\u3010\u51fa\u5904\u3011\u51fa\u81ea\u300a\u4e91\u5357\u4e2d\u8349\u836f\u9009\u300b\u3002<\/p>\n
\u3010\u62fc\u97f3\u540d\u3011D\u00e0 C\u01ceo W\u016b<\/p>\n
\u3010\u82f1\u6587\u540d\u3011Root of Vilmorin Monkshood<\/p>\n
\u3010\u522b\u540d\u3011\u6606\u660e\u5835\u5587\u3001\u8349\u4e4c<\/p>\n
\u3010\u6765\u6e90\u3011
\u836f\u6750\u57fa\u6e90\uff1a\u4e3a\u6bdb\u831b\u79d1\u690d\u7269\u9ec4\u8349\u4e4c\u548c\u819d\u74e3\u4e4c\u5934\u7684\u5757\u6839\u3002
\u62c9\u4e01\u690d\u7269\u52a8\u7269\u77ff\u7269\u540d\uff1a1.Aconitum vilmorinianum Kom.[A.mairei Levl.]2.Aconitum geniculatum Fletcher et Lauener
\u91c7\u6536\u548c\u50a8\u85cf\uff1a\u79cb\u51ac\u5b63\u91c7\u6316\uff0c\u53bb\u6b8b\u830e\u3001\u987b\u6839\uff0c\u7f6e\u6cb8\u6c34\u716e4H\uff0c\u6216\u7528\u77f3\u7070\u6c34\u6d78\u6ce17-10d\uff0c\u6e05\u6c34\u6f023d\uff0c\u6bcf\u65e5\u6362\u6c342\u6b21\uff0c\u6652\u5e72\u5907\u7528\u3002<\/p>\n
\u3010\u539f\u5f62\u6001\u3011
1.\u9ec4\u8349\u4e4c\uff0c\u591a\u5e74\u751f\u660c\u672c\u3002\u5757\u6839\u692d\u5706\u7403\u5f62\u6216\u80e1\u841d\u535c\u5f62\uff0c\u957f2.5-7cm\uff0c\u76f4\u5f84\u7ea61cm\u3002\u830e\u7f20\u7ed5\uff0c\u957f\u8fbe4m\uff0c\u6709\u5206\u679d\uff0c\u758f\u88ab\u53cd\u66f2\u77ed\u67d4\u6bdb\u6216\u51e0\u65e0\u6bdb\u3002\u53f6\u4e92\u751f\uff1b\u53f6\u67c4\u4e0e\u53f6\u7247\u8fd1\u7b49\u957f\uff1b\u53f6\u7247\u4e94\u89d2\u5f62\uff0c\u957f5-10cm\uff0c\u5bbd8-16cm\uff0c\u57fa\u90e8\u5bbd\u5fc3\u5f62\uff0c3\u5168\u88c2\u6216\u8fbe\u8fd1\u57fa\u90e8\uff0c\u4e2d\u592e\u5168\u88c2\u7247\u5bbd\u83f1\u5f62\uff0c\u4fa7\u5168\u88c2\u7247\u659c\u6247\u5f62\uff0c\u4e0d\u7b492\u88c2\u7565\u8d85\u8fc7\u4e2d\u90e8\uff0c\u4e0a\u9762\u758f\u88ab\u7d27\u8d34\u7684\u77ed\u67d4\u6bdb\uff0c\u4e0b\u9762\u53f6\u8109\u758f\u88ab\u77ed\u67d4\u6bdb\u3002\u82b1\u5e8f\u67093-6\u6735\u82b1\uff0c\u82b1\u5e8f\u8f74\u548c\u82b1\u6897\u5bc6\u88ab\u6de1\u9ec4\u8272\u53cd\u66f2\u77ed\u67d4\u6bdb\uff1b\u82de\u7247\u7ebf\u5f62\uff1b\u82b1\u6897\u957f2-4cm\uff1b\u5c0f\u82de\u7247\u751f\u82b1\u6897\u4e2d\u90e8\u6216\u4e0b\u90e8\uff0c\u72ed\u7ebf\u5f62\uff0c\u957f3-5mm\uff0c\u5bc6\u88ab\u77ed\u67d4\u6bdb\uff1b\u82b1\u4e24\u6027\uff0c\u4e24\u4fa7\u5bf9\u79f0\uff1b\u843c\u72475\uff0c\u82b1\u74e3\u72b6\uff0c\u4e0a\u843c\u7247\u9ad8\u76d4\u5f62\uff0c\u9ad81.7-2cm\uff0c\u4e0b\u7f181.5-1.6cm\uff0c\u4e0e\u5916\u7f18\u6bdb\uff1b\u82b1\u74e32\uff0c\u5507\u957f\u7ea66mm\uff0c\u5fae\u51f9\uff0c\u8ddd\u957f\u7ea63mm\uff0c\u5411\u540e\u5f2f\u66f2\uff0c\u65e0\u6bdb\uff1b\u96c4\u854a\u591a\u6570\uff0c\u82b1\u4e1d\u5168\u7f18\u6216\u67092\u679a\u5c0f\u9f7f\uff0c\u65e0\u6bdb\uff1b\u5fc3\u76ae5\uff0c\u65e0\u6bdb\u6216\u4e0a\u90e8\u758f\u751f\u77ed\u6bdb\u3002\u83b4\u8456\u679c\uff0c\u957f1.6-1.8cm\uff0c\u65e0\u5c3e\u3002\u79cd\u5b50\u591a\u6570\uff0c\u4e09\u68f1\u5f62\uff0c\u957f\u7ea63mm\uff0c\u53ea\u5728\u4e00\u9762\u5bc6\u751f\u6a2a\u819c\u7fc5\u3002\u82b1\u671f8-9\u6708\uff0c\u679c\u671f9-10\u6708\u3002
2.\u819d\u74e3\u4e4c\u5934\uff0c\u591a\u5e74\u751f\u8349\u672c\uff0c\u9ad8\u7ea61m\u3002\u830e\u76f4\u7acb\uff0c\u5177\u5206\u679d\uff0c\u65e0\u6bdb\u3002\u53f6\u4e92\u751f\uff1b\u53f6\u67c4\u957f3-5cm\uff0c\u57fa\u90e8\u5177\u9798\uff0c\u65e0\u6bdb\uff1b\u53f6\u7247\u5706\u4e94\u89d2\u5f62\uff0c\u957f\u5bbd\u5747\u4e3a6-10cm\uff0c\u57fa\u90e8\u5fc3\u5f62\uff0c3\u6df1\u88c2\u81f3\u8fd1\u57fa\u90e8\uff0c\u4e2d\u592e\u6df1\u88c2\u7247\u83f1\u5f62\uff0c3\u88c2\uff0c\u4fa7\u6df1\u88c2\u7247\u659c\u6247\u5f62\uff0c2\u6df1\u88c2\u8d85\u8fc7\u4e2d\u90e8\uff0c\u4e0a\u9762\u53ea\u8109\u4e0a\u758f\u88ab\u7d27\u8d34\u7684\u77ed\u67d4\u6bdb\uff0c\u4e0b\u9762\u65e0\u6bdb\u3002\u603b\u72b6\u82b1\u5e8f\u8fd1\u4f1e\u623f\u72b6\uff0c\u957f3-8.5cm\uff0c\u6709\u82b12-8\u6735\uff1b\u82b1\u5e8f\u8f74\u548c\u82b1\u6897\u5747\u65e0\u6bdb\uff1b\u82de\u7247\u53f6\u72b6\uff1b\u82b1\u6897\u957f2-4cm\uff1b\u5c0f\u82de\u7247\u751f\u82b1\u6897\u4e2d\u90e8\uff0c\u7ebf\u5f62\uff0c\u957f3.5-4.5cm\uff0c\u65e0\u6bdb\u3002\u82b1\u4e24\u6027\uff0c\u8fd1\u4e24\u4fa7\u5bf9\u79f0\uff1b\u82b1\u843c5\uff0c\u82b1\u90e8\uff0c\u7ebf\u5f62\uff0c\u957f3.5-4.5cm\uff0c\u65e0\u6bdb\u3002\u82b1\u4e24\u6027\uff0c\u8fd1\u4e24\u4fa7\u5bf9\u79f0\uff1b\u82b1\u843c5\uff0c\u82b1\u74e3\u72b6\uff0c\u4e0a\u843c\u7247\u9ad8\u76d4\u5f62\uff0c\u9ad8\u7ea61.6cm\uff0c\u4e0b\u7f18\u957f1.5-1.8cm\uff0c\u5916\u7f18\u8fd1\u5782\u76f4\uff0c\u4e0e\u4e0b\u7f18\u5f62\u6210\u4e0d\u660e\u663e\u7684\u77ed\u5599\u6216\u51e0\u65e0\u5599\uff0c\u4fa7\u843c\u7247\u5bbd\u5012\u5375\u5f62\uff0c\u957f1.3-1.4cm\uff0c\u5185\u9762\u5148\u7aef\u819d\u72b6\u5f2f\u66f2\uff0c\u74e3\u7247\u957f\u7ea61.1cm\uff0c\u5507\u957f4.5mm\uff0c\u672b\u7aef2\u6d45\u88c2\uff0c\u8ddd\u957f\u7ea62.5mm\uff0c\u5411\u540e\u5f2f\u66f2\uff0c\u65e0\u6bdb\uff1b\u96c4\u854a\u591a\u6570\uff0c\u82b1\u4e1d\u5168\u7f18\u6216\u51772\u679a\u5c0f\u7259\u9f7f\uff0c\u65e0\u6bdb\uff1b\u5fc3\u76ae5\uff0c\u65e0\u6bdb\u3002\u83b4\u8456\u679c\u3002\u79cd\u5b50\u591a\u6570\u3002\u82b1\u671f7\u6708\uff0c\u679c\u671f8\u6708\u3002<\/p>\n
\u3010\u751f\u5883\u5206\u5e03\u3011
\u751f\u6001\u73af\u5883\uff1a1.\u751f\u4e8e\u6d77\u62d42100-2500m\u7684\u5c71\u5730\u704c\u6728\u4e1b2.\u4e2d\u751f\u4e8e\u6d77\u62d43200m\u7684\u5c71\u5730\u3002
\u8d44\u6e90\u5206\u5e03\uff1a1.\u5206\u5e03\u4e8e\u56db\u5ddd\u4f1a\u7406\u3001\u8d35\u5dde\u897f\u90e8\u548c\u4e91\u5357\u4e2d\u90e8\u3002
2.\u5206\u5e03\u4e8e\u56db\u5ddd\u666e\u683c\uff0c\u4e91\u5357\u4e1c\u5317\u90e8\u3002<\/p>\n
\u3010\u6027\u72b6\u3011
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\u7c89\u672b\u7279\u5f81\uff1a\u9ec4\u8349\u4e4c\uff0c1.\u77f3\u7ec6\u80de\u957f\u65b9\u5f62\u3001\u957f\u6761\u5f62\u6216\u957f\u5375\u5f62\uff0c\u957f32-1408\u03bcm\uff0c\u76f4\u5f8422-52\u03bcm\uff0c\u5b54\u6c9f\u7a00\u758f\uff0c\u7eb9\u5b54\u660e\u663e\u30022.\u6dc0\u7c89\u7c92\u5355\u7c92\u7c7b\u692d\u5706\u5f62\uff0c\u4e00\u7aef\u6709\u5c0f\u51f9\u6216\u7c7b\u5706\u5f62\u3001\u7c73\u7c92\u72b6\uff0c\u76f4\u5f84\u5c0f\u7c92\u7ea64\u03bcm\uff0c\u5927\u7c9216-44\u03bcm\uff0c\u8110\u70b9\u591a\u6570\u4e0d\u660e\u663e\uff1b\u590d\u7c92\u4e3a4\u5206\u7c92\u7ec4\u6210\u3002<\/p>\n
\u3010\u5316\u5b66\u6210\u4efd\u3011
1.\u9ec4\u8349\u4e4c\uff0c\u6839\u542b\u9ec4\u8349\u4e4c\u78b1\u7532 \uff08vilmorrianineA\uff09\uff0c\u591a\u6839\u4e4c\u5934\u78b1(daracoline)\uff0c\u6ec7\u4e4c\u78b1(yunaconitine)\uff0c\u9ec4\u8349\u4e4c\u78b1\u4e01(vilmorrianine D)\uff0c\u9ec4\u8349\u4e4c\u916e\u78b1(vilmorrianone0\uff0c\u5854\u62c9\u5b9a(talatizidine)\uff0c\u5f02\u5854\u62c9\u5b9a(isotalaftizidine)\uff0c\u5854\u62c9\u80fa(talatisamine)\u3002
2.\u819d\u74e3\u4e4c\u5934\uff0c\u6839\u542b\u6ec7\u4e4c\u78b1 \uff08\u8bb3\u75be\u5fcc\u533b\uff09,8-\u53bb\u4e59\u9170\u6ec7\u4e4c\u78b1(8-deacetyl-yunaconitine)\uff0c\u5854\u62c9\u80fa(talatisamine)\uff0c\u9ec4\u8349\u4e4c\u78b1\u4e19(vilmorrianine C)\uff0c\u5c55\u82b1\u4e4c\u5934\u5b81(chasmanine)\uff0c\u819d\u74e3\u4e4c\u5934\u78b1(geniconitine)\uff0c\u7c97\u830e\u4e4c\u5934\u78b1\u7532(crassicauline A)\u3002<\/p>\n
\u3010\u836f\u7406\u4f5c\u7528\u3011
1.\u9547\u75db\u4f5c\u7528\uff0c\u9ec4\u8349\u4e4c\u6d78\u818f6.2-7.5mg\/kg\u704c\u80c3\u5c0f\u9f20\u70ed\u677f\u6cd5\u5b9e\u9a8c\u6709\u9547\u75db\u4f5c\u7528\uff0c\u5bf9\u9152\u77f3\u9178\u9511\u94be\u8179\u8154\u6ce8\u5c04\u7684 \u81f4\u5c0f\u9f20\u626d\u4f53\u53cd\u5e94\u4e5f\u6709\u6291\u5236\u4f5c\u7528\u3002
2.\u5bf9\u5fc3\u810f\u7684\u4f5c\u7528\uff0c\u653f\u515a\u5bb6\u5154\u704c\u670d\u9ec4\u8349\u4e4c7.5mg\/kg\u5bf9\u5fc3\u810f\u6d3b\u52a8\u672a\u89c1\u5f71\u54cd\uff0c5\u53ea\u5bb6\u5154\u4ec5\u4e8e\u836f\u540e2h\u73b0\u73b0T\u6ce2\u7a0d\u4f4e\uff0c\u4f46\u4ecd\u5448\u7aa6\u6027\u5fc3\u7387\u3002
3.\u6bd2\u6027\uff0c\u6ec7\u4e4c\u78b1\u6bd2\u6027\u5f88\u5927\uff0c\u5bf9\u5c0f\u9f20\u8179\u8154\u6ce8\u5c04LD50\u4e3a0.585mg\/kg\uff0c\u5927\u9f20\u3001\u72d7\u9759\u8109\u6ce8\u5c04\u7684\u81f4\u6b7b\u91cf\u5206\u522b\u4e3a0.05mg\/kg\u548c0.03mg\/kg\u3002<\/p>\n
\u3010\u9274\u522b\u3011\u7406\u5316\u9274\u522b\uff0c\u8584\u5c42\u8272\u8c31\uff1a\u53d6\u672c\u54c1\u7c89\u672b\u7ea61g\uff0c\u52a010%\u6c28\u6eb6\u6db21ml\u3001\u4e59\u919a10ml\uff0c\u51b7\u6d7824h\uff0c\u6ee4\u8fc7\u3002\u6ee4\u6db2\u6325\u5e72\uff0c\u6b8b\u6e23\u4ee5\u4e8c\u6c2f\u7532\u70f7\u6d17\u51651ml\u5bb9\u91cf\u74f6\u4e2d\u7684\u5b9a\u5bb9\uff0c\u4f5c\u706f\u4ea7\u54c1\u6eb6\u6db2\u3002\u53e6\u53d6\u6ec7\u4e4c\u78b1\u3001\u5854\u62c9\u4e4c\u5934\u80fa\u5236\u6210\u54041mg\/1ml\u7684\u4e8c\u6c2f\u7532\u70f7\u6df7\u5408\u6eb6\u6db2\uff0c\u4f5c\u4e3a\u5bf9\u7167\u54c1\u6eb6\u6db2\u3002\u5728\u9ad8\u6548\u7845\u80f6GF254\u8584\u5c42\u677f\u4e0a\u70b9\u6837\u54c1\u548c\u5bf9\u7167\u54c1\u6eb6\u6db2\u54043\u03bcl\uff0c\u4ee5\u73af\u5df2\u70f7–\u4e59\u9178\u4e59\u916f-\u4e8c\u4e59\u80fa(8:1:1)\u5c55\u5f00\uff0c\u53d6\u51fa\uff0c\u667e\u5e72\uff0c\u55b7\u4ee5\u7898\u5316\u94cb\u94be\u3001\u7898\u5316\u94be\u7898\u8bd5\u6db2\u7b49\u5bb9\u6df7\u5408\u6db2\u663e\u8272\u3002\u4f9b\u8bd5\u54c1\u8272\u8c31\u5728\u4e0e\u5bf9\u7167\u54c1\u8272\u8c31\u76f8\u5e86\u4f4d\u7f6e\u4e0a\uff0c\u663e\u76f8\u540c\u989c\u8272\u6591\u70b9\u3002<\/p>\n
\u3010\u70ae\u5236\u3011\u53d6\u4e4c\u5934\u7528\u7518\u8349\u3001\u9ed1\u8c46\u7684\u714e\u6c41\u53ca\u751f\u59dc\u6c41\u6d78\u6ce1\u81f3\u900f\u5fc3\uff0c\u635e\u51fa\uff0c\u84b812\u5c0f\u65f6\u540e\uff0c\u53d6\u51fa\uff0c\u6652\u5e72\u3002<\/p>\n
\u3010\u6027\u5473\u3011\u5473\u8f9b\uff1b\u82e6\uff1b\u6027\u70ed\uff1b\u5927\u6bd2<\/p>\n
\u3010\u529f\u80fd\u4e3b\u6cbb\u3011\u795b\u98ce\u6563\u5bd2\uff1b\u6d3b\u8840\u6b62\u75db\uff1b\u89e3\u6bd2\u6d88\u80bf\u3002\u4e3b\u98ce\u5bd2\u6e7f\u75f9\uff1b\u624b\u8db3\u53a5\u51b7\uff1b\u8dcc\u6253\u635f\u4f24\uff1b\u75ae\u6bd2<\/p>\n
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\u3010\u6458\u5f55\u3011\u300a\u4e2d\u534e\u672c\u8349\u300b<\/p>\n","protected":false},"excerpt":{"rendered":"
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