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\u8fd1\u65e5\uff0c\u56fd\u9645\u80ba\u764c\u7814\u7a76\u534f\u4f1a\uff08International Association for the Study of Lung Cancer\uff0cIASLC\uff09\u901a\u8fc7\u6570\u5b57\u5207\u7247\u7684\u65b9\u5f0f\u8fdb\u884c\u4e86\u51e0\u8f6e\u7684\u9605\u7247\u5206\u6790\u540e\uff0c\u53d1\u73b0\u75c5\u7406\u533b\u5e08\u5728\u6d4b\u5b9a\u80bf\u7624\u5927\u5c0f\u3001\u786e\u5b9a\u6d78\u6da6\u6027\u80bf\u7624\u5927\u5c0f\u65b9\u9762\u7684\u5e73\u5747\u4e00\u81f4\u6027\u4ec5\u5206\u522b\u4e3a6.9%\u300154%\uff0c\u5373\u4e0d\u540c\u75c5\u7406\u533b\u5e08\u5728\u89e3\u8bfb\u6d78\u6da6\u6027\u75c5\u7076\u7684\u5927\u5c0f\u548c\u4f4d\u7f6e\u65b9\u9762\u5b58\u5728\u8f83\u5927\u5dee\u5f02\u3002\u6839\u636e\u9605\u7247\u5206\u6790\u7ed3\u679c\uff0cIASLC\u4e13\u5bb6\u7ec4\u7ecf\u8ba8\u8bba\u540e\u8ba4\u4e3a\uff1a\u584c\u9677\u7684\u8d34\u58c1\u751f\u957f\u533a\u5185\u5e7f\u6cdb\u4e0a\u76ae\u589e\u751f\uff08extensive epithelial proliferation\uff0cEEP\uff09\u53ef\u80fd\u662f\u4e00\u4e2a\u4e0e\u6d78\u6da6\u6027\u751f\u957f\u6709\u5173\u7684\u7279\u5f81\u3002EEP\u5177\u4f53\u662f\u6307\u817a\u8154\u5185\u4e0a\u76ae\u5448\u591a\u5c42\u751f\u957f\uff0c\u4e00\u822c\u5728\u6570\u4e2a\u80ba\u6ce1\u95f4\u9699\u5185\u3001\u4f34\u9ad8\u7ea7\u522b\u7ec6\u80de\u5b66\u7279\u5f81\u3002\u7531\u4e8eEEP\u4e5f\u662f\u5bfc\u81f4\u75c5\u7406\u533b\u5e08\u5224\u5b9a\u76f8\u5173\u7ed3\u679c\u4e0d\u4e00\u81f4\u7684\u539f\u56e0\u4e4b\u4e00\uff0c\u56e0\u6b64\u8be5\u4e13\u5bb6\u7ec4\u63d0\u51fa\u4e86\u584c\u9677\u548cEEP\u7684\u5b9a\u4e49\u6807\u51c6\u6765\u63d0\u9ad8\u76f8\u5173\u5224\u5b9a\u7684\u4e00\u81f4\u6027\u3002<\/p>\n

\u76ee\u524d\uff0c\u76f8\u5173\u6587\u732e\u5df2\u53d1\u8868\u4e8e\u300aMod Pathol\u300b\u6742\u5fd7\u3002\u8be5\u7814\u7a76\u5b66\u672f\u6027\u8f83\u5f3a\uff0c\u6709\u611f\u5174\u8da3\u7684\u540c\u4ec1\u8bf7\u79fb\u6b65\u539f\u6587\u8be6\u7ec6\u53c2\u8be6\u3002\u6b64\u5904\u6211\u4eec\u4ec5\u9009\u62e9\u5176\u4e2d\u7684\u4ee3\u8868\u6027\u56fe\u8868\u7ffb\u8bd1\u540e\u4e0e\u5927\u5bb6\u5206\u4eab\u3002<\/p>\n

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\u53c2\u8003\u6587\u732e<\/p>\n

[1]Rekhtman N, Ang DC, Riely GJ, et al. KRAS mutations are associated with solid growth pattern and tumor-infiltrating leukocytes in lung adenocarcinoma. Mod Pathol. 2013;26(10):1307-1319. <\/p>\n

doi:10.1038\/modpathol.2013.74<\/p>\n","protected":false},"excerpt":{"rendered":"

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