\u901a\u4fe1\u4f5c\u8005\uff1a\u9648\u709c\u6559\u6388<\/p>\n<\/p>\n
\u95eb\u52a0\u8273\u6559\u6388<\/p>\n
\u3010\u5f15\u7528\u672c\u6587\u3011\u95eb\u52a0\u8273\uff0c\u8d75 \u8d8a\uff0c\u9648 \u709c. \u56fd\u9645\u300a\u80c6\u56ca\u5207\u9664\u672f\u4e2d\u9884\u9632\u80c6\u7ba1\u635f\u4f24\u591a\u534f\u4f1a\u5171\u8bc6\u548c\u5b9e\u8df5\u6307\u5357\uff082020\uff09\u300b\u89e3\u8bfb[J]. \u4e2d\u56fd\u5b9e\u7528\u5916\u79d1\u6742\u5fd7,2020,40(12):1391-1395,1400.<\/p>\n
\u56fd\u9645\u300a\u80c6\u56ca\u5207\u9664\u672f\u4e2d\u9884\u9632\u80c6\u7ba1\u635f\u4f24\u591a\u534f\u4f1a\u5171\u8bc6<\/p>\n
\u548c\u5b9e\u8df5\u6307\u5357\uff082020\uff09\u300b\u89e3\u8bfb<\/p>\n
\u95eb\u52a0\u8273\uff0c\u8d75 \u8d8a\uff0c\u9648 \u709c<\/p>\n
\u4e2d\u56fd\u5b9e\u7528\u5916\u79d1\u6742\u5fd7,2020,40(12):1391-1395,1400<\/p>\n
\u6458\u8981 <\/p>\n
\u533b\u6e90\u6027\u80c6\u7ba1\u635f\u4f24\u662f\u8179\u8154\u955c\u80c6\u56ca\u5207\u9664\u672f\u6700\u5e38\u89c1\u7684\u4e25\u91cd\u5e76\u53d1\u75c7\uff0c\u662f\u533b\u7597\u8d39\u7528\u589e\u52a0\u3001\u75c5\u4eba\u751f\u6d3b\u8d28\u91cf\u4e0b\u964d\u548c\u5f15\u8d77\u533b\u7597\u7ea0\u7eb7\u7684\u91cd\u8981\u539f\u56e0\u3002\u4f18\u5316\u80c6\u56ca\u5207\u9664\u672f\u89e3\u5256\u8fa8\u8bc6\u6280\u672f\u548c\u624b\u672f\u6280\u80fd\u3001\u98ce\u9669\u8bc4\u4f30\u548c\u63a7\u5236\u3001\u80c6\u7ba1\u635f\u4f24\u5904\u7406\u7b56\u7565\u548c\u63d0\u5347\u533b\u751f\u7ecf\u9a8c\u7b49\u73af\u8282\uff0c\u6709\u53ef\u80fd\u964d\u4f4e\u533b\u6e90\u6027\u80c6\u7ba1\u635f\u4f24\u7684\u53d1\u751f\u7387\u30022018\u5e7410\u6708\u7f8e\u56fd\u80c3\u80a0\u4e0e\u5185\u955c\u5916\u79d1\u533b\u5e08\u534f\u4f1a\uff08SAGES\uff09\u8054\u5408\u7f8e\u56fd\u809d\u80c6\u80f0\u534f\u4f1a\u3001\u56fd\u9645\u809d\u80c6\u80f0\u534f\u4f1a\u3001\u6d88\u5316\u9053\u5916\u79d1\u534f\u4f1a\u548c\u6b27\u6d32\u5185\u955c\u5916\u79d1\u534f\u4f1a\u7ec4\u6210\u7684\u56fd\u9645\u5c0f\u7ec4\uff0c\u9488\u5bf918\u4e2a\u57fa\u4e8e\u8bc1\u636e\u7684\u95ee\u9898\u548c\u63a8\u8350\u610f\u89c1\u8fdb\u884c\u6295\u7968\u51b3\u8bae\uff0c\u901a\u8fc7\u4e86\u5176\u4e2d17\u4e2a\u63a8\u8350\u610f\u89c1\u3002\u8be5\u6307\u5357\u53ef\u4e3a\u5916\u79d1\u533b\u751f\u7684\u4e34\u5e8a\u5b9e\u8df5\u63d0\u4f9b\u6307\u5bfc\uff0c\u4e3a\u76f8\u5173\u533b\u7597\u57f9\u8bad\u673a\u6784\u3001\u533b\u9662\u7ba1\u7406\u548c\u4e13\u4e1a\u534f\u4f1a\u7b49\u63d0\u4f9b\u5408\u7406\u6709\u6548\u7684\u89c4\u8303\u4ee5\u964d\u4f4e\u80c6\u7ba1\u635f\u4f24\u53d1\u751f\u7387\uff0c\u4ece\u800c\u6539\u5584\u75c5\u4eba\u7684\u9884\u540e\u3002<\/p>\n
\u57fa\u91d1\u9879\u76ee\uff1a\u56fd\u5bb6\u81ea\u7136\u79d1\u5b66\u57fa\u91d1\u9879\u76ee\uff08No. 81570545\uff09\uff1b\u4e0a\u6d77\u4ea4\u901a\u5927\u5b66\u201c\u533b\u5de5\u4ea4\u53c9\u57fa\u91d1\u201d\u9879\u76ee\uff08No.YG2014MS46\uff09<\/p>\n
\u4f5c\u8005\u5355\u4f4d\uff1a1\u4e0a\u6d77\u4ea4\u901a\u5927\u5b66\u533b\u5b66\u9662\u9644\u5c5e\u4ec1\u6d4e\u533b\u9662\u80c6\u80f0\u5916\u79d1\uff0c\u4e0a\u6d77200011\uff1b2\u5fb7\u56fd\u79d1\u9686\u5927\u5b66\u9644\u5c5e\u533b\u9662\u666e\u5916\u79d1\u3001\u5185\u810f\uff0c\u80bf\u7624\u4e0e\u79fb\u690d\u5916\u79d1<\/p>\n
\u901a\u4fe1\u4f5c\u8005\uff1a\u9648\u709c\uff0cE-mail\uff1achensurg@aliyun.com<\/p>\n
\u8179\u8154\u955c\u80c6\u56ca\u5207\u9664\u672f\uff08LC\uff09\u4f5c\u4e3a\u4e00\u79cd\u5e38\u89c4\u7684\u5fae\u521b\u624b\u672f\uff0c\u8fdb\u5165\u4e34\u5e8a\u5b9e\u8df5\u4e0d\u4e45\uff0c\u4fbf\u8fc5\u901f\u6210\u4e3a\u80c6\u56ca\u5207\u9664\u672f\u7684\u6807\u51c6\u624b\u672f\u65b9\u5f0f\u3002\u7136\u800cLC\u7684\u5927\u91cf\u5f00\u5c55\u4e5f\u5e26\u6765\u4e86\u8f83\u9ad8\u7684\u80c6\u7ba1\u635f\u4f24\u53d1\u751f\u7387\u3002\u4ece2014\u5e74\u8d77\uff0c\u7f8e\u56fd\u80c3\u80a0\u4e0e\u5185\u955c\u5916\u79d1\u533b\u5e08\u534f\u4f1a\uff08SAGES\uff09\u4e3a\u52aa\u529b\u63d0\u9ad8\u80c6\u56ca\u5207\u9664\u5b89\u5168\u6027\u548c\u964d\u4f4e\u80c6\u7ba1\u635f\u4f24\u53d1\u751f\u7387\uff0c\u8054\u5408\u7f8e\u56fd\u809d\u80c6\u80f0\u534f\u4f1a\u3001\u56fd\u9645\u809d\u80c6\u80f0\u534f\u4f1a\u3001\u6d88\u5316\u9053\u5916\u79d1\u534f\u4f1a\u548c\u6b27\u6d32\u5185\u955c\u5916\u79d1\u534f\u4f1a\u5c3118\u4e2a\u80c6\u56ca\u5207\u9664\u672f\u80c6\u7ba1\u635f\u4f24\u76f8\u5173\u7684\u5173\u952e\u95ee\u9898\u8fdb\u884c\u4e86\u5168\u9762\u7684\u6587\u732e\u56de\u987e\uff0c\u5236\u5b9a\u4e86\u57fa\u4e8e\u8bc1\u636e\u7684\u63a8\u8350\u610f\u89c1\uff0c\u5e76\u4e8e2018\u5e7410\u6708\u5728\u6ce2\u58eb\u987f\u53ec\u5f00\u4f1a\u8bae\uff0c\u5ba1\u6838\u548c\u901a\u8fc7\u4e86\u63a8\u8350\u610f\u89c1\uff0c\u5236\u5b9a\u4e86\u300a\u80c6\u56ca\u5207\u9664\u672f\u4e2d\u9884\u9632\u80c6\u7ba1\u635f\u4f24\u591a\u534f\u4f1a\u5171\u8bc6\u548c\u5b9e\u8df5\u6307\u5357\uff082020\uff09\u300b\uff3b1\uff3d\uff08\u4ee5\u4e0b\u7b80\u79f0\u201c\u6307\u5357\u201d\uff09\u3002\u672c\u6587\u7ed3\u5408\u56fd\u5185\u4e34\u5e8a\u8bca\u6cbb\u7ecf\u9a8c\u548c\u533b\u7597\u73b0\u72b6\u5bf9\u8be5\u6307\u5357\u89c2\u70b9\u8fdb\u884c\u89e3\u8bfb\u30021 \u6307\u5357\u8303\u56f4\u3001\u76ee\u7684\u548c\u65b9\u6cd5\u6307\u5357\u660e\u786e\u4e86\u80c6\u56ca\u5207\u9664\u672f\u4e2d\u907f\u514d\u80c6\u7ba1\u635f\u4f24\u7684\u6700\u4f73\u65b9\u6cd5\uff0c\u5236\u5b9a\u548c\u63a8\u5e7f\u57fa\u4e8e\u5faa\u8bc1\u533b\u5b66\u8bc1\u636e\u7684\u63d0\u9ad8\u80c6\u56ca\u5207\u9664\u5b89\u5168\u6027\u7684\u5b9e\u8df5\u63a8\u8350\u610f\u89c1\uff0c\u9762\u5411\u666e\u5916\u79d1\u533b\u751f\u3001\u809d\u80c6\u5916\u79d1\u533b\u751f\u548c\u5b9e\u4e60\u533b\u751f\uff0c\u6db5\u76d6\u89e3\u5256\u8fa8\u8bc6\u6280\u5de7\u3001\u53d1\u75c5\u56e0\u7d20\u3001\u64cd\u4f5c\u6280\u5de7\u3001\u533b\u751f\u57f9\u8bad\u548c\u672f\u4e2d\u635f\u4f24\u5904\u7406\u7b49\u591a\u9879\u5171\u8bc6\u3002\u8be5\u6307\u5357\u7684\u5e94\u7528\u65e8\u5728\u63d0\u9ad8\u80c6\u56ca\u5207\u9664\u8fc7\u7a0b\u4e2d\u5916\u79d1\u5904\u7406\u7684\u53ef\u63a7\u6027\uff0c\u964d\u4f4e\u80c6\u7ba1\u635f\u4f24\u98ce\u9669\u548c\u76f8\u5173\u53d1\u751f\u7387\uff0c\u63a7\u5236\u533b\u7597\u8d39\u7528\u548c\u6539\u5584\u75c5\u4eba\u751f\u6d3b\u8d28\u91cf\u3002<\/p>\n
\u8be5\u6307\u5357\u6d89\u53ca\u80c6\u56ca\u5207\u9664\u672f\u80c6\u7ba1\u635f\u4f24\u76f8\u5173\u768418\u4e2a\u5173\u952e\u95ee\u9898\uff08\u5982\u88681\uff09\u3002<\/p>\n<\/p>\n
2 \u89e3\u5256\u8fa8\u8bc6\u6280\u5de7<\/p>\n
2.1 LC\u4e2d\u5173\u952e\u5b89\u5168\u89c6\u91ce\uff08CVS\uff09\u7684\u5fc5\u8981\u6027 \u6307\u5357\u5236\u5b9a\u5c0f\u7ec4\uff08GDG\uff09\u8ba4\u4e3a\u5916\u79d1\u533b\u751f\u5728\u65bd\u884cLC\u624b\u672f\u65f6\uff0c\u5e94\u4f7f\u7528CVS\u6280\u672f\u8fa8\u8bc6\u80c6\u56ca\u7ba1\u548c\u80c6\u56ca\u52a8\u8109\uff08\u4e13\u5bb6\u5171\u8bc6\uff09\u3002\u76ee\u524d\u53ea\u6709\u95f4\u63a5\u8bc1\u636e\u652f\u6301CVS\u6280\u672f\u7684\u4f7f\u7528\u3002\u901a\u8fc7\u7eb3\u5165\u6837\u672c\u91cf\u2265400\u4f8b\u7684\u961f\u5217\u7814\u7a76\u8fdb\u884cMeta\u5206\u6790\uff0c\u5e94\u7528CVS\u6280\u672f\u7684\u80c6\u7ba1\u635f\u4f24\u53d1\u751f\u7387\u4e3a2\/100\u4e07\uff0c\u4f4e\u4e8e\u5e94\u7528\u58f6\u8179\u90e8\u6280\u672f\u76841.5\/1000\u53d1\u751f\u7387 \uff3b2-8\uff3d\u3002\u56e0\u4e3a\u4e24\u7ec4\u6837\u672c\u5b58\u5728\u9ad8\u5ea6\u504f\u501a\u7684\u53ef\u80fd\uff0c\u6240\u4ee5\u4e0a\u8ff0\u7ed3\u679c\u7684\u53ef\u9760\u6027\u6709\u5f85\u8003\u8bc1\u3002CVS\u6280\u672f\u6613\u4e8e\u64cd\u4f5c\uff0c\u572885%\uff5e95%\u7684\u75c5\u4f8b\u4e2d\u83b7\u5f97\u6210\u529f\uff0c\u4e14\u80c6\u7ba1\u635f\u4f24\u901a\u5e38\u53d1\u751f\u4e8eCVS\u6280\u672f\u4e0d\u80fd\u5e94\u7528\u7684\u75c5\u4f8b\uff0c\u800c\u4e14\u6ca1\u6709\u5b9e\u8d28\u7684\u8bc1\u636e\u8868\u660e\u5c1d\u8bd5CVS\u6280\u672f\u4f1a\u5e26\u6765\u8d1f\u9762\u7684\u4e34\u5e8a\u6548\u679c\u3002\u57fa\u4e8e\u4ee5\u4e0a\u4e8b\u5b9e\u8bc1\u636e\uff0cGDG\u4f5c\u51fa\u4e86\u8be5\u63a8\u8350\u6027\u610f\u89c1\uff3b2-4\uff3d\u3002\u540c\u65f6\uff0c\u57fa\u4e8e\u5b9e\u8df5\u7ecf\u9a8c\uff0c\u5efa\u8bae\u5916\u79d1\u533b\u751f\u5728LC\u4e2d\u79bb\u65ad\u8109\u7ba1\u7ed3\u6784\u524d\u7a0d\u4f5c\u505c\u987f\uff0c\u4ee5\u786e\u8ba4\u662f\u5426\u8fbe\u5230CVS\u6807\u51c6\uff08\u4e13\u5bb6\u5171\u8bc6\uff09\u3002\u5c3d\u7ba1CVS\u6280\u672f\u7684\u63d0\u51fa\u548c\u4e34\u5e8a\u5e94\u7528\u5df2\u670920\u5e74\u4f59\uff0c\u56fd\u9645\u4e0a\u5df2\u5f00\u5c55\u4e86\u4e0d\u5c11\u5173\u4e8eCVS\u6280\u672f\u7684\u4e34\u5e8a\u5b9e\u8df5\u548c\u7814\u7a76\uff0c\u4f46\u76ee\u524d\u56fd\u5185\u7684\u5916\u79d1\u533b\u751f\u5bf9CVS\u6280\u672f\u7684\u8ba4\u77e5\u548c\u5e94\u7528\u4ecd\u8f83\u4e3a\u964c\u751f\uff0c\u5e0c\u671b\u4e0d\u4e45\u7684\u672a\u6765\u56fd\u5185\u4e30\u5bcc\u7684\u75c5\u4f8b\u8d44\u6e90\u548c\u4e25\u8c28\u7684\u4e34\u5e8a\u7814\u7a76\u8bbe\u8ba1\u80fd\u4e3aCVS\u6280\u672f\u7684\u63a8\u5e7f\u548c\u5e94\u7528\u63d0\u4f9b\u66f4\u9ad8\u7ea7\u522b\u7684\u4e34\u5e8a\u533b\u5b66\u8bc1\u636e\u3002<\/p>\n
\u6307\u5357\u5efa\u8bae\u5728\u5173\u4e8eLC\u7684\u524d\u77bb\u6027\u7814\u7a76\u4e2d\u878d\u5165\u201c\u5173\u952e\u89c6\u91ce\u6682\u65f6\u505c\u7559\u201d\u8fd9\u4e00\u7814\u7a76\u8981\u7d20\u3002<\/p>\n
2.2 CVS\u65e0\u6cd5\u83b7\u53d6\u65f6\u7684\u624b\u672f\u65b9\u6cd5 \u5f53\u708e\u75c7\u963b\u788d\u4e86\u5e94\u7528CVS\u6280\u672f\u65f6\u7684\u89e3\u5256\u8fa8\u8bc6\u65f6\uff0c\u907f\u514d\u89e3\u5256\u7ba1\u9053\u7ed3\u6784\u80fd\u9884\u671f\u964d\u4f4e\u533b\u6e90\u6027\u80c6\u7ba1\u635f\u4f24\u7684\u53d1\u751f\u98ce\u9669\u3002\u7efc\u5408\u76f8\u5173\u7814\u7a76\uff0cGDG\u8ba4\u4e3a\uff0c\u5f53\u708e\u75c7\u963b\u788d\u4e86\u501f\u52a9CVS\u6280\u672f\u6216\u5f71\u50cf\u6280\u672f\u6765\u8fa8\u8bc6\u89e3\u5256\uff0c\u7531\u4e8e\u80c6\u56ca\u5927\u90e8\u5207\u9664\u672f\uff08STC\uff09\u5e76\u4e0d\u6d89\u53ca\u80c6\u56ca\u4e09\u89d2\u7684\u89e3\u5256\uff0c\u624b\u672f\u5b89\u5168\u6027\u8981\u9ad8\u4e8e\u80c6\u56ca\u5b8c\u6574\u5207\u9664\u3002\u5e76\u4e14\uff0cSTC\u548c\u80c6\u56ca\u5e95\u4f18\u5148\u663e\u9732\u6280\u672f\u7684\u6982\u5ff5\u5e76\u4e0d\u77db\u76fe\u3002\u82e5\u80c6\u56ca\u4e09\u89d2\u65e0\u6cd5\u89e3\u5256\uff0c\u53ef\u4ee5\u901a\u8fc7STC\u6216\u80c6\u56ca\u5e95\u4f18\u5148\u663e\u9732\u6280\u672f\u6765\u907f\u514d\u89e3\u5256\u80c6\u56ca\u4e09\u89d2\uff0c\u4ece\u800c\u4f7f\u80c6\u7ba1\u635f\u4f24\u7684\u98ce\u9669\u6700\u5c0f\u5316\u3002\u56e0\u800c\uff0c\u5f53\u80c6\u56ca\u5207\u9664\u672f\u4e2d\u4e0d\u80fd\u5e94\u7528CVS\u6280\u672f\u4e14\u80c6\u9053\u7684\u6b63\u786e\u89e3\u5256\u4e0d\u80fd\u4f9d\u9760\u5176\u4ed6\u65b9\u6cd5\u5982IOC\u83b7\u5f97\u65f6\uff0c\u5efa\u8bae\u5916\u79d1\u533b\u751f\u4f18\u5148\u8003\u8651\u884c\u80c6\u56ca\u5927\u90e8\u5207\u9664\u800c\u975e\u80c6\u56ca\u6574\u4f53\u5207\u9664\u672f\uff08\u4e13\u5bb6\u5171\u8bc6\uff09\u3002 <\/p>\n
3 \u5f71\u50cf\u5b66\u624b\u6bb5<\/p>\n
3.1 \u672f\u4e2d\u80c6\u9053\u5f71\u50cf\u6280\u672f\u5e94\u7528\u7684\u5fc5\u8981\u6027 \u76ee\u524d\u652f\u6301LC\u4e2d\u4f7f\u7528\u672f\u4e2d\u80c6\u9053\u5f71\u50cf\u6280\u672f\u7684\u7814\u7a76\u8bc1\u636e\u7ea7\u522b\u5e76\u4e0d\u662f\u592a\u9ad8\u3002\u901a\u8fc7Meta\u5206\u6790\u7eb3\u516514\u9879\u7814\u7a76\uff082 540 700\u4f8b\u80c6\u56ca\u5207\u9664\u672f\uff09\u53d1\u73b0\uff0cLC\u4e2d\u4f7f\u7528\u672f\u4e2d\u80c6\u9053\u9020\u5f71\uff08IOC\uff09\u80fd\u591f\u964d\u4f4e\u80c6\u7ba1\u635f\u4f24\u7684\u53d1\u751f\u7387\uff08OR 0.78\uff0cP\uff1c0.0001\uff09\uff3b1\uff3d\u3002\u57fa\u4e8e\u745e\u5178\u56fd\u5bb6\u80c6\u56ca\u7ed3\u77f3\u624b\u672f\u5927\u6570\u636e\uff0851 041\u4f8b\u80c6\u56ca\u5207\u9664\u672f\uff09\u5206\u6790\u53d1\u73b0\uff0c\u4f7f\u7528IOC\u80fd\u964d\u4f4e\u6025\u6027\u80c6\u56ca\u708e\u75c5\u4eba\uff08OR 0.44\uff0c95%CI 0.30\uff5e0.63\uff09\u6216\u6709\u6025\u6027\u80c6\u56ca\u708e\u75c5\u53f2\u75c5\u4eba\uff08OR 0.59\uff0c95%CI 0.35\uff5e1.00\uff09\u80c6\u7ba1\u635f\u4f24\u7684\u53d1\u751f\u7387\uff3b9\uff3d\u3002\u901a\u8fc7\u5bf98\u9879\u7814\u7a76\uff081256\u4f8b\u80c6\u7ba1\u635f\u4f24\u75c5\u4eba\uff09\u7684Meta\u5206\u6790\u53d1\u73b0\uff0c\u4f7f\u7528IOC\u66f4\u6613\u5728\u672f\u4e2d\u53d1\u73b0\u80c6\u7ba1\u635f\u4f24\uff08OR 2.92\uff0cP=0.014\uff09\uff3b1\uff3d\u3002\u56e0\u800c\uff0cGDG\u8ba4\u4e3a\uff0c\u5bf9\u4e8e\u6025\u6027\u80c6\u56ca\u708e\u75c5\u4eba\u6216\u6709\u6025\u6027\u80c6\u56ca\u708e\u75c5\u53f2\u7684\u75c5\u4eba\uff0c\u5efa\u8baeLC\u4e2d\u4f7f\u7528IOC\u4ee5\u964d\u4f4e\u80c6\u7ba1\u635f\u4f24\u7684\u98ce\u9669\uff08\u6761\u4ef6\u6027\u63a8\u8350\uff0c\u786e\u5b9a\u6027\u8bc1\u636e\u975e\u5e38\u4f4e\uff09\u3002\u5177\u6709\u4e00\u5b9a\u624b\u672f\u7ecf\u9a8c\u548c\u57f9\u8bad\u7ecf\u5386\u7684\u5916\u79d1\u533b\u751f\u53ef\u5728LC\u4e2d\u4ee5\u8179\u8154\u955c\u8d85\u58f0\u5f71\u50cf\u66ff\u4ee3IOC\u3002\u5982\u679cLC\u4e2d\u80c6\u9053\u89e3\u5256\u4e0d\u6e05\u6670\u6216\u6000\u7591\u53d1\u751f\u80c6\u7ba1\u635f\u4f24\uff0c\u5efa\u8bae\u5916\u79d1\u533b\u751f\u4f7f\u7528\u672f\u4e2d\u80c6\u9053\u5f71\u50cf\u6280\u672f\uff08\u5c24\u5176\u662fIOC\uff09\u4ee5\u964d\u4f4e\u80c6\u7ba1\u635f\u4f24\u7684\u98ce\u9669\uff08\u5f3a\u70c8\u63a8\u8350\uff0c\u786e\u5b9a\u6027\u8bc1\u636e\u975e\u5e38\u4f4e\uff09\u3002\u7ed3\u5408\u56fd\u5185\u533b\u7597\u73b0\u72b6\uff0c\u5bf9\u4e8e\u6025\u6027\u80c6\u56ca\u708e\u75c5\u4eba\u6216\u6709\u6025\u6027\u80c6\u56ca\u708e\u75c5\u53f2\u7684\u75c5\u4eba\u5c24\u5176\u662f\u80c6\u56ca\u4e09\u89d2\u89e3\u5256\u4e0d\u6e05\u8005\uff0c\u7b14\u8005\u5efa\u8bae\u56fd\u5185\u6709\u6761\u4ef6\u7684\u533b\u7597\u4e2d\u5fc3\u5c3d\u91cf\u5728LC\u672f\u4e2d\u5e94\u7528\u80c6\u9053\u5f71\u50cf\u6280\u672f\u8fdb\u884c\u80c6\u9053\u89e3\u5256\u8fa8\u8bc6\u4ee5\u964d\u4f4e\u80c6\u7ba1\u635f\u4f24\u7684\u98ce\u9669\u3002\u81f3\u4e8e\u5e94\u4f7f\u7528\u8fd1\u7ea2\u5916\uff08NIR\uff09\u80c6\u9053\u663e\u5f71\u8fd8\u662fIOC\u4ee5\u964d\u4f4e\u80c6\u7ba1\u635f\u4f24\u7684\u53d1\u751f\u98ce\u9669\u6216\u7a0b\u5ea6\uff0c\u76f8\u5173\u5bf9\u6bd4\u6027\u8bc1\u636e\u4e0d\u8db3\u4ee5\u4f5c\u51fa\u76f8\u5e94\u7684\u63a8\u8350\u610f\u89c1\u3002<\/p>\n
3.2 \u672f\u4e2dNIR\u663e\u5f71\u7684\u5fc5\u8981\u6027 LC\u672f\u4e2d\u5e38\u89c4\u4f7f\u7528\u767d\u5149\u5f71\u50cf\u8fdb\u884c\u89e3\u5256\u8fa8\u8bc6\uff0c\u4f46\u5728\u6b64\u57fa\u7840\u4e4b\u4e0a\u662f\u5426\u5e94\u8be5\u4f7f\u7528NIR\u663e\u5f71\u4ee5\u964d\u4f4e\u80c6\u7ba1\u635f\u4f24\u7684\u98ce\u9669\u662f\u8f83\u4e3a\u5b9e\u9645\u7684\u4e34\u5e8a\u95ee\u9898\u3002\u76ee\u524d\u5e76\u6ca1\u6709\u4e3aLC\u4e2d\u5f71\u50cf\u624b\u6bb5\u5f71\u54cd\u80c6\u7ba1\u635f\u4f24\u6216\u5176\u4ed6\u7ed3\u5c40\u7684\u53d1\u751f\u98ce\u9669\u63d0\u4f9b\u76f4\u63a5\u8bc1\u636e\u7684\u7814\u7a76\u3002\u4e00\u9879\u5355\u76f2\u3001\u591a\u4e2d\u5fc3\u7684RCT\u7814\u7a76\uff0c\u5bf9\u6bd4LC\u4e2d\u5e94\u7528NIR\u663e\u5f71\u7ed3\u5408\u767d\u5149\u663e\u5f71\uff08321\u4f8b\uff09\u548c\u5355\u72ec\u767d\u5149\u663e\u5f71\uff08318\u4f8b\uff09\u8fa8\u8bc67\u79cd\u80c6\u9053\u7ed3\u6784\uff08\u80c6\u56ca\u7ba1\u3001\u53f3\u809d\u7ba1\u3001\u809d\u603b\u7ba1\u3001\u80c6\u603b\u7ba1\u3001\u80c6\u56ca-\u80c6\u603b\u7ba1\u6c47\u5408\u90e8\u3001\u80c6\u56ca\u7ba1-\u80c6\u56ca\u6c47\u5408\u90e8\u548c\u526f\u809d\u7ba1\uff09\u7684\u6548\u679c\u53d1\u73b0\uff0c\u89e3\u5256\u80c6\u56ca\u4e09\u89d2\u524d\uff0c\u8054\u5408\u7ec4\u5bf9\u6bcf\u79cd\u80c6\u9053\u7ed3\u6784\u7684\u53d1\u73b0\u7387\u5747\u660e\u663e\u9ad8\u4e8e\u5355\u72ec\u767d\u5149\u663e\u5f71\u7ec4\uff0cOR\u503c\u4ecb\u4e8e\u80c6\u56ca\u7ba1-\u80c6\u56ca\u6c47\u5408\u90e8\u5bf9\u5e94\u76842.3\uff0895% CI 1.6\uff5e3.2\uff09\u5230\u53f3\u809d\u7ba1\u5bf9\u5e94\u76843.6\uff0895% CI 1.6\uff5e9.3\uff09\uff0c\u800c\u89e3\u5256\u80c6\u56ca\u4e09\u89d2\u540e\uff0c\u9664\u80c6\u56ca\u7ba1\u548c\u80c6\u56ca\u7ba1-\u80c6\u56ca\u8fde\u63a5\u90e8\u5916\uff0c\u8054\u5408\u7ec4\u5bf9\u5176\u4ed6\u80c6\u9053\u7ed3\u6784\u8fa8\u8bc6\u7387\u5747\u660e\u663e\u9ad8\u4e8e\u5355\u72ec\u767d\u5149\u663e\u5f71\u7ec4\uff3b10\uff3d\u3002\u4e13\u5bb6\u5efa\u8bae\u5c06NIR\u663e\u5f71\u89c6\u4e3a\u767d\u5149\u5f71\u50cf\u7684\u8f85\u52a9\u5de5\u5177\uff0c\u8fdb\u884c\u80c6\u56ca\u5207\u9664\u672f\u4e2d\u80c6\u9053\u89e3\u5256\u7684\u8fa8\u8bc6\uff08\u6761\u4ef6\u6027\u63a8\u8350\uff0c\u786e\u5b9a\u6027\u8bc1\u636e\u975e\u5e38\u4f4e\uff09\u3002\u4f46\u662fGDG\u7279\u522b\u6307\u51fa\uff0cNIR\u663e\u5f71\u5e76\u4e0d\u80fd\u53d6\u4ee3\u7cbe\u7ec6\u7684\u89e3\u5256\uff08\u4e13\u5bb6\u5171\u8bc6\uff09\u3002<\/p>\n
NIR\u80c6\u9053\u663e\u5f71\u3001\u5355\u72ec\u767d\u5149\u663e\u5f71\u53caIOC\u7684\u6548\u679c\u5bf9\u6bd4\u8fd8\u9700\u8981\u5177\u6709\u98ce\u9669\u5206\u5c42\u548c\u98ce\u9669\u8c03\u6574\u7684\u5927\u578b\u4e34\u5e8a\u8bd5\u9a8c\u6765\u660e\u786e\u3002\u56e0\u80c6\u7ba1\u635f\u4f24\u5728\u8fd9\u7c7b\u7814\u7a76\u4e2d\u4e0d\u5e38\u89c1\uff0c\u5efa\u8bae\u7c7b\u4f3c\u4e34\u5e8a\u8bd5\u9a8c\u66f4\u591a\u5173\u6ce8\u5176\u4ed6\u6307\u6807\u5982\u7ba1\u9053\u7ed3\u6784\u7684\u8fa8\u8bc6\u3001CVS\u7684\u83b7\u53d6\u548c\u4e2d\u8f6c\u5f00\u8179\u7b49\uff0c\u7814\u7a76\u4eba\u7fa4\u5e94\u8be5\u9762\u5411\u6709\u6025\u6027\u80c6\u56ca\u708e\u53d1\u4f5c\u3001\u6025\u6027\u80c6\u56ca\u708e\u75c5\u53f2\u3001\u4e25\u91cd\u6162\u6027\u80c6\u56ca\u708e\u6216\u80a5\u80d6\u7b49\u590d\u6742\u60c5\u51b5\u7684\u80c6\u56ca\u5207\u9664\u75c5\u4eba\u3002<\/p>\n
4 \u80c6\u7ba1\u635f\u4f24\u98ce\u9669\u8bc4\u4f30\u867d\u7136\u76ee\u524d\u6709\u8bb8\u591a\u9884\u540e\u98ce\u9669\u76f8\u5173\u6027\u7684\u7814\u7a76\uff0c\u4f46\u8fd9\u4e9b\u7814\u7a76\u5e76\u672a\u8bc4\u4f30\u4f7f\u7528\u8fd9\u4e9b\u9884\u540e\u98ce\u9669\u6307\u6807\u540e\u662f\u5426\u4f1a\u5f71\u54cd\u80c6\u7ba1\u635f\u4f24\u98ce\u9669\u7684\u6548\u679c\u3002\u6709\u8bc1\u636e\u8868\u660e\u6025\u6027\u80c6\u56ca\u708e\u7684\u5b58\u5728\u4f1a\u589e\u52a0\u80c6\u7ba1\u635f\u4f24\u548c\u75c5\u6b7b\u7387\u7684\u98ce\u9669\u3002\u76ee\u524d\u4e5f\u5b58\u5728\u8bc4\u4f30\u6025\u6027\u80c6\u56ca\u708e\u4e25\u91cd\u7a0b\u5ea6\u7684\u5206\u7ea7\/\u98ce\u9669\u5206\u5c42\u7cfb\u7edf\u59822013\u7248\u4e1c\u4eac\u6307\u5357\uff08TG13\uff09\u30012018\u7248\u4e1c\u4eac\u6307\u5357\uff08TG18\uff09\u548c\u7f8e\u56fd\u521b\u4f24\u5916\u79d1\u534f\u4f1a\uff08AAST\uff09\u7b49\u3002\u540c\u65f6\uff0c\u4e5f\u6709\u8bc1\u636e\u8868\u660e\u968f\u7740TG13\/TG18\u5b9a\u4e49\u7684\u708e\u75c7\u4e25\u91cd\u7a0b\u5ea6\u7684\u5347\u9ad8\uff0c\u80c6\u7ba1\u635f\u4f24\u7684\u98ce\u9669\u4e5f\u589e\u52a0\u3002GDG\u8ba4\u4e3a\uff0c\u5bf9\u4e8e\u6025\u6027\u80c6\u56ca\u708e\u75c5\u4eba\uff0c\u5efa\u8bae\u5916\u79d1\u533b\u751f\u4f7f\u7528TG18\u3001AAST\u5206\u7ea7\u6807\u51c6\u6216\u5176\u4ed6\u6709\u6548\u7684\u98ce\u9669\u5206\u5c42\u6a21\u578b\u8bc4\u4f30\u80c6\u56ca\u708e\u7684\u4e25\u91cd\u7a0b\u5ea6\uff08\u4e13\u5bb6\u5171\u8bc6\uff09\u3002\u5728LC\u7684\u672f\u524d\u89c4\u5212\u548c\u672f\u4e2d\u51b3\u7b56\u4e2d\uff0c\u5efa\u8bae\u5916\u79d1\u533b\u751f\u8003\u8651\u6f5c\u5728\u589e\u52a0LC\u624b\u672f\u96be\u5ea6\u7684\u56e0\u7d20\u5982\u7537\u6027\u3001\u9ad8\u9f84\u3001\u6162\u6027\u80c6\u56ca\u708e\u3001\u80a5\u80d6\u75c7\u3001\u809d\u786c\u5316\u3001\u8179\u90e8\u624b\u672f\u53f2\u6240\u81f4\u7c98\u8fde\u3001\u6025\u8bca\u80c6\u56ca\u5207\u9664\u672f\u3001\u80c6\u56ca\u7ba1\u7ed3\u77f3\u3001\u809d\u810f\u80bf\u5927\u3001\u80c6\u9053\u80bf\u7624\u3001\u89e3\u5256\u53d8\u5f02\u3001\u80c6\u9053-\u80c3\u80a0\u9053\u7618\u548c\u5916\u79d1\u624b\u672f\u7ecf\u9a8c\u4e0d\u8db3\u7b49\uff08\u4e13\u5bb6\u5171\u8bc6\uff09\u3002<\/p>\n
\u672a\u6765\u9700\u8981\u5f00\u5c55\u66f4\u591a\u8bc4\u4f30\u8be5\u7c7b\u9884\u540e\u98ce\u9669\u6a21\u578b\u5982\u4f55\u5f71\u54cd\u4e34\u5e8a\u51b3\u7b56\u548c\u80c6\u7ba1\u635f\u4f24\u98ce\u9669\u7684\u7814\u7a76\u3002 <\/p>\n
5 \u624b\u672f\u64cd\u4f5c\u6280\u5de7<\/p>\n
5.1 \u6025\u6027\u80c6\u56ca\u708e\u75c5\u4eba\u624b\u672f\u65f6\u673a \u6025\u6027\u80c6\u56ca\u708e\u75c5\u4eba\u7684\u624b\u672f\u65f6\u673a\u4e0e\u5176\u4e25\u91cd\u7a0b\u5ea6\u6709\u5173\u3002\u4e00\u9879\u57fa\u4e8e\u4eba\u7fa4\u503e\u5411\u6027\u5339\u914d\u8bc4\u5206\u7684\u56de\u987e\u6027\u7814\u7a76\uff087110\u5bf9\u503e\u5411\u5339\u914d\u75c5\u4eba\uff09\u53d1\u73b0\uff0c\u65e9\u671f\u80c6\u56ca\u5207\u9664\u672f\u75c5\u4eba\uff08\u65e9\u671f\u624b\u672f\u88ab\u5b9a\u4e49\u4e3a\u5165\u96627 d\u4e4b\u5185\u624b\u672f\uff09\u7684\u80c6\u7ba1\u635f\u4f24\u53d1\u751f\u7387\u8f83\u5ef6\u8fdf\u624b\u672f\u75c5\u4eba\uff08\u8d85\u51fa\u65e9\u671f\u624b\u672f\u65f6\u95f4\u8de8\u5ea6\uff0c\u56db\u5206\u4f4d\u6570\u95f4\u8ddd\u4e3a4~12\u5468\uff09\u660e\u663e\u964d\u4f4e\uff08OR 0.53\uff0c95%CI 0.31\uff5e0.90\uff09\uff0c\u4e24\u7ec4\u75c5\u4eba\u75c5\u6b7b\u7387\u5206\u522b\u662f0.46%\u548c0.64%\uff0c\u65e9\u671f\u5207\u9664\u7684\u76f8\u5bf9\u98ce\u9669\u8f83\u5c0f\uff08OR 0.73\uff0cP=0.21\uff09\uff0c\u4f46\u5176\u786e\u5b9a\u6027\u8bc1\u636e\u8f83\u4f4e\uff3b11\uff3d\u3002\u540c\u65f6\uff0c\u7814\u7a76\u8868\u660e\u8f7b\u5ea6\u6025\u6027\u80c6\u56ca\u708e\u75c5\u4eba\u624b\u672f\u5e76\u6ca1\u6709\u589e\u52a0\u80c6\u7ba1\u635f\u4f24\u7684\u53d1\u751f\u7387\uff0c\u800c\u4e2d\u5ea6\u548c\u91cd\u5ea6\u6025\u6027\u80c6\u56ca\u708e\u4f7f\u80c6\u7ba1\u635f\u4f24\u75c5\u4eba\u7684\u53d1\u751f\u7387\u660e\u663e\u589e\u52a0\uff3b12\uff3d\u3002GDG\u8ba4\u4e3a\uff0c\u5bf9\u4e8e\u8f7b\u5ea6\u6025\u6027\u80c6\u56ca\u708e\u75c5\u4eba\uff08\u4f9d\u636e\u4e1c\u4eac\u6307\u5357\uff09\uff0c\u5efa\u8bae\u5916\u79d1\u533b\u751f\u5728\u75c7\u72b6\u53d1\u4f5c\u768472 h\u5185\u65bd\u884cLC\u624b\u672f\uff08\u6761\u4ef6\u6027\u63a8\u8350\uff0c\u786e\u5b9a\u6027\u8bc1\u636e\u975e\u5e38\u4f4e\uff09\u3002\u5bf9\u4e8e\u4e2d\u3001\u91cd\u5ea6\u80c6\u56ca\u708e\u75c5\u4eba\uff0c\u5e76\u6ca1\u6709\u5145\u8db3\u7684\u8bc1\u636e\u652f\u6301\u76f8\u5e94\u7684\u63a8\u8350\u610f\u89c1\u3002<\/p>\n
\u672a\u6765\u62df\u63a2\u7a76\u80c6\u7ba1\u635f\u4f24\u548c\u6025\u6027\u80c6\u56ca\u708e\u4e25\u91cd\u7a0b\u5ea6\u76f8\u5173\u6027\u7684\u7814\u7a76\uff0c\u5e94\u505a\u597d\u6025\u6027\u80c6\u56ca\u708e\u4e25\u91cd\u7a0b\u5ea6\u548c\u53d1\u4f5c\u53f2\u7b49\u75c5\u4eba\u57fa\u7ebf\u8d44\u6599\u7684\u914d\u5bf9\u3002\u6025\u6027\u80c6\u56ca\u708e\u7684\u8bca\u65ad\u65b9\u6cd5\u5e94\u8be5\u4f9d\u636e\u5e38\u7528\u7684\u4e34\u5e8a\u6807\u51c6\u5982TG18\u8bca\u65ad\u6807\u51c6\u6216\u6025\u6027\u708e\u75c7\u7684\u7ec4\u7ec7\u5b66\u8868\u73b0\u3002\u5efa\u8bae\u5c06\u6025\u6027\u80c6\u56ca\u708e\u624b\u672f\u4e0e\u75c7\u72b6\u53d1\u4f5c\u95f4\u9694\u5206\u4e3a4\u4e2a\u65f6\u76f8\uff0c\u2160\u671f\uff1a\u75c7\u72b6\u53d1\u4f5c\u540e72 h\u4e4b\u5185\uff1b\u2161\u671f\uff1a\u75c7\u72b6\u53d1\u4f5c\u540e72 h\u81f310 d\u5185\uff1b\u2162\u671f\uff1a\u75c7\u72b6\u53d1\u4f5c\u540e10 d\u81f36\u5468\uff1b\u2163\u671f\uff1a\u75c7\u72b6\u53d1\u4f5c\u540e\u76846\u5468\u6216\u4ee5\u4e0a\u3002<\/p>\n
5.2 LC\u4e2d\u5b58\u5728\u708e\u75c7\u65f6\u624b\u672f\u7b56\u7565 \u56e0\u6ca1\u6709\u76f4\u63a5\u6216\u95f4\u63a5\u7684\u8bc1\u636e\uff0cGDG\u8ba4\u4e3a\u5f53\u672f\u4e2d\u6761\u4ef6\u5dee\uff0c\u65e0\u6cd5\u83b7\u5f97\u6e05\u6670\u7684\u89e3\u5256\u65f6\uff0c\u5e94\u7528STC\u53ef\u80fd\u901a\u8fc7\u907f\u514d\u89e3\u5256\u80c6\u56ca\u4e09\u89d2\u800c\u964d\u4f4e\u80c6\u7ba1\u635f\u4f24\u98ce\u9669\u3002\u5f53LC\u4e2d\u660e\u663e\u7684\u6025\u6027\u5c40\u90e8\u708e\u75c7\u6216\u6162\u6027\u5f25\u6f2b\u6027\u708e\u75c7\u963b\u788d\u4e86\u80c6\u56ca\u7ba1\u548c\u52a8\u8109\u7684\u89e3\u5256\u65f6\uff0c\u5efa\u8bae\u5916\u79d1\u533b\u751f\u4f9d\u636e\u5176\u4e34\u5e8a\u7ecf\u9a8c\u548c\u64cd\u4f5c\u719f\u6089\u5ea6\u6765\u65bd\u884c\u8179\u8154\u955c\u4e0b\u6216\u5f00\u8179STC\uff08\u4e13\u5bb6\u5171\u8bc6\uff09\u3002\u672a\u6765\u8fd8\u9700\u524d\u77bb\u6027\u968f\u673a\u5bf9\u7167\u4e34\u5e8a\u8bd5\u9a8c\u7ed3\u679c\u8fdb\u4e00\u6b65\u8bc1\u5b9e\u3002<\/p>\n
5.3 \u80c6\u56ca\u5207\u9664\u624b\u672f\u65b9\u6cd5\u7684\u9009\u53d6 \u76ee\u524d\u4e0d\u5b58\u5728\u76f4\u63a5\u7684\u5bf9\u6bd4\u6027\u8bc1\u636e\u8868\u660e\u6807\u51c6\u56db\u5b54LC\u3001\u5355\u5b54LC\u3001\u673a\u5668\u4eba\u80c6\u56ca\u5207\u9664\u672f\u3001\u5f00\u653e\u80c6\u56ca\u5207\u9664\u672f\u6216\u5176\u4ed6\u624b\u672f\u65b9\u6cd5\u5728\u964d\u4f4e\u80c6\u56ca\u5207\u9664\u75c5\u4eba\u80c6\u7ba1\u635f\u4f24\u7684\u98ce\u9669\u6216\u4e25\u91cd\u7a0b\u5ea6\u4e0a\u7684\u4f18\u52a3\u3002\u5c3d\u7ba1\u5173\u4e8e\u4e0d\u540c\u624b\u672f\u65b9\u6cd5\u9884\u540e\u7684\u786e\u5b9a\u6027\u8bc1\u636e\u7ea7\u522b\u6709\u6240\u4e0d\u540c\uff0c\u4f46\u662f\u8bc1\u636e\u59cb\u7ec8\u652f\u6301\u6807\u51c6\u56db\u5b54LC\u80fd\u591f\u5e26\u6765\u66f4\u597d\u7684\u9884\u540e\uff08\u80c6\u7ba1\u635f\u4f24\u7387\u548c\u4e25\u91cd\u5e76\u53d1\u75c7\u7387\uff09\uff3b13\uff3d\u3002\u5bf9\u4e8e\u624b\u672f\u7ecf\u9a8c\u4e30\u5bcc\u7684\u533b\u751f\uff0c\u5355\u5b54LC\u4e5f\u53ef\u80fd\u83b7\u5f97\u7c7b\u4f3c\u7684\u6548\u679c\u3002\u56e0\u800c\uff0cGDG\u8ba4\u4e3a\u82e5\u62df\u884c\u80c6\u56ca\u5207\u9664\u672f\uff0c\u5efa\u8bae\u65bd\u884c\u591a\u5b54\u8179\u8154\u955c\u624b\u672f\u800c\u975e\u5355\u5b54\u8179\u8154\u955c\u624b\u672f\uff08\u6761\u4ef6\u6027\u63a8\u8350\uff0c\u786e\u5b9a\u6027\u8bc1\u636e\u4e2d\u7b49\uff09\u3002<\/p>\n
5.4 \u66fe\u884c\u80c6\u56ca\u9020\u53e3\u672f\u75c5\u4eba\u624b\u672f\u7b56\u7565 GDG\u8ba4\u4e3a\uff0c\u5bf9\u4e8e\u66fe\u884c\u80c6\u56ca\u9020\u53e3\u672f\u7684\u6025\u6027\u7ed3\u77f3\u6027\u80c6\u56ca\u708e\u4e14\u9002\u5b9c\u624b\u672f\u7684\u75c5\u4eba\uff0c\u5efa\u8bae\u5f85\u708e\u75c7\u6d88\u9000\u540e\u884c\u5ef6\u8fdf\u6027\u80c6\u56ca\u5207\u9664\u672f\u3002\u5bf9\u4e8e\u4e0d\u9002\u5b9c\u884c\u624b\u672f\u6cbb\u7597\u6216\u624b\u672f\u6761\u4ef6\u5dee\u7684\u75c5\u4eba\uff0c\u5efa\u8bae\u65bd\u884c\u975e\u624b\u672f\u6cbb\u7597\u65b9\u6cd5\u5982\u901a\u8fc7\u80c6\u56ca\u7a7f\u523a\u5f15\u6d41\u7ba1\u6e05\u9664\u80c6\u56ca\u7ed3\u77f3\u6216\u82e5\u9020\u5f71\u663e\u793a\u80c6\u56ca\u7ba1\u901a\u7545\uff0c\u53ef\u62d4\u9664\u5f15\u6d41\u7ba1\u548c\u89c2\u5bdf\uff08\u4e13\u5bb6\u5171\u8bc6\uff09\u3002\u76ee\u524d\u5e76\u6ca1\u6709\u76f4\u63a5\u7684\u5bf9\u6bd4\u6027\u8bc1\u636e\u56de\u7b54\u8fd9\u4e2a\u95ee\u9898\uff0c\u73b0\u6709\u7684\u56de\u987e\u6027\u7814\u7a76\u90fd\u5b58\u5728\u4e00\u5b9a\u7a0b\u5ea6\u7684\u9009\u62e9\u504f\u501a\uff0c\u56e0\u800c\u8be5\u63a8\u8350\u610f\u89c1\u7684\u8bc1\u636e\u7ea7\u522b\u90fd\u8f83\u4f4e\u3002\u672a\u6765\u8fd8\u9700\u5f00\u5c55\u524d\u77bb\u6027\u968f\u673a\u5bf9\u7167\u4e34\u5e8a\u8bd5\u9a8c\u8fdb\u4e00\u6b65\u63a2\u7a76\u3002<\/p>\n
5.5 \u56f0\u96beLC\u7684\u624b\u672f\u7b56\u7565 \u5728\u56f0\u96beLC\u4e2d\uff0c\u662f\u5426\u5e94\u8be5\u4e2d\u8f6c\u5f00\u8179\u4ee5\u964d\u4f4e\u672f\u4e2d\u80c6\u7ba1\u635f\u4f24\u7684\u98ce\u9669\u6216\u7a0b\u5ea6\uff0c\u56e0\u8bc1\u636e\u4e0d\u8db3\uff0c\u5c1a\u672a\u660e\u786e\u3002\u56f0\u96beLC\u7684\u672f\u4e2d\u80c6\u7ba1\u635f\u4f24\u53d1\u751f\u7387\u8f83\u9ad8\uff0c\u7136\u800c\u66f4\u591a\u7684\u80c6\u7ba1\u635f\u4f24\uff0c\u53d1\u751f\u5728\u6240\u8c13\u201c\u7b80\u5355\u201dLC\u4e2d\uff0c\u53ef\u80fd\u4e0e\u672f\u8005\u672f\u4e2d\u91cd\u89c6\u5ea6\u4e0d\u540c\u6709\u5173\u3002<\/p>\n
GDG\u5efa\u8bae\u672a\u6765\u5f00\u5c55\u5bf9\u6bd4\u56f0\u96beLC\u7684\u672f\u4e2d\u4e0d\u540c\u5904\u7406\u7b56\u7565\u548c\u5bf9\u5e94\u9884\u540e\u7684\u524d\u77bb\u6027\u6216\u56de\u987e\u6027\u7814\u7a76\uff1b\u540c\u65f6\uff0c\u5efa\u8bae\u5efa\u7acbLC\u201c\u64cd\u4f5c\u96be\u5ea6\u8bc4\u5206\u201d\uff0c\u5e76\u63a2\u7a76\u5176\u5728\u80c6\u7ba1\u635f\u4f24\u98ce\u9669\u4e2d\u7684\u4f5c\u7528\u3002<\/p>\n
5.6 \u672f\u4e2d\u80c6\u7ba1\u635f\u4f24\u5904\u7406\u7b56\u7565 \u76ee\u524d\u5e76\u6ca1\u6709RCT\u7814\u7a76\u548c\u7cfb\u7edf\u8bc4\u4ef7\u660e\u786eLC\u4e2d\u80c6\u7ba1\u635f\u4f24\u540e\u7531\u539f\u624b\u672f\u533b\u751f\u8fd8\u662f\u8f6c\u8bca\u81f3\u80c6\u9053\u4fee\u590d\u7ecf\u9a8c\u4e30\u5bcc\u7684\u4e2d\u5fc3\u8fdb\u884c\u80c6\u9053\u91cd\u5efa\u7684\u4e34\u5e8a\u6548\u679c\u7684\u4f18\u52a3\u30027\u9879\u89c2\u5bdf\u6027\u7814\u7a76\uff08\u7eb3\u51651392\u4f8b\u80c6\u7ba1\u635f\u4f24\u75c5\u4eba\uff09\u6c47\u603b\u5206\u6790\u8868\u660e\uff0c\u76f8\u5bf9\u4e8e\u539f\u624b\u672f\u533b\u751f\uff0c\u4e13\u79d1\u533b\u751f\u5904\u7406\u53ef\u4f7f\u75c5\u4eba\u83b7\u5f97\u66f4\u597d\u7684\u9884\u540e\u3002GDG\u8ba4\u4e3a\uff0c\u80c6\u56ca\u5207\u9664\u672f\u4e2d\u6216\u672f\u540e\u53d1\u73b0\u6216\u9ad8\u5ea6\u6000\u7591\u80c6\u7ba1\u635f\u4f24\u65f6\uff0c\u5efa\u8bae\u5916\u79d1\u533b\u751f\u7acb\u5373\u63a8\u8350\u8be5\u75c5\u4eba\u8f6c\u8bca\u5230\u5177\u6709\u80c6\u7ba1\u635f\u4f24\u5904\u7406\u7ecf\u9a8c\u7684\u5916\u79d1\u533b\u751f\u6765\u6cbb\u7597\u3002\u82e5\u4e0a\u8ff0\u65b9\u5f0f\u4e0d\u80fd\u53ca\u65f6\u5b9e\u73b0\uff0c\u5e94\u8fc5\u901f\u4e0e\u635f\u4f24\u5904\u7406\u7ecf\u9a8c\u4e30\u5bcc\u7684\u5916\u79d1\u533b\u751f\u6c9f\u901a\uff08\u5f3a\u70c8\u63a8\u8350\uff0c\u786e\u5b9a\u6027\u8bc1\u636e\u4f4e\uff09\u3002<\/p>\n
Wang\u7b49\uff3b14\uff3d\u901a\u8fc7\u7eb3\u516532\u9879\u7814\u7a76\u7684Meta\u5206\u6790\u53d1\u73b0\uff0c\u672f\u4e2d\u80c6\u7ba1\u635f\u4f24\u75c5\u4eba\u7684\u65e9\u671f\u8f6c\u8bca\uff08\u22642\u5468\uff09\u76f8\u5bf9\u4e8e\u5ef6\u8fdf\u8f6c\u8bca\uff08>6\u5468\uff09\u4f1a\u5e26\u6765\u66f4\u4f4e\u7684\u80c6\u7ba1\u635f\u4f24\u4fee\u590d\u5931\u8d25\u7387\uff08OR 0.28\uff0c95% CI 0.17~0.45\uff0cP\uff1c0.01\uff09\uff0c\u800c\u65e9\u671f\u4fee\u590d\uff08\u22642\u5468\uff09\u76f8\u5bf9\u4e8e\u5ef6\u8fdf\u4fee\u590d\uff08>6\u5468\uff09\u4f1a\u5e26\u6765\u66f4\u9ad8\u7684\u80c6\u7ba1\u635f\u4f24\u4fee\u6539\u5931\u8d25\u7387\uff08OR 1.65\uff0c95% CI 1.14~2.37\uff0cP=0.007\uff09\u3002<\/p>\n
\u672a\u6765\u5e94\u5f00\u8f9f\u533a\u57df\u6027\u7684\u80c6\u7ba1\u635f\u4f24\u5feb\u901f\u8f6c\u8bca\u901a\u9053\uff0c\u4e3aLC\u4e2d\u80c6\u7ba1\u635f\u4f24\u7684\u5904\u7406\u63d0\u4f9b\u5efa\u8bae\u548c\u53ca\u65f6\u5904\u7406\u7684\u65b9\u6cd5\u3002\u540c\u65f6\uff0c\u5efa\u8bae\u5236\u5b9a\u5168\u56fd\u6027\u7684\u8d28\u91cf\u63d0\u5347\u57f9\u517b\u8ba1\u5212\u4ee5\u964d\u4f4e\u80c6\u56ca\u5207\u9664\u672f\u4e2d\u80c6\u7ba1\u635f\u4f24\u53d1\u751f\u7387\u548c\u63d0\u5347\u80c6\u7ba1\u635f\u4f24\u5904\u7406\u7684\u6c34\u5e73\u3002<\/p>\n
6 \u533b\u751f\u57f9\u8bad\u65b9\u6cd5\u548c\u7ecf\u9a8c<\/p>\n
6.1 \u9488\u5bf9\u5916\u79d1\u533b\u751f\u7684CVS\u57f9\u8bad GDG\u8ba4\u4e3a\u83b7\u5f97\u9ad8\u8d28\u91cf\u7684CVS\u5bf9\u4e8e\u907f\u514dLC\u4e2d\u80c6\u7ba1\u635f\u4f24\u81f3\u5173\u91cd\u8981\u3002\u76ee\u524d\u7684\u8bc1\u636e\u663e\u793a\uff0c\u7edd\u5927\u591a\u6570\u5916\u79d1\u533b\u751f\u5728\u5e38\u89c4LC\u624b\u672f\u4e2d\u4e0d\u80fd\u83b7\u5f97CVS\uff3b15\uff3d\u3002\u5728\u4e00\u9879\u7814\u7a76\u4e2d\uff0c5\u540d\u5916\u79d1\u533b\u751f\u5728\u63a5\u53d7CVS\u6280\u672f\u57f9\u8bad\u540e\uff0c\u5176LC\u4e2d\u8fbe\u5230CVS\u76f8\u5173\u7684Strasberg\u8bc4\u5206\u4ece1.75\u663e\u8457\u63d0\u5347\u81f33.75\uff08\u786e\u5b9a\u6027\u8bc1\u636e\u975e\u5e38\u4f4e\uff09\uff3b15\uff3d\u3002\u540c\u65f6\uff0c\u5305\u62ec\u5916\u79d1\u5728\u5185\u7684\u8bb8\u591a\u9886\u57df\u7684\u8bc1\u636e\u4e5f\u652f\u6301\u76f8\u5173\u57f9\u8bad\u80fd\u5e26\u6765\u66f4\u597d\u7684\u624b\u672f\u6548\u679c\uff3b16-17\uff3d\u3002\u56e0\u800c\u57fa\u4e8e\u4ee5\u4e0a\u8bc1\u636e\uff0cGDG\u5efa\u8bae\u5bf9\u5916\u79d1\u533b\u751f\u8fdb\u884cLC\u4e2d\u7684CVS\u57f9\u8bad\uff08\u6761\u4ef6\u6027\u63a8\u8350\uff0c\u786e\u5b9a\u6027\u8bc1\u636e\u975e\u5e38\u4f4e\uff09\u3002<\/p>\n
6.2 \u4eff\u771f\u3001\u89c6\u9891\u6559\u5b66\u6216\u5176\u4ed6\u5916\u79d1\u57f9\u8bad\u65b9\u6cd5 \u76ee\u524d\u76f8\u5173\u8bc1\u636e\u4e0d\u8db3\u4ee5\u660e\u786e\u4eff\u771f\u3001\u89c6\u9891\u6559\u5b66\u6216\u5176\u4ed6\u5916\u79d1\u57f9\u8bad\u65b9\u6cd5\u662f\u5426\u80fd\u591f\u964d\u4f4eLC\u4e2d\u80c6\u7ba1\u635f\u4f24\u7684\u98ce\u9669\u6216\u7a0b\u5ea6\u3002GDG\u5efa\u8bae\u5f00\u5c55\u5927\u578b\u591a\u4e2d\u5fc3\u3001\u524d\u77bb\u6027\u7814\u7a76\u4ee5\u660e\u786e\u4eff\u771f\u624b\u672f\u3001\u89c6\u9891\u6559\u5b66\u6216\u5176\u4ed6\u5916\u79d1\u57f9\u8bad\u6a21\u5f0f\u5728\u964d\u4f4e\u80c6\u7ba1\u635f\u4f24\u53d1\u751f\u7387\u4e2d\u7684\u4f5c\u7528\u3002\u5e94\u8be5\u53d1\u5c55\u66f4\u591a\u878d\u5408\u6c89\u6d78\u5f0f\u865a\u62df\u6280\u672f\u548c\u9ad8\u7ea7\u4eff\u771f\u89e6\u89c9\u7684\u6a21\u62df\u8bbe\u5907\uff0c\u5176\u6548\u7528\u4e5f\u987b\u8fdb\u4e00\u6b65\u660e\u786e\u3002<\/p>\n
6.3 \u5916\u79d1\u624b\u672f\u7ecf\u9a8c \u7406\u8bba\u4e0a\uff0c\u66f4\u4e30\u5bcc\u7684\u5916\u79d1\u624b\u672f\u7ecf\u9a8c\u4f1a\u5e26\u6765\u66f4\u597d\u7684\u4e34\u5e8a\u8bca\u7597\u6548\u679c\u3002\u4e00\u9879\u57fa\u4e8e\u7f8e\u56fd\u8179\u8154\u955c\u5916\u79d1\u533b\u5e08\u6570\u636e\u5e93\u7684\u89c2\u5bdf\u6027\u7814\u7a76\uff0823\u9879\u7814\u7a76\uff0cn=53 632\uff09\u53d1\u73b0\uff0c\u7ecf\u9a8c\u66f4\u4e30\u5bcc\u7684\u5916\u79d1\u533b\u751f\uff08\u5b9e\u8df5\u5e73\u574720.7\u5e74vs. 6.1\u5e74\uff09\u7ecf\u5386\u7684\u80c6\u7ba1\u635f\u4f24\u53d1\u751f\u7387\u66f4\u4f4e\uff080.14% vs.0.47%\uff0cP=0.0013\uff0cRR 0.27\uff0c95% CI 0.13~0.57\uff09\u3002\u4f46GDG\u8003\u8651\u5230\u5176\u63a5\u53d7\u5ea6\u548c\u53ef\u884c\u6027\uff0c\u5c24\u5176\u662f\u5728\u793e\u533a\u6216\u519c\u6751\u5730\u533a\u533b\u9662\uff0c\u5e76\u6ca1\u6709\u5f3a\u70c8\u63a8\u8350\u7ecf\u9a8c\u4e30\u5bcc\u7684\u5916\u79d1\u533b\u751f\u53d6\u4ee3\u7ecf\u9a8c\u76f8\u5bf9\u8f83\u5c11\u7684\u5916\u79d1\u533b\u751f\u65bd\u884c\u624b\u672f\uff0c\u800c\u662f\u5efa\u8bae\u5916\u79d1\u533b\u751f\u5728\u9047\u5230\u624b\u672f\u56f0\u96be\u6216\u65e0\u6cd5\u83b7\u5f97\u6e05\u6670\u89e3\u5256\u7684\u60c5\u51b5\u4e0b\uff0c\u5411\u624b\u672f\u7ecf\u9a8c\u4e30\u5bcc\u7684\u533b\u751f\u6c42\u52a9\uff08\u6761\u4ef6\u6027\u63a8\u8350\uff0c\u786e\u5b9a\u6027\u8bc1\u636e\u975e\u5e38\u4f4e\uff09\u3002\u8be5\u63a8\u8350\u610f\u89c1\u4e5f\u8f83\u4e3a\u9002\u5408\u56fd\u5185\u533b\u7597\u73b0\u72b6\u3002\u5efa\u8bae\u8fdb\u4e00\u6b65\u5f00\u5c55\u524d\u77bb\u6027\u7814\u7a76\u4ee5\u660e\u786e\u5916\u79d1\u533b\u751f\u624b\u672f\u7ecf\u9a8c\u5728\u964d\u4f4eLC\u4e2d\u80c6\u7ba1\u635f\u4f24\u53d1\u751f\u7387\u7684\u4f5c\u7528\u3002<\/p>\n
\u8be5\u6307\u5357\u4ece\u80c6\u56ca\u5207\u9664\u672f\u4e2d\u7684\u64cd\u4f5c\u6280\u5de7\u3001\u5f71\u50cf\u5b66\u624b\u6bb5\u3001\u98ce\u9669\u8bc4\u4f30\u3001\u624b\u672f\u65f6\u673a\u3001\u624b\u672f\u5668\u68b0\u7684\u5e94\u7528\u3001\u533b\u751f\u7684\u7ecf\u9a8c\u4e0e\u914d\u5408\u3001\u533b\u751f\u57f9\u8bad\u65b9\u6cd5\u548c\u80c6\u7ba1\u635f\u4f24\u8f6c\u8bca\u901a\u9053\u7b49\u591a\u65b9\u9762\u8fdb\u884c\u4e86\u63a2\u8ba8\u548c\u603b\u7ed3\uff1b\u5168\u65b9\u9762\u548c\u591a\u89d2\u5ea6\u56de\u7b54\u4e86\u80c6\u56ca\u5207\u9664\u672f\u4e2d\u80c6\u7ba1\u635f\u4f24\u7684\u9884\u9632\u548c\u5904\u7406\u7684\u70ed\u70b9\u95ee\u9898\uff0c\u4e3a\u4e34\u5e8a\u533b\u751f\u5c24\u5176\u662f\u5e74\u8f7b\u5916\u79d1\u533b\u751f\u63d0\u4f9b\u4e86\u8f83\u4e3a\u5145\u8db3\u7684\u7ecf\u9a8c\u6307\u5bfc\uff0c\u4e5f\u4e3a\u672a\u6765\u5f00\u5c55\u80c6\u7ba1\u635f\u4f24\u7684\u76f8\u5173\u4e34\u5e8a\u7814\u7a76\u65b9\u5411\u63d0\u4f9b\u4e86\u65b0\u7684\u601d\u8def\u548c\u542f\u53d1\uff0c\u8be5\u6307\u5357\u503c\u5f97\u5728\u6211\u56fd\u5916\u79d1\u754c\u5206\u4eab\u548c\u63a8\u5e7f\uff3b18-21\uff3d\u3002\u4f46\u662f\u8be5\u6307\u5357\u7684\u63a8\u8350\u610f\u89c1\u4e3b\u8981\u9002\u7528\u4e8e\u7406\u60f3\u7684\u533b\u7597\u6761\u4ef6\u548c\u8bbe\u5907\u60c5\u51b5\u4e0b\uff0c\u6211\u56fd\u4e0d\u540c\u7ea7\u522b\u7684\u8bca\u7597\u673a\u6784\u5c24\u5176\u662f\u57fa\u5c42\u533b\u9662\u9700\u8981\u7ed3\u5408\u533b\u9662\u8d44\u6e90\u548c\u75c5\u4eba\u7ecf\u6d4e\u72b6\u51b5\u7684\u5b9e\u9645\u60c5\u51b5\u8fdb\u884c\u63a8\u5e7f\u5e94\u7528\u3002\u7b14\u8005\u76f8\u4fe1\uff0c\u968f\u7740\u6211\u56fd\u5728\u809d\u80c6\u80f0\u5916\u79d1\u75be\u75c5\u8bca\u6cbb\u7684\u7ecf\u9a8c\u79ef\u7d2f\u548c\u7814\u7a76\u6295\u5165\uff0c\u5728\u4e0d\u4e45\u7684\u5c06\u6765\uff0c\u6211\u56fd\u7684\u4e34\u5e8a\u7ecf\u9a8c\u4e5f\u4f1a\u4e3a\u76f8\u5173\u7684\u4e13\u5bb6\u5171\u8bc6\u548c\u6307\u5357\u8d21\u732e\u66f4\u591a\u3001\u66f4\u4e30\u5bcc\u548c\u66f4\u6709\u529b\u7684\u5faa\u8bc1\u533b\u5b66\u8bc1\u636e\u3002<\/p>\n
\u9644\u5f55\uff1a\u4e13\u6709\u540d\u8bcd\u89e3\u91ca<\/p>\n
\u5173\u952e\u5b89\u5168\u89c6\u91ce\uff08critical view of safety\uff0cCVS\uff09\uff1aStrasberg\u7b49\u57281995\u5e74\u63d0\u51fa\u7684LC\u624b\u672f\u7684\u9ec4\u91d1\u51c6\u5219\uff0c\u662f\u6307\u89e3\u5256\u80c6\u56ca\u4e09\u89d2\u5185\u7ec4\u7ec7\uff0c\u4ea4\u66ff\u5411\u4e0b\u5916\u4fa7\u548c\u4e0a\u5185\u4fa7\u7275\u62c9\u80c6\u56ca\u9888\u4ee5\u9010\u6b65\u5206\u79bb\u80c6\u56ca\u4e0e\u809d\u810f\uff0c\u8fd9\u6837\u5c31\u5f62\u6210\u4e86\u4e00\u4e2a\u7531\u80c6\u56ca\u548c\u809d\u5341\u4e8c\u6307\u80a0\u97e7\u5e26\u4e4b\u95f4\u76f8\u8fde\u7684\u7ed3\u6784\uff0c\u5176\u5185\u53ea\u6709\u80c6\u56ca\u7ba1\u548c\u80c6\u56ca\u52a8\u8109\u901a\u8fc7\uff0c\u8fd9\u662f\u5939\u95ed\u548c\u79bb\u65ad\u4efb\u4f55\u7ba1\u72b6\u7ed3\u6784\u524d\u5e94\u8be5\u8fbe\u5230\u7684\u89c6\u91ce\uff08\u9644\u56fe1a\uff09\u3002<\/p>\n
\u58f6\u8179\u90e8\u6280\u672f\uff08infundibular technique\uff09\uff1aStrasberg\u7b49\u4e5f\u63d0\u51fa\u4f9d\u636e\u80c6\u56ca\u7ba1\u548c\u80c6\u56ca\u8fde\u63a5\u90e8\u8fdb\u884c\u89e3\u5256\u8fa8\u8bc6\u65b9\u6cd5\uff0c\u4f46\u5728\u90e8\u5206\u75c5\u4f8b\u4e2d\u53ef\u80fd\u4f1a\u56e0\u708e\u75c7\u5305\u5757\u5305\u88f9\u80c6\u56ca\u7ba1\u800c\u8bef\u5c06\u80c6\u603b\u7ba1\u5f53\u4f5c\u80c6\u56ca\u7ba1\uff08\u9644\u56fe1b\uff09\u3002<\/p>\n<\/p>\n
\u8fd1\u7ea2\u5916\uff08NIR\uff09\u80c6\u9053\u663e\u5f71\uff1a\u5168\u79f0\u4e3a\u8fd1\u7ea2\u5916\u8367\u5149\u80c6\u9053\u663e\u5f71\u6280\u672f\uff0c\u662f\u4e00\u79cd\u80fd\u591f\u5b9e\u65f6\u89c2\u5bdf\u809d\u5916\u80c6\u7ba1\u7cfb\u7edf\u7684\u65b0\u578b\u663e\u50cf\u6a21\u5f0f\uff0c\u672f\u524d\u9759\u8109\u6ce8\u5c04\u7684\u5432\u54da\u83c1\u7eff\u6392\u6cc4\u81f3\u80c6\u9053\u7cfb\u7edf\u53ef\u5728\u8fd1\u7ea2\u5916\u6fc0\u5149\u7684\u6fc0\u53d1\u4e0b\u5728\u663e\u793a\u5668\u4e2d\u5b9e\u73b0\u663e\u73b0\u80c6\u9053\u7cfb\u7edf\u7684\u8f6e\u5ed3\u7ed3\u6784\u3002<\/p>\n
\u767d\u5149\u5f71\u50cf\uff1a\u7535\u5b50\u5185\u955c\u4e0b\u7684\u767d\u5149LED\u7167\u5c04\u4e0b\u7684\u89c6\u91ce\u5f71\u50cf\uff0c\u662f\u5e38\u89c4\u8179\u8154\u955c\u624b\u672f\u6700\u5e38\u7528\u7684\u5149\u6e90\u5f71\u50cf\u3002<\/p>\n
\u5373\u65f6\u80c6\u56ca\u5207\u9664\u672f\uff0c\u5ef6\u8fdf\u80c6\u56ca\u5207\u9664\u672f\uff1a\u5373\u65f6\u80c6\u56ca\u5207\u9664\u672f\u88ab\u5b9a\u4e49\u4e3a\u75c7\u72b6\u53d1\u4f5c\u768472 h\u5185\u65bd\u884c\u624b\u672f\uff0c\u5ef6\u8fdf\u80c6\u56ca\u5207\u9664\u672f\u88ab\u5b9a\u4e49\u4e3a\u75c7\u72b6\u53d1\u4f5c\u540e\u768472 h\u81f310 d\u4e4b\u95f4\u624b\u672f\u6216\u75c7\u72b6\u53d1\u4f5c\u76846~12\u5468\u624b\u672f\u6216\u75c7\u72b6\u53d1\u4f5c\u768412\u5468\u4ee5\u4e0a\u624b\u672f\u3002<\/p>\n
\u80c6\u56ca\u5e95\u4f18\u5148\u663e\u9732\u6280\u672f\uff08\u201cfundus-first\u201d\/top down technique\uff09\uff1a\u53c8\u79f0\u9006\u884c\u80c6\u56ca\u5207\u9664\u672f\uff0c\u9996\u5148\u4ece\u80c6\u56ca\u5e95\u90e8\u5165\u624b\uff0c\u81ea\u80c6\u56ca\u5e95\u5207\u5f00\u80c6\u56ca\u6d46\u808c\u5c42\u627e\u5230\u5206\u79bb\u5e73\u9762\uff0c\u949d\u6027\u5206\u79bb\u80c6\u56ca\u548c\u80c6\u56ca\u7a9d\u809d\u5e8a\u4e4b\u95f4\u7684\u7ec4\u7ec7\uff0c\u5fc5\u8981\u65f6\u53ef\u6b8b\u7559\u90e8\u5206\u80c6\u56ca\u7ec4\u7ec7\uff08\u9644\u56fe2\uff09\u3002<\/p>\n<\/p>\n
\u80c6\u56ca\u5927\u90e8\u5207\u9664\u672f\uff08subtotal cholecystectomy\uff0cSTC\uff09\uff1a\u6307\u5c06\u80c6\u56ca\u5e95\u90e8\u3001\u4f53\u90e8\u548c\u9888\u90e8\u4e4b\u524d\u7684\u524d\u58c1\u548c\u540e\u58c1\u5927\u90e8\u5206\u5207\u9664\uff0c\u5c06\u80c6\u56ca\u5185\u7ed3\u77f3\u7b49\u53d6\u51c0\uff0c\u7559\u4e0b\u7c98\u8fde\u81f4\u5bc6\u7684\u90e8\u5206\u540e\u58c1\u5e76\u5c06\u6b8b\u7559\u7684\u540e\u58c1\u9ecf\u819c\u7834\u574f\uff0c\u5206\u79bb\u7ed3\u624e\u80c6\u56ca\u7ba1\u5e76\u7f1d\u624e\u6b8b\u7aef\u7684\u624b\u672f\u65b9\u6cd5\uff08\u9644\u56fe3\uff09\u3002<\/p>\n<\/p>\n
\u53c2\u8003\u6587\u732e<\/p>\n
\uff08\u5728\u6846\u5185\u6ed1\u52a8\u624b\u6307\u5373\u53ef\u6d4f\u89c8\uff09<\/p>\n
\uff3b1\uff3d Brunt LM\uff0cDeziel DJ\uff0cTelem DA\uff0cet al. Safe cholecystectomy multi-society practice guideline and state of the art consensus conference on prevention of bile duct injury during cholecystectomy\uff3bJ\uff3d.Ann Surg,2020, 272(1):1.<\/p>\n
\uff3b2\uff3d Avgerinos C\uff0cKelgiorgi D\uff0cTouloumis Z\uff0cet al.One thousand laparoscopic cholecystectomies in a single surgical unit using the ‘critical view of safety’ technique\uff3bJ\uff3d.J Gastrointest Surg\uff0c2009\uff0c13\uff083\uff09\uff1a498-503.<\/p>\n
\uff3b3\uff3d Sanjay P\uff0cFulke JL\uff0cExon DJ.’Critical view of safety’ as an alternative to routine intraoperative cholangiography during laparoscopic cholecystectomy for acute biliary pathology\uff3bJ\uff3d.J Gastrointest Surg\uff0c2010\uff0c14\uff088\uff09\uff1a1280-1284.<\/p>\n
\uff3b4\uff3d Tsalis K\uff0cAntoniou N\uff0cKoukouritaki Z\uff0cet al.Open-access technique and ‘critical view of safety’ as the safest way to perform laparoscopic cholecystectomy\uff3bJ\uff3d. Surg Laparosc Endosc Percutan Tech\uff0c2014\uff0c25\uff082\uff09\uff1a119-124.<\/p>\n
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\uff3b21\uff3d \u95eb\u52a0\u8273\uff0c\u674e\u592a\u9521\uff0c\u4f55\u654f\uff0c\u7b49.\u4e09\u7ef4\u53ef\u89c6\u5316\u6280\u672f\u5728\u533b\u6e90\u6027\u80c6\u7ba1\u635f\u4f24\u540e\u72ed\u7a84\u672f\u524d\u8bc4\u4f30\u4e2d\u5e94\u7528\u7814\u7a76\uff3bJ\uff3d.\u4e2d\u56fd\u5b9e\u7528\u5916\u79d1\u6742\u5fd7\uff0c2018\uff0c38\uff089\uff09\uff1a1031-1038.<\/p>\n
\uff082020-09-19\u6536\u7a3f 2020-10-03\u4fee\u56de\uff09<\/p>\n","protected":false},"excerpt":{"rendered":"
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