{"id":39355,"date":"2024-08-07T05:10:18","date_gmt":"2024-08-07T05:10:18","guid":{"rendered":"https:\/\/zydq.1006ss.com\/?p=39355"},"modified":"2024-08-07T05:10:18","modified_gmt":"2024-08-07T05:10:18","slug":"%e7%94%9f%e5%8c%96%e7%af%87-%e7%b3%96%e4%bb%a3%e8%b0%a21","status":"publish","type":"post","link":"http:\/\/zydq.1006ss.com\/?p=39355","title":{"rendered":"\u751f\u5316\u7bc7\u2014\u2014\u7cd6\u4ee3\u8c221"},"content":{"rendered":"

\u751f\u5316\u00b7\u7cd6\u4ee3\u8c22<\/p>\n

-DECEMBER-<\/p>\n

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01<\/p>\n

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\u53d1\u751f\u90e8\u4f4d\u5728\u80de\u6db2\u53ca\u7ebf\u7c92\u4f53<\/p>\n

\u540c\u6837\u7684\uff0c\u6709\u6c27\u6c27\u5316\u7684\u7b2c\u4e00\u9636\u6bb5\u4e5f\u662f\u7cd6\u9175\u89e3\uff0c\u524d\u6587\u5df2\u7ecf\u8be6\u7ec6\u8bb2\u8fc7\u4e86\uff0c\u8fd9\u91cc\u5c31\u4e0d\u518d\u8d58\u8ff0\u3002<\/p>\n<\/p>\n

\u6709\u6c27\u6c27\u5316\u7684\u7b2c\u4e8c\u9636\u6bb5\u662f\u4e19\u916e\u9178\u8fdb\u5165\u7ebf\u7c92\u4f53\u6c27\u5316\u8131\u7fa7\u751f\u6210\u4e59\u9170\u8f85\u9176A\uff0c\u6b64\u53cd\u5e94\u7531\u4e19\u916e\u9178\u8131\u6c22\u9176\u590d\u5408\u4f53\u50ac\u5316\uff0c\u6b64\u53cd\u5e94\u4e0d\u53ef\u9006\uff0c\u56e0\u6b64\u8be5\u9176\u4e5f\u662f\u5173\u952e\u9176\u3002\u4e19\u916e\u9178\u8131\u6c22\u9176\u662f\u4e09\u4e2a\u9176\u7ec4\u5408\u800c\u6210\u7684\u590d\u5408\u4f53\uff0c\u9700\u8981\u8bb0\u4f4f\u7684\u662f\u5176\u53c2\u4e0e\u53cd\u5e94\u7684\u8f85\u52a9\u56e0\u5b50\u6709\uff1a\u7126\u78f7\u9178\u786b\u6c28\u9178\uff08TPP\uff09\u786b\u8f9b\u9178 FAD NAD+<\/sup> CoA<\/p>\n

\u4e19\u916e\u9178\u8131\u6c22\u9176\u590d\u5408\u4f53\u7684\u8c03\u8282\u6709\u522b\u6784\u6291\u5236\u5242\u2014\u2014\u4e59\u9170\u8f85\u9176A\uff08\u4ea7\u7269\u6291\u5236\uff09\u3001NADH\uff08\u4ea7\u7269\u6291\u5236\uff09\u548cATP\uff1b\u522b\u6784\u6fc0\u6d3b\u2014\u2014AMP ADP NAD+<\/sup>\uff08\u5e95\u7269\uff09<\/p>\n

\u6709\u6c27\u6c27\u5316\u6700\u91cd\u8981\u7684\u662f\u7b2c\u4e09\u9636\u6bb5\u7684\u4e09\u7fa7\u9178\u5faa\u73af\uff08\u53c8\u79f0\u67e0\u6aac\u9178\u5faa\u73af\u6216Krebs\u5faa\u73af\uff09\uff0c\u7b80\u8a00\u4e4b\u5c31\u662f\u4e59\u9170\u8f85\u9176A\u4e0e\u8349\u9170\u4e59\u9178\u7f29\u5408\u751f\u6210\u67e0\u6aac\u9178\uff0c\u7ecf\u8fc7\u4e00\u7cfb\u5217\u53cd\u5e94\u91cd\u65b0\u53d8\u6210\u8349\u9170\u4e59\u9178\u5b8c\u6210\u4e00\u8f6e\u5faa\u73af\uff0c\u5176\u4e2d\u8131\u4e0b\u7684\u6c22\u7ecf\u547c\u5438\u94fe\u751f\u6210\u6c34\u5e76\u4ea7\u751fATP\uff0c\u800cCO2\u7ecf\u547c\u5438\u7cfb\u7edf\u88ab\u6392\u51fa\u3002\u8fd9\u91cc\u6709\u53e3\u8bc0\u53ef\u4ee5\u4f9b\u5927\u5bb6\u53c2\u8003\u4e00\u4e0b\uff1a\u5b81\u5f02\u52ff\u540c\uff0c\u864e\u864e\u5ef6\u5e73\u3002<\/p>\n

\u4e09\u7fa7\u9178\u5faa\u73af\u4e2d\u6709\u4e09\u4e2a\u5173\u952e\u9176\uff0c\u5206\u522b\u662f\u67e0\u6aac\u9178\u5408\u9176\u3001\u5f02\u67e0\u6aac\u9178\u8131\u6c22\u9176\u548c\u03b1-\u916e\u620a\u4e8c\u9178\u8131\u6c22\u9176\u590d\u5408\u4f53\u3002<\/p>\n

\u67e0\u6aac\u9178\u5408\u9176\uff1a\u50ac\u5316\u4e0d\u53ef\u9006\u53cd\u5e94<\/p>\n

\u5f02\u67e0\u6aac\u9178\u8131\u6c22\u9176\uff1a\u7b2c\u4e00\u6b21\u6c27\u5316\u8131\u7fa7\uff08\u03b2-\u6c27\u5316\u8131\u7fa7\uff09\uff0c\u6b64\u53cd\u5e94\u4e0d\u53ef\u9006\uff0c\u4ea7\u751f1\u5206\u5b50\u4e8c\u6c27\u5316\u78b3\u548c1\u5bf9NADH+H+<\/sup><\/p>\n

\u03b1-\u916e\u620a\u4e8c\u9178\u8131\u6c22\u9176\u590d\u5408\u4f53\uff08\u4e0e\u4e19\u916e\u9178\u8131\u6c22\u9176\u7c7b\u4f3c\uff0c\u4e8c\u8005\u53ef\u4ee5\u7c7b\u6bd4\u8bb0\u5fc6\uff09\uff1a\u7b2c\u4e8c\u6b21\u6c27\u5316\u8131\u7fa7\uff08\u03b1-\u6c27\u5316\u8131\u7fa7\uff09\uff0c\u6b64\u53cd\u5e94\u4e0d\u53ef\u9006\uff0c\u4ea7\u751f1\u5206\u5b50\u4e8c\u6c27\u5316\u78b3\u548c1\u5bf9NADH+H+<\/sup><\/p>\n

\u5173\u952e\u9176\u7684\u8c03\u8282\u4e5f\u975e\u5e38\u91cd\u8981\uff0c\u8fd9\u91cc\u653e\u4e00\u5f20\u56fe\uff0c\u56fe\u89e3\u975e\u5e38\u6e05\u695a\u5566~<\/p>\n<\/p>\n

\u4e00\u6b21\u5e95\u7269\u6c34\u5e73\u78f7\u9178\u5316\uff1a\u7425\u73c0\u9170\u8f85\u9176A\u8f6c\u53d8\u4e3a\u7425\u73c0\u9178\uff0c\u6b64\u53cd\u5e94\u7684\u9176\u662f\u7425\u73c0\u9178\u786b\u6fc0\u9176\uff08\u53c8\u79f0\u7425\u73c0\u9178\u5408\u9176\uff09\uff0c\u6b64\u53cd\u5e94\u53ef\u9006\uff0c\u8be5\u9176\u4e0d\u662f\u5173\u952e\u9176\uff0c\u662fTCA\u4e2d\u552f\u4e00\u4e00\u6b21\u5e95\u7269\u6c34\u5e73\u78f7\u9178\u5316\u53cd\u5e94\uff0c\u751f\u62101\u5206\u5b50GTP\u3002<\/p>\n

\u4e24\u6b21\u8131\u7fa7\u53cd\u5e94\uff1a\u5206\u522b\u662f\u524d\u6587\u6240\u8bf4\u7684\u5f02\u67e0\u6aac\u9178\u8131\u6c22\u9176\u548c\u03b1-\u916e\u620a\u4e8c\u9178\u8131\u6c22\u9176\u590d\u5408\u4f53\u50ac\u5316\u7684\u53cd\u5e94\uff0c\u5404\u751f\u62101\u5206\u5b50CO2<\/sub><\/p>\n

\u56db\u6b21\u8131\u6c22\u53cd\u5e94\uff1a\u5206\u522b\u662f\u5f02\u67e0\u6aac\u9178\u751f\u6210\u03b1-\u916e\u620a\u4e8c\u9178\u3001\u03b1-\u916e\u620a\u4e8c\u9178\u751f\u6210\u7425\u73c0\u9170\u8f85\u9176A\u3001\u82f9\u679c\u9178\u751f\u6210\u8349\u9170\u4e59\u9178\u548c\u7425\u73c0\u9178\u751f\u6210\u5ef6\u80e1\u7d22\u9178\u3002\u5176\u4e2d\u524d\u4e09\u4e2a\u8f85\u56e0\u5b50\u90fd\u662fNAD+<\/sup>\uff0c\u751f\u6210NADH+H+<\/sup>\u53ea\u6709\u6700\u540e\u4e00\u4e2a\u8f85\u56e0\u5b50\u662fFAD\uff0c\u751f\u6210FADH2<\/sub><\/p>\n

\u603b\u7ed3\u4e00\u4e0b\uff0cTCA\u8fd0\u8f6c\u4e00\u5468\u7684\u51c0\u7ed3\u679c\u662f\u6c27\u53161\u5206\u5b50\u4e59\u9170CoA\uff0c\u8349\u9170\u4e59\u9178\u4ec5\u8d77\u8f7d\u4f53\u4f5c\u7528\uff0c\u53cd\u5e94\u524d\u540e\u65e0\u6539\u53d8\uff0c\u800cC\u6765\u6e90\u4e8e\u8349\u9170\u4e59\u9178\uff0c\u800c\u4e0d\u662f\u6765\u81ea\u4e59\u9170\u8f85\u9176A\u3002\u4e14\u6574\u4e2a\u5faa\u73af\u662f\u4e0d\u53ef\u9006\u53cd\u5e94<\/p>\n

\u7cd6\u6709\u6c27\u6c27\u5316\u548c\u65e0\u6c27\u6c27\u5316\u4e4b\u95f4\u4e5f\u5b58\u5728\u4e00\u5b9a\u7684\u8054\u7cfb\uff0c\u7cd6\u6709\u6c27\u6c27\u5316\u53ef\u4ee5\u6291\u5236\u65e0\u6c27\u6c27\u5316\uff0c\u8fd9\u662f\u5df4\u65af\u5fb7\u6548\u5e94<\/p>\n

03<\/p>\n

\u78f7\u9178\u620a\u7cd6\u9014\u5f84<\/p>\n

\u78f7\u9178\u620a\u7cd6\u9014\u5f84\u662f\u6307\u4ece\u7cd6\u9175\u89e3\u7684\u4e2d\u95f4\u4ea7\u7269G-6-P\u5f00\u59cb\u5f62\u6210\u65c1\u8def\uff0c\u901a\u8fc7\u6c27\u5316\u3001\u57fa\u56e2\u8f6c\u79fb\u4e24\u4e2a\u9636\u6bb5\u751f\u6210F-6-P\u548c3-\u78f7\u9178\u7518\u6cb9\u919b\uff0c\u4ece\u800c\u8fd4\u56de\u7cd6\u9175\u89e3\u7684\u4ee3\u8c22\u9014\u5f84\u3002<\/p>\n

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\u7b2c\u4e8c\u9636\u6bb5\u4e2d\uff0c5-\u78f7\u9178\u6838\u7cd6\u6700\u7ec8\u8f6c\u53d8\u4e3aF-6-P\u548c3-\u78f7\u9178\u7518\u6cb9\u919b\uff1b\u8fd9\u4e00\u9636\u6bb5\u975e\u5e38\u91cd\u8981\uff0c\u56e0\u4e3a\u7ec6\u80de\u5bf9NADPH\u7684\u6d88\u8017\u91cf\u8fdc\u5927\u4e8e\u78f7\u9178\u620a\u7cd6\uff0c\u591a\u4f59\u7684\u620a\u7cd6\u9700\u8981\u901a\u8fc7\u6b64\u53cd\u5e94\u8fd4\u56de\u7cd6\u9175\u89e3\u7684\u4ee3\u8c22\u9014\u5f84\u518d\u6b21\u5229\u7528<\/p>\n

\u603b\u7ed3\u6765\u8bf4\uff0c1\u5206\u5b50G-6-P\u7ecf\u8fc7\u53cd\u5e94\uff0c\u53ea\u80fd\u53d1\u751f\u4e00\u6b21\u8131\u7fa7\u548c\u4e24\u6b21\u8131\u6c22\u53cd\u5e94\uff0c\u751f\u62101\u5206\u5b50CO2<\/sub>\u548c2\u5206\u5b50NADPH+H+<\/sup>\u3002<\/p>\n

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\u4ee5\u4e0a\u5c31\u662f\u7cd6\u5206\u89e3\u7684\u6240\u6709\u5185\u5bb9\u5566~<\/p>\n

\u795d\u540c\u5b66\u4eec\u5b66\u4e60\u5feb\u4e50~~<\/p>\n","protected":false},"excerpt":{"rendered":"

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