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\u94be\u7ade\u4e89\u6027\u9178\u963b\u65ad\u5242\uff08potassium-competitive acid blockers\uff0cP-CABs\uff09\u662f\u4e00\u7c7b\u65b0\u578b\u6291\u9178\u836f\u7269\uff0c\u662f H\u207a\/K\u207a- ATP \u9176\u7684\u7ade\u4e89\u6027\u53ef\u9006\u6291\u5236\u5242\uff0c\u80fd\u591f\u901a\u8fc7\u963b\u65ad K\u207a \u4e0e\u9176\u7684\u7ed3\u5408\u53d1\u6325\u4f5c\u7528\u3002<\/p>\n

P-CABs \u65e0\u9700\u5728\u5f3a\u9178\u73af\u5883\u4e0b\u6d3b\u5316\u5373\u53ef\u53d1\u6325\u4f5c\u7528\uff0cP-CABs \u5bf9\u9178\u7a33\u5b9a\uff0c\u5728\u80c3\u9178\u4e2d\u4e0d\u88ab\u964d\u89e3\uff0c\u56e0\u6b64\u53ef\u4ee5\u53e3\u670d\u7ed9\u836f\uff0c\u800c\u4e0d\u9700\u8981\u5236\u5907\u80a0\u6eb6\u5236\u5242\u3002<\/p>\n

P-CABs \u80fd\u591f\u4e0e\u9759\u606f\u6cf5\u7ed3\u5408\uff0c\u4e14\u4e0e H\u207a\/K\u207a- ATP \u9176\u89e3\u79bb\u7f13\u6162\uff0c\u56e0\u6b64\u5177\u6709\u5feb\u901f\u3001\u6709\u6548\u3001\u7a33\u5b9a\u548c\u6301\u4e45\u7684\u9178\u6291\u5236\u4f5c\u7528\u3002<\/p>\n

\u76ee\u524d\u56fd\u5185\u4e0a\u5e02\u7684\u6709\u4f0f\u8bfa\u62c9\u751f\u3001\u66ff\u6208\u62c9\u751f\u3001\u51ef\u666e\u62c9\u751f 3 \u79cd P-CABs\u3002\u73b0\u5c06 3 \u79cd P-CABs \u7684\u76f8\u5173\u836f\u5b66\u4fe1\u606f\u4f5c\u4e00\u603b\u7ed3\u6bd4\u8f83\u3002<\/p>\n

1<\/p>\n

\u8bf4\u660e\u4e66\u6279\u51c6\u9002\u5e94\u8bc1<\/p>\n

2<\/p>\n

\u7528\u6cd5\u7528\u91cf<\/p>\n

3<\/p>\n

\u7279\u6b8a\u4eba\u7fa4\u7528\u836f\u60c5\u51b5<\/p>\n

4<\/p>\n

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*NC821602 \u7814\u7a76\u4e2d\u8840\u80c3\u6ccc\u7d20\u66ff\u6208\u62c9\u751f\u7ec4\u5347\u9ad8\u8005\u6bd4\u4f8b\u548c\u5e73\u5747\u5347\u9ad8\u5e45\u5ea6\u4e0e\u827e\u53f8\u5965\u7f8e\u62c9\u5511\u7ec4\u76f8\u6bd4\u65e0\u7edf\u8ba1\u5b66\u5dee\u5f02\uff0c\u4e00\u822c\u5728\u6cbb\u7597\u7ed3\u675f\u540e 1\uff5e3 \u4e2a\u6708\u6062\u590d\u81f3\u6b63\u5e38<\/p>\n

5<\/p>\n

\u836f\u7269\u76f8\u4e92\u4f5c\u7528<\/p>\n

1\uff09\u672c\u7c7b\u836f\u7269\u4f1a\u5bfc\u81f4\u80c3\u5185 pH \u5347\u9ad8\uff0c\u63d0\u793a\u5bf9\u4e8e\u80c3\u5185 pH \u662f\u53e3\u670d\u751f\u7269\u5229\u7528\u5ea6\u91cd\u8981\u51b3\u5b9a\u56e0\u7d20\u7684\u836f\u7269\uff0c\u53ef\u80fd\u5f71\u54cd\u5176\u5438\u6536\u3002<\/p>\n

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