{"id":37110,"date":"2024-06-15T04:02:08","date_gmt":"2024-06-15T04:02:08","guid":{"rendered":"https:\/\/zydq.1006ss.com\/?p=37110"},"modified":"2024-06-15T04:02:08","modified_gmt":"2024-06-15T04:02:08","slug":"%e8%ae%b2%e5%a0%82-%e5%85%8d%e7%96%ab%e6%a3%80%e6%9f%a5%e7%82%b9%e6%8a%91%e5%88%b6%e5%89%82%e6%b2%bb%e7%96%97%ef%bc%9actla-4%e5%92%8cpd-1","status":"publish","type":"post","link":"http:\/\/zydq.1006ss.com\/?p=37110","title":{"rendered":"\u8bb2\u5802 | \u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\u6cbb\u7597\uff1aCTLA-4\u548cPD-1"},"content":{"rendered":"

\u514d\u75ab\u6cbb\u7597<\/p>\n

\u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\u6cbb\u7597<\/p>\n

\u4e0e\u624b\u672f\u3001\u653e\u7597\u548c\u5316\u7597\u7b49\u4f20\u7edf\u7684\u6cbb\u7597\u624b\u6bb5\u76f8\u6bd4\uff0c\u80bf\u7624\u514d\u75ab\u6cbb\u7597\u5177\u6709\u7279\u5f02\u6027\u5f3a\uff0c\u526f\u4f5c\u7528\u5c0f\u7684\u4f18\u70b9\u3002\u4ee5T\u6dcb\u5df4\u7ec6\u80de\u4e3a\u57fa\u7840\u7684\u80bf\u7624\u514d\u75ab\u6cbb\u7597\u5df2\u7ecf\u6210\u4e3a\u5bf9\u6297\u764c\u75c7\u7684\u5f3a\u6709\u529b\u5de5\u5177\uff0c\u5176\u4e2d\uff0c\u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\u6cbb\u7597\u662f\u5e7f\u6cdb\u5e94\u7528\u5728\u4e34\u5e8a\u4e0a\u7684\u80bf\u7624\u514d\u75ab\u6cbb\u7597\u65b9\u6cd5\u4e4b\u4e00\u3002<\/p>\n

CTLA-4\u548cPD-1\u751f\u7269\u5b66\u4e0a\u88ab\u79f0\u4f5c\u201c\u514d\u75ab\u68c0\u67e5\u70b9\u201d\uff0c\u662f\u6700\u53d7\u5173\u6ce8\u4e14\u6700\u6709\u6548\u7684T\u7ec6\u80de\u514d\u75ab\u68c0\u67e5\u70b9\u5206\u5b50\uff0c\u53d1\u6325\u7740\u8d1f\u514d\u75ab\u8c03\u8282\u4f5c\u7528\uff0c\u53ef\u4ece\u4e0a\u56fe-1\u53ef\u89c1\u5728\u514d\u75ab\u6062\u590d\u8fc7\u7a0bT\u7ec6\u80de\u7ecf\u5386\u7684\u53d8\u5316\u53ca\u5176\u4f5c\u7528\u673a\u5236\u3002\u4e00\u8d77\u6765\u4e86\u89e3\u4e0b\uff01<\/p>\n

*01CTLA-4\u548cPD-1<\/p>\n

\u80bf\u7624\u514d\u75ab\u6cbb\u7597\u662f\u6307\u5916\u6e90\u5e72\u9884\u673a\u4f53\u514d\u75ab\u7cfb\u7edf\uff0c\u91cd\u65b0\u542f\u52a8\u5e76\u7ef4\u6301\u201c\u80bf\u7624-\u514d\u75ab\u201d\u5faa\u73af\uff0c\u6062\u590d\u3001\u63d0\u9ad8\u673a\u4f53\u7684\u6297\u80bf\u7624\u514d\u75ab\u53cd\u5e94\uff0c\u52a0\u5f3a\u5bf9\u80bf\u7624\u7ec6\u80de\u7684\u8bc6\u522b\u548c\u6740\u4f24\u80fd\u529b\uff0c\u4ece\u800c\u8fbe\u5230\u63a7\u5236\u751a\u81f3\u7279\u5f02\u6027\u6e05\u9664\u80bf\u7624\u7684\u6cbb\u7597\u6548\u679c\u3002<\/p>\n

\u514d\u75ab\u7cfb\u7edf\u4e2d\uff0c\u8d1f\u5411\u8c03\u63a7T\u6dcb\u5df4\u7ec6\u80de\u6fc0\u6d3b\u7684\u56e0\u5b50\u79f0\u4e3a\u514d\u75ab\u68c0\u67e5\u70b9\u5206\u5b50\uff0c\u514d\u75ab\u68c0\u67e5\u70b9\u5206\u5b50\u5728\u9650\u5236\u673a\u4f53\u514d\u75ab\u7cfb\u7edf\u8fc7\u5ea6\u6fc0\u6d3b\u3001\u7ef4\u6301\u673a\u4f53\u514d\u75ab\u7a33\u6001\u8fc7\u7a0b\u4e2d\u53d1\u6325\u91cd\u8981\u4f5c\u7528\u3002\u7ec6\u80de\u6bd2\u6027T\u6dcb\u5df4\u7ec6\u80de\u6297\u539f4\uff08Cytotoxic T lymphocyte antigen 4, CTLA4\uff09\u548c\u7a0b\u5e8f\u6027\u7ec6\u80de\u6b7b\u4ea11\uff08Programmed cell death 1, PD-1\uff09\u662f\u6700\u53d7\u5173\u6ce8\u4e14\u6700\u6709\u6548\u7684T\u7ec6\u80de\u514d\u75ab\u68c0\u67e5\u70b9\u5206\u5b50\u3002\uff08\u56fe-2\uff09<\/p>\n<\/p>\n

\u56fe-2 CTLA4\u548cPD1\u53c2\u4e0eT\u6dcb\u5df4\u7ec6\u80de\u8c03\u8282 T\u7ec6\u80de\u6d3b\u5316\u7684\u521d\u59cb\u4fe1\u53f7\u662fTCR\u5206\u5b50\u8bc6\u522b\u5e76\u7ed3\u5408MHC\u5206\u5b50\u9012\u5448\u7684\u6297\u539f\uff0c\u540c\u65f6\u5728\u5171\u523a\u6fc0\u4fe1\u53f7\uff08B7-1\u548cB7-2\uff09\u7684\u4f5c\u7528\u4e0b\u6d3b\u5316\u3001\u589e\u6b96\u3002\u5728\u6dcb\u5df4\u7ec4\u7ec7\u5185\uff0c\u968f\u7740T\u7ec6\u80de\u7684\u6d3b\u5316\u548c\u589e\u6b96\uff0c\u8f6c\u79fb\u81f3\u819c\u8868\u9762\u7684CTLA4\u5206\u5b50\u589e\u52a0\uff0cB7\u7ed3\u5408CTLA4\u4ea7\u751f\u7684\u6291\u5236\u4fe1\u53f7\u9010\u6e10\u5360\u4e3b\u5bfc\u5730\u4f4d\uff0c\u4ee5\u9632\u6b62\u514d\u75ab\u5e94\u7b54\u8fc7\u5f3a\u800c\u9020\u6210\u514d\u75ab\u635f\u4f24\uff1b\u5728\u5916\u5468\u7ec4\u7ec7\u5185\u7684T\u6dcb\u5df4\u7ec6\u80de\u4e2dPD1\u8868\u8fbe\u91cf\u9010\u6e10\u4e0a\u5347\uff0c\u4e0e\u5176\u914d\u4f53 PDL1\/L2\u7ed3\u5408\uff0c\u8bf1\u53d1T\u7ec6\u80de\u8017\u7aed\uff0c\u7ef4\u6301\u514d\u75ab\u673a\u4f53\u514d\u75ab\u8010\u53d7\u3002<\/p>\n

CTLA4\u5206\u5b50\u901a\u5e38\u8868\u8fbe\u4e8eCD4+\u548cCD8+ T\u7ec6\u80de\u8868\u9762\uff0c\u80fd\u591f\u4e0e\u6297\u539f\u9012\u5448\u7ec6\u80de\uff08Antigen presenting cells, APCs\uff09\u4e0a\u7684B7\u914d\u4f53\u9ad8\u4eb2\u548c\u529b\u7ed3\u5408\uff0c\u4ea7\u751f\u6291\u5236T\u7ec6\u80de\u6d3b\u5316\u7684\u4fe1\u53f7\uff0c\u51cf\u5c11\u7ec6\u80de\u56e0\u5b50\u4ea7\u751f\uff0c\u964d\u4f4e\u673a\u4f53\u6297\u80bf\u7624\u514d\u75ab\u53cd\u5e94\u3002<\/p>\n

\u4f7f\u7528CTLA4\u5206\u5b50\u6291\u5236\u5242\u6216CTLA4\u5355\u514b\u9686\u6297\u4f53\u53ef\u4ee5\u89e3\u9664CTLA4\u5bf9T\u7ec6\u80de\u7684\u6291\u5236\u4f5c\u7528\uff0c\u63d0\u9ad8T\u6dcb\u5df4\u7ec6\u80de\u5bf9\u80bf\u7624TAAs\u5e94\u7b54\u6c34\u5e73\uff0c\u589e\u5f3a\u673a\u4f53\u514d\u75ab\u7ec6\u80de\u7684\u6297\u80bf\u7624\u6548\u5e94\uff08\u56fe-3\uff09\u3002<\/p>\n<\/p>\n

\u56fe-3 CTLA4\u5355\u514b\u9686\u6297\u4f53\u4ecb\u5bfc\u7684\u514d\u75ab\u6cbb\u7597 \u4f7f\u7528CTLA4\u5355\u514b\u9686\u6297\u4f53\u963b\u65ad\u8c03\u8282\u6027T\u7ec6\u80de\u8868\u9762CTLA4\u5206\u5b50\u4e0eFc\u95f4\u7684\u5171\u523a\u6fc0\u4fe1\u53f7\uff0c\u53ef\u8bf1\u53d1\u8c03\u8282\u6027T\u7ec6\u80de\u6b7b\u4ea1\uff1b\u6b64\u5916\uff0cCTLA4\u5355\u514b\u9686\u6297\u4f53\u8fd8\u53ef\u4ee5\u5728T\u7ec6\u80de\u6d3b\u5316\u65f6\u963b\u65adCTLA4\u5206\u5b50\u4e0eB7\u4e4b\u95f4\u7684\u7ed3\u5408\uff0c\u63d0\u9ad8T\u7ec6\u80de\u53c2\u4e0e\u7684\u514d\u75ab\u5e94\u7b54\u3002<\/p>\n

PD-1\u5728T\u6dcb\u5df4\u7ec6\u80de\u6fc0\u6d3b\u6216\u6269\u589e\u671f\u95f4\u8868\u8fbe\uff0c\u53ef\u4ee5\u4e0e\u80bf\u7624\u7ec6\u80de\u6216\u5176\u4ed6\u514d\u75ab\u7ec6\u80de\u4e0a\u7684PD-L1\u3001\u5de8\u566c\u7ec6\u80de\u548c\u6811\u7a81\u72b6\u7ec6\u80de\u4e0a\u7684PD-L2\u7ed3\u5408\uff0c\u6291\u5236\u7ec6\u80de\u5185\u4fe1\u53f7\u4f20\u5bfc\uff0c\u964d\u4f4e\u6548\u5e94T\u6dcb\u5df4\u7ec6\u80de\u6d3b\u6027\uff0c\u8bf1\u5bfcT\u6dcb\u5df4\u7ec6\u80de\u51cb\u4ea1\uff0c\u8d1f\u5411\u8c03\u63a7\u673a\u4f53\u6297\u80bf\u7624\u514d\u75ab\u53cd\u5e94\uff0c\u6700\u7ec8\u4f7f\u80bf\u7624\u7ec6\u80de\u53d1\u751f\u514d\u75ab\u9003\u9038\u3002<\/p>\n

\u4f7f\u7528PD-1\u6216\u8005\u5176\u914d\u4f53PD-L1\u3001PD-L2\u5355\u514b\u9686\u6297\u4f53\u9009\u62e9\u6027\u963b\u65ad\u80bf\u7624\u7ec6\u80de\u4e0eT\u7ec6\u80de\u4e4b\u95f4PD-1\u4e0e\u914d\u4f53\u7ed3\u5408\uff0c\u53ef\u4ee5\u6062\u590d\u673a\u4f53\u6297\u80bf\u7624\u514d\u75ab\u529b\uff0c\u540c\u65f6\u589e\u5f3a\u7ec6\u80de\u6bd2\u6027T\u7ec6\u80de\u53c2\u4e0e\u7684\u6eb6\u7624\u4f5c\u7528\uff0c\u8fbe\u5230\u6d88\u9664\u80bf\u7624\u7684\u6548\u679c\u3002\uff08\u56fe-4\uff09<\/p>\n<\/p>\n

\u56fe-4 PD-1\/PD-L\u4ecb\u5bfc\u7684\u514d\u75ab\u6cbb\u7597 \u4f7f\u7528PD1\u6216PDL\u7279\u5f02\u6027\u5355\u514b\u9686\u6297\u4f53\u963b\u65adPD1\u4e0ePDL1\/2\u4e4b\u95f4\u7684\u7ed3\u5408\uff0c\u589e\u5f3a\u7ec6\u80de\u6bd2\u6027T\u7ec6\u80de\u53c2\u4e0e\u7684\u6eb6\u7624\u4f5c\u7528\u3002*02\u836f\u7269\u53ca\u5176\u526f\u4f5c\u7528<\/p>\n

\u591a\u79cd\u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\u836f\u7269\u5df2\u88ab\u6279\u51c6\u4e0a\u5e02\u7528\u4e8e\u4e34\u5e8a\u80bf\u7624\u7684\u514d\u75ab\u6cbb\u7597\uff0c\u5305\u62ec CTLA-4\u5355\u514b\u9686\u6297\u4f53Ipilimumab\uff0cPD-1\u5355\u514b\u9686\u6297\u4f53Nivolumab\u3001Pembrolizumab\uff0cPD-L1\u5355\u514b\u9686\u6297\u4f53Atezolizumab\u3001Avelumab\u7b49\u3002CTLA4\u548cPD-1\u5728\u673a\u4f53\u514d\u75ab\u7cfb\u7edf\u4e2d\u53d1\u6325\u751f\u7269\u5b66\u6548\u5e94\u7684\u90e8\u4f4d\u548c\u65f6\u95f4\u5404\u4e0d\u76f8\u540c\uff0c\u4e24\u8005\u5728\u529f\u80fd\u4e0a\u76f8\u4e92\u8865\u5145\uff0c\u786e\u4fddT\u6dcb\u5df4\u7ec6\u80de\u53cd\u5e94\u6709\u6548\u4fdd\u62a4\u673a\u4f53\u514d\u53d7\u80bf\u7624\u7ec6\u80de\u4fb5\u5bb3\u7684\u540c\u65f6\u4fdd\u6301\u9002\u5f53\u6c34\u5e73\u81ea\u6211\u8010\u53d7\u3002<\/p>\n

\u4f46\u662f\uff0c\u4f7f\u7528\u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\u53ef\u4ee5\u653e\u5927\u514d\u75ab\u6548\u5e94\uff0c\u6270\u4e71\u673a\u4f53\u6b63\u5e38\u7684\u514d\u75ab\u8010\u53d7\u80fd\u529b\u3002\u4e34\u5e8a\u5e94\u7528\u4e2d\uff0cT\u6dcb\u5df4\u7ec6\u80de\u524d\u4f53\u7ec6\u80de\u7684\u4e27\u5931\u3001\u8fc7\u5ea6\u6d3b\u5316\u7684\u8bb0\u5fc6T\u7ec6\u80de\u79ef\u7d2f\u662f\u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\u6cbb\u7597\u526f\u4f5c\u7528\u7684\u5171\u540c\u7279\u70b9\uff0c\u8fc7\u5ea6\u6d3b\u5316\u7684T\u6dcb\u5df4\u7ec6\u80de\u5165\u4fb5\u80c3\u80a0\u9053\u3001\u80ba\u7b49\u5668\u5b98\uff0c\u5f15\u8d77\u673a\u4f53\u6b63\u5e38\u7ec6\u80de\u7684\u514d\u75ab\u75c5\u7406\u635f\u4f24\u3002<\/p>\n

\u4f7f\u7528CTLA4\u5355\u514b\u9686\u6297\u4f53\u6cbb\u7597\u7684\u526f\u4f5c\u7528\u4e3b\u8981\u8868\u73b0\u4e3a\u80c3\u80a0\u9053\u635f\u4f24\u548c\u5927\u8111\u5185\u795e\u7ecf\u7cfb\u7edf\u635f\u4f24\uff1b\u800c\u4f7f\u7528PD1\u6216\u5176\u914d\u4f53\u5355\u514b\u9686\u6297\u4f53\u6cbb\u7597\u7684\u60a3\u8005\u53d1\u751f\u7532\u72b6\u817a\u529f\u80fd\u51cf\u9000\u3001\u809d\u6bd2\u6027\u548c\u80ba\u708e\u7684\u98ce\u9669\u66f4\u9ad8\u3002\u4e3a\u4e86\u66f4\u5b8c\u5584\u7684\u5e94\u5bf9\u4e34\u5e8a\u5e94\u7528\u4e2d\u4f7f\u7528\u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\u5f15\u8d77\u7684\u526f\u4f5c\u7528\uff0c\u901a\u8fc7\u4fee\u9970\u5355\u514b\u9686\u6297\u4f53\u3001\u4f7f\u7528\u65b0\u578b\u6297\u4f53\u8f6c\u8fd0\u8f7d\u4f53\uff0c\u6216\u7b5b\u9009\u8bc6\u522b\u514d\u75ab\u68c0\u67e5\u70b9\u6cbb\u7597\u5f15\u8d77\u7684\u5668\u5b98\u7279\u5f02\u6027\u6bd2\u6027\u7684\u9884\u6d4b\u6027\u751f\u7269\u6807\u5fd7\u7269\uff0c\u4ee5\u8fbe\u5230\u51cf\u5f31\u6216\u53ca\u65f6\u5e94\u5bf9\u4e34\u5e8a\u6cbb\u7597\u8fc7\u7a0b\u4e2d\u7684\u4e0d\u826f\u53cd\u5e94\u3002<\/p>\n

\u53c2\u8003\u8d44\u6599\uff1a<\/p>\n

1.GRaice\uff0c\u5fae\u4fe1\u516c\u4f17\u53f7\u201cBiG\u751f\u7269\u521b\u65b0\u793e\u201d\uff0c2022-05-21\uff0c\u300a\u7efc\u8ff0\uff5c\u80bf\u7624\u514d\u75ab\u7597\u6cd5\u6c47\u603b\u300b<\/p>\n

2. kennisy\uff0c\u5fae\u4fe1\u516c\u4f17\u53f7\u201c\u533b\u836f\u901f\u89c8\u201d\uff0c2021-11-09\uff0c\u300a\u4eba\u4eba\u5b66\u61c2\u514d\u75ab\u5b66\u7b2c\u4e09\u5341\u671f\uff1a\u514d\u75ab\u6062\u590d\u8fc7\u7a0bT\u7ec6\u80de\u7ecf\u5386\u7684\u53d8\u5316\u53ca\u5176\u4f5c\u7528\u673a\u5236\u300b<\/p>\n

\u514d\u75ab\u6cbb\u7597\u00b7 \u66f4\u591a\u4e86\u89e3> \u8d75\u519b\u4e3b\u4efb\uff1a2021\u80ba\u764c\u514d\u75ab\u6cbb\u7597\u65b0\u8fdb\u5c55> \u8d75\u519b\u4e3b\u4efb\uff1a\u80ba\u764c\u514d\u75ab\u6cbb\u7597\u600e\u4e48\u6837\uff1f> \u8fdf\u96e8\u4f73\u533b\u751f\uff1a\u5982\u4f55\u9762\u5bf9\u514d\u75ab\u6cbb\u7597\u7684\u7591\u8651\uff1f> \u8fdf\u96e8\u4f73\u533b\u751f\uff1a\u80ba\u764c\u6cbb\u7597\u514d\u75ab\u4e0d\u826f\u53cd\u5e94\u7684\u5e94\u5bf9> 2021\u5e74\u80ba\u51e1\u533b\u8bdd\uff1a\u514d\u75ab\u4e2d\u9752\u5e74\u4e13\u5bb6\u6c99\u9f99” data-itemshowtype=”0″ tab=”innerlink” data-linktype=”2″ wah-hotarea=”click” hasload=”1″ style=”font-size: 13px; outline: 0px; -webkit-tap-highlight-color: rgba(0, 0, 0, 0); cursor: pointer; max-width: 100%; widows: 1; font-family: -apple-system-font, BlinkMacSystemFont, Arial, sans-serif; letter-spacing: normal; visibility: visible; box-sizing: border-box !important; overflow-wrap: break-word !important;”>> 2021\u5e74\u80ba\u51e1\u533b\u8bdd\uff1a\u514d\u75ab\u4e2d\u9752\u5e74\u4e13\u5bb6\u6c99\u9f99> 2021\u5e74\u80ba\u51e1\u533b\u8bdd\uff1a\u4eac\u6d25\u5180\u80bf\u7624\u514d\u75ab\u6cbb\u7597\u591a\u5b66\u79d1\u4e13\u5bb6\u4f1a\u8c08” data-itemshowtype=”0″ tab=”innerlink” data-linktype=”2″ wah-hotarea=”click” hasload=”1″ style=”font-size: 13px; outline: 0px; -webkit-tap-highlight-color: rgba(0, 0, 0, 0); cursor: pointer; max-width: 100%; caret-color: red; letter-spacing: normal; visibility: visible; box-sizing: border-box !important; overflow-wrap: break-word !important;”>> 2021\u5e74\u80ba\u51e1\u533b\u8bdd\uff1a\u4eac\u6d25\u5180\u80bf\u7624\u514d\u75ab\u6cbb\u7597\u591a\u5b66\u79d1\u4e13\u5bb6\u4f1a\u8c08<\/p>\n

\u7f16\u8f91 | \u5c0f\u536b\uff1b\u6392\u7248 | \u5c0f\u5065<\/p>\n

\u90e8\u5206\u56fe\u6587\u89c6\u9891\u6e90\u81ea\u7f51\u7edc\uff1b\u82e5\u6709\u5f02\u8bae\u6216\u4fb5\u6743\uff0c\u8bf7\u8054\u7cfb\u5220\u9664\u3002<\/p>\n

\u672c\u8d44\u6599\u4ec5\u4f9b\u4ea4\u6d41\u53c2\u8003\uff1b\u82e5\u5e0c\u671b\u4e86\u89e3\u66f4\u591a\u76f8\u5173\u4fe1\u606f\uff0c\u8bf7\u54a8\u8be2\u4e13\u4e1a\u533b\u52a1\u5de5\u4f5c\u8005\u6216\u524d\u5f80\u6b63\u89c4\u533b\u9662\u5c31\u8bca\u3002<\/p>\n

\u66f4\u591a\u7f16\u8f91<\/p>\n

\u6295\u7a3f\/\u5408\u4f5c\uff1a6900904@qq.com\uff0c\u5fae\u4fe118500776078<\/p>\n

– END -\u5fae\u4fe1\u89c6\u9891\u53f7\u2193  \u70b9\u51fb \u9605\u8bfb\u539f\u6587 \u8fdb\u5165\u5927\u4f17\u7248\u6216\u4e13\u4e1a\u7248\uff0c\u638c\u63e1\u66f4\u591a\uff01<\/p>\n","protected":false},"excerpt":{"rendered":"

\u514d\u75ab\u6cbb\u7597 \u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\u6cbb\u7597 \u4e0e\u624b\u672f\u3001\u653e\u7597\u548c\u5316\u7597\u7b49\u4f20\u7edf\u7684\u6cbb\u7597\u624b\u6bb5\u76f8\u6bd4\uff0c\u80bf\u7624\u514d\u75ab … \u7ee7\u7eed\u9605\u8bfb →<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[70],"tags":[],"class_list":["post-37110","post","type-post","status-publish","format-standard","hentry","category-70"],"_links":{"self":[{"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=\/wp\/v2\/posts\/37110","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=37110"}],"version-history":[{"count":0,"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=\/wp\/v2\/posts\/37110\/revisions"}],"wp:attachment":[{"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=37110"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=37110"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=37110"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}