{"id":38130,"date":"2024-07-09T05:10:18","date_gmt":"2024-07-09T05:10:18","guid":{"rendered":"https:\/\/zydq.1006ss.com\/?p=38130"},"modified":"2024-07-09T05:10:18","modified_gmt":"2024-07-09T05:10:18","slug":"%e3%80%90%e7%bb%bc%e8%bf%b0%e3%80%91%e8%a1%80%e6%b6%b2%e9%80%8f%e6%9e%90%e6%82%a3%e8%80%85%e7%98%99%e7%97%92%e7%97%87%e7%9a%84%e5%8f%91%e7%97%85%e6%9c%ba%e5%88%b6%e5%8f%8a%e8%8d%af%e7%89%a9%e6%b2%bb","status":"publish","type":"post","link":"http:\/\/zydq.1006ss.com\/?p=38130","title":{"rendered":"\u3010\u7efc\u8ff0\u3011\u8840\u6db2\u900f\u6790\u60a3\u8005\u7619\u75d2\u75c7\u7684\u53d1\u75c5\u673a\u5236\u53ca\u836f\u7269\u6cbb\u7597\u8fdb\u5c55"},"content":{"rendered":"

\u6c64\u6653\u9759  \u6885\u957f\u6797<\/p>\n

\uff08\u6d77\u519b\u519b\u533b\u5927\u5b66\u7b2c\u4e8c\u9644\u5c5e\u533b\u9662\u80be\u810f\u75c5\u79d1\uff0c\u4e0a\u6d77 200003\uff09<\/p>\n

\u901a\u4fe1\u4f5c\u8005\uff1a\u6885\u957f\u6797\uff0cEmail\uff1achlmei1954@126.com<\/p>\n

DOI\uff1a10.3760\/cma.j.cn441217-20230413-00420<\/p>\n

\u6458 \u8981 \u6162\u6027\u80be\u810f\u75c5\u76f8\u5173\u6027\u7619\u75d2\u75c7\uff08chronic kidney disease-associated pruritus\uff0cCKD-aP\uff09\u662f\u8840\u6db2\u900f\u6790\u60a3\u8005\u5e38\u89c1\u4e14\u96be\u4ee5\u5fcd\u53d7\u7684\u5e76\u53d1\u75c7\uff0c\u4e0d\u4ec5\u4e25\u91cd\u5f71\u54cd\u5176\u751f\u6d3b\u8d28\u91cf\u548c\u8eab\u5fc3\u5065\u5eb7\uff0c\u800c\u4e14\u589e\u52a0\u5176\u8fdc\u671f\u6b7b\u4ea1\u98ce\u9669\u3002CKD-aP\u7684\u53d1\u75c5\u673a\u5236\u4ecd\u4e0d\u660e\u786e\uff0c\u514d\u75ab\u708e\u75c7\u5931\u8c03\u3001\u5185\u6e90\u6027\u963f\u7247\u7c7b\u7cfb\u7edf\u5931\u8861\u3001\u4ee3\u8c22\u4ea7\u7269\u5f02\u5e38\u84c4\u79ef\u3001\u76ae\u80a4\u5e72\u71e5\u75c7\u3001\u7ec4\u80fa\u6c34\u5e73\u5f02\u5e38\u3001\u7532\u72b6\u65c1\u817a\u529f\u80fd\u4ea2\u8fdb\u7b49\u56e0\u7d20\u90fd\u88ab\u8bc1\u5b9e\u4e0e\u5176\u76f8\u5173\u3002CKD-aP\u76ee\u524d\u7f3a\u4e4f\u6ee1\u610f\u3001\u7279\u6548\u7684\u6cbb\u7597\u7b56\u7565\uff0c\u4e3b\u8981\u5305\u62ec\u836f\u7269\u6cbb\u7597\u3001\u975e\u836f\u7269\u6cbb\u7597\u548c\u900f\u6790\u65b9\u5f0f\u8c03\u6574\u3002\u8be5\u6587\u4e3b\u8981\u5c31CKD-aP\u7684\u53d1\u75c5\u673a\u5236\u53ca\u836f\u7269\u6cbb\u7597\u8fdb\u5c55\u4f5c\u4e00\u7efc\u8ff0\u3002\u5173\u952e\u8bcd \u80be\u900f\u6790\uff1b\u7619\u75d2\u75c7\uff1b\u836f\u7269\u7597\u6cd5\uff1b\u53d1\u75c5\u673a\u5236\u6162\u6027\u80be\u810f\u75c5\uff08chronic kidney disease\uff0cCKD\uff09\u662f\u5371\u5bb3\u4eba\u7c7b\u5065\u5eb7\u7684\u91cd\u8981\u516c\u5171\u536b\u751f\u95ee\u9898\uff0c\u5176\u4e2d\u90e8\u5206\u75c5\u4f8b\u8fdb\u5c55\u81f3\u7ec8\u672b\u671f\u80be\u75c5\uff08end-stage kidney disease\uff0cESKD\uff09\u3002\u8840\u6db2\u900f\u6790\uff08hemodialysis\uff0cHD\uff09\u662f\u6cbb\u7597ESKD\u7684\u4e3b\u8981\u65b9\u6cd5\u4e4b\u4e00\u3002HD\u60a3\u8005\u53ef\u51fa\u73b0\u5404\u79cd\u5e76\u53d1\u75c7\uff0c\u7619\u75d2\u75c7\u662f\u5176\u5e38\u89c1\u5e76\u53d1\u75c7\u4e4b\u4e00\uff0c\u65e2\u5f80\u88ab\u79f0\u4e3a\u5c3f\u6bd2\u75c7\u6027\u76ae\u80a4\u7619\u75d2\u75c7\uff08uremic pruritus\uff0cUP\uff09\u3002\u7531\u4e8e\u5c3f\u6bd2\u75c7\u4e25\u91cd\u7a0b\u5ea6\u4e0e\u7619\u75d2\u75c7\u4e25\u91cd\u7a0b\u5ea6\u5b58\u5728\u4e0d\u4e00\u81f4\u6027\uff0c\u73b0\u591a\u4f7f\u7528CKD\u76f8\u5173\u7619\u75d2\u75c7\uff08CKD-associated pruritus\uff0cCKD-aP\uff09\u7684\u6982\u5ff5\uff3b1\uff3d<\/sup>\u3002CKD-aP\u662f\u6307\u7ee7\u53d1\u4e8e\u80be\u810f\u75c5\u7684\u7619\u75d2\u75c7\uff0c\u4e3b\u8981\u8868\u73b0\u4e3a\u5c40\u90e8\u6216\u5168\u8eab\u76ae\u80a4\u4e0d\u540c\u7a0b\u5ea6\u7684\u7619\u75d2\uff0c\u4f34\u6216\u4e0d\u4f34\u6709\u76ae\u75b9\uff0c\u5448\u53d1\u4f5c\u6027\uff0c\u591c\u95f4\u8f83\u767d\u5929\u52a0\u91cd\uff0c\u53d1\u4f5c\u6301\u7eed\u65f6\u95f4\u4e0d\u7b49\uff3b1\uff3d<\/sup>\u3002\u7619\u75d2\u75c7\u53ef\u5f71\u54cdCKD\u60a3\u8005\u7684\u7761\u7720\u3001\u60c5\u7eea\u72b6\u6001\u3001\u793e\u4ea4\u529f\u80fd\uff0c\u5e76\u53ef\u5bfc\u81f4\u6291\u90c1\u751a\u81f3\u81ea\u6740\u503e\u5411\u4ee5\u53ca\u5fc3\u8840\u7ba1\u4e8b\u4ef6\u53d1\u751f\uff0c\u4e25\u91cd\u964d\u4f4e\u5176\u751f\u6d3b\u8d28\u91cf\uff0c\u5e76\u4e14CKD-aP\u4e5f\u662fHD\u60a3\u8005\u75c5\u6b7b\u7387\u7684\u72ec\u7acb\u9884\u6d4b\u56e0\u7d20\uff3b2\uff3d<\/sup>\u3002CKD-aP\u7684\u53d1\u75c5\u673a\u5236\u76ee\u524d\u5c1a\u4e0d\u660e\u786e\uff0c\u4e14\u4e34\u5e8a\u5b9e\u8df5\u4e2d\u6cbb\u7597\u6548\u679c\u6709\u9650\uff0c\u7ed9ESKD\u60a3\u8005\u548c\u533b\u62a4\u4eba\u5458\u90fd\u9020\u6210\u4e86\u8f83\u5927\u56f0\u6270\u3002\u672c\u6587\u805a\u7126HD\u60a3\u8005\u7619\u75d2\u75c7\uff0c\u7ed3\u5408\u56fd\u5185\u5916\u7814\u7a76\uff0c\u7efc\u5408\u9610\u8ff0CKD-aP\u7684\u53d1\u75c5\u673a\u5236\u53ca\u836f\u7269\u6cbb\u7597\u7684\u8fdb\u5c55\u3002<\/p>\n

\u4e00\u3001 \u6d41\u884c\u75c5\u5b66<\/h2>\n

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\u4e8c\u3001 \u53d1\u75c5\u673a\u5236<\/h2>\n

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\uff08\u4e00\uff09 \u514d\u75ab\u708e\u75c7\u5931\u8c03<\/h3>\n

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\uff08\u4e8c\uff09 \u5185\u6e90\u6027\u963f\u7247\u7c7b\u7cfb\u7edf\u5931\u8861<\/h3>\n

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\uff08\u4e09\uff09 \u4ee3\u8c22\u4ea7\u7269\u5f02\u5e38\u84c4\u79ef<\/h3>\n

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\u4e09\u3001 \u8bc4\u4f30<\/h2>\n

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\u56db\u3001 \u6cbb\u7597\u8fdb\u5c55<\/h2>\n

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\uff08\u4e00\uff09 \u836f\u7269\u6cbb\u7597<\/h3>\n

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\uff08\u4e09\uff09 \u8c03\u6574\u900f\u6790\u65b9\u5f0f<\/h3>\n

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\uff08\u56db\uff09 \u80be\u79fb\u690d<\/h3>\n

\u80be\u79fb\u690d\u662fESKD\u60a3\u8005\u6cbb\u7597\u7684\u6700\u4f18\u7b56\u7565\uff0c\u4e5f\u662f\u7f13\u89e3CKD-aP\u60a3\u8005\u75c7\u72b6\u7684\u6709\u6548\u624b\u6bb5\u3002\u65e9\u57281986\u5e74\uff0cAltmeyer\u7b49\uff3b59\uff3d<\/sup>\u8bc1\u5b9e\u4e86\u8be5\u7ed3\u8bba\uff0c\u6240\u6709\u80be\u79fb\u690d\u540e\u7684\u60a3\u8005\u7619\u75d2\u75c7\u8fbe\u5230\u5b8c\u5168\u6d88\u5931\uff0c\u5c3d\u7ba1\u7ed3\u679c\u4ee4\u4eba\u9f13\u821e\uff0c\u4f46\u8be5\u7814\u7a76\u6837\u672c\u91cf\u5c0f\u4e14\u53ea\u8003\u8651\u4e86\u5168\u8eab\u7619\u75d2\uff0c\u5b58\u5728\u4e00\u5b9a\u5c40\u9650\u6027\u3002\u8fd1\u5e74\u6765\u591a\u9879\u7814\u7a76\u7ed3\u679c\u90fd\u8868\u660e\u80be\u79fb\u690d\u786e\u5b9e\u53ef\u4e0d\u540c\u7a0b\u5ea6\u5730\u6539\u5584CKD-aP\u3002Taylor\u7b49\uff3b18\uff3d<\/sup>\u5728521\u4f8b\u80be\u79fb\u690d\u53d7\u8005\u4e2d\u8fdb\u884c\u7684\u524d\u77bb\u6027\u7814\u7a76\u663e\u793a\uff0c\u5728\u63a5\u53d7\u80be\u79fb\u690d\u540e\u76843\u4e2a\u6708\uff0c23%\u60a3\u8005\u7619\u75d2\u75c7\u5f97\u5230\u6539\u5584\u3002Krajewski\u7b49\uff3b17\uff3d<\/sup>\u5bf9197\u4f8b\u80be\u79fb\u690d\u60a3\u8005\u5728\u79fb\u690d\u524d\u540e\u7684\u7619\u75d2\u75c7\u8fdb\u884c\u4e86\u5206\u6790\uff0c38.6%\uff0876\/197\uff09\u60a3\u8005\u5728\u900f\u6790\u671f\u95f4\u5b58\u5728\u7619\u75d2\u75c7\uff0c\u5176\u4e2d73.7%\uff0856\/76\uff09\u60a3\u8005\u5728\u63a5\u53d7\u80be\u79fb\u690d\u540e\u7619\u75d2\u75c7\u5f97\u5230\u5b8c\u5168\u7f13\u89e3\u3002\u7136\u800c\uff0c42\u4f8b\u80be\u79fb\u690d\u53d7\u8005\u4ecd\u5b58\u5728\u7619\u75d2\u75c7\uff0c\u5176\u4e2d52.4%\u662f\u5728\u80be\u79fb\u690d\u540e\u51fa\u73b0\u7684\uff3b17\uff3d<\/sup>\u3002\u4e00\u9879\u968f\u8bbf\u65f6\u95f4\u957f\u8fbe5\u5e74\u7684\u7eb5\u5411\u7814\u7a76\u663e\u793a\uff0c\u80be\u79fb\u690d\u540e\u60a3\u8005\u7619\u75d2\u75c7\u53ca\u808c\u8089\u75c9\u631b\u7684\u6539\u5584\u6700\u4e3a\u663e\u8457\uff3b60\uff3d<\/sup>\u3002<\/p>\n

\u4e94\u3001 \u603b\u7ed3<\/h2>\n

\u5c3d\u7ba1CKD-aP\u4e0eCKD\u60a3\u8005\u5c24\u5176\u662fHD\u60a3\u8005\u7684\u751f\u6d3b\u8d28\u91cf\u53ca\u8fdc\u671f\u75c5\u6b7b\u7387\u660e\u663e\u76f8\u5173\uff0c\u4f46CKD-aP\u4ecd\u7136\u88ab\u4f4e\u4f30\uff0c\u53d1\u75c5\u673a\u5236\u5c1a\u672a\u5b8c\u5168\u9610\u660e\uff0c\u4e14\u7279\u6548\u7684\u6cbb\u7597\u63aa\u65bd\u6709\u9650\u3002\u6b64\u5916\uff0c\u76ee\u524d\u5bf9CKD-aP\u6cbb\u7597\u7684\u7814\u7a76\u4e3b\u8981\u5173\u6ce8\u5728\u5355\u4e00\u6cbb\u7597\u63aa\u65bd\u5bf9\u7619\u75d2\u75c7\u7684\u6539\u5584\uff0c\u4f46CKD-aP\u4e0d\u4ec5\u662f\u5355\u7eaf\u7684\u7619\u75d2\uff0c\u8fd8\u4f1a\u5bfc\u81f4\u7761\u7720\u8d28\u91cf\u4e0b\u964d\u3001\u6291\u90c1\u3001\u611f\u67d3\u7b49\u4e00\u7cfb\u5217\u5e76\u53d1\u75c7\uff0c\u5bf9CKD-aP\u7684\u6709\u6548\u6cbb\u7597\u4e0d\u4ec5\u5e94\u6539\u5584\u7619\u75d2\u75c7\uff0c\u540c\u65f6\u9700\u8981\u5173\u6ce8\u5bf9\u5176\u4ed6\u5e76\u53d1\u75c7\u7684\u5f71\u54cd\u3002\u963f\u7247\u7c7b\u53d7\u4f53\u6fc0\u52a8\u5242\/\u62ee\u6297\u5242\u5728\u5927\u578b\u968f\u673a\u5bf9\u7167\u8bd5\u9a8c\u4e2d\u663e\u793a\u51fa\u663e\u8457\u7597\u6548\uff0c\u6709\u671b\u6210\u4e3aHD\u60a3\u8005\u7619\u75d2\u75c7\u7684\u6cbb\u7597\u9009\u62e9\u3002<\/p>\n

\u5229\u76ca\u51b2\u7a81\u58f0\u660e<\/h2>\n

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\u5f15\u7528\u672c\u6587\uff1a \u6c64\u6653\u9759, \u6885\u957f\u6797. \u8840\u6db2\u900f\u6790\u60a3\u8005\u7619\u75d2\u75c7\u7684\u53d1\u75c5\u673a\u5236\u53ca\u836f\u7269\u6cbb\u7597\u8fdb\u5c55[J]. \u4e2d\u534e\u80be\u810f\u75c5\u6742\u5fd7, 2024, 40(1): 61-66. DOI: 10.3760\/cma.j.cn441217-20230413-00420.<\/p>\n

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