{"id":36835,"date":"2024-06-12T12:01:02","date_gmt":"2024-06-12T12:01:02","guid":{"rendered":"https:\/\/zydq.1006ss.com\/?p=36835"},"modified":"2024-06-12T12:01:02","modified_gmt":"2024-06-12T12:01:02","slug":"%e8%a1%80%e7%ae%a1%e5%91%a8%e4%b8%8a%e7%9a%ae%e6%a0%b7%e7%bb%86%e8%83%9e%e8%82%bf%e7%98%a4%ef%bc%88pecoma%e5%ae%b6%e6%97%8f%ef%bc%89","status":"publish","type":"post","link":"http:\/\/zydq.1006ss.com\/?p=36835","title":{"rendered":"\u8840\u7ba1\u5468\u4e0a\u76ae\u6837\u7ec6\u80de\u80bf\u7624\uff08PEcoma\u5bb6\u65cf\uff09"},"content":{"rendered":"

1.\u5b9a\u4e49\uff1aPEcoma\u662f\u4e00\u79cd\u95f4\u53f6\u6e90\u6027\u80bf\u7624\uff0c\u7624\u7ec6\u80de\u663e\u793a\u4e0e\u8840\u7ba1\u58c1\u6709\u5c40\u90e8\u76f8\u5173\u6027\uff0c\u901a\u5e38\u8868\u8fbe\u8272\u7d20\u6807\u8bb0\uff08HMB45\uff09\u4e0e\u5e73\u6ed1\u808c\u6807\u8bb0\uff08desmin\uff09\u3002<\/p>\n

2.PEcoma\u5bb6\u65cf\u5305\u62ec\uff1a<\/p>\n

(1)\u8840\u7ba1\u5e73\u6ed1\u808c\u8102\u80aa\u7624\uff08AML\uff09\uff1a\u597d\u53d1\u4e8e\u809d\u80be\uff0c\u53ef\u4f34TSC\uff1b<\/p>\n

(2)\u7cd6\u7624\uff08CCST\uff09\uff1a\u597d\u53d1\u4e8e\u80ba\uff0c\u53ef\u4f34TSC\uff1b<\/p>\n

(3)\u6dcb\u5df4\u7ba1\u808c\u7624\u75c5\uff08LAM\uff09\uff1a\u597d\u53d1\u4e8e\u80ba\u548c\u76c6\u8154\uff0c\u53ef\u4f34TSC\uff1b<\/p>\n

(4)PEcoma\u975e\u7279\u6307<\/p>\n

*TSC\uff1a\u7ed3\u8282\u786c\u5316\u7efc\u5408\u5f81\uff0c\u662f\u4e00\u79cd\u5e38\u67d3\u8272\u4f53\u663e\u6027\u9057\u4f20\u75c5\uff0c\u4e34\u5e8a\u8868\u73b0\u4e3a\u76ae\u80a4\u786c\u7ed3\uff0c\u53d1\u80b2\u8fdf\u7f13\u3001\u766b\u75eb\u7b49\u3002<\/p>\n

3.\u955c\u4e0b\uff1a<\/p>\n

(1)\u4f4e\u500d\u955c\u4e0b\uff0c\u80bf\u7624\u7ec6\u80de\u6392\u5217\u6210\u5de2\u72b6\u3001\u6881\u72b6\u3001\u7247\u72b6\uff0c\u4e0e\u5927\u8840\u7ba1\u5bc6\u5207\u76f8\u5173\uff0c\u6cbf\u8840\u7ba1\u58c1\u5448\u653e\u5c04\u72b6\u6392\u5217\uff1b<\/p>\n<\/p>\n

(2)\u9ad8\u500d\u955c\u4e0b\uff0c\u80bf\u7624\u7ec6\u80de\u5448\u4e0a\u76ae\u6837\u3001\u68ad\u5f62\u6216\u8718\u86db\u6837\u7ec6\u80de\uff0c\u80de\u6d46\u900f\u4eae\u6216\u55dc\u9178\uff0c\u6709\u9897\u7c92\u611f\uff1b<\/p>\n

(3)TFE3\u91cd\u6392\u7684PEcoma\u4e3a\u900f\u660e\u80de\u6d46\u3002<\/p>\n

4.HE\u56fe\u7247\uff1a<\/p>\n

(1)\u8840\u7ba1\u5e73\u6ed1\u808c\u8102\u80aa\u7624\uff08AML\uff09\uff1a<\/p>\n<\/p>\n

(2)\u7cd6\u7624\uff08CCST\uff09\uff1a<\/p>\n<\/p>\n

(3)\u6dcb\u5df4\u7ba1\u808c\u7624\u75c5\uff08LAM\uff09\uff1a<\/p>\n<\/p>\n

5.\u514d\u75ab\u7ec4\u5316\uff1a\u8868\u8fbeHMB45\u3001desmin\u3001SMA\uff1b\u4e0d\u8868\u8fbeS-100\u3002<\/p>\n

6.\u5206\u5b50\uff1a<\/p>\n

(1)TSC\u7f3a\u5931\uff1a\u53ef\u7528mTOR\u6291\u5236\u5242\uff08\u897f\u7f57\u83ab\u53f8\uff09\u6cbb\u7597\uff1b<\/p>\n

(2)TFE3\u57fa\u56e0\u878d\u5408\u3002<\/p>\n

7.\u4e0a\u76ae\u6837PEcoma\u7279\u70b9<\/p>\n<\/p>\n

(1)\u662f\u4e00\u79cd\u6076\u6027\u6f5c\u80fd\u4e0d\u5b9a\u7684\u80bf\u7624\uff0c\u53ef\u4f34\u9ad3\u5916\u9020\u8840\uff1b<\/p>\n

(2)\u955c\u4e0b\uff1a\u4e0a\u76ae\u6837\u7ec6\u80de\u5f62\u6001\uff0c\u8718\u86db\u6837\u7ec6\u80de\uff1b<\/p>\n

(3)\u53d1\u751f\u4e8e\u80be\u810f\u65f6\uff0c\u4e0a\u76ae\u6837\u7ec6\u80de\u9700\u226780%\u624d\u53ef\u8bca\u65ad\uff0c\u6ce8\u610f\u4e0e\u80be\u764c\u9274\u522b\uff1b<\/p>\n

(4)\u53d1\u751f\u4e8e\u809d\u810f\u65f6\uff0c\u4e0a\u76ae\u6837\u7ec6\u80de\u9700\u226750%\u624d\u53ef\u8bca\u65ad\uff0c\u6ce8\u610f\u4e0e\u809d\u7ec6\u80de\u809d\u764c\u9274\u522b\uff1b<\/p>\n

8.PEcoma\u53d8\u5f02\u578b\uff1a<\/p>\n

(1)\u786c\u5316\u6027PEcoma\uff1a\u95f4\u8d28\u786c\u5316\uff0c\u4e0eTSC\u65e0\u5173\uff1b<\/p>\n

(2)\u7ea4\u7ef4\u7624\u6837PEcoma\uff1a\u4ee5\u68ad\u5f62\u7ec6\u80de\u4e3a\u4e3b\uff1b<\/p>\n

9.\u6076\u6027PEcoma\u7684\u8bca\u65ad\u6807\u51c6\uff1a<\/p>\n

(1)>5cm\uff1b<\/p>\n

(2)\u8fb9\u754c\u6d78\u6da6\uff1b<\/p>\n

(3)\u9ad8\u7ea7\u522b\u6838\uff1b<\/p>\n

(4)\u80bf\u7624\u6027\u574f\u6b7b\uff1b<\/p>\n

(5)\u6838\u5206\u88c2>1\u4e2a\/50HPFs\uff1b<\/p>\n

(6)\u8840\u7ba1\u4fb5\u72af\uff1b<\/p>\n

(7)2\u6761\u4ee5\u4e0a\u53ef\u8ba4\u5b9a\u4e3a\u6076\u6027\u3002<\/p>\n

10.PEcoma\u5bb6\u65cf\u9884\u540e\uff1a<\/p>\n

(1)\u8840\u7ba1\u5e73\u6ed1\u808c\u8102\u80aa\u7624\uff08AML\uff09\uff1a\u53d1\u751f\u4e8e\u80be\u7684AML\u5448\u6d78\u6da6\u6027\u751f\u957f\uff0c\u53ef\u590d\u53d1\uff0c\u4f34TSC\u65f6\u63d0\u793a\u9884\u540e\u4e0d\u826f\uff1b\u53d1\u751f\u4e8e\u80be\u5916\u7684AML\u4e3a\u826f\u6027\uff1b<\/p>\n

(2)\u7cd6\u7624\uff08CCST\uff09\uff1a\u9884\u540e\u8f83\u597d\uff1b<\/p>\n

(3)\u6dcb\u5df4\u7ba1\u808c\u7624\u75c5\uff08LAM\uff09\uff1a\u5c40\u9650\u6027\u75c5\u53d8\u5207\u9664\u540e\u53ef\u957f\u671f\u751f\u5b58\uff1b\u5e7f\u6cdb\u7d2f\u53ca\u8005\u53ef\u81f4\u6b7b\uff1b<\/p>\n","protected":false},"excerpt":{"rendered":"

1.\u5b9a\u4e49\uff1aPEcoma\u662f\u4e00\u79cd\u95f4\u53f6\u6e90\u6027\u80bf\u7624\uff0c\u7624\u7ec6\u80de\u663e\u793a\u4e0e\u8840\u7ba1\u58c1\u6709\u5c40\u90e8\u76f8\u5173\u6027\uff0c\u901a\u5e38\u8868 … \u7ee7\u7eed\u9605\u8bfb →<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[70],"tags":[],"class_list":["post-36835","post","type-post","status-publish","format-standard","hentry","category-70"],"_links":{"self":[{"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=\/wp\/v2\/posts\/36835","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=36835"}],"version-history":[{"count":0,"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=\/wp\/v2\/posts\/36835\/revisions"}],"wp:attachment":[{"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=36835"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=36835"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=36835"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}