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of esophagogastric junction\uff0cAEG\uff09\u7684\u53d1\u75c5\u7387\u548c\u6b7b\u4ea1\u7387\u4ecd\u65e7\u9ad8\u5c45\u4e0d\u4e0b<sup>[1-4]<\/sup>\u30022020\u5e74\uff0c\u5168\u56fd\u764c\u75c7\u767b\u8bb0\u62a5\u9053\u4e2d\u80c3\u764c\u65b0\u53d1\u75c5\u4f8b\u548c\u6b7b\u4ea1\u75c5\u4f8b\u6570\u5206\u522b\u4e3a47.9\u4e07\u4eba\u548c37.4\u4e07\u4eba\uff0c\u98df\u7ba1\u764c\u65b0\u53d1\u75c5\u4f8b\u548c\u6b7b\u4ea1\u75c5\u4f8b\u6570\u4e3a32.4\u4e07\u4eba\u548c30.1\u4e07\u4eba<sup>[5]<\/sup>\u30022018\u5e74\u4e00\u9879\u5168\u7403\u80c3\u764c\u548c\u98df\u7ba1\u764c\u767b\u8bb0\u6570\u636e\u7684\u5206\u6790\u53d1\u73b0\uff0c\u4e1c\u4e9a\u5730\u533a\u65b0\u53d1\u8d32\u95e8\u764c\u5728\u5168\u7403\u5360\u6bd4\u9ad8\u8fbe67.1%\uff0c\u76f8\u8f832012\u5e74\u6570\u636e\uff0c\u5448\u73b0\u51fa\u663e\u8457\u589e\u52a0\u7684\u8d8b\u52bf<sup>[3,6]<\/sup>\u3002\u8fd120\u5e74\u6765\uff0cAEG\u7684\u53d1\u75c5\u7387\u5728\u6211\u56fd\u4ea6\u5448\u73b0\u5347\u9ad8\u8d8b\u52bf\uff0c\u8fd9\u4e0e\u897f\u65b9\u53d8\u5316\u8d8b\u52bf\u76f8\u4f3c\uff0c\u5176\u4e2d\u65e9\u671f\u6784\u6210\u6bd4\u4f8b\u59cb\u7ec8&lt;20%<sup>[7-10]<\/sup>\u3002\u56e0\u6b64\uff0c\u5916\u79d1\u533b\u751f\u5728AEG\u4e34\u5e8a\u5b9e\u8df5\u4e2d\u4e00\u76f4\u5728\u79ef\u6781\u63a2\u7d22\u7b5b\u67e5\u3001\u8bca\u65ad\u3001\u5916\u79d1\u6cbb\u7597\u548c\u7efc\u5408\u6cbb\u7597\u9886\u57df\u66f4\u4e3a\u4f18\u5316\u7684\u4e2a\u4f53\u5316\u7cbe\u51c6\u8bca\u7597\u7b56\u7565\u3002<\/p>\n<p>\u5728\u5916\u79d1\u6cbb\u7597\u65b9\u9762\uff0cAEG\u7684\u624b\u672f\u6b65\u9aa4\u4e3b\u8981\u5305\u62ec\u539f\u53d1\u80bf\u7624\u5207\u9664\u3001\u6dcb\u5df4\u7ed3\u6e05\u626b\u3001\u6d88\u5316\u9053\u91cd\u5efa\u53ca\u9884\u671f\u53ef\u6839\u6cbb\u5207\u9664\u65f6\u5fc5\u8981\u7684\u8054\u5408\u810f\u5668\u5207\u9664\u3002\u7531\u4e8eAEG\u89e3\u5256\u90e8\u4f4d\u7684\u7279\u6b8a\u6027\uff0c\u5728\u4e34\u5e8a\u5b9e\u8df5\u5de5\u4f5c\u4e2d\uff0c\u5bf9\u4e8eAEG\u60a3\u8005\u5916\u79d1\u6cbb\u7597\u7684\u5173\u952e\u73af\u8282\u5b58\u5728\u8f83\u591a\u4e89\u8bae\uff0c\u4e14\u5176\u8bca\u7597\u5728\u80f8\u5916\u79d1\u548c\u80c3\u80a0\u5916\u79d1\u4e4b\u95f4\u5b58\u5728\u4e00\u5b9a\u4ea4\u53c9\u91cd\u53e0\u3002\u4e3a\u89c4\u8303\u6211\u56fdAEG\u7684\u5916\u79d1\u6cbb\u7597\uff0c\u56fd\u9645\u98df\u7ba1\u75be\u75c5\u5b66\u4f1a\u4e2d\u56fd\u5206\u4f1a\uff08CSDE\uff09\u98df\u7ba1\u80c3\u7ed3\u5408\u90e8\u75be\u75c5\u8de8\u754c\u8054\u76df\u3001\u4e2d\u56fd\u533b\u5e08\u534f\u4f1a\u5185\u955c\u533b\u5e08\u5206\u4f1a\u8179\u8154\u955c\u5916\u79d1\u4e13\u4e1a\u59d4\u5458\u4f1a\u3001\u4e2d\u56fd\u533b\u5e08\u534f\u4f1a\u5916\u79d1\u533b\u5e08\u5206\u4f1a\u4e0a\u6d88\u5316\u9053\u5916\u79d1\u533b\u5e08\u4e13\u4e1a\u59d4\u5458\u4f1a\u548c\u4e2d\u534e\u533b\u5b66\u4f1a\u80bf\u7624\u5206\u4f1a\u80c3\u80a0\u80bf\u7624\u5b66\u7ec4\u7275\u5934\uff0c\u4e8e2018\u5e74\u8054\u5408\u9881\u5e03\u4e86\u300a\u98df\u7ba1\u80c3\u7ed3\u5408\u90e8\u817a\u764c\u5916\u79d1\u6cbb\u7597\u4e2d\u56fd\u4e13\u5bb6\u5171\u8bc6\uff082018\u7248\uff09\u300b\uff0c\u8be5\u5171\u8bc6\u57fa\u4e8e\u9ad8\u7ea7\u522b\u4e34\u5e8a\u8bc1\u636e\u5728\u56fd\u5185\u9996\u6b21\u5bf9AEG\u7684\u5b9a\u4e49\u3001\u5206\u671f\u3001\u624b\u672f\u5f84\u8def\u3001\u5207\u9664\u65b9\u5f0f\u3001\u6dcb\u5df4\u7ed3\u6e05\u626b\u548c\u56f4\u624b\u672f\u671f\u6cbb\u7597\u7b49\u591a\u4e2a\u5173\u952e\u70b9\u7ed9\u51fa\u76f8\u5173\u5efa\u8bae\u548c\u63a8\u8350\u610f\u89c1\uff1b\u540c\u65f6\u9488\u5bf9\u624b\u672f\u5207\u7f18\u8ddd\u79bb\u3001\u6dcb\u5df4\u7ed3\u6e05\u626b\u8303\u56f4\u3001\u672f\u4e2d\u51b0\u51bb\u6d3b\u68c0\u548cAEG\u624b\u672f\u5207\u9664\u65b9\u5f0f\u8fdb\u884c\u4e86\u8f83\u4e3a\u660e\u786e\u7684\u63a8\u8350\u548c\u89c4\u5b9a<sup>[11]<\/sup>\u3002\u5171\u8bc6\u5728AEG\u5916\u79d1\u6cbb\u7597\u9886\u57df\u5f15\u8d77\u8f83\u5927\u53cd\u54cd\uff0c\u8fdb\u4e00\u6b65\u89c4\u8303\u4e86\u6211\u56fdAEG\u7684\u5916\u79d1\u6cbb\u7597\uff0c\u6210\u4e3a\u56fd\u5185\u540c\u884c\u89c4\u8303\u5316\u5f00\u5c55AEG\u5916\u79d1\u6cbb\u7597\u7684\u6307\u5bfc\u6027\u51c6\u5219\u3002\u8fd15\u5e74\u6765\uff0c\u968f\u7740AEG\u76f8\u5173\u4e34\u5e8a\u7814\u7a76\u7684\u8fdb\u4e00\u6b65\u5f00\u5c55\uff0c\u9488\u5bf9AEG\u4e0b\u7eb5\u9694\u6dcb\u5df4\u7ed3\u6e05\u626b\u3001\u8179\u8154\u955c\u3001\u80f8\u8154\u955c\u5728AEG\u5916\u79d1\u6cbb\u7597\u4e2d\u5e94\u7528\u3001AEG\u6dcb\u5df4\u7ed3\u8f6c\u79fb\u89c4\u5f8b\u53ca\u624b\u672f\u5207\u9664\u6d88\u5316\u9053\u91cd\u5efa\u65b9\u5f0f\u7b49\u5173\u952e\u73af\u8282\uff0c\u4e0d\u65ad\u6709\u65b0\u7684\u4e34\u5e8a\u8bc1\u636e\u4ea7\u751f\u3002\u300a\u65e5\u672c\u80c3\u764c\u6cbb\u7597\u6307\u5357\u300b\u548c\u300a\u7f8e\u56fdNCCN\u98df\u7ba1\u764c\u548c\u98df\u7ba1\u80c3\u7ed3\u5408\u90e8\u764c\u4e34\u5e8a\u51b3\u7b56\u6307\u5357\u300b\u5c31AEG\u5916\u79d1\u6cbb\u7597\u7684\u89c4\u5b9a\u5747\u6709\u4e00\u5b9a\u7a0b\u5ea6\u7684\u4fee\u6b63\u3002\u56e0\u6b64\uff0c\u6709\u5fc5\u8981\u5bf9\u300a\u98df\u7ba1\u80c3\u7ed3\u5408\u90e8\u817a\u764c\u5916\u79d1\u6cbb\u7597\u4e2d\u56fd\u4e13\u5bb6\u5171\u8bc6\uff082018\u7248\uff09\u300b\u8fdb\u884c\u66f4\u65b0\u3002<\/p>\n<p>\u300a\u98df\u7ba1\u80c3\u7ed3\u5408\u90e8\u817a\u764c\u5916\u79d1\u6cbb\u7597\u4e2d\u56fd\u4e13\u5bb6\u5171\u8bc6\uff082024\u7248\uff09\u300b\uff08\u4ee5\u4e0b\u7b80\u79f0\u300a2024\u7248\u5171\u8bc6\u300b\uff09\u5728\u4e2d\u56fd\u533b\u5e08\u534f\u4f1a\u5185\u955c\u533b\u5e08\u5206\u4f1a\u8179\u8154\u955c\u5916\u79d1\u4e13\u4e1a\u7ec4\u3001\u56fd\u9645\u98df\u7ba1\u75be\u75c5\u5b66\u4f1a\u4e2d\u56fd\u5206\u4f1a\uff08CSDE\uff09\u3001\u4e2d\u56fd\u98df\u7ba1\u80c3\u7ed3\u5408\u90e8\u817a\u764c\u7814\u7a76\u534f\u4f5c\u7ec4\u3001\u4e2d\u56fd\u6297\u764c\u534f\u4f1a\u80c3\u764c\u4e13\u59d4\u4f1a\u548c\u4e2d\u534e\u533b\u5b66\u4f1a\u80bf\u7624\u5206\u4f1a\u80c3\u80a0\u80bf\u7624\u5b66\u7ec4\u7684\u5171\u540c\u7275\u5934\u548c\u7ec4\u7ec7\u4e0b\uff0c\u753124\u540d\u80f8\u5916\u79d1\u548c25\u540d\u80c3\u80a0\u5916\u79d1\u4e13\u5bb6\u7ec4\u6210\u300a2024\u7248\u5171\u8bc6\u300b\u4e13\u5bb6\u7ec4\uff0c\u4e25\u683c\u6309\u7167\u4e2d\u56fd\u6307\u5357\u548c\u5171\u8bc6\u7684\u79d1\u5b66\u6027\uff08Scientificity\uff09\u3001\u900f\u660e\u6027\uff08Transparency\uff09\u548c\u9002\u7528\u6027\uff08Applicability\uff09\u7684\u8bc4\u7ea7\uff08Rankings\uff09\u8981\u6c42\uff08\u7f29\u5199\u4e3aSTAR\u539f\u5219\uff09\u8fdb\u884c\u7f16\u64b0<sup>[12]<\/sup>\uff1b\u5bf9\u4e8e\u5171\u8bc6\u4e2d\u6bcf\u9879\u9648\u8ff0\u548c\u63a8\u8350\u610f\u89c1\u5747\u81f3\u5c11\u67093\u4f4d\u76f8\u5173\u9886\u57df\u7684\u4e13\u5bb6\u603b\u7ed3\uff0c\u5e76\u5c06\u5176\u7ed3\u8bba\u63d0\u4f9b\u7ed9\u4e13\u5bb6\u7ec4\u3002\u7ecf\u8fc7\u53cd\u590d\u8ba8\u8bba\u5f62\u6210\u521d\u7a3f\u3002\u5e76\u4e8e2023\u5e7411\u670826\u65e5\uff0c\u9488\u5bf9\u521d\u7a3f\u4e13\u95e8\u53ec\u5f00\u7ebf\u4e0a\u300a2024\u7248\u5171\u8bc6\u300b\u4e13\u5bb6\u8ba8\u8bba\u4f1a\uff0c\u5bf9\u90e8\u5206\u5185\u5bb9\u63d0\u51fa\u4fee\u8ba2\u610f\u89c1\uff1b\u6309\u7167Delphi\u65b9\u6cd5<sup>[13]<\/sup>\u8fdb\u884c\u4e24\u8f6e\u533f\u540d\u6295\u7968\u540e\uff0c\u4ea7\u751f\u5404\u6761\u76ee\u7684\u63a8\u8350\u610f\u89c1\uff0c\u5e76\u540e\u9644\u4e13\u5bb6\u7ec4\u8d5e\u540c\u7387\u4ee5\u53ca\u76f8\u5e94\u8bc4\u8ff0\uff0c\u63d0\u4f9b\u7406\u7531\u548c\u8bc1\u636e\u6c34\u5e73\u3002\u6295\u7968\u8868\u51b3\u5206\u4e3a6\u7ea7\uff1a\u5b8c\u5168\u540c\u610f\uff08100%\uff09\u3001\u57fa\u672c\u540c\u610f\uff0880%\uff09\u3001\u90e8\u5206\u540c\u610f\uff0860%\uff09\u3001\u90e8\u5206\u53cd\u5bf9\uff0840%\uff09\u3001\u8f83\u591a\u53cd\u5bf9\uff0820%\uff09\u548c\u5b8c\u5168\u53cd\u5bf9\uff080\uff09\u3002\u5728\u7b2c\u4e00\u8f6e\u6295\u7968\u540e\u8fdb\u884c\u4e13\u5bb6\u7ec4\u5168\u4f53\u6210\u5458\u8ba8\u8bba\uff0c\u5bf9\u300a2024\u7248\u5171\u8bc6\u300b\u5185\u5bb9\u4e2d\u5b58\u5728\u5206\u6b67\u548c\u4e89\u8bae\u7684\u90e8\u5206\u63d0\u51fa\u4fee\u8ba2\uff0c\u518d\u8fdb\u884c\u7b2c2\u8f6e\u6295\u7968\uff0c\u5f97\u51fa\u6700\u7ec8\u4e13\u5bb6\u7ec4\u8d5e\u540c\u7387\u30022023\u5e7412\u67083\u65e5\uff0c\u5b8c\u6210\u4e13\u5bb6\u7ec4\u7ebf\u4e0a\u5168\u5458\u901a\u8baf\u8bc4\u5ba1\u4e4b\u540e\uff0c\u5f62\u6210\u300a2024\u7248\u5171\u8bc6\u300b\u7ec8\u7a3f\uff0c\u5e76\u5728\u5f97\u5230\u4e13\u5bb6\u7ec4\u5168\u4f53\u6210\u5458\u7684\u8ba4\u53ef\u540e\u4e88\u4ee5\u53d1\u5e03\u3002<\/p>\n<p>\u300a2024\u7248\u5171\u8bc6\u300b\u53c2\u8003\u6587\u732e\u4e2d\uff0c\u56de\u987e\u6027\u4e34\u5e8a\u7814\u7a76\u3001\u524d\u77bb\u6027\u4e34\u5e8a\u7814\u7a76\u3001Meta\u5206\u6790\u548c\u968f\u673a\u5bf9\u7167\u8bd5\u9a8c\u5747\u901a\u8fc7\u68c0\u7d22PubMed\u6570\u636e\u5e93\u83b7\u5f97\u3002\u6587\u732e\u68c0\u7d22\u65f6\u95f4\u4e3a2018\u5e747\u6708\u81f32023\u5e7411\u67081\u65e5\u3002\u53e6\u5916\uff0cUICC\/AJCC\u764c\u75c7\u5206\u671f\u7cfb\u7edf\u7b2c8\u7248<sup>[14]<\/sup>\u3001\u98df\u7ba1\u764c\u53ca\u98df\u7ba1\u80c3\u7ed3\u5408\u90e8\u764cNCCN\u6307\u5357\uff082023\u7248.V2\uff09<sup>[15]<\/sup>\u3001\u80c3\u764cNCCN\u6307\u5357\uff082022\u7248.V2\uff09<sup>[16]<\/sup>\u3001\u65e5\u672c\u80c3\u764c\u6cbb\u7597\u6307\u5357\uff08\u7b2c5\u7248\u3001\u7b2c6\u7248\uff09<sup>[17-18]<\/sup>\u3001\u98df\u7ba1\u764c\u89c4\u8303\u5316\u8bca\u7597\u6307\u5357<sup>[19]<\/sup>\u3001\u4e2d\u56fd\u8179\u8154\u955c\u80c3\u764c\u6839\u6cbb\u624b\u672f\u8d28\u91cf\u63a7\u5236\u4e13\u5bb6\u5171\u8bc6\uff082022\u7248\uff09<sup>[20]<\/sup>\u548cSiewert\u2161\u578b\u98df\u7ba1\u80c3\u7ed3\u5408\u90e8\u817a\u764c\u8154\u955c\u624b\u672f\u6cbb\u7597\u4e2d\u56fd\u4e13\u5bb6\u5171\u8bc6\uff082023\u7248\uff09<sup>[21]<\/sup>\u4ea6\u7eb3\u5165\u4f5c\u4e3a\u5171\u8bc6\u53c2\u8003\u4f9d\u636e\u3002\u8bc1\u636e\u7ea7\u522b\u548c\u63a8\u8350\u5f3a\u5ea6\u5206\u7ea7\u91c7\u7528GRADE\uff08grading of recommendations assessment\uff0cdevelopment and evaluation\uff09\u7cfb\u7edf<sup>[22-23]<\/sup>\u3002\u89c1\u88681\u3002\u9700\u7279\u522b\u8bf4\u660e\u7684\u662f\uff0c\u5176\u4e2d\u5df2\u6709\u76f8\u5173\u6307\u5357\u63a8\u8350\u7684\u9648\u8ff0\u3001\u4f46\u5c1a\u65e0\u76f8\u5173\u9ad8\u8d28\u91cf\u4e34\u5e8a\u7814\u7a76\u652f\u6491\u7684\uff0c\u672c\u5171\u8bc6\u4e2d\u5219\u4ea6\u4f5c\u4e3a\u9ad8\u8d28\u91cf\u8bc1\u636e\u63a8\u8350\u3002NCCN\u7684\u98df\u7ba1\u764c\u548c\u98df\u7ba1\u80c3\u7ed3\u5408\u90e8\u764c\u4e34\u5e8a\u6307\u5357\u4e2d\u63a8\u8350AEG\u5b9c\u4ee5\u591a\u5b66\u79d1\u534f\u4f5c\u8bca\u7597\u6a21\u5f0f\u4e3a\u57fa\u7840\u8fdb\u884c\u7efc\u5408\u6cbb\u7597<sup>[15]<\/sup>\u3002\u300a2024\u7248\u5171\u8bc6\u300b\u4e5f\u5c06\u8fdb\u4e00\u6b65\u589e\u5f3a\u80f8\u5916\u79d1\u548c\u80c3\u80a0\u5916\u79d1\u533b\u751f\u5bf9AEG\u8fd9\u4e00\u7c7b\u578b\u80bf\u7624\u8ba4\u8bc6\u548c\u8bca\u7597\u7684\u540c\u8d28\u6027\uff0c\u7279\u522b\u662fAEG\u624b\u672f\u8d28\u91cf\u63a7\u5236\uff0c\u4f7f\u6211\u56fdAEG\u5916\u79d1\u6cbb\u7597\u66f4\u52a0\u89c4\u8303\u5316\u548c\u540c\u8d28\u5316\uff0c\u4e0d\u65ad\u63d0\u5347\u6cbb\u7597\u6548\u679c\uff0c\u5207\u5b9e\u6539\u5584\u60a3\u8005\u9884\u540e\u3002<\/p>\n<\/p>\n<p>\u4e00\u98df\u7ba1\u80c3\u7ed3\u5408\u90e8\u817a\u764c\u7684\u5b9a\u4e49\u3001\u5206\u671f\u4e0e\u5206\u578b<\/p>\n<p>\u63a8\u8350\u610f\u89c11.\u98df\u7ba1\u80c3\u7ed3\u5408\u90e8\u817a\u764c\uff08AEG\uff09\u5b9a\u4e49\uff1a\u4e0d\u8bba\u80bf\u7624\u4e2d\u5fc3\uff08\u6216\u4e3b\u4f53\uff09\u5904\u4e8e\u4f55\u79cd\u89e3\u5256\u4f4d\u7f6e\uff0c\u98df\u7ba1\u2043\u80c3\u89e3\u5256\u4ea4\u754c\u4e0a\u4e0b\u54045 cm\u533a\u95f4\u4ee5\u5185\u7684\u817a\u764c\uff0c\u5e76\u8de8\u8d8a\u98df\u7ba1\u80c3\u7ed3\u5408\u90e8\uff08esophagogastric junction\uff0cEGJ\uff09\uff0c\u5373\u4e3aAEG\uff08\u8bc1\u636e\u7ea7\u522b\uff1a\u9ad8\uff0c\u63a8\u8350\u5f3a\u5ea6\uff1a\u5f3a\u63a8\u8350\uff0c\u4e13\u5bb6\u7ec4\u8d5e\u540c\u7387\uff1a100%\uff09\u3002<\/p>\n<p>\u63a8\u8350\u610f\u89c12.AEG\u5206\u671f\uff1a\u5efa\u8baeSiewert\u2160\u578bAEG\uff0c\u6309\u98df\u7ba1\u764c\u8fdb\u884c\u5206\u671f\uff1bSiewert\u2161\u578b\u548c\u2162\u578bAEG\uff0c\u53c2\u7167\u80c3\u764c\u8fdb\u884c\u5206\u671f\uff08\u8bc1\u636e\u7ea7\u522b\uff1a\u9ad8\uff0c\u63a8\u8350\u5f3a\u5ea6\uff1a\u5f31\u63a8\u8350\uff0c\u4e13\u5bb6\u7ec4\u8d5e\u540c\u7387\uff1a97.87%\uff09\u3002<\/p>\n<p>\u63a8\u8350\u610f\u89c13.AEG\u5206\u578b\uff1aSiewert\u5206\u578b\u4ecd\u662f\u76ee\u524d\u8f83\u4e3a\u666e\u904d\u5b9e\u7528\u7684\u5206\u578b\u65b9\u5f0f\uff0c\u5bf9\u624b\u672f\u5f84\u8def\u7684\u8bbe\u8ba1\u6709\u8f83\u597d\u7684\u6307\u5bfc\u4ef7\u503c\uff08\u8bc1\u636e\u7ea7\u522b\uff1a\u9ad8\uff0c\u63a8\u8350\u5f3a\u5ea6\uff1a\u5f3a\u63a8\u8350\uff0c\u4e13\u5bb6\u7ec4\u8d5e\u540c\u7387\uff1a100%\uff09\u3002<\/p>\n<p>\u5faa\u8bc1\u533b\u5b66\u8bc1\u636e\uff1aEGJ\u662f\u6307\u7ba1\u72b6\u98df\u7ba1\u4e0e\u56ca\u72b6\u80c3\u4e4b\u95f4\u7ed3\u5408\u7684\u865a\u62df\u89e3\u5256\u4ea4\u754c\u7ebf\uff0c\u5176\u5b9a\u4e49\u6db5\u76d6\u5185\u955c\u3001\u4e0a\u6d88\u5316\u9053\u9020\u5f71\u548c\u75c5\u7406\u5b66\u4e09\u65b9\u9762\u30022022\u5e74\uff0c\u98df\u7ba1\u80c3\u7ed3\u5408\u90e8\u89e3\u5256\u3001\u75c5\u7406\u751f\u7406\u53ca\u4e34\u5e8a\u610f\u4e49\u4eac\u90fd\u56fd\u9645\u5171\u8bc6<sup>[24]<\/sup>\u8ba4\u4e3a\uff0cEGJ\u5185\u955c\u4e0b\u8868\u73b0\u4e3a\u98df\u7ba1\u4e0b\u7aef\u7eb5\u884c\u6805\u680f\u72b6\u8840\u7ba1\u672b\u68a2\u6216\u80c3\u9ecf\u819c\u76b1\u895e\u7684\u8fd1\u4fa7\u7f18\uff1b\u4e0a\u6d88\u5316\u9053\u94a1\u9910\u9020\u5f71\u4e2dEGJ\u5b9a\u4e49\u4e3a\u98df\u7ba1\u4e0b\u6bb5\u6700\u4e3a\u72ed\u7a84\uff08\u8fc7His\u89d2\u9876\u70b9\uff0c\u4e14\u5782\u76f4\u4e8e\u8179\u6bb5\u98df\u7ba1\u7eb5\u5411\u5207\u7ebf\uff09\u7684\u533a\u57df\uff1b\u7ec4\u7ec7\u5b66\u4e0a\u7684\u9cde\u67f1\u72b6\u4e0a\u76ae\u4ea4\u754c\u5904\uff08squamocolumnar junction\uff0cSCJ\uff09\u4e0eEGJ\u53ef\u4ee5\u4e0d\u76f8\u91cd\u5408<sup>[25\u204326]<\/sup>\u3002\u300a2024\u7248\u5171\u8bc6\u300b\u8ba4\u4e3a\uff0c\u4e34\u5e8a\u5b9e\u8df5\u4e2d\u53c2\u8003\u98df\u7ba1\u2043\u80c3\u89e3\u5256\u4ea4\u754c\u7ebf\u66f4\u4e3a\u5408\u7406\u3002\u56e0\u6b64\uff0c\u540e\u6587\u4e2d\u6240\u63d0EGJ\u5747\u6307\u89e3\u5256\u4ea4\u754c\u7ebf\u3002\u53c2\u8003WHO\u5173\u4e8e\u6d88\u5316\u7cfb\u7edf\u80bf\u7624\u5206\u7c7b\u5b9a\u4e49\uff0c\u4e0d\u8bba\u80bf\u7624\u4e2d\u5fc3\uff08\u6216\u4e3b\u4f53\uff09\u5904\u4e8e\u4f55\u79cd\u89e3\u5256\u4f4d\u7f6e\uff0c\u4f4d\u4e8eEGJ\u4e0a\u4e0b\u54045 cm\u8303\u56f4\u4ee5\u5185\u7684\u817a\u764c\uff0c\u5e76\u8de8\u8d8aEGJ\uff0c\u5373\u5b9a\u4e49\u4e3aAEG<sup>[27]<\/sup>\u3002\u6709\u5173AEG\u7684\u4e2d\u6587\u672f\u8bed\uff0c\u300a2024\u7248\u5171\u8bc6\u300b\u7ee7\u7eed\u4f7f\u7528\u201c\u98df\u7ba1\u201d\u800c\u975e\u201c\u98df\u9053\u201d<sup>[19]<\/sup>\uff1b\u201c\u7ed3\u5408\u90e8\u201d\u800c\u975e\u201c\u4ea4\u754c\u90e8\u201d\u3001\u201c\u63a5\u5408\u5904\u201d\u6216\u201c\u8fde\u63a5\u5904\u201d\u7b49\u3002Siewert\u5206\u578b\uff1a\u2160\u578b\uff0cEGJ\u4ee5\u4e0a1~5 cm\uff1b\u2161\u578b\uff0c\u98df\u7ba1\u2043\u80c3\u89e3\u5256\u4ea4\u754c\u4ee5\u4e0a1 cm\u81f3\u98df\u7ba1\u2043\u80c3\u89e3\u5256\u4ea4\u754c\u4ee5\u4e0b2 cm\uff1b\u2162\u578b\uff0c\u98df\u7ba1\u2043\u80c3\u89e3\u5256\u4ea4\u754c\u4ee5\u4e0b2~5 cm<sup>[28\u204329]<\/sup>\u3002<\/p>\n<p>AEG\u6cbb\u7597\u51b3\u7b56\u5df2\u5f62\u6210\u57fa\u4e8e\u7cbe\u51c6\u4e34\u5e8a\u5206\u671f\u7684\u4e2a\u4f53\u5316\u8bca\u65ad\u2043\u6cbb\u7597\u6a21\u5f0f<sup>[30\u204334]<\/sup>\u3002AJCC\/UICC\u7b2c8\u7248\u5206\u671f\u7cfb\u7edf\u5bf9AEG\u7684\u5206\u671f\u7cfb\u7edf\u8fdb\u884c\u4e86\u8f83\u5927\u7684\u4fee\u8ba2\uff0c\u89c4\u5b9aSiewert\u2160\u578b\u5e94\u6309\u7167\u98df\u7ba1\u764c\u5206\u671f\u7cfb\u7edf\u8fdb\u884c\uff0cSiewert\u2162\u578bAEG\u5e94\u6309\u7167\u80c3\u764c\u5206\u671f\u7cfb\u7edf\u8fdb\u884c<sup>[35\u204336]<\/sup>\u3002Siewert\u2161\u578bAEG\u7684\u5206\u671f\u5c1a\u5b58\u4e89\u8bae\uff0c\u6211\u56fd\u4e00\u9879\u591a\u4e2d\u5fc3\u56de\u987e\u6027\u4e34\u5e8a\u7814\u7a76\u7eb3\u51651 410\u4f8b\u75c5\u4f8b\u7684\u7814\u7a76\u7ed3\u679c\u663e\u793a\uff0cAJCC\/UICC\u7b2c8\u7248\u80c3\u764c\u5206\u671f\u7cfb\u7edf\u76f8\u8f83\u4e8e\u98df\u7ba1\u764c\u5206\u671f\u7cfb\u7edf\uff0c\u80fd\u66f4\u52a0\u51c6\u786e\u5730\u63cf\u8ff0Siewert\u2161\u3001\u2162\u578bAEG\u7684\u9884\u540e\uff0c\u80c3\u764c\u5206\u671f\u7cfb\u7edf\u6a21\u578b\u7684C\u2043index\u8f83\u98df\u7ba1\u764c\u5206\u671f\u7cfb\u7edf\u8f83\u9ad8\uff080.724\u6bd40.694\uff0cP=0.005\uff09<sup>[37]<\/sup>\u30022022\u5e74\uff0c\u65e5\u672c\u98df\u7ba1\u5b66\u4f1a\u53d1\u5e03\u7684\u7b2c12\u7248\u65e5\u672c\u300a\u98df\u7ba1\u764c\u5904\u7406\u89c4\u7ea6\u300b\u6307\u51fa\uff0c\u98df\u7ba1\u80c3\u7ed3\u5408\u90e8\u764c\u7684\u5206\u671f\u5e94\u6839\u636e\u80bf\u7624\u7ec4\u7ec7\u7c7b\u578b\u9009\u62e9\uff0c\u817a\u764c\u53c2\u8003\u80c3\u764c\u5206\u671f\u7cfb\u7edf\uff0c\u800c\u9cde\u764c\u53c2\u8003\u98df\u7ba1\u764c\u5206\u671f\u7cfb\u7edf<sup>[38]<\/sup>\u3002\u6211\u56fd\u300aSiewert\u2161\u578b\u98df\u7ba1\u80c3\u7ed3\u5408\u90e8\u817a\u764c\u8154\u955c\u624b\u672f\u6cbb\u7597\u4e2d\u56fd\u4e13\u5bb6\u5171\u8bc6\uff082023\u7248\uff09\u300b<sup>[21]<\/sup>\u4ea6\u63a8\u8350\uff0cSiewert\u2161\u578bAEG\u6309\u7167\u7b2c8\u7248\u80c3\u764c\u5206\u671f\u7cfb\u7edf\u8fdb\u884c\u5206\u671f\u3002\u4e3a\u4e86\u4fbf\u4e8e\u4e0d\u540c\u5355\u4f4d\u3001\u4e0d\u540c\u4e13\u4e1a\uff08\u80f8\u5916\u79d1\u3001\u666e\u901a\u79d1\u548c\u80bf\u7624\u79d1\uff09\u95f4\u76f8\u4e92\u4ea4\u6d41\uff0c\u672c\u5171\u8bc6\u5efa\u8bae\uff1aAEG\u7684\u5206\u671f\u6807\u51c6\u7edf\u4e00\u6309\u7167Siewert\u5206\u578b\u8fdb\u884c\u9009\u62e9\uff0cSiewert\u2160\u578b\u6309\u7167\u98df\u7ba1\u764c\u8fdb\u884c\u5206\u671f\uff1bSiewert\u2161\u578b\u548c\u2162\u578b\u5219\u53c2\u7167\u80c3\u764c\u5206\u671f\u7cfb\u7edf\u3002\u89c1\u56fe1\u3002<\/p>\n<\/p>\n<p>\u4e8cAEG\u7684\u624b\u672f\u8def\u5f84<\/p>\n<p>AEG\u7684\u89e3\u5256\u4f4d\u7f6e\u7279\u6b8a\uff0c\u624b\u672f\u6d89\u53ca\u80f8\u8154\u548c\u8179\u8154\u4e24\u4e2a\u533a\u57df\uff0c\u5408\u7406\u7684\u624b\u672f\u8def\u5f84\u5e94\u517c\u987e\u80bf\u7624\u5207\u9664\u3001\u6dcb\u5df4\u7ed3\u6e05\u626b\u3001\u624b\u672f\u5207\u7f18\u53ca\u5b89\u5168\u6027\u3002\u5e38\u89c1AEG\u7684\u624b\u672f\u8def\u5f84\u5305\u62ec\uff1a\uff081\uff09\u7ecf\u5de6\u80f8\u8179\u8054\u5408\u5207\u53e3\uff08left thoracoabdominal\uff0c&nbsp;LTA\uff09\uff1b\uff082\uff09\u4e0a\u8179\u53f3\u80f8\u4e24\u5207\u53e3\uff08Ivor\u2043Lewis\uff09\uff1b\uff083\uff09\u4e0a\u8179\u3001\u5de6\u80f8\u4e24\u5207\u53e3\uff1b\uff084\uff09\u9888\u3001\u53f3\u80f8\u3001\u4e0a\u8179\u4e09\u5207\u53e3\uff08McKeown\uff09\uff1b\uff085\uff09\u5de6\u80f8\u8179\u8054\u5408\u5207\u53e3\uff1b\uff086\uff09\u7ecf\u8179\u8188\u808c\u98df\u7ba1\u88c2\u5b54\uff08transhiatal approach\uff0cTH\uff09\u5f84\u8def\u3002<\/p>\n<p>\u63a8\u8350\u610f\u89c14.\u672f\u524d\u51c6\u786eSiewert\u5206\u578b\u548c\u98df\u7ba1\u53d7\u7d2f\u957f\u5ea6\u5bf9AEG\u624b\u5165\u8def\u6709\u91cd\u8981\u5f71\u54cd\u3002\u5efa\u8bae\u5e38\u89c4\u884c\u4e0a\u6d88\u5316\u9053\u9020\u5f71\u68c0\u67e5\uff0c\u5e76\u7ed3\u5408\u80c3\u955c\uff0c\u7efc\u5408\u8bc4\u4f30AEG\u7684\u5206\u578b\u548c\u98df\u7ba1\u53d7\u7d2f\u957f\u5ea6\uff08\u8bc1\u636e\u7ea7\u522b\uff1a\u4e2d\uff0c\u63a8\u8350\u5f3a\u5ea6\uff1a\u5f3a\u63a8\u8350\uff0c\u4e13\u5bb6\u7ec4\u8d5e\u540c\u7387\uff1a95.74%\uff09<\/p>\n<p>\u5faa\u8bc1\u533b\u5b66\u8bc1\u636e\uff1aNCCN\u6307\u5357\u5236\u5b9a\u7684\u4e34\u5e8a\u8bca\u7597\u6d41\u7a0b\u4e2d\uff0c\u8981\u6c42\u5e38\u89c4\u8fdb\u884c\u672f\u524dSiewert\u5206\u578b<sup>[15\u204316]<\/sup>\u3002\u8fd9\u5bf9\u624b\u672f\u65b9\u5f0f\u7684\u9009\u62e9\u6709\u660e\u663e\u5f71\u54cd\u3002\u5728\u897f\u65b9\u548c\u65e5\u672c\uff0c\u65e0\u8bba\u7efc\u5408\u6cbb\u7597\u548c\u5916\u79d1\u6cbb\u7597\uff0c\u5176\u65b9\u6848\u7684\u8bbe\u8ba1\u5747\u4e3b\u8981\u57fa\u4e8eAEG\u7684Siewert\u5206\u578b<sup>[31,39]<\/sup>\u3002\u4e0a\u6d88\u5316\u9053\u9020\u5f71\u53ef\u4ee5\u6d4b\u91cf\u98df\u7ba1\u53d7\u7d2f\u957f\u5ea6\uff0c\u5e76\u8bc4\u4f30\u80bf\u7624\u7684\u4e2d\u5fc3\u4f4d\u7f6e\u3002\u56e0\u6b64\uff0c\u4e34\u5e8a\u4e0a\u5efa\u8bae\u7ed3\u5408\u4e0a\u6d88\u5316\u9053\u9020\u5f71\u68c0\u67e5\uff0c\u5728\u5236\u5b9a\u6cbb\u7597\u65b9\u6848\u524d\u4f5c\u51faSiewert\u5206\u578b\u548c\u98df\u7ba1\u53d7\u7d2f\u5927\u81f4\u9ad8\u5ea6\u7684\u5224\u65ad\u3002\u53e6\u5916\uff0c\u5e38\u89c4\u68c0\u67e5\u5e94\u5305\u62ec\u4e0a\u6d88\u5316\u9053\u5185\u955c\u4ee5\u53ca\u5168\u8179\u90e8\u589e\u5f3aCT\u6216MRI<sup>[11, 16\u204318]<\/sup>\u3002<\/p>\n<p>\u63a8\u8350\u610f\u89c15. \u7ecf\u80f8\u5f84\u8def\u9002\u7528\u4e8eSiewert\u2160\u578bAEG\uff08\u8bc1\u636e\u7ea7\u522b\uff1a\u9ad8\uff0c\u63a8\u8350\u5f3a\u5ea6\uff1a\u5f3a\u63a8\u8350\uff0c\u4e13\u5bb6\u7ec4\u8d5e\u540c\u7387\uff1a100%\uff09\u3002<\/p>\n<p>\u63a8\u8350\u610f\u89c16. \u7ecf\u8179\u6216\u7ecf\u8179\u98df\u7ba1\u8188\u808c\u88c2\u5b54\u5f84\u8def\u9002\u7528\u4e8eSiewert\u2162\u578bAEG\uff08\u8bc1\u636e\u7ea7\u522b\uff1a\u9ad8\uff0c\u63a8\u8350\u5f3a\u5ea6\uff1a\u5f3a\u63a8\u8350\uff0c\u4e13\u5bb6\u7ec4\u8d5e\u540c\u7387\uff1a100%\uff09\u3002<\/p>\n<p>\u63a8\u8350\u610f\u89c17. Siewert\u2161\u578bAEG\u7684\u624b\u672f\u5f84\u8def\u76ee\u524d\u5c1a\u6709\u4e89\u8bae\uff0c\u5efa\u8bae\u98df\u7ba1\u53d7\u7d2f\u8ddd\u79bb\u22642 cm\u8005\u8003\u8651\u7ecf\u8179\u98df\u7ba1\u8188\u808c\u88c2\u5b54\u5f84\u8def\uff1b&gt;2 cm\u8005\u53ef\u8003\u8651\u7ecf\u80f8\u5f84\u8def\uff08\u8bc1\u636e\u7ea7\u522b\uff1a\u4e2d\uff0c\u63a8\u8350\u7ea7\u522b\uff1a\u5f31\u63a8\u8350\uff0c\u4e13\u5bb6\u7ec4\u8d5e\u540c\u7387\uff1a93.62%\uff09\u3002<\/p>\n<p>\u5faa\u8bc1\u533b\u5b66\u8bc1\u636e\uff1a\u968f\u7740\u8179\u8154\u955c\u5fae\u521b\u6280\u672f\u7684\u5feb\u901f\u53d1\u5c55\u548c\u5e94\u7528\u666e\u53ca\uff0c\u7ecf\u8179\u5165\u8def\u5bf9AEG\u7684\u6839\u6cbb\u6027\u5207\u9664\u5728\u6280\u672f\u5c42\u9762\u53d6\u5f97\u4e86\u663e\u8457\u8fdb\u6b65\uff0c\u7279\u522b\u662f\u5728\u672f\u540e\u5e76\u53d1\u75c7\u63a7\u5236\u548c\u6574\u4f53\u751f\u6d3b\u8d28\u91cf\u63d0\u5347\u65b9\u9762\uff0c\u5747\u4f18\u4e8e\u7ecf\u80f8\u6216\u80f8\u8179\u8054\u5408\u5165\u8def<sup>[39\u204340]<\/sup>\u3002\u7136\u800c\uff0c\u5bf9\u4e8e\u7eb5\u9694\u6dcb\u5df4\u7ed3\u9ad8\u8f6c\u79fb\u98ce\u9669\u7684\u60a3\u8005\uff0c\u7ecf\u8179\u5165\u8def\u65b9\u6cd5\u5bf9\u7eb5\u9694\u6dcb\u5df4\u7ed3\u5207\u9664\u7684\u53ef\u53ca\u6027\u4ecd\u6709\u4e0d\u8db3\uff0c\u5bfc\u81f4\u5176\u6839\u6cbb\u6027\u6548\u679c\u4e0d\u4f73\u3002\u5f53\u524d\u7814\u7a76\u663e\u793a\uff0c\u5728Siewert\u5206\u7c7b\u2160\u3001\u2161\u3001\u2162\u578bAEG\u4e2d\uff0c\u7eb5\u9694\u6dcb\u5df4\u7ed3\u8f6c\u79fb\u7387\u5206\u522b\u53ef\u9ad8\u8fbe65%\u300129.5%\u548c9.3%<sup>[41\u204342]<\/sup>\u3002\u8377\u5170\u4e00\u9879\u968f\u673a\u5bf9\u7167\u7814\u7a76\u4e2d\u7eb3\u5165220\u4f8bSiewert\u2160\u3001\u2161\u578bAEG\u60a3\u8005\uff0c\u5206\u4e3a\u975e\u7ecf\u80f8\u4e0e\u7ecf\u80f8\u5165\u8def\u624b\u672f\u7ec4\u3002\u7ed3\u679c\u663e\u793a\uff0c\u4e24\u7ec4\u60a3\u80055\u5e74\u603b\u4f53\u751f\u5b58\u7387\uff08overall survival\uff0cOS\uff09\u5dee\u5f02\u65e0\u7edf\u8ba1\u5b66\u610f\u4e49\uff0834%\u6bd436%\uff0cP=0.71\uff09\u3002\u7136\u800c\uff0c\u5728pN+\u671f\u60a3\u8005\u4e2d\uff0c\u7ecf\u80f8\u5165\u8def\u7ec4\u76845\u5e74\u65e0\u75c5\u751f\u5b58\u7387\uff08disease\u2043free survival\uff0cDFS\uff09\u663e\u8457\u9ad8\u4e8e\u975e\u7ecf\u80f8\u7ec4\uff0864%\u6bd423%\uff0cP=0.02\uff09\uff0c\u51f8\u663e\u7ecf\u80f8\u5f84\u8def\u5728\u6dcb\u5df4\u7ed3\u6e05\u626b\u4e2d\u7684\u6f5c\u5728\u4f18\u52bf<sup>[43]<\/sup>\u3002\u5728\u7eb5\u9694\u6dcb\u5df4\u7ed3\u6e05\u626b\u7684\u624b\u672f\u8def\u5f84\u9009\u62e9\u4e0a\uff0c\u65e2\u53ef\u4ee5\u901a\u8fc7\u5de6\u80f8\u5165\u8def\uff0c\u4e5f\u53ef\u4ee5\u9009\u62e9\u53f3\u80f8\u5165\u8def\u3002\u76f8\u8f83\u4e4b\u4e0b\uff0c\u53f3\u80f8\u5165\u8def\u7531\u4e8e\u65e0\u4e3b\u52a8\u8109\u5f13\u906e\u6321\uff0c\u80fd\u591f\u5b9e\u73b0\u66f4\u4e3a\u5f7b\u5e95\u7684\u7eb5\u9694\u6dcb\u5df4\u7ed3\u6e05\u626b\u3002\u8fd1\u671f\u4e00\u9879\u591a\u4e2d\u5fc3\u3001\u524d\u77bb\u6027\u3001\u968f\u673a\u5bf9\u7167\u7814\u7a76\uff08NST1501\uff09\u53d1\u73b0\uff0c\u7ecf\u53f3\u80f8\u5165\u8def\u76f8\u8f83\u4e8e\u7ecf\u5de6\u80f8\u5165\u8def\u624b\u672f\u53ef\u6e05\u626b\u66f4\u591a\u7684\u6dcb\u5df4\u7ed3\uff0823.61\u6bd421.92\u679a\uff0cP=0.015\uff09\uff0c\u5e76\u663e\u8457\u63d0\u9ad8\u98df\u7ba1\u764c\u60a3\u8005\u672f\u540eOS\uff0867.8%\u6bd451.8%\uff0cP=0.022\uff09<sup>[44]<\/sup>\u3002\u56e0\u6b64\uff0c\u5f53\u524d\u7684\u98df\u7ba1\u764c\u6307\u5357\u5bf9\u80f8\u6bb5\u98df\u7ba1\u764c\u624b\u672f\uff0c\u63a8\u8350\u7ecf\u53f3\u80f8\u5165\u8def<sup>[45]<\/sup>\u3002\u5bf9\u4e8eSiewert\u2160\u578bAEG\u60a3\u8005\uff0c\u63a8\u8350\u53f3\u80f8\u5f84\u8def\uff0c\u5305\u62ec\u4e0a\u8179\u53f3\u80f8\u4e24\u5207\u53e3\uff08Ivor\u2043leiws\uff09\u6216\u9888\u3001\u53f3\u80f8\u3001\u4e0a\u8179\u4e09\u5207\u53e3\uff08McKeown\uff09\u672f\u5f0f\u3002<\/p>\n<p>\u4e00\u9879\u7eb3\u516512\u9879\u7814\u7a76\u5171\u8ba11 105\u4f8b\u60a3\u8005\u7684Meta\u5206\u6790\u53d1\u73b0\uff0cAEG\u7ecf\u80f8\u5207\u9664\u7ec4\u4e0e\u7ecf\u8179\u5207\u9664\u7ec4\u5728\u672f\u540e\u751f\u5b58\u7387\u3001\u672f\u540e\u53d1\u75c5\u7387\u53ca\u75c5\u6b7b\u7387\u65b9\u9762\u5dee\u5f02\u65e0\u7edf\u8ba1\u5b66\u610f\u4e49\uff0c\u4e24\u79cd\u624b\u672f\u65b9\u5f0f\u90fd\u53ef\u63a5\u53d7\uff1b\u4f46\u7eb3\u5165\u7814\u7a76\u7684\u8d28\u91cf\u4e0d\u4f73\uff0c\u56e0\u6b64\u5bf9\u7ed3\u679c\u7684\u89e3\u91ca\u5e94\u8c28\u614e<sup>[46]<\/sup>\u3002\u6b64\u5916\uff0c\u8fd8\u6709\u4e00\u9879\u7eb3\u51658\u9879\u7814\u7a76\u5171\u8ba11 155\u4f8bAEG\u60a3\u8005\u7684Meta\u5206\u6790\u5efa\u8bae\uff0c\u5bf9Siewert\u2162\u578bAEG\u5b9c\u884c\u7ecf\u8188\u808c\u98df\u7ba1\u88c2\u5b54\u5f84\u8def\u5207\u9664\uff0c\u4f46\u957f\u671f\u7597\u6548\u5c1a\u9700\u8fdb\u4e00\u6b65\u8bc4\u4f30<sup>[47]<\/sup>\u3002\u7ecf\u80f8\u8179\u8054\u5408\u8def\u5f84\u4e3a\u6269\u5927\u624b\u672f\uff0c\u5e94\u5728\u9884\u671f\u53ef\u6839\u6cbb\u6027\u5207\u9664\u7684AEG\u75c5\u4f8b\u4e2d\u5ba1\u614e\u5730\u9009\u62e9\u6027\u5b9e\u65bd\u3002JCOG\u20439502\u968f\u673a\u5bf9\u7167\u8bd5\u9a8c\u768410\u5e74\u968f\u8bbf\u7ed3\u679c\u53d1\u73b0\uff0c\u98df\u7ba1\u53d7\u7d2f\u957f\u5ea6\u22643 cm\u7684Siewert\u2161\u3001\u2162\u578bAEG\u75c5\u4f8b\uff0c\u7ecf\u5de6\u80f8\u8179\u8054\u5408\u5207\u53e3\u5f84\u8def\u884c\u5168\u80c3D<sub>2<\/sub>\u5207\u9664\u8054\u5408\u813e\u5207\u9664\u4e0e\u7ecf\u8179\u8188\u808c\u98df\u7ba1\u88c2\u5b54\u5f84\u8def\u76f8\u540c\u672f\u5f0f\u6bd4\u8f83\uff0c\u6309Siewert\u5206\u578b\u5206\u5c42\u5206\u6790\u7ed3\u679c\u663e\u793a\uff0c\u957f\u671f\u751f\u5b58\u7ed3\u5c40\u5dee\u5f02\u5e76\u65e0\u7edf\u8ba1\u5b66\u610f\u4e49\uff0c\u4f46\u672f\u540e\u5e76\u53d1\u75c7\u98ce\u9669\u524d\u8005\u8f83\u7ecf\u8179\u8188\u808c\u88c2\u5b54\u5f84\u8def\u589e\u9ad8\uff1b\u6545\u63a8\u8350\uff0c\u98df\u7ba1\u53d7\u7d2f&lt;3 cm\u7684Siewert\u2161\u3001\u2162\u578bAEG\u75c5\u4f8b\u5e94\u9009\u62e9\u7ecf\u8179\u98df\u7ba1\u8188\u808c\u88c2\u5b54\u5f84\u8def<sup>[48\u204349]<\/sup>\u3002<\/p>\n<p>\u53e6\u6709\u4e24\u9879\u56de\u987e\u6027\u7814\u7a76\u53d1\u73b0\uff0c\u4e0a\u8179\u53f3\u80f8\u5f84\u8def\u624b\u672f\u60a3\u8005\u7684\u8fdc\u671f\u751f\u5b58\u4e0d\u52a3\u4e8e\u7ecf\u8179\u88c2\u5b54\u5f84\u8def\uff0c\u800c\u4e14\u672f\u540e\u5e76\u53d1\u75c7\u7684\u53d1\u751f\u7387\u5dee\u5f02\u65e0\u7edf\u8ba1\u5b66\u610f\u4e49\uff1b\u4f46\u5728\u4e0a\u7eb5\u9694\u6dcb\u5df4\u7ed3\u6e05\u626b\u53ca\u98df\u7ba1\u5207\u7f18\u65b9\u9762\uff0c\u4e0a\u8179\u53f3\u80f8\u5f84\u8def\u4e5f\u6bd4\u7ecf\u98df\u7ba1\u8188\u808c\u88c2\u5b54\u5f84\u8def\u5177\u6709\u4f18\u52bf<sup>[50\u204351]<\/sup>\u3002\u8d8a\u6765\u8d8a\u591a\u7684\u7814\u7a76\u8ba4\u4e3a\uff0c\u7ecf\u80f8\u6216\u7ecf\u8179\u5f84\u8def\u624b\u672f\u5747\u53ef\u5728Siewert\u2161\u578bAEG\u75c5\u4f8b\u5e94\u7528\uff0c\u800c\u4e14\u6280\u672f\u4e0a\uff0c\u7ecf\u8188\u808c\u88c2\u5b54\u5f84\u8def\u53ef\u8fbe\u5230Siewert\u2161\u578b\u5145\u5206\u7684\u98df\u7ba1\u5207\u9664\u8ddd\u79bb<sup>[52]<\/sup>\u3002\u4f46\u6709\u4e00\u9879\u5bf9\u7167\u7814\u7a76\u5374\u62a5\u9053\uff0c\u7ecf\u8188\u808c\u98df\u7ba1\u88c2\u5b54\u624b\u672f\u5f84\u8def\u5728\u60a3\u8005\u672f\u540e\u8fdc\u671f\u751f\u5b58\u3001R<sub>0<\/sub>\u5207\u9664\u7387\u3001\u6dcb\u5df4\u7ed3\u6e05\u626b\u4e2a\u6570\u548c\u672f\u540e\u5e76\u53d1\u75c7\u65b9\u9762\u8f83\u4e0a\u8179\u53f3\u80f8\u5f84\u8def\u5747\u6709\u660e\u663e\u4f18\u52bf<sup>[53]<\/sup>\u3002\u4e00\u9879\u7eb3\u51652 331\u75c5\u4f8b\u7684Meta\u5206\u6790\u7ed3\u679c\u63d0\u793a\uff0c\u7ecf\u8188\u808c\u98df\u7ba1\u88c2\u5b54\u8def\u5f84\u624b\u672f\u60a3\u8005\u5728\u672f\u540e3\u5e74\u548c5\u5e74OS\u3001\u964d\u4f4e\u672f\u540e\u80ba\u90e8\u5e76\u53d1\u75c7\u53d1\u751f\u7387\u548c\u51cf\u5c11\u672f\u4e2d\u51fa\u8840\u91cf\u7b49\u65b9\u9762\u5747\u5177\u663e\u8457\u4f18\u52bf<sup>[54]<\/sup>\u3002<\/p>\n<p>Siewert\u2161\u7684\u624b\u672f\u5f84\u8def\u5e94\u7efc\u5408\u8003\u8651\u60a3\u8005\u7684\u5168\u8eab\u4e00\u822c\u72b6\u51b5\u3001\u539f\u53d1\u80bf\u7624\u76f4\u5f84\u3001\u98df\u7ba1\u53d7\u7d2f\u957f\u5ea6\u3001\u624b\u672f\u5207\u7f18\u5b89\u5168\u8ddd\u79bb\u53ca\u5408\u7406\u7684\u6dcb\u5df4\u7ed3\u6e05\u626b\u8303\u56f4\u7b49\u56e0\u7d20\u8fdb\u884c\u4e2a\u4f53\u5316\u9009\u62e9\u3002\u5f53\u524d\u6700\u4f73\u4e34\u5e8a\u7814\u7a76\u8bc1\u636eJCOG\u20439502\u8bd5\u9a8c\u7684\u4e9a\u7ec4\u5206\u6790\u7ed3\u679c\uff0c\u652f\u6301Siewert\u2161\u578b\u3001\u98df\u7ba1\u53d7\u7d2f&lt;3 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355\u4f8b\u60a3\u8005\u7684\u835f\u8403\u5206\u6790\u663e\u793a\uff0c\u8be5\u624b\u672f\u65b9\u5f0f\u5728\u672f\u4e2d\u5931\u8840\u91cf\u3001\u672f\u540e\u80ba\u90e8\u5e76\u53d1\u75c7\u53ca\u603b\u4f53\u5e76\u53d1\u75c7\u65b9\u9762\u5747\u663e\u8457\u4f18\u4e8e\u5f00\u653e\u5f0f\u624b\u672f<sup>[56]<\/sup>\u3002\u53e6\u4e00\u9879\u6c47\u603b\u4e866\u9879\u524d\u77bb\u6027\u968f\u673a\u5bf9\u7167\u7814\u7a76\u3001\u5171\u8ba1822\u4f8b\u60a3\u8005\u4e2a\u4f53\u6570\u636e\u7684\u5206\u6790\u7ed3\u679c\u63ed\u793a\uff0c\u5fae\u521b\u5916\u79d1\u7ec4\u4e0e\u5f00\u653e\u5f0f\u5916\u79d1\u7ec4\u5728\u672f\u540e3\u5e74OS\uff0856%\u6bd452%\uff0cP=0.54\uff09\u53caDFS\uff0854%\u6bd450%\uff0cP=0.38\uff09\u65b9\u9762\u76f8\u5f53\uff0c\u867d\u7136\u4e24\u8005\u5728\u6570\u636e\u7edf\u8ba1\u4e0a\u5448\u73b0\u7b49\u6548\u6027\uff0c\u4f46\u968f\u7740\u8fd1\u5e74\u6765\u5fae\u521b\u6280\u672f\u7684\u65e5\u81fb\u6210\u719f\u4e0e\u89c4\u8303\uff0c\u5fae\u521b\u7ec4\u7684\u6f5c\u5728\u751f\u5b58\u83b7\u76ca\u53ef\u80fd\u8fdb\u4e00\u6b65\u6269\u5927<sup>[57]<\/sup>\u3002\u5bf9\u4e8e\u4e0b\u6bb5\u98df\u7ba1\u764c\uff0c\u4e00\u9879\u5927\u578b\u591a\u4e2d\u5fc3\u968f\u673a\u5bf9\u7167\u7814\u7a76\u5df2\u7ecf\u8bc1\u5b9e\uff0c\u80f8\u8179\u8154\u955c\u8054\u5408\u6280\u672f\u76f8\u6bd4\u4f20\u7edf\u5f00\u653e\u624b\u672f\u5177\u6709\u66f4\u597d\u7684\u77ed\u671f\u6548\u679c<sup>[58]<\/sup>\u3002\u53e6\u4e00\u9879\u524d\u77bb\u6027\u968f\u673a\u5bf9\u7167\u7814\u7a76\u76843\u5e74\u968f\u8bbf\u7ed3\u679c\u663e\u793a\uff0c\u5fae\u521b\u624b\u672f\u4e0e\u5f00\u653e\u624b\u672f\u7684\u8fdc\u671f\u751f\u5b58\u7ed3\u679c\u5dee\u5f02\u65e0\u7edf\u8ba1\u5b66\u610f\u4e49\uff0c\u7efc\u5408\u77ed\u671f\u6548\u679c\u66f4\u52a0\u63a8\u8350\u98df\u7ba1\u764c\u5fae\u521b\u624b\u672f<sup>[59]<\/sup>\u3002\u6b64\u5916\uff0c\u4e00\u9879\u5305\u542b1 036\u4f8b\u60a3\u8005\u7684\u5168\u56fd\u591a\u4e2d\u5fc3\u56de\u987e\u6027\u975e\u968f\u673a\u5bf9\u7167\u7814\u7a76\u7ed3\u679c\u4e5f\u663e\u793a\uff0c\u5fae\u521b\u6280\u672f\u7684\u8fdc\u671f\u7597\u6548\u4e0e\u5f00\u653e\u98df\u7ba1\u5207\u9664\u8fdc\u671f\u751f\u5b58\u7ed3\u679c\u5dee\u5f02\u65e0\u7edf\u8ba1\u5b66\u610f\u4e49<sup>[60]<\/sup>\u3002\u4ea6\u6709\u4e00\u4e9b\u5bf9\u7167\u7814\u7a76\u7ed3\u679c\u663e\u793a\uff0c\u80f8\u8179\u8154\u955c\u5fae\u521b\u624b\u672f\u53ef\u51cf\u5c11AEG\u672f\u540e\u5e76\u53d1\u75c7\uff0c\u4e14\u5176\u8fdc\u671f\u7597\u6548\u4e0d\u4f4e\u4e8e\u3001\u751a\u81f3\u53ef\u80fd\u4f18\u4e8e\u5f00\u653e\u624b\u672f<sup>[61-63]<\/sup>\u3002\u56e0\u6b64\uff0c\u5efa\u8bae\u80f8\u8179\u8154\u955c\u8054\u5408\u624b\u672f\u53ef\u5728Siewert\u2160\u578b\u548c\u90e8\u5206Siewert\u2161\u578bAEG\u60a3\u8005\u4e2d\u5f00\u5c55\u3002<\/p>\n<p>\u63a8\u8350\u610f\u89c19. Siewert\u2161\u548c\u2162\u578bAEG\u8179\u8154\u955c\u624b\u672f\u6307\u5f81\uff1a\u672f\u524d\u5206\u671f\u4e3a\u2160\u671f\uff08cT1~2N0M0\uff09\u8005\u53ef\u8003\u8651\u884c\u8179\u8154\u955c\u624b\u672f\uff08\u8bc1\u636e\u7ea7\u522b\uff1a\u9ad8\uff0c\u63a8\u8350\u5f3a\u5ea6\uff1a\u5f3a\u63a8\u8350\uff09\uff1b\u672f\u524d\u5206\u671f\u4e3a\u2161~\u2162\u671f\u8005\uff0c\u8179\u8154\u955c\u624b\u672f\u53ef\u8003\u8651\u5728\u6709\u4e30\u5bcc\u8179\u8154\u955c\u624b\u672f\u7ecf\u9a8c\u7684\u533b\u5b66\u4e2d\u5fc3\u63a2\u7d22\u6027\u5730\u5f00\u5c55\uff08\u8bc1\u636e\u7ea7\u522b\uff1a\u4e2d\uff0c\u63a8\u8350\u5f3a\u5ea6\uff1a\u5f3a\u63a8\u8350\uff0c\u4e13\u5bb6\u7ec4\u8d5e\u540c\u7387\uff1a95.74%\uff09\u3002<\/p>\n<p>\u5faa\u8bc1\u533b\u5b66\u8bc1\u636e\uff1a\u8179\u8154\u955c\u5168\u80c3\u5207\u9664\u662f\u8fdb\u5c55\u671fSiewert\u2161\u3001\u2162\u578bAEG\u7684\u6807\u51c6\u624b\u672f\uff0c\u57fa\u4e8eJCOG1401\u7684\u7814\u7a76\u7ed3\u679c\uff0c\u65e5\u672c\u80c3\u764c\u6cbb\u7597\u6307\u5357\u7b2c6\u7248\u5df2\u7ecf\u5c06\u8179\u8154\u955c\u5168\u80c3\u5207\u9664\u5728\u2160\u671f\u80c3\u764c\u60a3\u8005\u4e2d\u4f5c\u4e3a\u5f31\u63a8\u8350<sup>[18,64]<\/sup>\u3002\u4e2d\u56fdCLASS\u204302\u7814\u7a76\u4ea6\u8bc1\u5b9e\u4e86\u8179\u8154\u955c\u5168\u80c3\u5207\u9664\u624b\u672f\u7684\u53ef\u884c\u6027\u548c\u5b89\u5168\u6027<sup>[65]<\/sup>\u3002CLASS\u204304\u591a\u4e2d\u5fc3\u8bd5\u9a8c\u7684\u77ed\u671f\u548c3\u5e74\u671f\u968f\u8bbf\u7ed3\u679c\u63ed\u793a\uff0c\u8179\u8154\u955c\u5168\u80c3\u5207\u9664\u5728\u5c40\u90e8\u8fdb\u5c55\u671f\u80c3\u4e0a\u90e8\u764c\u662f\u5b89\u5168\u548c\u6709\u6548\u7684\uff0c\u8fdb\u4e00\u6b65\u6269\u5c55\u4e86\u8179\u8154\u955c\u5168\u80c3\u5207\u9664\u7684\u9002\u5e94\u8bc1<sup>[66\u204367]<\/sup>\u3002\u65e5\u672c\u4e00\u9879\u57fa\u4e8e\u5168\u56fd\u6570\u636e\u7684\u56de\u987e\u6027\u7814\u7a76\uff0c\u5bf9\u6bd4\u548c\u5206\u6790\u4e86\u8179\u8154\u955c\u8f85\u52a9\u5168\u80c3\u5207\u9664\u548c\u5f00\u8179\u5168\u80c3\u5207\u9664\u7684\u5b89\u5168\u6027\uff0c\u7ed3\u679c\u663e\u793a\uff0c\u8179\u8154\u955c\u5168\u80c3\u5207\u9664\u662f\u5b89\u5168\u53ef\u884c\u7684<sup>[68]<\/sup>\u3002\u6765\u81ea\u56fd\u5185\u76844\u9879\u56de\u987e\u6027\u961f\u5217\u7814\u7a76\u4e5f\u80af\u5b9a\u4e86\u8179\u8154\u955c\u5168\u80c3\u5207\u9664\u7684\u5b89\u5168\u6027\u548c\u53ef\u884c\u6027<sup>[69\u204372]<\/sup>\u3002\u300a\u4e2d\u56fd\u8179\u8154\u955c\u80c3\u764c\u624b\u672f\u64cd\u4f5c\u6307\u5357\uff082023\u7248\uff09\u300b<sup>[73]<\/sup>\u548c\u300aSiewert\u2161\u578b\u98df\u7ba1\u80c3\u7ed3\u5408\u90e8\u817a\u764c\u8154\u955c\u624b\u672f\u6cbb\u7597\u4e2d\u56fd\u4e13\u5bb6\u5171\u8bc6\uff082023\u7248\uff09\u300b<sup>[21]<\/sup>\u5206\u522b\u5bf9\u8fdb\u5c55\u671f\u4e2d\u4e0a\u90e8\u80c3\u764c\u548cSiewert\u2161\u578bAEG\u7684\u8179\u8154\u955c\u624b\u672f\u9002\u5e94\u8bc1\u8fdb\u884c\u4e86\u660e\u786e\u63a8\u8350\u3002\u4f46\u662f\u5bf9\u4e8e\u8fdb\u5c55\u671fAEG\u884c\u8179\u8154\u955c\u624b\u672f\u5c1a\u7f3a\u5c11\u9ad8\u7ea7\u522b\u4e34\u5e8a\u8bc1\u636e\u548c\u8fdc\u671f\u968f\u8bbf\u7ed3\u679c\u7684\u652f\u6301\uff0c\u56e0\u6b64\uff0c\u672c\u5171\u8bc6\u5efa\u8bae\uff0c\u5bf9\u4e8e\u2160\u671fAEG\uff0c\u53ef\u884c\u8179\u8154\u955c\u624b\u672f\uff1b\u2161\u3001\u2162\u671fAEG\uff0c\u8179\u8154\u955c\u624b\u672f\u53ef\u63a2\u7d22\u6027\u5730\u5f00\u5c55\u3002<\/p>\n<p>\u63a8\u8350\u610f\u89c110.\u8179\u8154\u955c\u63a2\u67e5\u5728Siewert\u2161\u3001\u2162\u578bAEG\u3001\u5206\u671f\u4e3acT3~4\u671f\u7684\u75c5\u4f8b\u4e2d\u5e94\u7528\uff0c\u53ef\u8bc4\u4f30\u6709\u65e0\u8179\u819c\u79cd\u690d\uff08peritoneal implants,PI\uff09\uff0c\u4ee5\u8fdb\u4e00\u6b65\u51c6\u786e\u5206\u671f\u3001\u5236\u5b9a\u5408\u7406\u6cbb\u7597\u7b56\u7565\uff08\u8bc1\u636e\u7ea7\u522b\uff1a\u4e2d\uff0c\u63a8\u8350\u5f3a\u5ea6\uff1a\u5f3a\u63a8\u8350\uff0c\u4e13\u5bb6\u7ec4\u8d5e\u540c\u7387\uff1a100%\uff09\u3002<\/p>\n<p>\u5faa\u8bc1\u533b\u5b66\u8bc1\u636e\uff1a\u8179\u8154\u955c\u63a2\u67e5\u53c8\u79f0\u8bca\u65ad\u6027\u8179\u8154\u955c\uff0c\u6b64\u6280\u672f\u5728\u6d88\u5316\u7cfb\u7edf\u6076\u6027\u80bf\u7624\u4e2d\u5df2\u6709\u8f83\u5e7f\u6cdb\u7684\u4f7f\u7528\u3002\u4f46\u76ee\u524d\u56fd\u5185\u4e0d\u540c\u5730\u533a\u3001\u4e0d\u540c\u7ea7\u522b\u7684\u533b\u7597\u4e2d\u5fc3\u5bf9\u4e8e\u6d88\u5316\u7cfb\u7edf\u6076\u6027\u80bf\u7624\u8179\u8154\u955c\u63a2\u67e5\u7684\u63a5\u53d7\u7a0b\u5ea6\u5404\u6709\u4e0d\u4e00\u3002\u5168\u9762\u5730\u8fdb\u884c\u8179\u8154\u955c\u63a2\u67e5\u53ef\u4ee5\u51c6\u786e\u8bc4\u4f30\u8179\u819c\u8f6c\u79fb\u548c\u8179\u6c34\u8131\u843d\u7ec6\u80de\u60c5\u51b5\uff0c\u662f\u83b7\u5f97\u51c6\u786e\u80c3\u764c\u4e34\u5e8a\u5206\u671f\u7684\u5fc5\u8981\u624b\u6bb5\u4e4b\u4e00\uff0c\u5bf9\u4e8eP1\u548c\uff08\u6216\uff09CY1\u7684\u2163\u671f\u75c5\u4f8b\uff0c\u5176\u76f8\u5173\u6cbb\u7597\u7684\u6027\u8d28\u5747\u4e3a\u59d1\u606f\u6027\u7684\uff0c\u624b\u672f\u6cbb\u7597\u5e94\u662f\u5728\u8f6c\u5316\u6cbb\u7597\u6709\u6548\u7684\u57fa\u7840\u4e0a\u8003\u8651\uff0c\u6216\u8005\u56e0\u5e76\u53d1\u75c7\u800c\u884c\u59d1\u606f\u6027\u5207\u9664<sup>[74]<\/sup>\u3002\u8179\u819c\u79cd\u690d\u8f6c\u79fb\u662fSiewert\u2161\u3001\u2162\u578bAEG\u7684\u5e38\u89c1\u8fdc\u5904\u8f6c\u79fb\u65b9\u5f0f\u4e4b\u4e00\uff0c\u7b14\u8005\u5355\u4f4d\u7684\u4e00\u9879\u56de\u987e\u6027\u7814\u7a76\u663e\u793a\uff0c\u5bf9\u4e8e\u672f\u524d\u5206\u671f\u4e3acT4\u7684\u80c3\u764c\u60a3\u8005\uff0c\u5176\u5408\u5e76\u8179\u819c\u8f6c\u79fb\u548c\uff08\u6216\uff09\u8179\u6c34\u8131\u843d\u7ec6\u80de\u5b66\u9633\u6027\u7684\u6bd4\u4f8b\u9ad8\u8fbe27.4%\uff0c\u6545\u63d0\u51fa\u80c3\u764c\u8179\u8154\u955c\u63a2\u67e5\u56db\u6b65\u6cd5\u4ee5\u89c4\u8303\u8179\u8154\u955c\u63a2\u67e5\u64cd\u4f5c\u6d41\u7a0b\uff0c\u8fdb\u4e00\u6b65\u63a8\u5e7f\u8179\u8154\u955c\u63a2\u67e5\u5728\u80c3\u764c\u5916\u79d1\u8bca\u7597\u4e2d\u7684\u5e94\u7528<sup>[75\u204376]<\/sup>\u3002\u4e00\u9879\u7eb3\u51655\u9879\u56de\u987e\u6027\u7814\u7a76\u5171\u8ba1292\u4f8b\u5f71\u50cf\u5b66\u8bc4\u4f30\u4e3a\u9884\u671f\u53ef\u5207\u9664AEG\u75c5\u4f8b\u7684\u7cfb\u7edf\u8bc4\u4ef7\uff0c\u8ba4\u4e3a\u8179\u8154\u955c\u63a2\u67e5\u6709\u52a9\u4e8e\u8bca\u65ad\u9690\u533f\u6027\u8179\u819c\u79cd\u690d\u8f6c\u79fb\uff0c\u5e76\u4f7f\u8d85\u8fc710%\u7684AEG\u75c5\u4f8b\u6539\u53d8\u4e86\u6cbb\u7597\u65b9\u6848<sup>[77]<\/sup>\u3002<\/p>\n<p>\u56dbAEG\u7684\u5207\u9664\u8303\u56f4<\/p>\n<p>\u63a8\u8350\u610f\u89c111. 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cm\u548c\u6b8b\u80c3\u22651\/2\u7684Siewert\u2161\u578bAEG\u63a8\u8350\u7ecf\u8179\u8fd1\u7aef\u80c3\u5207\u9664\u3002Siewert\u2162\u578bAEG\u7684\u5207\u9664\u8303\u56f4\u53ef\u53c2\u8003\u80c3\u764c\u7684\u5904\u7406\u539f\u5219\uff0c\u6309\u7167\u65e5\u672c\u548c\u6211\u56fd\u80c3\u764c\u6cbb\u7597\u6307\u5357\uff0c\u5bf9\u4e8ecT1N0\u7684\u4e2d\u4e0a\u90e8\u764c\u53ef\u8003\u8651\u7ecf\u8179\u884c\u8fd1\u7aef\u80c3\u5207\u9664<sup>[17\u204318,20]<\/sup>\u3002\u4e00\u9879Meta\u5206\u6790\u6bd4\u8f83\u4e86Siewert\u2161\u3001\u2162\u578b\u884cAEG\u5168\u80c3\u5207\u9664\u6216\u8fd1\u7aef\u80c3\u5207\u9664\uff0c\u7eb3\u516512\u9879\u7814\u7a76\u51711 734\u4f8b\u75c5\u4f8b\uff0c\u7ed3\u679c\u53d1\u73b0\uff0c\u4e24\u7ec4\u672f\u540eOS\u5dee\u5f02\u65e0\u7edf\u8ba1\u5b66\u610f\u4e49\uff0c\u4f46\u8fd1\u7aef\u80c3\u5207\u9664\u5728\u6539\u5584\u8fdc\u671f\u8425\u517b\u72b6\u6001\u65b9\u9762\u5177\u6709\u4f18\u52bf<sup>[80]<\/sup>\u3002\u53e6\u4e00\u9879\u56fd\u9645\u591a\u4e2d\u5fc3\u56de\u987e\u6027\u7814\u7a76\u8bc1\u5b9e\uff0c\u8fd1\u7aef\u80c3\u5207\u9664\u672f\u540e\u60a3\u8005\u4f53\u8d28\u91cf\u4e0b\u964d\u3001\u8179\u6cfb\u548c\u503e\u5012\u7efc\u5408\u5f81\u7b49\u53d1\u751f\u7387\u663e\u8457\u4f4e\u4e8e\u5168\u80c3\u5207\u9664<sup>[81]<\/sup>\u3002<\/p>\n<p>\u5728\u8bc4\u4f30AEG\u5916\u79d1\u6cbb\u7597\u7b56\u7565\u7684\u7814\u7a76\u4e2d\uff0c\u4e00\u9879\u901a\u8fc7\u5bf910\u98793 217\u4f8b\u60a3\u8005\u961f\u5217\u7814\u7a76\u7684\u7cfb\u7edf\u8bc4\u4ef7\u5206\u6790\u53d1\u73b0\uff0c\u7ecf\u80f8\u98df\u7ba1\u5207\u9664+\u8fd1\u7aef\u80c3\u5207\u9664\u4e0e\u5168\u80c3\u5207\u9664\u672f\u4e24\u7ec4\u60a3\u8005\u7684R<sub>0<\/sub>\u5207\u9664\u7387\u3001\u5e76\u53d1\u75c7\u53d1\u751f\u7387\u3001\u672f\u540e30 d\u75c5\u6b7b\u7387\u53ca5\u5e74OS\u76f8\u4f3c\uff0c\u4f46\u5168\u80c3\u5207\u9664\u672f\u7ec4\u60a3\u8005\u672f\u540e6\u4e2a\u6708\u7684\u751f\u6d3b\u8d28\u91cf\u66f4\u4f73<sup>[82]<\/sup>\u3002\u53e6\u4e00\u9879\u57fa\u4e8e9 594\u4f8bSiewert\u2161\u578bAEG\u7684\u4e34\u5e8a\u7814\u7a76\uff0c\u5bf9\u4e24\u79cd\u624b\u672f\u7684\u8fdc\u671f\u9884\u540e\u8fdb\u884c\u4e86\u6bd4\u8f83\u3002\u901a\u8fc7\u503e\u5411\u8bc4\u5206\u5339\u914d\u8c03\u6574\u60a3\u8005\u7279\u5f81\u540e\uff0c\u53d1\u73b0\u7ecf\u80f8\u98df\u7ba1\u5207\u9664+\u8fd1\u7aef\u80c3\u5207\u9664\u7684\u60a3\u8005\u5728\u603b\u751f\u5b58\u671f\u548c5\u5e74OS\u65b9\u9762\uff0c\u4f18\u4e8e\u63a5\u53d7\u5168\u80c3\u5207\u9664\u672f\u7684\u60a3\u8005\uff08\u4e2d\u4f4d\u751f\u5b58\u671f\u5206\u522b\u4e3a68\u4e2a\u6708\u6bd451\u4e2a\u6708\uff0c5\u5e74OS\u5206\u522b\u4e3a53%\u6bd447%\uff09\uff0c\u4e14\u4e24\u79cd\u624b\u672f\u5728\u6dcb\u5df4\u7ed3\u6e05\u626b\u6570\u91cf\u3001\u4f4f\u9662\u65f6\u957f\u548c90 d\u75c5\u6b7b\u7387\u65b9\u9762\u76f8\u4f3c<sup>[83]<\/sup>\u3002\u4f46\u8fd1\u671f\u4e00\u9879\u7eb3\u5165\u4e8611\u9879\u7814\u7a76\uff0818 585\u4f8b\u60a3\u8005\uff09\u7684\u7cfb\u7edf\u8bc4\u4ef7\u53d1\u73b0\uff0c\u98df\u7ba1\u5207\u9664\u548c\u5168\u80c3\u5207\u9664\u672f\u7684\u4e24\u79cd\u624b\u672f\u5728\u672f\u540e\u543b\u5408\u53e3\u6f0f\u548cR<sub>0<\/sub>\u5207\u9664\u7387\u4e0a\u5dee\u5f02\u65e0\u7edf\u8ba1\u5b66\u610f\u4e49\uff0c\u4f46\u5168\u80c3\u5207\u9664\u672f\u5728\u672f\u540e30 d\u75c5\u6b7b\u7387\u548c5\u5e74OS\u65b9\u9762\u8868\u73b0\u66f4\u4f18<sup>[40]<\/sup>\u3002\u4ee5\u4e0a\u7ed3\u679c\u63d0\u793a\uff0c\u7ecf\u80f8\u98df\u7ba1\u5207\u9664+\u8fd1\u7aef\u80c3\u5207\u9664\u5728Siewert\u2161\u578b\u4e0a\u7684\u5e94\u7528\u5c1a\u5b58\u4e89\u8bae\uff0c\u4f46\u662f\u672c\u5171\u8bc6\u5efa\u8bae\uff0c\u7ecf\u80f8\u98df\u7ba1\u5207\u9664+\u8fd1\u7aef\u80c3\u5207\u9664\u662fSiewert\u2160\u578bAEG\u7684\u9996\u9009\u6cbb\u7597\u65b9\u5f0f\uff0c\u800c\u90e8\u5206\u80bf\u7624\u76f4\u5f84\u8f83\u5927\u3001\u4e14\u98df\u7ba1\u53d7\u7d2f\u957f\u5ea6\u9ad8\u7684Siewert\u2161\u578bAEG\u4e5f\u53ef\u4ee5\u9009\u62e9\u6027\u5730\u5f00\u5c55\u3002\u65e5\u672c\u4e00\u9879\u7814\u7a76\u7eb3\u51657\u4e2a\u4e2d\u5fc3\u5171288\u4f8bR<sub>0<\/sub>\u5207\u9664\u7684Siewert\u2161\u578bAEG\u60a3\u8005\u53d1\u73b0\uff0c\u5f53\u80bf\u7624\u8fdc\u7aef\u8dddEGJ\u22643 cm\u65f6\uff0c\u80c3\u5927\u5f2f\u53ca\u5e7d\u95e8\u533a\u57df\u6dcb\u5df4\u7ed3\u8f6c\u79fb\u7387&lt;2.2%\uff1b\u5f53\u80bf\u7624\u8fdc\u7aef\u8dddEGJ&gt;5 cm\u65f6\uff0c\u8be5\u533a\u57df\u6dcb\u5df4\u7ed3\u8f6c\u79fb\u7387\u8fbe20%<sup>[84]<\/sup>\u3002\u56e0\u6b64\uff0c\u5efa\u8bae\u9009\u62e9\u5168\u80c3\u5207\u9664\u6216\u8fd1\u7aef\u80c3\u5207\u9664\u65f6\u5e94\u8003\u8651\u80bf\u7624\u8fdc\u7aef\u8dddEGJ\u7684\u8ddd\u79bb\u3002<\/p>\n<p>\u4e94\u98df\u7ba1\u5207\u7f18\u4e0eAEG\u80bf\u7624\u4e0a\u7f18\u7684\u8ddd\u79bb<\/p>\n<p>\u63a8\u8350\u610f\u89c114.\u5bf9\u4e8e\u5206\u671f\u4e3acT1\u7684Siewert\u2161\u3001\u2162\u578bAEG\uff0c\u5728\u4f53\u98df\u7ba1\u5207\u7f18\u8ddd\u79bb\u5efa\u8bae\u22651.5 cm\uff08\u80bf\u7624\u76f4\u5f84\u22654 cm\u8005\uff0c\u98df\u7ba1\u5207\u7f18\u8ddd\u79bb\u5efa\u8bae\u22652 cm\uff09\uff08\u8bc1\u636e\u7ea7\u522b\uff1a\u9ad8\uff0c\u63a8\u8350\u5f3a\u5ea6\uff1a\u5f3a\u63a8\u8350\uff0c\u4e13\u5bb6\u7ec4\u8d5e\u540c\u7387\uff1a82.98%\uff09\u3002<\/p>\n<p>\u63a8\u8350\u610f\u89c115.\u5206\u671fcT2\u53ca\u4ee5\u4e0a\u7684Siewert\u2161\u3001\u2162\u578bAEG\uff0c\u5728\u4f53\u98df\u7ba1\u5207\u7f18\u8ddd\u79bb\u63a8\u8350\u22653 cm\uff0c\u5e76\u5efa\u8bae\u672f\u4e2d\u5feb\u901f\u51b0\u51bb\u5207\u7247\u68c0\u67e5\uff08\u8bc1\u636e\u7ea7\u522b\uff1a\u9ad8\uff0c\u63a8\u8350\u5f3a\u5ea6\uff1a\u5f3a\u63a8\u8350\uff0c\u4e13\u5bb6\u7ec4\u8d5e\u540c\u7387\uff1a91.49%\uff09\u3002<\/p>\n<p>\u63a8\u8350\u610f\u89c116\uff1a\u672f\u4e2d\u51b0\u51bb\u75c5\u7406\u68c0\u67e5\u5bf9\u4fdd\u8bc1\u98df\u7ba1\u5207\u7f18\u548c\u80c3\u5207\u7f18\u7684\u80bf\u7624\u5b66\u5b89\u5168\u6027\u6709\u91cd\u8981\u4ef7\u503c\uff0c\u5c40\u90e8\u75c5\u671f\u504f\u665a\u3001\u6216\u7ecf\u8179\u5207\u9664\u7684AEG\uff0c\u5efa\u8bae\u672f\u4e2d\u8fdb\u884c\u4e0a\u5207\u7f18\u7684\u672f\u4e2d\u51b0\u51bb\u75c5\u7406\u68c0\u67e5\uff08\u8bc1\u636e\u7ea7\u522b\uff1a\u4e2d\uff0c\u63a8\u8350\u5f3a\u5ea6\uff1a\u5f3a\u63a8\u8350\uff0c\u4e13\u5bb6\u7ec4\u8d5e\u540c\u7387\uff1a93.62%\uff09\u3002<\/p>\n<p>\u5faa\u8bc1\u533b\u5b66\u8bc1\u636e\uff1aAEG\u8fd1\u7aef\u5207\u7f18\u9633\u6027\u4f9d\u7136\u662f\u5f53\u524d\u5916\u79d1\u6cbb\u7597\u4e2d\u65e0\u6cd5\u56de\u907f\u7684\u4e00\u4e2a\u91cd\u8981\u95ee\u9898\u3002\u98df\u7ba1\u5207\u7f18\u9633\u6027\u8f83\u5207\u7f18\u9634\u6027\u5c06\u660e\u663e\u964d\u4f4e\u8fdc\u671f\u751f\u5b58\u7387\uff0c\u4e2d\u4f4d\u751f\u5b58\u65f6\u95f4\u4e5f\u660e\u663e\u7f29\u77ed\uff0811.1\u4e2a\u6708\u6bd436.3\u4e2a\u6708\uff09<sup>[85]<\/sup>\u3002\u8fd1\u5e74\u6765\u7684\u7814\u7a76\u8868\u660e\uff0c\u5207\u7f18\u8ddd\u79bb\u5e94\u6839\u636e\u80bf\u7624\u5206\u671f\u3001\u98df\u7ba1\u53d7\u7d2f\u957f\u5ea6\u548c\u80bf\u7624\u5927\u5c0f\u5171\u540c\u51b3\u5b9a\u3002\u4e00\u9879\u610f\u5927\u5229\u591a\u4e2d\u5fc3\u7814\u7a76\u663e\u793a\uff0c\u5207\u7f18\u8ddd\u79bb\u22642 cm\u662fcT1\u671fAEG\u5207\u7f18\u9633\u6027\u7684\u72ec\u7acb\u5371\u9669\u56e0\u7d20\uff1b\u5207\u7f18\u8ddd\u79bb\u22643 cm\u662fcT2~4\u671fAEG\u5207\u7f18\u9633\u6027\u7684\u72ec\u7acb\u5371\u9669\u56e0\u7d20<sup>[86]<\/sup>\u3002\u65e5\u672c\u7684\u4e00\u9879\u7814\u7a76\u663e\u793a\uff0c\u5bf9\u4e8ecT1\u671f\u6216\u80bf\u7624\u76f4\u5f84\u22644 cm\u7684Siewert\u2161\u578bAEG\uff0c\u80bf\u7624\u75c5\u7406\u6027\u8fb9\u754c\u5411\u98df\u7ba1\u8fd1\u7aef\u6d78\u6da6\u7684\u8ddd\u79bb\u6700\u5927\u4e0d\u8d85\u8fc71.5 cm\uff1b\u5bf9\u4e8e\u76f4\u5f84&gt;4 cm\u6216cT2\u671f\u4ee5\u4e0a\u7684AEG\uff0c\u8be5\u8ddd\u79bb\u4e0d\u8d85\u8fc72.5 cm<sup>[87]<\/sup>\u3002\u672c\u5171\u8bc6\u5efa\u8bae\uff1a\u5bf9\u4e8ecT1\u671fSiewert\u2161\u3001\u2162\u578bAEG\uff0c\u98df\u7ba1\u5207\u7f18\u8ddd\u80bf\u7624\u4e0a\u7f18\u63a8\u83501.5 cm\u4ee5\u4e0a\uff1b\u5bf9\u4e8ecT2\u671f\u53ca\u4ee5\u4e0a\u5206\u671f\u7684Siewert\u2161\u3001\u2162\u578bAEG\uff0c\u98df\u7ba1\u5207\u7f18\u8ddd\u80bf\u7624\u4e0a\u7f18\u63a8\u83503 cm\u4ee5\u4e0a\u3002<\/p>\n<p>\u65e0\u8bba\u98df\u7ba1\u5207\u7f18\u6216\u662f\u80c3\u5207\u7f18\u764c\u6b8b\u7559\uff0c\u5747\u662f\u4e0d\u826f\u9884\u540e\u56e0\u7d20\u3002\u5c24\u5176\u98df\u7ba1\u5207\u7f18\u80bf\u7624\u6b8b\u7559\u53d1\u751f\u7387\u8f83\u80c3\u5207\u7f18\u66f4\u9ad8\u3002\u4e3a\u4fdd\u8bc1\u4e0a\u5207\u7f18\u9634\u6027\uff0c\u901a\u5e38\u5efa\u8bae\u884c\u672f\u4e2d\u5feb\u901f\u51b0\u51bb\u75c5\u7406\u5207\u7247\u68c0\u67e5\uff0c\u5176\u5177\u6709\u9ad8\u654f\u611f\u5ea6\u548c\u7279\u5f02\u6027<sup>[88]<\/sup>\u3002\u65e5\u672c\u80c3\u764c\u6cbb\u7597\u6307\u5357\u6307\u51fa\uff0c\u5bf9\u4e8e\u98df\u7ba1\u53d7\u7d2f\u7684\u80bf\u7624\uff0c\u5e76\u4e0d\u5f3a\u5236\u8981\u6c42\u5207\u7f18\u8ddd\u79bb\u22655 cm\uff0c\u4f46\u9700\u8981\u901a\u8fc7\u672f\u4e2d\u51b0\u51bb\u75c5\u7406\u5207\u7247\u68c0\u67e5\u8bc1\u5b9e\u5207\u7f18\u9634\u6027<sup>[17\u204318]<\/sup>\u3002\u56e0\u6b64\uff0c\u4e3a\u4fdd\u8bc1R<sub>0<\/sub>\u5207\u9664\u7387\uff0c\u5e94\u79ef\u6781\u5f00\u5c55\u672f\u4e2d\u5feb\u901f\u51b0\u51bb\u5207\u7f18\u75c5\u7406\u68c0\u67e5\uff0c\u4ee5\u964d\u4f4e\u672f\u540e\u5207\u7f18\u9633\u6027\u5f71\u54cd\u9884\u540e\u7684\u6982\u7387\u3002\u4f46\u8003\u8651\u5230\u56fd\u5185\u4e0d\u540c\u5730\u533a\u3001\u4e0d\u540c\u533b\u9662\u7684\u75c5\u7406\u79d1\u6761\u4ef6\u53c2\u5dee\u4e0d\u9f50\uff0c\u90e8\u5206\u533b\u9662\u5b58\u5728\u672f\u4e2d\u5207\u7f18\u5feb\u901f\u51b0\u51bb\u75c5\u7406\u5207\u7247\u68c0\u67e5\u7ed3\u679c\u7b49\u5f85\u65f6\u95f4\u8f83\u957f\u7b49\u56e0\u7d20\uff0c\u5bf9\u4e8e\u662f\u5426\u505a\u5207\u7f18\u5feb\u901f\u51b0\u51bb\u75c5\u7406\u68c0\u67e5\u4e0d\u505a\u5f3a\u884c\u5e38\u89c4\u8981\u6c42\uff0c\u672c\u5171\u8bc6\u5efa\u8bae\uff1a\u5bf9\u65e9\u671f\u6216\u80bf\u7624\u76f4\u5f84\u8f83\u5c0f\u7684AEG\uff0c\u672f\u4e2d\u5e94\u6839\u636e\u80bf\u7624\u8fb9\u7f18\u4e0e\u5207\u7f18\u8ddd\u79bb\u914c\u60c5\u5f00\u5c55\uff1b\u5bf9\u4e8eAEG\u5c40\u90e8\u75c5\u671f\u504f\u665a\u4ee5\u53ca\u7ecf\u8179\u5207\u9664\u7684\u75c5\u4f8b\uff0c\u987b\u8fdb\u884c\u672f\u4e2d\u5207\u7f18\u51b0\u51bb\u75c5\u7406\u68c0\u67e5\uff0c\u4ee5\u786e\u4fdd\u8fd1\u7aef\u98df\u7ba1\u5207\u7f18\u7684\u5b89\u5168\u6027\u3002<\/p>\n<p>\u516dAEG\u7684\u6dcb\u5df4\u7ed3\u5206\u7ec4\u53ca\u6e05\u626b\u89c4\u8303<\/p>\n<p>\u63a8\u8350\u610f\u89c117.Siewert\u2160\u578bAEG\u6309\u7167\u98df\u7ba1\u764c\u8fdb\u884c\u6dcb\u5df4\u7ed3\u5206\u7ec4\uff1bSiewert\u2161\u3001\u2162\u578bAEG\u5219\u6309\u7167\u80c3\u764c\u8fdb\u884c\u6dcb\u5df4\u7ed3\u5206\u7ec4\uff08\u8bc1\u636e\u7ea7\u522b\uff1a\u9ad8\uff0c\u63a8\u8350\u5f3a\u5ea6\uff1a\u5f3a\u63a8\u8350\uff0c\u4e13\u5bb6\u7ec4\u8d5e\u540c\u7387\uff1a93.62%\uff09\u3002<\/p>\n<p>\u5faa\u8bc1\u533b\u5b66\u8bc1\u636e\uff1a\u4e3a\u4e86\u89c4\u8303\u63cf\u8ff0\uff0cAJCC\/UICC\u7b2c8\u7248\u4e2d\u98df\u7ba1\u764c\u53ca\u80c3\u764c\u7ae0\u8282\u5747\u5df2\u660e\u786e\u8bf4\u660e\uff0c\u82e5\u80bf\u7624\u4e2d\u5fc3\u4f4d\u4e8eEGJ\u4ee5\u4e0b2 cm\u5185\uff08\u542b2 cm\uff09\u5e76\u4fb5\u72afEGJ\uff0c\u6309\u98df\u7ba1\u764c\u8fdb\u884c\u5206\u671f\uff1b\u82e5\u80bf\u7624\u4e2d\u5fc3\u4f4d\u4e8eEGJ\u4ee5\u4e0b2 cm\u4ee5\u8fdc\u5e76\u4fb5\u72afEGJ\uff0c\u5219\u53c2\u7167\u80c3\u764c\u6dcb\u5df4\u7ed3\u5206\u7ec4\u3002\u6240\u4ee5Siewert\u2160\u578b\u7684\u6dcb\u5df4\u7ed3\u5206\u7ec4\u53c2\u7167\u98df\u7ba1\u764c\uff0cSiewert\u2162\u578b\u7684\u6dcb\u5df4\u7ed3\u5206\u7ec4\u53c2\u7167\u80c3\u764c\u3002\u4f46\u662f\u53c2\u71672022\u5e74\u53d1\u5e03\u7684\u7b2c12\u7248\u65e5\u672c\u300a\u98df\u7ba1\u764c\u5904\u7406\u89c4\u7ea6\u300b\uff0cSiewert\u2161\u578bAEG\u7684\u6dcb\u5df4\u7ed3\u5206\u7ec4\u5e94\u53c2\u7167\u80c3\u764c<sup>[38]<\/sup>\u3002\u8fd9\u4e00\u70b9\u76ee\u524d\u5c1a\u5b58\u4e89\u8bae\uff0c\u5efa\u8bae\u5f00\u5c55\u76f8\u5173\u7684\u591a\u4e2d\u5fc3\u4e34\u5e8a\u7814\u7a76\u3002<\/p>\n<p>\uff08\u4e00\uff09AEG\u80f8\u90e8\u6dcb\u5df4\u7ed3\u6e05\u626b\u89c4\u8303<\/p>\n<p>\u63a8\u8350\u610f\u89c118.Siewert\u2160\u578bAEG\u7684\u80f8\u90e8\u6dcb\u5df4\u7ed3\u6e05\u626b\u5e94\u53c2\u7167\u4e2d\u4e0b\u6bb5\u98df\u7ba1\u764c\u7684\u5904\u7406\u539f\u5219\uff0c\u884c\u89c4\u8303\u7684\u7eb5\u9694\u6dcb\u5df4\u7ed3\u6e05\u626b\uff08\u8bc1\u636e\u7ea7\u522b\uff1a\u9ad8\uff0c\u63a8\u8350\u5f3a\u5ea6\uff1a\u5f3a\u63a8\u8350\uff0c\u4e13\u5bb6\u7ec4\u8d5e\u540c\u7387\uff1a97.87%\uff09\u3002<\/p>\n<p>\u63a8\u8350\u610f\u89c119.Siewert\u2161\u578bAEG\uff0c\u82e5\u98df\u7ba1\u53d7\u7d2f\u957f\u5ea6&lt;2 cm\uff0c\u65e0\u9700\u884c\u4e0b\u7eb5\u9694\u6dcb\u5df4\u7ed3\u6e05\u626b\uff1b\u82e5\u98df\u7ba1\u53d7\u7d2f\u957f\u5ea6\u4e3a2~4 cm\uff0c\u5219\u884c\u4e0b\u7eb5\u9694\u6dcb\u5df4\u7ed3\u6e05\u626b\uff08\u80c3\u764c\u6dcb\u5df4\u7ed3\u5206\u7ec4\uff1aNo.110\u3001No.111\u548cNo.112\uff09\uff1b\u98df\u7ba1\u53d7\u7d2f\u957f\u5ea6&gt;4 cm\u8005\uff0c\u6309\u7167Siewert\u2160\u578b\u7684\u5904\u7406\u539f\u5219\uff0c\u884c\u89c4\u8303\u7684\u7eb5\u9694\u6dcb\u5df4\u7ed3\u6e05\u626b\uff08\u8bc1\u636e\u7ea7\u522b\uff1a\u4e2d\uff0c\u63a8\u8350\u5f3a\u5ea6\uff1a\u5f3a\u63a8\u8350\uff0c\u4e13\u5bb6\u7ec4\u8d5e\u540c\u7387\uff1a95.74%\uff09\u3002<\/p>\n<p>\u63a8\u8350\u610f\u89c120.Siewert\u2162\u578bAEG\u5e94\u53c2\u7167\u80c3\u764c\u6dcb\u5df4\u7ed3\u6e05\u626b\u89c4\u8303\u8fdb\u884c\uff0c\u5e76\u6839\u636e\u80bf\u7624\u4fb5\u72af\u98df\u7ba1\u4e0e\u5426\uff0c\u51b3\u5b9a\u662f\u5426\u8fdb\u884c\u4e0b\u7eb5\u9694\u6dcb\u5df4\u7ed3\u6e05\u626b\uff08\u8bc1\u636e\u7ea7\u522b\uff1a\u9ad8\uff0c\u63a8\u8350\u5f3a\u5ea6\uff1a\u5f3a\u63a8\u8350\uff0c\u4e13\u5bb6\u7ec4\u8d5e\u540c\u7387\uff1a97.87%\uff09\u3002<\/p>\n<p>\u5faa\u8bc1\u533b\u5b66\u8bc1\u636e\uff1a\u6dcb\u5df4\u7ed3\u8f6c\u79fb\u662fAEG\u5e38\u89c1\u7684\u8f6c\u79fb\u9014\u5f84\uff0c\u89c4\u8303\u5f7b\u5e95\u7684\u6dcb\u5df4\u7ed3\u6e05\u626b\u662f\u4fdd\u969c\u624b\u672f\u8fdc\u671f\u7597\u6548\u81f3\u5173\u91cd\u8981\u7684\u73af\u8282\u3002AEG\u7531\u4e8e\u4f4d\u7f6e\u7279\u6b8a\uff0c\u5176\u6dcb\u5df4\u7ed3\u8f6c\u79fb\u65b9\u5f0f\u53ef\u4ee5\u5206\u522b\u5411\u80f8\u90e8\u548c\u8179\u90e8\u8f6c\u79fb\u3002\u7eb5\u9694\u6dcb\u5df4\u7ed3\u8f6c\u79fb\u7387\u5728Siewert\u2160\u3001\u2161\u3001\u2162\u578bAEG\u4e2d\u5206\u522b\u53ef\u8fbe46.2%~65.0%\u300112.0%~29.5%\u548c6.0%~9.3%<sup>[41,89\u204390]<\/sup>\u3002\u7814\u7a76\u8868\u660e\uff0c\u7eb5\u9694\u6dcb\u5df4\u7ed3\u8f6c\u79fb\u7387\u4e0e\u80bf\u7624T\u5206\u671f\u548c\u98df\u7ba1\u53d7\u7d2f\u957f\u5ea6\u5bc6\u5207\u76f8\u5173\uff0c\u98df\u7ba1\u53d7\u7d2f\u957f\u5ea6\u662f\u7eb5\u9694\u6dcb\u5df4\u7ed3\u8f6c\u79fb\u7684\u72ec\u7acb\u5371\u9669\u56e0\u7d20<sup>[91\u204392]<\/sup>\u3002\u4e00\u9879\u591a\u4e2d\u5fc3\u56de\u987e\u6027\u7814\u7a76\u7eb3\u5165315\u4f8b\u8fdb\u5c55\u671fSiewert\u2161\u578bAEG\u60a3\u8005\uff0c\u5bf9\u4e0a\u3001\u4e2d\u3001\u4e0b\u7eb5\u9694\u6dcb\u5df4\u7ed3\u8f6c\u79fb\u7387\u8fdb\u884c\u4e86\u7cfb\u7edf\u7814\u7a76\uff1a\u80bf\u7624\u4fb5\u72af\u98df\u7ba1&gt;2 cm\u65f6\uff0c\u4e0b\u7eb5\u9694\u6dcb\u5df4\u7ed3\u8f6c\u79fb\u7387\u589e\u52a0\uff0c\u98df\u7ba1\u53d7\u7d2f\u957f\u5ea6&gt;3 cm\u65f6\uff0c\u4e0a\u3001\u4e2d\u7eb5\u9694\u6dcb\u5df4\u7ed3\u8f6c\u79fb\u7387\u660e\u663e\u5347\u9ad8\u81f313.9%\u548c19.4%<sup>[91]<\/sup>\u3002\u4e00\u9879\u7eb3\u51652 807\u4f8b\u80bf\u7624\u76f4\u5f84&lt;4 cm\u7684AEG\u75c5\u4f8b\u7814\u7a76\u663e\u793a\uff1a\u80bf\u7624\u4e2d\u5fc3\u504f\u5411\u98df\u7ba1\u4fa7\u7684AEG\u75c5\u4f8b\u4e2d\uff0cT1\u671fNo.110\u3001No.111\u548cNo.112\u7684\u6dcb\u5df4\u7ed3\u8f6c\u79fb\u7387\u5206\u522b\u4e3a0.5%\u30010.3%\u548c0.5%\uff0cT2\u671f\u75c5\u4f8b\u5219\u5206\u522b\u4e3a5.1%\u30011.7%\u548c1.3%\uff0cT3~4\u671f\u75c5\u4f8b\u987b\u91cd\u89c6No.106r\u3001No.108\u3001No.109\u3001No.110\u548cNo.111\u7eb5\u9694\u6dcb\u5df4\u7ed3\u7684\u8f6c\u79fb\uff1b\u800c\u80bf\u7624\u504f\u5411\u80c3\u4fa7\u7684AEG\uff0c\u5176\u4e0b\u7eb5\u9694\u6dcb\u5df4\u7ed3\u8f6c\u79fb\u7387\u5747\u4f4e\u4e8e1.0%<sup>[92]<\/sup>\u3002\u53e6\u6709\u4e00\u9879\u7814\u7a76\u8868\u660e\uff0cSiewert\u2161\u578bAEG\uff0c\u4e0b\u7eb5\u9694\u6dcb\u5df4\u7ed3\u603b\u4f53\u8f6c\u79fb\u7387\u4e3a13.7%\uff1b\u5f53\u98df\u7ba1\u53d7\u7d2f\u957f\u5ea6&lt;2.5 cm\u65f6\uff0c\u4e0b\u7eb5\u9694\u6dcb\u5df4\u7ed3\u8f6c\u79fb\u7387\u4e0b\u964d\u81f39.3%\uff1b\u5f53\u98df\u7ba1\u53d7\u7d2f\u957f\u5ea6\u22652.5 cm\u65f6\uff0c\u4e0b\u7eb5\u9694\u6dcb\u5df4\u7ed3\u8f6c\u79fb\u7387\u9ad8\u8fbe24.0%<sup>[93]<\/sup>\u3002\u4e00\u9879\u65e5\u672c\u7684\u524d\u77bb\u6027\u591a\u4e2d\u5fc3\u7814\u7a76\uff0c\u7cfb\u7edf\u9610\u8ff0\u4e86AEG\u98df\u7ba1\u53d7\u7d2f\u957f\u5ea6\u4e0e\u4e0b\u7eb5\u9694\u6dcb\u5df4\u7ed3\u8f6c\u79fb\u7387\u7684\u76f8\u5173\u6027\uff1a\u98df\u7ba1\u53d7\u7d2f\u957f\u5ea6\u4e3a2.0~3.0 cm\u30013.0~4.0 cm\u548c&gt;4.0 cm\u65f6\uff0c\u5176\u5bf9\u5e94\u7684No.110\u6dcb\u5df4\u7ed3\u8f6c\u79fb\u7387\u5206\u522b\u4e3a10.8%\u300120.8%\u548c28.6%\uff1b\u5f53\u98df\u7ba1\u53d7\u7d2f\u957f\u5ea6&lt;2 cm\u65f6\uff0c\u4e0b\u7eb5\u9694\u6dcb\u5df4\u7ed3\u8f6c\u79fb\u7387\u504f\u4f4e\uff0cNo.110\u3001No.111\u548cNo.112\u7684\u8f6c\u79fb\u7387\u5206\u522b\u4e3a6.4%\u30012.2%\u548c2.2%\uff1b\u63d0\u793a\uff0c\u5f53\u98df\u7ba1\u53d7\u7d2f\u957f\u5ea6\u22652 cm\u65f6\uff0c\u4e0b\u7eb5\u9694No.110\u6dcb\u5df4\u7ed3\u5e94\u4f5c\u4e3a\u5e38\u89c4\u6e05\u626b<sup>[94]<\/sup>\u3002\u6b64\u5916\u8be5\u7814\u7a76\u8fd8\u53d1\u73b0\uff0c\u867d\u7136\u4e0a\u3001\u4e2d\u7eb5\u9694\u6dcb\u5df4\u7ed3\u603b\u4f53\u8f6c\u79fb\u7387\u8f83\u4f4e\uff0c\u4f46\u5f53\u98df\u7ba1\u53d7\u7d2f\u957f\u5ea6\u22654 cm\u65f6\uff0c\u4e0a\u3001\u4e2d\u7eb5\u9694\u6dcb\u5df4\u7ed3\u8f6c\u79fb\u7387\u4f1a\u589e\u9ad8\uff0c\u5176\u4e2dNo.106recR\u3001No.107\u3001No.108\u548cNo.109L\u6dcb\u5df4\u7ed3\u8f6c\u79fb\u53d1\u751f\u7387\u5206\u522b\u4e3a10.7%\u30017.1%\u30017.1%\u548c7.1%<sup>[94]<\/sup>\u3002\u8be5\u524d\u77bb\u6027\u7814\u7a76\u662f\u8fc4\u4eca\u5173\u4e8eAEG\u6dcb\u5df4\u7ed3\u6e05\u626b\u7684\u6700\u9ad8\u7ea7\u522b\u5faa\u8bc1\u533b\u5b66\u8bc1\u636e\u3002\u7b2c12\u7248\u65e5\u672c\u300a\u98df\u7ba1\u764c\u5904\u7406\u89c4\u7ea6\u300b\u660e\u786e\u6307\u51fa\uff0c\u5bf9\u4e8e\u98df\u7ba1\u4fb5\u72af\u8ddd\u79bb&gt;4 cm\u7684AEG\uff0c\u63a8\u8350\u6e05\u626bNo.106r\u548c\u4e2d\u3001\u4e0b\u7eb5\u9694\u6dcb\u5df4\u7ed3<sup>[38]<\/sup>\u3002<\/p>\n<p>\u7efc\u4e0a\u6240\u8ff0\uff0c\u672c\u5171\u8bc6\u63a8\u8350\uff1aSiewert\u2160\u578bAEG\u7684\u80f8\u90e8\u6dcb\u5df4\u7ed3\u6e05\u626b\uff0c\u5e94\u53c2\u7167\u4e2d\u4e0b\u6bb5\u98df\u7ba1\u764c\u8fdb\u884c\u5f7b\u5e95\u7684\u7eb5\u9694\u6dcb\u5df4\u7ed3\u6e05\u626b\uff0c\u5305\u62ec\u4e0a\u7eb5\u9694\u5de6\u53f3\u5589\u8fd4\u795e\u7ecf\u65c1\u6dcb\u5df4\u7ed3\uff082R\u30012L\uff09\u3002Siewert\u2161\u578bAEG\uff0c\u98df\u7ba1\u53d7\u7d2f\u957f\u5ea6&gt;4 cm\u65f6\uff0c\u9700\u8fdb\u884c\u89c4\u8303\u7684\u7eb5\u9694\u6dcb\u5df4\u7ed3\u6e05\u626b\uff1b\u98df\u7ba1\u53d7\u7d2f\u957f\u5ea62~4 cm\u65f6\uff0c\u987b\u884c\u4e0b\u7eb5\u9694\u6dcb\u5df4\u7ed3\u6e05\u626b\uff0c\u81f3\u5c11\u5b8c\u6210No.110\u7684\u6e05\u626b\uff1b\u800c\u98df\u7ba1\u53d7\u7d2f&lt;2 cm\u65f6\uff0c\u4e0d\u63a8\u8350\u6e05\u626b\u4e0b\u7eb5\u9694\u6dcb\u5df4\u7ed3\u3002Siewert\u2162\u578bAEG\uff0c\u5e94\u6839\u636e\u80bf\u7624\u4fb5\u72af\u98df\u7ba1\u4e0e\u5426\uff0c\u51b3\u5b9a\u662f\u5426\u8fdb\u884c\u4e0b\u7eb5\u9694\u6dcb\u5df4\u7ed3\u6e05\u626b\u3002<\/p>\n<p>\u98df\u7ba1\u764c\u6dcb\u5df4\u7ed3\u6e05\u626b\u5206\u4e3a\u4e0a\u7eb5\u9694\u533a\u3001\u4e0b\u7eb5\u9694\u533a\u548c\u8179\u533a\uff0c\u76f8\u5173\u5206\u7ec4\u89c1\u88682\u548c\u56fe2<sup>[95]<\/sup>\u3002<\/p>\n<\/p>\n<p>\uff08\u4e8c\uff09AEG\u8179\u90e8\u6dcb\u5df4\u7ed3\u6e05\u626b\u89c4\u8303<\/p>\n<p>\u63a8\u8350\u610f\u89c121.Siewert\u2160\u578bAEG\uff1a\u53c2\u7167\u4e0b\u6bb5\u98df\u7ba1\u764c\u5904\u7406\u539f\u5219\uff0c\u884c\u5e38\u89c4\u8179\u8154\u6dcb\u5df4\u7ed3\u6e05\u626b\uff08\u98df\u7ba1\u764c\u5206\u7ec4\uff1aNo.16~No.20\uff09\uff08\u8bc1\u636e\u7ea7\u522b\uff1a\u9ad8\uff0c\u63a8\u8350\u5f3a\u5ea6\uff1a\u5f3a\u63a8\u8350\uff0c\u4e13\u5bb6\u7ec4\u8d5e\u540c\u7387\uff1a100%\uff09\u3002<\/p>\n<p>\u63a8\u8350\u610f\u89c122.Siewert\u2161\u3001\u2162\u578bAEG\uff1a\u5206\u671f\u4e3acT1N0\u8005\uff0c\u6309\u7167\u80c3\u764cD<sub>1<\/sub>\u548cD<sub>1<\/sub>+\u6dcb\u5df4\u7ed3\u6e05\u626b\u539f\u5219\u8fdb\u884c\uff1b\u8fdb\u5c55\u671fAEG\uff0c\u9700\u6309\u7167\u80c3\u764cD<sub>2<\/sub>\u6dcb\u5df4\u7ed3\u6e05\u626b\u539f\u5219\u8fdb\u884c\uff08\u8bc1\u636e\u7ea7\u522b\uff1a\u9ad8\uff0c\u63a8\u8350\u5f3a\u5ea6\uff1a\u5f3a\u63a8\u8350\uff0c\u4e13\u5bb6\u7ec4\u8d5e\u540c\u7387\uff1a97.87%\uff09\u3002<\/p>\n<p>\u5faa\u8bc1\u533b\u5b66\u8bc1\u636e\uff1aSiewert\u2160\u578bAEG\u7684\u6dcb\u5df4\u7ed3\u6e05\u626b\u5305\u62ec\u80f8\u8154\u6dcb\u5df4\u7ed3\u548c\u8179\u8154\u6dcb\u5df4\u7ed3\uff0c\u80f8\u8154\u6dcb\u5df4\u7ed3\u6e05\u626b\u6309\u7167\u98df\u7ba1\u764c\u7684\u5904\u7406\u539f\u5219\u8fdb\u884c\uff0c\u8179\u8154\u6dcb\u5df4\u7ed3\u6e05\u626b\u5305\u62ecNo.16~No.20\u3002\u5bf9\u4e8eSiewert\u2161\u3001\u2162\u578bAEG\uff0c\u6dcb\u5df4\u7ed3\u6e05\u626b\u4ee5\u8179\u8154\u4e3a\u4e3b\uff0c\u5e94\u884c\u7ecf\u8179\u8188\u808c\u88c2\u5b54\u5f84\u8def\u6216\u5355\u7eaf\u7ecf\u8179\u6839\u6cbb\u6027\u5168\u80c3\u5207\u9664+D<sub>2<\/sub>\u6dcb\u5df4\u7ed3\u6e05\u626b\uff1b\u4f46\u5bf9\u4e8e\u5176\u4e2d\u65e9\u671f\u75c5\u4f8b\uff08cT1N0\uff09\uff0c\u624b\u672f\u65f6\u53ef\u8003\u8651\u9009\u62e9\u6027\u884c\u6539\u826f\u624b\u672f\uff0c\u5373\u5168\u80c3\u5207\u9664+D<sub>1<\/sub>\/D<sub>1<\/sub>+\u6dcb\u5df4\u7ed3\u6e05\u626b\u6216\u8fd1\u7aef\u80c3\u5207\u9664+D<sub>1<\/sub>\/D<sub>1<\/sub>+\u6dcb\u5df4\u7ed3\u6e05\u626b\u3002\u4e2d\u56fd\u533b\u5e08\u534f\u4f1a\u5185\u955c\u533b\u5e08\u5206\u4f1a\u8179\u8154\u955c\u5916\u79d1\u533b\u5e08\u4e13\u4e1a\u59d4\u5458\u4f1a\u7b49\u5171\u540c\u53d1\u5e03\u300a\u4e2d\u56fd\u8179\u8154\u955c\u80c3\u764c\u6839\u6cbb\u624b\u672f\u8d28\u91cf\u63a7\u5236\u4e13\u5bb6\u5171\u8bc6\uff082022\u7248\uff09\u300b\u5bf9\u4e8e\u80c3\u764c\u6839\u6cbb\u672f\u4e2d\u6dcb\u5df4\u7ed3\u6e05\u626b\u7684\u5404\u7ec4\u6dcb\u5df4\u7ed3\u7684\u5b9a\u4e49\u548c\u89e3\u5256\u754c\u9650\u8fdb\u884c\u4e86\u89e3\u91ca\uff0c\u5e76\u5bf9\u6e05\u626b\u8981\u6c42\u63d0\u51fa\u4e86\u8d28\u91cf\u63a7\u5236\u6807\u51c6<sup>[20]<\/sup>\u3002\u4e00\u9879\u7eb3\u5165332\u4f8bcT2~4\u671f\u7684AEG\u524d\u77bb\u6027\u7814\u7a76\u7ed3\u679c\u663e\u793a\uff0c\u8179\u8154\u6dcb\u5df4\u7ed3\uff08No.1\u3001No.2\u3001No.3\u3001No.7\u3001No.9\u3001No.11p\uff09\u8f6c\u79fb\u7387\u5747&gt;10%<sup>[94]<\/sup>\u3002\u4e00\u9879\u65e5\u672c\u591a\u4e2d\u5fc3\u7814\u7a76\u5206\u6790\u4e86Siewert\u2161\u578bAEG\u75c5\u4f8b\u7684\u6dcb\u5df4\u7ed3\u8f6c\u79fb\u60c5\u51b5\uff0c\u4e0b\u7eb5\u9694\u6dcb\u5df4\u7ed3\u8f6c\u79fb\u7387\u4e3a17.7%\uff0c\u8179\u90e8\u6dcb\u5df4\u7ed3\u8f6c\u79fb\u4e3b\u8981\u4ee5No.1\u3001No.2\u3001No.3\u548cNo.7\u4e3a\u4e3b\uff0c\u5176\u8f6c\u79fb\u7387\u5206\u522b\u4e3a40.8%\u300131.7%\u300143.2%\u548c27.6%<sup>[96]<\/sup>\u3002\u53e6\u4e00\u9879\u7814\u7a76\u540c\u6837\u8868\u660e\uff0cSiewert\u2161\u578bAEG\u8179\u90e8\u6dcb\u5df4\u7ed3\u8f6c\u79fb\u7387\u9ad8\u4f4e\u6392\u5e8f\u4e3a\uff1a\u8d32\u95e8\u53f338.2%\u3001\u80c3\u5c0f\u5f2f\u4fa735.1%\u3001\u8d32\u95e8\u5de623.1%\u3001\u80c3\u5de6\u52a8\u810920.9%<sup>[97]<\/sup>\u3002\u4e00\u9879\u7eb3\u516521\u9879\u7814\u7a76\u5171\u8ba14 662\u4f8bSiewert\u2161\u3001\u2162\u578bAEG\u7684Meta\u5206\u6790\u7ed3\u679c\u663e\u793a\uff1aNo.1\u3001No.2\u3001No.3\u548cNo.7\u6dcb\u5df4\u7ed3\u8f6c\u79fb\u7387\u5747\u8d85\u8fc720%\uff0cNo.9\u3001No.19\u548cNo.110\u7684\u8f6c\u79fb\u7387\u572810%~20%\u4e4b\u95f4\uff0cNo.5\u3001No.6\u3001No.11d\u548cNo.12a\u7684\u8f6c\u79fb\u7387\u4f4e\u4e8e5%<sup>[42]<\/sup>\u3002<\/p>\n<p>\u80c3\u5468\u6dcb\u5df4\u7ed3\u5206\u7ec4\u548c\u6e05\u626b\u8303\u56f4\u4e3b\u8981\u53c2\u7167\u65e5\u672c\u80c3\u764c\u6cbb\u7597\u6307\u5357\u7b2c6\u7248\uff0c\u89c1\u88682<sup>[18]<\/sup>\u3002\u7ecf\u8179\u5168\u80c3\u5207\u9664D<sub>2<\/sub>\u6dcb\u5df4\u7ed3\u6e05\u626b\u8303\u56f4\u5305\u62ec\uff1aNo.1\u3001No.2\u3001No.3a\u3001No.3b\u3001No.4sa\u3001No.4sb\u3001No.4d\u3001No.5\u3001No.6\u3001No.7\u3001No.8a\u3001No.9\u3001No.11p\u3001No.11d\u548cNo.12a\uff1b\u82e5\u98df\u7ba1\u53d7\u7d2f\uff0c\u5219\u589e\u52a0No.19\u3001No.20\u548cNo.110\u3002\u89c1\u56fe3<sup>[18]<\/sup>\u3002cT1N0\u7684AEG\u8fd1\u7aef\u80c3\u5207\u9664D<sub>1<\/sub>+\u6dcb\u5df4\u7ed3\u6e05\u626b\u8303\u56f4\u5305\u62ec\uff1aNo.1\u3001No.2\u3001No.3a\u3001No.4sa\u3001No.4sb\u3001No.7\u3001No.8a\u3001No.9\u3001No.11p\u548cNo.11d\u7ec4\uff1b\u82e5\u98df\u7ba1\u53d7\u7d2f\uff0c\u5219\u589e\u52a0No.19\u3001No.20\u548cNo.110<sup>&nbsp;[18]<\/sup>\u3002<\/p>\n<\/p>\n<p>\uff08\u4e09\uff09AEG\u813e\u95e8\u6dcb\u5df4\u7ed3\u6e05\u626b\u89c4\u8303<\/p>\n<p>\u63a8\u8350\u610f\u89c123.\u7ecf\u8179\u624b\u672f\u813e\u95e8\u6dcb\u5df4\u7ed3\u6e05\u626b\uff08No.10\uff09\u4e0d\u4f5c\u4e3a\u5e38\u89c4\u63a8\u8350\uff1b\u5bf9\u4e8e\u6000\u7591\u5355\u7eaf\u813e\u95e8\u6dcb\u5df4\u7ed3\u8f6c\u79fb\u800c\u9884\u671f\u53efR<sub>0<\/sub>\u5207\u9664\u8005\uff0c\u53ef\u8003\u8651\u4fdd\u7559\u813e\u810f\u7684\u813e\u95e8\u6dcb\u5df4\u7ed3\u6e05\u626b\uff08\u8bc1\u636e\u7ea7\u522b\uff1a\u4e2d\uff0c\u63a8\u8350\u5f3a\u5ea6\uff1a\u5f3a\u63a8\u8350\uff0c\u4e13\u5bb6\u7ec4\u8d5e\u540c\u7387\uff1a100%\uff09\u3002<\/p>\n<p>\u63a8\u8350\u610f\u89c124.\u9884\u9632\u6027\u813e\u810f\u5207\u9664\u4e0d\u4f5c\u4e3a\u5e38\u89c4\u63a8\u8350\uff1b\u5bf9\u4e8eSiewert\u2161\u3001\u2162\u578bAEG\uff0c\u80bf\u7624\u4f4d\u4e8e\u80c3\u5927\u5f2f\u4fa7\u6216\u76f4\u63a5\u6d78\u6da6\u813e\u810f\uff08\u5305\u62ec\u80c3\u813e\u97e7\u5e26\uff09\u3001\u813e\u95e8\u6dcb\u5df4\u7ed3\u53ef\u7591\u8f6c\u79fb\u8005\uff0c\u5728\u9884\u671f\u53ef\u8fbeR<sub>0<\/sub>\u5207\u9664\u65f6\uff0c\u53ef\u8003\u8651\u8054\u5408\u813e\u810f\u5207\u9664\uff08\u8bc1\u636e\u7ea7\u522b\uff1a\u9ad8\uff0c\u63a8\u8350\u5f3a\u5ea6\uff1a\u5f3a\u63a8\u8350\uff0c\u4e13\u5bb6\u7ec4\u8d5e\u540c\u7387\uff1a100%\uff09\u3002<\/p>\n<p>\u5faa\u8bc1\u533b\u5b66\u8bc1\u636e\uff1a\u7b2c6\u7248\u65e5\u672c\u80c3\u764c\u6cbb\u7597\u6307\u5357\u4e2d\uff0c\u80c3\u4e2d\u4e0a\u90e8\u764c\u5efa\u8bae\u884c\u5168\u80c3\u5207\u9664+D<sub>2<\/sub>\u6dcb\u5df4\u7ed3\u6e05\u626b\uff0c\u5176\u4e2d\u5747\u672a\u5305\u62ec\u813e\u95e8\u6dcb\u5df4\u7ed3\uff08No.10\uff09\u7684\u6e05\u626b\uff0c\u5728EGJ\u4e0a\u4e0b2 cm\u7684AEG\u6dcb\u5df4\u7ed3\u6e05\u626b\u8303\u56f4\u4e2d\uff0c\u4ea6\u672a\u5305\u62ecNo.10<sup>[18]<\/sup>\u3002\u4e00\u9879\u5355\u4e2d\u5fc3\u56de\u987e\u6027\u75c5\u4f8b\u767b\u8bb0\u5206\u6790\u53d1\u73b0\uff0c\u80c3\u764c\u5168\u80c3\u5207\u9664\u75c5\u4f8b\u4e2dNo.10\u7684\u8f6c\u79fb\u7387\u4e3a16.4%\uff0c\u800cNo.10\u6dcb\u5df4\u7ed3\u6e05\u626b\u53ef\u4ee5\u4f7fSiewert\u2161\u3001\u2162\u578bAEG\u83b7\u5f97\u660e\u663e\u7684\u751f\u5b58\u83b7\u76ca<sup>[98]<\/sup>\u3002\u53e6\u4e00\u9879\u7814\u7a76\u53d1\u73b0\uff0cSiewert\u2162\u578bAEG\u7684No.10\u8f6c\u79fb\u7387\u9ad8\u8fbe21.9%\uff0c\u6e05\u626b\u83b7\u76ca\u6307\u6570\u4e3a9.4\uff0c\u813e\u95e8\u6dcb\u5df4\u7ed3\u6e05\u626b\u53ef\u5e26\u6765\u751f\u5b58\u83b7\u76ca<sup>[99]<\/sup>\u3002\u4e00\u9879\u65e5\u672c\u7684\u56de\u987e\u6027\u7814\u7a76\u4ea6\u80af\u5b9a\u4e86\u813e\u95e8\u6dcb\u5df4\u7ed3\u6e05\u626b\u5728Siewert\u2162\u578bAEG\u4e2d\u7684\u610f\u4e49\uff0c\u5c24\u5176\u5bf9\u4e8e\u975e\u5927\u5f2f\u4fa7\u80bf\u7624\uff0c\u5176\u8fdc\u671f\u751f\u5b58\u83b7\u76ca\u660e\u663e<sup>[100]<\/sup>\u3002\u56e0\u6b64\uff0c\u672c\u5171\u8bc6\u8ba4\u4e3a\uff0c\u5728\u5355\u7eaf\u53ef\u7591\u813e\u95e8\u6dcb\u5df4\u7ed3\u8f6c\u79fb\u800c\u813e\u810f\u672a\u76f4\u63a5\u6d78\u6da6\u8005\uff0c\u53ef\u9009\u62e9\u4fdd\u7559\u813e\u810f\u7684\u813e\u95e8\u6dcb\u5df4\u7ed3\u6e05\u626b\u3002\u76ee\u524d\u7814\u7a76\u8ba4\u4e3a\uff0c\u4fdd\u7559\u813e\u810f\u7684\u813e\u95e8\u6dcb\u5df4\u7ed3\u6e05\u626b\u5728\u6280\u672f\u4e0a\u662f\u5b89\u5168\u53ef\u884c\u7684\uff0c\u4e14\u53ef\u80fd\u5e26\u6765\u8fdc\u671f\u751f\u5b58\u83b7\u76ca\u3002<\/p>\n<p>JCOG\u20430110\u591a\u4e2d\u5fc3\u968f\u673a\u5bf9\u7167\u8bd5\u9a8c\uff0c\u7eb3\u5165cT2~4N0~2M0\u671f\u3001\u80c3\u5927\u5f2f\u672a\u53d7\u7d2f\u7684505\u4f8b\u80c3\u4e0a\u90e8\u764c\u60a3\u8005\uff0c\u8fdb\u884c\u5168\u80c3\u5207\u9664\u8054\u5408\u9884\u9632\u6027\u813e\u810f\u5207\u9664\u4e0e\u4fdd\u7559\u813e\u810f\u7684\u5206\u6790\u6bd4\u8f83\uff0c\u4e24\u7ec45\u5e74OS\u5dee\u5f02\u65e0\u7edf\u8ba1\u5b66\u610f\u4e49\uff08HR=0.88\uff0c95%CI\uff1a0.67~1.16\uff09\uff0c\u4f46\u813e\u5207\u9664\u7ec4\u5e76\u53d1\u75c7\u53d1\u751f\u7387\u66f4\u9ad8\u548c\u624b\u672f\u51fa\u8840\u91cf\u66f4\u591a<sup>[100]<\/sup>\u3002\u56e0\u6b64\uff0c\u5bf9\u4e8eSiewert\u2161\u3001\u2162\u578bAEG\u672a\u7d2f\u53ca\u80c3\u5927\u5f2f\u4fa7\u8005\uff0c\u4e0d\u5efa\u8bae\u9884\u9632\u6027\u813e\u5207\u9664\u3002\u57fa\u4e8e\u6b64\u7814\u7a76\uff0c\u65e5\u672c\u80c3\u764c\u6cbb\u7597\u6307\u5357\u5df2\u505a\u51fa\u4fee\u8ba2\uff0c\u4ec5\u5bf9\u4e8eT2~4\u671f\u7684\u80c3\u4e0a\u90e8\u764c\u76f4\u63a5\u4fb5\u72af\u813e\u810f\u3001\u6216\u4f4d\u4e8e\u80c3\u5927\u5f2f\u4fa7\u8005\uff0c\u53ef\u8003\u8651\u8054\u5408\u813e\u5207\u9664<sup>[17]<\/sup>\u3002\u53e6\u4e00\u9879Meta\u5206\u6790\u7eb3\u51654\u9879\u7814\u7a76\u5171\u8ba1978\u4f8b\u80c3\u4e0a\u90e8\u764c\uff0c\u53d1\u73b0\u8054\u5408\u813e\u810f\u5207\u9664\u5e76\u65e0\u751f\u5b58\u83b7\u76ca\uff0c\u4f46\u672f\u540e\u5e76\u53d1\u75c7\u98ce\u9669\u660e\u663e\u589e\u52a0\uff08OR=2.11\uff0cP&lt;0.001\uff09<sup>[101]<\/sup>\u3002\u56e0\u6b64\uff0c\u5f53\u524d\u8bc1\u636e\u4e0d\u5efa\u8baeAEG\u5e38\u89c4\u5b9e\u65bd\u8054\u5408\u813e\u810f\u5207\u9664\u3002<\/p>\n<p>\u4e03AEG\u5207\u9664\u672f\u540e\u6d88\u5316\u9053\u91cd\u5efa<\/p>\n<p>\u63a8\u8350\u610f\u89c125.AEG\u884c\u8fd1\u7aef\u80c3\u5207\u9664\u672f\u540e\u6d88\u5316\u9053\u91cd\u5efa\u65b9\u5f0f\u63a8\u8350\u987a\u5e8f\uff1a\u98df\u7ba1\u7ba1\u72b6\u80c3\u543b\u5408&gt;\u53cc\u901a\u9053\u543b\u5408&gt;SOFY\uff08Side\u2043Overlap\uff09\u543b\u5408&gt;\u53cc\u808c\u74e3\u6210\u5f62\u672f\uff08Kamikawa\u543b\u5408\uff09&gt;\u7a7a\u80a0\u95f4\u7f6e\u543b\u5408\uff08\u8bc1\u636e\u7ea7\u522b\uff1a\u4f4e\uff0c\u63a8\u8350\u5f3a\u5ea6\uff1a\u5f3a\u63a8\u8350\uff09\u3002<\/p>\n<p>\u63a8\u8350\u610f\u89c126.AEG\u884c\u5168\u80c3\u5207\u9664\u672f\u540e\u5efa\u8bae\u884c\u98df\u7ba1\u7a7a\u80a0Roux\u2043en\u2043Y\u543b\u5408\uff08\u8bc1\u636e\u7ea7\u522b\uff1a\u4f4e\uff0c\u63a8\u8350\u5f3a\u5ea6\uff1a\u5f3a\u63a8\u8350\uff0c\u4e13\u5bb6\u7ec4\u8d5e\u540c\u7387\uff1a97.87%\uff09\u3002<\/p>\n<p>\u5faa\u8bc1\u533b\u5b66\u8bc1\u636e\uff1aAEG\u884c\u8fd1\u7aef\u80c3\u5207\u9664\u540e\u6d88\u5316\u9053\u91cd\u5efa\u7684\u65b9\u5f0f\u9009\u62e9\u5c1a\u7f3a\u4e4f\u516c\u8ba4\u7684\u7406\u60f3\u65b9\u6cd5\u3002\u76ee\u524d\u8f83\u4e3a\u5e38\u89c1\u7684\u91cd\u5efa\u65b9\u5f0f\u5982\u4e0b\u3002<\/p>\n<p>1.\u98df\u7ba1\u7ba1\u72b6\u80c3\u543b\u5408\uff1a\u8be5\u543b\u5408\u65b9\u5f0f\u8f83\u5355\u7eaf\u98df\u7ba1\u6b8b\u80c3\u543b\u5408\u5728\u6297\u53cd\u6d41\u65b9\u9762\u6709\u4e00\u5b9a\u7684\u4f18\u52bf\uff0c\u5176\u539f\u7406\u5728\u4e8e\u5207\u9664\u5927\u90e8\u5206\u80c3\u58c1\u51cf\u5c11\u80c3\u9178\u5206\u6ccc\uff0c\u7ba1\u72b6\u80c3\u957f\u5ea6\u4f7f\u80c3\u5185\u5bb9\u4e0d\u6613\u53cd\u6d41\uff0c\u6b8b\u80c3\u4f53\u79ef\u5c0f\u5229\u4e8e\u6392\u7a7a\u3002\u7ba1\u72b6\u80c3\u543b\u5408\u53ef\u4ee5\u5728\u4fdd\u8bc1\u98df\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c\u5bf9\u4e8e\u8fdb\u5c55\u671fAEG\uff0c\u65b0\u8f85\u52a9\u5316\u7597\u540e\u8fdb\u884c\u624b\u672f\u7684\u4e34\u5e8a\u6548\u679c\u663e\u8457\u4f18\u4e8e\u5355\u7eaf\u624b\u672f<sup>[110\u2043114]<\/sup>\u3002\u56e0\u6b64\uff0c\u5bf9\u4e8e\u53ef\u5207\u9664\u7684\u8fdb\u5c55\u671fAEG\u53ef\u884c\u65b0\u8f85\u52a9\u5316\u7597\u3002\u4e00\u9879\u5305\u542b14\u9879\u968f\u673a\u5bf9\u7167\u8bd5\u9a8c\u5171\u8ba1\u7eb3\u51651 247\u4f8b\u60a3\u8005\u7684Meta\u5206\u6790\u7ed3\u679c\u663e\u793a\uff0c\u57fa\u4e8eFLOT\u65b9\u6848\u7684\u672f\u524d\u65b0\u8f85\u52a9\u5316\u7597\u76f8\u8f83\u4e8e\u5355\u72ec\u624b\u672f\uff0c\u53ef\u4ee5\u7ed9AEG\u60a3\u8005\u5e26\u6765\u660e\u663e\u7684\u751f\u5b58\u83b7\u76ca\uff0c\u5176OS\u548c\u65e0\u7624\u751f\u5b58\u7387\u663e\u8457\u63d0\u5347<sup>[115]<\/sup>\u3002\u57fa\u4e8e\u4e0a\u8ff0\u9ad8\u8d28\u91cf\u4e34\u5e8a\u7814\u7a76\u7ed3\u679c\u548c\u6307\u5357\u7684\u63a8\u8350\uff0c\u672c\u5171\u8bc6\u5efa\u8bae\uff0c\u5bf9\u4e8e\u53ef\u884cR<sub>0<\/sub>\u5207\u9664\u7684AEG\u75c5\u4f8b\uff0c\u5f3a\u70c8\u63a8\u8350\u884c\u672f\u524d\u65b0\u8f85\u52a9\u5316\u7597\u3002<\/p>\n<p>\u98df\u7ba1\u764c\u548cAEG\u7684NCCN\u8bca\u6cbb\u6307\u5357\u4e2d\u63d0\u51fa\uff0c\u5bf9\u4e8e\u80bf\u7624\u6d78\u6da6\u5927\u8840\u7ba1\u3001\u5fc3\u810f\u548c\u6c14\u7ba1\u800c\u4e0d\u9002\u5b9c\u5916\u79d1\u624b\u672f\u6cbb\u7597\u7684cT4b\u75c5\u4f8b\uff0c\u63a8\u8350\u8fdb\u884c\u65b0\u8f85\u52a9\u653e\u5316\u7597\u52a0\u514d\u75ab\u6cbb\u7597<sup>[15]<\/sup>\u3002\u4f46\u5728\u80c3\u764cNCCN\u6307\u5357\u548c\u65e5\u672c\u80c3\u764c\u8bca\u7597\u89c4\u8303\u4e2d\u5efa\u8bae\uff0c\u82e5cT4b\u75c5\u4f8b\u9884\u671f\u53ef\u8fbeR<sub>0<\/sub>\u5207\u9664\uff0c\u5219\u53ef\u8003\u8651\u6269\u5927\u8054\u5408\u810f\u5668\u5207\u9664<sup>[16\u204318]<\/sup>\u3002\u9488\u5bf9AEG\u7684cT4b\u75c5\u4f8b\uff0c\u5728\u6d78\u6da6\u8188\u808c\u3001\u5de6\u4fa7\u80be\u4e0a\u817a\u3001\u5de6\u809d\u548c\u813e\u810f\u65f6\uff0c\u7ecf\u76f8\u5173\u5f71\u50cf\u5b66\u68c0\u67e5\u548c\u8179\u8154\u955c\u63a2\u67e5\u6392\u9664\u5176\u4ed6\u8fdc\u5904\u8f6c\u79fb\u56e0\u7d20\u8005\uff0c\u63a5\u53d7\u65b0\u8f85\u52a9\u6cbb\u7597\u540e\uff0c\u53ef\u8c28\u614e\u5730\u8fdb\u884c\u624b\u672f\u5207\u9664\u6307\u5f81\u7684\u8bc4\u4f30\uff0c\u800c\u57fa\u4e8e\u7cbe\u51c6\u5206\u671f\u548c\u7cbe\u51c6\u8bc4\u4f30\u7684\u591a\u5b66\u79d1\u65b0\u8f85\u52a9\u6cbb\u7597\u6a21\u5f0f\uff0c\u662f\u8be5\u7c7b\u75c5\u4f8b\u7684\u4e34\u5e8a\u6700\u4f73\u9009\u62e9\u3002<\/p>\n<p>\u63a8\u8350\u610f\u89c128. \u5728\u5c40\u90e8\u8fdb\u5c55\u671fSiewert\u2160\u578bAEG\u75c5\u4f8b\u4e2d\uff0c\u5efa\u8bae\u5f00\u5c55\u65b0\u8f85\u52a9\u653e\u5316\u7597\uff1bSiewert\u2161\u578b\u75c5\u4f8b\u5efa\u8bae\u9009\u62e9\u6027\u5f00\u5c55\u65b0\u8f85\u52a9\u653e\u5316\u7597\uff0c\u5b9c\u5728\u63a2\u7d22\u6027\u4e34\u5e8a\u7814\u7a76\u4e2d\u5e94\u7528\uff1b\u5728Siewert\u2162\u578b\u75c5\u4f8b\u4e2d\uff0c\u6682\u4e0d\u63a8\u8350\u8fdb\u884c\u65b0\u8f85\u52a9\u653e\u5316\u7597\uff08\u8bc1\u636e\u7ea7\u522b\uff1a\u4e2d\uff0c\u63a8\u8350\u5f3a\u5ea6\uff1a\u5f3a\u63a8\u8350\uff0c\u4e13\u5bb6\u7ec4\u8d5e\u540c\u7387\uff1a91.49%\uff09\u3002<\/p>\n<p>\u5faa\u8bc1\u533b\u5b66\u8bc1\u636e\uff1a\u5728\u6211\u56fd\uff0c\u5355\u7eaf\u653e\u7597\u5728AEG\u56f4\u624b\u672f\u671f\u5e94\u7528\u4ecd\u4e0d\u666e\u904d\uff0c\u4e00\u822c\u5728\u5316\u7597\u57fa\u7840\u4e0a\u8054\u5408\u5e94\u7528\u3002\u968f\u7740\u653e\u7597\u6280\u672f\u7684\u8fdb\u6b65\uff0c\u56fd\u9645\u4e0a\u5173\u4e8eAEG\u65b0\u8f85\u52a9\u653e\u5316\u7597\u7684\u4e34\u5e8a\u7814\u7a76\u9010\u6e10\u589e\u591a<sup>[116\u2043117]<\/sup>\u3002\u5728\u98df\u7ba1\u764cNCCN\u6307\u5357\u4e2d\uff0c\u5bf9cT1b~4aN0~N+M0\u3001\u9884\u671f\u884c\u98df\u7ba1\u5207\u9664\u672f\u7684Siewert\u2160\u578bAEG\u75c5\u4f8b\uff0c\u4f18\u9009\u65b0\u8f85\u52a9\u653e\u5316\u7597<sup>[15]<\/sup>\u3002\u4f46\u5728\u80c3\u764cNCCN\u6307\u5357\u548c\u65e5\u672c\u80c3\u764c\u6cbb\u7597\u6307\u5357\u4e2d\uff0c\u5173\u4e8e\u56f4\u624b\u672f\u671f\u653e\u5316\u7597\u7684\u63a8\u8350\u5f3a\u5ea6\u8f83\u4f4e<sup>[17\u204318,38]<\/sup>\u3002CROSS\u8bd5\u9a8c\uff08368\u4f8b\u98df\u7ba1\u764c\u548cAEG\uff0ccT1N1\u6216cT2~3N0~1\uff09\u53d1\u73b0\uff0cAEG\uff08\u536027%\uff09\u63a5\u53d7\u65b0\u8f85\u52a9\u653e\u5316\u7597\u8f83\u5355\u7eaf\u624b\u672f\u5207\u9664\u5177\u6709\u66f4\u9ad8\u7684R<sub>0<\/sub>\u5207\u9664\u7387\uff0c\u4e1410\u5e74\u671f\u968f\u8bbf\u7ed3\u679c\u663e\u793a\uff0c\u5176\u8fdc\u671f\u751f\u5b58\u83b7\u76ca\u660e\u663e<sup>[116]<\/sup>\u3002\u4e00\u9879\u6bd4\u8f83Siewert\u2160\u3001\u2161\u3001\u2162\u578bAEG\uff08cT3~4NxM0\uff09\u63a5\u53d7\u65b0\u8f85\u52a9\u653e\u5316\u7597\u4e0e\u5355\u7eaf\u65b0\u8f85\u52a9\u5316\u7597\u751f\u5b58\u7ed3\u5c40\u7684POET\u8bd5\u9a8c\uff0c\u56e0\u62db\u52df\u8fdb\u5ea6\u7f13\u6162\uff0c\u5728\u5165\u7ec427.9%\u8ba1\u5212\u75c5\u4f8b\u540e\u4e2d\u6b62\uff0c3\u5e74OS\u5206\u522b\u4e3a47.4%\u548c27.7%\uff08P=0.07\uff09\uff0c3\u5e74\u65e0\u8fdb\u5c55\u751f\u5b58\u7387\uff08progression\u2043free survival\uff0cPFS\uff09\u5206\u522b\u4e3a76.5%\u548c59.0%\uff08P=0.06\uff09<sup>[114]<\/sup>\u3002\u53e6\u4e00\u7eb3\u516513 783\u4f8b\u7684\u56de\u987e\u6027\u7814\u7a76\u7ed3\u679c\u663e\u793a\uff0c\u65b0\u8f85\u52a9\u653e\u5316\u7597\u76f8\u8f83\u4e8e\u5355\u7eaf\u65b0\u8f85\u52a9\u5316\u7597\uff0c\u53ef\u663e\u8457\u63d0\u5347AEG\u80bf\u7624\u7684\u5b8c\u5168\u7f13\u89e3\u7387<sup>[117]<\/sup>\u3002\u5c3d\u7ba1POET\u7814\u7a76\u672a\u5b8c\u6210\u62db\u52df\u8ba1\u5212\uff0c\u4f46\u65b0\u8f85\u52a9\u653e\u5316\u7597\u7684\u751f\u5b58\u4f18\u52bf\u5df2\u5f00\u59cb\u4f53\u73b0\u3002\u5176\u4ed6\u6bd4\u8f83\u65b0\u8f85\u52a9\u653e\u5316\u7597\u548c\u65b0\u8f85\u52a9\u5316\u7597\u7684\u4e34\u5e8a\u8bd5\u9a8cICORG 10\u204314\u548cTOPGEAR\u7ed3\u679c\u5373\u5c06\u516c\u5e03\u3002<\/p>\n<p>\u63a8\u8350\u610f\u89c129.\u5305\u542bPD\u20431\/PD\u2043L1\u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\u7684\u65b9\u6848\u7528\u4e8eAEG\u7684\u672f\u524d\u65b0\u8f85\u52a9\u6cbb\u7597\uff0c\u76ee\u524d\u8fd8\u7f3a\u4e4f\u9ad8\u7ea7\u522b\u7684\u5faa\u8bc1\u533b\u5b66\u8bc1\u636e\u3002\u56e0\u6b64\uff0c\u5efa\u8bae\u5728\u4e34\u5e8a\u7814\u7a76\u7684\u6846\u67b6\u5185\u5f00\u5c55\uff08\u8bc1\u636e\u7ea7\u522b\uff1a\u4e2d\uff0c\u63a8\u8350\u5f3a\u5ea6\uff1a\u5f31\u63a8\u8350\uff0c\u4e13\u5bb6\u7ec4\u8d5e\u540c\u7387\uff1a97.87%\uff09\u3002<\/p>\n<p>\u5faa\u8bc1\u533b\u5b66\u8bc1\u636e\uff1a\u8fd1\u5e74\u6765\uff0cPD\u20431\/PD\u2043L1\u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\u7b49\u514d\u75ab\u6cbb\u7597\u624b\u6bb5\u5728\u6539\u5584\u5305\u62ecAEG\u5728\u5185\u7684\u665a\u671f\u4e0a\u6d88\u5316\u9053\u80bf\u7624\u60a3\u8005\u7684\u957f\u671f\u9884\u540e\u65b9\u9762\u53d6\u5f97\u663e\u8457\u6210\u6548<sup>[118\u2043120]<\/sup>\u3002\u665a\u671fAEG\u4e2d\u6240\u83b7\u5f97\u7684\u80bf\u7624\u5b66\u7597\u6548\u4f18\u52bf\u4e5f\u5f15\u53d1\u4e86\u5bf9\u63a2\u7d22\u65b0\u8f85\u52a9\u514d\u75ab\u8054\u5408\u6cbb\u7597\u6a21\u5f0f\u7684\u7814\u7a76\u70ed\u60c5\u3002\u8bb8\u591a\u524d\u77bb\u6027\u2161\u671f\u4e34\u5e8a\u8bd5\u9a8c\u8bc1\u5b9e\uff0c\u672f\u524d\u65b0\u8f85\u52a9\u5316\u7597\u8054\u5408\u57fa\u4e8ePD\u20431\/PD\u2043L1\u514d\u75ab\u68c0\u67e5\u70b9\u7684\u514d\u75ab\u6cbb\u7597\u5728\u80c3\u764c\u3001\u98df\u7ba1\u764c\u548cAEG\u4e2d\u7684\u4f18\u52bf\uff0c\u5176\u5b89\u5168\u6027\u548c\u6539\u5584\u75c5\u7406\u7f13\u89e3\u7387\u65b9\u9762\u6709\u660e\u663e\u4f18\u52bf<sup>[121\u2043123]<\/sup>\u3002\u5c3d\u7ba1\u5982\u6b64\uff0c\u9274\u4e8e\u5c1a\u7f3a\u4e4f\u5927\u89c4\u6a21\u524d\u77bb\u6027\u3001\u968f\u673a\u5bf9\u7167\u3001\u2162\u671f\u4e34\u5e8a\u7814\u7a76\u52a0\u4ee5\u8fdb\u4e00\u6b65\u9a8c\u8bc1\uff0c\u56e0\u6b64\uff0c\u4ec5\u63a8\u8350\u5728\u4e34\u5e8a\u7814\u7a76\u8303\u7574\u5185\u5f00\u5c55\uff0c\u5e76\u4e14\u5145\u5206\u544a\u77e5\u6f5c\u5728\u98ce\u9669\u5e76\u987b\u83b7\u5f97\u60a3\u8005\u7684\u77e5\u60c5\u540c\u610f\u3002<\/p>\n<p>\u4e5dAEG\u5916\u79d1\u6cbb\u7597\u5f85\u63a2\u7d22\u7684\u76f8\u5173\u95ee\u9898<\/p>\n<p>\u76ee\u524d\uff0c\u5c1a\u5c5e\u4e8eAEG\u5916\u79d1\u6cbb\u7597\u5f85\u63a2\u7d22\u7684\u76f8\u5173\u95ee\u9898\u5305\u62ec\uff1a\uff081\uff09Siewert\u2161\u578bAEG\u7684\u6dcb\u5df4\u7ed3\u6e05\u626b\u8303\u56f4\uff1b\uff082\uff09Siewert\u2161\u578bAEG\u7684\u5207\u9664\u8303\u56f4\uff1b\uff083\uff09\u8179\u8154\u955c\u6cbb\u7597\u8fdb\u5c55\u671fSiewert\u2161\u3001\u2162\u578bAEG\u7684\u8fdc\u671f\u9884\u540e\uff1b\uff084\uff09\u7ecf\u8179\u8188\u808c\u88c2\u5b54\u5f84\u8def\u5207\u9664Siewert\u2161\u3001\u2162\u578bAEG\u7684\u5b89\u5168\u98df\u7ba1\u5207\u7f18\u8ddd\u79bb\uff1b\uff085\uff09\u8fd1\u7aef\u80c3\u5207\u9664\u540e\u7684\u6d88\u5316\u9053\u91cd\u5efa\u65b9\u5f0f\u3002<\/p>\n<p>\u7ed3\u8bed 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u79d1\u5927\u5b66\u9644\u5c5e\u7701\u7acb\u533b\u9662\uff09\u3001\u674e\u5411\u6960\uff08\u90d1\u5dde\u5927\u5b66\u7b2c\u4e00\u9644\u5c5e\u533b\u9662\uff09\u3001\u674e\u5fd7\u521a\uff08\u4e0a\u6d77\u5e02\u80f8\u79d1\u533b\u9662\uff09\u3001\u674e\u5b50\u79b9\uff08\u5317\u4eac\u5927\u5b66\u80bf\u7624\u533b\u9662\uff09\u3001\u6881\u5bd2\uff08\u5929\u6d25\u533b\u79d1\u5927\u5b66\u9644\u5c5e\u80bf\u7624\u533b\u9662\uff09\u3001\u6881\u54c1\uff08\u5927\u8fde\u533b\u79d1\u5927\u5b66\u9644\u5c5e\u7b2c\u4e00\u533b\u9662\uff09\u3001\u5ed6\u6c38\u5fb7\uff08\u534e\u4e2d\u79d1\u6280\u5927\u5b66\u540c\u6d4e\u533b\u5b66\u9662\u9644\u5c5e\u534f\u548c\u533b\u9662\uff09\u3001\u5218\u51e4\u6797\uff08\u590d\u65e6\u5927\u5b66\u9644\u5c5e\u80bf\u7624\u533b\u9662\uff09\u3001\u5218\u4fca\u5cf0\uff08\u6cb3\u5317\u533b\u79d1\u5927\u5b66\u7b2c\u56db\u533b\u9662\uff09\u3001\u67f3\u7855\u5ca9\uff08\u798f\u5efa\u7701\u80bf\u7624\u533b\u9662\uff09\u3001\u6bdb\u53cb\u751f\uff08\u4e2d\u56fd\u533b\u5b66\u79d1\u5b66\u9662\u80bf\u7624\u533b\u9662\uff09\u3001\u5b59\u76ca\u7ea2\uff08\u590d\u65e6\u5927\u5b66\u9644\u5c5e\u4e2d\u5c71\u533b\u9662\uff09\u3001\u6240\u5251\uff08\u5409\u6797\u5927\u5b66\u7b2c\u4e00\u533b\u9662\uff09\u3001\u8c2d\u9ece\u6770\uff08\u590d\u65e6\u5927\u5b66\u9644\u5c5e\u4e2d\u5c71\u533b\u9662\uff09\u3001\u9676\u51ef\u96c4\uff08\u534e\u4e2d\u79d1\u6280\u5927\u5b66\u540c\u6d4e\u533b\u5b66\u9662\u9644\u5c5e\u534f\u548c\u533b\u9662\uff09\u3001\u738b\u632f\u5b81\uff08\u4e2d\u56fd\u533b\u79d1\u5927\u5b66\u9644\u5c5e\u7b2c\u4e00\u533b\u9662\uff09\u3001\u738b\u5141\uff08\u56db\u5ddd\u5927\u5b66\u534e\u897f\u533b\u9662\uff09\u3001\u5f90\u6cfd\u5bbd\uff08\u6c5f\u82cf\u7701\u4eba\u6c11\u533b\u9662\uff09\u3001\u859b\u82f1\u5a01\uff08\u54c8\u5c14\u6ee8\u533b\u79d1\u5927\u5b66\u9644\u5c5e\u80bf\u7624\u533b\u9662\uff09\u3001\u6768\u6606\uff08\u56db\u5ddd\u5927\u5b66\u534e\u897f\u533b\u9662\uff09\u3001\u4e8e\u632f\u6d9b\uff08\u4e2d\u56fd\u533b\u5b66\u79d1\u5b66\u9662\u80bf\u7624\u533b\u9662\u6df1\u5733\u533b\u9662\uff09\u3001\u4f59\u4f69\u6b66\uff08\u9646\u519b\u519b\u533b\u5927\u5b66\u9644\u5c5e\u897f\u5357\u533b\u9662\uff09\u3001\u8881\u52c7\uff08\u56db\u5ddd\u5927\u5b66\u534e\u897f\u533b\u9662\uff09\u3001\u81e7\u6f5e\uff08\u4e0a\u6d77\u4ea4\u901a\u5927\u5b66\u533b\u5b66\u9662\u9644\u5c5e\u745e\u91d1\u533b\u9662\uff09\u3001\u5f20\u4ec1\u6cc9\uff08\u5b89\u5fbd\u533b\u79d1\u5927\u5b66\u7b2c\u4e00\u9644\u5c5e\u533b\u9662\uff09\u3001\u5f20\u7ef4\u6c49\uff08\u56db\u5ddd\u5927\u5b66\u534e\u897f\u533b\u9662\uff09<\/p>\n<p>\u6267\u7b14\uff1a\u56db\u5ddd\u5927\u5b66\u534e\u897f\u533b\u9662\u56e2\u961f\uff08\u5218\u51ef\u3001\u6768\u7389\u8d4f\u3001\u6768\u6606\u3001\u8881\u52c7\u3001\u9648\u9f99\u5947\u3001\u80e1\u5efa\u6606\uff09<\/p>\n<p>\u5229\u76ca\u51b2\u7a81 &nbsp;\u6240\u6709\u4f5c\u8005\u5747\u58f0\u660e\u4e0d\u5b58\u5728\u5229\u76ca\u51b2\u7a81<\/p>\n<p>\u6ed1\u52a8\u9605\u8bfb\u53c2\u8003\u6587\u732e<\/p>\n<p>[1] Sung H, Ferlay J, Siegel RL, et al. 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