{"id":33449,"date":"2024-05-12T04:01:27","date_gmt":"2024-05-12T04:01:27","guid":{"rendered":"https:\/\/zydq.1006ss.com\/?p=33449"},"modified":"2024-05-12T04:01:27","modified_gmt":"2024-05-12T04:01:27","slug":"%e7%bb%84%e7%bb%87%e5%ad%a6%e4%b8%8e%e7%97%85%e7%90%86%e5%ad%a6%ef%bc%9a%e7%bb%93%e7%bc%94%e7%bb%84%e7%bb%871%ef%bc%88%e5%9b%ba%e6%9c%89%e7%bb%93%e7%bc%94%e7%bb%84%e7%bb%87%ef%bc%9a%e7%96%8f%e6%9d%be","status":"publish","type":"post","link":"http:\/\/zydq.1006ss.com\/?p=33449","title":{"rendered":"\u7ec4\u7ec7\u5b66\u4e0e\u75c5\u7406\u5b66\uff1a\u7ed3\u7f14\u7ec4\u7ec71\uff08\u56fa\u6709\u7ed3\u7f14\u7ec4\u7ec7\uff1a\u758f\u677e\u7ed3\u7f14\u7ec4\u7ec7\uff09"},"content":{"rendered":"

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1 \u5f39\u6027\u7ea4\u7ef4 2 \u8102\u80aa\u7ec6\u80de 3 \u6d46\u7ec6\u80de 4 \u80f6\u539f\u7ea4\u7ef4 5 \u5de8\u566c\u7ec6\u80de 6 \u80a5\u5927\u7ec6\u80de 7\u95f4\u8d288 \u6210\u7ea4\u7ef4\u7ec6\u80de<\/p>\n<\/p>\n

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1 \u6210\u7ea4\u7ef4\u7ec6\u80de\uff08\u6d3b\u8dc3\uff09\u548c\u7ea4\u7ef4\u7ec6\u80de\uff08\u9759\u6b62\uff09<\/p>\n<\/p>\n

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\u6210\u7ea4\u7ef4\u7ec6\u80de\uff08fibroblast\uff09\uff1a<\/p>\n

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\u7ea4\u7ef4\u7ec6\u80de\uff08fibrocyte\uff09\uff1a<\/p>\n

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\u808c\u6210\u7ea4\u7ef4\u7ec6\u80de\uff08myofibroblast,Mf)<\/p>\n

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\u80fd\u5f15\u8d77\u6536\u7f29\u7684\u7269\u8d28\uff1a5-\u7f9f\u8272\u80fa\uff085-hydroxytryptamine\uff0c5-HT\uff09\uff0c\u8840\u7ba1\u7d27\u5f20\u80bd\u3001\u8840\u7ba1\u52a0\u538b\u7d20\uff08vasopressin\uff0c VP \uff09\u53c8\u79f0\u6297\u5229\u5c3f\u6fc0\u7d20\uff08antidiuretic hormone\uff0c ADH \uff09\u3001\u80be\u4e0a\u817a\u7d20\uff08adrenaline\uff09\u3001\u53bb\u7532\u80be\u4e0a\u817a\u7d20\uff08Norepinephrine\uff0cNoradrenaline\uff09\u3001\u7f13\u6fc0\u80bd (bradykinin,BK)\uff0c\u524d\u5217\u817a\u7d20\uff08prostaglandin\uff09Ela\uff1b<\/p>\n

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2 \u5de8\u566c\u7ec6\u80de\uff08\u6d3b\u8dc3\uff09\u6216\u7ec4\u7ec7\u7ec6\u80de\uff08\u9759\u6b62\uff09<\/p>\n

\u5de8\u566c\u7ec6\u80de\uff08Macrophages\uff09\uff1a\u5e38\u4f38\u51fa\u8f83\u957f\u7684\u4f2a\u8db3\uff0c\u5f62\u6001\u4e0d\u89c4\u5219\u3002\u7ec6\u80de\u6838\u8f83\u5c0f\uff0c\u5706\u5f62\u6216\u80be\u5f62\uff0c\u8272\u6df1\uff1b\u7ec6\u80de\u8d28\u4e30\u5bcc\uff0c\u55dc\u9178\u6027\uff0c\u53ef\u6709\u5f02\u7269\u9897\u7c92\u6216\u7a7a\u6ce1\u3002<\/p>\n

\u7535\u955c\u4e0b\uff0c\u7ec6\u80de\u8868\u9762\u6709\u76b1\u8936\u3001\u5fae\u7ed2\u6bdb\u548c\u5c11\u6570\u7403\u5f62\u9686\u8d77\uff0c\u7ec6\u80de\u8d28\u6709\u5927\u91cf\u6eb6\u9176\u4f53\u3001\u541e\u566c\u4f53\u3001\u541e\u996e\u6ce1\u548c\u6b8b\u4f59\u4f53\u53ca\u6570\u91cf\u4e0d\u7b49\u7684\u7c97\u9762\u5185\u8d28\u7f51\u3001\u9ad8\u5c14\u57fa\u590d\u5408\u4f53\u548c\u7ebf\u7c92\u4f53\u3002\u7ec6\u80de\u5185\u4fa7\u548c\u4f2a\u8db3\u5185\u6709\u8f83\u591a\u5fae\u4e1d\u548c\u5fae\u7ba1<\/p>\n

\u5de8\u566c\u7ec6\u80de\u5206\u4e24\u7c7b\uff1a<\/p>\n

\u7ec4\u7ec7\u7ec6\u80de\uff08histocyte)\uff1a\u758f\u677e\u7ed3\u7f14\u7ec4\u7ec7\u5185\u5b9a\u5c45\u7684\u4f11\u6b62\u5de8\u566c\u7ec6\u80de\uff0c\u666e\u901a\u5207\u7247\u4e0a\u4e0d\u6613\u4e0e\u6210\u7ea4\u7ef4\u7ec6\u80de\u533a\u522b\u3002\u5f62\u6001\u4e0d\u89c4\u5219\uff0c\u591a\u5448\u661f\u5f62\u6216\u68ad\u5f62\uff0c\u7ec6\u80de\u6838\u5e38\u6709\u51f9\u9677\uff0c\u5375\u5706\u5f62\u6216\u80be\u5f62\uff0c\u6bd4\u6210\u7ea4\u7ef4\u7ec6\u80de\u7565\u5c0f\uff0c\u67d3\u8272\u8d28\u8f83\u6d53\u5bc6\uff0c\u6545\u6838\u67d3\u8272\u6df1\uff0c\u6838\u4ec1\u4e0d\u660e\u663e\u3002\u7ec6\u80de\u8d28\u4e30\u5bcc\uff0c\u55dc\u9178\u6027\uff0c\u542b\u6709\u5f88\u591a\u5c0f\u9897\u7c92\u548c\u7a7a\u6ce1\u3002\u7ec4\u5316\u53ef\u663e\u793a\u7ec6\u80de\u8d28\u5185\u7684\u975e\u7279\u5f02\u6027\u916f\u9176\u548c\u6eb6\u9176\u4f53\u9176\uff08\u9178\u6027\u78f7\u9178\u9176\u3001\u8461\u7cd6\u919b\u9178\u3001\u82b3\u9999\u57fa\u786b\u9178\u916f\u9176\u3001\u6eb6\u83cc\u9176\u7b49\uff09\u3002\u4ee5\u53f0\u76fc\u84dd\u3001\u5361\u7ea2\u6216\u58a8\u6c41\u6ce8\u5c04\u5b9e\u9a8c\u52a8\u7269\u4f53\u5185\u4f5c\u6d3b\u4f53\u67d3\u8272\uff0c\u53ef\u89c1\u5de8\u566c\u7ec6\u80de\u80de\u8d28\u5185\u6709\u5f88\u591a\u84dd\u8272\u3001\u7ea2\u8272\u6216\u9ed1\u8272\u9897\u7c92\u3002\u6210\u7ea4\u7ef4\u7ec6\u80de\u548c\u5176\u4ed6\u7ec6\u80de\u4e0d\u6444\u53d6\u6216\u5f88\u5c11\u6444\u53d6\u67d3\u6599\u9897\u7c92\uff0c\u7528\u5355\u514b\u9686\u6297\u4f53\u514d\u75ab\u7ec6\u80de\u5316\u5b66\u663e\u793a\u5de8\u566c\u7ec6\u80de\u8868\u9762\u6297\u539f\uff0c\u53ef\u51c6\u786e\u9274\u522b\u5de8\u566c\u7ec6\u80de\u3002<\/p>\n

\u6e38\u8d70\u7684\u5de8\u566c\u7ec6\u80de\uff1a\u5927\u5c0f\u4e0d\u4e00\uff0c\u76f4\u5f8420~50\u03bcm\uff0c\u5f62\u6001\u591a\u6837\uff0c\u7ec6\u80de\u754c\u9650\u6e05\u695a\uff0c\u4f46\u8fb9\u7f18\u5e73\u5766\uff0c\u6709\u949d\u5706\u7a81\u8d77\u3002\u7ec6\u80de\u5375\u5706\u5f62\u3001\u80be\u5f62\u6216\u4e0d\u89c4\u5219\uff0c\u5e38\u504f\u4e8e\u7ec6\u80de\u4e00\u4fa7\uff0c\u5f02\u67d3\u8272\u8d28\u9897\u7c92\u7ec6\u5c0f\uff0c\u5206\u6563\u5728\u672f\u5185\u6216\u9644\u5728\u6838\u819c\u5185\u9762\uff0c\u67091~2\u4e2a\u6838\u4ec1\u3002\u7ec6\u80de\u8f83\u591a\uff0c\u55dc\u9178\u6027\u6216\u5f31\u55dc\u78b1\u6027\uff0c\u89c9\u7a7a\u6ce1\u548c\u88ab\u541e\u566c\u7684\u7edd\u6280<\/p>\n

\u5de8\u566c\u7ec6\u80de\u5206\u4e09\u7c7b\uff1a<\/p>\n

\u5206\u5e03\u4e8e\u4e00\u5b9a\u90e8\u4f4d\u5e76\u672a\u53d7\u5916\u754c\u523a\u6fc0\u7684\u5de8\u566c\u7ec6\u80de\u79f0\u5b9a\u5c45\u7684\u5de8\u566c\u7ec6\u80de\uff1b<\/p>\n

\u5728\u53d7\u523a\u6fc0\u5730\u7684\u4ea7\u751f\u53cd\u5e94\u7684\u6d3b\u52a8\u6027\u5de8\u566c\u7ec6\u80de\uff1b<\/p>\n

\u5bf9\u5c40\u90e8\u523a\u6fc0\u4ea7\u751f\u53cd\u5e94\u5e76\u51fa\u73b0\u541e\u566c\u6d3b\u52a8\u548c\u6297\u539f\u5448\u9012\u6d3b\u52a8\u589e\u5f3a\u7684\u5de8\u566c\u7ec6\u80de\u79f0\u6d3b\u5316\u7684\u5de8\u566c\u7ec6\u80de\u3002<\/p>\n

\u5b9a\u5c45\u7684\u5de8\u566c\u7ec6\u80de\u5e7f\u6cdb\u5206\u5e03\u5728\u7ed3\u7f14\u7ec4\u7ec7\u80f6\u539f\u7ea4\u7ef4\u675f\u4e4b\u95f4\uff0c\u68ad\u5f62\u6216\u661f\u5f62\uff0c\u4e3b\u8981\u5206\u5e03\u5728\u5c0f\u8840\u7ba1\u5468\u56f4\uff0c\u7ec6\u80de\u6838\u8f83\u5c0f\uff0c\u67d3\u8272\u8f83\u6df1\uff1b\u7ec6\u80de\u8d28\u591a\u5448\u5f02\u8d28\u6027\uff0c\u5e38\u542b\u8bb8\u591a\u7a7a\u6ce1\u548c\u5c0f\u7684\u81f4\u5bc6\u9897\u7c92\uff08\u7535\u955c\u4e0b\u4e3a\u521d\u7ea7\u6eb6\u9176\u4f53\u548c\u6b21\u7ea7\u6eb6\u9176\u4f53\uff09\u3002\u53ef\u533a\u522b\u6210\u7ea4\u7ef4\u7ec6\u80de<\/p>\n

\u6e38\u51fa\u7684\u5de8\u566c\u7ec6\u80de\u548c\u6d3b\u5316\u7684\u5de8\u566c\u7ec6\u80de\uff0c\u5f62\u6001\u591a\u53d8\uff0c\u79fb\u52a8\u65f6\u4f38\u51fa\u4f2a\u8db3\uff0c\u8868\u9762\u6709\u8bb8\u591a\u77ed\u7684\u5fae\u7ed2\u6bdb\u548c\u6241\u8db3\uff08lamellipodia\uff09\uff0c\u5448\u6ce2\u6d6a\u5f62\u7684\u7ec6\u5c0f\u76b1\u8936\u3002<\/p>\n

\u7535\u955c\u4e0b\uff0c\u7ec6\u80de\u8868\u9762\u5e38\u6709\u5f88\u591a\u76b1\u895e\u3001\u4e0d\u89c4\u5219\u7684\u5fae\u7ed2\u6bdb\u548c\u5c11\u6570\u7403\u5f62\u9686\u8d77\uff08\u542b\u541e\u566c\u4f53\uff09\uff0c\u5c24\u591a\u89c1\u4e8e\u6e38\u8d70\u7684\u5de8\u566c\u7ec6\u80de\uff0c\u4e5f\u53ef\u89c1\u7ec6\u80de\u819c\u5411\u5185\u51f9\u9677\u3002\u7ec6\u80de\u819c\u5916\u8868\u9762\u6709\u4e00\u5c42\u8f83\u539a\u7684\u7ec6\u80de\u8863\uff088~16\u03bcm\u539a\uff09\uff0c\u53ef\u88ab\u948c\u7ea2\u7740\u8272\u3002\u7ec6\u80de\u8863\u542b\u9178\u6027\u9ecf\u591a\u7cd6\u3002\u7ec6\u80de\u6838\u5e38\u6709\u51f9\u9677\uff0c\u5375\u5706\u5f62\u6216\u9a6c\u8e44\u94c1\u5f62\uff0c\u5f02\u67d3\u8272\u8d28\u5448\u5c0f\u5757\u72b6\uff0c\u591a\u6cbf\u6838\u819c\u5185\u9762\u5206\u5e03\uff0c\u6838\u5b54\u7279\u522b\u591a\u3002\u7ec6\u80de\u8d28\u4e30\u5bcc\uff0c\u5728\u6838\u7684\u51f9\u9677\u5904\u6709\u4e2d\u5fc3\u4f53\u548c\u8f83\u5927\u7684\u9ad8\u5c14\u57fa\u590d\u5408\u4f53\u3002\u80de\u8d28\u6563\u5728\u4e2d\u7b49\u91cf\u7684\u6e38\u79bb\u6838\u7cd6\u4f53\u548c\u5c11\u91cf\u6ed1\u9762\u5185\u8d28\u7f51\uff0c\u7c97\u9762\u5185\u8d28\u7f51\u6709\u7684\u591a\uff08\u5982\u5927\u3001\u5c0f\u9f20\uff09\uff0c\u6709\u7684\u5c11\uff08\u5982\u4eba\uff09\u3002\u7ebf\u7c92\u4f53\u8f83\u5c11\uff0c\u957f\u5375\u5706\u5f62\uff0c\u591a\u805a\u96c6\u5728\u9ad8\u5c14\u57fa\u590d\u5408\u4f53\u5468\u56f4\uff0c\u901a\u5e38\u4e5f\u6709\u4e00\u4e9b\u5206\u6563\u5728\u7ec6\u80de\u5468\u7f18\u90e8\u3002\u80de\u8d28\u5185\u6709\u5fae\u4e1d\u3001\u5fae\u7ba1\u548c\u4e2d\u95f4\u4e1d\u3002\u5fae\u4e1d\u5bcc\u4e8e\u808c\u52a8\u86cb\u767d\uff0c\u5728\u7ec6\u80de\u819c\u4e0b\u65b9\u6784\u6210\u5fae\u4e1d\u7f51\u3002\u5de8\u566c\u7ec6\u80de\u542b\u5927\u91cf\u6eb6\u9176\u4f53\uff0c\u5e38\u4e0e\u541e\u566c\u4f53\u6216\u541e\u996e\u6ce1\uff0c\u5f62\u6210\u6b21\u7ea7\u6eb6\u9176\u4f53\u79f0\u541e\u566c\u6eb6\u9176\u4f53\uff0c\u6210\u719f\u7684\u548c\u529f\u80fd\u6d3b\u8dc3\u7684\u5de8\u566c\u7ec6\u80de\u76b1\u895e\u548c\u5fae\u7ed2\u6bdb\u66f4\u591a\uff0c\u80de\u8d28\u5185\u7684\u541e\u566c\u4f53\u3001\u6db2\u6ce1\u3001\u6eb6\u9176\u4f53\u548c\u5185\u8d28\u7f51\u66f4\u4e30\u5bcc\u3002<\/p>\n

\u75c5\u7406\u60c5\u51b5\u4e0b\uff0c\u5de8\u566c\u7ec6\u80de\u53ef\u53d8\u4e3a\u4e0a\u76ae\u6837\u7ec6\u80de\u6216\u591a\u6838\u5de8\u7ec6\u80de\u3002\u5728\u7ed3\u6838\u548c\u9ebb\u98ce\u6162\u6027\u708e\u75c7\u7076\u7684\u574f\u6b7b\u7ec4\u7ec7\u5468\u56f4\u5e38\u805a\u96c6\u4e0a\u76ae\u6837\u7ec6\u80de\u548c\u591a\u6838\u5de8\u7ec6\u80de\uff08Langhans\u7ec6\u80de\uff09\u3002\u5de8\u566c\u7ec6\u80de\u805a\u96c6\u5728\u4e00\u8d77\uff0c\u7ec6\u80de\u95f4\u5f62\u6210\u7d27\u5bc6\u8fde\u63a5\uff0c\u5f62\u4f3c\u4e0a\u76ae\uff0c\u79f0\u4e0a\u76ae\u6837\u7ec6\u80de\u3002\u7ec6\u80de\u5448\u591a\u8fb9\u5f62\uff0c\u80de\u8d28\u4e30\u5bcc\uff0c\u55dc\u9178\u6027\uff0c\u6eb6\u9176\u4f53\u51cf\u5c11\uff1b\u6838\u5375\u5706\u5f62\u6216\u5706\u5f62\uff0c\u6ce1\u72b6\uff0c\u8272\u6d45\u3002<\/p>\n

\u7ec4\u7ec7\u5185\u5f02\u7269\uff08\u5982\u7f1d\u7ebf\u3001\u690d\u5165\u6216\u5438\u5165\u7684\u56fa\u4f53\u7269\u8d28\uff0c\u6ce8\u5c04\u7684\u6cb9\u5242\u7b49\uff09\u8f83\u5927\u6216\u96be\u4e8e\u88ab\u541e\u566c\u548c\u8fdb\u884c\u7ec6\u80de\u5185\u6d88\u5316\uff0c\u5728\u5f02\u7269\u5468\u56f4\u5e38\u89c1\u591a\u6838\u5de8\u7ec6\u80de\u6216\u5f02\u7269\u5de8\u7ec6\u80de\u3002\u7ec6\u80de\u5f88\u5927\uff08\u76f4\u5f8440~50\u03bcm\uff09\uff0c\u80de\u8d28\u4e30\u5bcc\uff0c\u6838\u5f88\u591a\uff0c50\u4e2a\u5de6\u53f3\uff0c\u6563\u5728\u4e8e\u7ec6\u80de\u4e2d\u592e\uff1bLanghans\uff08\u6717\u683c\u6c49\u65af\/\u90ce\u7f55\uff09\u7ec6\u80de\u7684\u6838\u5e38\u4f4d\u4e8e\u7ec6\u80de\u5468\u7f18\u90e8\uff0c\u5448\u9a6c\u8e44\u94c1\u5f62\u6392\u5217\u3002<\/p>\n<\/p>\n

\u7334\u5de8\u566c\u7ec6\u80de\uff081Bar=1\u03bcm\uff09<\/p>\n

\u5de8\u566c\u7ec6\u80de\u5206\u6ccc\u7269\uff1a<\/p>\n

\u9176\u7c7b\uff1a<\/p>\n

\u9178\u6027\u6c34\u89e3\u9176\uff08acid hydrolase \uff09\uff1a\u53c2\u4e0e\u7ec6\u80de\u5185\u964d\u89e3<\/p>\n

\u6eb6\u83cc\u9176\uff08Lysozyme\uff09\uff1a\u6d88\u5316\u7ec6\u83cc\u7684\u7ec6\u80de\u58c1<\/p>\n

\u4e2d\u6027\u86cb\u767d\u9176\uff08Neutral protease\uff09\uff1a\u80f6\u539f\u86cb\u767d\u9176\uff08Collagenase\uff09\u3001\u5f39\u6027\u86cb\u767d\u9176\uff08Elastase\uff09\u3001\u8840\u7ea4\u7ef4\u86cb\u767d\u9176\u539f\u6fc0\u6d3b\u7269\u548c\u6eb6\u7ec6\u80de\u86cb\u767d\u9176\u7b49<\/p>\n

\u7cbe\u6c28\u9178\u9176\uff08arginase\uff09\uff1a\u5206\u89e3\u7ec6\u80de\u65b0\u9648\u4ee3\u8c22\u5fc5\u9700\u7684\u7cbe\u6c28\u9178\uff0c\u6291\u5236\u7ec6\u80de\u529f\u80fd\uff0c\u6291\u5236\u80bf\u7624\u7ec6\u80de\u589e\u6b96<\/p>\n

\u82b1\u751f\u56db\u70ef\u9178\u884d\u751f\u7269\u53ca\u5176\u4ed6\u8102\u8d28\u4ecb\u8d28\uff1a<\/p>\n

PGE2<\/sub>\uff0c\u767d\u7ec6\u80de\u4e09\u70efC\uff08LTC\uff09\uff0c\u8840\u5c0f\u677f\u6d3b\u5316\u56e0\u5b50\uff08Platelet-activating factor,PAF\uff09\uff0c\u5177\u6709\u708e\u75c7\u4ecb\u8d28\u4f5c\u7528\uff0c\u5f71\u54cd\u7c92\u7ec6\u80de\u3001\u8840\u5c0f\u677f\u3001\u5185\u76ae\u7ec6\u80de\u548c\u5e73\u6ed1\u808c\u7ec6\u80de\u529f\u80fd<\/p>\n

\u8c03\u8282\u7ec6\u80de\u6d3b\u52a8\u548c\u589e\u6b96\u7684\u7269\u8d28\uff1a\u5e72\u6270\u7d20\uff08IFN\uff09\u548cIL\uff0c\u7c92\u7cfb\u5de8\u566c\u7cfb\u4ed8\u8bf8\u4e1c\u6d41\u523a\u6fc0\u56e0\u5b50\uff08GM-CSF\uff09\u3001\u7ea2\u7ec6\u80de\u751f\u6210\u7d20\u3001FGF\u3001\u5185\u76ae\u7ec6\u80de\u751f\u957f\u56e0\u5b50\u3001\u80bf\u7624\u574f\u6b7b\u56e0\u5b50\uff08TNF\uff09\u3001\u8840\u7ba1\u751f\u6210\u56e0\u5b50\u3001\u8d8b\u5316\u56e0\u5b50\uff08\u5982\u591a\u5f62\u6838\u767d\u7ec6\u80de\u8d8b\u5316\u56e0\u5b50\uff09\u3001\u4fc3\u6dcb\u5df4\u7ec6\u80de\u548c\u4fc3\u6210\u7ea4\u7ef4\u7ec6\u80de\u589e\u6b96\u56e0\u5b50\u3001\u8c03\u8282\u5176\u4ed6\u7ec6\u80de\u4ee3\u8c22\u7684\u56e0\u5b50\uff08\u5982\u809d\u7ec6\u80de\u6dc0\u7c89\u6837\u86cb\u767dP\u6210\u5206\u7b49\uff09\uff0c\u6fc0\u6d3b\u548c\u8c03\u8282\u76f8\u5173\u7ec6\u80de\u7684\u6d3b\u52a8<\/p>\n

\u5176\u4ed6\u5206\u6ccc\u7269\uff1a<\/p>\n

\u8865\u4f53\u7cfb\u7edfC1<\/sub>\uff0cC2<\/sub>\uff0cC3<\/sub>\uff0cC4<\/sub>\uff0cC5<\/sub>\uff0c\u56e0\u5b50B\u3001D\u7b49\uff0c\u6eb6\u89e3\u67d0\u4e9b\u7ec6\u83cc\u548c\u7ec6\u80de\uff08\u5982\u7ea2\u7ec6\u80de\uff09\uff0c\u4e5f\u6709\u8d8b\u5316\u4f5c\u7528<\/p>\n

\u6c27\u5316\u4ee3\u8c22\u4ea7\u7269H2<\/sub>O2<\/sub>\u3001O2<\/sub>-\u3001OH–<\/sup>\u3001IO2<\/sub>\u7b49\u5f3a\u6c27\u5316\u5242\uff0c\u6709\u7ec6\u80de\u6bd2\u4f5c\u7528\u5728\u5de8\u566c\u7ec6\u80de\u6740\u83cc\u548c\u6740\u80bf\u7624\u7ec6\u80de\u4e2d\u8d77\u91cd\u8981\u4f5c\u7528<\/p>\n

\u5176\u4ed6\u51dd\u8840\u56e0\u5b50\u5982\u2164\u3001\u2166\u3001\u2168\u3001\u2169\u7b49<\/p>\n

\u535f\u5549\u548c\u5627\u5576\u4ea7\u7269\u5982\u80f8\u82f7\uff08Thymidine\uff09\u3001\u5c3f\u9178\uff08Uric acid\uff09\u3001\u5c3f\u5627\u5576 (Uracil) \u7b49<\/p>\n

\u7ed3\u5408\u86cb\u767d\u5982FN\uff08 fibronectin\u7ea4\u7ef4\u8fde\u63a5\u86cb\u767d\uff09<\/p>\n

\u5be1\u80bd\u5982\u8c37\u80f1\u7518\u80bd\uff08glutathione\uff0cGSH\uff09<\/p>\n

\u5176\u4ed6\u6fc0\u7d20\u6837\u7269\u8d28\u5982\u5185\u6e90\u6027\u81f4\u70ed\u539f\uff08endogenous pyrogen\uff09\u6216\u767d\u7ec6\u80de\u81f4\u70ed\u539f\uff08\u5982IL-2\uff0cTNF\uff0c\u5e72\u6270\u7d20IFN\uff09<\/p>\n

3 \u6d46\u7ec6\u80de\uff08plasma cell)<\/p>\n

\u758f\u677e\u7ed3\u7f14\u7ec4\u7ec7\u5f88\u5c11\u89c1\uff0c\u5728\u75c5\u539f\u83cc\u6216\u5f02\u6027\u86cb\u767d\u8d28\u6613\u4e8e\u4fb5\u5165\u7684\u90e8\u4f4d\uff0c\u5982\u6d88\u5316\u7ba1\u548c\u547c\u5438\u9053\u56fa\u6709\u5c42\u7ed3\u7f14\u7ec4\u7ec7\u5185\u5e38\u89c1\u6d46\u7ec6\u80de<\/p>\n<\/p>\n

\u4eba\u9f3b\u606f\u8089\u5185\u7684\u6d46\u7ec6\u80de\uff08\u2196\uff09<\/p>\n

\u4e3b\u8981\u5206\u5e03\u5728\u813e\u3001\u6dcb\u5df4\u7ed3\u53ca\u6d88\u5316\u7ba1\u3001\u547c\u5438\u9053\u56fa\u6709\u5c42\u7ed3\u7f14\u7ec4\u7ec7\u6216\u6dcb\u5df4\u7ec4\u7ec7\u5185<\/p>\n

\u75c5\u7406\u60c5\u51b5\u4e0b\uff0c\u5982\u6162\u6027\u708e\u75c7\u75c5\u7076\u6216\u8089\u82bd\u80bf\u5185\uff0c\u6d46\u7ec6\u80de\u589e\u591a<\/p>\n

\u6d46\u7ec6\u80de\u4e5f\u89c1\u4e8e\u4f53\u5185\u5404\u5904\u7684\u6dcb\u5df4\u7ec4\u7ec7\u5185<\/p>\n

\u5f62\u6001\u7ed3\u6784\uff1a<\/p>\n

\u6d46\u7ec6\u80de\u5375\u5706\u5f62\u6216\u5706\u5f62\uff0c\u96c6\u805a\u4e00\u8d77\u4e3a\u591a\u8fb9\u5f62\u3002\u76f4\u5f848~20\u339b\u3002\u6210\u719f\u7684\u6d46\u7ec6\u80de\u6709\u4e00\u4e2a\u5706\u5f62\u6838\u5e38\u504f\u4e8e\u7ec6\u80de\u4e00\u4fa7\uff0c\u6838\u5185\u65e0\u660e\u663e\u6838\u4ec1\uff0c\u5f02\u67d3\u8272\u8d28\u591a\uff0c\u6838\u7740\u8272\u6df1\uff1b\u7c97\u5927\u7684\u5f02\u67d3\u8272\u8d28\u5757\u591a\u6cbf\u6838\u819c\u5185\u9762\u5448\u8f90\u5c04\u72b6\u6392\u5217\uff0c\u5f62\u4f3c\u8f66\u8f6e\u72b6\uff08\u8f66\u8f6e\u72b6\u6838\uff09\u3002\u7ec6\u80de\u8d28\u4e30\u5bcc\uff0c\u55dc\u78b1\u6027\uff0c\u6838\u4e00\u4fa7\u8fd1\u7ec6\u80de\u4e2d\u592e\u5904\u6709\u4e00\u6d45\u67d3\u533a\u3002<\/p>\n

\u7535\u955c\u4e0b\uff0c\u6d46\u7ec6\u80de\u8868\u9762\u5149\u6ed1\uff0c\u4ec5\u6709\u5f88\u5c11\u5fae\u7ed2\u6bdb\u72b6\u7a81\u8d77\u3002\u6210\u719f\u7684\u6d46\u7ec6\u80de\u80de\u8d28\u5185\u5145\u6ee1\u7c97\u9762\u5185\u8d28\u7f51\u548c\u5927\u91cf\u6e38\u79bb\u591a\u6838\u7cd6\u4f53\uff0c\u7c97\u9762\u5185\u8d28\u7f51\u5448\u6241\u56ca\u72b6\uff0c\u5bc6\u96c6\u6392\u5217\u6210\u540c\u5fc3\u5c42\u3002\u4e00\u4e9b\u6d46\u7ec6\u80de\uff0c\u5c24\u5176\u5408\u6210\u6297\u4f53\u6d3b\u8dc3\u7684\u6d46\u7ec6\u80de\uff0c\u90e8\u5206\u5185\u8d28\u7f51\u8154\u6269\u5927\u6210\u5c0f\u6ce1\u72b6\uff0c\u8154\u5185\u6709\u7535\u5b50\u5bc6\u5ea6\u4f4e\u7684\u7d6e\u72b6\u7269\u8d28\u3002\u6838\u65c1\u6d45\u67d3\u533a\u6709\u53d1\u8fbe\u7684\u9ad8\u5c14\u57fa\u590d\u5408\u4f53\u3001\u4e2d\u5fc3\u707e\u548c\u4e00\u4e9b\u5206\u6ccc\u5c0f\u6ce1\u3001\u4e00\u4e9b\u5706\u5f62\u7ebf\u7c92\u4f53\u5206\u6563\u5728\u7ec6\u80de\u8d28\u5185<\/p>\n<\/p>\n

\u6709\u4e9b\u6d46\u7ec6\u80de\u80de\u8d28\u5185\u51fa\u73b0\u5747\u8d28\u7684\u7403\u5f62\u55dc\u9178\u6027\u5c0f\u4f53\uff0c\u4f0a\u7ea2\u67d3\u6210\u6df1\u7ea2\u8272\uff0c\u79f0Russel\uff08\u62c9\u585e\u5c14\uff09\u5c0f\u4f53\u3002\u6162\u6027\u708e\u75c7\u7684\u80c3\u9ecf\u819c\u548c\u9f3b\u9ecf\u819c\u5185\u53ef\u89c1\u7ea2\u8272\u5c0f\u4f53\u3002\u7ec4\u5316\u6cd5\ud84c\uddfc\u5c0f\u4f53\u542b\u7cd6\u86cb\u767d\uff1b\u514d\u75ab\u8367\u5149\u8bc1\u5b9e\u4e3a\u514d\u75ab\u7403\u86cb\u767d\u3002<\/p>\n

Russel\u5c0f\u4f53\u5b58\u5728\u4e8e\u6269\u5927\u7684\u7c97\u9762\u5185\u8d28\u7f51\u8154\u5185\u6216\u7ec6\u80de\u6838\u5185\u3002\u5728\u5e7d\u95e8\u87ba\u65cb\u6746\u83cc\u611f\u67d3\u7684\u80c3\u9ecf\u819c\u6d3b\u68c0\u7ec4\u7ec7\u4e2d\u6709\u805a\u96c6\u6210\u7fa4\u7684\u542bRussel\u5c0f\u4f53\u7684\u6d46\u7ec6\u80de\u3002\u5145\u6ee1Russel\u5c0f\u4f53\u7684\u6d46\u7ec6\u80de\u5448\u8868\u9762\u6297\u539f\u5206\u5316\u7c07\uff08CD\uff0945\uff08CD45\uff09\u3001CD79\u548c IgG\u53cd\u5e94\u9633\u6027<\/p>\n<\/p>\n

\u5154\u4e0b\u988c\u4e0b\u817a\u6d46\u7ec6\u80de\uff08Bar=1\u339b\uff09<\/p>\n

B\u7ec6\u80de\u751f\u957f\u56e0\u5b50\uff08BCGF\uff09\u53d7\u4f53\uff0cMHGC\u2161\u7c7b\u6297\u539f\uff0c\u8f85\u52a9\u6027T\u7ec6\u80de\u4ea7\u751fBCGF<\/p>\n

\u4f11\u6b62B\u7ec6\u80de\u6fc0\u6d3b\u7684\u56e0\u5b50\uff1a\u6297\u539f\u3001\u6297\u6297\u4f53\u3001IL-4\uff08BSF-1\u3001BCGF-1\uff09\u3001IL-5\u7b49\uff1b<\/p>\n

\u5f15\u8d77\u6d3b\u5316B\u7ec6\u80de\u751f\u957f\u548c\u589e\u6b96\u7684\u56e0\u5b50\uff1aIL-2\uff0cI\u80c3\u80a0\u9053\u9ecf\u6db2\u764c\uff0cIL-5\uff08\u5c0f\u9f20IL-5\u79f0BCGF-2\uff09\uff0cIL-6\uff08\u4eba\u7684IL-6\u79f0BSF-2\u3001BCGF-1\uff09\uff0cIL-7\uff08\u53ea\u4f5c\u7528\u4e8e\u524dB\u7ec6\u80de\uff09\uff0cC3<\/sub>\u7b49\uff1b<\/p>\n

\u8bf1\u5bfcB\u7ec6\u80de\u5206\u5316\u7684\u56e0\u5b50\uff1a\u5982IL-2\uff0cIL-5\uff08\u5c0f\u9f20\uff09\uff0cIL-6\uff08\u4eba\uff09<\/p>\n

\u4f11\u6b62\u7684B\u6dcb\u5df4\u7ec6\u80de\u6d3b\u5316\u4e3a\u4f53\u79ef\u5927\u7684\u514d\u75ab\u6bcd\u7ec6\u80de\u5373\u539f\u6d46\u7ec6\u80de\uff0c\u80de\u8d28\u80fd\u88ab\u6d3e\u82e5\u5b81\uff08pyronin\uff09\u67d3\u6210\u7ea2\u8272\uff0c\u53c8\u79f0\u55dc\u6d3e\u82e5\u5b81\u7ec6\u80de\u3002\u539f\u6d46\u7ec6\u80de\u76f4\u5f8415~25\u339b\uff0c\u6838\u5706\u5f62\u6216\u5375\u5706\u5f62\uff0c\u504f\u5fc3\u4f4d\uff0c\u5e38\u67d3\u8272\u8d28\u591a\uff0c\u67092~4\u4e2a\u8f83\u5927\u7684\u6838\u4ec1\uff1b\u7ec6\u80de\u8d28\u591a\uff0c\u5f3a\u55dc\u78b1\u6027\u3002\u7535\u955c\u4e0b\uff0c\u6e38\u79bb\u6838\u7cd6\u4f53\u5f88\u591a\uff0c\u6709\u4e00\u4e9b\u7c97\u9762\u5185\u8d28\u7f51\uff0c\u6838\u5468\u9699\u548c\u7c97\u9762\u5185\u8d28\u7f51\u8154\u5185\u5148\u540e\u51fa\u73b0\u6297\u4f53\u3002\u5206\u5316\u4e3a\u5e7c\u6d46\u7ec6\u80de<\/p>\n

\u5e7c\u6d46\u7ec6\u80de\uff1a\u76f4\u5f8415~25\u339b\uff0c\u6838\u5706\u5f62\u6216\u5375\u5706\u5f62\uff0c\u504f\u5fc3\u4f4d\uff0c\u67d3\u8272\u8d28\u9897\u7c92\u4e2d\u7b49\u5927\u5c0f\uff0c\u67091~2\u4e2a\u8f83\u5c0f\u6838\u4ec1\uff0c\u80de\u8d28\u5185\u5e38\u89c1\u6838\u65c1\u6d45\u67d3\u533a\u3002\u7535\u955c\u4e0b\uff0c\u9ad8\u5c14\u57fa\u590d\u5408\u4f53\u53d1\u80b2\u826f\u597d\uff0c\u7c97\u9762\u5185\u8d28\u7f51\u66f4\u53d1\u8fbe\uff0c\u5448\u540c\u5fc3\u5706\u5e73\u884c\u6392\u5217\uff0c\u6709\u4e9b\u5185\u8d28\u7f51\u56ca\u8154\u5448\u6ce1\u72b6\u6269\u5927\uff0c\u4f46\u6838\u5468\u9699\u5185\u6297\u4f53\u6d88\u5931\u3002\u5206\u5316\u4e3a\u6210\u719f\u6d46\u7ec6\u80de<\/p>\n

4 \u80a5\u5927\u7ec6\u80de\uff08mast cell)<\/p>\n

\u5e38\u6cbf\u5c0f\u8840\u7ba1\u548c\u5c0f\u6dcb\u5df4\u7ba1\u5206\u5e03\uff0c\u4e5f\u89c1\u4e8e\u67d0\u4e9b\u5668\u5b98\u7684\u88ab\u819c\uff08\u5305\u62ec\u8111\u819c\uff09\u548c\u8109\u7edc\u4e1b\u5185\u53ca\u5468\u56f4\u795e\u7ecf\u7684\u795e\u7ecf\u5916\u819c\u548c\u795e\u7ecf\u675f\u819c\u5185\u3002\u5728\u8eab\u4f53\u63a5\u89e6\u5916\u754c\u7684\u5730\u65b9\uff0c\u5982\u76ae\u80a4\u3001\u547c\u5438\u9053\u548c\u6d88\u5316\u9053\u4e0a\u76ae\u4e0b\u65b9\u7684\u7ed3\u7f14\u7ec4\u7ec7\u5185\uff0c\u80a5\u5927\u7ec6\u80de\u7279\u522b\u591a\u3002\u6b63\u5e38\u4eba\u7684\u76ae\u80a4\u67097000~12000\u4e2a\/mm3<\/sup>\u3002<\/p>\n<\/p>\n

\u7532\u82ef\u80fa\u84dd\u67d3\u8272\u793a\u80a5\u5927\u7ec6\u80de<\/p>\n

\u80a5\u5927\u7ec6\u80de\u6570\u91cf\u4e0e\u52a8\u7269\u79cd\u5c5e\u548c\u5668\u5b98\u6709\u5173\uff1a<\/p>\n

\u8c5a\u9f20\u548c\u5bb6\u5154\u7684\u758f\u677e\u7ed3\u7f14\u7ec4\u7ec7\u5185\u80a5\u5927\u7ec6\u80de\u8f83\u5c11\uff1b<\/p>\n

\u72ac\u3001\u732b\u3001\u733f\u548c\u4eba\u7684\u758f\u677e\u7ed3\u7f14\u7ec4\u7ec7\u5185\u8f83\u591a\uff1b<\/p>\n

\u5927\u9f20\u548c\u5c0f\u529b\u758f\u677e\u7ed3\u7f14\u7ec4\u7ec7\u5185\u66f4\u591a\u3002<\/p>\n

\u5b9e\u8d28\u6027\u5668\u5b98\u5982\u809d\u3001\u80be\u548c\u80be\u4e0a\u817a\u5185\u7684\u7ed3\u7f14\u7ec4\u7ec7\u5185\u80a5\u5927\u7ec6\u80de\u8f83\u5c11\uff1b<\/p>\n

\u72ac\u809d\u5185\u6709\u8f83\u591a\u7684\u80a5\u5927\u7ec6\u80de\u3002<\/p>\n

\u7ed3\u7f14\u7ec4\u7ec7\u8f83\u591a\u7684\u5668\u5b98\u5982\u4e73\u817a\u3001\u820c\u3001\u524d\u5217\u817a\u3001\u80ba\u548c\u7f51\u819c\u5185\uff0c\u80a5\u5927\u7ec6\u80de\u8f83\u591a<\/p>\n

\u6b63\u5e38\u9aa8\u9ad3\u548c\u6dcb\u5df4\u7ec4\u7ec7\u5185\uff0c\u80a5\u5927\u7ec6\u80de\u4e0d\u591a\uff1b<\/p>\n

\u6b63\u5e38\u5faa\u73af\u8840\u6db2\u5185\u6ca1\u6709\u6210\u719f\u7684\u80a5\u5927\u7ec6\u80de<\/p>\n

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\u5f62\u6001\u7ed3\u6784\uff1a<\/p>\n

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\u5168\u8eab\u6027\u80a5\u5927\u7ec6\u80de\u589e\u591a\u75c7\uff1a\u9aa8\u9ad3\u3001\u813e\u3001\u6dcb\u5df4\u7ed3\u548c\u809d\u5185\u7ea4\u7ef4\u589e\u751f\uff0c\u4e0e\u80a5\u5927\u7ec6\u80de\u589e\u591a\u6709\u5173<\/p>\n

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\u5728\u795e\u7ecf\u7f51\u7edc\u81f4\u5bc6\u7684\u7ec4\u7ec7\u5982\u5c0f\u80a0\u548c\u53f3\u5fc3\u623f\u5185\uff0c\u5f88\u591a\u80a5\u5927\u7ec6\u80de\u5206\u5e03\u5728\u8fd1\u8f74\u7d22100nm\u5185\uff1b\u5728\u795e\u7ecf\u7f51\u7edc\u7a00\u758f\u7684\u7ec4\u7ec7\u5982\u80ba\u5b9e\u8d28\u548c\u8033\u76ae\u80a4\u4e2d\uff0c\u5728\u8f74\u7d22\u8fd1100nm\u5185\uff0c\u51e0\u4e4e\u65e0\u80a5\u5927\u7ec6\u80de<\/p>\n

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\u4ec5\u542b\u7c7b\u80f0\u86cb\u767d\u9176\uff08T\u9176\uff09\u7684\u80a5\u5927\u7ec6\u80de\uff08MCT\uff09\uff0c\u65e2\u542bT\u9176\u53c8\u542b\u80c3\u4fc3\u80f0\u9176\uff08C\u9176\uff09\u8c8c\u80a5\u5927\u7ec6\u80de\uff08MCTC\uff09<\/p>\n

MCTC\u8fd8\u542b\u7ec4\u7ec7\u86cb\u767d\u9176G\u548c\u7fa7\u80bd\u9176<\/p>\n

MCT\u4e3b\u8981\u5b58\u5728\u4e8e\u53d8\u6001\u53cd\u5e94\u6027\u75be\u75c5\u60a3\u8005\u7684\u5c0f\u80a0\u9ecf\u819c\u3001\u80ba\u6ce1\u548c\u80ba\u5bfc\u6c14\u90e8\u4e0a\u76ae\u5185\uff1bMCTC\u4e3b\u8981\u5b58\u5728\u4e8e\u80a0\u9ecf\u819c\u4e0b\u5c42\u3001\u5b50\u5bab\u5185\u819c\u3001\u76ae\u80a4\u548c\u547c\u5438\u9053\u4e0a\u76ae\u4e0b\u7ed3\u7f14\u7ec4\u7ec7\u5185<\/p>\n

\u4eba\u7684\u9f7f\u9f88\u7ed3\u7f14\u7ec4\u7ec7\u542bMCT\u548cMCTC\uff0c\u4ee5MCT\u4e3a\u4e3b<\/p>\n

5 \u8102\u80aa\u7ec6\u80de<\/p>\n

\u5355\u6ce1\u8102\u80aa\u7ec6\u80de\uff08\u8102\u80aa\u7ec6\u80de\uff09\uff1a\u5e38\u6cbf\u8840\u7ba1\u5206\u5e03\uff0c\u5355\u4e2a\u6216\u6210\u7fa4\u5b58\u5728\uff0c\u82e5\u5927\u91cf\u805a\u96c6\uff0c\u53ef\u5f62\u6210\u8bb8\u591a\u5c0f\u53f6\uff0c\u6784\u6210\u8102\u80aa\u7ec4\u7ec7\u3002\u8102\u80aa\u7ec6\u80de\u4f53\u79ef\u5927\uff0c\u76f4\u5f84100~200\u339b\uff0c\u5448\u5706\u7403\u5f62\uff0c\u76f8\u4e92\u6324\u538b\u5219\u5448\u591a\u8fb9\u5f62\u3002\u80de\u8d28\u5185\u6709\u4e00\u4e2a\u5927\u7684\u8102\u6ef4\uff0c\u5360\u636e\u7ec6\u80de\u8d28\u5927\u90e8\uff0c\u5c06\u5c06\u7ec6\u80de\u8d28\u7684\u5176\u4f59\u90e8\u5206\u63a8\u6324\u5230\u7ec6\u80de\u7684\u5468\u7f18\uff0c\u6210\u4e3a\u5f88\u8584\u7684\u4e00\u5c42\uff0c\u5305\u56f4\u8102\u6ef4\uff0c\u4ec5\u5728\u7ec6\u80de\u6838\u9644\u8fd1\u7684\u7ec6\u80de\u8d28\u7565\u591a\u3002HE\u5207\u7247\u4e0a\uff0c\u8102\u80aa\u7ec6\u80de\u7684\u8102\u6ef4\u88ab\u6eb6\u89e3\uff0c\u53ea\u7559\u4e0b\u5468\u7f18\u5f88\u8584\u7684\u7ec6\u80de\u8d28\uff0c\u7ec6\u80de\u50cf\u4e00\u4e2a\u5927\u7a7a\u6ce1\u3002\u51b0\u51bb\u5207\u7247\u9507\u9178\u67d3\u8272\uff0c\u5728\u8102\u6ef4\u5185\u5f62\u6210\u9ed1\u8272\u7684\u9507\u9178\u916f\u3002\u7528\u82cf\u4e39\u67d3\u8272\uff0c\u8102\u6ef4\u5448\u9ed1\u8272\u6216\u7ea2\u8272\u3002\u53ef\u7528\u7ec4\u5316\u663e\u793a\u5176\u78b1\u6027\u78f7\u9178\u9176\u3001\u916f\u9176\u3001\u7425\u73c0\u9178\u8131\u6c22\u9176\u548c\u5c11\u91cf\u6c27\u5316\u9176\u3002<\/p>\n

\u7535\u955c\u4e0b\uff0c\u8102\u80aa\u7ec6\u80de\u8584\u5c42\u80de\u8d28\u5185\u53ef\u89c1\u6e38\u79bb\u6838\u7cd6\u4f53\uff0c\u5c11\u91cf\u7c97\u9762\u5185\u8d28\u7f51\u548c\u7ebf\u7c92\u4f53\uff0c\u65e0\u819c\u5305\u7684\u8102\u6ef4\uff0c\u6838\u9644\u8fd1\u6709\u5c0f\u7684\u9ad8\u5c14\u57fa\u590d\u5408\u4f53\u3002\u6bcf\u4e2a\u8102\u80aa\u7ec6\u80de\u52a0\u8fbe\u9ed8\u5c14\u663c\u57fa\u677f\u548c\u5fae\u7ec6\u7684\u7f51\u72b6\u7ea4\u7ef4\u7f51<\/p>\n

\u591a\u6ce1\u8102\u80aa\u7ec6\u80de\uff1a\u7565<\/p>\n

6 \u672a\u5206\u5316\u95f4\u5145\u8d28\u7ec6\u80de'<\/p>\n

\u5e38\u5206\u5e03\u5728\u5c0f\u8840\u7ba1\u5468\u56f4\uff0c\u5c24\u5176\u662f\u6bdb\u7ec6\u8840\u7ba1\u5468\u56f4\u3002\u2019<\/p>\n

\u7ec6\u80de\u5c0f\uff0c\u661f\u5f62\u6216\u68ad\u5f62\uff0c\u4e0e\u6210\u7ea4\u7ef4\u7ec6\u80de\u76f8\u4f3c\u3002\u5207\u7247\u4e0a\u4e0d\u6613\u4e0e\u6210\u7ea4\u7ef4\u7ec6\u80de\u533a\u522b <\/p>\n

\u7535\u955c\u4e0b\uff0c\u542b\u8f83\u5c11\u7684\u7ebf\u7c92\u4f53\u548c\u5f88\u5c11\u7684\u5185\u8d28\u7f51<\/p>\n

\u53ef\u5206\u5316\u4e3a\u7ed3\u7f14\u7ec4\u7ec7\u7ec6\u80de\uff08\u6210\u7ea4\u7ef4\u7ec6\u80de\u3001\u8102\u80aa\u7ec6\u80de\u7b49\uff09\uff1b\u65b0\u751f\u8840\u7ba1\u7684\u5185\u76ae\u7ec6\u80de\u548c\u5e73\u6ed1\u808c\u7ec6\u80de<\/p>\n

7 \u767d\u7ec6\u80de<\/p>\n

\u5355\u6838\u7ec6\u80de\uff0c\u55dc\u9178\u6027\u7c92\u7ec6\u80de\uff0c\u6dcb\u5df4\u7ec6\u80de\uff0c\u4e2d\u6027\u7c92\u7ec6\u80de<\/p>\n

\u55dc\u9178\u6027\u7c92\u7ec6\u80de\u6838\u5206\u53f6\uff08\u5e38\u4e3a2\u53f6\uff09\uff0c\u7ec6\u80de\u819c\u4e0a\u6709\u8868\u9762Fc\u53d7\u4f53\u548cC3\u53d7\u4f53\u3002\u80de\u8d28\u5185\u5145\u6ee1\u55dc\u9178\u9897\u7c92\uff0c\u4f0a\u7ea2\u67d3\u6210\u6a58\u7ea2\u8272\u3002\u9897\u7c92\u542b\u591a\u79cd\u6c34\u89e3\u9176\u3002\u4e0e\u8d85\u654f\u53cd\u5e94\u5e94\u7b54\u6709\u5173\uff1b\u91ca\u653e\u55dc\u9178\u6027\u7c92\u7ec6\u80de\u9633\u79bb\u5b50\u86cb\u767d\uff08ECO\uff09\uff0c\u6740\u706d\u5bc4\u751f\u866b\u3002 <\/p>\n

\u7ec6\u80de\u95f4\u8d28\uff08\u7ec6\u80de\u5916\u57fa\u8d28ECM\uff09<\/p>\n

\u7ea4\u7ef4\uff1a\u80f6\u539f\u7ea4\u7ef4\u3001\u5f39\u6027\u7ea4\u7ef4\u3001\u7f51\u72b6\u7ea4\u7ef4<\/p>\n

\u57fa\u8d28\uff1a<\/p>\n

\u7ec4\u7ec7\u6db2<\/p>\n

8 \u80f6\u539f\u7ea4\u7ef4\uff08collagenous fiber\uff09<\/p>\n

\u96c6\u5408\u6210\u675f\uff08\u80f6\u539f\u7ea4\u7ef4\u675f\uff09<\/p>\n

\u65b0\u9c9c\u65f6\u5448\u767d\u8272\uff08\u767d\u7ea4\u7ef4\uff09\uff0c\u6709\u5149\u6cfd\u3002\u8089\u773c\u6240\u89c1\u7684\u8171\u548c\u8171\u819c\u4e3b\u8981\u7531\u5927\u91cf\u80f6\u539f\u7ea4\u7ef4\u7ec4\u6210<\/p>\n

\u5149\u955c\u4e0b\uff0c\u80f6\u539f\u7ea4\u7ef4\u5448\u6ce2\u6d6a\u72b6\uff0c\u65b9\u5411\u4e0d\u5b9a\uff0c\u7c97\u7ec6\u4e0d\u4e00\uff0c\u957f\u77ed\u4e0d\u7b49\uff0c\u5206\u652f\uff0c\u4ea4\u7ec7\u6210\u7f51<\/p>\n

\u76f4\u5f841~20\u339b\uff0c\u7531\u8bb8\u591a\u76f4\u5f8420~200nm\u7684\u80f6\u539f\u539f\u7ea4\u7ef4\u501f\u5c11\u91cf\u9ecf\u5408\u8d28\u800c\u6210<\/p>\n

\u7528\u77f3\u7070\u6c34\u6216\u82e6\u5473\u9178\u6c34\u6eb6\u6db2\u9664\u53bb\u9ecf\u5408\u8d28\uff0c\u53ef\u5206\u79bb\u80f6\u539f\u7ea4\u7ef4<\/p>\n

\u9ecf\u5408\u8d28\u4e3a\u86cb\u767d\u591a\u7cd6\u548c\u7cd6\u86cb\u767d<\/p>\n

\u80f6\u539f\u7ea4\u7ef4\u5448PAS\u53cd\u5e94\u9633\u6027<\/p>\n

\u80f6\u539f\u7ea4\u7ef4\u55dc\u9178\u6027\uff0c\u4f0a\u7ea2\u6216\u9178\u6027\u54c1\u7ea2\u67d3\u8272\uff08Van Gieson\u67d3\u8272\uff09\u6210\u7ea2\u8272\uff1bMallory\u4e09\u8272\u67d3\u8272\u6cd5\u4e3a\u84dd\u8272\uff1bMasson\u4e09\u8272\u67d3\u8272\u6cd5\u4e3a\u7eff\u8272<\/p>\n

\u504f\u5149\u955c\u4e0b\uff0c\u80f6\u539f\u7ea4\u7ef4\u6709\u6b63\u7684\u5355\u8f74\u53cc\u6298\u5149\u6027\uff0c\u82e6\u5473\u9178-Sirius\u7ea2\u67d3\u8272\u5448\u4eae\u7ea2\u8272\uff0c\u7ec6\u957f\u7684\u67d3\u8272\u5206\u5b50\u5e73\u884c\u6392\u5217\uff0c\u53ef\u9274\u522b\u2160\u578b\u548c\u2161\u578b\u80f6\u539f<\/p>\n

\u80f6\u539f\u7ea4\u7ef4\u7531\u80f6\u539f\u86cb\u767d\u7ec4\u6210\uff0c\u6613\u88ab\u80c3\u86cb\u767d\u9176\u6d88\u5316\uff0c\u6d41\u6d6a\u8005\u716e\u6eb6\u89e3\uff0c\u51b7\u51bb\u540e\u540e\u51dd\u80f6\uff08\u660e\u80f6\uff09'\u80f6\u539f\u7ea4\u7ef4\u6613\u6eb6\u4e8e\u7a00\u78b1\u6eb6\u6db2\u5982\u7a00\u6c22\u6c27\u5316\u94be\u6eb6\u6db2\uff0c\u6216\u8f83\u5f3a\u7684\u9178\u6eb6\u6db2\u5982\u51b0\u918b\u9178\u6eb6\u6db2\u3002\u5728\u7a00\u9178\u6eb6\u6db2\u4e2d\uff0c\u80f6\u539f\u7ea4\u7ef4\u4ea7\u751f\u53ef\u9006\u6027`\u81a8\u80c0\uff0c\u65b0\u9c9c\u7ed3\u7f14\u7ec4\u7ec7\u94fa\u7247\u4e2d\u52a0\u7a00\u76d0\u9178\uff0c\u80f6\u539f\u7ea4\u7ef4\u7684\u7eb5\u7eb9\u6d88\u5931\uff0c\u53ef\u89c1\u73af\u5f62\u7f29\u7a84\uff08\u73af\u5f62\u7f51\u72b6\u7ea4\u7ef4\uff09\u3002\u7528\u542b\u7a00\u9178\u7684\u56fa\u5b9a\u6db2\u5904\u7406\u8fc7\u7684\u7ec4\u7ec7\u4e0d\u5b9c\u76f4\u63a5\u6c34\u6d17\uff0c\u5b9c\u7528\u9152\u7cbe\u6216\u7528\u80fd\u9632\u6b62\u80f6\u539f\u7ea4\u7ef4\u81a8\u80c0\u7684\u786b\u9178\u94a0\u6216\u786b\u9178\u9502\u6d78\u6d17<\/p>\n

\u8d85\u5fae\u7ed3\u6784\uff1a\u80f6\u539f\u539f\u7ea4\u7ef4\u53ca\u5176\u95f4\u7684\u5fae\u91cf\u9ecf\u5408\u8d28<\/p>\n

\u80f6\u539f\u539f\u7ea4\u7ef4\u670967nm\u5468\u671f\u6027\u6a2a\u7eb9\uff0c\u5176\u4e3b\u8981\u6210\u5206\u4e3a\u80f6\u539f\u86cb\u767d\u5206\u5b50\uff08\u80f6\u539f\uff09<\/p>\n<\/p>\n

\u80f6\u539f\u7ea4\u7ef4<\/p>\n

A  \u7eb5\u65ad\u9762   Bar=250nm B \u5206\u79bb\u7684\u80f6\u539f\u539f\u7ea4\u7ef4 Bar=1000nm<\/p>\n<\/p>\n

\u6a2a\u65ad\u9762\uff1a\u2605\u80f6\u539f\u539f\u7ea4\u7ef4\u6a2a\u65ad\u9762\u2192\u6210\u7ea4\u7ef4\u7ec6\u80de\u90e8\u5206\u80de\u8d28\u25b2\u5f39\u6027\u7ea4\u7ef4 Bar-250nm<\/p>\n

\u80f6\u539f\u86cb\u767d\uff08collagen\uff09\u7b80\u79f0\u80f6\u539f\uff0c\u662f\u4eba\u4f53\u5185\u542b\u91cf\u6700\u4e30\u5bcc\u7684\u86cb\u767d\u8d28\uff0c\u7ea6\u5360\u4eba\u4f53\u86cb\u767d\u8d28\u603b\u91cf\u2153\uff0c\u5e7f\u6cdb\u5b58\u5728\u4e8e\u5404\u79cd\u7ec4\u7ec7\u548c\u5668\u5b98\u7684\u7ec6\u80de\u5916\u57fa\u8d28\u5185\uff0c\u5982\u76ae\u80a4\u3001\u9aa8\u3001\u8f6f\u9aa8\u8171\u7b49\u7ec4\u7ec7\u5185\u5c24\u4e3a\u4e30\u5bcc\u3002<\/p>\n<\/p>\n

\u80f6\u539f\u6027\u75be\u75c5\uff1a<\/p>\n

\u7ea4\u7ef4\u6027\u809d\u786c\u5316\u3001\u80be\u786c\u5316\uff0c\u76ae\u80a4\u7622\u75d5\u7624\uff0c\u574f\u8840\u75c5\uff08scurvy\uff09\uff0c\u57c3\u52d2\u65af-\u5f53\u6d1b\u65af\u7efc\u5408\u5f81\uff08Ehlers-Danlos Syndrome\uff0cEDS\uff09\uff0c\u9ee7\u8c46\u75c5\uff08lathyrism\uff09\uff0c\u88c2\u76ae\u75c5\uff08dermatosparaxis\uff09<\/p>\n

\u4ea7\u751f\u80f6\u539f\u7684\u7ec6\u80de\uff1a\u6210\u7ea4\u7ef4\u7ec6\u80de\uff0c\u6e90\u4e8e\u95f4\u5145\u8d28\u7684\u7ec6\u80de\u5982\u6210\u9aa8\u7ec6\u80de\u3001\u8f6f\u9aa8\u7ec6\u80de\u3001\u5e73\u6ed1\u808c\u7ec6\u80de\u7b49\uff1b\u591a\u79cd\u4e0a\u76ae\u7ec6\u80de\u53ca\u795e\u7ecf\u7ec4\u7ec7\u7684\u795e\u7ecf\u819c\u7ec6\u80de<\/p>\n

\u5408\u6210\u548c\u5206\u6ccc\u80f6\u539f\u86cb\u767d\u9176\u7684\u7ec6\u80de\uff1a\u6210\u7ea4\u7ef4\u7ec6\u80de\uff0c\u6ed1\u819c\u7ec6\u80de\uff0c\u591a\u5f62\u6838\u767d\u7ec6\u80de\uff0c\u5de8\u566c\u7ec6\u80de\uff0c\u809d\u7ec6\u80de\uff0c\u67d0\u4e9b\u4e0a\u76ae\u7ec6\u80de<\/p>\n

9 \u5f39\u6027\u7ea4\u7ef4<\/p>\n

\u758f\u677e\u7ed3\u7f14\u7ec4\u7ec7\u5185\u7684\u5f39\u6027\u7ea4\u7ef4\u8f83\u5c11\uff0c\u4eba\u4f53\u5185\u5f39\u6027\u7ea4\u7ef4\u5206\u5e03\u5e7f\u6cdb\uff0c\u96c6\u4e2d\u5728\u627f\u53d7\u4f38\u5c55\u548c\u6269\u5f20\u7684\u7ec4\u7ec7\uff0c\u5982\u771f\u76ae\u3001\u690e\u5f13\u95f4\u9ec4\u97e7\u5e26\u3001\u9879\u97e7\u5e26\u3001\u58f0\u5e26\u3001\u80ba\u6ce1\u9694\u3001\u5f39\u6027\u52a8\u8109\u548c\u5f39\u6027\u8f6f\u9aa8\u7b49<\/p>\n

\u65b0\u9c9c\u65f6\u5f39\u6027\u7ea4\u7ef4\u5448\u9ec4\u8272\uff08\u9ec4\u7ea4\u7ef4\uff09<\/p>\n

\u5149\u955c\u4e0b\uff0c\u94fa\u7247\u6807\u672c\uff0c\u5f39\u6027\u7ea4\u7ef4\u5f88\u7ec6\uff0c\u76f4\u5f841~10\u339b\uff0c\u76f4\u884c\uff0c\u53ef\u6709\u5206\u652f\uff0c\u65ad\u7aef\u5e38\u5377\u66f2<\/p>\n

\u5bcc\u4e8e\u5f39\u6027<\/p>\n

\u5f39\u6027\u7ea4\u7ef4\u548c\u5f39\u6027\u7ed3\u6784\u6298\u5149\u6027\u5f88\u5f3a\uff0c\u4f46\u4e0d\u5177\u53cc\u6298\u5149\u6027\uff0c\u7528\u7d2b\u5916\u5149\u89c2\u5bdf\u5448\u5f31\u767d\u8272\u8367\u5149<\/p>\n

HE\u67d3\u8272\u6807\u672c\u4e0a\u4e0d\u6613\u4e0e\u80f6\u539f\u7ea4\u7ef4\u533a\u522b\u3002\u5e38\u7528Weigert resorcinol-fuchsin\u67d3\u8272\u6cd5\u663e\u793a\u3002\u5730\u8863\u7ea2\uff08orcein\uff09\u68c0\u6d4b\u5e7c\u5e74\u7ec4\u7ec7\u4e2d\u7ea4\u7ec6\u7684\u5f39\u6027\u7ed3\u6784\u3002\u7528\u8367\u5149\u67d3\u6599\u56db\u672c\u57fa\u535f\u915a\u663e\u793a\u5f39\u6027\u7ed3\u6784\uff0c\u5728\u7d2b\u5916\u5149\u4e0b\u53d1\u4eae\u7d2b\u81f3\u73ab\u7470\u7ea2\u8272\u3002\u672a\u5b8c\u5168\u53d1\u80b2\u6210\u719f\u7684\u5f39\u6027\u7ed3\u6784\u53ef\u7528\u78f7\u94a8\u9178\u82cf\u6728\u7cbe\u67d3\u8272\uff0c\u53d1\u80b2\u6210\u719f\u53ca\u8001\u5316\u7684\u5f39\u6027\u7ed3\u6784\u80fd\u7528\u9ad8\u9530\u9178\u94be\u663e\u793a<\/p>\n

\u5f39\u6027\u7ed3\u6784\u8010\u716e\u6cb8\uff0c\u6297\u7a00\u9178\u548c\u7a00\u78b1\uff0c\u80fd\u62b5\u6297\u5927\u591a\u6570\u86cb\u767d\u6c34\u89e3\u9176\u7684\u6c34\u89e3\uff0c\u6613\u88ab\u80f0\u817a\u548c\u591a\u5f62\u6838\u767d\u7ec6\u80de\u5206\u6ccc\u7684\u5f39\u6027\u86cb\u767d\u9176\u7834\u574f<\/p>\n

\u7535\u955c\u4e0b\uff0c\u5f39\u6027\u7ea4\u7ef4\u7531\u4e2d\u592e\u65e0\u5b9a\u5f62\u7684\u6838\u5fc3\u90e8\u5206\uff08\u5f39\u6027\u86cb\u767d\uff09\u548c\u5468\u56f4\u73af\u7ed5\u7684\u5fae\u539f\u7ea4\u7ef4\u7ec4\u6210\uff0c\u4f7f\u5f39\u6027\u7ea4\u7ef4\u5448\u4e0d\u89c4\u5219\u7684\u6bdb\u523a\u68d2\u72b6\u4f53\u3002<\/p>\n

\u5f39\u6027\u86cb\u767d\uff08Elastin\uff09\u4e0d\u6eb6\u4e8e\u6c34\uff0c\u5177\u6709\u6a61\u80f6\u822c\u80fd\u4f38\u5c55\u548c\u6536\u7f29\u7684\u5f39\u6027\uff0c\u662f\u5f39\u6027\u7ea4\u7ef4\u7684\u4e3b\u8981\u6210\u5206\uff0c\u5e7f\u6cdb\u5206\u5e03\u4e8e\u5168\u8eab\u7684\u808c\u80a4\u3001\u810f\u5668\u3001\u8109\u7ba1\u58c1\u548c\u97e7\u5e26\u4e2d\uff0c\u4e0e\u80f6\u539f\u86cb\u767d\u6346\u624e\u5171\u5b58\u3002\u76f4\u5f8430~40nm\uff0c\u4e1d\u72b6\u6392\u5217\uff0c\u5355\u4f4d\u538b\u529b4.0\u7684\u8f74\u6027\u5468\u671f\uff1b<\/p>\n

\u5fae\u539f\u7ea4\u7ef4\u4e3b\u8981\u7531\u5206\u5b50\u8f83\u5927\u7684\u539f\u7ea4\u7ef4\u86cb\u767d\uff08fibrillin\uff09\u6784\u6210\u3002<\/p>\n

\u5f39\u6027\u7ea4\u7ef4\u7684\u4e09\u4e2a\u9636\u6bb5\uff1a<\/p>\n

\u65e9\u671f\u5f39\u6027\u7ea4\u7ef4\uff0c\u7531\u7cd6\u86cb\u767d\u6784\u6210\u7684\u5fae\u539f\u7ea4\u7ef4\u675f\uff0c\u7531\u76f4\u5f8410~16nm\u7684\u5fae\u7ba1\u7ec4\u6210\u3002Gomori\u67d3\u5fae\u539f\u7ea4\u7ef4\u675f\uff0c\u9700\u7ecf\u4e59\u9178\u6c27\u5316\u540e\u624d\u7740\u8272\u3002\u53ef\u5b58\u5728\u4e8e\u776b\u72b6\u5c0f\u5e26\u548c\u76ae\u80a4\uff0c\u5177\u8010\u9178\u6027\uff0c\u79f0\u8010\u9178\u7ea4\u7ef4<\/p>\n

\u4e2d\u671f\u5f39\u6027\u7ea4\u7ef4\uff0c\u7ec6\u7ea4\u7ef4\u4e4b\u95f4\u51fa\u73b0\u4e0d\u89c4\u5219\u7684\u5f39\u6027\u86cb\u767d\u6c89\u7740\uff0c\u7ea4\u7ef4\u5f39\u6027\u589e\u5f3a\u3002\u53ef\u5b58\u5728\u4e8e\u76ae\u80a4\u7684\u6c57\u817a\u5468\u56f4<\/p>\n

\u6210\u719f\u7684\u5f39\u6027\u7ea4\u7ef4\uff0c\u5f39\u6027\u86cb\u767d\u805a\u96c6\uff0c\u76f4\u5230\u5360\u636e\u7ea4\u7ef4\u4e2d\u592e\uff0c\u5176\u5916\u518d\u73af\u7ed5\u4e00\u8584\u5c42\u5fae\u539f\u7ea4\u7ef4\uff0c\u6210\u4e3a\u5f39\u6027\u7ea4\u7ef4\u3002\u6210\u7ea4\u7ef4\u7ec6\u80de\u3001\u5e73\u6ed1\u808c\u7ec6\u80de\u53ca\u8f6f\u9aa8\u7ec6\u80de\u5408\u6210\u548c\u5206\u6ccc\u5fae\u539f\u7ea4\u7ef4\u86cb\u767d\u548c\u5f39\u6027\u86cb\u767d\u3002\u7ec6\u80de\u7684\u7c97\u9762\u5185\u8d28\u7f51\u4e0a\u5408\u6210\u53ef\u6eb6\u6027\u524d\u5f39\u6027\u86cb\u767d\uff08proelastin\uff09<\/p>\n

\u677e\u76ae\u75c7\uff0c\u8d56\u6c28\u9178\u6c27\u5316\u9176\u6d3b\u6027\u964d\u4f4e\u6216\u5176\u8f85\u52a9\u56e0\u5b50\u7f3a\u4e4f\uff0c\u5f39\u6027\u7ea4\u7ef4\u751f\u6210\u969c\u788d<\/p>\n

\u7ed9\u9e21\u548c\u732a\u5582\u7f3a\u94dc\u98df\u7269\uff0c\u5219\uff1a\u8840\u7ba1\u8106\u6027\u589e\u52a0\uff0c\u4f34\u76ae\u4e0b\u4e0e\u5185\u810f\u51fa\u8840\u3002\u955c\u4e0b\uff0c\u52a8\u8109\u5f39\u6027\u6210\u5206\u65ad\u88c2\uff0c\u5185\u5f39\u6027\u819c\u788e\u88c2\uff0c\u4ea4\u8054\u7f3a\u9677\u7684\u5f39\u6027\u786c\u86cb\u767d<\/p>\n

\u83b7\u5f97\u6027\u76ae\u80a4\u677e\u5f1b\u75c7\uff0c\u539f\u7ea4\u7ef4\u86cb\u767d\u5f02\u5e38\uff0c\u5fae\u539f\u7ea4\u7ef4\u51cf\u5c11\uff1b\u5c40\u9650\u6027\u6216\u7cfb\u7edf\u6027\u786c\u76ae\u75c5\uff0c\u5fae\u539f\u7ea4\u7ef4\u589e\u591a\uff0c\u6563\u5728\u4e8e\u80f6\u539f\u4e4b\u95f4<\/p>\n

10 \u7f51\u72b6\u7ea4\u7ef4<\/p>\n

\u4e3b\u8981\u7531\u2162\u578b\u80f6\u539f\u86cb\u767d\u6784\u6210\uff0c\u5e38\u4f34\u5176\u4ed6\u7c7b\u578b\u7684\u80f6\u539f\u3001\u86cb\u767d\u591a\u7cd6\u548c\u7cd6\u86cb\u767d<\/p>\n

\u758f\u677e\u7ed3\u7f14\u7ec4\u7ec7\u5185\u7f51\u72b6\u7ea4\u7ef4\u8f83\u5c11\uff0c\u7f51\u72b6\u7ec4\u7ec7\u5185\u7684\u7f51\u72b6\u7ea4\u7ef4\u4e30\u5bcc\uff0c\u5e38\u89c1\u4e8e\u8102\u80aa\u7ec6\u80de\u8868\u9762\uff1b\u5b58\u5728\u4e8e\u5b9e\u8d28\u5668\u5b98\uff08\u809d\u3001\u80be\u3001\u5185\u5206\u6ccc\u817a\uff09\u5185\uff0c\u4ee5\u53ca\u6784\u6210\u6dcb\u5df4\u7ed3\u3001\u813e\u548c\u9aa8\u9ad3\u7684\u652f\u67b6<\/p>\n

\u7ea4\u7ef4\u5e38\u5206\u5e03\u5728\u5668\u5b98\u5b9e\u8d28\u7ec6\u80de\u3001\u5e73\u6ed1\u808c\u7ec6\u80de\u3001\u817a\u6ce1\u548c\u6bdb\u7ec6\u8840\u7ba1\u5468\u56f4\uff1b\u5206\u5e03\u5728\u57fa\u819c\u7684\u7f51\u677f\u5185\uff0c\u6ca1\u6709\u7f51\u677f\u7684\u57fa\u819c\u5982\u80be\u5c0f\u7403\u57fa\u819c\uff0c\u4e5f\u6ca1\u6709\u2162\u578b\u80f6\u539f\u6216\u7f51\u72b6\u7ea4\u7ef4<\/p>\n

\u7f51\u72b6\u7ea4\u7ef4\u7279\u522b\u7ea4\u7ec6\uff0c\u76f4\u5f840.2~1.0\u339b\uff0c\u88ab\u94f6\u76d0\u6d78\u67d3\u5448\u9ed1\u8272\uff0c\u79f0\u55dc\u94f6\u7ea4\u7ef4<\/p>\n

\u7531\u76f4\u5f8435nm\u7684\u7ec6\u539f\u7ea4\u7ef4\u7ec4\u6210\uff0c\u539f\u7ea4\u7ef4\u95f4\u7531\u86cb\u767d\u591a\u7cd6\u548c\u7cd6\u86cb\u767d\u6784\u6210\u7684\u6865\u72b6\u7ed3\u6784\u76f8\u8fde<\/p>\n

\u5177\u6709\u55dc\u94f6\u6027\u548cPAS\u9633\u6027<\/p>\n<\/p>\n

\u732b\u6dcb\u5df4\u7ed3\u9540\u94f6\uff08\u7f51\u72b6\u7ea4\u7ef4\uff09<\/p>\n

11\u57fa\u8d28<\/p>\n

\u6c34\u5316\u65e0\u5b9a\u5f62\u7269\u8d28\uff0c\u4e3b\u8981\u7531\u86cb\u767d\u591a\u7cd6\u548c\u7cd6\u86cb\u767d\u7b49\u7ec4\u6210<\/p>\n

\uff081\uff09\u86cb\u767d\u591a\u7cd6\uff08proteoglycan\uff09<\/p>\n

\u86cb\u767d\u5206\u5b50\u4e0e\u591a\u7cd6\u5206\u5b50\u7ed3\u5408\u7684\u590d\u5408\u7269<\/p>\n

\u591a\u7cd6\uff1a\u6c28\u57fa\u5df1\u7cd6\u591a\u7cd6\uff08\u9ecf\u591a\u7cd6\u3001\u7cd6\u80fa\u591a\u7cd6\uff09<\/p>\n

\u786b\u9178\u76ae\u80a4\u7d20<\/p>\n

\u786b\u9178\u4e59\u9170\u809d\u7d20<\/p>\n

\u786b\u9178\u8f6f\u9aa8\u7d20<\/p>\n

\u786b\u9178\u89d2\u8d28\u7d20<\/p>\n

\u809d\u7d20<\/p>\n

\u900f\u660e\u8d28\u9178<\/p>\n<\/p>\n

\u57fa\u8d28\u7684\u663e\u793a\uff1a<\/p>\n

\u51b0\u51bb\u5207\u7247\uff0c\u56fa\u5b9a\u6db2\u52a0\u5165\u6c2f\u5316\u5341\u516d\u70f7\u57fa\u94f5\u57fa\u5421\u5576\uff08cethylpyridinium chloride\uff09\uff0c\u539f\u4f4d\u663e\u793a\u86cb\u767d\u591a\u7cd6<\/p>\n

\u86cb\u767d\u591a\u7cd6\u7684GAG\u90e8\u5206\u6709\u8bb8\u591a\u9178\u6839\uff0c\u6613\u4e3a\u78b1\u6027\u67d3\u6599\u7740\u8272\u3002\u4ee5\u9152\u7cbe\u4f5c\u6eb6\u5242\u7684\u9633\u79bb\u5b50\u67d3\u6599\uff0c\u5982\u7532\u82ef\u80fa\u84dd\u67d3\u8272\uff0c\u57fa\u8d28\u5177\u5f02\u67d3\u6027<\/p>\n

\u7528\u4e8e\u663e\u793a\u6c28\u57fa\u5df1\u7cd6\u591a\u7cd6\u7684\u67d3\u6599\u6709\u567b\u55ea\u3001\u963f\u5229\u65b0\u84dd\u3001\u80f6\u4f53\u94c1\u548c\u80f6\u4f53\u91d1\u3002\u948c\u7ea2\u3001\u785d\u9178\u94cb\u53ca\u4e9a\u94dc\u7c7b\u67d3\u6599cuprolinic blue\u548ccepromeronic blue\uff0c\u80fd\u4e0e\u6c28\u57fa\u5df1\u7cd6\u591a\u7cd6\u7ed3\u5408\u4ea7\u751f\u7535\u5b50\u81f4\u5bc6\u7684\u5316\u5408\u7269\uff0c\u6545\u5e38\u7528\u86cb\u767d\u591a\u7cd6\u7684\u7535\u955c\u7ec4\u5316\u7814\u7a76<\/p>\n

\u57fa\u8d28\u7684\u591a\u6570\u86cb\u767d\u591a\u7cd6\u4e0e\u8fc7\u7898\u9178\u53cd\u5e94\u7f13\u6162\uff0c\u4e0d\u80fd\u7528PAS\u663e\u8272\uff1b\u786b\u9178\u89d2\u8d28\u7d20\u86cb\u767d\u591a\u7cd6\uff0cPAS\u9633\u6027<\/p>\n

\u7ed3\u6784\u6027\u86cb\u767d\uff08\u57fa\u8d28\u7cd6\u86cb\u767d\uff09\uff1a<\/p>\n

\u7ea4\u7ef4\u9ecf\u8fde\u86cb\u767d\uff08FN\uff09\uff0c\u5c42\u9ecf\u8fde\u86cb\u767d\uff08LN\uff09\uff0c\u884c\u52a8\u7d20\u6216\u7740\u4f4d\u7d20\u6216\u5de2\u86cb\u767d\uff0c\u8840\u6813\u9ecf\u5408\u7d20\uff08TSP\uff09\uff0c\u7ec6\u80de\u9910\u9ecf\u8fde\u86cb\u767d\uff08VN\uff09\uff0c\u8f6f\u9aa8\u9ecf\u8fde\u86cb\u767d\uff08ChN\uff09\uff0c\u9aa8\u9ecf\u8fde\u86cb\u767d\uff08ON\uff09\uff0c\u6bfd\u86cb\u767d\uff08TN\uff09\uff0c\u7c97\u7ea4\u7ef4\u8c03\u8282\u7d20<\/p>\n

\u7ec4\u7ec7\u6db2\uff1a\u7ec6\u80de\u95f4\u8d28\u4e2d\u7684\u6c34\u548c\u6eb6\u4e8e\u5176\u4e2d\u7684\u7269\u8d28<\/p>\n<\/p>\n

\u7b2c\u4e8c\u90e8\u5206  \u7ed3\u7f14\u7ec4\u7ec7\u75c5<\/p>\n

\u7ed3\u7f14\u7ec4\u7ec7\u75c5\u5305\u62ec\u7ea2\u6591\u72fc\u75ae\u3001\u786c\u76ae\u75c5\u3001\u76ae\u808c\u708e\u3001\u7c7b\u98ce\u6e7f\u6027\u5173\u8282\u708e\u3001\u7ed3\u8282\u6027\u591a\u52a8\u8109\u708e\u3001\u97e6\u683c\u7eb3\u8089\u82bd\u80bf\u3001\u5de8\u7ec6\u80de\u52a8\u8109\u708e\u53ca\u5e72\u71e5\u7efc\u5408\u5f81\u7b49\u3002<\/p>\n

\u4e00\u3001\u7ea2\u6591\u72fc\u75ae\uff08lupus erythematosus\uff09<\/p>\n

\u6162\u6027\u3001\u53cd\u590d\u53d1\u4f5c\u7684\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u7684\u603b\u79f0\uff0c\u5e38\u89c1\u4e8e\u80b2\u9f84\u671f\u5973\u6027\u3002\u7ea2\u6591\u72fc\u75ae\u6700\u5177\u7279\u5f81\u6027\u7684\u75c7\u72b6\u4e3a\u9762\u988a\u90e8\u51fa\u73b0\u8776\u5f62\u7ea2\u6591\uff0c\u800c\u201c\u72fc\u75ae\u201d\u7684\u540d\u5b57\u6b63\u662f\u56e0\u4e3a\u8fc7\u53bb\u4eba\u4eec\u8ba4\u4e3a\u8be5\u75c5\u7684\u9762\u90e8\u7ea2\u6591\u8868\u73b0\uff0c\u50cf\u662f\u88ab\u72fc\u54ac\u4f24\u6240\u81f4\u3002\u800c\u9664\u76ae\u80a4\u635f\u5bb3\u4ee5\u5916\uff0c\u7ea2\u6591\u72fc\u75ae\u7684\u75c5\u53d8\u8fd8\u53ef\u7d2f\u53ca\u591a\u810f\u5668\u548c\u7cfb\u7edf\u3002\u7ea2\u6591\u72fc\u75ae\u4ecd\u7f3a\u4e4f\u6839\u6cbb\u624b\u6bb5\uff0c\u4f46\u901a\u8fc7\u65e9\u671f\u8bca\u65ad\u53ca\u89c4\u8303\u6027\u7684\u7efc\u5408\u6cbb\u7597\uff0c\u672c\u75c5\u7684\u9884\u540e\u53ef\u660e\u663e\u6539\u5584\uff0c\u7edd\u5927\u591a\u6570\u60a3\u8005\u75c5\u60c5\u53ef\u63a7\u5236\uff0c\u80fd\u6b63\u5e38\u5de5\u4f5c\u3001\u751f\u6d3b\u3001\u751f\u80b2\u7b49\u3002<\/p>\n<\/p>\n

\u7ea2\u6591\u72fc\u75ae<\/p>\n<\/p>\n

\u76d8\u72b6\u7ea2\u6591\u72fc\u75ae<\/p>\n

\u4e8c\u3001\u786c\u76ae\u75c5\uff08scleroderma\uff09<\/p>\n

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\u8102\u6027\u786c\u76ae\u75c5<\/p>\n

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\u56db\u3001\u7c7b\u98ce\u6e7f\u5173\u8282\u708e\uff08rheumatoid arthritis\uff09<\/p>\n

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\u516d\u3001\u97e6\u683c\u7eb3\uff08Wegener\uff09\u8089\u82bd\u80bf<\/p>\n

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