{"id":32782,"date":"2024-05-07T12:01:15","date_gmt":"2024-05-07T12:01:15","guid":{"rendered":"https:\/\/zydq.1006ss.com\/?p=32782"},"modified":"2024-05-07T12:01:15","modified_gmt":"2024-05-07T12:01:15","slug":"%e3%80%90%e8%a1%a1%e9%81%93%e5%ad%a6%e4%b9%a0%e7%ac%94%e8%ae%b0%e3%80%91%e6%98%93%e8%af%af%e8%af%8a%e4%b8%ba%e6%b7%8b%e5%b7%b4%e7%98%a4%e7%9a%84%e5%8f%8d%e5%ba%94%e6%80%a7%e6%b7%8b%e5%b7%b4%e7%bb%93","status":"publish","type":"post","link":"http:\/\/zydq.1006ss.com\/?p=32782","title":{"rendered":"\u3010\u8861\u9053\u5b66\u4e60\u7b14\u8bb0\u3011\u6613\u8bef\u8bca\u4e3a\u6dcb\u5df4\u7624\u7684\u53cd\u5e94\u6027\u6dcb\u5df4\u7ed3\u75c5"},"content":{"rendered":"

\u672c\u7cfb\u5217\u7b14\u8bb0\u6839\u636e\u3010\u8861\u9053\u75c5\u7406\u3011\u6dcb\u5df4\u7624\u4f53\u7cfb\u8bfe\u7a0b\u6574\u7406\uff0c\u672c\u6587\u4f9d\u636e\u6731\u96c4\u589e\u8001\u5e08\u7b2c\u4e8c\u8bb2\u5185\u5bb9\u6574\u7406\uff0c\u5e0c\u671b\u5e2e\u5230\u5927\u5bb6\u3002<\/h2>\n

\u6613\u8bef\u8bca\u4e3a\u6dcb\u5df4\u7624\u7684\u53cd\u5e94\u6027\u6dcb\u5df4\u7ed3\u75c5\u53ef\u4ee5\u5206\u6210\u4e24\u4e2a\u90e8\u5206\uff0c\u4e00\u662f\u4e34\u5e8a\u533b\u751f\u5bb9\u6613\u8bef\u8bca\u4e3a\u6dcb\u5df4\u7624\u7684\u75be\u75c5\uff0c\u6bd4\u5982Castleman\u75c5\u3001\u7ed3\u8282\u75c5\u3001Rosai-Dorfamn\u75c5\uff08\u4f34\u5de8\u5927\u6dcb\u5df4\u7ed3\u75c5\u7684\u7aa6\u7ec4\u7ec7\u7ec6\u80de\u589e\u751f\u75c7\u3001SHML\uff09\u7b49\uff1b\u4e00\u662f\u75c5\u7406\u533b\u751f\u5bb9\u6613\u8bef\u8bca\u4e3a\u6dcb\u5df4\u7624\u7684\u75be\u75c5\uff0c\u5982\u4f20\u67d3\u6027\u5355\u6838\u7ec6\u80de\u589e\u751f\u75c7\u3001Kikuchi\u75c5\u3001\u732b\u6293\u75c5\u3001\u76ae\u75c5\u6027\u6dcb\u5df4\u7ed3\u708e\u3001\u81ea\u8eab\u514d\u75ab\u6dcb\u5df4\u7ec6\u80de\u589e\u751f\u6027\u7efc\u5408\u5f81\u7b49\u3002<\/p>\n

Castleman\u75c5<\/h2>\n

\u7eb5\u9694\/\u8179\u8154\u6dcb\u5df4\u7ed3\u80bf\u5927\uff0c\u4e34\u5e8a\u5bb9\u6613\u8bef\u8bca\u4e3a\u6076\u6027\u6dcb\u5df4\u7624\u3002<\/p>\n<\/p>\n

Castleman\u75c5\u76843\u4e2a\u7c7b\u578b\uff1a\u5c40\u9650\u6027\u73bb\u7483\u6837\u8840\u7ba1\u578bCastleman\u75c5\uff08HV-CD\uff09\u3001\u5c40\u9650\u6027\u6d46\u7ec6\u80de\u578bCastleman\u75c5\uff08PC-CD\uff09\u3001\u591a\u4e2d\u5fc3\u6027Castleman\u75c5\uff08MCD\uff09\u3002<\/p>\n

Castleman\u75c5\u73b0\u4ee3\u5206\u7c7b\uff1a\u975eHHV8\u76f8\u5173\uff1a\u5355\u4e2d\u5fc3\u5c40\u9650\u6027\u73bb\u7483\u6837\u8840\u7ba1\u578bCastleman\u75c5\u3001\u5355\u4e2d\u5fc3\u5c40\u9650\u6027\u6d46\u7ec6\u80de\u578bCastleman\u75c5\u3001\u591a\u4e2d\u5fc3\u5c40\u9650\u6027\u6d46\u7ec6\u80de\u578bCastleman\u75c5\uff1bHHV8\u76f8\u5173\uff1a\u4e0d\u4f34\u6709\u6d46\u6bcd\u7ec6\u80de\u6dcb\u5df4\u7624\uff08HHV8 MCD\uff09\u3001\u4f34\u6709\u6d46\u6bcd\u7ec6\u80de\u6dcb\u5df4\u7624\uff08HHV8 PBL\uff09\u3002<\/p>\n<\/p>\n

\u5c40\u9650\u6027\u73bb\u7483\u6837\u8840\u7ba1\u578bCastleman\u75c5\uff08HV-CD\uff09<\/h3>\n

1\uff0e\u6dcb\u5df4\u7ed3\u5305\u819c\u589e\u539a\uff0c\u6dcb\u5df4\u7aa6\u51cf\u5c11\u6216\u6d88\u5931\uff1b<\/p>\n

2\uff0e\u6ee4\u6ce1\uff1a\u751f\u53d1\u4e2d\u5fc3\u840e\u7f29\uff0c\u5f02\u5e38\u73bb\u7483\u6837\u8840\u7ba1\u7a7f\u5165\uff0c\u5957\u533a\u7ec6\u80de\u589e\u751f\u4fb5\u5165\u751f\u53d1\u4e2d\u5fc3\uff0c\u540c\u5fc3\u5706\u6392\u5217\uff0c\u5c06\u840e\u7f29\u7684\u6ee4\u6ce1\u5206\u9694\u6210\u4e00\u4e2a\u6216\u591a\u4e2a\uff0c\u751f\u53d1\u4e2d\u5fc3\u5185\u6ee4\u6ce1\u6811\u7a81\u72b6\u7ec6\u80de\uff08FDC\uff09\u5e38\u663e\u8457\u589e\u751f\uff08CD21\u9633\u6027\uff09\u8fd8\u53ef\u80fd\u53d1\u751f\u6ee4\u6ce1\u6811\u7a81\u7ec6\u80de\u8089\u7624\uff1b<\/p>\n

3\uff0e\u526f\u76ae\u8d28\u533a\uff1a\u9ad8\u5ea6\u5bcc\u4e8e\u8840\u7ba1\uff0c\u8840\u7ba1\u58c1\u4e5f\u53ef\u73bb\u7483\u6837\u53d8\uff0c\u8840\u7ba1\u95f4\u4e3a\u5bc6\u96c6\u5c0f\u6dcb\u5df4\u7ec6\u80de\uff0c\u901a\u5e38\u65e0\u5927\u6dcb\u5df4\u7ec6\u80de\u548c\u6d46\u7ec6\u80de\uff0c\u53ef\u89c1\u6d46\u7ec6\u80de\u6837\u6811\u7a81\u7ec6\u80de\u589e\u751f\uff08CD123 \uff09\u3002<\/p>\n

 <\/p>\n

\u5c40\u9650\u6027\u6d46\u7ec6\u80de\u578bCastleman\u75c5\uff08PC-CD\uff09<\/h3>\n

1.\u6dcb\u5df4\u7ed3\u6ee4\u6ce1\u6563\u5728\u5206\u5e03\u3001\u5957\u533a\u5b58\u5728\u3001\u6dcb\u5df4\u7aa6\u5b8c\u6574\uff1b<\/p>\n

2.\u526f\u76ae\u8d28\u533a\u548c\u9ad3\u8d28\u5927\u91cf\u6210\u719f\u6d46\u7ec6\u80de\u589e\u751f\uff0c\u7ea6\u534a\u6570\u6d46\u7ec6\u80deLambda \u3001Kappa-\uff0c\u5f53Kappa \u65f6\u4e0d\u8003\u8651\u672c\u75c5\uff1b<\/p>\n

3.\u8840\u6e05IL-6\u5e38\u5347\u9ad8\u3002<\/p>\n

\u591a\u4e2d\u5fc3\u6027Castleman\u75c5\uff08MCD\uff09<\/h3>\n

\u4e0e\u5c40\u9650\u6027\u6d46\u7ec6\u80de\u578bCastleman\u75c5\uff08PC-CD\uff09\u76f8\u4f3c\uff1b\u5957\u533a\u754c\u9650\u6a21\u7cca\uff0c\u6ee4\u6ce1\u6eb6\u89e3\uff1b<\/p>\n

\u6d46\u7ec6\u80de\u548c\u6d46\u6bcd\u7ec6\u80de\u53ef\u6709\u975e\u5178\u578b\u6027\uff08\u53ef\u8fdb\u5c55\u4e3a\u6d46\u6bcd\u7ec6\u80de\u6dcb\u5df4\u7624\uff09\uff0c\u6dcb\u5df4\u7aa6\u4ecd\u5b58\u5728\uff0c\u8840\u7ba1\u660e\u663e\u589e\u751f\uff0c\u6d46\u7ec6\u80de\u548c\u6d46\u6bcd\u7ec6\u80deIg\u4e3a\u591a\u514b\u9686\u6027\uff08\u662f\u5176\u4e0d\u8bca\u65ad\u6dcb\u5df4\u7624\u7684\u539f\u56e0\uff09\u3002<\/p>\n

 <\/p>\n

\u4e0d\u4f34\u6709\u6d46\u6bcd\u7ec6\u80de\u6dcb\u5df4\u7624\uff08HHV8 MCD\uff09<\/h3>\n

\u76f8\u4f3c\u4e8e\u591a\u4e2d\u5fc3PC-MCD\uff0c\u6d46\u6bcd\u7ec6\u80de\u53ef\u4ee5\u4f4d\u4e8e\u751f\u53d1\u4e2d\u5fc3\u5185\u548c\u751f\u53d1\u4e2d\u5fc3\u5916\uff0c\u5f53\u6d46\u7ec6\u80de\u805a\u96c6\u4e8e\u751f\u53d1\u4e2d\u5fc3\u5185\u5916\u65f6\u53ef\u5f62\u6210\u6240\u8c13\u7684\u5fae\u6dcb\u5df4\u7624\uff1b\u6d46\u6bcd\u7ec6\u80de\u8868\u8fbe\u5355\u514b\u9686IgM\u548cLambda\u3001\u8868\u8fbeHHV8\u3001\u6f5c\u4f0f\u6838\u6297\u539f1\uff08LANA1\u3001ORF73\uff09\u548cIL-6\uff1bIg\u4e3a\u591a\u514b\u9686\u6216\u5355\u514b\u9686\u3002<\/p>\n

\u4f34\u6709\u6d46\u6bcd\u7ec6\u80de\u6dcb\u5df4\u7624HHV8 PBL<\/h3>\n

\u5f53\u975e\u5178\u578b\u6d46\u6bcd\u7ec6\u80de\u5f25\u6f2b\u6210\u7247\u65f6\uff0c\u8bca\u65ad\u4e3aCastleman\u75c5\u4f34\u6d46\u6bcd\u7ec6\u80de\u6dcb\u5df4\u7624\uff1b\u6d46\u6bcd\u7ec6\u80de\u8868\u8fbeIgM\/Lambda\u3001LANA1\u3001IL-6\uff1b\u6b64\u65f6Ig\u4e3a\u5355\u514b\u9686\u3002<\/p>\n<\/p>\n

Castleman\u75c5\u7684\u9274\u522b\u8bca\u65ad<\/h3>\n

\u9274\u522b\u8bca\u65ad\uff1a\u6ee4\u6ce1\u6811\u7a81\u7ec6\u80de\u8089\u7624\uff08\u5982\u4e0b\u56fe\uff09\u3001\u5361\u6ce2\u897f\u8089\u7624\u3001\u6df7\u5408\u7ec6\u80de\u7684\u970d\u5947\u91d1\u6dcb\u5df4\u7624\u3001\u5927B\u7ec6\u80de\u6dcb\u5df4\u7624\u548cT\u7ec6\u80de\u6dcb\u5df4\u7624\u3002<\/p>\n

\u6848\u4f8b\uff1a\u672c\u4f8b\u4e3aCastleman\u75c5\u7684\u57fa\u7840\u4e0a\u53d1\u751f\u4e86\u6ee4\u6ce1\u6811\u7a81\u7ec6\u80de\u8089\u7624\u3002<\/p>\n<\/p>\n

\u7ed3\u8282\u75c5<\/h2>\n

20-40\u5c81\u5973\u6027\uff0c\u7537\u5973\u4e4b\u6bd4\u7ea6\u4e3a1:2\uff1b\u547c\u5438\u9053\u75c7\u72b6\uff08\u54b3\u55fd\u3001\u6c14\u6025\u3001\u80f8\u75db\uff09\uff0c\u53ef\u6709\u53d1\u70ed\u3001\u4e4f\u529b\u3001\u4f53\u91cd\u51cf\u8f7b\u548c\u76d7\u6c57\uff1b<\/p>\n

90%\u53cc\u4fa7\u80ba\u95e8\u548c\u7eb5\u9694\u6dcb\u5df4\u7ed3\u5bf9\u79f0\u6027\u80bf\u5927\u6216\u80ba\u7d2f\u53ca\uff1b\u76ae\u80a4\u3001\u773c\u3001\u6d45\u8868\u6dcb\u5df4\u7ed3\u3001\u809d\u3001\u813e\u3001\u9aa8\u7b49\u4e5f\u53ef\u7d2f\u53ca\uff1b\u8840\u6e05\u8840\u7ba1\u7d27\u5f20\u7d20\u8f6c\u5316\u9176\uff08ACE\uff09\u5347\u9ad8\uff0cKveim\u5b9e\u9a8c\u9633\u6027\uff08\u5c06\u75c5\u4eba\u75c5\u53d8\u7ec4\u7ec7\u6ce8\u5165\u75c5\u4eba\u76ae\u4e0b\u4f1a\u51fa\u73b0\u540c\u6837\u7684\u76ae\u4e0b\u75c5\u53d8\uff09\u3002<\/p>\n

 <\/p>\n

\u7ed3\u8282\u75c5\u75c5\u7406\u5b66\uff1a<\/p>\n

\u8089\u82bd\u80bf\u5883\u754c\u6e05\u695a\uff0c\u7531\u4e0a\u76ae\u6837\u7ec6\u80de\u7ec4\u6210\uff0c\u6563\u5e03\u4e00\u4e9b\u591a\u6838\u5de8\u7ec6\u80de\u3001\u6d46\u7ec6\u80de\u548c\u7ea4\u7ef4\u7ec6\u80de\u7ec4\u6210\uff1b\u8089\u82bd\u80bf\u7684\u4e2d\u592e\u65e0\u574f\u6b7b\uff0c\u5076\u5c14\u6709\u7ea4\u7ef4\u7d20\u6837\u574f\u6b7b\u7076\uff1b\u591a\u6838\u5de8\u7ec6\u80de\u53ef\u4e3a\u5f02\u7269\u578b\u6216Langhans\u578b\uff1b\u80de\u6d46\u5185\u5305\u6db5\u4f53\uff08\u661f\u5f62\u5c0f\u4f53\u3001Schaumann\u5c0f\u4f53\u3001\u8349\u9178\u9499\u7ed3\u6676\u548cHamazaki-Wesenberg\u5c0f\u4f53\uff09\u3002<\/p>\n

 <\/p>\n<\/p>\n

Rosai-Dorfamn\u75c5\uff08\u4f34\u5de8\u5927\u6dcb\u5df4\u7ed3\u75c5\u7684\u7aa6\u7ec4\u7ec7\u7ec6\u80de\u589e\u751f\u75c7\u3001SHML\uff09<\/h2>\n

20\u5c81\u4ee5\u4e0b\u7684\u513f\u7ae5\u548c\u9752\u5c11\u5e74\uff0c\u7537\u6027\u7a0d\u591a\uff1b\u591a\u4e2a\u6dcb\u5df4\u7ed3\uff08\u5c24\u5176\u9888\u90e8\uff09\u80bf\u5927\uff1b40%\u75c5\u4f8b\u7d2f\u53ca\u7ed3\u5916\uff08\u4e0a\u547c\u5438\u9053\u3001\u76ae\u80a4\u3001\u773c\u7736\u3001\u6d8e\u817a\u3001\u8f6f\u7ec4\u7ec7\u3001CNS\uff09\uff1b\u5927\u591a\u6570\u6708\u81f3\u6570\u5e74\u540e\u53ef\u81ea\u53d1\u6027\u6d88\u9000\u3002<\/p>\n

\u75c5\u7406\u5b66\uff1a<\/p>\n

l\u6dcb\u5df4\u7ed3\u5305\u819c\u589e\u539a\uff0c\u7ea4\u7ef4\u5316\uff1b<\/p>\n

l\u6dcb\u5df4\u7aa6\u663e\u8457\u6269\u5f20\uff0c\u5145\u6ee1\u7279\u5f81\u6027\u7ec4\u7ec7\u7ec6\u80de\uff08\u660e\u533a\uff09\uff0c\u8be5\u7ec4\u7ec7\u7ec6\u80de\u4f53\u79ef\u5927\uff0c\u80de\u6d46\u975e\u5e38\u4e30\u5bcc\u76f4\u5f84\u4e3a\u5c0f\u6dcb\u5df4\u7ec6\u80de\u68386-12\u500d\uff0c\u56e0\u8be5\u7ec4\u7ec7\u7ec6\u80de\u529f\u80fd\u7f3a\u9677\uff0c\u53ef\u89c1\u6dcb\u5df4\u7ec6\u80de\u6e38\u5165\u7ec4\u7ec7\u7ec6\u80de\u4e2d\uff1b<\/p>\n

 <\/p>\n

l\u9ad3\u8d28\u7684\u7d22\u548c\u7aa6\u5185\u5927\u91cf\u6d46\u7ec6\u80de\uff08\u6697\u533a\uff09\uff1b<\/p>\n

l\u7ec4\u7ec7\u7ec6\u80de\uff1aCD163 \u3001CD68 \u3001S-100 \uff0c\u6eb6\u83cc\u9176\uff08Lys\uff09-\/\u5f31 \uff0cCD1\u03b1-\u3001Langerin-\u3001Cd21-\u3001CD35-\u3002<\/p>\n

\u9274\u522b\u8bca\u65ad\uff1a<\/p>\n

\u7ec4\u7ec7\u7ec6\u80de\u8089\u7624\uff08HS\uff09\u3001\u95f4\u53d8\u5927\u7ec6\u80de\u6dcb\u5df4\u7624\uff08ALCL\uff09\u3001\u8f6c\u79fb\u6027\u764c\u3001\u8f6c\u79fb\u6027\u6076\u6027\u9ed1\u8272\u7d20\u7624\u3001\u6717\u683c\u6c49\u65af\u7ec4\u7ec7\u7ec6\u80de\u589e\u751f\u75c7\uff08LCH\uff09\u3002<\/p>\n

\u4f20\u67d3\u6027\u5355\u6838\u7ec6\u80de\u589e\u751f\u75c7\uff08IM\uff09<\/h2>\n

\u9752\u5c11\u5e74\u6700\u5e38\u89c1\uff1b\u7531EBV\u611f\u67d3\u540e\u51fa\u73b0\u53d1\u70ed\u3001\u54bd\u75db\u3001\u6dcb\u5df4\u7ed3\u80bf\u5927\uff0c\u6241\u6843\u4f53\u589e\u5927\u548c\u813e\u80bf\u5927\uff0850%\uff09\uff1b\u767d\u7ec6\u80de\u589e\u9ad8\uff0812-25\u00d7\/L\uff09\u3001\u6dcb\u5df4\u7ec6\u80de\u536060%\uff0c\u975e\u5178\u578b\u6dcb\u5df4\u7ec6\u80de\u536010%-20%\uff0895%\u4e3aT\u7ec6\u80de\uff09\uff1b\u8840\u6e05monospot\u8bd5\u9a8c \uff0cEBV\u6297\u4f53 \u3002<\/p>\n

 <\/p>\n

\u75c5\u7406\u5b66\uff1a<\/p>\n

\u75c5\u53d8\u65e9\u671f\uff0c\u5355\u6838\u7ec6\u80de\u6837B\u7ec6\u80de\u589e\u751f\u4f34\u53cd\u5e94\u6027\u6ee4\u6ce1\u7ec6\u80de\u589e\u751f\uff0c\u6dcb\u5df4\u7aa6\u5b58\u5728\uff1b\u7ee7\u4e4b\u514d\u75ab\u6bcd\u7ec6\u80de\u3001\u6d46\u6bcd\u7ec6\u80de\u548c\u6d46\u7ec6\u80de\u5f25\u6f2b\u589e\u751f\uff0c\u6b63\u5e38\u7ed3\u6784\u4e0d\u6613\u8fa8\u8ba4\uff1b\u589e\u751f\u7ec6\u80deCD20 \uff0c\u4f46\u9633\u6027\u5f3a\u5ea6\u4e0d\u4e00\uff08\u56e0\u4e00\u7cfb\u5217\u4e0d\u540c\u65f6\u671f\u7684B\u7ec6\u80de\u589e\u751f\uff0c\u6545\u51fa\u73b0\u8868\u8fbe\u5f3a\u5f31\u4e0d\u4e00\uff09\uff0cCD30 \u3001LMP1 \u3001EBER \u3002<\/p>\n

 <\/p>\n

\u9274\u522b\u8bca\u65ad\uff1a<\/p>\n

\u5f25\u6f2b\u5927B\u7ec6\u80de\u6dcb\u5df4\u7624\uff08DLBCL\uff09\u3001\u95f4\u53d8\u5927\u7ec6\u80de\u6dcb\u5df4\u7624\uff08ALCL\uff09\u3001\u970d\u5947\u91d1\u6dcb\u5df4\u7624\uff08HL\uff09\u3001\u836f\u7269\u8bf1\u5bfc\u6027\u6dcb\u5df4\u7ed3\u708e\u3001\u5de8\u7ec6\u80de\u5305\u6db5\u4f53\u75c5\u6bd2\u611f\u67d3\uff08CMV\uff09\u548cHHV-6\u611f\u67d3\u3002<\/p>\n

Kikuchi\u75c5<\/h2>\n

\u5e74\u8f7b\u5973\u6027\uff08\u5e73\u5747\u5e74\u9f8425.5\u5c81\uff09\uff0c\u591a\u89c1\u4e9a\u6d32\u4eba\uff1b\u6dcb\u5df4\u7ed3\u80bf\u5927\uff08\u5c24\u5176\u9888\u90e8\u6dcb\u5df4\u7ed3\uff09\uff0c\u5355\u4e2a\uff0c\u5076\u591a\u4e2a\uff0c\u6700\u5927\u76f4\u5f84<2cm\uff1b\u5e38\u4f34\u53d1\u70ed\u548c\u89e6\u75db\uff1b1-4\u4e2a\u6708\u5185\u81ea\u884c\u6d88\u9000\uff0c\u5076\u53ef\u590d\u53d1\uff08<4%)\u9884\u540e\u826f\u597d\u3002<\/p>\n

1.\u589e\u751f\u671f\uff1aRFH\/RPH\u80cc\u666f\u4e0a\u591a\u4e2a\u4e92\u76f8\u4e0d\u76f8\u8fde\u7684\u6591\u7247\u72b6\u53d7\u7d2f\u533a\uff0c\u7531\u589e\u751f\u6dcb\u5df4\u7ec6\u80de\u3001\u7ec4\u7ec7\u7ec6\u80de\u548c\u6d46\u7ec6\u80de\u6837\u6811\u7a81\u7ec6\u80de\u7ec4\u6210\uff1b\u6dcb\u5df4\u7ec6\u80de\u4e3aCD3 \u3001CD4 \u7684T\u7ec6\u80de\uff1b\u7ec4\u7ec7\u7ec6\u80de\u80de\u6d46\u4e30\u5bcc\uff0c\u5e38\u541e\u566c\u7ec6\u80de\u788e\u5c51\u3001\u6838\u5448\u65b0\u6708\u5f62\u3001\u626d\u66f2\u6216\u5370\u6212\u6837\uff0cCD68 \u3001MPO \uff08\u9700\u8981\u4e0e\u9ad3\u7cfb\u8089\u7624\u9274\u522b\uff09\uff1b\u6d46\u7ec6\u80de\u6837\u6811\u7a81\u7ec6\u80de\u80de\u6d46\u4e2d\u7b49\u91cf\uff0cCD123 \uff1b\u5355\u4e2a\u7ec6\u80de\u574f\u6b7b\uff0c\u6838\u788e\u5c51\uff1b\u7f3a\u4e4f\u4e2d\u6027\u7c92\u7ec6\u80de\u3002<\/p>\n

 <\/p>\n<\/p>\n

2.\u574f\u6b7b\u671f\uff1a\u6591\u7247\u72b6\u53d7\u7d2f\u533a\u53ef\u878d\u5408\u6210\u4e0d\u89c4\u5219\u5730\u56fe\u72b6\u574f\u6b7b\uff1b\u4e2d\u592e\u574f\u6b7b\u533a\u55dc\u4f0a\u7ea2\u51dd\u56fa\u6027\u574f\u6b7b\uff0c\u6df7\u6709\u8bb8\u591a\u7ec4\u7ec7\u7ec6\u80de\u548c\u6838\u788e\u5c51\uff1b\u5468\u56f4\u4e3a\u7ec4\u7ec7\u7ec6\u80de\u548c\u6dcb\u5df4\u7ec6\u80de\uff08CD3 \u3001CD8 \uff09\uff1b\u5916\u5c42\u4e3a\u6dcb\u5df4\u7ec6\u80de\u548c\u514d\u75ab\u7ec6\u80de\u3002<\/p>\n

 <\/p>\n

3.\u6d88\u9000\u671f\uff1a\u574f\u6b7b\u7076\u88ab\u7ea4\u7ef4\u548c\u8089\u82bd\u7ec4\u7ec7\u66ff\u4ee3\uff0c\u51fa\u73b0\u5927\u91cf\u6ce1\u6cab\u72b6\u7ec4\u7ec7\u7ec6\u80de\u3002<\/p>\n

\u9274\u522b\u8bca\u65ad\uff1a<\/p>\n

\u5f25\u6f2b\u5927B\u7ec6\u80de\u6dcb\u5df4\u7624\uff08DLBCL\uff09\u3001T\u7ec6\u80de\u6dcb\u5df4\u7624\uff08PTCL\uff09\u3001\u7cfb\u7edf\u6027\u7ea2\u6591\u72fc\u75ae\uff08SLE\uff09\u3001Kawasaki\u75c5\u3002<\/p>\n

\u7cfb\u7edf\u6027\u7ea2\u6591\u72fc\u75ae\uff08SLE\uff09<\/h2>\n

SLE\u4e3a\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\uff1b<\/p>\n

\u4e34\u5e8a\u8868\u73b0\uff1a\u988a\u75b9\u3001\u76d8\u5f62\u75b9\u3001\u5149\u8fc7\u654f\uff1b\u53e3\u8154\u6e83\u75a1\u3001\u5173\u8282\u708e\u3001\u6d46\u819c\u708e\u3001\u80be\u529f\u80fd\u5f02\u5e38\u3001\u795e\u7ecf\u7cfb\u7edf\u75be\u75c5\u3001\u8840\u6db2\u5b66\u6539\u53d8\u3001\u514d\u75ab\u5f02\u5e38\u548c\u6297\u6838\u6297\u4f53\uff1b<\/p>\n

\u75c5\u7406\u5b66\uff1a\u540cKikuchi\u75c5\uff0c\u4f46\u53ef\u89c1\u82cf\u6728\u7d20\u5c0f\u4f53\uff08HB\uff09\uff0c\u4e3a10um\u7684\u5747\u4e00\u7d2b\u8272\u5c0f\u4f53\uff0c\u5206\u5e03\u4e8e\u574f\u6b7b\u7076\u5185\u6216\u9644\u8fd1\u3002\u6b64\u5916\uff0c\u5982\u5b58\u5728\u5927\u91cf\u6d46\u7ec6\u80de\u3001\u660e\u663eRFH\u3001\u8840\u7ba1\u708e\u3001\u5305\u819c\u6216\u5305\u819c\u5468\u56f4\u708e\uff0c\u5e94\u7591\u4e3aSLE\u3002<\/p>\n

 <\/p>\n

Kawasaki\u75c5<\/h2>\n

\u53c8\u79f0\u4e3a\u9ecf\u819c\u76ae\u80a4\u6dcb\u5df4\u7ed3\u7efc\u5408\u5f81\uff1b\u4e3b\u8981\u7d2f\u53ca5\u5c81\u4ee5\u4e0b\u4e9a\u6d32\u513f\u7ae5\u7684\u7f55\u89c1\u6027\u75be\u75c5\uff1b\u4e34\u5e8a\u4e0a\u5206\u4e8c\u671f\uff1a\u7b2c\u4e00\u671f\uff1a\u9ad8\u70ed\u81f3\u5c11\u6301\u7eed5\u5929\u4ee5\u4e0a\uff1b\u773c\u7ed3\u819c\u708e\uff1b\u76ae\u75b9\uff1b\u56db\u80a2\u8fdc\u7aef\u75c5\u53d8\uff1b\u53e3\u8154\u7c98\u819c\u708e\u548c\u6dcb\u5df4\u7ed3\u80bf\u5927\u3002<\/p>\n

\u7b2c\u4e8c\u671f\uff1a\u8131\u76ae\uff0c\u5c24\u5176\u624b\u548c\u8db3\uff1b\u5173\u8282\u75db\uff1b\u8179\u6cfb\u3001\u5455\u5410\u6216\u8179\u75db\uff1b<\/p>\n

\u5982\u4e0d\u6cbb\u53ef\u53d1\u751f\u8840\u7ba1\u708e\uff0c\u5a01\u80c1\u751f\u547d\uff0c\u9759\u8109\u5185\u6ce8\u5c04r\u7403\u86cb\u767d\u548c\/\u6216\u9ad8\u5242\u91cf\u963f\u53f8\u5339\u6797\u53ef\u6cbb\u6108\u3002<\/p>\n

\u75c5\u7406\u5b66\uff1a\u5730\u56fe\u6837\u7ea4\u7ef4\u7d20\u574f\u6b7b\u3001\u6838\u788e\u7247\u3001\u4f34\u4e2d\u6027\u7c92\u7ec6\u80de\u6d78\u6da6\u7ea4\u7ef4\u7d20\u6027\u8840\u6813\uff0c\u5e38\u8d85\u51fa\u574f\u6b7b\u533a\uff0c\u52a8\u8109\u708e\u3002<\/p>\n<\/p>\n

\u732b\u6293\u75c5\uff08CSD\uff09<\/h2>\n

\u6c49\u585e\u5df4\u5c14\u901a\u4f53\u5f15\u8d77\u7684\u611f\u67d3\u6027\u75be\u75c5\uff1b\u597d\u53d1\u751f\u4e8e\u513f\u7ae5\u548c\u9752\u5c11\u5e74\uff1b<\/p>\n

\u732b\u6216\u5176\u4ed6\u5c0f\u52a8\u7269\u6293\u4f24\u6216\u54ac\u4f24\u75c5\u53f2\uff1b\u76ae\u80a4\u51fa\u73b0\u7ea2\u6591\u3001\u4e18\u75b9\u3001\u6c34\u75b1\u3001\u7ed3\u75c2\uff1b1-3\u5468\u540e\u6dcb\u5df4\u7ed3\u80bf\u5927\u3002<\/p>\n

\u6dcb\u5df4\u7aa6\u548c\u6ee4\u6ce1\u95f4\u533a\u5927\u91cf\u5355\u6838\u7ec6\u80de\u6837B\u7ec6\u80de\u589e\u751f\uff0c\u6563\u5728\u4e2d\u6027\u7c92\u7ec6\u80de\u548c\u7ec4\u7ec7\u7ec6\u80de\uff1b\u5316\u8113\u6027\u8089\u82bd\u80bf\u76f8\u4e92\u878d\u5408\u6210\u4e0d\u89c4\u5219\u5f62\u548c\u661f\u5f62\uff0c\u4e2d\u592e\u4e3a\u4e2d\u6027\u7c92\u7ec6\u80de\u788e\u5c51\u548c\u7ea4\u7ef4\u7d20\u6837\u6027\u574f\u6b7b\uff0c\u5468\u8fb9\u4e3a\u6805\u680f\u6392\u5217\u7684\u7ec4\u7ec7\u7ec6\u80de\uff1b\u591a\u6838\u5de8\u7ec6\u80de\u5c11\u6216\u65e0\uff1b\u6d46\u7ec6\u80de\u548c\u514d\u75ab\u6bcd\u7ec6\u80de\u589e\u751f\u3002<\/p>\n

\u9274\u522b\u8bca\u65ad\uff1a\u7ed3\u8282\u786c\u5316\u6027\u970d\u5947\u91d1\u6dcb\u5df4\u7624\uff08NSCHL\uff09\u3001\u7ed3\u6027\u75c5\u8089\u82bd\u80bf\u3001\u8036\u5c14\u68ee\u83cc\u611f\u67d3\u3002<\/p>\n<\/p>\n

\u76ae\u80a4\u75c5\u6027\u6dcb\u5df4\u7ed3\u708e\uff08DL\uff09<\/h2>\n

\u76ae\u80a4\u7684\u826f\u6027\u6216\u6076\u6027\u75c5\u53d8\u5f15\u8d77\u7684\u5f15\u6d41\u533a\u6dcb\u5df4\u7ed3\u80bf\u5927\uff1b\u6210\u5e74\u7537\u6027\uff0c\u7537\u5973\u6bd4\u4f8b2:1\uff1b\u76ae\u80a4\u7619\u75d2\uff0c\u6dcb\u5df4\u7ed3\u80bf\u5927\uff0c\u5c24\u5176\u662f\u814b\u7a9d\u6dcb\u5df4\u7ed3\u548c\u8179\u80a1\u6c9f\u6dcb\u5df4\u7ed3\uff0c\u90e8\u5206\u60a3\u8005\u5468\u56f4\u8840\u4e2d\u55dc\u9178\u6027\u7c92\u7ec6\u80de\u589e\u591a\u3002<\/p>\n

\u75c5\u7406\u5b66\uff1a<\/p>\n

\u6dcb\u5df4\u7ed3\u8f7b-\u4e2d\u5ea6\u589e\u5927\uff0c\u8d28\u575a\u5b9e\uff0c\u5207\u9762\u7070\u9ec4\u81f3\u6d45\u68d5\u8272\uff0c\u53ef\u6709\u9ed1\u8272\u6761\u7eb9\uff0c\u4f4e\u500d\u955c\u4e0b\u6dcb\u5df4\u526f\u76ae\u8d28\u533a\u663e\u8457\u6269\u5927\uff0c\u8868\u73b0\u4e3a\u7ed3\u8282\u6027\u3001\u4e0d\u89c4\u5219\u6216\u5f25\u6f2b\u6027\u611f\u67d3\u533a\uff1b\u589e\u751f\u7684\u7ec6\u80de\u7531\u4ea4\u6307\u6811\u7a81\u7ec6\u80de\uff08IDC\u589e\u751f\u4e3a\u4e3b\uff09\u3001Langerhans\u7ec6\u80de\uff08LC\uff09\u548c\u7ec4\u7ec7\u7ec6\u80de\uff08HC\uff09\u7ec4\u6210\uff1b<\/p>\n

**IDC\uff1as-100 \u3001CD1\u03b1-\u3001Langerin-\uff1bLC\uff1as-100 \u3001CD1\u03b1 \u3001Langerin \uff1bHC\uff1aCD163 \u3001CD68 \u3001Lys \u3002<\/p>\n<\/p>\n

\u75c5\u53d8\u5185\u6dcb\u5df4\u7ec6\u80de\u5927\u591a\u4e3aCD3 \u3001CD4 \u8f85\u52a9T\u7ec6\u80de\uff0c\u6709\u4e9bT\u7ec6\u80deCD7-\uff1b\u65e0\u8bba\u826f\u6076\u6027\u76ae\u80a4\u75c5\u7684\u6dcb\u5df4\u7ed3\u5185\u90fd\u53ef\u6709\u4e00\u4e9b\u6563\u5728\u7684\uff0c\u6838\u5448\u8111\u56de\u72b6\u7684\u5c0f\u6dcb\u5df4\u7ec6\u80de\uff1b\u5f53\u8111\u56de\u72b6\u5c0f\u6dcb\u5df4\u7ec6\u80de\u51fa\u73b0\u975e\u5178\u578b\u6027\u548c\u6838\u5206\u88c2\u8c61\uff0c\u5448\u7c07\u72b6\u6216\u7247\u72b6\u5206\u5e03\u65f6\uff0c\u5e94\u8003\u8651\u4e3aMF\/SS\u7d2f\u53ca\u6dcb\u5df4\u7ed3\u3002<\/p>\n

\u81ea\u8eab\u514d\u75ab\u6dcb\u5df4\u7ec6\u80de\u589e\u751f\u6027\u7efc\u5408\u5f81\uff08ALPS\uff09<\/h2>\n

\u5927\u591a\u6570\u7531Fas\u3001FasL\u6216caspase\u57fa\u56e0\u80da\u7cfb\u7a81\u53d8\uff0c\u5c11\u6570\u7531Fas\u57fa\u56e0\u4f53\u7ec6\u80de\u6742\u5408\u6027\u7a81\u53d8\u5f15\u8d77\u6dcb\u5df4\u7ec6\u80de\u51cb\u4ea1\u53d7\u963b\uff0c\u5bfc\u81f4\u6dcb\u5df4\u7ec6\u80de\u589e\u591a\u3001\u5168\u8eab\u6dcb\u5df4\u7ed3\u80bf\u5927\u3001\u809d\u80bf\u5927\u3001\u9ad8r\u7403\u86cb\u767d\u8840\u75c7\u548c\u81ea\u8eab\u514d\u75ab\u73b0\u8c61\u3002<\/p>\n

\u597d\u53d1\u4e8e\u513f\u7ae5\u548c\u5e74\u8f7b\u4eba\uff0c\u5168\u8eab\u6dcb\u5df4\u7ed3\u80bf\u5927\uff0c\u81ea\u8eab\u6297\u4f53\u9633\u6027\u53cd\u5e94\uff0c\u5faa\u73af\u4e2dCD4-\u3001CD8-T\u7ec6\u80de\u589e\u52a0\uff0c\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u3002<\/p>\n

\u75c5\u7406\u5b66\uff1a<\/p>\n

\u6dcb\u5df4\u7ed3\u526f\u76ae\u8d28\u533a\u9ad8\u5ea6\u589e\u751f\uff0c\u589e\u751f\u7684\u7ec6\u80de\u7531\u514d\u75ab\u6bcd\u7ec6\u80de\u3001\u6d46\u7ec6\u80de\u548c\u4e2d\u7b49\u5927\u7684\u900f\u660e\u7ec6\u80de\u7ec4\u6210\uff1b\u589e\u751f\u7684\u7ec6\u80de\u4e3aCD3 \u3001D4-\u3001CD8-\u3001CD45RO-\u3001CD57 \u7684T\u7ec6\u80de\uff0cTIA1 \u3001perforin \uff1b\u6d46\u7ec6\u80de\u4e3a\u591a\u514b\u9686\u6027\u3002<\/p>\n<\/p>\n

\u75c5\u7406\u89c6\u9891\u8d44\u6599\u56e0\u4e3a\u7a00\u5c11\uff0c\u6240\u4ee5\u5b9d\u8d35\uff0c\u5c0f\u7f16\u4e5f\u5728\u641c\u7f57\u5404\u79cd\u75c5\u7406\u89c6\u9891\u8d44\u6e90\uff0c\u6709\u60f3\u6cd5\u7684\u5b9d\u5b50\u4eec\u53ef\u4ee5\u52a0\u5165\u3010\u75c5\u7406\u79d1\u6843\u5b50\u89c6\u9891\u8d44\u6599\u3011\u7fa4\uff0c\u628a\u7a00\u7f3a\u7684\u89c6\u9891\u8d44\u6e90\u9886\u56de\u5bb6\u5427\uff01\u8d44\u6599\u4f1a\u4e0d\u5b9a\u671f\u66f4\u65b0\u5594\uff5e\uff5e\uff5e<\/p><\/p>\n","protected":false},"excerpt":{"rendered":"

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