{"id":31412,"date":"2024-04-26T00:00:53","date_gmt":"2024-04-26T00:00:53","guid":{"rendered":"https:\/\/zydq.1006ss.com\/?p=31412"},"modified":"2024-04-26T00:00:53","modified_gmt":"2024-04-26T00:00:53","slug":"5-3%e3%80%80%e7%bb%b4%e7%94%9f%e7%b4%a0d","status":"publish","type":"post","link":"http:\/\/zydq.1006ss.com\/?p=31412","title":{"rendered":"5.3\u3000\u7ef4\u751f\u7d20D"},"content":{"rendered":"<p>                <b>5.3.1\u3000\u7ed3\u6784\u4e0e\u6027\u8d28<\/b><\/p>\n<p>\u7ef4\u751f\u7d20D\uff08VD\uff09\u662f\u73af\u620a\u70f7\u591a\u6c22\u83f2\u7c7b\u5316\u5408\u7269\uff0c\u53ef\u7531\u7ef4\u751f\u7d20D\u539f\uff08ProvitaminD\uff09\u7ecf\u7d2b\u5916\u7ebf270~300nm\u6fc0\u6d3b\u5f62\u6210\u3002\u52a8\u7269\u76ae\u4e0b7-\u8131\u6c22\u80c6\u56fa\u9187\uff0c\u9175\u6bcd\u7ec6\u80de\u4e2d\u7684\u9ea6\u89d2\u56fa\u9187\u90fd\u662f\u7ef4\u751f\u7d20D\u539f\uff0c\u7ecf\u7d2b\u5916\u7ebf\u6fc0\u6d3b\u5206\u522b\u8f6c\u5316\u4e3a\u7ef4\u751f\u7d20D<sub>3<\/sub>\u53ca\u7ef4\u751f\u7d20D<sub>2<\/sub>\u91cf\u5c11\uff0c\u4f46\u4eba\u5de5\u7167\u5c04\u8005\u591a\u4e3a\u6b64\u578b\uff08\u56fe5-6\uff09\u3002\u7ef4\u751f\u7d20D\u7684\u6700\u5927\u5438\u6536\u5cf0\u4e3a265nm\uff0c\u6bd4\u8f83\u7a33\u5b9a\uff0c\u6eb6\u89e3\u4e8e\u6709\u673a\u6eb6\u5a92\u4e2d\uff0c\u5149\u4e0e\u9178\u4fc3\u8fdb\u5f02\u6784\u4f5c\u7528\uff0c\u5e94\u50a8\u5b58\u5728\u6c2e\u6c14\u3001\u65e0\u5149\u4e0e\u65e0\u9178\u7684\u51b7\u73af\u5883\u4e2d\uff0c\u6cb9\u6eb6\u6db2\u52a0\u6297\u6c27\u5316\u5242\u540e\u7a33\u5b9a\uff0c\u6c34\u6eb6\u6db2\u7531\u4e8e\u6709\u6eb6\u89e3\u7684\u6c27\u4e0d\u7a33\u5b9a\u3002\u53cc\u952e\u7cfb\u7edf\u8fd8\u539f\u4e5f\u53ef\u635f\u5931\u5176\u751f\u7269\u6548\u7528\u3002<\/p>\n<\/p>\n<p>\u56fe5-6 \u9ea6\u89e3\u56fa\u9187\u53ca7-\u8131\u6c22\u57fa\u80c6\u56fa\u9187\u5728\u7d2b\u5916\u7ebf\u4f5c\u7528\u4e0b\u8f6c\u53d8\u4e3a\u7ef4\u751f\u7d20D<sub>2<\/sub>\u53ca\u7ef4\u751f\u7d20D<sub>3<\/sub><\/p>\n<p><b>5.3.2\u3000\u4ee3\u8c22<\/b><\/p>\n<p>\u4ece\u98df\u7269\u4e2d\u5f97\u6765\u7684\u7ef4\u751f\u7d20D\uff0c\u4e0e\u8102\u80aa\u4e00\u8d77\u5438\u6536\uff0c\u5438\u6536\u90e8\u4f4d\u4e3b\u8981\u5728\u7a7a\u80a0\u4e0e\u56de\u80a0\u3002\u80c6\u6c41\u5e2e\u52a9\u5176\u5438\u6536\u3002\u8102\u80aa\u5438\u6536\u53d7\u5e72\u6270\u65f6\uff0c\u5982\u6162\u6027\u80f0\u817a\u708e\u3001\u8102\u80aa\u75e2\u53ca\u80c6\u9053\u963b\u585e\u90fd\u4f1a\u5f71\u54cd\u4ed6\u7684\u5438\u6536\u3002\u5438\u6536\u7684\u7ef4\u751f\u7d20D\u4e0e\u4e73\u7cdc\u5fae\u7c92\u76f8\u7ed3\u5408\uff0c\u7531\u6dcb\u5df4\u7cfb\u7edf\u8fd0\u8f93\uff0c\u4f46\u4e5f\u53ef\u4e0e\u7ef4\u751f\u7d20D\u8fd0\u8f93\u86cb\u767d\uff08\u03b1-\u7403\u86cb\u767d\u90e8\u5206\uff09\u76f8\u7ed3\u5408\u5728\u8840\u6d46\u4e2d\u8fd0\u8f93\u3002\u6709\u4e9b\u4e0e\u03b2-\u8102\u86cb\u767d\u76f8\u7ed3\u5408\uff0c\u53e3\u670d\u7ef4\u751f\u7d20D\u4e0e\u4e73\u7cdc\u5fae\u7c92\u7ed3\u5408\uff0c\u6bd4\u4ece\u76ae\u80a4\u4e2d\u6765\u7684\u4e0e\u86cb\u767d\u7ed3\u5408\u8005\u6613\u4e8e\u5206\u89e3\u3002<\/p>\n<p>\u5f53\u7ef4\u751f\u7d20D\u8fd0\u5230\u809d\u810f\u4e2d\uff0c\u5728\u5fae\u7c92\u4f53\u4e2d\u7ecf\u5355\u6c27\u9176\u7cfb\u7edf\u4f5c\u7528\uff0c\u5c06\u517625\u4f4d\u7f9f\u57fa\u5316\u5f62\u621025\uff08OH\uff09D(25-hydroxy vitamin D<sub>3<\/sub>)(\u56fe5-7)\uff0c\u809d\u5916\u7684\u5176\u4ed6\u7ec4\u7ec7\u4e5f\u53ef\u5438\u53d6\u7ef4\u751f\u7d20D\u53ca25-\uff08OH\uff09D<sub>3<\/sub>\uff0c\u56e0\u6b64\u7ec4\u7ec7\u4e2d\u7ef4\u751f\u7d20D\u53ca25\uff08OH\uff09D<sub>3<\/sub>\u53ca\u5176\u603b\u91cf\u6bd4\u8840\u6d46\u4e2d\u591a\uff0c\u5982\u679c\u9776\u7ec4\u7ec7\u9700\u8981\uff0c\u53ef\u5c06\u5176\u91ca\u653e\u51fa\u6765\uff0c\u4ed6\u4eec\u5728\u8102\u80aa\u7ec4\u7ec7\u4e2d\u6700\u591a\uff0c\u91ca\u653e\u901f\u5ea6\u6700\u6162\uff0c\u5f53\u4f53\u91cd\u51cf\u8f7b\uff0c\u8102\u80aa\u51cf\u5c11\u65f6\uff0c\u4ed6\u4eec\u4e5f\u53ef\u91ca\u653e\u51fa\u6765\u3002\u9759\u8109\u6ce8\u5c04\u7ef4\u751f\u7d20D\uff0c\u8f83\u5feb\u7684\u7531\u8840\u6d46\u8fdb\u5165\u5230\u7ec4\u7ec7\u4e2d\u3002\u8840\u6d46\u4e2d25\uff08OH\uff09D<sub>3<\/sub>\u5728\u6ce8\u5c04\u540e1\uff5e3\u5929\u8fbe\u5230\u9ad8\u5cf0\uff0c\u5176\u6d53\u5ea6\u53ef\u8fbe\u523020\uff5e40ng\u00b7ml<sup>-1<\/sup>,\u6700\u9ad8\u53ef\u8fbe80ng\u00b7ml<sup>-1<\/sup>\u3002\u6d53\u5ea6\u4e0e\u6444\u5165\u91cf\u6709\u4e00\u5b9a\u7684\u5173\u7cfb\uff0c\u5c0f\u4e8e4 ng\u00b7ml<sup>-1<\/sup>,\u4e34\u5e8a\u4e0a\u53ef\u53d1\u751f\u4f5d\u507b\u75c5\u53ca\u9aa8\u8d28\u8f6f\u5316\u300225\uff08OH\uff09D<sub>3<\/sub>\u5728\u80be\u7ebf\u7c92\u4f53\u5355\u6c27\u9176\u4f5c\u7528\u4e0b\uff08\u9176\u7cfb\u7edf\u5305\u62ec\u7ec6\u80de\u8272\u7d20P<sub>450<\/sub>\u3001\u94c1\u786b\u86cb\u767d\u53ca\u9ec4\u7d20\u86cb\u767d\uff09\uff0c\u7ecf\u7fa7\u57fa\u5316\uff0c\u8f6c\u53d8\u4e3a1\uff0c25\uff08OH\uff09<sub>2<\/sub>D<sub>3<\/sub>(1,25-dihydroxy vxtamin D),\u4ed6\u662f\u7ef4\u751f\u7d20D\u7684\u751f\u7269\u4f5c\u7528\u5f62\u5f0f\uff0c\u73b0\u5c06\u5176\u4f5c\u4e3a\u6fc0\u7d20\u3002\u5176\u4f5c\u7528\u65b9\u5f0f\u4e0e\u5176\u4ed6\u56fa\u9187\u7c7b\u6fc0\u7d20\u76f8\u4f3c\u3002\u5728\u9776\u7ec4\u7ec7\u4e2d\u90fd\u6709\u5176\u53d7\u4f53\uff0c1\uff0c25\uff08OH\uff09<sub>2<\/sub>D<sub>3<\/sub>\u4e0e\u53d7\u4f53\u5f62\u6210\u590d\u5408\u7269\u5185\uff0c\u4e0e\u7ec6\u80de\u6838\u6216\u67d3\u8272\u4f53\u76f8\u7ed3\u5408\uff0c\u901a\u8fc7DNA\u8f6c\u5f55\u4f5c\u7528\u5408\u6210\u4fe1\u4f7fRNA\uff08mRNA\uff09\uff0c\u5e76\u8f6c\u8bd1\u4e3a\u86cb\u767d\u8d28\uff0c1\uff0c25\uff08OH\uff09<sub>2<\/sub>D<sub>3<\/sub>\u5728\u8840\u6d46\u4e2d\u7531\u5206\u5b50\u91cf\u4e3a52\uff0c00\u7684\u86cb\u767d\u8d28\u8f93\u9001\u81f3\u9776\u7ec4\u7ec7\uff08\u5982\u5c0f\u80a0\u3001\u9aa8\u3001\u80be\u7b49\uff09\uff0c\u5728\u8fd9\u4e9b\u7ec4\u7ec7\u4e2d\u65e2\u67091\uff0c25\uff08OH\uff09<sub>2<\/sub>D<sub>3<\/sub>\u7684\u53d7\u4f53\uff0c\u53c8\u6709\u9700\u8981VD\u7684\u9499\u7ed3\u5408\u86cb\u767d\uff08Calcium binding Protein,CaBP\uff09,\u8bf4\u660e1\uff0c25\uff08OH\uff09<sub>2<\/sub>D<sub>3<\/sub>\u7684\u5f71\u54cd\u3002\u6700\u8fd1\uff0c\u62a5\u9053\u80f0\u810f\u5185\u67091\uff0c25\uff08OH\uff09<sub>2<\/sub>D<sub>3<\/sub>\u53caCaBP\uff0c\u4e8c\u8005\u5747\u5b58\u5728\u4e8e\u5206\u6ccc\u80f0\u5c9b\u7d20\u7684\u03b2\u7ec6\u80de\u5185\uff0c\u5728\u7ef4\u751f\u7d20D\u7a7a\u7aed\u60c5\u51b5\u4e0b\uff0c\u53ef\u4ee5\u963b\u6b62\u80f0\u5c9b\u7d20\u7684\u5206\u6ccc\uff0c\u4e5f\u6709\u4eba\u8bc1\u660e1\uff0c25\uff08OH\uff09<sub>2<\/sub>D<sub>3<\/sub>\u5bf9\u4e8e\u5e72\u7ec6\u80de\u7684\u751f\u957f\u4e0e\u5206\u5316\u6709\u5173\u3002<\/p>\n<\/p>\n<p>\u56fe5-7 25-\uff08OH\uff09D<sub>3<\/sub>\u53ca1a\uff1b25\uff08OH\uff09<sub>2<\/sub>D<sub>3<\/sub>\u7684\u7ed3\u6784\u5f0f<\/p>\n<p>\u5728\u80be\u4e2d1\u4f4d\u7fa7\u57fa\u5316\u9176\u4e0e24\u4f4d\u7fa7\u57fa\u5316\u9176\u76f8\u6291\u5236\uff0c\u4e3a\u8840\u9499\u6c34\u5e73\u6240\u63a7\u5236\u3002\u5728\u6b63\u5e38\u8840\u9499\u6d53\u5ea6\u4e0b\uff089.5mg%\uff09\u80be\u4e2d1\u03b1\u7fa7\u57fa\u5316\u9176\u4e0e24\u4f4d\u7fa7\u57fa\u5316\u9176\u90fd\u6709\u6d3b\u529b\uff0c\u6240\u4ee5\u65e2\u80fd\u5408\u62101\uff0c25\uff08OH\uff09<sub>2<\/sub>D<sub>3<\/sub>\u4e5f\u80fd\u5408\u621024\uff0c25\uff08OH\uff09<sub>2<\/sub>D<sub>3<\/sub>\uff0c\u8840\u6e05\u9499\u4f4e\u65f6\uff0c\u523a\u6fc01\u4f4d\u7fa7\u57fa\u5316\u9176\uff0c\u9499\u591a\u65f6\u6291\u5236\u6b64\u9176\u3002\u7531\u6b64\u4ee5\u8c03\u82821\uff0c25\uff08OH\uff09<sub>2<\/sub>D<sub>3<\/sub>\u5408\u6210\u4e4b\u91cf\u30021\uff0c25\uff08OH\uff09<sub>2<\/sub>D<sub>3<\/sub>\u5408\u6210\u91cf\u591a\uff0c24\uff0c25\uff08OH\uff09<sub>2<\/sub>D<sub>3<\/sub>\u5408\u6210\u91cf\u5c11\uff0c\u9664\u8840\u9499\u5916\uff0c\u5c1a\u6709\u5176\u4ed6\u56e0\u7d20\u5f71\u54cd1\uff0c25\uff08OH\uff09<sub>2<\/sub>D<sub>3<\/sub>\u5982\u7532\u72b6\u65c1\u817a\u7d20\uff08Parthormone,PTH\uff09\u3001\u964d\u9499\u7d20\uff08Calcitonin,CT\uff09\u3001\u50ac\u4e73\u6fc0\u7d20\u90fd\u53ef\u4f7f\u5176\u589e\u591a\u3002\u80be\u4e3a2\u4e2a\u7fa7\u57fa\u5316\u7684\u4e3b\u8981\u7ec4\u7ec7\uff0c\u4f46\u5728\u4f53\u5916\u8bd5\u9a8c\u5df2\u8bc1\u660e\u9aa8\u3001\u80ce\u76d8\u3001\u80a0\u53ca\u86cb\u9ec4\u5747\u6709\u6b64\u529f\u80fd\u3002<\/p>\n<p>1\uff0c25\uff08OH\uff09<sub>2<\/sub>D<sub>3<\/sub>\u7684\u5206\u89e3\u4ee3\u8c22\u4e0e24\uff0c25\uff08OH\uff09<sub>2<\/sub>D<sub>3<\/sub>\u7684\u9014\u5f84\u76f8\u7c7b\u4f3c\u300224\u4f4d\u7fa7\u57fa\u5316\u540e\u53ef\u8fdb\u4e00\u6b65\u6c27\u5316\u621024\u4f4d\u6c27\u7edc\u7269\uff0c\u7136\u540e23\u4f4d\u7fa7\u57fa\u5316\uff0c\u4fa7\u94fe\u5206\u88c2\u300226-C\uff0c27-C\u53ef\u6c27\u5316CO<sub>2<\/sub>\u6c34\u6eb6\u6027\u4ee3\u8c22\u7269\u6709\u7ef4\u751f\u7d20D<sub>3<\/sub>-23\u7fa7\u9178(Calcitroic acid)\uff0c\u4e5f\u53ef\u4ea7\u751f\u5185\u916f\u53ca\u9178\u916f\uff0c\u7ef4\u751f\u7d20D\u7684\u5206\u89e3\u4ee3\u8c22\u4e3b\u8981\u573a\u6240\u5728\u809d\u5185\uff0c\u5e76\u5c06\u5176\u4ee3\u8c22\u7269\u6392\u5165\u5230\u80c6\u6c41\u4e2d\uff0c\u53e3\u670d\u7ef4\u751f\u7d20D\u6bd4\u4ece\u76ae\u80a4\u4e2d\u5f97\u6765\u7684\u6613\u4e8e\u5206\u89e3\u300225\uff08OH\uff09<sub>2<\/sub>D<sub>3<\/sub>\u53ca1\uff0c25\uff08OH\uff09<sub>2<\/sub>D<sub>3<\/sub>\u4e5f\u53ef\u4ee5\u8461\u7cd6\u82f7\u9178\u5f62\u5f0f\u901a\u8fc7\u80c6\u809d\u5f62\u6210\u809d\u80a0\u5faa\u73af\u6216\u4ece\u5927\u4fbf\u4e2d\u6392\u51fa\u3002\u53e3\u670d\u751f\u7406\u5242\u91cf48h\u540e\uff0c30%\u7684\u5242\u91cf\u4ece\u5927\u4fbf\u4e2d\u6392\u51fa\uff0c\u4ec52-\uff5e4%\u4ece\u5c3f\u4e2d\u6392\u51fa\u3002<\/p>\n<p><b>5.3.3\u3000\u751f\u7406\u529f\u7528<\/b><\/p>\n<p>\uff081\uff09\u7ef4\u6301\u8840\u6e05\u9499\u78f7\u6d53\u5ea6\u7684\u7a33\u5b9a 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1\u4f4d\u7fa7\u57fa\u5316\u9176\u9664\u53d7\u8840\u6e05\u4e2d\u9499\u78f7\u6d53\u5ea6\u53ca\u81b3\u98df\u4e2d\u9499\u78f7\u4f9b\u7ed9\u91cf\u7684\u5f71\u54cd\u5916\uff0c\u8fd8\u53d7\u6fc0 \u7d20\u7684\u5f71\u54cd\uff0c\u505c\u7ecf\u540e\u7684\u5987\u59731\uff0c25\uff08OH\uff09<sub>2<\/sub>D<sub>3<\/sub>\u6d53\u5ea6\u51cf\u4f4e\uff0c\u6613\u6709\u9aa8\u8d28\u8f6f\u5316\u7b49\u75c7\u72b6\u3002<\/p>\n<p>\u5728\u6000\u5b55\u671f\u95f41\uff0c25\uff08OH\uff09<sub>2<\/sub>D<sub>3<\/sub>\u8840\u6d46\u6d53\u5ea6\u4e0a\u5347\uff0c\u54fa\u4e73\u671f\u7ee7\u7eed\u4e0a\u5347\uff0c\u65ad\u4e73\u540e\u6bcd\u4f53\u9010\u6e10\u6062\u590d\u5230\u6b63\u5e38\u6c34\u5e73\u300224\uff0c25\uff08OH\uff09<sub>2<\/sub>D<sub>3<\/sub>\u4e4b\u6c34\u5e73\u4e0e\u4e4b\u76f8\u53cd\uff0c\u6000\u5b55\u671f\u4e0b\u964d\uff0c\u65ad\u4e73\u540e\u6062\u590d\u5230\u6b63\u5e38\u3002\u80ce\u76d8\u4e5f\u67091\u4f4d\u7fa7\u57fa\u5316\u9176\uff0c\u5728\u6000\u5b55\u671f\u95f4\u65e0\u80be\u52a8\u7269\u4e5f\u80fd\u5408\u62101\uff0c25\uff08OH\uff09<sub>2<\/sub>D<sub>3<\/sub>\u3002\u4e73\u817a\u4e5f\u662f1\uff0c25\uff08OH\uff09<sub>2<\/sub>D<sub>3<\/sub>\u7684\u9776\u7ec4\u7ec7\uff0c\u5bf9\u4e73\u4e2d\u9499\u7684\u6c34\u5e73\u76f4\u63a5\u5173\u7cfb\uff0c\u6000\u5b55\u53ca\u54fa\u4e73\u671f\u95f4\u6bcd\u4eb2\u53ef\u4ece\u81ea\u8eab\u7684\u9aa8\u4e2d\u5c06\u9499\u8f93\u51fa\u4ee5\u7ef4\u6301\u80ce\u513f\u5a74\u513f\u6b63\u5e38\u751f\u957f\uff0c\u7ef4\u751f\u7d20D\u4f9b\u5e94\u5145\u8db3\u8005\uff0c\u5728\u65ad\u4e73\u540e\uff0c\u53c8\u53ef\u91cd\u65b0\u83b7\u5f97\u9499\uff0c\u7ef4\u751f\u7d20D\u7f3a\u4e4f\u8005\uff0c\u8fd9\u79cd\u6062\u590d\u80fd\u529b\u8f83\u5dee\u3002<\/p>\n<p>\uff083\uff091\uff0c25\uff08OH\uff09<sub>2<\/sub>D<sub>3<\/sub>\u4f5c\u7528\u673a\u7406 1\uff0c25\uff08OH\uff09<sub>2<\/sub>D<sub>3<\/sub>\u5bf9\u5c0f\u80a0\u4f5c\u7528\u4e3a\u8bf1\u5bfc\u5408\u6210CaBP.1\uff0c25\uff08OH\uff09<sub>2<\/sub>D<sub>3<\/sub>\u4e0e\u5c0f\u80a0\u7ec6\u80de\u7684\u53d7\u4f53\u5f62\u6210\u590d\u5408\u4f53\u8fdb\u5165\u7ec6\u80de\u6838\u67d3\u8272\u4f53\u4e0a\uff0c\u4fc3\u4f7fCaBP\u7684\u4fe1\u4f7fRNA(mRNA)\u7684\u5408\u6210\uff0c\u6b64mRNA\u5728\u80de\u6d46\u5185\u8f6c\u5f55\u4e3aCaBP\u3002\u8fd9\u79cd\u86cb\u767d\u4fc3\u4f7f\u9499\u79bb\u5b50\u901a\u8fc7\u5fae\u7ed2\u6bdb\u5237\u72b6\u7f18\uff08microvillus brush border\uff09\uff0c\u79ef\u7d2f\u4e8e\u80a0\u7ec6\u80de\u7684\u7ebf\u7c92\u4f53\u6216\u5176\u4ed6\u90e8\u4f4d\u3002\u901a\u8fc7Na<sup>+<\/sup>\u5c06Ca<sup>2+<\/sup>\u6324\u51fa\u57fa\u5e95-\u5916\u4fa7\u819c\u5916(basal-lataaral mebrace)\u30021\uff0c25\uff08OH\uff09<sub>2<\/sub>D<sub>3<\/sub>\u5bf9\u80be\u5c0f\u7ba1Ca<sup>2+<\/sup>\u7684\u518d\u5438\u6536\u4f5c\u7528\u4e0e\u5728\u5c0f\u80a0\u4e2d\u662f\u4e00\u6837\u7684\u30021\uff0c25\uff08OH\uff09<sub>2<\/sub>D<sub>3<\/sub>\u4e5f\u53ef\u4ee5\u5728\u4f4e\u8840\u6d46\u9499\u53ca\u81b3\u98df\u4e2d\u9499\u7f3a\u4e4f\u65f6\uff0c\u5c06\u9499\u4ece\u9aa8\u4e2d\u52a8\u5458\u51fa\u6765\uff0c\u4f46\u5728\u9aa8\u4e2d\u672a\u53d1\u73b0\u6709CaBP,1\uff0c24,25\uff08OH\uff09<sub>2<\/sub>D<sub>3<\/sub>\u53ef\u4ee5\u4fc3\u8fdb\u5c0f\u80a0\u5438\u6536\u9499\uff0c\u4f46\u4e0d\u80fd\u4ece\u9aa8\u4e2d\u5c06\u9499\u52a8\u5458\u51fa\u6765\uff0c\u6240\u4ee51\uff0c25\uff08OH\uff09<sub>2<\/sub>D<sub>3<\/sub>\u5bf9\u9aa8\u7684\u4f5c\u7528\u673a\u7406\u4e0e\u5bf9\u5c0f\u80a0\u8005\u662f\u4e0d\u540c\u7684\uff0c\u4f46\u76ee\u524d\u8fd8\u4e0d\u6e05\u695a\u3002<\/p>\n<p>\u9aa8\u7684\u77ff\u7269\u5316\u4f5c\u7528\u7684\u673a\u7406\u5c1a\u672a\u9610\u660e\uff0c\u8865\u51451\uff0c25\uff08OH\uff09<sub>2<\/sub>D<sub>3<\/sub>\u7ed9\u7f3a\u4e4f\u7ef4\u751f\u7d20D\u7684\u52a8\u7269\u53ca\u4eba\u4f53\uff0c\u90fd\u4e0d\u80fd\u6709\u52a9\u4e8e\u9aa8\u4e2d\u77ff\u7269\u8d28\u7684\u6c89\u79ef\u3002\u52a8\u7269\u4f53\u5185\u867d\u7136\u5206\u79bb\u51fa\u8bb8\u591a\u7ef4\u751f\u7d20D\u4ee3\u8c22\u4ea7\u7269\u4f46\u8fc4\u4eca\u5c1a\u672a\u627e\u51fa\u5bf9\u9aa8\u7684\u77ff\u7269\u5316\u6709\u660e\u663e\u4f5c\u7528\u8005\u3002\u5728\u73b0\u9636\u6bb5\u4e2d\u53ea\u4e86\u89e3\u5230\u7ef4\u751f\u7d20D\u4fc3\u8fdb\u9499\u78f7\u7684\u5438\u6536\uff0c\u53c8\u53ef\u5c06\u9499\u78f7\u4ece\u9aa8\u4e2d\u52a8\u5458\u51fa\u6765\uff0c\u4f7f\u8840\u6d46\u9499\u3001\u78f7\u8fbe\u5230\u6b63\u5e38\u503c\uff0c\u4fc3\u4f7f\u9aa8\u7684\u77ff\u7269\u5316\uff0c\u5e76\u4e0d\u65ad\u66f4\u65b0\u3002<\/p>\n<p><b>5.4.3\u3000\u9700\u8981\u91cf<\/b><\/p>\n<p>\uff081\uff09\u7ef4\u751f\u7d20D\u7684\u8425\u517b\u6307\u6807\u8840\u6e05\u4e2d\u78b1\u6027\u78f7\u9178\u9176\u589e\u52a0\u6bd4\u7ef4\u751f\u7d20D\u7f3a\u4e4f\u7684\u4e34\u5e8a\u75c7\u72b6\u51fa\u73b0\u8981\u65e9\u4e00\u4e9b\uff0c\u4ed6\u7684\u589e\u52a0\u5e45\u5ea6\u4e5f\u4e0e\u7ef4\u751f\u7d20D\u7f3a\u4e4f\u7684\u7a0b\u5e8f\u6709\u5173\uff0c\u4f46\u662f\u4ed6\u662f\u975e\u7279\u5f02\u6027\u7684\uff08\u88685-7\uff09\u3002\u8840\u6e05\u4e2dCa\u4e0eP\u7684\u4e58\u79ef\uff08mg%\uff09,\u6b63\u5e38\u503c\u4e3a36\uff5e40\u3002\u4f5d\u507b\u75c5\u53ca\u9aa8\u8d28\u8f6f\u5316\u60a3\u8005\u7684\u4e58\u79ef\u572830\u4ee5\u4e0b\u3002<\/p>\n<p>\u88685-7 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