\u3010\u62fc\u97f3\u540d\u3011Hu\u00e1n\u0261 C\u01ceo W\u016b<\/p>\n
\u3010\u6765\u6e90\u3011
\u836f\u6750\u57fa\u6e90\uff1a\u4e3a\u6bdb\u831b\u79d1\u690d\u7269\u4e3d\u6c5f\u4e4c\u5934\u7684\u5757\u6839\u3002
\u62c9\u4e01\u690d\u7269\u52a8\u7269\u77ff\u7269\u540d\uff1aAconitum forrestii Stapf[A.lidiangense Chen et Liu]
\u91c7\u6536\u548c\u50a8\u85cf\uff1a\u79cb\u5b63\u91c7\u6316\uff0c\u9664\u53bb\u987b\u6839\u3001\u6b8b\u830e\uff0c\u591a\u9c9c\u7528\u6216\u6652\u5e72\u3002<\/p>\n
\u3010\u539f\u5f62\u6001\u3011\u4e3d\u6c5f\u4e4c\u5934\uff0c\u591a\u5e74\u751f\u8349\u672c\uff0c\u9ad870-100cm\u3002\u5757\u6839\u80e1\u841d\u535c\u72b6\uff0c\u957f\u7ea65.5cm\uff0c\u76f4\u5f841.6cm\u3002\u830e\u76f4\u7acb\uff0c\u88ab\u53cd\u66f2\u7684\u77ed\u67d4\u6bdb\u3002\u53f6\u4e92\u751f\uff1b\u830e\u4e0b\u90e8\u53f6\u5728\u5f00\u82b1\u65f6\u67af\u840e\uff0c\u5177\u7a0d\u957f\u67c4\uff1b\u830e\u4e2d\u90e8\u4ee5\u4e0a\u53f6\u5177\u77ed\u67c4\uff0c\u53f6\u67c4\u957f2-10mm\uff1b\u53f6\u7247\u5bbd\u5375\u5f62\u6216\u4e94\u89d2\u72b6\u5375\u5f62\uff0c\u957f7-12cm\uff0c\u5bbd7-10cm\uff0c\u57fa\u90e8\u5fc3\u5f62\uff0c3\u6df1\u88c2\u7a0d\u8d85\u8fc7\u4e2d\u90e8\u6216\u81f3\u672c\u8eab\u957f\u5ea64\/5\u5904\uff0c\u6df1\u88c2\u7247\u8fd1\u4eca\u63a5\uff0c\u4e24\u9762\u88ab\u77ed\u67d4\u6bdb\u3002\u603b\u72b6\u82b1\u5e8f\u9876\u751f\uff0c\u5177\u591a\u6570\u5bc6\u96c6\u7684\u82b1\uff1b\u82b1\u5e8f\u8f74\u548c\u82b1\u6897 \u5bc6\u88ab\u4f38\u5c55\u7684\u6de1\u9ec4\u8272\u77ed\u67d4\u6bdb\uff0c\u5e76\u6df7\u751f\u53cd\u66f2\u77ed\u67d4\u6bdb\uff1b\u4e0b\u90e8\u82de\u7247\u53f6\u72b6\uff0c\u4e2d\u90e8\u4ee5\u4e0a\u82de\u7247\u957f\u5706\u72b6\u7ebf\u5f62\uff1b\u82b1\u6897\u957f1-2.5cm\uff1b\u5c0f\u82de\u7247\u72ed\u957f\u5706\u5f62\u6216\u7ebf\u5f62\uff0c\u82b1\u4e24\u6027\uff0c\u4e24\u4fa7\u5bf9\u79f0\uff1b\u843c\u72475\uff0c\u82b1\u74e3\u72b6\uff0c\u7d2b\u84dd\u8272\uff0c\u5916\u9762\u88ab\u77ed\u67d4\u6bdb\uff0c\u4e0a\u843c\u7247\u76d4\u5f62\uff0c\u5bbd0.9-1.1cm\uff0c\u57fa\u90e8\u81f3\u5599\u957f1.7-2cm\uff0c\u5599\u77ed\uff1b\u82b1\u74e32\uff0c\u65e0\u6bdb\uff0c\u5148\u7aef\u5411\u5916\u5f2f\uff0c\u5507\u957f\u7ea65mm\uff0c2\u6d45\u88c2\uff0c\u8ddd\u957f\u7ea61mm\uff0c\u534a\u5706\u5f62\uff0c\u7a0d\u5411\u540e\u5f2f\uff1b\u96c4\u854a\u591a\u6570\uff0c\u65e0\u6bdb\uff0c\u82b1\u4e1d\u5168\u7f18\uff1b\u5fc3\u76ae5\uff0c\u65e0\u6bdb\u3002\u84c7\u8456\u679c\u3002\u79cd\u5b50\u591a\u6570\u3002\u82b1\u671f9\u6708\uff0c\u679c\u671f10\u6708\u3002<\/p>\n
\u3010\u751f\u5883\u5206\u5e03\u3011
\u751f\u6001\u73af\u5883\uff1a\u751f\u4e8e\u6d77\u62d43100m\u4e00\u5e26\u7684\u5c71\u5730\u8349\u5761\u6216\u6797\u8fb9\u3002
\u8d44\u6e90\u5206\u5e03\uff1a\u5206\u5e03\u4e8e\u56db\u5ddd\u897f\u5357\u90e8\u6728\u91cc\u3001\u4e91\u5357\u897f\u5317\u90e8\u4e3d\u6c5f\u3002<\/p>\n
\u3010\u6027\u72b6\u3011
\u6027\u5934\u8111 \u9274\u522b\uff0c\u6839\u5706\u9525\u5f62\uff0c\u957f4-5cm\uff0c\u76f4\u5f841-1.5cm\u3002\u8868\u9762\u68d5\u8272\u81f3\u6df1\u68d5\u8272\uff0c\u6bcd\u6839\u5177\u4e0d\u89c4\u5219\u7eb5\u76b1\u7f29\u7eb9\u53ca\u987b\u6839\u75d5\uff1b\u5b50\u6839\u7a0d\u5149\u6ed1\uff0c\u5177\u5c11\u6570\u70b9\u72b6\u987b\u6839\u75d5\u3002\u8d28\u575a\u786c\uff0c\u4e0d\u6613\u6298\u65ad\uff0c\u65ad\u9762\u767d\u8272\uff0c\u53ef\u89c1\u5c11\u6570\u6df1\u68d5\u8272\u6563\u5217\u7684\u5c0f\u70b9\u3002
\u663e\u5fae\u9274\u522b\uff0c\u6839\u6a2a\u5207\u9762\uff1a\u540e\u751f\u7834\u5c42\u4e3a3-4\u5217\u68d5\u8272\u7ec6\u80de\uff1b\u76ae\u5c42\u7ec6\u80de5-6\u5217\uff0c\u7c7b\u957f\u65b9\u5f62\uff0c\u5207\u5411\u6392\u5217\uff0c\u77f3\u7ec6\u80de\u5bc6\u96c6\u3002\u5185\u76ae\u5c42\u663e\u7740\uff0c\u590d\u5408\u7684\u5916\u97e7\u578b\u7ef4\u7ba1\u6570\u4e2a\u73af\u5217\uff0c\u6bcd\u6839\u7684\u6bcf\u4e2a\u7ef4\u7ba1\u675f\u7684\u5916\u4fa7\u6709\u76b1\u7f29\u7684\u8584\u58c1\u7ec6\u80f8\u6000\u4e0d\uff0c\u5b50\u6839\u7684\u590d\u5408\u7ef4\u7ba1\u675f5-6\u4e2a\u3002\u5f62\u6210\u5c42\u73af\u7c7b\u957f\u5706\u5f62\uff0c\u6728\u8d28\u90e8\u675f\u5bfc\u7ba1\u5448\u5f84\u5411\u6216V\u5b57\u5f62\u63d0\u5217\u3002
\u7c89\u672b\u7279\u5f81\uff1a1.\u77f3\u7ec6\u80de\u591a\uff0c\u957f\u6761\u5f62\u3001\u7c7b\u65b9\u5f62\u3001\u957f\u65b9\u5f62\u6216\u9525\u5f62\uff0c\u957f50-256\u03bcm\uff0c\u76f4\u5f8420-50\u03bcm\uff0c\u7eb9\u5b54\u53ca\u5b54\u6c9f\u660e\u663e\uff0c\u58c1\u539a\u6216\u7a0d\u539a\u30022.\u6dc0\u7c89\u7c92\u5355\u7c92\u5448\u957f\u5706\u5f62\u3001\u76d4\u5e3d\u5f62\u6216\u5916\u5411\u9524\u5f62\uff0c\u76f4\u5f846-24\u03bcm\uff0c\u8110\u70b9\u5448\u70b9\u72b6\u3001\u4e00\u5b57\u5f62\u3001\u516b\u5b57\u5f62\uff1b\u590d\u7c92\u75312\u5206\u7c92\u7ec4\u6210\u3002<\/p>\n
\u3010\u5316\u5b66\u6210\u4efd\u3011\u4e3d\u6c5f\u4e4c\u5934\u5757\u6839\u542b\u7c97\u830e\u4e4c\u5934\u78b1\u7532(crassicaulineA)\uff0c\u4e3d\u4e4c\u78b1(liwaconitine)\uff0c\u5c55\u82b1\u4e4c\u5934\u78b1(chasmaconitine)\uff0c\u4e4c\u5934\u8bfa\u8f9b(aconosine)\uff0c\u5361\u9a6c\u4e4c\u5934\u539f\u78b1(cammaconine)\uff0c8-\u53bb\u4e59\u9170\u6ec7\u4e4c\u78b1(8-deacetylyunaconitine)\uff0c\u5854\u62c9\u80fa(talatisamine)\uff0c\u5c55\u82b1\u4e4c\u5934\u5b81(chasmanine)\uff0c\u4f5b\u6c0f\u4e4c\u5934\u4ead(forestine)\uff0c\u4f5b\u6c0f\u4e4c\u5934\u8f9b(foresticine)\uff0c\u6ec7\u4e4c\u78b1(yunaconitine)\uff0c\u4e3d\u6c5f\u4e4c\u5934\u78b1(foresaconitine)\uff0c\u5373\u662f\u9ec4\u8349\u4e4c\u78b1\u4e19(vilmorrizaninec)\uff0c\u4e3d\u6c5f\u4e4c\u4efb\u78b1(acoforine)\uff0c\u4e3d\u6c5f\u4e4c\u5934\u8f9b\u78b1(acoforesticine)\u4e3d\u6c5f\u4e4c\u5934\u4ead\u78b1(acpfprestinine)\uff0c\u55dc\u5566\u4e4c\u5934\u539f\u78b1(dolaconine)\uff0c\u4e3d\u65e5\u78b1\u7532(liconosine A)\uff0c3-\u53bb\u7f9f-8-\u53bb\u4e59\u9170\u6ec7\u4e4c\u78b1(3-deoxy-8-deacetyl yunaconitine)\uff0c3\u03b1\uff0c13-\u4e8c\u7f9f\u57fa\u4e3d\u6c5f\u4e4c\u5934\u78b1(3\u03b1,13-dihydroxyforesaconitine)\u7b49\u751f\u7269\u78b1\u3002\u8fd8\u542b\u8334\u9999\u9178(anisic acid)\u3002<\/p>\n
\u3010\u836f\u7406\u4f5c\u7528\u3011
1.\u6297\u708e\u4f5c\u7528\uff0c\u6ec7\u4e4c\u78b1\u76ae\u4e0b\u6ce8\u5c0410-80\u03bcg\/kg\u6216\u704c\u670d50-100\u03bcg\/kg\u4e8e\u5927\u9f20\u6216\u5c0f\u9f20\uff0c\u5bf9\u918b\u9178\u3001\u7ec4\u80fa\u7b49\u6240\u81f4\u8179\u8154\u6216\u76ae\u80a4\u6bdb\u7ec6\u8840\u7ba1\u901a\u900f\u6027\u589e\u9ad8\u6709\u663e\u7740\u7684\u6291\u5236\u4f5c\u7528\uff0c\u5e76\u80fd\u660e\u663e\u6291\u5236\u4e8c\u7532\u82ef\u6240\u81f4\u5c0f\u9f20\u8033\u80bf\uff0c\u6291\u5236\u89d2\u53c9\u83dc\u80f6\u3001\u86cb\u6e05\u53ca\u7532\u919b\u6240\u81f4\u5927\u9f20\u8db3\u8dd6\u6c34\u80bf\uff0c\u5bf9\u89d2\u53c9\u83dc\u80f6\u6240\u81f4\u5927\u9f20\u80f8\u8154\u767d\u7ec6\u80de\u6e38\u8d70\u4ee5\u53ca\u68c9\u7403\u6240\u81f4\u7ec4\u7ec7\u589e\u751f\u4e5f\u5747\u6709\u663e\u7740\u6291\u5236\u4f5c\u7528\u3002\u6458\u9664\u53cc\u4fa7\u80be\u4e0a\u817a\u540e\u4ecd\u5177\u6709\u6297\u708e\u4f5c\u7528\uff0c\u4f46\u6ec7\u4e4c\u78b1\u4e0d\u80fd\u5904\u957f\u53bb\u80be\u4e0a\u817a\u5927\u9f20\u7684\u751f\u5b58\u65f6\u95f4\uff0c\u4e5f\u4e0d\u5f71\u54cd\u817a\u548c\u575a\u4e0a\u817a\u91cd\u91cf\uff0c\u8868\u660e\u6ec7\u4e4c\u78b1\u6297\u708e\u4f5c\u7528\u4e0e\u5782\u4f53-\u80be\u4e0a\u817a\u76ae\u8d28\u7cfb\u7edf\u65e0\u5173\u3002
2.\u9547\u75db\u4f5c\u7528\uff0c\u5c0f\u9f20\u76ae\u4e0b\u6ce8\u5c04\u6ec7 \u4e4c\u78b110\u03bcg\/kg\uff0c20\u03bcg\/kg\uff0c40\u03bcg\/kg\uff0c80\u03bcg\/kg\uff0c100\u03bcg\/kg\u7684\u626d\u4f53\u53cd\u5e94\u6291\u5236\u7387\u5206\u522b\u4e3a15%\uff0c25%\uff0c45%\uff0c71%\u548c87%\uff0cED50\u4e3a39(34-44)\u03bcg\/kg\u3002\u70ed\u677f\u6cd5\u8bd5\u9a8c20\u03bcg\/kg\uff0c50\u03bcg\/kg\u548c100\u03bcg\/kg\u7684\u51f6\u5236\u7387\u5206\u522b\u4e3a20%\uff0c60%\u53ca80%\uff0cED50\u4e3a42(37-49)\u03bcg\/kg\u3002\u5bf9\u4e00\u7532\u919b\u6240\u81f4\u5927\u9f20\u811a\u722a\u75bc\u75db\uff0c\u76ae\u4e0b\u6ce8\u5c0410\u03bcg\/kg\uff0c30\u03bcg\/kg\u7684\u9547\u75db\u7387\u4e3a16%\u548c50%\u3002
3.\u89e3\u70ed\u4f5c\u7528\uff0c\u5bf9\u9175\u6bcd\u6240\u81f4\u5927\u9f20\u53d1\u70ed\uff0c\u704c\u670d\u6ec7\u4e4c\u592750\u03bcg\/kg\uff0c100\u03bcg\/kg\u6709\u663e\u7740\u624d\u7684\u89e3\u70ed\u4f5c\u7528\u3002
4.\u5bf9\u514d\u75ab\u529f\u80fd \u7684\u5f71\u54cd\uff0c\u5c0f\u9f20\u5bf9\u8840\u4e2d\u78b3\u7c92\u7684\u719f\u6e05\u8bd5\u9a8c\uff0c\u8179\u8154\u6ce8\u5c04\u6ec7\u4e4c\u78b150\u03bcg\/kg\u8fde\u7eed4\u5929\uff0c\u53ef\u660e\u663e\u63d0\u9ad8\u541e\u566c\u6307\u6570\u548c\u541e\u566c\u7cfb\u6570\uff0c\u4f46\u53bb\u4f7f\u5c0f\u9f20\u809d\u3001\u813e\u91cd\u91cf\u660e\u663e\u51cf\u8f7b\uff0c20\u03bcg\/kg\u65e0\u660e\u663e\u5f71\u54cd\u300220\u03bcg\/kg\uff0c50\u03bcg\/kg\u8fd8\u80fd\u4f7f\u5c0f\u9f20\u8840\u6e05\u603b\u8865\u4f53\u6d3b\u6027\u660e\u663e\u5347\u9ad8\uff0c\u4f46\u5bf9C3\u542b\u91cf\u7684\u5f71\u54cd\u4e0d\u660e\u663e\u3002\u5bf9\u4e8e\u7ef5\u7f8a\u7ea2\u7ec6\u80de(SRBC)\u514d\u75ab\u6240\u81f4\u5c0f\u9f20\u6eb6\u8840\u7d20\u6297\u4f53\u7684\u751f\u6210\u53ca\u6eb6\u8840\u7a7a\u6591\u5f62\u6210\u7ec6\u80de\u6570\u6ec7 \u4e4c\u78b1\u65e0\u660e\u663e\u5f71\u54cd\uff0c\u6216\u6709\u6240\u6291\u5236\uff0c\u4f46\u5bf9IgG\u65e0\u660e\u663e\u5f71\u54cd\u300250\u03bcg\/kg\u8179\u8154\u6ce8\u5c04\u80fd\u663e\u7740\u5ef6\u957f\u5c0f\u9f20\u8033\u540e\u79fb\u690d\u5fc3\u808c\u7684\u5b58\u6d3b\u65f6\u95f4\uff0c\u5bf9\u5927\u9f20\u5b9e\u9a8c\u6027\u53d8\u6001\u53cd\u5e94\u6027\u8111\u810a\u9ad3\u708e\u6709\u6291\u5236\u503e\u5411\u3002
5.\u6bd2\u6027\uff0c\u6ec7\u4e4c\u78b1\u7684LD50\u5c0f\u9f20\u704c\u670d\u3001\u76ae\u4e0b\u6ce8\u5c04\u548c\u8179\u8154\u6ce8\u5c04\u5206\u522b\u4e3a12.97(2.95-2.99)mg\/kg,0.37(0.35-0.39)mg\/kg,0.34(0.32-0.36)mg\/kg\uff1b\u5927\u9f20\u5219\u5206\u522b\u4e3a540(490-590)\u03bcg\/kg\uff0c67(64-70)\u03bcg\/kg\u53ca60(57-63)\u03bcg\/kg\u3002\u4e2d\u6bd2\u75c7\u72b6\u4e3a\u6d3b\u52a8\u51cf\u5c11\uff0c\u95ed\u76ee\u5310\u4f0f\uff0c\u6d41\u6d8e\uff0c\u5455\u5410\u6837\u53cd\u5e94\uff0c\u540e\u80a2\u8f6f\u762b\uff0c\u547c\u5438\u6291\u5236\u4e00\u822c\u5728\u836f\u540e1h\u5de6\u53f3\u6b7b\u4ea1\uff0c\u6b7b\u524d\u6709\u62bd\u6410\u3002<\/p>\n
\u3010\u6027\u5473\u3011\u5473\u8f9b\uff1b\u6027\u6e29\uff1b\u5927\u6bd2<\/p>\n
\u3010\u529f\u80fd\u4e3b\u6cbb\u3011\u795b\u98ce\u6e7f\uff1b\u9547\u75db\u3002\u4e3b\u98ce\u6e7f\u5173\u8282\u75bc\u75db\uff1b\u8dcc\u6253\u635f\u4f24<\/p>\n
\u3010\u6458\u5f55\u3011\u300a\u4e2d\u534e\u672c\u8349\u300b<\/p>\n","protected":false},"excerpt":{"rendered":"
\u3010\u62fc\u97f3\u540d\u3011Hu\u00e1n\u0261 C\u01ceo W\u016b \u3010\u6765\u6e90\u3011\u836f\u6750\u57fa\u6e90\uff1a\u4e3a\u6bdb\u831b\u79d1\u690d\u7269\u4e3d\u6c5f\u4e4c\u5934\u7684\u5757\u6839 … \u7ee7\u7eed\u9605\u8bfb