{"id":27846,"date":"2024-03-27T04:01:22","date_gmt":"2024-03-27T04:01:22","guid":{"rendered":"https:\/\/zydq.1006ss.com\/?p=27846"},"modified":"2024-03-27T04:01:22","modified_gmt":"2024-03-27T04:01:22","slug":"%e4%b9%b3%e8%85%ba%e5%b8%b8%e7%94%a8%e5%85%8d%e7%96%ab%e7%bb%84%e5%8c%96","status":"publish","type":"post","link":"http:\/\/zydq.1006ss.com\/?p=27846","title":{"rendered":"\u4e73\u817a\u5e38\u7528\u514d\u75ab\u7ec4\u5316"},"content":{"rendered":"<ul>\n<li>\n<p>\u4e09\u89d2\u5f62\u9ad8\u5ea6\u4ee3\u8868\u8868\u8fbe\u7684\u5f3a\u5ea6\u3002<\/p>\n<\/li>\n<li>\n<p>CK5\u3001CK5\/6\u3001CK14\u9ad8\u5206\u5b50\u91cf\u89d2\u86cb\u767d\uff0c\u5e72\u7ec6\u80de\u8868\u8fbe\u3002<\/p>\n<\/li>\n<li>\n<p>\u4eba\u4f53\u5176\u4ed6\u4e0a\u76ae\/\u95f4\u8d28\u7ec6\u80deER\/PR\/AR\u4e5f\u53ef \uff1a\u5b50\u5bab\u3001\u6c57\u817a\u3001\u6d8e\u817a\u3001\u524d\u5217\u817a\u7b49\u3002<\/p>\n<\/li>\n<li>\n<p>\u4e73\u817a\u764c\u6a21\u62df\u6b63\u5e38\u4e73\u817a\u4e0a\u76ae\u7684\u67d0\u4e2a\u5206\u5316\u9636\u6bb5\uff0c\u8868\u73b0\u4e3a\u4e0d\u540c\u7684\u5206\u5b50\u5206\u578b\/\u514d\u75ab\u8868\u578b\uff1aTNC\uff08\u4e09\u9634\u6027\uff09\uff1bHER2\u9633\u6027\u578b\uff1bLuminal B\u578b\uff1bLuminal A\u578b\u3002\u6709\u7684\u662f\u6a21\u62df\u7ec8\u672b\u817a\u4e0a\u76ae\u5206\u5316\uff0cER\u7ecf\u5e38\u5f3a\u9633\u6027\uff0c\u5373Luminal\u578b\uff1b\u6709\u7684\u6a21\u62df\u539f\u59cb\u7684\u5e72\u7ec6\u80de\u7684\u5206\u5316\uff0c\u6210\u719f\u6807\u8bb0\u4e00\u4e2a\u4e0d\u9633\uff0cER\u3001PR\u3001HER2\u4e09\u9634\u6027\u3002<\/p>\n<\/li>\n<\/ul>\n<p>\u808c\u4e0a\u76ae\u6807\u8bb0\u7269\u7684\u5e94\u7528<\/p>\n<p>\u4e00\u3001\u5e38\u7528\u6807\u8bb0\u7269\u4ecb\u7ecd<\/p>\n<p>\u808c\u4e0a\u76ae\u6807\u8bb0\u7269<\/p>\n<p>S100\u65e9\u671f\u662f\u808c\u4e0a\u76ae\u6807\u8bb0\u7269\uff0c\u5b58\u5728\u4ea4\u53c9\u53cd\u5e94\uff0c\u5df2\u57fa\u672c\u88ab\u653e\u5f03\u4f7f\u7528\u3002\u4ec5\u5728\u5c11\u6570\u60c5\u51b5\u4e0b\u4f7f\u7528\uff08\u5982\uff1a\u786e\u5b9a\u662f\u5426\u4e3a\u817a\u808c\u4e0a\u76ae\u75c5\u53d8\uff0c\u6216\u9274\u522b\u808c\u4e0a\u76ae\u75c5\u53d8\u548c\u9cde\u72b6\u4e0a\u76ae\u75c5\u53d8\uff0c\u4f7f\u7528P63\uff0cCK5\/6\u6709\u4ea4\u53c9\u65f6\uff09\u3002<\/p>\n<p>1<\/p>\n<p>2<\/p>\n<p>\u56fe1 \u63a8\u8350\u80de\u6838 \u80de\u6d46\u7684\u7ec4\u5408\u3002<\/p>\n<p>MSA\/SMA\u4e0e\u808c\u7ea4\u7ef4\u6bcd\u7ec6\u80de\u4ea4\u53c9\u53cd\u5e94\u6bd4\u8f83\u91cd\uff0c\u4f46\u662f\u4e0e\u808c\u4e0a\u76ae\u7ec6\u80de\u5b9a\u4f4d\u4e0d\u540c\u3002<\/p>\n<p>\u56fe2 calponin\u6bd4\u8f83\u654f\u611f\uff0c\u7f3a\u70b9\u662f\u4e0e\u808c\u7ea4\u7ef4\u6bcd\u7ec6\u80de\u6709\u4ea4\u53c9\u3002\u4e0a\u9762\u4e24\u4e2a\u56fe\u663e\u793a\u808c\u4e0a\u76ae\uff0c\u5f80\u817a\u8154\u817a\u4e0a\u76ae\u65b9\u5411\u6709\u51f8\u8d77\u3002\u4e0b\u9762\u4e24\u56fe\u663e\u793a\u808c\u7ea4\u7ef4\u6bcd\u7ec6\u80de\uff0c\u65e0\u51f8\u8d77\u3002<\/p>\n<p>1<\/p>\n<p>2<\/p>\n<p>\u56fe1 P63\u80de\u6838\u67d3\u8272\uff0c\u5c24\u5176\u662f\u7528\u5728\u4e73\u5934\u72b6\u75c5\u53d8\uff0c\u9274\u522b\u7ea4\u7ef4\u8840\u7ba1\u8f74\u5fc3\u8fd8\u662f\u808c\u4e0a\u76ae\u3002\u7f3a\u70b9\u662f\u67d3\u8272\u4e0d\u8fde\u7eed\u3002<\/p>\n<p>\u56fe2 CK5\/6\u53ef\u4ee5\u4f5c\u4e3a\u808c\u4e0a\u76ae\u6807\u8bb0\u7269\u505a\u53c2\u8003\uff0c\u6ce8\u610f\u6b63\u5e38\u5c0f\u53f6\u7684\u7ec8\u672b\u5bfc\u7ba1\u6216\u817a\u6ce1\u808c\u4e0a\u76aeCK5\/6\u9634\u6027\u3002\u53ef\u4ee5\u663e\u793a\u6591\u9a73\u4e0d\u4e00\u7684\u8154\u9762\u7684\u7740\u8272\u3002<\/p>\n<p>1<\/p>\n<p>2<\/p>\n<p>\u56fe1 \u5728HE\u4e2d\u975e\u5e38\u5feb\u6377\u6709\u6548\u7684\u8bc6\u522b\u5bfc\u7ba1\u539f\u4f4d\u764c\u6709\u65e0\u5fae\u6d78\u6da6\u7684\u65b9\u5f0f\u662f\uff1a\u5728\u5bcc\u4e8e\u6dcb\u5df4\u7ec6\u80de\u7684\u533a\u57df\u5185\u770b\u6709\u65e0\u5fae\u5c0f\u6d78\u6da6\u3002<\/p>\n<p>\u56fe2 \u5982\u679c\u662f\u5355\u4e2a\u7ec6\u80de\u6216\u8005\u4e24\u4e09\u4e2a\u7ec6\u80de\u57cb\u5728\u6dcb\u5df4\u7ec6\u80de\u5806\u91cc\u9762\uff0c\u800c\u808c\u4e0a\u76ae\u67d3\u8272\u9634\u6027\uff0c\u975e\u5e38\u5bb9\u6613\u9057\u6f0f\u5fae\u6d78\u6da6\u3002\u5373\u4f7f\u770b\u5230\u4e86\u53ef\u80fd\u4e5f\u65e0\u6cd5\u786e\u8ba4\u662f\u8840\u7ba1\u5185\u76ae\uff0c\u7ec4\u7ec7\u7ec6\u80de\u8fd8\u662f\u80bf\u7624\u7ec6\u80de\uff0c\u56e0\u6b64\u63a8\u8350\u53cc\u6807\u8bb0\u67d3\u8272\uff0c\u7ea2\u8272\u4ee3\u8868\u4e0a\u76ae\uff0c\u68d5\u8272\u4ee3\u8868\u808c\u4e0a\u76ae\u3002<\/p>\n<p>\u6709\u4e9b\u975e\u5e38\u9760\u8fd1\u80bf\u7624\u4e3b\u4f53\u7684\u65f6\u5019\uff0c\u53ef\u80fd\u5207\u9762\u5bfc\u81f4\u6ca1\u6709\u5207\u5230P63\u9633\u6027\u7684\u808c\u4e0a\u76ae\uff0c\u56e0\u6b64\u5efa\u8bae\u65e2\u6709AE1\/3 P63\uff0c\u53c8\u6709AE1\/3 calponin\u7684\u53cc\u6807\u8bb0\u67d3\u8272\u3002<\/p>\n<p>\u4e8c\u3001\u6709\u4e9b\u826f\u6027\u75c5\u53d8\u808c\u4e0a\u76ae\u53ef\u4ee5\u4e0d\u660e\u663e<\/p>\n<p>1<\/p>\n<p>2<\/p>\n<p>\u56fe1 \u5fae\u817a\u4f53\u817a\u75c5<\/p>\n<p>\u56fe2 \u6d78\u6da6\u6027\u4e0a\u76ae\u75c5\uff0c\u666e\u901a\u578b\u589e\u751f\u7684\u8868\u578b\uff0cCK5\/6\u6591\u9a73\u4e0d\u4e00\u7684\u9633\u6027\uff0cER\u90e8\u5206\u9633\u6027\uff0c\u4f46\u662f\u67d0\u4e9b\u533a\u57df\u808c\u4e0a\u76ae\u6d88\u5931\uff0c\u6709\u65f6\u5019\u8303\u56f4\u8fd8\u5f88\u5e7f\u6cdb\uff0c\u672c\u8d28\u8fd8\u662f\u786c\u5316\u6027\u4e73\u817a\u75c5\uff0c\u662f\u4e00\u79cd\u826f\u6027\u75c5\u53d8\uff0c\u6709\u7684\u6587\u732e\u8ba4\u4e3a\u662f\u6076\u6027\u6f5c\u80fd\u4e0d\u786e\u5b9a\u7684\u75c5\u53d8\u3002<\/p>\n<p>1<\/p>\n<p>2<\/p>\n<p>\u56fe2 \u5de6P63\uff0c\u53f3calponin\u3002P63\u5728\u786c\u5316\u6027\u75c5\u53d8\u4e2d\u6709\u6570\u91cf\u7684\u51cf\u5c11\uff0c\u5076\u5c14\u4e00\u4e2a\u5207\u9762\u53ef\u80fd\u6b63\u597d\u6ca1\u5207\u5230P63\u67d3\u8272\u7684\u808c\u4e0a\u76ae\u7ec6\u80de\u3002<\/p>\n<p>1<\/p>\n<p>2<\/p>\n<p>\u56fe1 \u786c\u5316\u6027\u75c5\u53d8\u4e2d\u7279\u522b\u63a8\u8350\u4f7f\u7528\u80de\u6d46\u67d3\u8272\u7684\u5b8c\u6574\u7684\u808c\u4e0a\u76ae\u7740\u8272\u3002<\/p>\n<p>\u56fe2 \u826f\u6027\u5927\u6c57\u817a\u75c5\u53d8\uff0c\u808c\u4e0a\u76ae\u53ef\u4ee5\u51cf\u5c11\u6216\u6d88\u5931\u3002<\/p>\n<p>1<\/p>\n<p>2<\/p>\n<p>\u7a7f\u523a\u5bfc\u81f4\u4e0a\u76ae\u79fb\u4f4d\uff0c\u808c\u4e0a\u76ae\u9634\u6027\uff0c\u6709\u6548\u7684\u65b9\u5f0f\u662f\u8bc6\u522b\u9488\u9053\u7684\u80cc\u666f\uff0c\u708e\u75c7\uff0c\u51fa\u8840\uff0c\u8089\u82bd\uff0c\u542b\u94c1\u8840\u9ec4\u7d20\uff0c\u80c6\u56fa\u9187\u7ed3\u6676\uff0c\u7a7f\u523a\u7684\u75c5\u53f2\u3002<\/p>\n<p>\u4e09\u3001DCIS\u808c\u4e0a\u76ae\u8868\u578b\u53ef\u4ee5\u53d1\u751f\u53d8\u5316<\/p>\n<p>1<\/p>\n<p>2<\/p>\n<p>\u56fe1 DCIS\u808c\u4e0a\u76ae\u67d3\u8272\u5f3a\u5ea6\u548c\u7ec6\u80de\u6570\u91cf\u90fd\u53ef\u4ee5\u51cf\u5c11\uff0cSMMHC\u4e2d\u66f4\u4e3a\u5e38\u89c1\u3002&nbsp;<\/p>\n<p>\u56fe2 \u53d1\u751f\u786c\u5316\u6027\u817a\u75c5\u57fa\u7840\u4e0a\u7684\u4e0d\u5178\u578b\u589e\u751f\uff0c\u6709\u7684\u533a\u57df\u539f\u4f4d\u764c\u3002\u67d0\u4e9b\u7ec6\u80de\u5de2\u5468\u56f4\u808c\u4e0a\u76ae\u7f3a\u5931\u3002\u4f46\u662f\u5176\u4ed6\u808c\u4e0a\u76ae\u6807\u8bb0\u7269\u8bc1\u5b9e\u8fd8\u5b58\u5728\u808c\u4e0a\u76ae\uff0cHE\u5f62\u6001\u4e5f\u53ef\u4ee5\u770b\u5230\u808c\u4e0a\u76ae\u3002<\/p>\n<p>\u56db\u3001\u67d0\u4e9b\u4e73\u817a\u6076\u6027\u80bf\u7624\u53ef\u4ee5\u8868\u8fbe\u808c\u4e0a\u76ae\u6807\u5fd7\u7269<\/p>\n<ul>\n<li>\n<p>\u4e09\u9634\u6027\u4e73\u817a\u764c(\u5316\u751f\u6027\u764c\uff0c\u808c\u4e0a\u76ae\u764c\uff0c\u817a\u6837\u56ca\u6027\u764c\u2026)<\/p>\n<\/li>\n<li>\n<p>\u975e\u4e09\u9634\u6027\u4e73\u817a\u764c<\/p>\n<\/li>\n<li>\n<p>\u6076\u6027\u53f6\u72b6\u80bf\u7624<\/p>\n<\/li>\n<li>\n<p>\u8089\u7624\uff0c\u5982\u8840\u7ba1\u8089\u7624&#8230;<\/p>\n<\/li>\n<li>\n<p>\u6dcb\u5df4\u7624<\/p>\n<\/li>\n<\/ul>\n<p>1<\/p>\n<p>2<\/p>\n<p>\u56fe1 \u8840\u7ba1\u6e90\u6027\u80bf\u7624\uff0c\u4e3b\u8981\u662f\u4e2d\u95f4\u578b\u548c\u6076\u6027\uff0cP63\u53ef\u4ee5\u9633\u6027\u3002\u6240\u4ee5\u4e0d\u8981\u5355\u5355\u56e0\u4e3aP63\u9633\u6027\u5c31\u786e\u8ba4\u662f\u5316\u751f\u6027\u764c\u3002<\/p>\n<p>\u56fe2 \u5f25\u6f2b\u5927B\u7ec6\u80de\u6dcb\u5df4\u7624P63\u9633\u6027\uff0c\u53ef\u80fd\u8ddf\u9884\u540e\u6709\u76f8\u5173\u6027\u3002<\/p>\n<p>1<\/p>\n<p>2<\/p>\n<p>\u56fe1 \u5206\u53f6\u72b6\u80bf\u7624\uff0c\u5c24\u5176\u662f\u4ea4\u754c\u6027\u548c\u6076\u6027\uff0cP63\u548cP40\u4e5f\u53ef\u4ee5\u9633\u6027\uff0c\u6ce8\u610f\u4e0e\u5316\u751f\u6027\u764c\u7684\u9274\u522b\u3002<\/p>\n<p>\u56fe2 \u6076\u6027\u5206\u53f6\u72b6\u80bf\u7624\uff0cP63\u9633\u6027\uff0c\u4f46\u662fAE1\/3\uff0cCK5\/6\u4e5f\u51fa\u73b0\u5c40\u7076\u9633\u6027\u3002<\/p>\n<p>1<\/p>\n<p>2<\/p>\n<p>\u56fe1 P63\u5728\u975e\u4e09\u9634\u6027\u4e73\u817a\u764c\u53ef\u80fd\u6709\u975e\u7279\u5f02\u6027\u67d3\u8272\uff0c\u4f46\u662f\u5728\u4e09\u9634\u6027\u4e73\u817a\u764c\u9633\u6027\u662f\u5b83\u7684\u7279\u70b9\u3002<\/p>\n<p>1<\/p>\n<p>2<\/p>\n<p>\u5bfc\u7ba1\u4e0a\u76ae\u589e\u751f\u6027\u75c5\u53d8\u7684\u8bca\u65ad\u4e0e\u9274\u522b\u8bca\u65ad<\/p>\n<p>\u4e00\u3001CK5\/6\u3001CK14<\/p>\n<p>1\u3001\u9274\u522bUDH\u548cADH<\/p>\n<p>1<\/p>\n<p>2<\/p>\n<p>\u56fe1 UDH CK5\/6\u6591\u9a73\u9633\u6027\uff08\u5982\u4e0a\u56fe\uff09\u3002\u4f46\u662f\u67d0\u4e9b\u4e09\u9634\u6027\u4e73\u817a\u764cCK5\/6\u9633\u6027\uff0cCK14\u9633\u6027\uff0c\u5f62\u6001\u53c8\u5f88\u6e29\u548c\uff0c\u4f1a\u8ba4\u4e3a\u662fUDH\u6216\u826f\u6027\u75c5\u53d8\u3002\u6591\u9a73\u4e0d\u4e00\u7684\u9633\u6027\u66f4\u652f\u6301UDH\uff0c\u800c\u4e09\u9634\u6027\u4e73\u817a\u764cCK5\/6\u5f80\u5f80\u662f\u6bd4\u8f83\u5f3a\u7684\u5f25\u6f2b\u7684\u9633\u6027\u3002\u5bfc\u7ba1\u5185\u589e\u751f\u6027\u75c5\u53d8CK5\/6\u5168\u9634\u6216\u5168\u9633\u90fd\u63d0\u793a\u80bf\u7624\u6027\u589e\u751f\u3002<\/p>\n<p>\u56fe2 \u63a8\u8350CK5\/6\u548cCK14\u3002<\/p>\n<p>2\u3001\u90e8\u5206\u826f\u6027\u5bfc\u7ba1\u5185\u75c5\u53d8\u4e0d\u8868\u8fbeCK5\/6\uff1a<\/p>\n<p>1<\/p>\n<p>2<\/p>\n<p>\u56fe2 \u7537\u6027\u4e73\u817a\u53d1\u80b2\u6216\u5728\u5973\u6027\u7537\u6027\u4e73\u817a\u53d1\u80b2\u6837\u589e\u751f\uff0cCK5\/6\u3001CK14\u5939\u5c42\u9634\u6027\uff0c\u8154\u9762\u6709\u4e00\u5708\u9633\u6027\u3002<\/p>\n<p>\u4e8c\u3001ER<\/p>\n<p>1<\/p>\n<p>2<\/p>\n<p>\u56fe1 UDH\uff1a\u6591\u9a73\u4e0d\u4e00\u9633\u6027\uff0c\u5f3a\u5ea6\u6df1\u6d45\u4e0d\u4e00\u3002<\/p>\n<p>ADH\u548c\u4f4e\u7ea7\u522bDCIS\uff1a\u5f25\u6f2b\u4e00\u81f4\u5f3a\u9633\u6027\u3002<\/p>\n<p>\u56fe2 ER\u548cCK5\/6\u5728\u9274\u522b\u8bca\u65ad\u4e2d\u5e94\u7528\u7684\u524d\u63d0\u662f\u5bfc\u7ba1\u4e0a\u76ae\u6709\u589e\u751f\uff0c\u4e0d\u5efa\u8bae\u4f7f\u7528\u5728\u5355\u817a\u7ba1\u7684\u75c5\u53d8\u3002\u56e0\u6b64\u5728\u4e73\u5934\u72b6\u75c5\u53d8\uff0c\u5f80\u5f80\u662f\u5355\u5c42\u6216\u5c11\u6570\u51e0\u5c42\u7684\u817a\u4e0a\u76ae\uff0c\u4e0d\u9002\u5408\u7528CK5\/6\u548cER\u3002<\/p>\n<p>E-cadherin\u4e0e\u5c0f\u53f6\u764c\u7684\u8bca\u65ad<\/p>\n<p>\u5c0f\u53f6\u764cE-ca\u9634\u6027\uff0cP120\u80de\u6d46\u9633\u6027\u3002<\/p>\n<p>1<\/p>\n<p>2<\/p>\n<p>\u5f02\u5e38\u67d3\u8272\u6a21\u5f0f\uff1a<\/p>\n<p>\u53f3\u4e0b\u56fe\u793a\u6838\u65c1\u9ad8\u5c14\u57fa\u533a\u7740\u8272<\/p>\n<p>1<\/p>\n<p>2<\/p>\n<p>\u56fe1 \u7ecf\u5178\u7684\u5b8c\u6574\u7684\u5f3a\u7684\u7ec6\u80de\u819c\u67d3\u8272\uff0c\u8bca\u65ad\u6d78\u6da6\u6027\u5c0f\u53f6\u764c\u8981\u975e\u5e38\u8c28\u614e\uff0c\u56e0\u4e3a\u6d78\u6da6\u6027\u5bfc\u7ba1\u764c\u4e5f\u53ef\u4ee5\u5355\u6392\u5217\u5175\u6837\uff0c\u540c\u5fc3\u5706\u6837\u6392\u5217\u3002\u771f\u6b63\u7684\u5931\u7c98\u9644\u7684\u5355\u4e2a\u7684\u6563\u5728\u7684\u751f\u957f\u65b9\u5f0f\u66f4\u503e\u5411\u5c0f\u53f6\u764c\u3002<\/p>\n<p>\u56fe2 \u4e09\u56fe\u5747\u4e3a\u80de\u6d46\u7740\u8272\u3002\u5de6\u4e0a\u9760\u8fd1\u7ec6\u80de\u6838\u533a\u57df\u6709\u52a0\u6df1\uff0c\u770b\u4e0a\u53bb\u4e00\u5708\u4e00\u5708\uff0c\u8bef\u8ba4\u4e3a\u80de\u819c\u7740\u8272\uff0c\u4f46\u5b83\u662f\u6655\u67d3\u5f00\u7684\uff0c\u4e0d\u662f\u9510\u5229\u7684\u3002<\/p>\n<p>1<\/p>\n<p>2<\/p>\n<p>\u56fe1 \u5c0f\u53f6\u764c\u7d2f\u53ca\u4e73\u5934\u72b6\u80bf\u7624\uff0c\u4e73\u5934\u72b6\u80bf\u7624\u672c\u8eab\u4f34\u6709\u5bfc\u7ba1\u4e0a\u76ae\u7684\u666e\u901a\u578b\u589e\u751f\uff0c\u6240\u4ee5E-ca\u662f\u6591\u9a73\u4e0d\u4e00\u7684\u9633\u6027\uff0c\u6709\u7684\u662f\u6b8b\u7559\u7684\u5bfc\u7ba1\u4e0a\u76ae\uff0c\u6709\u7684\u662f\u722c\u8fdb\u6765\u7684\u5c0f\u53f6\u7ec6\u80de\u3002<\/p>\n<p>\u56fe2 E-ca\u6bd4\u7ecf\u5178\u7684\u808c\u4e0a\u76ae\u6807\u8bb0\u7269\u67d3\u8272\u8981\u5f31\u3002<\/p>\n<p>1<\/p>\n<p>2<\/p>\n<p>1<\/p>\n<p>2<\/p>\n<p>\u539f\u53d1\u6216\u8f6c\u79fb\u6027\u4e73\u817a\u764c\u7684\u9274\u522b\u8bca\u65ad<\/p>\n<p>\u6709\u52a9\u4e8e\u652f\u6301\u4e73\u817a\u6765\u6e90\u7684\u6807\u5fd7\u7269\uff1aGATA3\u3001Mammaglobin\u3001GCDFP15\u3001ER\u3001PR\u3001CK7\uff08CK7 \uff0cCK20-\uff09\u3002<\/p>\n<p>\u5fc5\u987b\u4f7f\u7528\u4e00\u7ec4\u514d\u75ab\u7ec4\u5316\uff0c\u719f\u6089\u5404\u79cd\u6297\u4f53\u7684\u9633\u6027\u8c31\u7cfb\u3002<\/p>\n<p>1<\/p>\n<p>2<\/p>\n<p>\u4e09\u9634\u6027\u4e73\u817a\u764c\u53ef\u4ee5\u7528SOX10\u4ee3\u66ff\u4e0a\u9762\u4e09\u4e2a\u3002<\/p>\n<p>SOX10\u5728\u6b63\u5e38\u4e73\u817a\uff1a\u808c\u4e0a\u76ae\u8868\u8fbe\uff0c\u7ba1\u8154\u4e0a\u76ae\u9634\u6027\u3002\u4e5f\u8868\u8fbe\u4e8e\u8272\u7d20\u7ec6\u80de\uff08\u6076\u9ed1\uff09\u3001\u795e\u7ecf\u9798\u7ec6\u80de\u3001\u808c\u4e0a\u76ae\u7ec6\u80de\u7b49\u3002<\/p>\n<p>1<\/p>\n<p>2<\/p>\n<p>\u56fe1 \u6709\u4e9b\u4e09\u9634\u6027\u4e73\u817a\u764cSOX10\u8868\u8fbe\u7387\u6bd4\u8f83\u4f4e\u3002<\/p>\n<p>1<\/p>\n<p>2<\/p>\n<p>\u56fe1 GATA3\u654f\u611f\u6027\u4f18\u4e8e\u524d\u9762\u4e24\u4e2a\u3002\u5728\u6fc0\u7d20\u53d7\u4f53\u9633\u6027\u7684\u4e73\u817a\u764c\u662f\u975e\u5e38\u654f\u611f\u7684\u6807\u8bb0\u7269\u3002&nbsp;<\/p>\n<p>1<\/p>\n<p>2<\/p>\n<p>\u4e73\u817a\u7c98\u6db2\u764cWT-1\u9633\u6027\u3002<\/p>\n<p>\u6d78\u6da6\u6027\u5bfc\u7ba1\u764c\u4f34\u7c98\u6db2\u5206\u6ccc\uff0c\u6d78\u6da6\u6027\u5fae\u4e73\u5934\u72b6\u764c\u4f34\u7c98\u6db2\u5206\u6ccc\u7684WT-1\u9634\u6027\u3002<\/p>\n<p>\u6700\u65b0\u53d1\u73b0\u7684\u4e00\u79cd\u4e73\u817a\u7279\u5f02\u800c\u654f\u611f\uff08\uff1e90%\uff09\u7684\u6807\u8bb0\u7269-TRPS-1\uff08\u6838\uff09\u3002\u53c2\u4e0e\u4e73\u817a\u764c\u7684\u53d1\u751f\u53d1\u5c55\u4ee5\u53ca\u9aa8\u3001\u8f6f\u9aa8\u3001\u80be\u810f\u7684\u80da\u80ce\u53d1\u80b2\u3002<\/p>\n<p>\u80bf\u7624\u8bca\u65ad\u6307\u6807<\/p>\n<p>1<\/p>\n<p>2<\/p>\n<p>IDH2(\u514b\u9686\u53f7\uff1a11C8B1)\uff1a\u5f25\u6f2b\u5f3a\u9633\u6027\u7684\u80de\u6d46\u9897\u7c92\u72b6\u67d3\u8272\u6a21\u5f0f\uff0c\u53ef\u8f85\u52a9\u8bca\u65ad\u4f34\u6709\u6781\u6027\u7ffb\u8f6c\u7684\u9ad8\u7ec6\u80de\u764c\u3002<\/p>\n<p>\u6709\u65e0\u8109\u7ba1\u5185\u764c\u6813<\/p>\n<p>CD31\u2014\u8840\u7ba1\u5185\u76ae\u6807\u8bb0\u7269\uff0c\u7279\u5f02\u6027\u597d\u3002\u80de\u6d46 \u80de\u819c\u3002<\/p>\n<p>CD34\u2014\u8840\u7ba1\u5185\u76ae\u6807\u8bb0\u7269\uff0c\u7279\u5f02\u6027\u5dee\u3002\u6dcb\u5df4\u7ba1\u5185\u76ae\u4e5f\u53ef\u7740\u8272\u3002\u4e73\u817a\u95f4\u8d28\u7ec6\u80de\u4e5f\u662f\u5f31\u9633\u6027\u3002\u80de\u6d46 \u80de\u819c\u3002<\/p>\n<p>D240\u2014\u6dcb\u5df4\u7ba1\u5185\u76ae\u6807\u8bb0\uff0c\u808c\u4e0a\u76ae\u4e5f\u53ef\u7740\u8272\u3002\u80de\u819c\u7740\u8272\u3002<\/p>\n<p>\u6cbb\u7597\u76f8\u5173\u7684\u514d\u75ab\u7ec4\u5316\u8fdb\u5c55<\/p>\n<p>\u4e0b\u8282\u518d\u89c1\u5427~<\/p>\n<p>\u672c\u8282\u5185\u5bb9\u6765\u81ea\u6768\u6587\u6d9b\u6559\u6388\u548c\u6885\u653e\u6559\u6388\uff0c\u5982\u6709\u4fb5\u6743\uff0c\u8bf7\u8054\u7cfb\u5c0f\u7f16\u5220\u9664\u3002<\/p>\n<p>AUTUMN<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u4e09\u89d2\u5f62\u9ad8\u5ea6\u4ee3\u8868\u8868\u8fbe\u7684\u5f3a\u5ea6\u3002 CK5\u3001CK5\/6\u3001CK14\u9ad8\u5206\u5b50\u91cf\u89d2\u86cb\u767d\uff0c\u5e72\u7ec6\u80de\u8868 &hellip; <a href=\"http:\/\/zydq.1006ss.com\/?p=27846\">\u7ee7\u7eed\u9605\u8bfb <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[70],"tags":[],"class_list":["post-27846","post","type-post","status-publish","format-standard","hentry","category-70"],"_links":{"self":[{"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=\/wp\/v2\/posts\/27846","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=27846"}],"version-history":[{"count":0,"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=\/wp\/v2\/posts\/27846\/revisions"}],"wp:attachment":[{"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=27846"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=27846"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/zydq.1006ss.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=27846"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}