \u53ef\u660e\u663e\u63d0\u9ad8\u547c\u6c14\u5cf0\u6d41\u901f\u548c\u54ee\u5598\u63a7\u5236\u7a0b\u5ea6\u3002\u4f46\u8be5\u836f\u5728\u91cd\u5ea6\u54ee\u5598\u4e2d\u7684\u5730\u4f4d\u5c1a\u4e0d\u786e\u5b9a\u3002<\/p>\n
7. \u767d\u4e09\u70ef\u8c03\u8282\u5242<\/p>\n
\u591a\u9879\u5173\u4e8e\u672a\u4f7f\u7528 LABA \u7684\u4e2d\u91cd\u5ea6\u54ee\u5598\u60a3\u8005\u4e2d\u7684\u7814\u7a76\u7ed3\u679c\u663e\u793a\uff0cICS \u8054\u5408\u767d\u4e09\u70ef\u8c03\u8282\u5242\u5bf9\u6539\u5584\u80ba\u529f\u80fd\u5177\u6709\u4e00\u5b9a\u7597\u6548\u3002<\/p>\n
\u751f\u7269\u5236\u5242<\/p>\n
\u8fd1\u5e74\u5df2\u7ecf\u6709\u56db\u7c7b\u7528\u4e8e\u54ee\u5598\u6cbb\u7597\u7684\u751f\u7269\u5236\u5242\u83b7\u6279\u4e0a\u5e02\uff0c\u5206\u522b\u662f\u6297 IgE\u3001\u6297 IL\u20115\/IL\u20115 \u53d7\u4f53\uff08IL\u20115R\uff09\uff0c\u6297 IL\u20114 \u53d7\u4f53\uff08IL\u20114R\uff09\u548c\u6297 TSLP \u5355\u6297\uff0c\u8fd9\u4e9b\u751f\u7269\u5236\u5242\u4e3b\u8981\u9488\u5bf9 2 \u578b\u91cd\u5ea6\u54ee\u5598\u3002<\/p>\n
GINA \u63a8\u8350\u8fd9\u4e9b\u751f\u7269\u5236\u5242\u4f5c\u4e3a\u9644\u52a0\u6cbb\u7597\u7528\u4e8e\u7ecf\u7b2c 4 \u7ea7\u6cbb\u7597\u4ecd\u4e0d\u80fd\u63a7\u5236\u7684\u91cd\u5ea6\u54ee\u5598\u3002\u5728\u6211\u56fd\u4e5f\u5df2\u7ecf\u6709\u5965\u9a6c\u73e0\u5355\u6297\u3001\u5ea6\u666e\u5229\u5c24\u5355\u6297\u548c\u7f8e\u6cca\u5229\u73e0\u5355\u6297\u4e0a\u5e02\u3002<\/p>\n
1. \u751f\u7269\u5236\u5242\u7684\u79cd\u7c7b<\/p>\n
\u7528\u4e8e\u6cbb\u7597\u91cd\u5ea6\u54ee\u5598\u7684\u751f\u7269\u5236\u5242\u7684\u76f8\u5173\u60c5\u51b5<\/p>\n
\u6ce8\uff1aIL \u4e3a\u767d\u7ec6\u80de\u4ecb\u7d20\uff1bTSLP \u4e3a\u80f8\u817a\u57fa\u8d28\u6dcb\u5df4\u7ec6\u80de\u751f\u6210\u7d20\uff1bEGPA \u4e3a\u55dc\u9178\u6027\u8089\u82bd\u80bf\u6027\u591a\u8840\u7ba1\u708e\uff1bOCS \u4e3a\u53e3\u670d\u7cd6\u76ae\u8d28\u6fc0\u7d20\uff1bFeNO \u4e3a\u547c\u51fa\u6c14\u4e00\u6c27\u5316\u6c2e<\/p>\n
2. \u4e0d\u540c\u751f\u7269\u5236\u5242\u7684\u9009\u62e9<\/p>\n
\u7531\u4e8e\u76ee\u524d\u5c1a\u6ca1\u6709\u4e0d\u540c\u751f\u7269\u5236\u5242\u4e4b\u95f4\u7684\u5934\u5bf9\u5934\u6bd4\u8f83\u7814\u7a76\uff0c\u56e0\u6b64\u5c1a\u96be\u4ee5\u8bc4\u4ef7\u54ea\u4e00\u79cd\u751f\u7269\u5236\u5242\u66f4\u597d\u3002\u603b\u4f53\u800c\u8a00\uff0c\u76ee\u524d\u4e0a\u5e02\u7684\u751f\u7269\u5236\u5242\u90fd\u53ef\u4ee5\u51cf\u5c11\u54ee\u5598\u6025\u6027\u53d1\u4f5c\u7387\uff0c\u51cf\u5c11\u7387\u4e3a 30%~70%\u3002<\/p>\n
\u57fa\u4e8e\u8fc7\u654f\u6027\u54ee\u5598\u53d1\u75c5\u7387\u8f83\u9ad8\uff0c\u4ee5\u53ca\u836f\u7269\u53ef\u53ca\u6027\u3001\u533b\u4fdd\u9002\u5e94\u8bc1\u7b49\u56e0\u7d20\uff0c\u5965\u9a6c\u73e0\u5355\u6297\u5bf9 IgE \u4ecb\u5bfc\u7684\u8fc7\u654f\u6027\u54ee\u5598\u53ef\u4ee5\u8003\u8651\u4f5c\u4e3a\u9996\u9009\u3002<\/p>\n
\u7531\u4e8e IL\u20115 \u7684\u4e3b\u8981\u751f\u7269\u5b66\u4f5c\u7528\u9650\u4e8e EOS\uff0c\u56e0\u6b64\uff0c\u6297 IL\u20115\/IL\u20115R \u5355\u6297\u5bf9\u55dc\u9178\u7c92\u7ec6\u80de\u6027\u91cd\u5ea6\u54ee\u5598\u66f4\u4e3a\u6070\u5f53\uff0c\u5c24\u5176\u662f\u5408\u5e76 EOS \u589e\u591a\u75be\u75c5\uff0c\u5982 EOS \u6027\u9f3b\u606f\u8089\u7b49\u60a3\u8005\u5c24\u4e3a\u9002\u5408\u3002<\/p>\n
\u7531\u4e8e\u6297 IL\u20114R\u03b1 \u5355\u6297\u5177\u6709\u540c\u65f6\u963b\u65ad IL\u20114 \u548c IL\u201113 \u53cc\u4fe1\u53f7\u7684\u4f5c\u7528\uff0c\u56e0\u6b64\u6297 IL\u20114R\u03b1 \u5355\u6297\u7684\u6297\u708e\u4f5c\u7528\u66f4\u4e3a\u5e7f\u6cdb\uff0c\u5305\u62ec\u4e86\u5bf9 Th2 \u7ec6\u80de\u6d3b\u5316\u3001IgE \u751f\u6210\u3001\u6c14\u9053\u676f\u72b6\u7ec6\u80de\u589e\u751f\u3001\u9ecf\u6db2\u5206\u6ccc\u548c\u6c14\u9053\u9ad8\u53cd\u5e94\u6027\u7b49\u3002<\/p>\n
\u7279\u6cfd\u9c81\u5355\u6297\u5219\u662f\u76ee\u524d\u552f\u4e00\u83b7\u6279\u5bf9\u975e 2 \u578b\u54ee\u5598\u4e5f\u53ef\u4ee5\u4f7f\u7528\u7684\u751f\u7269\u5236\u5242\uff0c\u4e0d\u7ba1 EOS \u6c34\u5e73\u5982\u4f55\uff0c\u90fd\u6709\u83b7\u76ca\uff0c\u4f46 EOS \u6c34\u5e73\u66f4\u9ad8\u7684\u60a3\u8005\u83b7\u76ca\u66f4\u663e\u8457\u3002<\/p>\n
\u4ee5\u4e0a\u4ecb\u7ecd\u7684\u56db\u7c7b\u751f\u7269\u5236\u5242\uff0c\u867d\u7136\u5bf9\u708e\u75c7\u73af\u8282\u7684\u9776\u70b9\u4e0d\u540c\uff0c\u4f46\u4e3b\u8981\u90fd\u662f\u9488\u5bf9 2 \u578b\u54ee\u5598\uff0c2 \u578b\u708e\u75c7\u6807\u5fd7\u7269\u5982\u8840 EOS\u3001FeNO \u6c34\u5e73\u9ad8\u7684\u60a3\u8005\u6cbb\u7597\u6548\u679c\u66f4\u597d\u3002<\/p>\n
3. \u6cbb\u7597\u540e\u76d1\u6d4b<\/p>\n
\u5728\u542f\u52a8\u751f\u7269\u5236\u5242\u6cbb\u7597\u540e\u7684 3~4 \u4e2a\u6708\u9700\u8981\u8fdb\u884c\u6cbb\u7597\u53cd\u5e94\u7684\u8bc4\u4f30\u3002\u8bc4\u4f30\u7684\u5185\u5bb9\u4e3a\uff1a<\/p>\n
\uff081\uff09\u54ee\u5598\u63a7\u5236\u60c5\u51b5<\/p>\n
\u75c7\u72b6\u8bc4\u5206\uff0c\u6025\u6027\u53d1\u4f5c\u60c5\u51b5\u3001OCS \u4f7f\u7528\uff0c\u80ba\u529f\u80fd\u6d4b\u8bd5\u7b49\u3002<\/p>\n
\uff082\uff092 \u578b\u5171\u75c5\u7684\u8bc4\u4f30<\/p>\n
\u9f3b\u606f\u8089\u3001\u8fc7\u654f\u6027\u76ae\u708e\u7b49\u3002<\/p>\n
\uff083\uff09\u6cbb\u7597\u7528\u836f<\/p>\n
\u57fa\u7840\u6cbb\u7597\u7528\u836f\u7684\u60c5\u51b5\uff08ICS\/LABA \u7b49\uff09\uff0cOCS \u7684\u4f7f\u7528\uff0c\u836f\u7269\u4e0d\u826f\u53cd\u5e94\uff0c\u60a3\u8005\u5bf9\u836f\u7269\u7ecf\u6d4e\u8d1f\u62c5\u7684\u627f\u53d7\u80fd\u529b\u3002<\/p>\n
\uff084\uff09\u60a3\u8005\u5bf9\u6cbb\u7597\u7684\u6ee1\u610f\u5ea6<\/p>\n
\u5bf9\u6cbb\u7597\u53cd\u5e94\u826f\u597d\u7684\u60a3\u8005\u9996\u5148\u8003\u8651\u51cf\u5c11\u6216\u505c\u7528 OCS\uff0c\u7136\u540e\u505c\u6b62\u5176\u4ed6\u9644\u52a0\u6cbb\u7597\u836f\u7269\uff0c\u6700\u540e\u624d\u8003\u8651\u51cf\u5c11\u5438\u5165\u836f\u7269\u5242\u91cf\uff0c\u4f7f\u7528\u4e2d\u7b49\u5242\u91cf ICS\u2011LABA \u7684\u590d\u5408\u5236\u5242\u8fdb\u884c\u7ef4\u6301\u6cbb\u7597\uff0c\u4f46\u4e0d\u5e94\u505c\u836f\u3002<\/p>\n
\u751f\u7269\u5236\u5242\u6cbb\u7597\u81f3\u5c11\u7ef4\u6301 12 \u4e2a\u6708\uff0c\u6709\u7814\u7a76\u53d1\u73b0\uff0c\u505c\u7528\u751f\u7269\u5236\u5242\u53ef\u80fd\u518d\u6b21\u53d1\u751f\u54ee\u5598\u52a0\u91cd\u3002<\/p>\n
\u4f46\u662f\u7ecf\u8bc4\u4f30\u5bf9\u751f\u7269\u5236\u5242\u6cbb\u7597\u53cd\u5e94\u4e0d\u4f73\u7684\u60a3\u8005\uff0c\u5e94\u505c\u7528\u751f\u7269\u5236\u5242\u6cbb\u7597\uff0c\u91cd\u65b0\u8bc4\u4f30\u60a3\u8005\u75c5\u60c5\u548c\u6cbb\u7597\u60c5\u51b5\uff0c\u8003\u8651\u5176\u4ed6\u9644\u52a0\u7684\u6cbb\u7597\u65b9\u6cd5\u3002<\/p>\n
\u5176\u4ed6\u836f\u7269<\/p>\n
\u4e3b\u8981\u6709\u5927\u73af\u5185\u916f\u7c7b\u6297\u83cc\u836f\u7269\u3001\u6297\u771f\u83cc\u836f\u7269\u3001\u514d\u75ab\u6291\u5236\u5242\u548c\u6297\u4ee3\u8c22\u836f\u7269\u3002<\/p>\n
1. \u5927\u73af\u5185\u916f\u7c7b\u6297\u83cc\u836f\u7269<\/p>\n
\u6709\u7814\u7a76\u62a5\u544a\uff0c\u53e3\u670d\u5c0f\u5242\u91cf\u5927\u73af\u5185\u916f\u7c7b\u6297\u83cc\u836f\u7269\uff08\u5982\u963f\u5947\u9709\u7d20\u3001\u514b\u62c9\u9709\u7d20\u7b49\uff09\u53ef\u51cf\u8f7b\u4e2d\u6027\u7c92\u7ec6\u80de\u4e3a\u4e3b\u7684\u6c14\u9053\u708e\u75c7\uff0c\u964d\u4f4e\u6c14\u9053\u9ad8\u53cd\u5e94\u6027\uff0c\u6709\u52a9\u4e8e\u91cd\u5ea6\u54ee\u5598\u7684\u6cbb\u7597\u3002<\/p>\n
\u4f46\u957f\u671f\u4f7f\u7528\u5927\u73af\u5185\u916f\u7c7b\u836f\u7269\u53ef\u80fd\u5bfc\u81f4\u8179\u6cfb\u3001QT \u95f4\u671f\u5ef6\u957f\u3001\u542c\u529b\u51cf\u9000\u7b49\u4e0d\u826f\u53cd\u5e94\u53ca\u8010\u836f\u7684\u4ea7\u751f\uff0c\u4f7f\u7528\u524d\u9700\u8bf7\u4e13\u79d1\u533b\u5e08\u8bc4\u4f30\uff0c\u5e76\u5728\u7528\u836f\u8fc7\u7a0b\u4e2d\u52a0\u5f3a\u76d1\u6d4b\u3002 <\/p>\n
2. \u6297\u771f\u83cc\u836f\u7269<\/p>\n
\u6297\u771f\u83cc\u836f\u7269\u4e3b\u8981\u7528\u4e8e\u4f34\u6709 ABPA \u4e14\u53cd\u590d\u53d1\u4f5c\u7684\u91cd\u5ea6\u54ee\u5598\u60a3\u8005\uff0c\u53ef\u51cf\u5c11\u6025\u6027\u53d1\u4f5c\u98ce\u9669\u548c\u6539\u5584\u75c7\u72b6\uff0c\u5e38\u7528\u6297\u771f\u83cc\u836f\u7269\u5305\u62ec\u4f0f\u7acb\u5eb7\u5511\u548c\u4f0a\u66f2\u5eb7\u5511\u3002<\/p>\n
\u5bf9\u4e8e\u76ae\u80a4\u70b9\u523a\u8bd5\u9a8c\u6216\u8840\u6e05\u771f\u83cc\u7279\u5f02 IgE \u9633\u6027\uff0c\u4f46\u4e0d\u5408\u5e76 ABPA \u7684\u91cd\u5ea6\u54ee\u5598\u60a3\u8005\u4e0d\u63a8\u8350\u4f7f\u7528\u6297\u771f\u83cc\u836f\uff0c\u4e3b\u8981\u8003\u8651\u5230\u6297\u771f\u83cc\u836f\u4e0e\u5176\u4ed6\u836f\u7269\u4e4b\u95f4\u7684\u76f8\u4e92\u4f5c\u7528\u3001\u836f\u7269\u4e0d\u826f\u53cd\u5e94\u3001\u533b\u7597\u8d39\u7528\u7684\u589e\u52a0\u4ee5\u53ca\u5176\u4e34\u5e8a\u83b7\u76ca\u7684\u4e0d\u786e\u5b9a\u6027\u3002<\/p>\n
3. \u514d\u75ab\u6291\u5236\u5242\u548c\u6297\u4ee3\u8c22\u836f\u7269<\/p>\n
\u5728\u4e00\u9879\u9488\u5bf9\u91cd\u75c7\u55dc\u9178\u7c92\u7ec6\u80de\u6027\u54ee\u5598\u7814\u7a76\u4e2d\uff0c15%\uff089\/61\uff09\u7684\u60a3\u8005\u5bf9\u7532\u6c28\u8776\u5464\u6cbb\u7597\u6709\u53cd\u5e94\uff0c\u53ef\u4ee5\u663e\u8457\u51cf\u5c11 OCS \u7684\u5242\u91cf\uff0c\u5e73\u5747\u4ece 15 mg\/d \u964d\u5230 6.25 mg\/d\uff0c\u4f46\u5bf9\u80ba\u529f\u80fd\u3001\u54ee\u5598\u63a7\u5236\u6c34\u5e73\u53ca\u75f0\u55dc\u9178\u7c92\u7ec6\u80de\u708e\u75c7\u65e0\u660e\u663e\u5f71\u54cd\u3002<\/p>\n
\u6709\u75c5\u4f8b\u62a5\u9053\u663e\u793a\uff0c\u786b\u5511\u560c\u5464\u53ef\u4ee5\u51cf\u5c11\u91cd\u5ea6\u54ee\u5598\u60a3\u8005\u53e3\u670d\u6fc0\u7d20\u5242\u91cf\uff0c\u4ece 60 mg\/d \u5230 5 mg\/d\u3001\u51cf\u5c11\u54ee\u5598\u6025\u6027\u53d1\u4f5c\u9891\u7387\u548c\u6539\u5584\u80ba\u529f\u80fd\u3002<\/p>\n
\u8fd9\u4e9b\u836f\u7269\u5177\u6709\u4e00\u5b9a\u7684\u4e0d\u826f\u53cd\u5e94\uff0c\u53ea\u80fd\u5728\u4e13\u79d1\u533b\u5e08\u6307\u5bfc\u4e0b\u4f7f\u7528\u3002<\/p>\n
\u652f\u6c14\u7ba1\u70ed\u6210\u5f62\u672f\uff08BT\uff09<\/p>\n
BT \u662f\u4e00\u9879\u5728\u652f\u6c14\u7ba1\u955c\u4ecb\u5bfc\u4e0b\u8fdb\u884c\u7684\u975e\u836f\u7269\u6cbb\u7597\u6280\u672f\uff0c\u80fd\u591f\u51cf\u5c11\u6c14\u9053\u5e73\u6ed1\u808c\uff08ASM\uff09\u7684\u6570\u91cf\u3001\u964d\u4f4e ASM \u6536\u7f29\u529b\u3001\u6539\u5584\u54ee\u5598\u63a7\u5236\u6c34\u5e73\u3001\u63d0\u9ad8\u60a3\u8005\u751f\u6d3b\u8d28\u91cf\u5e76\u51cf\u5c11\u54ee\u5598\u836f\u7269\u7684\u4f7f\u7528\u3002<\/p>\n
1. \u9002\u5e94\u8bc1<\/p>\n
2010 \u5e74\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08FDA\uff09\u6279\u51c6\u5c06 BT \u7528\u4e8e 18 \u5c81\u53ca\u4ee5\u4e0a\u3001\u5e94\u7528 ICS \u548c LABA \u4ecd\u65e0\u6cd5\u6709\u6548\u63a7\u5236\u7684\u91cd\u75c7\u6301\u7eed\u6027\u54ee\u5598\u60a3\u8005\u3002\u6211\u56fd\u4e8e 2013 \u5e74\u5e95\u6b63\u5f0f\u6279\u51c6\u5c06\u8be5\u9879\u6280\u672f\u7528\u4e8e\u6cbb\u7597\u91cd\u5ea6\u54ee\u5598\u3002<\/p>\n
2. \u6709\u6548\u6027\u53ca\u5b89\u5168\u6027<\/p>\n
\u56fd\u5185\u5916\u5df2\u6709\u591a\u9879\u7814\u7a76\u8bc1\u5b9e BT \u6cbb\u7597\u7684\u6709\u6548\u6027\u53ca\u5b89\u5168\u6027\uff0c\u5305\u62ec\u672f\u540e 5 \u5e74\u7684\u968f\u8bbf\u663e\u793a BT \u6548\u679c\u6301\u7eed\u5b58\u5728\uff0c\u672a\u53d1\u73b0\u8fdc\u671f\u5e76\u53d1\u75c7\uff0cHRCT \u4ea6\u672a\u53d1\u73b0\u660e\u663e\u80ba\u90e8\u7ed3\u6784\u6539\u53d8\u3002<\/p>\n
\u6700\u65b0\u672f\u540e\u968f\u8bbf 10 \u5e74\u4ee5\u4e0a\u7684\u7814\u7a76\u663e\u793a\uff0cBT \u51cf\u5c11\u54ee\u5598\u4e25\u91cd\u53d1\u4f5c\u3001\u964d\u4f4e\u6025\u8bca\u5c31\u8bca\u7387\u548c\u4f4f\u9662\u7387\u3001\u6539\u5584\u54ee\u5598\u751f\u6d3b\u8d28\u91cf\u53ca\u54ee\u5598\u63a7\u5236\u7684\u7597\u6548\u53ef\u6301\u7eed 10 \u5e74\u53ca\u4ee5\u4e0a\uff0c\u5e76\u4e14\u5177\u6709\u826f\u597d\u5b89\u5168\u6027\uff0c\u4ec5\u6709\u6781\u5c11\u6570\u60a3\u8005\u65b0\u53d1\u652f\u6c14\u7ba1\u6269\u5f20\uff0c\u4f46\u7a0b\u5ea6\u8f83\u8f7b\uff0c\u4e14\u4e0e\u4e34\u5e8a\u52a0\u91cd\u65e0\u660e\u786e\u5173\u7cfb\u3002<\/p>\n
\u5bf9\u4e8e BT \u6cbb\u7597\u7684\u9002\u7528\u4eba\u7fa4\u53ca\u7597\u6548\u9884\u6d4b\u56e0\u7d20\u7684\u63a2\u7d22\u7814\u7a76\u663e\u793a\uff0c\u65e0\u8bba\u672f\u524d\u80ba\u529f\u80fd FEV1 \u2265 60% \u9884\u8ba1\u503c\u8fd8\u662f < 60% \u9884\u8ba1\u503c\uff0c\u65e0\u8bba\u652f\u6c14\u7ba1\u8212\u5f20\u8bd5\u9a8c\u7ed3\u679c\u5982\u4f55\uff0c\u60a3\u8005\u5747\u53ef\u4ece BT \u6cbb\u7597\u4e2d\u83b7\u76ca\u3002<\/p>\n
3. \u56f4\u624b\u672f\u671f\u7ba1\u7406<\/p>\n
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#artContent h1#artContent p img#artContent table<\/p>\n","protected":false},"excerpt":{"rendered":"
\u91cd\u5ea6\u54ee\u5598\u662f\u54ee\u5598\u60a3\u8005\u81f4\u6b8b\u3001\u81f4\u6b7b\u7684\u4e3b\u8981\u539f\u56e0\uff0c\u5177\u6709\u9ad8\u5ea6\u7684\u75be\u75c5\u672a\u6765\u98ce\u9669\uff0c\u4e5f\u9020\u6210\u4e86\u4e25\u91cd\u7684\u793e … \u7ee7\u7eed\u9605\u8bfb